Amino acid dipepetide frequency for Blueberry latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.605AlaAla: 12.605 ± 5.564
2.101AlaCys: 2.101 ± 0.277
6.303AlaAsp: 6.303 ± 2.132
1.401AlaGlu: 1.401 ± 0.682
2.101AlaPhe: 2.101 ± 1.023
9.804AlaGly: 9.804 ± 0.427
0.7AlaHis: 0.7 ± 0.959
7.703AlaIle: 7.703 ± 2.75
4.902AlaLys: 4.902 ± 0.214
7.003AlaLeu: 7.003 ± 0.491
2.801AlaMet: 2.801 ± 1.364
4.202AlaAsn: 4.202 ± 0.554
2.801AlaPro: 2.801 ± 0.064
9.104AlaGln: 9.104 ± 4.669
4.202AlaArg: 4.202 ± 0.554
11.204AlaSer: 11.204 ± 4.946
2.801AlaThr: 2.801 ± 1.236
4.202AlaVal: 4.202 ± 0.554
2.801AlaTrp: 2.801 ± 0.064
4.902AlaTyr: 4.902 ± 0.214
0.0AlaXaa: 0.0 ± 0.0
Cys
0.7CysAla: 0.7 ± 0.341
0.0CysCys: 0.0 ± 0.0
2.101CysAsp: 2.101 ± 0.277
1.401CysGlu: 1.401 ± 0.618
0.7CysPhe: 0.7 ± 0.341
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.7CysIle: 0.7 ± 0.341
2.101CysLys: 2.101 ± 1.023
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.7CysArg: 0.7 ± 0.341
0.7CysSer: 0.7 ± 0.341
0.0CysThr: 0.0 ± 0.0
0.7CysVal: 0.7 ± 0.341
1.401CysTrp: 1.401 ± 0.618
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.501AspAla: 3.501 ± 1.705
2.101AspCys: 2.101 ± 0.277
2.101AspAsp: 2.101 ± 1.023
3.501AspGlu: 3.501 ± 0.405
0.7AspPhe: 0.7 ± 0.341
4.202AspGly: 4.202 ± 2.046
0.7AspHis: 0.7 ± 0.341
4.902AspIle: 4.902 ± 1.514
0.7AspLys: 0.7 ± 0.341
7.703AspLeu: 7.703 ± 1.45
0.7AspMet: 0.7 ± 0.341
1.401AspAsn: 1.401 ± 0.682
2.101AspPro: 2.101 ± 1.577
1.401AspGln: 1.401 ± 0.618
4.202AspArg: 4.202 ± 3.155
4.202AspSer: 4.202 ± 0.554
1.401AspThr: 1.401 ± 0.618
2.101AspVal: 2.101 ± 1.023
2.101AspTrp: 2.101 ± 1.023
3.501AspTyr: 3.501 ± 0.405
0.0AspXaa: 0.0 ± 0.0
Glu
11.204GluAla: 11.204 ± 3.646
0.0GluCys: 0.0 ± 0.0
4.202GluAsp: 4.202 ± 0.746
3.501GluGlu: 3.501 ± 1.705
0.0GluPhe: 0.0 ± 0.0
2.801GluGly: 2.801 ± 1.364
0.0GluHis: 0.0 ± 0.0
2.801GluIle: 2.801 ± 1.364
6.303GluLys: 6.303 ± 0.468
5.602GluLeu: 5.602 ± 1.428
2.801GluMet: 2.801 ± 1.364
4.202GluAsn: 4.202 ± 0.554
0.0GluPro: 0.0 ± 0.0
4.902GluGln: 4.902 ± 0.214
7.003GluArg: 7.003 ± 0.491
1.401GluSer: 1.401 ± 0.618
3.501GluThr: 3.501 ± 2.196
1.401GluVal: 1.401 ± 0.618
0.7GluTrp: 0.7 ± 0.341
