Amino acid dipepetide frequency for Lamium leaf distortion virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.571AlaAla: 2.571 ± 1.141
0.0AlaCys: 0.0 ± 0.0
2.571AlaAsp: 2.571 ± 0.603
4.713AlaGlu: 4.713 ± 0.649
1.714AlaPhe: 1.714 ± 0.971
0.428AlaGly: 0.428 ± 0.332
1.714AlaHis: 1.714 ± 0.861
4.284AlaIle: 4.284 ± 1.644
3.428AlaLys: 3.428 ± 0.895
2.571AlaLeu: 2.571 ± 1.085
1.285AlaMet: 1.285 ± 0.901
1.285AlaAsn: 1.285 ± 1.112
1.285AlaPro: 1.285 ± 0.996
1.714AlaGln: 1.714 ± 0.58
2.142AlaArg: 2.142 ± 1.176
3.428AlaSer: 3.428 ± 1.678
4.284AlaThr: 4.284 ± 1.804
1.714AlaVal: 1.714 ± 0.553
0.428AlaTrp: 0.428 ± 0.371
2.571AlaTyr: 2.571 ± 1.152
0.0AlaXaa: 0.0 ± 0.0
Cys
0.857CysAla: 0.857 ± 0.387
0.857CysCys: 0.857 ± 0.387
0.428CysAsp: 0.428 ± 0.332
2.142CysGlu: 2.142 ± 0.506
0.857CysPhe: 0.857 ± 0.664
0.857CysGly: 0.857 ± 0.592
0.0CysHis: 0.0 ± 0.0
0.428CysIle: 0.428 ± 0.37
1.285CysLys: 1.285 ± 0.632
0.857CysLeu: 0.857 ± 0.343
0.0CysMet: 0.0 ± 0.0
2.142CysAsn: 2.142 ± 1.28
1.714CysPro: 1.714 ± 0.787
0.857CysGln: 0.857 ± 0.387
1.285CysArg: 1.285 ± 0.619
2.571CysSer: 2.571 ± 0.572
0.857CysThr: 0.857 ± 0.55
0.857CysVal: 0.857 ± 0.457
0.428CysTrp: 0.428 ± 0.371
0.428CysTyr: 0.428 ± 0.371
0.0CysXaa: 0.0 ± 0.0
Asp
3.856AspAla: 3.856 ± 1.047
1.714AspCys: 1.714 ± 0.566
2.142AspAsp: 2.142 ± 0.613
3.428AspGlu: 3.428 ± 1.117
3.856AspPhe: 3.856 ± 1.071
0.857AspGly: 0.857 ± 0.592
2.142AspHis: 2.142 ± 0.948
4.284AspIle: 4.284 ± 1.121
4.713AspLys: 4.713 ± 1.0
4.713AspLeu: 4.713 ± 1.062
0.857AspMet: 0.857 ± 0.387
3.428AspAsn: 3.428 ± 1.658
4.284AspPro: 4.284 ± 1.165
0.428AspGln: 0.428 ± 0.332
0.428AspArg: 0.428 ± 0.332
4.284AspSer: 4.284 ± 1.139
2.142AspThr: 2.142 ± 0.747
2.999AspVal: 2.999 ± 0.668
0.0AspTrp: 0.0 ± 0.0
3.428AspTyr: 3.428 ± 0.738
0.0AspXaa: 0.0 ± 0.0
Glu
3.428GluAla: 3.428 ± 1.514
1.285GluCys: 1.285 ± 0.565
4.713GluAsp: 4.713 ± 0.71
10.711GluGlu: 10.711 ± 2.377
3.428GluPhe: 3.428 ± 0.762
2.571GluGly: 2.571 ± 0.954
1.714GluHis: 1.714 ± 0.915
7.284GluIle: 7.284 ± 1.462
7.284GluLys: 7.284 ± 1.367
8.569GluLeu: 8.569 ± 1.228
0.428GluMet: 0.428 ± 0.445
5.141GluAsn: 5.141 ± 1.238
3.428GluPro: 3.428 ± 1.387
3.428GluGln: 3.428 ± 1.591
3.856GluArg: 3.856 ± 0.955
4.713GluSer: 4.713 ± 1.305
2.999GluThr: 2.999 ± 1.83
2.142GluVal: 2.142 ± 0.977
0.428GluTrp: 0.428 ± 0.415
1.714GluTyr: 1.714 ± 0.582
0.0GluXaa: 0.0 ± 0.0
Phe
1.285PheAla: 1.285 ± 0.996
1.285PheCys: 1.285 ± 0.457
2.571PheAsp: 2.571 ± 0.878
2.142PheGlu: 2.142 ± 0.929
2.142PhePhe: 2.142 ± 0.698
1.714PheGly: 1.714 ± 0.545
0.428PheHis: 0.428 ± 0.332
1.714PheIle: 1.714 ± 0.977
3.428PheLys: 3.428 ± 0.662
3.856PheLeu: 3.856 ± 1.857
2.999PheMet: 2.999 ± 0.686
2.142PheAsn: 2.142 ± 0.799
2.142PhePro: 2.142 ± 0.721
2.999PheGln: 2.999 ± 0.503
2.571PheArg: 2.571 ± 0.777
4.713PheSer: 4.713 ± 1.437
2.571PheThr: 2.571 ± 0.987
0.857PheVal: 0.857 ± 0.343
0.857PheTrp: 0.857 ± 0.387
1.285PheTyr: 1.285 ± 0.743
0.0PheXaa: 0.0 ± 0.0
Gly
1.285GlyAla: 1.285 ± 0.807
0.428GlyCys: 0.428 ± 0.371
1.714GlyAsp: 1.714 ± 0.971
4.284GlyGlu: 4.284 ± 1.138
2.999GlyPhe: 2.999 ± 0.503
0.857GlyGly: 0.857 ± 0.568
1.714GlyHis: 1.714 ± 0.582
3.856GlyIle: 3.856 ± 1.071
5.998GlyLys: 5.998 ± 0.169
3.428GlyLeu: 3.428 ± 0.662
0.0GlyMet: 0.0 ± 0.0
3.428GlyAsn: 3.428 ± 1.117
1.285GlyPro: 1.285 ± 1.11
0.0GlyGln: 0.0 ± 0.0
1.285GlyArg: 1.285 ± 0.777
1.285GlySer: 1.285 ± 0.401
2.142GlyThr: 2.142 ± 0.848
2.142GlyVal: 2.142 ± 0.613
0.0GlyTrp: 0.0 ± 0.0
1.285GlyTyr: 1.285 ± 0.682
0.0GlyXaa: 0.0 ± 0.0
His
0.857HisAla: 0.857 ± 0.614
0.428HisCys: 0.428 ± 0.511
0.428HisAsp: 0.428 ± 0.536
1.285HisGlu: 1.285 ± 0.621
0.857HisPhe: 0.857 ± 0.74
0.428HisGly: 0.428 ± 0.37
2.142HisHis: 2.142 ± 1.016
2.999HisIle: 2.999 ± 1.093
2.142HisLys: 2.142 ± 0.634
0.428HisLeu: 0.428 ± 0.415
0.428HisMet: 0.428 ± 0.332
0.428HisAsn: 0.428 ± 0.332
0.857HisPro: 0.857 ± 0.343
1.285HisGln: 1.285 ± 0.806
0.857HisArg: 0.857 ± 0.664
2.571HisSer: 2.571 ± 1.24
0.0HisThr: 0.0 ± 0.0
1.285HisVal: 1.285 ± 0.632
0.428HisTrp: 0.428 ± 0.332
1.714HisTyr: 1.714 ± 0.441
0.0HisXaa: 0.0 ± 0.0
Ile
3.856IleAla: 3.856 ± 1.38
2.999IleCys: 2.999 ± 1.213
6.427IleAsp: 6.427 ± 1.219
6.427IleGlu: 6.427 ± 0.661
3.428IlePhe: 3.428 ± 0.536
3.428IleGly: 3.428 ± 1.036
1.714IleHis: 1.714 ± 0.827
5.57IleIle: 5.57 ± 2.497
6.427IleLys: 6.427 ± 1.896
6.427IleLeu: 6.427 ± 2.068
1.285IleMet: 1.285 ± 0.807
3.428IleAsn: 3.428 ± 1.407
4.713IlePro: 4.713 ± 1.057
2.571IleGln: 2.571 ± 1.209
3.428IleArg: 3.428 ± 1.236
4.284IleSer: 4.284 ± 2.078
3.856IleThr: 3.856 ± 0.692
1.714IleVal: 1.714 ± 0.553
0.857IleTrp: 0.857 ± 0.592
3.856IleTyr: 3.856 ± 1.328
0.0IleXaa: 0.0 ± 0.0
Lys
5.998LysAla: 5.998 ± 0.944
2.571LysCys: 2.571 ± 0.632
8.997LysAsp: 8.997 ± 2.218
7.284LysGlu: 7.284 ± 1.784
5.141LysPhe: 5.141 ± 1.189
4.713LysGly: 4.713 ± 0.465
0.857LysHis: 0.857 ± 0.343
9.426LysIle: 9.426 ± 1.03
16.281LysLys: 16.281 ± 4.439
7.284LysLeu: 7.284 ± 1.579
1.714LysMet: 1.714 ± 0.98
9.426LysAsn: 9.426 ± 2.71
4.284LysPro: 4.284 ± 1.168
4.713LysGln: 4.713 ± 1.119
4.284LysArg: 4.284 ± 1.082
7.712LysSer: 7.712 ± 1.9
3.856LysThr: 3.856 ± 0.349
3.428LysVal: 3.428 ± 0.883
0.428LysTrp: 0.428 ± 0.332
3.856LysTyr: 3.856 ± 1.232
0.0LysXaa: 0.0 ± 0.0
Leu
4.713LeuAla: 4.713 ± 0.923
1.714LeuCys: 1.714 ± 0.484
5.57LeuAsp: 5.57 ± 1.644
8.141LeuGlu: 8.141 ± 0.738
1.285LeuPhe: 1.285 ± 0.565
5.57LeuGly: 5.57 ± 1.569
1.285LeuHis: 1.285 ± 0.457
8.141LeuIle: 8.141 ± 1.007
11.997LeuLys: 11.997 ± 2.157
7.712LeuLeu: 7.712 ± 1.103
0.857LeuMet: 0.857 ± 0.625
4.284LeuAsn: 4.284 ± 1.399
2.142LeuPro: 2.142 ± 1.016
4.284LeuGln: 4.284 ± 0.729
3.428LeuArg: 3.428 ± 0.982
6.855LeuSer: 6.855 ± 1.164
4.284LeuThr: 4.284 ± 2.446
5.141LeuVal: 5.141 ± 1.309
0.0LeuTrp: 0.0 ± 0.0
0.857LeuTyr: 0.857 ± 0.456
0.0LeuXaa: 0.0 ± 0.0
Met
0.428MetAla: 0.428 ± 0.415
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.714MetGlu: 1.714 ± 1.082
1.714MetPhe: 1.714 ± 0.789
0.857MetGly: 0.857 ± 0.74
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.857MetLys: 0.857 ± 0.457
0.857MetLeu: 0.857 ± 0.472
0.0MetMet: 0.0 ± 0.0
2.999MetAsn: 2.999 ± 1.212
0.857MetPro: 0.857 ± 0.74
0.857MetGln: 0.857 ± 0.664
1.285MetArg: 1.285 ± 0.682
1.714MetSer: 1.714 ± 0.524
0.428MetThr: 0.428 ± 0.536
0.428MetVal: 0.428 ± 0.332
0.0MetTrp: 0.0 ± 0.0
1.285MetTyr: 1.285 ± 0.401
0.0MetXaa: 0.0 ± 0.0
Asn
2.999AsnAla: 2.999 ± 0.845
1.285AsnCys: 1.285 ± 0.744
1.285AsnAsp: 1.285 ± 0.688
3.856AsnGlu: 3.856 ± 1.312
2.142AsnPhe: 2.142 ± 0.922
1.285AsnGly: 1.285 ± 0.84
2.142AsnHis: 2.142 ± 0.724
4.284AsnIle: 4.284 ± 0.856
8.569AsnLys: 8.569 ± 2.707
8.997AsnLeu: 8.997 ± 1.718
0.428AsnMet: 0.428 ± 0.332
4.713AsnAsn: 4.713 ± 1.147
3.856AsnPro: 3.856 ± 0.669
2.571AsnGln: 2.571 ± 1.036
2.571AsnArg: 2.571 ± 0.632
2.999AsnSer: 2.999 ± 1.278
3.428AsnThr: 3.428 ± 1.036
5.57AsnVal: 5.57 ± 1.697
0.857AsnTrp: 0.857 ± 0.343
1.285AsnTyr: 1.285 ± 0.996
0.0AsnXaa: 0.0 ± 0.0
Pro
1.285ProAla: 1.285 ± 0.565
1.285ProCys: 1.285 ± 0.623
2.142ProAsp: 2.142 ± 1.182
3.428ProGlu: 3.428 ± 1.254
0.857ProPhe: 0.857 ± 0.387
2.142ProGly: 2.142 ± 0.53
2.571ProHis: 2.571 ± 0.826
1.285ProIle: 1.285 ± 0.302
6.427ProLys: 6.427 ± 1.89
5.998ProLeu: 5.998 ± 1.612
1.285ProMet: 1.285 ± 0.302
3.428ProAsn: 3.428 ± 0.663
0.428ProPro: 0.428 ± 0.371
1.714ProGln: 1.714 ± 1.329
0.857ProArg: 0.857 ± 0.343
5.141ProSer: 5.141 ± 1.581
0.428ProThr: 0.428 ± 0.371
2.142ProVal: 2.142 ± 1.038
0.428ProTrp: 0.428 ± 0.332
0.857ProTyr: 0.857 ± 0.74
0.0ProXaa: 0.0 ± 0.0
Gln
2.571GlnAla: 2.571 ± 0.63
0.0GlnCys: 0.0 ± 0.0
1.714GlnAsp: 1.714 ± 0.582
2.142GlnGlu: 2.142 ± 0.353
1.285GlnPhe: 1.285 ± 0.535
2.571GlnGly: 2.571 ± 0.632
0.0GlnHis: 0.0 ± 0.0
2.142GlnIle: 2.142 ± 0.98
5.141GlnLys: 5.141 ± 1.462
2.999GlnLeu: 2.999 ± 1.068
0.428GlnMet: 0.428 ± 0.37
2.571GlnAsn: 2.571 ± 0.878
1.714GlnPro: 1.714 ± 1.176
2.999GlnGln: 2.999 ± 0.968
1.714GlnArg: 1.714 ± 0.861
4.284GlnSer: 4.284 ± 0.84
1.714GlnThr: 1.714 ± 0.835
2.999GlnVal: 2.999 ± 1.223
0.857GlnTrp: 0.857 ± 0.664
0.857GlnTyr: 0.857 ± 0.343
0.0GlnXaa: 0.0 ± 0.0
Arg
1.285ArgAla: 1.285 ± 0.565
0.428ArgCys: 0.428 ± 0.371
0.857ArgAsp: 0.857 ± 0.343
2.142ArgGlu: 2.142 ± 0.62
1.714ArgPhe: 1.714 ± 0.582
1.285ArgGly: 1.285 ± 0.996
0.428ArgHis: 0.428 ± 0.332
2.999ArgIle: 2.999 ± 0.92
4.284ArgLys: 4.284 ± 1.356
2.999ArgLeu: 2.999 ± 0.85
0.428ArgMet: 0.428 ± 0.332
1.714ArgAsn: 1.714 ± 1.291
1.714ArgPro: 1.714 ± 0.553
0.428ArgGln: 0.428 ± 0.37
2.999ArgArg: 2.999 ± 0.57
2.142ArgSer: 2.142 ± 0.353
2.999ArgThr: 2.999 ± 0.901
2.999ArgVal: 2.999 ± 1.134
1.285ArgTrp: 1.285 ± 0.552
1.714ArgTyr: 1.714 ± 0.915
0.0ArgXaa: 0.0 ± 0.0
Ser
0.857SerAla: 0.857 ± 0.55
0.428SerCys: 0.428 ± 0.37
4.713SerAsp: 4.713 ± 1.01
6.855SerGlu: 6.855 ± 1.686
4.713SerPhe: 4.713 ± 0.721
3.428SerGly: 3.428 ± 1.333
1.714SerHis: 1.714 ± 1.047
6.855SerIle: 6.855 ± 1.883
10.711SerLys: 10.711 ± 1.664
7.712SerLeu: 7.712 ± 1.618
0.857SerMet: 0.857 ± 0.287
3.428SerAsn: 3.428 ± 0.956
1.714SerPro: 1.714 ± 0.441
3.428SerGln: 3.428 ± 1.106
1.714SerArg: 1.714 ± 0.582
12.425SerSer: 12.425 ± 4.243
3.856SerThr: 3.856 ± 1.429
3.856SerVal: 3.856 ± 1.706
0.0SerTrp: 0.0 ± 0.0
2.571SerTyr: 2.571 ± 0.838
0.0SerXaa: 0.0 ± 0.0
Thr
2.999ThrAla: 2.999 ± 1.262
0.428ThrCys: 0.428 ± 0.332
3.856ThrAsp: 3.856 ± 1.132
1.714ThrGlu: 1.714 ± 0.695
0.857ThrPhe: 0.857 ± 0.343
2.142ThrGly: 2.142 ± 0.353
0.857ThrHis: 0.857 ± 0.568
4.284ThrIle: 4.284 ± 1.429
2.999ThrLys: 2.999 ± 0.696
6.855ThrLeu: 6.855 ± 1.657
1.285ThrMet: 1.285 ± 0.632
5.141ThrAsn: 5.141 ± 1.346
1.714ThrPro: 1.714 ± 0.308
1.285ThrGln: 1.285 ± 0.583
0.428ThrArg: 0.428 ± 0.332
4.713ThrSer: 4.713 ± 1.31
3.428ThrThr: 3.428 ± 1.473
0.428ThrVal: 0.428 ± 0.332
0.0ThrTrp: 0.0 ± 0.0
1.285ThrTyr: 1.285 ± 0.401
0.0ThrXaa: 0.0 ± 0.0
Val
0.428ValAla: 0.428 ± 0.332
1.285ValCys: 1.285 ± 0.777
2.142ValAsp: 2.142 ± 0.537
5.141ValGlu: 5.141 ± 0.859
3.856ValPhe: 3.856 ± 0.948
2.571ValGly: 2.571 ± 0.777
0.0ValHis: 0.0 ± 0.0
3.856ValIle: 3.856 ± 1.499
5.57ValLys: 5.57 ± 1.124
2.999ValLeu: 2.999 ± 1.118
0.428ValMet: 0.428 ± 0.37
3.856ValAsn: 3.856 ± 1.271
1.714ValPro: 1.714 ± 0.861
2.571ValGln: 2.571 ± 1.456
1.714ValArg: 1.714 ± 0.582
2.142ValSer: 2.142 ± 1.111
0.857ValThr: 0.857 ± 0.457
2.999ValVal: 2.999 ± 0.772
0.0ValTrp: 0.0 ± 0.0
2.571ValTyr: 2.571 ± 0.567
0.0ValXaa: 0.0 ± 0.0
Trp
0.857TrpAla: 0.857 ± 0.472
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.428TrpGlu: 0.428 ± 0.371
0.0TrpPhe: 0.0 ± 0.0
0.857TrpGly: 0.857 ± 0.343
0.0TrpHis: 0.0 ± 0.0
0.857TrpIle: 0.857 ± 0.387
1.285TrpLys: 1.285 ± 0.777
0.428TrpLeu: 0.428 ± 0.332
0.428TrpMet: 0.428 ± 0.332
1.285TrpAsn: 1.285 ± 0.302
1.285TrpPro: 1.285 ± 0.844
0.857TrpGln: 0.857 ± 0.664
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.714TyrAla: 1.714 ± 0.566
1.285TyrCys: 1.285 ± 0.457
1.714TyrAsp: 1.714 ± 0.835
1.285TyrGlu: 1.285 ± 0.682
0.857TyrPhe: 0.857 ± 0.614
0.857TyrGly: 0.857 ± 0.472
0.428TyrHis: 0.428 ± 0.332
2.142TyrIle: 2.142 ± 0.978
3.428TyrLys: 3.428 ± 0.495
2.571TyrLeu: 2.571 ± 0.803
0.428TyrMet: 0.428 ± 0.371
0.857TyrAsn: 0.857 ± 0.343
2.999TyrPro: 2.999 ± 0.866
1.714TyrGln: 1.714 ± 0.308
0.0TyrArg: 0.0 ± 0.0
4.284TyrSer: 4.284 ± 1.139
2.571TyrThr: 2.571 ± 0.756
2.999TyrVal: 2.999 ± 0.688
1.285TyrTrp: 1.285 ± 0.302
0.428TyrTyr: 0.428 ± 0.37
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2335 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski