Amino acid dipepetide frequency for Blastochloris tepida

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.346AlaAla: 23.346 ± 0.273	1.243AlaCys: 1.243 ± 0.036	7.841AlaAsp: 7.841 ± 0.1	9.262AlaGlu: 9.262 ± 0.116	4.672AlaPhe: 4.672 ± 0.069	12.606AlaGly: 12.606 ± 0.136	2.355AlaHis: 2.355 ± 0.052	6.361AlaIle: 6.361 ± 0.088	4.376AlaLys: 4.376 ± 0.112	14.937AlaLeu: 14.937 ± 0.161	3.364AlaMet: 3.364 ± 0.055	2.77AlaAsn: 2.77 ± 0.054	7.017AlaPro: 7.017 ± 0.104	3.749AlaGln: 3.749 ± 0.058	10.892AlaArg: 10.892 ± 0.13	6.264AlaSer: 6.264 ± 0.096	6.628AlaThr: 6.628 ± 0.084	10.263AlaVal: 10.263 ± 0.113	1.638AlaTrp: 1.638 ± 0.043	2.379AlaTyr: 2.379 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.977CysAla: 0.977 ± 0.031	0.109CysCys: 0.109 ± 0.011	0.526CysAsp: 0.526 ± 0.02	0.464CysGlu: 0.464 ± 0.023	0.267CysPhe: 0.267 ± 0.016	0.914CysGly: 0.914 ± 0.03	0.256CysHis: 0.256 ± 0.02	0.349CysIle: 0.349 ± 0.02	0.158CysLys: 0.158 ± 0.013	0.765CysLeu: 0.765 ± 0.028	0.149CysMet: 0.149 ± 0.012	0.173CysAsn: 0.173 ± 0.013	0.511CysPro: 0.511 ± 0.027	0.22CysGln: 0.22 ± 0.014	0.783CysArg: 0.783 ± 0.027	0.408CysSer: 0.408 ± 0.024	0.352CysThr: 0.352 ± 0.019	0.599CysVal: 0.599 ± 0.025	0.101CysTrp: 0.101 ± 0.009	0.186CysTyr: 0.186 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.445AspAla: 7.445 ± 0.106	0.496AspCys: 0.496 ± 0.024	3.258AspAsp: 3.258 ± 0.056	3.35AspGlu: 3.35 ± 0.077	1.879AspPhe: 1.879 ± 0.042	5.137AspGly: 5.137 ± 0.083	1.181AspHis: 1.181 ± 0.038	2.932AspIle: 2.932 ± 0.06	1.469AspLys: 1.469 ± 0.045	6.319AspLeu: 6.319 ± 0.085	1.14AspMet: 1.14 ± 0.035	1.075AspAsn: 1.075 ± 0.038	3.722AspPro: 3.722 ± 0.06	1.495AspGln: 1.495 ± 0.038	4.668AspArg: 4.668 ± 0.077	2.028AspSer: 2.028 ± 0.047	2.742AspThr: 2.742 ± 0.067	4.262AspVal: 4.262 ± 0.059	0.926AspTrp: 0.926 ± 0.031	1.256AspTyr: 1.256 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	8.698GluAla: 8.698 ± 0.103	0.337GluCys: 0.337 ± 0.019	2.757GluAsp: 2.757 ± 0.062	2.831GluGlu: 2.831 ± 0.063	1.712GluPhe: 1.712 ± 0.044	4.154GluGly: 4.154 ± 0.064	1.055GluHis: 1.055 ± 0.031	3.279GluIle: 3.279 ± 0.058	1.847GluLys: 1.847 ± 0.05	5.129GluLeu: 5.129 ± 0.074	1.401GluMet: 1.401 ± 0.037	1.239GluAsn: 1.239 ± 0.034	3.32GluPro: 3.32 ± 0.067	1.852GluGln: 1.852 ± 0.045	5.643GluArg: 5.643 ± 0.093	2.329GluSer: 2.329 ± 0.04	3.664GluThr: 3.664 ± 0.056	4.301GluVal: 4.301 ± 0.07	0.607GluTrp: 0.607 ± 0.026	0.84GluTyr: 0.84 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.952PheAla: 4.952 ± 0.079	0.37PheCys: 0.37 ± 0.02	2.51PheAsp: 2.51 ± 0.052	2.166PheGlu: 2.166 ± 0.048	1.219PhePhe: 1.219 ± 0.036	3.57PheGly: 3.57 ± 0.067	0.683PheHis: 0.683 ± 0.023	1.384PheIle: 1.384 ± 0.046	0.928PheLys: 0.928 ± 0.034	3.196PheLeu: 3.196 ± 0.059	0.627PheMet: 0.627 ± 0.026	0.873PheAsn: 0.873 ± 0.034	1.494PhePro: 1.494 ± 0.034	0.885PheGln: 0.885 ± 0.029	2.469PheArg: 2.469 ± 0.054	1.808PheSer: 1.808 ± 0.038	1.749PheThr: 1.749 ± 0.036	2.883PheVal: 2.883 ± 0.053	0.44PheTrp: 0.44 ± 0.022	0.735PheTyr: 0.735 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	10.177GlyAla: 10.177 ± 0.115	0.886GlyCys: 0.886 ± 0.034	4.389GlyAsp: 4.389 ± 0.079	4.871GlyGlu: 4.871 ± 0.073	3.506GlyPhe: 3.506 ± 0.06	7.694GlyGly: 7.694 ± 0.137	1.837GlyHis: 1.837 ± 0.042	4.131GlyIle: 4.131 ± 0.067	2.812GlyLys: 2.812 ± 0.066	9.126GlyLeu: 9.126 ± 0.094	2.012GlyMet: 2.012 ± 0.048	1.798GlyAsn: 1.798 ± 0.063	4.02GlyPro: 4.02 ± 0.073	2.582GlyGln: 2.582 ± 0.049	7.389GlyArg: 7.389 ± 0.103	4.258GlySer: 4.258 ± 0.081	4.813GlyThr: 4.813 ± 0.096	6.248GlyVal: 6.248 ± 0.08	1.406GlyTrp: 1.406 ± 0.035	1.967GlyTyr: 1.967 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.528HisAla: 2.528 ± 0.052	0.194HisCys: 0.194 ± 0.014	1.169HisAsp: 1.169 ± 0.034	0.967HisGlu: 0.967 ± 0.029	0.729HisPhe: 0.729 ± 0.024	1.923HisGly: 1.923 ± 0.048	0.535HisHis: 0.535 ± 0.026	0.827HisIle: 0.827 ± 0.03	0.397HisLys: 0.397 ± 0.02	1.956HisLeu: 1.956 ± 0.047	0.406HisMet: 0.406 ± 0.017	0.357HisAsn: 0.357 ± 0.018	1.35HisPro: 1.35 ± 0.035	0.485HisGln: 0.485 ± 0.021	1.529HisArg: 1.529 ± 0.044	0.708HisSer: 0.708 ± 0.025	0.803HisThr: 0.803 ± 0.027	1.562HisVal: 1.562 ± 0.037	0.306HisTrp: 0.306 ± 0.017	0.48HisTyr: 0.48 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.364IleAla: 7.364 ± 0.089	0.377IleCys: 0.377 ± 0.02	3.52IleAsp: 3.52 ± 0.063	3.589IleGlu: 3.589 ± 0.056	1.193IlePhe: 1.193 ± 0.034	4.621IleGly: 4.621 ± 0.072	0.783IleHis: 0.783 ± 0.026	1.827IleIle: 1.827 ± 0.042	1.315IleLys: 1.315 ± 0.031	3.951IleLeu: 3.951 ± 0.064	0.721IleMet: 0.721 ± 0.027	1.143IleAsn: 1.143 ± 0.036	2.105IlePro: 2.105 ± 0.042	1.053IleGln: 1.053 ± 0.031	3.219IleArg: 3.219 ± 0.05	2.291IleSer: 2.291 ± 0.052	2.412IleThr: 2.412 ± 0.049	4.037IleVal: 4.037 ± 0.071	0.452IleTrp: 0.452 ± 0.019	0.945IleTyr: 0.945 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.176LysAla: 4.176 ± 0.105	0.146LysCys: 0.146 ± 0.011	1.523LysAsp: 1.523 ± 0.045	1.409LysGlu: 1.409 ± 0.05	0.782LysPhe: 0.782 ± 0.028	2.334LysGly: 2.334 ± 0.056	0.485LysHis: 0.485 ± 0.024	1.36LysIle: 1.36 ± 0.036	1.037LysLys: 1.037 ± 0.044	2.951LysLeu: 2.951 ± 0.064	0.642LysMet: 0.642 ± 0.026	0.667LysAsn: 0.667 ± 0.025	2.099LysPro: 2.099 ± 0.061	0.803LysGln: 0.803 ± 0.03	2.338LysArg: 2.338 ± 0.054	1.55LysSer: 1.55 ± 0.043	1.944LysThr: 1.944 ± 0.059	2.383LysVal: 2.383 ± 0.055	0.293LysTrp: 0.293 ± 0.015	0.538LysTyr: 0.538 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	16.236LeuAla: 16.236 ± 0.171	0.73LeuCys: 0.73 ± 0.028	6.617LeuAsp: 6.617 ± 0.089	5.059LeuGlu: 5.059 ± 0.083	3.421LeuPhe: 3.421 ± 0.062	8.43LeuGly: 8.43 ± 0.089	1.866LeuHis: 1.866 ± 0.041	4.679LeuIle: 4.679 ± 0.077	3.486LeuLys: 3.486 ± 0.069	9.019LeuLeu: 9.019 ± 0.128	2.142LeuMet: 2.142 ± 0.048	2.126LeuAsn: 2.126 ± 0.051	5.851LeuPro: 5.851 ± 0.083	2.452LeuGln: 2.452 ± 0.049	7.07LeuArg: 7.07 ± 0.091	5.36LeuSer: 5.36 ± 0.065	5.275LeuThr: 5.275 ± 0.083	8.311LeuVal: 8.311 ± 0.106	1.066LeuTrp: 1.066 ± 0.033	1.903LeuTyr: 1.903 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.951MetAla: 2.951 ± 0.058	0.168MetCys: 0.168 ± 0.012	0.877MetAsp: 0.877 ± 0.026	0.873MetGlu: 0.873 ± 0.033	0.652MetPhe: 0.652 ± 0.024	1.386MetGly: 1.386 ± 0.041	0.37MetHis: 0.37 ± 0.017	1.121MetIle: 1.121 ± 0.032	0.753MetLys: 0.753 ± 0.027	2.244MetLeu: 2.244 ± 0.049	0.593MetMet: 0.593 ± 0.025	0.552MetAsn: 0.552 ± 0.02	1.523MetPro: 1.523 ± 0.038	0.609MetGln: 0.609 ± 0.024	1.719MetArg: 1.719 ± 0.041	1.45MetSer: 1.45 ± 0.033	1.781MetThr: 1.781 ± 0.04	1.708MetVal: 1.708 ± 0.038	0.198MetTrp: 0.198 ± 0.014	0.249MetTyr: 0.249 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.846AsnAla: 2.846 ± 0.064	0.205AsnCys: 0.205 ± 0.015	1.195AsnAsp: 1.195 ± 0.042	1.072AsnGlu: 1.072 ± 0.034	0.725AsnPhe: 0.725 ± 0.027	2.004AsnGly: 2.004 ± 0.045	0.393AsnHis: 0.393 ± 0.019	1.011AsnIle: 1.011 ± 0.035	0.563AsnLys: 0.563 ± 0.027	2.207AsnLeu: 2.207 ± 0.055	0.461AsnMet: 0.461 ± 0.019	0.497AsnAsn: 0.497 ± 0.024	1.621AsnPro: 1.621 ± 0.038	0.551AsnGln: 0.551 ± 0.025	1.695AsnArg: 1.695 ± 0.037	0.956AsnSer: 0.956 ± 0.03	1.05AsnThr: 1.05 ± 0.034	1.703AsnVal: 1.703 ± 0.043	0.355AsnTrp: 0.355 ± 0.019	0.491AsnTyr: 0.491 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	8.709ProAla: 8.709 ± 0.136	0.391ProCys: 0.391 ± 0.019	3.899ProAsp: 3.899 ± 0.066	3.763ProGlu: 3.763 ± 0.06	2.068ProPhe: 2.068 ± 0.051	5.122ProGly: 5.122 ± 0.093	1.124ProHis: 1.124 ± 0.033	2.125ProIle: 2.125 ± 0.048	1.74ProLys: 1.74 ± 0.047	5.014ProLeu: 5.014 ± 0.074	1.137ProMet: 1.137 ± 0.034	1.238ProAsn: 1.238 ± 0.036	3.757ProPro: 3.757 ± 0.107	1.678ProGln: 1.678 ± 0.042	3.674ProArg: 3.674 ± 0.064	2.68ProSer: 2.68 ± 0.053	2.603ProThr: 2.603 ± 0.053	4.61ProVal: 4.61 ± 0.069	0.753ProTrp: 0.753 ± 0.029	1.04ProTyr: 1.04 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.023GlnAla: 4.023 ± 0.068	0.181GlnCys: 0.181 ± 0.014	1.281GlnAsp: 1.281 ± 0.035	1.287GlnGlu: 1.287 ± 0.035	0.897GlnPhe: 0.897 ± 0.031	2.031GlnGly: 2.031 ± 0.047	0.56GlnHis: 0.56 ± 0.023	1.604GlnIle: 1.604 ± 0.041	0.764GlnLys: 0.764 ± 0.027	2.453GlnLeu: 2.453 ± 0.054	0.696GlnMet: 0.696 ± 0.025	0.614GlnAsn: 0.614 ± 0.028	1.815GlnPro: 1.815 ± 0.05	0.968GlnGln: 0.968 ± 0.036	2.523GlnArg: 2.523 ± 0.054	1.446GlnSer: 1.446 ± 0.041	1.633GlnThr: 1.633 ± 0.042	2.181GlnVal: 2.181 ± 0.051	0.316GlnTrp: 0.316 ± 0.019	0.459GlnTyr: 0.459 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	10.006ArgAla: 10.006 ± 0.127	0.58ArgCys: 0.58 ± 0.024	4.278ArgAsp: 4.278 ± 0.07	4.433ArgGlu: 4.433 ± 0.075	3.228ArgPhe: 3.228 ± 0.058	5.428ArgGly: 5.428 ± 0.084	1.832ArgHis: 1.832 ± 0.042	4.172ArgIle: 4.172 ± 0.062	2.09ArgLys: 2.09 ± 0.055	9.531ArgLeu: 9.531 ± 0.12	1.799ArgMet: 1.799 ± 0.041	1.715ArgAsn: 1.715 ± 0.033	4.647ArgPro: 4.647 ± 0.098	2.533ArgGln: 2.533 ± 0.052	7.374ArgArg: 7.374 ± 0.124	3.479ArgSer: 3.479 ± 0.062	4.009ArgThr: 4.009 ± 0.064	5.423ArgVal: 5.423 ± 0.062	1.068ArgTrp: 1.068 ± 0.035	1.59ArgTyr: 1.59 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.152SerAla: 6.152 ± 0.089	0.394SerCys: 0.394 ± 0.021	2.606SerAsp: 2.606 ± 0.054	2.576SerGlu: 2.576 ± 0.056	1.935SerPhe: 1.935 ± 0.05	4.996SerGly: 4.996 ± 0.079	0.902SerHis: 0.902 ± 0.029	2.202SerIle: 2.202 ± 0.052	1.316SerLys: 1.316 ± 0.044	4.743SerLeu: 4.743 ± 0.071	0.994SerMet: 0.994 ± 0.028	1.095SerAsn: 1.095 ± 0.034	2.772SerPro: 2.772 ± 0.042	1.371SerGln: 1.371 ± 0.041	3.577SerArg: 3.577 ± 0.066	2.472SerSer: 2.472 ± 0.064	2.496SerThr: 2.496 ± 0.064	3.577SerVal: 3.577 ± 0.059	0.607SerTrp: 0.607 ± 0.024	1.042SerTyr: 1.042 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	6.905ThrAla: 6.905 ± 0.095	0.442ThrCys: 0.442 ± 0.021	2.661ThrAsp: 2.661 ± 0.052	