Amino acid dipepetide frequency for Aphanomyces stellatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.388AlaAla: 12.388 ± 0.068	1.767AlaCys: 1.767 ± 0.016	4.577AlaAsp: 4.577 ± 0.028	3.708AlaGlu: 3.708 ± 0.025	3.854AlaPhe: 3.854 ± 0.024	4.537AlaGly: 4.537 ± 0.048	2.532AlaHis: 2.532 ± 0.019	4.885AlaIle: 4.885 ± 0.026	4.656AlaLys: 4.656 ± 0.026	9.618AlaLeu: 9.618 ± 0.038	2.978AlaMet: 2.978 ± 0.02	3.319AlaAsn: 3.319 ± 0.022	5.13AlaPro: 5.13 ± 0.036	3.483AlaGln: 3.483 ± 0.023	4.788AlaArg: 4.788 ± 0.027	7.762AlaSer: 7.762 ± 0.038	7.67AlaThr: 7.67 ± 0.04	6.911AlaVal: 6.911 ± 0.033	1.344AlaTrp: 1.344 ± 0.014	2.307AlaTyr: 2.307 ± 0.019	0.002AlaXaa: 0.002 ± 0.0
Cys	1.618CysAla: 1.618 ± 0.017	0.437CysCys: 0.437 ± 0.009	1.049CysAsp: 1.049 ± 0.014	0.691CysGlu: 0.691 ± 0.009	0.805CysPhe: 0.805 ± 0.008	1.33CysGly: 1.33 ± 0.015	0.589CysHis: 0.589 ± 0.007	0.878CysIle: 0.878 ± 0.009	0.697CysLys: 0.697 ± 0.01	1.842CysLeu: 1.842 ± 0.016	0.474CysMet: 0.474 ± 0.007	0.64CysAsn: 0.64 ± 0.01	1.01CysPro: 1.01 ± 0.014	0.686CysGln: 0.686 ± 0.009	1.082CysArg: 1.082 ± 0.012	1.203CysSer: 1.203 ± 0.014	1.281CysThr: 1.281 ± 0.016	1.567CysVal: 1.567 ± 0.014	0.265CysTrp: 0.265 ± 0.006	0.477CysTyr: 0.477 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	6.602AspAla: 6.602 ± 0.034	0.912AspCys: 0.912 ± 0.012	5.756AspAsp: 5.756 ± 0.059	4.148AspGlu: 4.148 ± 0.033	2.079AspPhe: 2.079 ± 0.017	3.906AspGly: 3.906 ± 0.024	1.479AspHis: 1.479 ± 0.014	2.73AspIle: 2.73 ± 0.017	2.385AspLys: 2.385 ± 0.021	4.878AspLeu: 4.878 ± 0.026	1.695AspMet: 1.695 ± 0.015	1.796AspAsn: 1.796 ± 0.015	2.646AspPro: 2.646 ± 0.018	1.752AspGln: 1.752 ± 0.015	2.56AspArg: 2.56 ± 0.021	3.103AspSer: 3.103 ± 0.02	3.184AspThr: 3.184 ± 0.019	5.108AspVal: 5.108 ± 0.025	0.734AspTrp: 0.734 ± 0.011	1.325AspTyr: 1.325 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	4.772GluAla: 4.772 ± 0.029	0.869GluCys: 0.869 ± 0.011	2.893GluAsp: 2.893 ± 0.024	3.129GluGlu: 3.129 ± 0.029	1.871GluPhe: 1.871 ± 0.016	2.431GluGly: 2.431 ± 0.02	1.293GluHis: 1.293 ± 0.015	2.303GluIle: 2.303 ± 0.02	2.668GluLys: 2.668 ± 0.023	4.815GluLeu: 4.815 ± 0.029	1.554GluMet: 1.554 ± 0.014	1.662GluAsn: 1.662 ± 0.015	1.975GluPro: 1.975 ± 0.017	1.707GluGln: 1.707 ± 0.016	2.972GluArg: 2.972 ± 0.026	3.459GluSer: 3.459 ± 0.022	3.171GluThr: 3.171 ± 0.019	3.092GluVal: 3.092 ± 0.024	0.84GluTrp: 0.84 ± 0.009	1.447GluTyr: 1.447 ± 0.012	0.0GluXaa: 0.0 ± 0.0
Phe	3.475PheAla: 3.475 ± 0.021	0.799PheCys: 0.799 ± 0.01	2.619PheAsp: 2.619 ± 0.019	2.082PheGlu: 2.082 ± 0.017	1.622PhePhe: 1.622 ± 0.017	2.817PheGly: 2.817 ± 0.022	1.21PheHis: 1.21 ± 0.012	1.403PheIle: 1.403 ± 0.013	1.521PheLys: 1.521 ± 0.014	3.928PheLeu: 3.928 ± 0.028	0.889PheMet: 0.889 ± 0.01	1.471PheAsn: 1.471 ± 0.013	1.743PhePro: 1.743 ± 0.014	1.706PheGln: 1.706 ± 0.016	1.997PheArg: 1.997 ± 0.015	2.573PheSer: 2.573 ± 0.02	2.059PheThr: 2.059 ± 0.017	3.394PheVal: 3.394 ± 0.022	0.513PheTrp: 0.513 ± 0.009	1.163PheTyr: 1.163 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.036GlyAla: 5.036 ± 0.064	1.279GlyCys: 1.279 ± 0.016	3.419GlyAsp: 3.419 ± 0.021	2.343GlyGlu: 2.343 ± 0.019	2.473GlyPhe: 2.473 ± 0.019	4.837GlyGly: 4.837 ± 0.101	2.009GlyHis: 2.009 ± 0.018	2.651GlyIle: 2.651 ± 0.021	2.543GlyLys: 2.543 ± 0.019	5.252GlyLeu: 5.252 ± 0.024	1.439GlyMet: 1.439 ± 0.014	2.154GlyAsn: 2.154 ± 0.026	2.256GlyPro: 2.256 ± 0.022	2.047GlyGln: 2.047 ± 0.016	3.11GlyArg: 3.11 ± 0.022	4.061GlySer: 4.061 ± 0.044	3.478GlyThr: 3.478 ± 0.046	4.23GlyVal: 4.23 ± 0.029	0.864GlyTrp: 0.864 ± 0.009	1.776GlyTyr: 1.776 ± 0.016	0.001GlyXaa: 0.001 ± 0.0
His	3.25HisAla: 3.25 ± 0.023	0.551HisCys: 0.551 ± 0.008	1.814HisAsp: 1.814 ± 0.018	1.554HisGlu: 1.554 ± 0.013	1.114HisPhe: 1.114 ± 0.011	2.182HisGly: 2.182 ± 0.019	1.248HisHis: 1.248 ± 0.015	1.194HisIle: 1.194 ± 0.012	1.034HisLys: 1.034 ± 0.01	3.007HisLeu: 3.007 ± 0.022	0.808HisMet: 0.808 ± 0.009	0.866HisAsn: 0.866 ± 0.01	1.61HisPro: 1.61 ± 0.015	1.09HisGln: 1.09 ± 0.012	1.908HisArg: 1.908 ± 0.019	1.724HisSer: 1.724 ± 0.015	1.614HisThr: 1.614 ± 0.014	2.892HisVal: 2.892 ± 0.021	0.407HisTrp: 0.407 ± 0.007	0.719HisTyr: 0.719 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.142IleAla: 4.142 ± 0.02	0.79IleCys: 0.79 ± 0.011	2.806IleAsp: 2.806 ± 0.016	2.423IleGlu: 2.423 ± 0.02	1.635IlePhe: 1.635 ± 0.015	2.504IleGly: 2.504 ± 0.02	1.314IleHis: 1.314 ± 0.012	1.416IleIle: 1.416 ± 0.016	1.822IleLys: 1.822 ± 0.015	4.077IleLeu: 4.077 ± 0.025	0.955IleMet: 0.955 ± 0.01	1.453IleAsn: 1.453 ± 0.015	2.242IlePro: 2.242 ± 0.016	2.178IleGln: 2.178 ± 0.017	2.193IleArg: 2.193 ± 0.017	2.706IleSer: 2.706 ± 0.02	2.189IleThr: 2.189 ± 0.022	3.66IleVal: 3.66 ± 0.022	0.513IleTrp: 0.513 ± 0.008	1.214IleTyr: 1.214 ± 0.014	0.001IleXaa: 0.001 ± 0.0
Lys	4.221LysAla: 4.221 ± 0.031	0.836LysCys: 0.836 ± 0.01	2.389LysAsp: 2.389 ± 0.02	2.552LysGlu: 2.552 ± 0.024	1.423LysPhe: 1.423 ± 0.012	2.142LysGly: 2.142 ± 0.018	1.329LysHis: 1.329 ± 0.013	1.76LysIle: 1.76 ± 0.016	3.267LysLys: 3.267 ± 0.037	4.234LysLeu: 4.234 ± 0.027	1.168LysMet: 1.168 ± 0.012	1.452LysAsn: 1.452 ± 0.014	2.317LysPro: 2.317 ± 0.018	2.067LysGln: 2.067 ± 0.016	2.979LysArg: 2.979 ± 0.021	3.091LysSer: 3.091 ± 0.024	2.906LysThr: 2.906 ± 0.02	2.657LysVal: 2.657 ± 0.021	0.671LysTrp: 0.671 ± 0.01	1.363LysTyr: 1.363 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	9.604LeuAla: 9.604 ± 0.036	1.845LeuCys: 1.845 ± 0.015	5.915LeuAsp: 5.915 ± 0.03	5.158LeuGlu: 5.158 ± 0.035	3.811LeuPhe: 3.811 ± 0.026	5.285LeuGly: 5.285 ± 0.026	3.522LeuHis: 3.522 ± 0.028	3.082LeuIle: 3.082 ± 0.022	4.244LeuLys: 4.244 ± 0.027	9.936LeuLeu: 9.936 ± 0.05	2.123LeuMet: 2.123 ± 0.015	3.157LeuAsn: 3.157 ± 0.022	5.209LeuPro: 5.209 ± 0.031	4.531LeuGln: 4.531 ± 0.028	5.636LeuArg: 5.636 ± 0.027	6.854LeuSer: 6.854 ± 0.031	5.675LeuThr: 5.675 ± 0.034	8.075LeuVal: 8.075 ± 0.038	1.345LeuTrp: 1.345 ± 0.013	2.49LeuTyr: 2.49 ± 0.019	0.001LeuXaa: 0.001 ± 0.0
Met	2.71MetAla: 2.71 ± 0.017	0.428MetCys: 0.428 ± 0.007	1.796MetAsp: 1.796 ± 0.016	1.547MetGlu: 1.547 ± 0.015	0.863MetPhe: 0.863 ± 0.01	1.453MetGly: 1.453 ± 0.015	0.825MetHis: 0.825 ± 0.01	0.873MetIle: 0.873 ± 0.011	1.162MetLys: 1.162 ± 0.013	2.555MetLeu: 2.555 ± 0.017	0.699MetMet: 0.699 ± 0.01	0.858MetAsn: 0.858 ± 0.011	1.326MetPro: 1.326 ± 0.012	1.287MetGln: 1.287 ± 0.012	1.428MetArg: 1.428 ± 0.011	1.783MetSer: 1.783 ± 0.013	1.732MetThr: 1.732 ± 0.013	1.683MetVal: 1.683 ± 0.013	0.383MetTrp: 0.383 ± 0.007	0.749MetTyr: 0.749 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.391AsnAla: 3.391 ± 0.021	0.593AsnCys: 0.593 ± 0.01	2.142AsnAsp: 2.142 ± 0.016	1.745AsnGlu: 1.745 ± 0.016	1.208AsnPhe: 1.208 ± 0.012	2.422AsnGly: 2.422 ± 0.022	0.924AsnHis: 0.924 ± 0.012	1.571AsnIle: 1.571 ± 0.016	1.392AsnLys: 1.392 ± 0.014	2.969AsnLeu: 2.969 ± 0.022	0.969AsnMet: 0.969 ± 0.01	1.358AsnAsn: 1.358 ± 0.016	1.892AsnPro: 1.892 ± 0.016	1.45AsnGln: 1.45 ± 0.015	1.594AsnArg: 1.594 ± 0.013	2.034AsnSer: 2.034 ± 0.018	1.959AsnThr: 1.959 ± 0.019	2.844AsnVal: 2.844 ± 0.021	0.47AsnTrp: 0.47 ± 0.007	0.923AsnTyr: 0.923 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	4.688ProAla: 4.688 ± 0.028	0.77ProCys: 0.77 ± 0.013	2.442ProAsp: 2.442 ± 0.018	2.193ProGlu: 2.193 ± 0.017	1.96ProPhe: 1.96 ± 0.016	2.239ProGly: 2.239 ± 0.023	1.558ProHis: 1.558 ± 0.015	2.116ProIle: 2.116 ± 0.017	2.3ProLys: 2.3 ± 0.02	5.045ProLeu: 5.045 ± 0.03	1.273ProMet: 1.273 ± 0.011	1.739ProAsn: 1.739 ± 0.013	4.95ProPro: 4.95 ± 0.048	1.81ProGln: 1.81 ± 0.018	2.94ProArg: 2.94 ± 0.024	5.201ProSer: 5.201 ± 0.031	4.773ProThr: 4.773 ± 0.037	3.462ProVal: 3.462 ± 0.024	0.729ProTrp: 0.729 ± 0.009	1.186ProTyr: 1.186 ± 0.013	0.001ProXaa: 0.001 ± 0.0
Gln	3.697GlnAla: 3.697 ± 0.024	0.82GlnCys: 0.82 ± 0.012	2.028GlnAsp: 2.028 ± 0.014	1.919GlnGlu: 1.919 ± 0.017	1.46GlnPhe: 1.46 ± 0.013	2.076GlnGly: 2.076 ± 0.016	1.401GlnHis: 1.401 ± 0.014	1.514GlnIle: 1.514 ± 0.012	1.664GlnLys: 1.664 ± 0.017	4.288GlnLeu: 4.288 ± 0.026	1.004GlnMet: 1.004 ± 0.011	1.245GlnAsn: 1.245 ± 0.014	2.034GlnPro: 2.034 ± 0.018	1.983GlnGln: 1.983 ± 0.023	2.553GlnArg: 2.553 ± 0.02	2.79GlnSer: 2.79 ± 0.019	2.392GlnThr: 2.392 ± 0.017	2.979GlnVal: 2.979 ± 0.018	0.773GlnTrp: 0.773 ± 0.01	1.208GlnTyr: 1.208 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.728ArgAla: 4.728 ± 0.031	1.07ArgCys: 1.07 ± 0.013	2.926ArgAsp: 2.926 ± 0.02	2.731ArgGlu: 2.731 ± 0.026	2.127ArgPhe: 2.127 ± 0.018	3.139ArgGly: 3.139 ± 0.022	2.07ArgHis: 2.07 ± 0.02	2.297ArgIle: 2.297 ± 0.018	2.528ArgLys: 2.528 ± 0.021	5.496ArgLeu: 5.496 ± 0.029	1.422ArgMet: 1.422 ± 0.014	1.799ArgAsn: 1.799 ± 0.015	2.732ArgPro: 2.732 ± 0.02	2.584ArgGln: 2.584 ± 0.019	4.599ArgArg: 4.599 ± 0.036	3.523ArgSer: 3.523 ± 0.024	3.022ArgThr: 3.022 ± 0.019	4.049ArgVal: 4.049 ± 0.02	0.825ArgTrp: 0.825 ± 0.011	1.363ArgTyr: 1.363 ± 0.012	0.001ArgXaa: 0.001 ± 0.0
Ser	5.955SerAla: 5.955 ± 0.031	1.245SerCys: 1.245 ± 0.014	3.63SerAsp: 3.63 ± 0.022	2.657SerGlu: 2.657 ± 0.021	3.217SerPhe: 3.217 ± 0.021	3.928SerGly: 3.928 ± 0.064	1.945SerHis: 1.945 ± 0.013	3.794SerIle: 3.794 ± 0.024	3.128SerLys: 3.128 ± 0.022	7.065SerLeu: 7.065 ± 0.031	2.028SerMet: 2.028 ± 0.014	2.592SerAsn: 2.592 ± 0.018	4.378SerPro: 4.378 ± 0.031	2.334SerGln: 2.334 ± 0.018	3.406SerArg: 3.406 ± 0.023	7.364SerSer: 7.364 ± 0.048	5.73SerThr: 5.73 ± 0.037	4.992SerVal: 4.992 ± 0.028	1.017SerTrp: 1.017 ± 0.012	1.79SerTyr: 1.79 ± 0.012	0.001SerXaa: 0.001 ± 0.0
Thr	6.097ThrAla: 6.097 ± 0.035	1.285ThrCys: 1.285 ± 0.017	3.16ThrAsp: 3.16 ± 0.022	2.501ThrGlu: 2.501 ± 0.017	2.559ThrPhe: 2.559 ± 0.022	3.145ThrGly: 3.145 ± 0.06	1.826ThrHis: 1.826 ± 0.013	3.1ThrIle: 3.1 ± 0.019	3.225ThrLys: 3.225 ± 0.025	6.484ThrLeu: 6.484 ± 0.034	1.763ThrMet: 1.763 ± 0.013	2.371ThrAsn: 2.371 ± 0.019	4.364ThrPro: 4.364 ± 0.035	2.397ThrGln: 2.397 ± 0.02	3.204ThrArg: 3.204 ± 0.022	5.427ThrSer: 5.427 ± 0.035	6.398ThrThr: 6.398 ± 0.069	4.13ThrVal: 4.13 ± 0.027	1.048ThrTrp: 1.048 ± 0.011	1.692ThrTyr: 1.692 ± 0.015	0.001ThrXaa: 0.001 ± 0.0
Val	8.351ValAla: 8.351 ± 0.042	1.447ValCys: 1.447 ± 0.014	5.069ValAsp: 5.069 ± 0.025	4.035ValGlu: 4.035 ± 0.024	2.952ValPhe: 2.952 ± 0.019	4.361ValGly: 4.361 ± 0.033	2.342ValHis: 2.342 ± 0.018	2.666ValIle: 2.666 ± 0.019	2.858ValLys: 2.858 ± 0.022	7.695ValLeu: 7.695 ± 0.037	1.706ValMet: 1.706 ± 0.013	2.329ValAsn: 2.329 ± 0.018	3.828ValPro: 3.828 ± 0.025	3.24ValGln: 3.24 ± 0.019	3.822ValArg: 3.822 ± 0.021	4.774ValSer: 4.774 ± 0.03	4.201ValThr: 4.201 ± 0.031	7.457ValVal: 7.457 ± 0.041	1.081ValTrp: 1.081 ± 0.012	2.11ValTyr: 2.11 ± 0.018	0.001ValXaa: 0.001 ± 0.0
Trp	1.075TrpAla: 1.075 ± 0.01	0.285TrpCys: 0.285 ± 0.006	0.748TrpAsp: 0.748 ± 0.011	0.566TrpGlu: 0.566 ± 0.008	0.641TrpPhe: 0.641 ± 0.008	0.735TrpGly: 0.735 ± 0.01	0.445TrpHis: 0.445 ± 0.007	0.733TrpIle: 0.733 ± 0.01	0.672TrpLys: 0.672 ± 0.008	1.64TrpLeu: 1.64 ± 0.017	0.414TrpMet: 0.414 ± 0.006	0.57TrpAsn: 0.57 ± 0.008	0.6TrpPro: 0.6 ± 0.01	0.594TrpGln: 0.594 ± 0.01	0.912TrpArg: 0.912 ± 0.012	1.068TrpSer: 1.068 ± 0.012	1.164TrpThr: 1.164 ± 0.013	0.939TrpVal: 0.939 ± 0.012	0.247TrpTrp: 0.247 ± 0.006	0.416TrpTyr: 0.416 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.414TyrAla: 2.414 ± 0.02	0.595TyrCys: 0.595 ± 0.008	1.601TyrAsp: 1.601 ± 0.015	1.24TyrGlu: 1.24 ± 0.011	1.306TyrPhe: 1.306 ± 0.013	1.787TyrGly: 1.787 ± 0.017	0.726TyrHis: 0.726 ± 0.01	1.27TyrIle: 1.27 ± 0.014	1.056TyrLys: 1.056 ± 0.012	2.674TyrLeu: 2.674 ± 0.02	0.78TyrMet: 0.78 ± 0.01	1.022TyrAsn: 1.022 ± 0.012	1.129TyrPro: 1.129 ± 0.012	0.898TyrGln: 0.898 ± 0.009	1.345TyrArg: 1.345 ± 0.012	1.694TyrSer: 1.694 ± 0.015	1.577TyrThr: 1.577 ± 0.015	2.203TyrVal: 2.203 ± 0.017	0.397TyrTrp: 0.397 ± 0.008	0.883TyrTyr: 0.883 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.083XaaXaa: 0.083 ± 0.008

Statistics based on 20738 proteins (9730605 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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