Amino acid dipepetide frequency for Moraxella catarrhalis (strain BBH18)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.015AlaAla: 7.015 ± 0.143	1.212AlaCys: 1.212 ± 0.047	5.459AlaAsp: 5.459 ± 0.11	4.038AlaGlu: 4.038 ± 0.099	3.341AlaPhe: 3.341 ± 0.09	6.353AlaGly: 6.353 ± 0.111	2.217AlaHis: 2.217 ± 0.062	6.688AlaIle: 6.688 ± 0.111	6.105AlaLys: 6.105 ± 0.134	9.532AlaLeu: 9.532 ± 0.153	2.899AlaMet: 2.899 ± 0.075	4.11AlaAsn: 4.11 ± 0.105	2.82AlaPro: 2.82 ± 0.082	4.138AlaGln: 4.138 ± 0.108	3.724AlaArg: 3.724 ± 0.098	4.731AlaSer: 4.731 ± 0.115	4.974AlaThr: 4.974 ± 0.095	6.278AlaVal: 6.278 ± 0.112	1.152AlaTrp: 1.152 ± 0.051	2.82AlaTyr: 2.82 ± 0.071	0.0AlaXaa: 0.0 ± 0.0
Cys	0.761CysAla: 0.761 ± 0.04	0.128CysCys: 0.128 ± 0.014	0.671CysAsp: 0.671 ± 0.036	0.438CysGlu: 0.438 ± 0.031	0.41CysPhe: 0.41 ± 0.028	0.847CysGly: 0.847 ± 0.036	0.494CysHis: 0.494 ± 0.033	0.648CysIle: 0.648 ± 0.037	0.334CysLys: 0.334 ± 0.024	1.082CysLeu: 1.082 ± 0.048	0.197CysMet: 0.197 ± 0.02	0.278CysAsn: 0.278 ± 0.023	0.498CysPro: 0.498 ± 0.034	0.695CysGln: 0.695 ± 0.039	0.442CysArg: 0.442 ± 0.034	0.466CysSer: 0.466 ± 0.03	0.496CysThr: 0.496 ± 0.029	0.682CysVal: 0.682 ± 0.034	0.083CysTrp: 0.083 ± 0.012	0.355CysTyr: 0.355 ± 0.026	0.0CysXaa: 0.0 ± 0.0
Asp	5.365AspAla: 5.365 ± 0.108	0.554AspCys: 0.554 ± 0.031	4.29AspAsp: 4.29 ± 0.099	4.6AspGlu: 4.6 ± 0.105	2.52AspPhe: 2.52 ± 0.073	4.316AspGly: 4.316 ± 0.101	1.253AspHis: 1.253 ± 0.056	4.523AspIle: 4.523 ± 0.104	4.126AspLys: 4.126 ± 0.095	5.066AspLeu: 5.066 ± 0.094	1.601AspMet: 1.601 ± 0.057	2.661AspAsn: 2.661 ± 0.078	1.738AspPro: 1.738 ± 0.06	1.774AspGln: 1.774 ± 0.063	2.212AspArg: 2.212 ± 0.06	2.798AspSer: 2.798 ± 0.07	3.64AspThr: 3.64 ± 0.08	3.568AspVal: 3.568 ± 0.09	0.842AspTrp: 0.842 ± 0.045	2.142AspTyr: 2.142 ± 0.07	0.0AspXaa: 0.0 ± 0.0
Glu	4.125GluAla: 4.125 ± 0.098	0.451GluCys: 0.451 ± 0.03	2.276GluAsp: 2.276 ± 0.073	2.215GluGlu: 2.215 ± 0.083	2.183GluPhe: 2.183 ± 0.062	2.648GluGly: 2.648 ± 0.079	1.556GluHis: 1.556 ± 0.059	3.674GluIle: 3.674 ± 0.081	2.636GluLys: 2.636 ± 0.08	5.387GluLeu: 5.387 ± 0.128	1.46GluMet: 1.46 ± 0.054	2.362GluAsn: 2.362 ± 0.072	1.894GluPro: 1.894 ± 0.07	2.898GluGln: 2.898 ± 0.068	3.067GluArg: 3.067 ± 0.093	2.554GluSer: 2.554 ± 0.067	2.569GluThr: 2.569 ± 0.08	3.294GluVal: 3.294 ± 0.091	0.567GluTrp: 0.567 ± 0.036	1.774GluTyr: 1.774 ± 0.066	0.0GluXaa: 0.0 ± 0.0
Phe	3.555PheAla: 3.555 ± 0.098	0.562PheCys: 0.562 ± 0.033	3.268PheAsp: 3.268 ± 0.078	2.398PheGlu: 2.398 ± 0.07	1.763PhePhe: 1.763 ± 0.058	3.946PheGly: 3.946 ± 0.084	0.804PheHis: 0.804 ± 0.036	3.001PheIle: 3.001 ± 0.086	1.68PheLys: 1.68 ± 0.056	3.523PheLeu: 3.523 ± 0.088	1.146PheMet: 1.146 ± 0.048	1.847PheAsn: 1.847 ± 0.055	0.998PhePro: 0.998 ± 0.047	0.919PheGln: 0.919 ± 0.04	1.355PheArg: 1.355 ± 0.054	2.43PheSer: 2.43 ± 0.066	1.966PheThr: 1.966 ± 0.07	2.646PheVal: 2.646 ± 0.081	0.605PheTrp: 0.605 ± 0.042	1.505PheTyr: 1.505 ± 0.054	0.0PheXaa: 0.0 ± 0.0
Gly	5.149GlyAla: 5.149 ± 0.123	0.772GlyCys: 0.772 ± 0.035	3.672GlyAsp: 3.672 ± 0.09	4.034GlyGlu: 4.034 ± 0.098	3.371GlyPhe: 3.371 ± 0.077	4.884GlyGly: 4.884 ± 0.116	1.605GlyHis: 1.605 ± 0.051	5.111GlyIle: 5.111 ± 0.111	3.974GlyLys: 3.974 ± 0.093	7.114GlyLeu: 7.114 ± 0.112	2.244GlyMet: 2.244 ± 0.073	2.54GlyAsn: 2.54 ± 0.084	0.896GlyPro: 0.896 ± 0.04	2.909GlyGln: 2.909 ± 0.074	3.362GlyArg: 3.362 ± 0.083	3.625GlySer: 3.625 ± 0.094	3.397GlyThr: 3.397 ± 0.082	5.91GlyVal: 5.91 ± 0.124	0.776GlyTrp: 0.776 ± 0.04	2.563GlyTyr: 2.563 ± 0.064	0.0GlyXaa: 0.0 ± 0.0
His	2.582HisAla: 2.582 ± 0.071	0.267HisCys: 0.267 ± 0.022	1.496HisAsp: 1.496 ± 0.059	1.411HisGlu: 1.411 ± 0.061	1.056HisPhe: 1.056 ± 0.049	1.898HisGly: 1.898 ± 0.059	1.334HisHis: 1.334 ± 0.063	1.93HisIle: 1.93 ± 0.064	1.246HisLys: 1.246 ± 0.056	2.725HisLeu: 2.725 ± 0.076	0.532HisMet: 0.532 ± 0.03	0.977HisAsn: 0.977 ± 0.042	1.396HisPro: 1.396 ± 0.055	1.755HisGln: 1.755 ± 0.065	1.422HisArg: 1.422 ± 0.056	1.37HisSer: 1.37 ± 0.051	1.772HisThr: 1.772 ± 0.066	1.304HisVal: 1.304 ± 0.05	0.368HisTrp: 0.368 ± 0.025	0.906HisTyr: 0.906 ± 0.04	0.0HisXaa: 0.0 ± 0.0
Ile	6.75IleAla: 6.75 ± 0.111	0.81IleCys: 0.81 ± 0.038	5.017IleAsp: 5.017 ± 0.094	3.974IleGlu: 3.974 ± 0.092	2.789IlePhe: 2.789 ± 0.085	5.331IleGly: 5.331 ± 0.112	1.977IleHis: 1.977 ± 0.065	5.092IleIle: 5.092 ± 0.11	4.256IleLys: 4.256 ± 0.083	6.415IleLeu: 6.415 ± 0.117	1.672IleMet: 1.672 ± 0.061	3.563IleAsn: 3.563 ± 0.091	2.539IlePro: 2.539 ± 0.065	2.706IleGln: 2.706 ± 0.074	2.86IleArg: 2.86 ± 0.071	4.613IleSer: 4.613 ± 0.102	4.352IleThr: 4.352 ± 0.087	4.036IleVal: 4.036 ± 0.093	0.804IleTrp: 0.804 ± 0.042	2.131IleTyr: 2.131 ± 0.076	0.0IleXaa: 0.0 ± 0.0
Lys	5.072LysAla: 5.072 ± 0.111	0.299LysCys: 0.299 ± 0.025	3.397LysAsp: 3.397 ± 0.088	2.379LysGlu: 2.379 ± 0.079	1.915LysPhe: 1.915 ± 0.05	2.982LysGly: 2.982 ± 0.079	1.426LysHis: 1.426 ± 0.058	3.82LysIle: 3.82 ± 0.091	3.243LysLys: 3.243 ± 0.085	5.376LysLeu: 5.376 ± 0.088	1.481LysMet: 1.481 ± 0.045	3.114LysAsn: 3.114 ± 0.088	2.648LysPro: 2.648 ± 0.084	3.084LysGln: 3.084 ± 0.082	2.46LysArg: 2.46 ± 0.075	3.709LysSer: 3.709 ± 0.084	3.766LysThr: 3.766 ± 0.093	3.305LysVal: 3.305 ± 0.084	0.504LysTrp: 0.504 ± 0.033	1.484LysTyr: 1.484 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	9.944LeuAla: 9.944 ± 0.153	1.026LeuCys: 1.026 ± 0.041	6.066LeuAsp: 6.066 ± 0.113	4.397LeuGlu: 4.397 ± 0.123	3.651LeuPhe: 3.651 ± 0.088	7.33LeuGly: 7.33 ± 0.12	2.191LeuHis: 2.191 ± 0.071	7.118LeuIle: 7.118 ± 0.14	5.472LeuLys: 5.472 ± 0.095	9.561LeuLeu: 9.561 ± 0.186	2.965LeuMet: 2.965 ± 0.079	4.585LeuAsn: 4.585 ± 0.092	5.297LeuPro: 5.297 ± 0.1	3.587LeuGln: 3.587 ± 0.088	3.837LeuArg: 3.837 ± 0.084	7.924LeuSer: 7.924 ± 0.139	6.274LeuThr: 6.274 ± 0.109	6.374LeuVal: 6.374 ± 0.119	1.126LeuTrp: 1.126 ± 0.047	2.7LeuTyr: 2.7 ± 0.069	0.0LeuXaa: 0.0 ± 0.0
Met	2.881MetAla: 2.881 ± 0.081	0.188MetCys: 0.188 ± 0.017	1.261MetAsp: 1.261 ± 0.052	0.778MetGlu: 0.778 ± 0.042	0.784MetPhe: 0.784 ± 0.043	2.123MetGly: 2.123 ± 0.073	0.599MetHis: 0.599 ± 0.033	2.041MetIle: 2.041 ± 0.062	1.357MetLys: 1.357 ± 0.046	2.721MetLeu: 2.721 ± 0.063	1.062MetMet: 1.062 ± 0.05	1.391MetAsn: 1.391 ± 0.054	1.492MetPro: 1.492 ± 0.049	1.345MetGln: 1.345 ± 0.054	1.174MetArg: 1.174 ± 0.041	1.926MetSer: 1.926 ± 0.065	2.219MetThr: 2.219 ± 0.057	1.888MetVal: 1.888 ± 0.055	0.216MetTrp: 0.216 ± 0.02	0.611MetTyr: 0.611 ± 0.039	0.0MetXaa: 0.0 ± 0.0
Asn	3.955AsnAla: 3.955 ± 0.092	0.408AsnCys: 0.408 ± 0.024	2.482AsnAsp: 2.482 ± 0.066	2.174AsnGlu: 2.174 ± 0.071	1.819AsnPhe: 1.819 ± 0.05	2.587AsnGly: 2.587 ± 0.075	1.776AsnHis: 1.776 ± 0.061	3.196AsnIle: 3.196 ± 0.083	2.518AsnLys: 2.518 ± 0.077	4.444AsnLeu: 4.444 ± 0.092	0.958AsnMet: 0.958 ± 0.04	2.016AsnAsn: 2.016 ± 0.087	2.539AsnPro: 2.539 ± 0.072	2.819AsnGln: 2.819 ± 0.087	2.007AsnArg: 2.007 ± 0.06	2.266AsnSer: 2.266 ± 0.067	2.773AsnThr: 2.773 ± 0.078	2.014AsnVal: 2.014 ± 0.078	0.537AsnTrp: 0.537 ± 0.031	1.462AsnTyr: 1.462 ± 0.052	0.0AsnXaa: 0.0 ± 0.0
Pro	3.138ProAla: 3.138 ± 0.087	0.329ProCys: 0.329 ± 0.026	2.323ProAsp: 2.323 ± 0.069	2.183ProGlu: 2.183 ± 0.082	1.578ProPhe: 1.578 ± 0.06	1.035ProGly: 1.035 ± 0.039	0.861ProHis: 0.861 ± 0.039	3.322ProIle: 3.322 ± 0.082	3.24ProLys: 3.24 ± 0.084	3.719ProLeu: 3.719 ± 0.086	1.188ProMet: 1.188 ± 0.051	2.672ProAsn: 2.672 ± 0.073	1.291ProPro: 1.291 ± 0.057	1.409ProGln: 1.409 ± 0.052	1.257ProArg: 1.257 ± 0.057	2.629ProSer: 2.629 ± 0.079	2.58ProThr: 2.58 ± 0.077	2.604ProVal: 2.604 ± 0.073	0.443ProTrp: 0.443 ± 0.032	1.27ProTyr: 1.27 ± 0.05	0.0ProXaa: 0.0 ± 0.0
Gln	5.226GlnAla: 5.226 ± 0.13	0.303GlnCys: 0.303 ± 0.023	2.345GlnAsp: 2.345 ± 0.071	2.065GlnGlu: 2.065 ± 0.059	1.667GlnPhe: 1.667 ± 0.056	2.982GlnGly: 2.982 ± 0.091	1.077GlnHis: 1.077 ± 0.049	3.482GlnIle: 3.482 ± 0.083	2.866GlnLys: 2.866 ± 0.076	4.386GlnLeu: 4.386 ± 0.094	1.533GlnMet: 1.533 ± 0.05	2.291GlnAsn: 2.291 ± 0.06	1.669GlnPro: 1.669 ± 0.061	1.907GlnGln: 1.907 ± 0.063	1.74GlnArg: 1.74 ± 0.063	3.01GlnSer: 3.01 ± 0.072	3.061GlnThr: 3.061 ± 0.086	3.168GlnVal: 3.168 ± 0.087	0.438GlnTrp: 0.438 ± 0.03	1.244GlnTyr: 1.244 ± 0.059	0.0GlnXaa: 0.0 ± 0.0
Arg	3.48ArgAla: 3.48 ± 0.089	0.417ArgCys: 0.417 ± 0.025	2.065ArgAsp: 2.065 ± 0.076	2.219ArgGlu: 2.219 ± 0.071	2.101ArgPhe: 2.101 ± 0.058	2.377ArgGly: 2.377 ± 0.072	1.548ArgHis: 1.548 ± 0.045	3.162ArgIle: 3.162 ± 0.086	1.693ArgLys: 1.693 ± 0.062	5.476ArgLeu: 5.476 ± 0.11	1.173ArgMet: 1.173 ± 0.043	1.323ArgAsn: 1.323 ± 0.054	1.815ArgPro: 1.815 ± 0.054	2.542ArgGln: 2.542 ± 0.072	2.343ArgArg: 2.343 ± 0.079	2.232ArgSer: 2.232 ± 0.063	2.381ArgThr: 2.381 ± 0.063	2.503ArgVal: 2.503 ± 0.072	0.517ArgTrp: 0.517 ± 0.03	1.836ArgTyr: 1.836 ± 0.056	0.0ArgXaa: 0.0 ± 0.0
Ser	5.015SerAla: 5.015 ± 0.101	0.511SerCys: 0.511 ± 0.033	3.649SerAsp: 3.649 ± 0.085	2.943SerGlu: 2.943 ± 0.073	2.531SerPhe: 2.531 ± 0.073	4.352SerGly: 4.352 ± 0.092	1.9SerHis: 1.9 ± 0.071	3.922SerIle: 3.922 ± 0.071	2.824SerLys: 2.824 ± 0.073	6.413SerLeu: 6.413 ± 0.115	1.627SerMet: 1.627 ± 0.053	2.217SerAsn: 2.217 ± 0.079	2.251SerPro: 2.251 ± 0.071	3.067SerGln: 3.067 ± 0.08	2.492SerArg: 2.492 ± 0.059	3.628SerSer: 3.628 ± 0.082	3.179SerThr: 3.179 ± 0.096	4.136SerVal: 4.136 ± 0.093	0.605SerTrp: 0.605 ± 0.033	1.787SerTyr: 1.787 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	5.688ThrAla: 5.688 ± 0.12	0.485ThrCys: 0.485 ± 0.031	3.702ThrAsp: 3.702 ± 0.088	2.347ThrGlu: 2.347 ± 0.081	1.781ThrPhe: 1.781 ± 0.062	4.198ThrGly: 4.198 ± 0.102	1.9ThrHis: 1.9 ± 0.067	3.69ThrIle: 3.69 ± 0.081	3.332ThrLys: 3.332 ± 0.084	6.545ThrLeu: 6.545 ± 0.095	1.276ThrMet: 1.276 ± 0.042	2.569ThrAsn: 2.569 ± 0.071	3.285ThrPro: 3.285 ± 0.075	3.053ThrGln: 3.053 ± 0.077	2.123ThrArg: 2.123 ± 0.062	2.813ThrSer: 2.813 ± 0.073	3.606ThrThr: 3.606 ± 0.108	3.903ThrVal: 3.903 ± 0.092	0.596ThrTrp: 0.596 ± 0.037	1.483ThrTyr: 1.483 ± 0.061	0.0ThrXaa: 0.0 ± 0.0
Val	6.291ValAla: 6.291 ± 0.118	0.789ValCys: 0.789 ± 0.044	3.589ValAsp: 3.589 ± 0.087	2.967ValGlu: 2.967 ± 0.093	2.634ValPhe: 2.634 ± 0.072	4.773ValGly: 4.773 ± 0.11	1.503ValHis: 1.503 ± 0.053	4.878ValIle: 4.878 ± 0.111	3.074ValLys: 3.074 ± 0.101	6.751ValLeu: 6.751 ± 0.114	2.146ValMet: 2.146 ± 0.066	2.777ValAsn: 2.777 ± 0.073	2.462ValPro: 2.462 ± 0.079	2.512ValGln: 2.512 ± 0.07	3.012ValArg: 3.012 ± 0.065	4.303ValSer: 4.303 ± 0.099	3.296ValThr: 3.296 ± 0.079	4.908ValVal: 4.908 ± 0.119	0.723ValTrp: 0.723 ± 0.037	1.832ValTyr: 1.832 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.919TrpAla: 0.919 ± 0.044	0.132TrpCys: 0.132 ± 0.016	0.487TrpAsp: 0.487 ± 0.03	0.398TrpGlu: 0.398 ± 0.028	0.551TrpPhe: 0.551 ± 0.034	0.691TrpGly: 0.691 ± 0.037	0.402TrpHis: 0.402 ± 0.026	0.74TrpIle: 0.74 ± 0.036	0.289TrpLys: 0.289 ± 0.026	1.772TrpLeu: 1.772 ± 0.067	0.319TrpMet: 0.319 ± 0.028	0.291TrpAsn: 0.291 ± 0.021	0.165TrpPro: 0.165 ± 0.018	1.186TrpGln: 1.186 ± 0.057	0.62TrpArg: 0.62 ± 0.037	0.537TrpSer: 0.537 ± 0.033	0.445TrpThr: 0.445 ± 0.032	0.932TrpVal: 0.932 ± 0.047	0.16TrpTrp: 0.16 ± 0.019	0.4TrpTyr: 0.4 ± 0.031	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.698TyrAla: 2.698 ± 0.062	0.365TyrCys: 0.365 ± 0.023	2.076TyrAsp: 2.076 ± 0.067	1.629TyrGlu: 1.629 ± 0.054	1.471TyrPhe: 1.471 ± 0.051	2.253TyrGly: 2.253 ± 0.069	1.323TyrHis: 1.323 ± 0.052	1.648TyrIle: 1.648 ± 0.058	1.197TyrLys: 1.197 ± 0.05	3.416TyrLeu: 3.416 ± 0.087	0.575TyrMet: 0.575 ± 0.028	1.169TyrAsn: 1.169 ± 0.053	1.379TyrPro: 1.379 ± 0.058	2.155TyrGln: 2.155 ± 0.067	1.695TyrArg: 1.695 ± 0.064	1.484TyrSer: 1.484 ± 0.058	1.627TyrThr: 1.627 ± 0.061	1.768TyrVal: 1.768 ± 0.063	0.376TyrTrp: 0.376 ± 0.028	1.139TyrTyr: 1.139 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1881 proteins (532181 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---