2.566ThrGlu: 2.566 ± 0.044	2.012ThrPhe: 2.012 ± 0.042	5.124ThrGly: 5.124 ± 0.082	0.942ThrHis: 0.942 ± 0.031	2.622ThrIle: 2.622 ± 0.053	1.388ThrLys: 1.388 ± 0.043	5.997ThrLeu: 5.997 ± 0.091	1.044ThrMet: 1.044 ± 0.031	1.181ThrAsn: 1.181 ± 0.035	3.391ThrPro: 3.391 ± 0.056	1.274ThrGln: 1.274 ± 0.037	3.644ThrArg: 3.644 ± 0.062	2.507ThrSer: 2.507 ± 0.053	2.81ThrThr: 2.81 ± 0.067	4.685ThrVal: 4.685 ± 0.08	0.607ThrTrp: 0.607 ± 0.021	1.071ThrTyr: 1.071 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	10.846ValAla: 10.846 ± 0.107	0.675ValCys: 0.675 ± 0.029	4.043ValAsp: 4.043 ± 0.061	4.922ValGlu: 4.922 ± 0.076	2.832ValPhe: 2.832 ± 0.056	5.684ValGly: 5.684 ± 0.075	1.392ValHis: 1.392 ± 0.031	3.664ValIle: 3.664 ± 0.069	2.252ValLys: 2.252 ± 0.053	8.028ValLeu: 8.028 ± 0.099	1.769ValMet: 1.769 ± 0.038	1.684ValAsn: 1.684 ± 0.044	4.443ValPro: 4.443 ± 0.074	2.037ValGln: 2.037 ± 0.047	5.968ValArg: 5.968 ± 0.078	4.136ValSer: 4.136 ± 0.074	4.414ValThr: 4.414 ± 0.078	7.146ValVal: 7.146 ± 0.101	0.947ValTrp: 0.947 ± 0.028	1.43ValTyr: 1.43 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.258TrpAla: 1.258 ± 0.034	0.138TrpCys: 0.138 ± 0.012	0.542TrpAsp: 0.542 ± 0.021	0.51TrpGlu: 0.51 ± 0.021	0.478TrpPhe: 0.478 ± 0.023	0.888TrpGly: 0.888 ± 0.03	0.305TrpHis: 0.305 ± 0.017	0.552TrpIle: 0.552 ± 0.022	0.324TrpLys: 0.324 ± 0.018	1.582TrpLeu: 1.582 ± 0.039	0.312TrpMet: 0.312 ± 0.017	0.344TrpAsn: 0.344 ± 0.016	0.736TrpPro: 0.736 ± 0.026	0.526TrpGln: 0.526 ± 0.024	1.291TrpArg: 1.291 ± 0.038	0.733TrpSer: 0.733 ± 0.028	0.773TrpThr: 0.773 ± 0.031	0.858TrpVal: 0.858 ± 0.025	0.249TrpTrp: 0.249 ± 0.018	0.243TrpTyr: 0.243 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.369TyrAla: 2.369 ± 0.049	0.206TyrCys: 0.206 ± 0.013	1.287TyrAsp: 1.287 ± 0.042	1.025TyrGlu: 1.025 ± 0.031	0.732TyrPhe: 0.732 ± 0.028	1.874TyrGly: 1.874 ± 0.046	0.357TyrHis: 0.357 ± 0.018	0.716TyrIle: 0.716 ± 0.027	0.445TyrLys: 0.445 ± 0.022	1.951TyrLeu: 1.951 ± 0.044	0.371TyrMet: 0.371 ± 0.021	0.459TyrAsn: 0.459 ± 0.02	0.93TyrPro: 0.93 ± 0.03	0.61TyrGln: 0.61 ± 0.026	1.748TyrArg: 1.748 ± 0.043	0.963TyrSer: 0.963 ± 0.031	0.922TyrThr: 0.922 ± 0.029	1.574TyrVal: 1.574 ± 0.034	0.306TyrTrp: 0.306 ± 0.016	0.495TyrTyr: 0.495 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3554 proteins (1106585 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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