Amino acid dipepetide frequency for secondary endosymbiont of Ctenarytaina eucalypti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.944AlaAla: 7.944 ± 0.224
1.355AlaCys: 1.355 ± 0.082
4.025AlaAsp: 4.025 ± 0.133
4.966AlaGlu: 4.966 ± 0.179
3.052AlaPhe: 3.052 ± 0.111
6.141AlaGly: 6.141 ± 0.169
2.054AlaHis: 2.054 ± 0.1
6.071AlaIle: 6.071 ± 0.171
3.89AlaLys: 3.89 ± 0.141
11.181AlaLeu: 11.181 ± 0.236
2.506AlaMet: 2.506 ± 0.099
2.608AlaAsn: 2.608 ± 0.107
2.867AlaPro: 2.867 ± 0.12
3.344AlaGln: 3.344 ± 0.104
5.648AlaArg: 5.648 ± 0.174
5.286AlaSer: 5.286 ± 0.137
3.927AlaThr: 3.927 ± 0.119
5.931AlaVal: 5.931 ± 0.161
1.117AlaTrp: 1.117 ± 0.077
2.465AlaTyr: 2.465 ± 0.106
0.0AlaXaa: 0.0 ± 0.0
Cys
1.167CysAla: 1.167 ± 0.059
0.283CysCys: 0.283 ± 0.036
0.764CysAsp: 0.764 ± 0.063
0.62CysGlu: 0.62 ± 0.058
0.653CysPhe: 0.653 ± 0.051
1.105CysGly: 1.105 ± 0.077
0.411CysHis: 0.411 ± 0.045
0.912CysIle: 0.912 ± 0.075
0.522CysLys: 0.522 ± 0.046
1.372CysLeu: 1.372 ± 0.087
0.435CysMet: 0.435 ± 0.04
0.513CysAsn: 0.513 ± 0.047
0.604CysPro: 0.604 ± 0.054
0.55CysGln: 0.55 ± 0.051
0.887CysArg: 0.887 ± 0.057
0.953CysSer: 0.953 ± 0.063
0.637CysThr: 0.637 ± 0.05
0.858CysVal: 0.858 ± 0.069
0.205CysTrp: 0.205 ± 0.026
0.497CysTyr: 0.497 ± 0.051
0.0CysXaa: 0.0 ± 0.0
Asp
4.715AspAla: 4.715 ± 0.15
0.678AspCys: 0.678 ± 0.058
2.374AspAsp: 2.374 ± 0.099
2.736AspGlu: 2.736 ± 0.122
2.013AspPhe: 2.013 ± 0.09
3.233AspGly: 3.233 ± 0.123
1.261AspHis: 1.261 ± 0.071
3.709AspIle: 3.709 ± 0.128
2.128AspLys: 2.128 ± 0.11
4.715AspLeu: 4.715 ± 0.144
1.446AspMet: 1.446 ± 0.078
1.852AspAsn: 1.852 ± 0.093
1.976AspPro: 1.976 ± 0.086
1.807AspGln: 1.807 ± 0.08
3.167AspArg: 3.167 ± 0.141
2.797AspSer: 2.797 ± 0.102
2.522AspThr: 2.522 ± 0.113
3.635AspVal: 3.635 ± 0.141
0.645AspTrp: 0.645 ± 0.055
1.725AspTyr: 1.725 ± 0.088
0.0AspXaa: 0.0 ± 0.0
Glu
4.995GluAla: 4.995 ± 0.181
0.608GluCys: 0.608 ± 0.047
2.452GluAsp: 2.452 ± 0.095
3.483GluGlu: 3.483 ± 0.139
1.59GluPhe: 1.59 ± 0.091
3.233GluGly: 3.233 ± 0.125
1.643GluHis: 1.643 ± 0.082
3.783GluIle: 3.783 ± 0.117
3.454GluLys: 3.454 ± 0.145
5.381GluLeu: 5.381 ± 0.145
1.618GluMet: 1.618 ± 0.089
2.337GluAsn: 2.337 ± 0.093
1.774GluPro: 1.774 ± 0.087
2.584GluGln: 2.584 ± 0.109
4.116GluArg: 4.116 ± 0.148
2.81GluSer: 2.81 ± 0.108
2.506GluThr: 2.506 ± 0.105
4.054GluVal: 4.054 ± 0.143
0.509GluTrp: 0.509 ± 0.043
1.487GluTyr: 1.487 ± 0.072
0.0GluXaa: 0.0 ± 0.0
Phe
2.506PheAla: 2.506 ± 0.109
0.661PheCys: 0.661 ± 0.052
2.062PheAsp: 2.062 ± 0.089
1.844PheGlu: 1.844 ± 0.091
1.943PhePhe: 1.943 ± 0.103
2.674PheGly: 2.674 ± 0.107
0.883PheHis: 0.883 ± 0.064
2.867PheIle: 2.867 ± 0.11
1.388PheLys: 1.388 ± 0.078
4.021PheLeu: 4.021 ± 0.144
1.15PheMet: 1.15 ± 0.065
1.766PheAsn: 1.766 ± 0.081
1.602PhePro: 1.602 ± 0.073
1.273PheGln: 1.273 ± 0.072
2.132PheArg: 2.132 ± 0.097
3.569PheSer: 3.569 ± 0.106
1.996PheThr: 1.996 ± 0.093
2.095PheVal: 2.095 ± 0.111
0.431PheTrp: 0.431 ± 0.04
1.269PheTyr: 1.269 ± 0.076
0.0PheXaa: 0.0 ± 0.0
Gly
5.405GlyAla: 5.405 ± 0.166
1.113GlyCys: 1.113 ± 0.06
3.372GlyAsp: 3.372 ± 0.133
3.906GlyGlu: 3.906 ± 0.143
2.785GlyPhe: 2.785 ± 0.116
4.839GlyGly: 4.839 ± 0.162
2.07GlyHis: 2.07 ± 0.1
5.212GlyIle: 5.212 ± 0.162
4.058GlyLys: 4.058 ± 0.131
6.942GlyLeu: 6.942 ± 0.192
2.132GlyMet: 2.132 ± 0.103
2.456GlyAsn: 2.456 ± 0.107
1.881GlyPro: 1.881 ± 0.095
2.543GlyGln: 2.543 ± 0.111
4.44GlyArg: 4.44 ± 0.126
3.869GlySer: 3.869 ± 0.117
3.417GlyThr: 3.417 ± 0.105
5.065GlyVal: 5.065 ± 0.149
0.854GlyTrp: 0.854 ± 0.067
2.21GlyTyr: 2.21 ± 0.101
0.0GlyXaa: 0.0 ± 0.0
His
2.14HisAla: 2.14 ± 0.091
0.481HisCys: 0.481 ± 0.045
1.245HisAsp: 1.245 ± 0.076
1.236HisGlu: 1.236 ± 0.065
1.29HisPhe: 1.29 ± 0.081
1.947HisGly: 1.947 ± 0.089
0.912HisHis: 0.912 ± 0.073
1.668HisIle: 1.668 ± 0.082
0.949HisLys: 0.949 ± 0.062
2.982HisLeu: 2.982 ± 0.114
0.711HisMet: 0.711 ± 0.054
1.138HisAsn: 1.138 ± 0.059
1.536HisPro: 1.536 ± 0.076
1.269HisGln: 1.269 ± 0.079
1.631HisArg: 1.631 ± 0.078
1.512HisSer: 1.512 ± 0.084
1.319HisThr: 1.319 ± 0.076
1.746HisVal: 1.746 ± 0.093
0.398HisTrp: 0.398 ± 0.04
1.15HisTyr: 1.15 ± 0.069
0.0HisXaa: 0.0 ± 0.0
Ile
6.617IleAla: 6.617 ± 0.19
0.887IleCys: 0.887 ± 0.066
4.062IleAsp: 4.062 ± 0.135
3.845IleGlu: 3.845 ± 0.161
2.666IlePhe: 2.666 ± 0.115
5.184IleGly: 5.184 ± 0.165
1.577IleHis: 1.577 ± 0.069
4.588IleIle: 4.588 ± 0.163
3.196IleLys: 3.196 ± 0.122
6.219IleLeu: 6.219 ± 0.168
1.68IleMet: 1.68 ± 0.092
3.138IleAsn: 3.138 ± 0.1
2.666IlePro: 2.666 ± 0.106
2.202IleGln: 2.202 ± 0.103
3.914IleArg: 3.914 ± 0.113
4.551IleSer: 4.551 ± 0.128
4.054IleThr: 4.054 ± 0.131
4.37IleVal: 4.37 ± 0.14
0.628IleTrp: 0.628 ± 0.053
1.799IleTyr: 1.799 ± 0.085
0.0IleXaa: 0.0 ± 0.0
Lys
4.165LysAla: 4.165 ± 0.127
0.485LysCys: 0.485 ± 0.051
2.119LysAsp: 2.119 ± 0.101
2.744LysGlu: 2.744 ± 0.121
1.314LysPhe: 1.314 ± 0.076
2.925LysGly: 2.925 ± 0.13
1.162LysHis: 1.162 ± 0.069
3.356LysIle: 3.356 ± 0.124
3.348LysLys: 3.348 ± 0.117
4.453LysLeu: 4.453 ± 0.111
1.544LysMet: 1.544 ± 0.094
2.185LysAsn: 2.185 ± 0.094
1.852LysPro: 1.852 ± 0.088
1.959LysGln: 1.959 ± 0.087
3.27LysArg: 3.27 ± 0.114
2.731LysSer: 2.731 ± 0.101
2.879LysThr: 2.879 ± 0.11
3.504LysVal: 3.504 ± 0.134
0.452LysTrp: 0.452 ± 0.041
1.282LysTyr: 1.282 ± 0.072
0.0LysXaa: 0.0 ± 0.0
Leu
9.718LeuAla: 9.718 ± 0.229
1.54LeuCys: 1.54 ± 0.078
5.545LeuAsp: 5.545 ± 0.173
5.886LeuGlu: 5.886 ± 0.195
4.034LeuPhe: 4.034 ± 0.14
7.053LeuGly: 7.053 ± 0.18
3.011LeuHis: 3.011 ± 0.109
6.519LeuIle: 6.519 ± 0.173
5.073LeuLys: 5.073 ± 0.124
12.088LeuLeu: 12.088 ± 0.3
3.196LeuMet: 3.196 ± 0.121
4.157LeuAsn: 4.157 ± 0.132
5.422LeuPro: 5.422 ± 0.18
4.186LeuGln: 4.186 ± 0.153
6.814LeuArg: 6.814 ± 0.18
8.158LeuSer: 8.158 ± 0.18
6.297LeuThr: 6.297 ± 0.156
7.077LeuVal: 7.077 ± 0.186
1.171LeuTrp: 1.171 ± 0.082
3.04LeuTyr: 3.04 ± 0.123
0.0LeuXaa: 0.0 ± 0.0
Met
2.403MetAla: 2.403 ± 0.091
0.251MetCys: 0.251 ± 0.034
0.99MetAsp: 0.99 ± 0.066
1.121MetGlu: 1.121 ± 0.07
0.838MetPhe: 0.838 ± 0.063
1.709MetGly: 1.709 ± 0.086
0.879MetHis: 0.879 ± 0.062
1.935MetIle: 1.935 ± 0.087
1.438MetLys: 1.438 ± 0.069
3.771MetLeu: 3.771 ± 0.121
0.941MetMet: 0.941 ± 0.068
1.097MetAsn: 1.097 ± 0.067
1.553MetPro: 1.553 ± 0.07
1.22MetGln: 1.22 ± 0.071
1.877MetArg: 1.877 ± 0.084
1.988MetSer: 1.988 ± 0.081
1.791MetThr: 1.791 ± 0.08
1.861MetVal: 1.861 ± 0.092
0.152MetTrp: 0.152 ± 0.024
0.616MetTyr: 0.616 ± 0.049
0.0MetXaa: 0.0 ± 0.0
Asn
3.348AsnAla: 3.348 ± 0.121
0.497AsnCys: 0.497 ± 0.048
1.824AsnAsp: 1.824 ± 0.096
1.877AsnGlu: 1.877 ± 0.094
1.429AsnPhe: 1.429 ± 0.066
2.325AsnGly: 2.325 ± 0.086
1.08AsnHis: 1.08 ± 0.063
3.081AsnIle: 3.081 ± 0.13
1.82AsnLys: 1.82 ± 0.091
3.758AsnLeu: 3.758 ± 0.108
1.019AsnMet: 1.019 ± 0.068
1.664AsnAsn: 1.664 ± 0.088
1.906AsnPro: 1.906 ± 0.098
1.512AsnGln: 1.512 ± 0.088
2.514AsnArg: 2.514 ± 0.084
2.021AsnSer: 2.021 ± 0.095
2.115AsnThr: 2.115 ± 0.087
2.592AsnVal: 2.592 ± 0.085
0.481AsnTrp: 0.481 ± 0.043
1.154AsnTyr: 1.154 ± 0.068
0.0AsnXaa: 0.0 ± 0.0
Pro
3.233ProAla: 3.233 ± 0.105
0.464ProCys: 0.464 ± 0.042
2.255ProAsp: 2.255 ± 0.085
2.777ProGlu: 2.777 ± 0.107
1.717ProPhe: 1.717 ± 0.086
2.953ProGly: 2.953 ± 0.116
1.076ProHis: 1.076 ± 0.067
2.571ProIle: 2.571 ± 0.111
1.852ProLys: 1.852 ± 0.083
4.703ProLeu: 4.703 ± 0.15
1.15ProMet: 1.15 ± 0.067
1.355ProAsn: 1.355 ± 0.077
1.569ProPro: 1.569 ± 0.085
1.458ProGln: 1.458 ± 0.073
2.004ProArg: 2.004 ± 0.09
2.69ProSer: 2.69 ± 0.101
2.029ProThr: 2.029 ± 0.089
3.245ProVal: 3.245 ± 0.102
0.546ProTrp: 0.546 ± 0.057
1.372ProTyr: 1.372 ± 0.073
0.0ProXaa: 0.0 ± 0.0
Gln
3.804GlnAla: 3.804 ± 0.134
0.542GlnCys: 0.542 ± 0.053
1.676GlnAsp: 1.676 ± 0.08
2.033GlnGlu: 2.033 ± 0.109
1.302GlnPhe: 1.302 ± 0.074
2.69GlnGly: 2.69 ± 0.115
1.327GlnHis: 1.327 ± 0.076
2.251GlnIle: 2.251 ± 0.101
2.177GlnLys: 2.177 ± 0.092
4.654GlnLeu: 4.654 ± 0.147
1.088GlnMet: 1.088 ± 0.072
1.282GlnAsn: 1.282 ± 0.078
1.75GlnPro: 1.75 ± 0.081
2.115GlnGln: 2.115 ± 0.101
2.896GlnArg: 2.896 ± 0.112
2.033GlnSer: 2.033 ± 0.105
1.803GlnThr: 1.803 ± 0.094
3.048GlnVal: 3.048 ± 0.112
0.538GlnTrp: 0.538 ± 0.049
1.175GlnTyr: 1.175 ± 0.076
0.0GlnXaa: 0.0 ± 0.0
Arg
5.34ArgAla: 5.34 ± 0.152
0.85ArgCys: 0.85 ± 0.064
3.019ArgAsp: 3.019 ± 0.159
3.721ArgGlu: 3.721 ± 0.132
2.904ArgPhe: 2.904 ± 0.124
4.128ArgGly: 4.128 ± 0.131
1.877ArgHis: 1.877 ± 0.085
4.403ArgIle: 4.403 ± 0.126
2.978ArgLys: 2.978 ± 0.119
7.27ArgLeu: 7.27 ± 0.203
1.733ArgMet: 1.733 ± 0.084
2.403ArgAsn: 2.403 ± 0.099
2.292ArgPro: 2.292 ± 0.104
3.261ArgGln: 3.261 ± 0.109
4.49ArgArg: 4.49 ± 0.182
3.38ArgSer: 3.38 ± 0.127
2.752ArgThr: 2.752 ± 0.112
4.231ArgVal: 4.231 ± 0.142
0.801ArgTrp: 0.801 ± 0.066
2.317ArgTyr: 2.317 ± 0.113
0.0ArgXaa: 0.0 ± 0.0
Ser
5.471SerAla: 5.471 ± 0.17
0.854SerCys: 0.854 ± 0.058
3.179SerAsp: 3.179 ± 0.117
3.36SerGlu: 3.36 ± 0.111
2.337SerPhe: 2.337 ± 0.106
5.221SerGly: 5.221 ± 0.155
1.618SerHis: 1.618 ± 0.085
3.98SerIle: 3.98 ± 0.13
2.563SerLys: 2.563 ± 0.1
6.946SerLeu: 6.946 ± 0.19
1.848SerMet: 1.848 ± 0.089
2.099SerAsn: 2.099 ± 0.082
2.493SerPro: 2.493 ± 0.098
2.362SerGln: 2.362 ± 0.105
4.038SerArg: 4.038 ± 0.129
4.223SerSer: 4.223 ± 0.135
3.212SerThr: 3.212 ± 0.117
3.931SerVal: 3.931 ± 0.117
0.789SerTrp: 0.789 ± 0.059
1.885SerTyr: 1.885 ± 0.091
0.0SerXaa: 0.0 ± 0.0
Thr
4.37ThrAla: 4.37 ± 0.139
0.731ThrCys: 0.731 ± 0.057
2.588ThrAsp: 2.588 ± 0.101
2.608ThrGlu: 2.608 ± 0.111
2.062ThrPhe: 2.062 ± 0.09
3.964ThrGly: 3.964 ± 0.138
1.405ThrHis: 1.405 ± 0.077
3.335ThrIle: 3.335 ± 0.11
1.84ThrLys: 1.84 ± 0.089
7.168ThrLeu: 7.168 ± 0.201
1.162ThrMet: 1.162 ± 0.063
1.614ThrAsn: 1.614 ± 0.09
2.67ThrPro: 2.67 ± 0.091
1.935ThrGln: 1.935 ± 0.096
3.052ThrArg: 3.052 ± 0.12
2.974ThrSer: 2.974 ± 0.11
2.785ThrThr: 2.785 ± 0.121
3.656ThrVal: 3.656 ± 0.111
0.608ThrTrp: 0.608 ± 0.049
1.306ThrTyr: 1.306 ± 0.063
0.0ThrXaa: 0.0 ± 0.0
Val
5.804ValAla: 5.804 ± 0.172
0.85ValCys: 0.85 ± 0.058
3.635ValAsp: 3.635 ± 0.142
3.828ValGlu: 3.828 ± 0.152
2.477ValPhe: 2.477 ± 0.101
4.555ValGly: 4.555 ± 0.146
1.561ValHis: 1.561 ± 0.075
5.118ValIle: 5.118 ± 0.148
3.434ValLys: 3.434 ± 0.136
7.233ValLeu: 7.233 ± 0.146
2.029ValMet: 2.029 ± 0.091
2.855ValAsn: 2.855 ± 0.108
2.883ValPro: 2.883 ± 0.103
2.206ValGln: 2.206 ± 0.085
4.309ValArg: 4.309 ± 0.126
4.453ValSer: 4.453 ± 0.14
3.902ValThr: 3.902 ± 0.149
5.381ValVal: 5.381 ± 0.192
0.711ValTrp: 0.711 ± 0.053
1.75ValTyr: 1.75 ± 0.081
0.0ValXaa: 0.0 ± 0.0
Trp
0.735TrpAla: 0.735 ± 0.051
0.173TrpCys: 0.173 ± 0.024
0.476TrpAsp: 0.476 ± 0.048
0.481TrpGlu: 0.481 ± 0.042
0.481TrpPhe: 0.481 ± 0.041
0.649TrpGly: 0.649 ± 0.049
0.407TrpHis: 0.407 ± 0.043
0.748TrpIle: 0.748 ± 0.065
0.534TrpLys: 0.534 ± 0.049
1.61TrpLeu: 1.61 ± 0.092
0.378TrpMet: 0.378 ± 0.042
0.329TrpAsn: 0.329 ± 0.038
0.53TrpPro: 0.53 ± 0.048
0.78TrpGln: 0.78 ± 0.069
0.858TrpArg: 0.858 ± 0.069
0.612TrpSer: 0.612 ± 0.051
0.431TrpThr: 0.431 ± 0.043
0.83TrpVal: 0.83 ± 0.063
0.119TrpTrp: 0.119 ± 0.024
0.403TrpTyr: 0.403 ± 0.046
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.497TyrAla: 2.497 ± 0.105
0.645TyrCys: 0.645 ± 0.059
1.47TyrAsp: 1.47 ± 0.074
1.343TyrGlu: 1.343 ± 0.067
1.249TyrPhe: 1.249 ± 0.066
2.046TyrGly: 2.046 ± 0.087
1.043TyrHis: 1.043 ± 0.072
1.737TyrIle: 1.737 ± 0.09
1.088TyrLys: 1.088 ± 0.076
3.516TyrLeu: 3.516 ± 0.134
0.657TyrMet: 0.657 ± 0.051
1.167TyrAsn: 1.167 ± 0.065
1.195TyrPro: 1.195 ± 0.07
1.618TyrGln: 1.618 ± 0.077
2.099TyrArg: 2.099 ± 0.097
1.799TyrSer: 1.799 ± 0.086
1.458TyrThr: 1.458 ± 0.086
1.865TyrVal: 1.865 ± 0.091
0.407TyrTrp: 0.407 ± 0.04
1.125TyrTyr: 1.125 ± 0.073
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 918 proteins (243457 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski