Amino acid dipepetide frequency for Chryseobacterium frigidisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.302AlaAla: 4.302 ± 0.099	0.471AlaCys: 0.471 ± 0.025	3.389AlaAsp: 3.389 ± 0.064	4.416AlaGlu: 4.416 ± 0.08	3.366AlaPhe: 3.366 ± 0.069	4.255AlaGly: 4.255 ± 0.075	0.923AlaHis: 0.923 ± 0.033	4.567AlaIle: 4.567 ± 0.075	5.129AlaLys: 5.129 ± 0.085	5.49AlaLeu: 5.49 ± 0.089	1.49AlaMet: 1.49 ± 0.047	3.417AlaAsn: 3.417 ± 0.075	1.637AlaPro: 1.637 ± 0.048	2.318AlaGln: 2.318 ± 0.05	1.784AlaArg: 1.784 ± 0.055	3.581AlaSer: 3.581 ± 0.079	3.418AlaThr: 3.418 ± 0.076	4.018AlaVal: 4.018 ± 0.082	0.528AlaTrp: 0.528 ± 0.028	2.086AlaTyr: 2.086 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.459CysAla: 0.459 ± 0.02	0.097CysCys: 0.097 ± 0.01	0.43CysAsp: 0.43 ± 0.025	0.51CysGlu: 0.51 ± 0.023	0.416CysPhe: 0.416 ± 0.023	0.647CysGly: 0.647 ± 0.036	0.169CysHis: 0.169 ± 0.015	0.603CysIle: 0.603 ± 0.025	0.501CysLys: 0.501 ± 0.02	0.65CysLeu: 0.65 ± 0.028	0.138CysMet: 0.138 ± 0.012	0.414CysAsn: 0.414 ± 0.023	0.307CysPro: 0.307 ± 0.024	0.191CysGln: 0.191 ± 0.015	0.205CysArg: 0.205 ± 0.016	0.466CysSer: 0.466 ± 0.022	0.364CysThr: 0.364 ± 0.021	0.439CysVal: 0.439 ± 0.021	0.05CysTrp: 0.05 ± 0.007	0.262CysTyr: 0.262 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.387AspAla: 3.387 ± 0.066	0.378AspCys: 0.378 ± 0.02	2.663AspAsp: 2.663 ± 0.062	3.962AspGlu: 3.962 ± 0.071	4.341AspPhe: 4.341 ± 0.07	3.404AspGly: 3.404 ± 0.068	0.852AspHis: 0.852 ± 0.031	3.983AspIle: 3.983 ± 0.073	4.413AspLys: 4.413 ± 0.08	5.922AspLeu: 5.922 ± 0.083	0.914AspMet: 0.914 ± 0.034	2.975AspAsn: 2.975 ± 0.067	1.59AspPro: 1.59 ± 0.045	1.74AspGln: 1.74 ± 0.043	1.655AspArg: 1.655 ± 0.046	3.133AspSer: 3.133 ± 0.059	2.086AspThr: 2.086 ± 0.041	3.354AspVal: 3.354 ± 0.065	0.634AspTrp: 0.634 ± 0.024	2.825AspTyr: 2.825 ± 0.06	0.0AspXaa: 0.0 ± 0.0
Glu	3.623GluAla: 3.623 ± 0.073	0.346GluCys: 0.346 ± 0.02	3.509GluAsp: 3.509 ± 0.067	4.639GluGlu: 4.639 ± 0.105	3.335GluPhe: 3.335 ± 0.066	3.226GluGly: 3.226 ± 0.066	0.882GluHis: 0.882 ± 0.033	6.57GluIle: 6.57 ± 0.095	7.339GluLys: 7.339 ± 0.115	5.415GluLeu: 5.415 ± 0.096	1.752GluMet: 1.752 ± 0.042	6.526GluAsn: 6.526 ± 0.094	1.36GluPro: 1.36 ± 0.038	1.952GluGln: 1.952 ± 0.049	2.139GluArg: 2.139 ± 0.05	3.511GluSer: 3.511 ± 0.065	3.567GluThr: 3.567 ± 0.072	3.958GluVal: 3.958 ± 0.084	0.61GluTrp: 0.61 ± 0.027	2.098GluTyr: 2.098 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	3.629PheAla: 3.629 ± 0.066	0.496PheCys: 0.496 ± 0.026	3.296PheAsp: 3.296 ± 0.062	3.542PheGlu: 3.542 ± 0.062	3.338PhePhe: 3.338 ± 0.087	4.047PheGly: 4.047 ± 0.076	0.961PheHis: 0.961 ± 0.035	4.358PheIle: 4.358 ± 0.091	4.513PheLys: 4.513 ± 0.082	5.85PheLeu: 5.85 ± 0.107	1.175PheMet: 1.175 ± 0.039	3.473PheAsn: 3.473 ± 0.075	2.074PhePro: 2.074 ± 0.048	1.837PheGln: 1.837 ± 0.045	1.814PheArg: 1.814 ± 0.047	4.81PheSer: 4.81 ± 0.081	3.254PheThr: 3.254 ± 0.065	3.231PheVal: 3.231 ± 0.06	0.641PheTrp: 0.641 ± 0.027	2.532PheTyr: 2.532 ± 0.049	0.0PheXaa: 0.0 ± 0.0
Gly	3.839GlyAla: 3.839 ± 0.079	0.543GlyCys: 0.543 ± 0.032	3.139GlyAsp: 3.139 ± 0.056	3.531GlyGlu: 3.531 ± 0.064	3.892GlyPhe: 3.892 ± 0.083	4.541GlyGly: 4.541 ± 0.113	0.941GlyHis: 0.941 ± 0.037	5.396GlyIle: 5.396 ± 0.094	5.77GlyLys: 5.77 ± 0.09	5.399GlyLeu: 5.399 ± 0.082	1.382GlyMet: 1.382 ± 0.039	3.995GlyAsn: 3.995 ± 0.081	1.135GlyPro: 1.135 ± 0.035	1.822GlyGln: 1.822 ± 0.049	1.893GlyArg: 1.893 ± 0.045	3.927GlySer: 3.927 ± 0.074	3.777GlyThr: 3.777 ± 0.078	3.694GlyVal: 3.694 ± 0.068	0.695GlyTrp: 0.695 ± 0.027	2.353GlyTyr: 2.353 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	0.806HisAla: 0.806 ± 0.03	0.15HisCys: 0.15 ± 0.014	0.708HisAsp: 0.708 ± 0.03	0.868HisGlu: 0.868 ± 0.037	1.113HisPhe: 1.113 ± 0.029	0.859HisGly: 0.859 ± 0.034	0.349HisHis: 0.349 ± 0.026	1.11HisIle: 1.11 ± 0.042	1.049HisLys: 1.049 ± 0.033	1.628HisLeu: 1.628 ± 0.047	0.258HisMet: 0.258 ± 0.018	0.814HisAsn: 0.814 ± 0.03	0.751HisPro: 0.751 ± 0.029	0.666HisGln: 0.666 ± 0.028	0.52HisArg: 0.52 ± 0.026	1.019HisSer: 1.019 ± 0.038	0.727HisThr: 0.727 ± 0.029	0.69HisVal: 0.69 ± 0.028	0.19HisTrp: 0.19 ± 0.016	0.74HisTyr: 0.74 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.055IleAla: 5.055 ± 0.084	0.714IleCys: 0.714 ± 0.03	4.569IleAsp: 4.569 ± 0.074	5.082IleGlu: 5.082 ± 0.098	4.849IlePhe: 4.849 ± 0.103	4.734IleGly: 4.734 ± 0.082	1.152IleHis: 1.152 ± 0.035	6.713IleIle: 6.713 ± 0.117	6.481IleLys: 6.481 ± 0.096	8.416IleLeu: 8.416 ± 0.123	1.474IleMet: 1.474 ± 0.04	4.955IleAsn: 4.955 ± 0.083	3.299IlePro: 3.299 ± 0.069	2.432IleGln: 2.432 ± 0.05	2.239IleArg: 2.239 ± 0.058	7.026IleSer: 7.026 ± 0.102	4.427IleThr: 4.427 ± 0.078	4.284IleVal: 4.284 ± 0.074	0.698IleTrp: 0.698 ± 0.03	3.07IleTyr: 3.07 ± 0.063	0.0IleXaa: 0.0 ± 0.0
Lys	4.605LysAla: 4.605 ± 0.074	0.406LysCys: 0.406 ± 0.023	5.087LysAsp: 5.087 ± 0.069	6.204LysGlu: 6.204 ± 0.085	4.263LysPhe: 4.263 ± 0.076	4.322LysGly: 4.322 ± 0.074	1.101LysHis: 1.101 ± 0.038	8.646LysIle: 8.646 ± 0.108	7.988LysLys: 7.988 ± 0.105	7.129LysLeu: 7.129 ± 0.091	2.653LysMet: 2.653 ± 0.062	7.545LysAsn: 7.545 ± 0.107	2.692LysPro: 2.692 ± 0.06	2.385LysGln: 2.385 ± 0.051	2.416LysArg: 2.416 ± 0.056	5.683LysSer: 5.683 ± 0.086	5.212LysThr: 5.212 ± 0.075	4.854LysVal: 4.854 ± 0.087	0.762LysTrp: 0.762 ± 0.031	3.502LysTyr: 3.502 ± 0.068	0.0LysXaa: 0.0 ± 0.0
Leu	5.666LeuAla: 5.666 ± 0.094	0.61LeuCys: 0.61 ± 0.026	4.992LeuAsp: 4.992 ± 0.079	6.34LeuGlu: 6.34 ± 0.111	5.102LeuPhe: 5.102 ± 0.096	5.821LeuGly: 5.821 ± 0.096	1.444LeuHis: 1.444 ± 0.043	7.387LeuIle: 7.387 ± 0.112	9.054LeuLys: 9.054 ± 0.12	8.398LeuLeu: 8.398 ± 0.128	2.116LeuMet: 2.116 ± 0.048	6.337LeuAsn: 6.337 ± 0.086	3.515LeuPro: 3.515 ± 0.07	3.398LeuGln: 3.398 ± 0.059	2.876LeuArg: 2.876 ± 0.054	6.603LeuSer: 6.603 ± 0.1	4.816LeuThr: 4.816 ± 0.08	5.047LeuVal: 5.047 ± 0.083	0.739LeuTrp: 0.739 ± 0.031	3.021LeuTyr: 3.021 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	1.502MetAla: 1.502 ± 0.04	0.137MetCys: 0.137 ± 0.013	1.176MetAsp: 1.176 ± 0.035	1.389MetGlu: 1.389 ± 0.042	0.914MetPhe: 0.914 ± 0.033	1.302MetGly: 1.302 ± 0.039	0.374MetHis: 0.374 ± 0.02	1.779MetIle: 1.779 ± 0.048	2.515MetLys: 2.515 ± 0.055	1.786MetLeu: 1.786 ± 0.051	0.739MetMet: 0.739 ± 0.033	1.366MetAsn: 1.366 ± 0.041	0.848MetPro: 0.848 ± 0.033	0.808MetGln: 0.808 ± 0.031	0.75MetArg: 0.75 ± 0.029	1.425MetSer: 1.425 ± 0.035	1.235MetThr: 1.235 ± 0.039	1.314MetVal: 1.314 ± 0.042	0.17MetTrp: 0.17 ± 0.014	0.571MetTyr: 0.571 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.781AsnAla: 3.781 ± 0.073	0.559AsnCys: 0.559 ± 0.025	3.223AsnAsp: 3.223 ± 0.066	3.928AsnGlu: 3.928 ± 0.065	4.408AsnPhe: 4.408 ± 0.077	4.157AsnGly: 4.157 ± 0.074	1.004AsnHis: 1.004 ± 0.034	5.677AsnIle: 5.677 ± 0.091	4.743AsnLys: 4.743 ± 0.077	7.0AsnLeu: 7.0 ± 0.097	1.252AsnMet: 1.252 ± 0.039	4.165AsnAsn: 4.165 ± 0.092	2.885AsnPro: 2.885 ± 0.05	2.337AsnGln: 2.337 ± 0.065	1.925AsnArg: 1.925 ± 0.046	4.875AsnSer: 4.875 ± 0.092	3.111AsnThr: 3.111 ± 0.069	3.756AsnVal: 3.756 ± 0.067	0.811AsnTrp: 0.811 ± 0.028	3.455AsnTyr: 3.455 ± 0.076	0.0AsnXaa: 0.0 ± 0.0
Pro	1.982ProAla: 1.982 ± 0.062	0.189ProCys: 0.189 ± 0.015	1.896ProAsp: 1.896 ± 0.04	2.913ProGlu: 2.913 ± 0.067	1.974ProPhe: 1.974 ± 0.043	1.75ProGly: 1.75 ± 0.047	0.513ProHis: 0.513 ± 0.026	2.424ProIle: 2.424 ± 0.053	2.808ProLys: 2.808 ± 0.063	2.82ProLeu: 2.82 ± 0.055	0.719ProMet: 0.719 ± 0.033	2.132ProAsn: 2.132 ± 0.052	0.766ProPro: 0.766 ± 0.041	1.208ProGln: 1.208 ± 0.038	0.849ProArg: 0.849 ± 0.032	1.979ProSer: 1.979 ± 0.05	1.969ProThr: 1.969 ± 0.05	2.214ProVal: 2.214 ± 0.051	0.301ProTrp: 0.301 ± 0.02	1.276ProTyr: 1.276 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	1.683GlnAla: 1.683 ± 0.052	0.136GlnCys: 0.136 ± 0.011	1.626GlnAsp: 1.626 ± 0.042	2.093GlnGlu: 2.093 ± 0.054	1.774GlnPhe: 1.774 ± 0.042	1.565GlnGly: 1.565 ± 0.044	0.431GlnHis: 0.431 ± 0.02	3.009GlnIle: 3.009 ± 0.063	3.71GlnLys: 3.71 ± 0.071	2.972GlnLeu: 2.972 ± 0.056	0.796GlnMet: 0.796 ± 0.027	3.072GlnAsn: 3.072 ± 0.07	1.041GlnPro: 1.041 ± 0.041	1.312GlnGln: 1.312 ± 0.05	1.1GlnArg: 1.1 ± 0.035	1.955GlnSer: 1.955 ± 0.048	1.963GlnThr: 1.963 ± 0.052	1.642GlnVal: 1.642 ± 0.042	0.283GlnTrp: 0.283 ± 0.019	1.322GlnTyr: 1.322 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	1.762ArgAla: 1.762 ± 0.051	0.181ArgCys: 0.181 ± 0.014	1.566ArgAsp: 1.566 ± 0.046	2.077ArgGlu: 2.077 ± 0.047	1.752ArgPhe: 1.752 ± 0.044	1.666ArgGly: 1.666 ± 0.049	0.472ArgHis: 0.472 ± 0.023	2.646ArgIle: 2.646 ± 0.051	2.811ArgLys: 2.811 ± 0.064	2.697ArgLeu: 2.697 ± 0.06	0.789ArgMet: 0.789 ± 0.033	2.216ArgAsn: 2.216 ± 0.049	0.95ArgPro: 0.95 ± 0.034	1.027ArgGln: 1.027 ± 0.033	1.145ArgArg: 1.145 ± 0.034	1.686ArgSer: 1.686 ± 0.044	1.61ArgThr: 1.61 ± 0.049	1.77ArgVal: 1.77 ± 0.046	0.276ArgTrp: 0.276 ± 0.017	1.197ArgTyr: 1.197 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.493SerAla: 4.493 ± 0.077	0.646SerCys: 0.646 ± 0.03	3.792SerAsp: 3.792 ± 0.071	4.687SerGlu: 4.687 ± 0.08	3.999SerPhe: 3.999 ± 0.071	4.835SerGly: 4.835 ± 0.084	1.022SerHis: 1.022 ± 0.037	4.865SerIle: 4.865 ± 0.085	5.588SerLys: 5.588 ± 0.079	6.299SerLeu: 6.299 ± 0.106	1.239SerMet: 1.239 ± 0.04	3.727SerAsn: 3.727 ± 0.069	2.187SerPro: 2.187 ± 0.056	2.479SerGln: 2.479 ± 0.055	2.022SerArg: 2.022 ± 0.051	4.378SerSer: 4.378 ± 0.082	3.688SerThr: 3.688 ± 0.073	4.22SerVal: 4.22 ± 0.078	0.698SerTrp: 0.698 ± 0.028	2.553SerTyr: 2.553 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	3.595ThrAla: 3.595 ± 0.075	0.317ThrCys: 0.317 ± 0.019	3.147ThrAsp: 3.147 ± 0.061	3.58ThrGlu: 3.58 ± 0.077	3.177ThrPhe: 3.177 ± 0.072	3.886ThrGly: 3.886 ± 0.094	0.782ThrHis: 0.782 ± 0.026	4.037ThrIle: 4.037 ± 0.079	4.191ThrLys: 4.191 ± 0.071	4.912ThrLeu: 4.912 ± 0.073	0.971ThrMet: 0.971 ± 0.037	3.079ThrAsn: 3.079 ± 0.063	2.065ThrPro: 2.065 ± 0.044	1.768ThrGln: 1.768 ± 0.05	1.397ThrArg: 1.397 ± 0.042	3.755ThrSer: 3.755 ± 0.076	3.096ThrThr: 3.096 ± 0.075	3.461ThrVal: 3.461 ± 0.07	0.492ThrTrp: 0.492 ± 0.023	2.069ThrTyr: 2.069 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	3.77ValAla: 3.77 ± 0.073	0.494ValCys: 0.494 ± 0.02	3.245ValAsp: 3.245 ± 0.057	3.774ValGlu: 3.774 ± 0.075	3.349ValPhe: 3.349 ± 0.066	3.669ValGly: 3.669 ± 0.073	0.785ValHis: 0.785 ± 0.028	4.531ValIle: 4.531 ± 0.076	4.878ValLys: 4.878 ± 0.082	5.564ValLeu: 5.564 ± 0.071	1.303ValMet: 1.303 ± 0.044	3.599ValAsn: 3.599 ± 0.061	2.005ValPro: 2.005 ± 0.052	1.801ValGln: 1.801 ± 0.045	1.8ValArg: 1.8 ± 0.046	4.201ValSer: 4.201 ± 0.074	2.948ValThr: 2.948 ± 0.066	3.425ValVal: 3.425 ± 0.064	0.519ValTrp: 0.519 ± 0.022	2.149ValTyr: 2.149 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	0.551TrpAla: 0.551 ± 0.027	0.086TrpCys: 0.086 ± 0.009	0.569TrpAsp: 0.569 ± 0.025	0.677TrpGlu: 0.677 ± 0.03	0.571TrpPhe: 0.571 ± 0.027	0.565TrpGly: 0.565 ± 0.024	0.166TrpHis: 0.166 ± 0.014	0.725TrpIle: 0.725 ± 0.027	0.891TrpLys: 0.891 ± 0.031	0.936TrpLeu: 0.936 ± 0.036	0.289TrpMet: 0.289 ± 0.018	0.674TrpAsn: 0.674 ± 0.03	0.194TrpPro: 0.194 ± 0.016	0.427TrpGln: 0.427 ± 0.018	0.312TrpArg: 0.312 ± 0.02	0.554TrpSer: 0.554 ± 0.028	0.5TrpThr: 0.5 ± 0.026	0.502TrpVal: 0.502 ± 0.021	0.129TrpTrp: 0.129 ± 0.013	0.356TrpTyr: 0.356 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.096TyrAla: 2.096 ± 0.053	0.36TyrCys: 0.36 ± 0.019	2.187TyrAsp: 2.187 ± 0.049	2.144TyrGlu: 2.144 ± 0.055	2.935TyrPhe: 2.935 ± 0.053	2.412TyrGly: 2.412 ± 0.05	0.691TyrHis: 0.691 ± 0.026	2.645TyrIle: 2.645 ± 0.06	3.084TyrLys: 3.084 ± 0.056	4.001TyrLeu: 4.001 ± 0.074	0.652TyrMet: 0.652 ± 0.026	2.571TyrAsn: 2.571 ± 0.067	1.378TyrPro: 1.378 ± 0.04	1.579TyrGln: 1.579 ± 0.045	1.454TyrArg: 1.454 ± 0.04	2.849TyrSer: 2.849 ± 0.064	2.008TyrThr: 2.008 ± 0.055	1.942TyrVal: 1.942 ± 0.045	0.451TyrTrp: 0.451 ± 0.023	1.839TyrTyr: 1.839 ± 0.053	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2760 proteins (896055 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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