Amino acid dipepetide frequency for Ceratobasidium theobromae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.894AlaAla: 8.894 ± 0.056	1.159AlaCys: 1.159 ± 0.015	4.04AlaAsp: 4.04 ± 0.028	4.788AlaGlu: 4.788 ± 0.042	3.293AlaPhe: 3.293 ± 0.031	5.965AlaGly: 5.965 ± 0.042	2.229AlaHis: 2.229 ± 0.022	4.273AlaIle: 4.273 ± 0.031	3.901AlaLys: 3.901 ± 0.034	8.611AlaLeu: 8.611 ± 0.045	1.838AlaMet: 1.838 ± 0.019	3.07AlaAsn: 3.07 ± 0.025	6.048AlaPro: 6.048 ± 0.054	3.641AlaGln: 3.641 ± 0.027	5.773AlaArg: 5.773 ± 0.036	7.792AlaSer: 7.792 ± 0.055	5.527AlaThr: 5.527 ± 0.038	5.225AlaVal: 5.225 ± 0.038	1.155AlaTrp: 1.155 ± 0.016	2.21AlaTyr: 2.21 ± 0.017	0.0AlaXaa: 0.0 ± 0.0
Cys	1.01CysAla: 1.01 ± 0.015	0.191CysCys: 0.191 ± 0.006	0.683CysAsp: 0.683 ± 0.013	0.6CysGlu: 0.6 ± 0.011	0.469CysPhe: 0.469 ± 0.009	0.912CysGly: 0.912 ± 0.015	0.297CysHis: 0.297 ± 0.007	0.724CysIle: 0.724 ± 0.013	0.498CysLys: 0.498 ± 0.009	1.147CysLeu: 1.147 ± 0.017	0.267CysMet: 0.267 ± 0.007	0.422CysAsn: 0.422 ± 0.009	0.716CysPro: 0.716 ± 0.014	0.418CysGln: 0.418 ± 0.009	0.731CysArg: 0.731 ± 0.012	0.963CysSer: 0.963 ± 0.013	0.873CysThr: 0.873 ± 0.017	0.882CysVal: 0.882 ± 0.015	0.199CysTrp: 0.199 ± 0.006	0.335CysTyr: 0.335 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.734AspAla: 4.734 ± 0.032	0.62AspCys: 0.62 ± 0.012	3.748AspAsp: 3.748 ± 0.036	3.976AspGlu: 3.976 ± 0.036	1.846AspPhe: 1.846 ± 0.021	4.221AspGly: 4.221 ± 0.047	1.232AspHis: 1.232 ± 0.017	3.038AspIle: 3.038 ± 0.027	2.162AspLys: 2.162 ± 0.023	4.741AspLeu: 4.741 ± 0.037	1.18AspMet: 1.18 ± 0.015	1.663AspAsn: 1.663 ± 0.02	3.517AspPro: 3.517 ± 0.03	1.793AspGln: 1.793 ± 0.019	2.906AspArg: 2.906 ± 0.032	4.163AspSer: 4.163 ± 0.032	2.853AspThr: 2.853 ± 0.025	3.568AspVal: 3.568 ± 0.024	0.86AspTrp: 0.86 ± 0.012	1.355AspTyr: 1.355 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.925GluAla: 4.925 ± 0.035	0.71GluCys: 0.71 ± 0.013	3.618GluAsp: 3.618 ± 0.033	4.481GluGlu: 4.481 ± 0.043	1.862GluPhe: 1.862 ± 0.022	3.6GluGly: 3.6 ± 0.029	1.394GluHis: 1.394 ± 0.018	2.826GluIle: 2.826 ± 0.027	2.784GluLys: 2.784 ± 0.032	5.452GluLeu: 5.452 ± 0.047	1.265GluMet: 1.265 ± 0.017	1.852GluAsn: 1.852 ± 0.02	3.046GluPro: 3.046 ± 0.033	2.217GluGln: 2.217 ± 0.023	3.962GluArg: 3.962 ± 0.042	4.094GluSer: 4.094 ± 0.035	2.934GluThr: 2.934 ± 0.026	3.404GluVal: 3.404 ± 0.028	0.942GluTrp: 0.942 ± 0.015	1.511GluTyr: 1.511 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.049PheAla: 3.049 ± 0.028	0.53PheCys: 0.53 ± 0.01	2.079PheAsp: 2.079 ± 0.023	2.076PheGlu: 2.076 ± 0.024	1.408PhePhe: 1.408 ± 0.02	2.789PheGly: 2.789 ± 0.032	0.774PheHis: 0.774 ± 0.011	1.703PheIle: 1.703 ± 0.021	1.487PheLys: 1.487 ± 0.017	2.976PheLeu: 2.976 ± 0.025	0.711PheMet: 0.711 ± 0.011	1.339PheAsn: 1.339 ± 0.015	1.913PhePro: 1.913 ± 0.021	1.229PheGln: 1.229 ± 0.014	1.859PheArg: 1.859 ± 0.017	3.154PheSer: 3.154 ± 0.032	2.069PheThr: 2.069 ± 0.023	2.388PheVal: 2.388 ± 0.023	0.589PheTrp: 0.589 ± 0.011	0.885PheTyr: 0.885 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.756GlyAla: 5.756 ± 0.041	0.851GlyCys: 0.851 ± 0.013	3.43GlyAsp: 3.43 ± 0.027	3.501GlyGlu: 3.501 ± 0.028	2.403GlyPhe: 2.403 ± 0.022	5.727GlyGly: 5.727 ± 0.069	2.058GlyHis: 2.058 ± 0.033	3.281GlyIle: 3.281 ± 0.029	3.207GlyLys: 3.207 ± 0.031	5.944GlyLeu: 5.944 ± 0.036	1.562GlyMet: 1.562 ± 0.023	2.353GlyAsn: 2.353 ± 0.026	3.79GlyPro: 3.79 ± 0.032	2.436GlyGln: 2.436 ± 0.022	4.2GlyArg: 4.2 ± 0.036	6.29GlySer: 6.29 ± 0.047	4.664GlyThr: 4.664 ± 0.034	4.459GlyVal: 4.459 ± 0.033	1.185GlyTrp: 1.185 ± 0.016	1.892GlyTyr: 1.892 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.142HisAla: 2.142 ± 0.021	0.305HisCys: 0.305 ± 0.007	1.29HisAsp: 1.29 ± 0.017	1.276HisGlu: 1.276 ± 0.015	0.869HisPhe: 0.869 ± 0.014	1.647HisGly: 1.647 ± 0.023	0.782HisHis: 0.782 ± 0.017	1.425HisIle: 1.425 ± 0.017	0.902HisLys: 0.902 ± 0.012	2.339HisLeu: 2.339 ± 0.025	0.499HisMet: 0.499 ± 0.01	0.845HisAsn: 0.845 ± 0.012	1.921HisPro: 1.921 ± 0.02	0.869HisGln: 0.869 ± 0.015	1.462HisArg: 1.462 ± 0.019	2.151HisSer: 2.151 ± 0.023	1.83HisThr: 1.83 ± 0.028	1.603HisVal: 1.603 ± 0.018	0.348HisTrp: 0.348 ± 0.009	0.626HisTyr: 0.626 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.486IleAla: 4.486 ± 0.028	0.725IleCys: 0.725 ± 0.013	2.8IleAsp: 2.8 ± 0.024	2.826IleGlu: 2.826 ± 0.029	1.7IlePhe: 1.7 ± 0.022	3.145IleGly: 3.145 ± 0.028	1.248IleHis: 1.248 ± 0.017	2.504IleIle: 2.504 ± 0.023	2.113IleLys: 2.113 ± 0.023	4.296IleLeu: 4.296 ± 0.035	0.993IleMet: 0.993 ± 0.012	1.752IleAsn: 1.752 ± 0.019	3.262IlePro: 3.262 ± 0.024	1.908IleGln: 1.908 ± 0.022	3.095IleArg: 3.095 ± 0.027	4.157IleSer: 4.157 ± 0.034	2.915IleThr: 2.915 ± 0.026	3.371IleVal: 3.371 ± 0.028	0.806IleTrp: 0.806 ± 0.012	1.338IleTyr: 1.338 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.84LysAla: 3.84 ± 0.037	0.494LysCys: 0.494 ± 0.011	2.354LysAsp: 2.354 ± 0.028	2.741LysGlu: 2.741 ± 0.032	1.379LysPhe: 1.379 ± 0.017	2.793LysGly: 2.793 ± 0.028	1.103LysHis: 1.103 ± 0.017	2.013LysIle: 2.013 ± 0.021	2.461LysLys: 2.461 ± 0.034	3.974LysLeu: 3.974 ± 0.032	0.89LysMet: 0.89 ± 0.014	1.527LysAsn: 1.527 ± 0.018	2.686LysPro: 2.686 ± 0.028	1.623LysGln: 1.623 ± 0.018	3.151LysArg: 3.151 ± 0.033	3.445LysSer: 3.445 ± 0.028	2.402LysThr: 2.402 ± 0.026	2.515LysVal: 2.515 ± 0.023	0.612LysTrp: 0.612 ± 0.011	1.211LysTyr: 1.211 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.746LeuAla: 8.746 ± 0.047	1.228LeuCys: 1.228 ± 0.014	5.122LeuAsp: 5.122 ± 0.036	5.455LeuGlu: 5.455 ± 0.039	3.238LeuPhe: 3.238 ± 0.03	6.253LeuGly: 6.253 ± 0.043	2.343LeuHis: 2.343 ± 0.022	3.985LeuIle: 3.985 ± 0.034	4.016LeuLys: 4.016 ± 0.031	7.989LeuLeu: 7.989 ± 0.055	1.648LeuMet: 1.648 ± 0.019	3.142LeuAsn: 3.142 ± 0.028	5.852LeuPro: 5.852 ± 0.042	3.415LeuGln: 3.415 ± 0.028	5.719LeuArg: 5.719 ± 0.04	7.503LeuSer: 7.503 ± 0.039	4.952LeuThr: 4.952 ± 0.031	6.003LeuVal: 6.003 ± 0.036	1.201LeuTrp: 1.201 ± 0.015	2.171LeuTyr: 2.171 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.855MetAla: 1.855 ± 0.021	0.243MetCys: 0.243 ± 0.007	1.124MetAsp: 1.124 ± 0.015	1.118MetGlu: 1.118 ± 0.014	0.743MetPhe: 0.743 ± 0.013	1.358MetGly: 1.358 ± 0.021	0.498MetHis: 0.498 ± 0.01	0.977MetIle: 0.977 ± 0.013	0.847MetLys: 0.847 ± 0.013	1.821MetLeu: 1.821 ± 0.018	0.483MetMet: 0.483 ± 0.011	0.736MetAsn: 0.736 ± 0.012	1.243MetPro: 1.243 ± 0.019	0.739MetGln: 0.739 ± 0.012	1.339MetArg: 1.339 ± 0.016	1.984MetSer: 1.984 ± 0.023	1.172MetThr: 1.172 ± 0.013	1.208MetVal: 1.208 ± 0.015	0.286MetTrp: 0.286 ± 0.008	0.491MetTyr: 0.491 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.134AsnAla: 3.134 ± 0.026	0.388AsnCys: 0.388 ± 0.01	1.781AsnAsp: 1.781 ± 0.019	1.867AsnGlu: 1.867 ± 0.02	1.126AsnPhe: 1.126 ± 0.017	2.66AsnGly: 2.66 ± 0.031	0.795AsnHis: 0.795 ± 0.012	1.991AsnIle: 1.991 ± 0.02	1.447AsnLys: 1.447 ± 0.019	3.271AsnLeu: 3.271 ± 0.029	0.774AsnMet: 0.774 ± 0.013	1.421AsnAsn: 1.421 ± 0.019	2.512AsnPro: 2.512 ± 0.02	1.271AsnGln: 1.271 ± 0.015	1.774AsnArg: 1.774 ± 0.021	2.845AsnSer: 2.845 ± 0.025	2.21AsnThr: 2.21 ± 0.023	2.313AsnVal: 2.313 ± 0.021	0.513AsnTrp: 0.513 ± 0.01	0.932AsnTyr: 0.932 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	6.128ProAla: 6.128 ± 0.052	0.531ProCys: 0.531 ± 0.01	3.765ProAsp: 3.765 ± 0.036	3.8ProGlu: 3.8 ± 0.033	2.237ProPhe: 2.237 ± 0.022	4.229ProGly: 4.229 ± 0.033	1.642ProHis: 1.642 ± 0.019	3.027ProIle: 3.027 ± 0.023	2.705ProLys: 2.705 ± 0.028	5.385ProLeu: 5.385 ± 0.036	1.108ProMet: 1.108 ± 0.018	2.546ProAsn: 2.546 ± 0.026	6.808ProPro: 6.808 ± 0.079	2.469ProGln: 2.469 ± 0.029	3.922ProArg: 3.922 ± 0.039	6.727ProSer: 6.727 ± 0.054	4.896ProThr: 4.896 ± 0.044	3.986ProVal: 3.986 ± 0.033	0.691ProTrp: 0.691 ± 0.012	1.465ProTyr: 1.465 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.447GlnAla: 3.447 ± 0.026	0.455GlnCys: 0.455 ± 0.011	1.841GlnAsp: 1.841 ± 0.02	2.051GlnGlu: 2.051 ± 0.023	1.257GlnPhe: 1.257 ± 0.015	2.339GlnGly: 2.339 ± 0.023	0.985GlnHis: 0.985 ± 0.014	1.814GlnIle: 1.814 ± 0.021	1.499GlnLys: 1.499 ± 0.017	3.753GlnLeu: 3.753 ± 0.03	0.761GlnMet: 0.761 ± 0.012	1.294GlnAsn: 1.294 ± 0.016	2.611GlnPro: 2.611 ± 0.032	1.737GlnGln: 1.737 ± 0.032	2.38GlnArg: 2.38 ± 0.022	3.004GlnSer: 3.004 ± 0.025	2.204GlnThr: 2.204 ± 0.021	2.406GlnVal: 2.406 ± 0.023	0.519GlnTrp: 0.519 ± 0.01	0.989GlnTyr: 0.989 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	5.691ArgAla: 5.691 ± 0.043	0.749ArgCys: 0.749 ± 0.013	3.234ArgAsp: 3.234 ± 0.028	3.657ArgGlu: 3.657 ± 0.036	2.174ArgPhe: 2.174 ± 0.022	3.882ArgGly: 3.882 ± 0.04	1.506ArgHis: 1.506 ± 0.017	3.218ArgIle: 3.218 ± 0.026	2.977ArgLys: 2.977 ± 0.024	5.709ArgLeu: 5.709 ± 0.04	1.32ArgMet: 1.32 ± 0.015	2.054ArgAsn: 2.054 ± 0.021	3.904ArgPro: 3.904 ± 0.033	2.298ArgGln: 2.298 ± 0.023	5.066ArgArg: 5.066 ± 0.044	5.22ArgSer: 5.22 ± 0.048	3.735ArgThr: 3.735 ± 0.03	4.02ArgVal: 4.02 ± 0.031	0.934ArgTrp: 0.934 ± 0.014	1.553ArgTyr: 1.553 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	7.306SerAla: 7.306 ± 0.046	0.933SerCys: 0.933 ± 0.016	4.336SerAsp: 4.336 ± 0.036	4.078SerGlu: 4.078 ± 0.036	2.981SerPhe: 2.981 ± 0.025	6.314SerGly: 6.314 ± 0.046	2.117SerHis: 2.117 ± 0.023	4.042SerIle: 4.042 ± 0.03	3.452SerLys: 3.452 ± 0.032	7.381SerLeu: 7.381 ± 0.042	1.611SerMet: 1.611 ± 0.016	3.047SerAsn: 3.047 ± 0.03	6.92SerPro: 6.92 ± 0.066	3.256SerGln: 3.256 ± 0.027	5.422SerArg: 5.422 ± 0.04	8.996SerSer: 8.996 ± 0.073	6.184SerThr: 6.184 ± 0.044	5.277SerVal: 5.277 ± 0.042	1.039SerTrp: 1.039 ± 0.016	1.985SerTyr: 1.985 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.086ThrAla: 5.086 ± 0.037	0.803ThrCys: 0.803 ± 0.012	2.735ThrAsp: 2.735 ± 0.026	2.788ThrGlu: 2.788 ± 0.026	2.188ThrPhe: 2.188 ± 0.019	4.282ThrGly: 4.282 ± 0.032	1.568ThrHis: 1.568 ± 0.017	3.481ThrIle: 3.481 ± 0.033	2.393ThrLys: 2.393 ± 0.023	5.741ThrLeu: 5.741 ± 0.033	1.181ThrMet: 1.181 ± 0.015	2.187ThrAsn: 2.187 ± 0.022	5.154ThrPro: 5.154 ± 0.047	2.184ThrGln: 2.184 ± 0.024	3.864ThrArg: 3.864 ± 0.032	5.812ThrSer: 5.812 ± 0.045	4.377ThrThr: 4.377 ± 0.04	3.57ThrVal: 3.57 ± 0.026	0.888ThrTrp: 0.888 ± 0.014	1.53ThrTyr: 1.53 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.805ValAla: 5.805 ± 0.041	0.868ValCys: 0.868 ± 0.014	3.562ValAsp: 3.562 ± 0.026	3.686ValGlu: 3.686 ± 0.03	2.301ValPhe: 2.301 ± 0.022	4.13ValGly: 4.13 ± 0.037	1.554ValHis: 1.554 ± 0.019	3.017ValIle: 3.017 ± 0.024	2.707ValLys: 2.707 ± 0.027	5.841ValLeu: 5.841 ± 0.038	1.236ValMet: 1.236 ± 0.014	2.076ValAsn: 2.076 ± 0.024	4.129ValPro: 4.129 ± 0.028	2.452ValGln: 2.452 ± 0.024	3.898ValArg: 3.898 ± 0.033	5.181ValSer: 5.181 ± 0.035	3.54ValThr: 3.54 ± 0.028	4.561ValVal: 4.561 ± 0.037	1.182ValTrp: 1.182 ± 0.021	1.639ValTyr: 1.639 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.231TrpAla: 1.231 ± 0.016	0.224TrpCys: 0.224 ± 0.006	1.06TrpAsp: 1.06 ± 0.019	0.816TrpGlu: 0.816 ± 0.014	0.515TrpPhe: 0.515 ± 0.01	0.944TrpGly: 0.944 ± 0.016	0.358TrpHis: 0.358 ± 0.009	0.714TrpIle: 0.714 ± 0.011	0.679TrpLys: 0.679 ± 0.012	1.241TrpLeu: 1.241 ± 0.019	0.385TrpMet: 0.385 ± 0.008	0.725TrpAsn: 0.725 ± 0.015	0.6TrpPro: 0.6 ± 0.012	0.433TrpGln: 0.433 ± 0.01	0.93TrpArg: 0.93 ± 0.014	1.229TrpSer: 1.229 ± 0.016	0.902TrpThr: 0.902 ± 0.014	0.993TrpVal: 0.993 ± 0.014	0.282TrpTrp: 0.282 ± 0.009	0.395TrpTyr: 0.395 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.168TyrAla: 2.168 ± 0.021	0.33TyrCys: 0.33 ± 0.008	1.576TyrAsp: 1.576 ± 0.019	1.299TyrGlu: 1.299 ± 0.017	1.018TyrPhe: 1.018 ± 0.013	1.798TyrGly: 1.798 ± 0.024	0.65TyrHis: 0.65 ± 0.011	1.389TyrIle: 1.389 ± 0.015	0.977TyrLys: 0.977 ± 0.013	2.366TyrLeu: 2.366 ± 0.022	0.552TyrMet: 0.552 ± 0.01	0.976TyrAsn: 0.976 ± 0.014	1.436TyrPro: 1.436 ± 0.019	0.958TyrGln: 0.958 ± 0.015	1.448TyrArg: 1.448 ± 0.018	1.965TyrSer: 1.965 ± 0.022	1.57TyrThr: 1.57 ± 0.015	1.614TyrVal: 1.614 ± 0.019	0.426TyrTrp: 0.426 ± 0.009	0.784TyrTyr: 0.784 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9256 proteins (5421178 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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