0.7GluTyr: 0.7 ± 0.341
0.0GluXaa: 0.0 ± 0.0
Phe
2.101PheAla: 2.101 ± 1.023
0.7PheCys: 0.7 ± 0.341
2.801PheAsp: 2.801 ± 0.064
2.101PheGlu: 2.101 ± 0.277
2.101PhePhe: 2.101 ± 1.023
2.101PheGly: 2.101 ± 1.023
0.7PheHis: 0.7 ± 0.341
1.401PheIle: 1.401 ± 0.682
1.401PheLys: 1.401 ± 0.682
4.202PheLeu: 4.202 ± 0.746
1.401PheMet: 1.401 ± 0.682
1.401PheAsn: 1.401 ± 0.682
0.7PhePro: 0.7 ± 0.341
1.401PheGln: 1.401 ± 0.682
2.801PheArg: 2.801 ± 0.064
3.501PheSer: 3.501 ± 0.405
1.401PheThr: 1.401 ± 0.618
0.7PheVal: 0.7 ± 0.341
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.003GlyAla: 7.003 ± 1.791
0.7GlyCys: 0.7 ± 0.341
3.501GlyAsp: 3.501 ± 0.405
5.602GlyGlu: 5.602 ± 0.127
0.0GlyPhe: 0.0 ± 0.0
6.303GlyGly: 6.303 ± 0.468
0.7GlyHis: 0.7 ± 0.341
7.703GlyIle: 7.703 ± 2.451
2.101GlyLys: 2.101 ± 1.023
4.202GlyLeu: 4.202 ± 2.046
2.101GlyMet: 2.101 ± 0.277
5.602GlyAsn: 5.602 ± 0.127
1.401GlyPro: 1.401 ± 0.618
0.7GlyGln: 0.7 ± 0.341
4.202GlyArg: 4.202 ± 0.554
2.801GlySer: 2.801 ± 0.064
2.101GlyThr: 2.101 ± 1.023
6.303GlyVal: 6.303 ± 0.832
0.7GlyTrp: 0.7 ± 0.341
2.801GlyTyr: 2.801 ± 1.364
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.7HisGlu: 0.7 ± 0.959
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.7HisIle: 0.7 ± 0.341
0.7HisLys: 0.7 ± 0.341
0.7HisLeu: 0.7 ± 0.341
2.101HisMet: 2.101 ± 1.023
0.7HisAsn: 0.7 ± 0.341
0.0HisPro: 0.0 ± 0.0
1.401HisGln: 1.401 ± 0.618
3.501HisArg: 3.501 ± 1.705
0.7HisSer: 0.7 ± 0.341
0.0HisThr: 0.0 ± 0.0
1.401HisVal: 1.401 ± 0.618
0.0HisTrp: 0.0 ± 0.0
1.401HisTyr: 1.401 ± 0.618
0.0HisXaa: 0.0 ± 0.0
Ile
2.101IleAla: 2.101 ± 1.577
0.0IleCys: 0.0 ± 0.0
3.501IleAsp: 3.501 ± 0.405
3.501IleGlu: 3.501 ± 0.895
2.101IlePhe: 2.101 ± 0.277
5.602IleGly: 5.602 ± 2.728
0.7IleHis: 0.7 ± 0.341
5.602IleIle: 5.602 ± 1.428
3.501IleLys: 3.501 ± 0.405
7.003IleLeu: 7.003 ± 0.491
0.7IleMet: 0.7 ± 0.341
2.801IleAsn: 2.801 ± 1.236
4.202IlePro: 4.202 ± 0.746
2.801IleGln: 2.801 ± 1.236
3.501IleArg: 3.501 ± 1.705
6.303IleSer: 6.303 ± 1.769
2.801IleThr: 2.801 ± 1.236
0.7IleVal: 0.7 ± 0.341
0.0IleTrp: 0.0 ± 0.0
0.7IleTyr: 0.7 ± 0.341
0.0IleXaa: 0.0 ± 0.0
Lys
6.303LysAla: 6.303 ± 1.769
0.7LysCys: 0.7 ± 0.341
2.101LysAsp: 2.101 ± 0.277
1.401LysGlu: 1.401 ± 0.682
3.501LysPhe: 3.501 ± 1.705
1.401LysGly: 1.401 ± 0.682
1.401LysHis: 1.401 ± 0.618
4.202LysIle: 4.202 ± 0.554
4.202LysLys: 4.202 ± 0.554
6.303LysLeu: 6.303 ± 1.769
2.101LysMet: 2.101 ± 0.277
1.401LysAsn: 1.401 ± 0.682
2.801LysPro: 2.801 ± 0.064
0.7LysGln: 0.7 ± 0.341
5.602LysArg: 5.602 ± 0.127
2.801LysSer: 2.801 ± 0.064
2.801LysThr: 2.801 ± 1.236
1.401LysVal: 1.401 ± 0.682
1.401LysTrp: 1.401 ± 0.682
1.401LysTyr: 1.401 ± 0.618
0.0LysXaa: 0.0 ± 0.0
Leu
7.703LeuAla: 7.703 ± 0.15
0.7LeuCys: 0.7 ± 0.341
3.501LeuAsp: 3.501 ± 0.405
5.602LeuGlu: 5.602 ± 1.428
3.501LeuPhe: 3.501 ± 0.895
4.202LeuGly: 4.202 ± 0.746
2.801LeuHis: 2.801 ± 1.364
2.101LeuIle: 2.101 ± 1.023
5.602LeuLys: 5.602 ± 0.127
8.403LeuLeu: 8.403 ± 2.792
0.7LeuMet: 0.7 ± 0.341
3.501LeuAsn: 3.501 ± 1.705
4.902LeuPro: 4.902 ± 0.214
2.801LeuGln: 2.801 ± 2.537
8.403LeuArg: 8.403 ± 2.792
6.303LeuSer: 6.303 ± 1.769
10.504LeuThr: 10.504 ± 2.686
4.202LeuVal: 4.202 ± 0.554
1.401LeuTrp: 1.401 ± 0.682
2.801LeuTyr: 2.801 ± 0.064
0.0LeuXaa: 0.0 ± 0.0
Met
2.101MetAla: 2.101 ± 0.277
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
5.602MetGlu: 5.602 ± 1.173
1.401MetPhe: 1.401 ± 0.682
1.401MetGly: 1.401 ± 0.682
0.7MetHis: 0.7 ± 0.341
0.7MetIle: 0.7 ± 0.341
1.401MetLys: 1.401 ± 0.682
0.7MetLeu: 0.7 ± 0.341
1.401MetMet: 1.401 ± 0.682
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.401MetArg: 1.401 ± 0.682
0.7MetSer: 0.7 ± 0.341
2.801MetThr: 2.801 ± 1.236
2.101MetVal: 2.101 ± 1.023
0.7MetTrp: 0.7 ± 0.341
2.101MetTyr: 2.101 ± 1.023
0.0MetXaa: 0.0 ± 0.0
Asn
2.101AsnAla: 2.101 ± 0.277
0.0AsnCys: 0.0 ± 0.0
1.401AsnAsp: 1.401 ± 0.682
0.7AsnGlu: 0.7 ± 0.341
0.7AsnPhe: 0.7 ± 0.341
0.7AsnGly: 0.7 ± 0.341
0.7AsnHis: 0.7 ± 0.341
4.202AsnIle: 4.202 ± 0.554
0.7AsnLys: 0.7 ± 0.341
4.902AsnLeu: 4.902 ± 1.514
1.401AsnMet: 1.401 ± 0.618
0.0AsnAsn: 0.0 ± 0.0
2.101AsnPro: 2.101 ± 1.023
2.101AsnGln: 2.101 ± 0.277
0.0AsnArg: 0.0 ± 0.0
2.101AsnSer: 2.101 ± 0.277
1.401AsnThr: 1.401 ± 0.618
5.602AsnVal: 5.602 ± 0.127
0.0AsnTrp: 0.0 ± 0.0
2.801AsnTyr: 2.801 ± 1.364
0.0AsnXaa: 0.0 ± 0.0
Pro
2.801ProAla: 2.801 ± 0.064
0.0ProCys: 0.0 ± 0.0
2.801ProAsp: 2.801 ± 1.236
2.101ProGlu: 2.101 ± 1.023
2.101ProPhe: 2.101 ± 1.023
0.7ProGly: 0.7 ± 0.341
0.7ProHis: 0.7 ± 0.959
1.401ProIle: 1.401 ± 0.618
2.801ProLys: 2.801 ± 0.064
7.703ProLeu: 7.703 ± 2.451
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
4.902ProPro: 4.902 ± 0.214
1.401ProGln: 1.401 ± 0.682
3.501ProArg: 3.501 ± 0.895
3.501ProSer: 3.501 ± 0.405
2.101ProThr: 2.101 ± 0.277
2.801ProVal: 2.801 ± 1.236
0.7ProTrp: 0.7 ± 0.341
0.7ProTyr: 0.7 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
7.703GlnAla: 7.703 ± 2.75
0.7GlnCys: 0.7 ± 0.341
1.401GlnAsp: 1.401 ± 0.618
4.902GlnGlu: 4.902 ± 1.514
2.101GlnPhe: 2.101 ± 1.023
3.501GlnGly: 3.501 ± 2.196
1.401GlnHis: 1.401 ± 0.618
2.801GlnIle: 2.801 ± 0.064
0.0GlnLys: 0.0 ± 0.0
4.202GlnLeu: 4.202 ± 1.855
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.401GlnPro: 1.401 ± 0.618
5.602GlnGln: 5.602 ± 1.173
2.801GlnArg: 2.801 ± 0.064
2.101GlnSer: 2.101 ± 0.277
3.501GlnThr: 3.501 ± 0.895
4.902GlnVal: 4.902 ± 0.214
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.303ArgAla: 6.303 ± 0.832
0.0ArgCys: 0.0 ± 0.0
5.602ArgAsp: 5.602 ± 1.173
6.303ArgGlu: 6.303 ± 0.468
4.902ArgPhe: 4.902 ± 0.214
4.902ArgGly: 4.902 ± 1.087
0.0ArgHis: 0.0 ± 0.0
0.7ArgIle: 0.7 ± 0.341
6.303ArgLys: 6.303 ± 0.468
8.403ArgLeu: 8.403 ± 0.191
0.0ArgMet: 0.0 ± 0.538
2.101ArgAsn: 2.101 ± 0.277
2.801ArgPro: 2.801 ± 1.364
3.501ArgGln: 3.501 ± 0.405
7.003ArgArg: 7.003 ± 1.791
5.602ArgSer: 5.602 ± 1.428
3.501ArgThr: 3.501 ± 0.405
5.602ArgVal: 5.602 ± 1.173
2.801ArgTrp: 2.801 ± 0.064
1.401ArgTyr: 1.401 ± 0.618
0.0ArgXaa: 0.0 ± 0.0
Ser
8.403SerAla: 8.403 ± 2.409
1.401SerCys: 1.401 ± 0.682
4.202SerAsp: 4.202 ± 0.746
0.7SerGlu: 0.7 ± 0.341
2.801SerPhe: 2.801 ± 0.064
7.003SerGly: 7.003 ± 0.491
1.401SerHis: 1.401 ± 0.682
4.902SerIle: 4.902 ± 1.087
3.501SerLys: 3.501 ± 0.405
5.602SerLeu: 5.602 ± 0.127
3.501SerMet: 3.501 ± 0.343
2.101SerAsn: 2.101 ± 0.277
3.501SerPro: 3.501 ± 1.705
1.401SerGln: 1.401 ± 0.618
4.902SerArg: 4.902 ± 1.087
2.801SerSer: 2.801 ± 0.064
5.602SerThr: 5.602 ± 1.173
2.101SerVal: 2.101 ± 0.277
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.902ThrAla: 4.902 ± 2.814
0.0ThrCys: 0.0 ± 0.0
3.501ThrAsp: 3.501 ± 0.405
5.602ThrGlu: 5.602 ± 2.473
1.401ThrPhe: 1.401 ± 0.682
7.703ThrGly: 7.703 ± 4.05
0.7ThrHis: 0.7 ± 0.341
0.7ThrIle: 0.7 ± 0.341
2.101ThrLys: 2.101 ± 1.023
0.7ThrLeu: 0.7 ± 0.341
1.401ThrMet: 1.401 ± 0.618
1.401ThrAsn: 1.401 ± 0.618
2.801ThrPro: 2.801 ± 1.236
7.003ThrGln: 7.003 ± 1.791
5.602ThrArg: 5.602 ± 2.473
2.101ThrSer: 2.101 ± 1.023
5.602ThrThr: 5.602 ± 2.473
2.801ThrVal: 2.801 ± 0.064
0.0ThrTrp: 0.0 ± 0.0
1.401ThrTyr: 1.401 ± 0.618
0.0ThrXaa: 0.0 ± 0.0
Val
9.104ValAla: 9.104 ± 3.368
0.0ValCys: 0.0 ± 0.0
2.801ValAsp: 2.801 ± 0.064
4.902ValGlu: 4.902 ± 0.214
2.101ValPhe: 2.101 ± 1.023
2.801ValGly: 2.801 ± 1.364
0.7ValHis: 0.7 ± 0.341
3.501ValIle: 3.501 ± 0.895
4.202ValLys: 4.202 ± 1.855
4.902ValLeu: 4.902 ± 1.087
0.7ValMet: 0.7 ± 0.341
2.101ValAsn: 2.101 ± 0.277
3.501ValPro: 3.501 ± 0.405
2.801ValGln: 2.801 ± 0.064
4.902ValArg: 4.902 ± 1.514
3.501ValSer: 3.501 ± 0.405
3.501ValThr: 3.501 ± 0.405
2.801ValVal: 2.801 ± 0.064
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.401TrpAla: 1.401 ± 0.618
0.7TrpCys: 0.7 ± 0.341
0.0TrpAsp: 0.0 ± 0.0
2.101TrpGlu: 2.101 ± 1.023
0.7TrpPhe: 0.7 ± 0.341
0.7TrpGly: 0.7 ± 0.341
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.7TrpLys: 0.7 ± 0.341
0.7TrpLeu: 0.7 ± 0.341
0.7TrpMet: 0.7 ± 0.341
0.7TrpAsn: 0.7 ± 0.341
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.401TrpArg: 1.401 ± 0.682
0.0TrpSer: 0.0 ± 0.0
0.7TrpThr: 0.7 ± 0.341
4.902TrpVal: 4.902 ± 0.214
0.0TrpTrp: 0.0 ± 0.0
0.7TrpTyr: 0.7 ± 0.341
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.602TyrAla: 5.602 ± 1.173
1.401TyrCys: 1.401 ± 0.618
1.401TyrAsp: 1.401 ± 0.682
1.401TyrGlu: 1.401 ± 0.682
0.0TyrPhe: 0.0 ± 0.0
0.7TyrGly: 0.7 ± 0.341
0.0TyrHis: 0.0 ± 0.0
1.401TyrIle: 1.401 ± 0.682
0.7TyrLys: 0.7 ± 0.341
0.7TyrLeu: 0.7 ± 0.341
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.801TyrPro: 2.801 ± 0.064
0.0TyrGln: 0.0 ± 0.0
2.801TyrArg: 2.801 ± 1.364
3.501TyrSer: 3.501 ± 0.405
1.401TyrThr: 1.401 ± 0.618
2.101TyrVal: 2.101 ± 0.277
1.401TyrTrp: 1.401 ± 0.682
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1429 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski