Amino acid dipepetide frequency for Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern corn leaf blight fungus) (Bipolaris maydis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.096AlaAla: 9.096 ± 0.071
1.178AlaCys: 1.178 ± 0.015
4.214AlaAsp: 4.214 ± 0.03
5.083AlaGlu: 5.083 ± 0.04
3.204AlaPhe: 3.204 ± 0.028
5.649AlaGly: 5.649 ± 0.036
1.95AlaHis: 1.95 ± 0.021
4.361AlaIle: 4.361 ± 0.035
4.449AlaLys: 4.449 ± 0.037
7.737AlaLeu: 7.737 ± 0.048
2.054AlaMet: 2.054 ± 0.02
3.193AlaAsn: 3.193 ± 0.025
5.14AlaPro: 5.14 ± 0.048
3.67AlaGln: 3.67 ± 0.033
4.972AlaArg: 4.972 ± 0.034
7.465AlaSer: 7.465 ± 0.044
5.437AlaThr: 5.437 ± 0.034
5.257AlaVal: 5.257 ± 0.036
1.2AlaTrp: 1.2 ± 0.016
2.32AlaTyr: 2.32 ± 0.021
0.0AlaXaa: 0.0 ± 0.0
Cys
1.035CysAla: 1.035 ± 0.015
0.277CysCys: 0.277 ± 0.009
0.688CysAsp: 0.688 ± 0.012
0.627CysGlu: 0.627 ± 0.011
0.565CysPhe: 0.565 ± 0.01
0.994CysGly: 0.994 ± 0.016
0.345CysHis: 0.345 ± 0.008
0.776CysIle: 0.776 ± 0.011
0.583CysLys: 0.583 ± 0.011
1.237CysLeu: 1.237 ± 0.016
0.316CysMet: 0.316 ± 0.009
0.497CysAsn: 0.497 ± 0.011
0.696CysPro: 0.696 ± 0.015
0.475CysGln: 0.475 ± 0.01
0.768CysArg: 0.768 ± 0.013
0.978CysSer: 0.978 ± 0.016
0.799CysThr: 0.799 ± 0.013
0.847CysVal: 0.847 ± 0.013
0.215CysTrp: 0.215 ± 0.007
0.379CysTyr: 0.379 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.979AspAla: 4.979 ± 0.033
0.646AspCys: 0.646 ± 0.012
4.139AspAsp: 4.139 ± 0.043
4.344AspGlu: 4.344 ± 0.037
2.197AspPhe: 2.197 ± 0.023
3.788AspGly: 3.788 ± 0.027
1.183AspHis: 1.183 ± 0.014
3.007AspIle: 3.007 ± 0.028
2.524AspLys: 2.524 ± 0.028
4.719AspLeu: 4.719 ± 0.036
1.395AspMet: 1.395 ± 0.013
1.873AspAsn: 1.873 ± 0.02
3.176AspPro: 3.176 ± 0.025
1.829AspGln: 1.829 ± 0.019
2.896AspArg: 2.896 ± 0.024
3.903AspSer: 3.903 ± 0.036
3.029AspThr: 3.029 ± 0.024
3.69AspVal: 3.69 ± 0.028
0.901AspTrp: 0.901 ± 0.013
1.615AspTyr: 1.615 ± 0.017
0.0AspXaa: 0.0 ± 0.0
Glu
5.397GluAla: 5.397 ± 0.045
0.659GluCys: 0.659 ± 0.011
4.068GluAsp: 4.068 ± 0.036
5.393GluGlu: 5.393 ± 0.056
1.903GluPhe: 1.903 ± 0.015
3.705GluGly: 3.705 ± 0.03
1.494GluHis: 1.494 ± 0.018
2.942GluIle: 2.942 ± 0.025
3.872GluLys: 3.872 ± 0.033
4.941GluLeu: 4.941 ± 0.032
1.469GluMet: 1.469 ± 0.016
2.231GluAsn: 2.231 ± 0.02
2.708GluPro: 2.708 ± 0.038
2.625GluGln: 2.625 ± 0.028
3.908GluArg: 3.908 ± 0.038
3.966GluSer: 3.966 ± 0.032
3.301GluThr: 3.301 ± 0.027
3.412GluVal: 3.412 ± 0.028
0.939GluTrp: 0.939 ± 0.013
1.706GluTyr: 1.706 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
3.173PheAla: 3.173 ± 0.029
0.566PheCys: 0.566 ± 0.011
2.298PheAsp: 2.298 ± 0.021
2.11PheGlu: 2.11 ± 0.019
1.645PhePhe: 1.645 ± 0.02
2.823PheGly: 2.823 ± 0.029
0.859PheHis: 0.859 ± 0.012
1.773PheIle: 1.773 ± 0.018
1.601PheLys: 1.601 ± 0.019
3.355PheLeu: 3.355 ± 0.028
0.781PheMet: 0.781 ± 0.013
1.465PheAsn: 1.465 ± 0.017
1.907PhePro: 1.907 ± 0.02
1.371PheGln: 1.371 ± 0.016
1.886PheArg: 1.886 ± 0.02
2.983PheSer: 2.983 ± 0.025
2.227PheThr: 2.227 ± 0.023
2.391PheVal: 2.391 ± 0.023
0.648PheTrp: 0.648 ± 0.012
1.087PheTyr: 1.087 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.348GlyAla: 5.348 ± 0.046
0.943GlyCys: 0.943 ± 0.015
3.426GlyAsp: 3.426 ± 0.031
3.586GlyGlu: 3.586 ± 0.026
2.77GlyPhe: 2.77 ± 0.028
5.697GlyGly: 5.697 ± 0.061
1.692GlyHis: 1.692 ± 0.02
3.479GlyIle: 3.479 ± 0.028
3.617GlyLys: 3.617 ± 0.032
5.799GlyLeu: 5.799 ± 0.036
1.656GlyMet: 1.656 ± 0.019
2.548GlyAsn: 2.548 ± 0.024
3.207GlyPro: 3.207 ± 0.029
2.546GlyGln: 2.546 ± 0.025
3.94GlyArg: 3.94 ± 0.028
5.326GlySer: 5.326 ± 0.036
3.936GlyThr: 3.936 ± 0.031
4.284GlyVal: 4.284 ± 0.032
1.176GlyTrp: 1.176 ± 0.017
2.153GlyTyr: 2.153 ± 0.023
0.0GlyXaa: 0.0 ± 0.0
His
2.064HisAla: 2.064 ± 0.02
0.383HisCys: 0.383 ± 0.008
1.359HisAsp: 1.359 ± 0.018
1.382HisGlu: 1.382 ± 0.017
0.922HisPhe: 0.922 ± 0.014
1.738HisGly: 1.738 ± 0.02
0.889HisHis: 0.889 ± 0.018
1.266HisIle: 1.266 ± 0.014
0.998HisLys: 0.998 ± 0.015
2.256HisLeu: 2.256 ± 0.023
0.556HisMet: 0.556 ± 0.012
0.907HisAsn: 0.907 ± 0.013
1.66HisPro: 1.66 ± 0.019
1.027HisGln: 1.027 ± 0.015
1.476HisArg: 1.476 ± 0.017
1.893HisSer: 1.893 ± 0.021
1.426HisThr: 1.426 ± 0.017
1.545HisVal: 1.545 ± 0.018
0.35HisTrp: 0.35 ± 0.008
0.729HisTyr: 0.729 ± 0.011
0.0HisXaa: 0.0 ± 0.0
Ile
4.398IleAla: 4.398 ± 0.037
0.758IleCys: 0.758 ± 0.012
2.837IleAsp: 2.837 ± 0.021
2.873IleGlu: 2.873 ± 0.025
1.944IlePhe: 1.944 ± 0.021
3.203IleGly: 3.203 ± 0.031
1.231IleHis: 1.231 ± 0.016
2.491IleIle: 2.491 ± 0.027
2.345IleLys: 2.345 ± 0.023
4.392IleLeu: 4.392 ± 0.033
1.044IleMet: 1.044 ± 0.015
1.843IleAsn: 1.843 ± 0.016
3.032IlePro: 3.032 ± 0.025
1.933IleGln: 1.933 ± 0.018
2.75IleArg: 2.75 ± 0.021
3.755IleSer: 3.755 ± 0.029
2.948IleThr: 2.948 ± 0.025
3.184IleVal: 3.184 ± 0.028
0.748IleTrp: 0.748 ± 0.013
1.432IleTyr: 1.432 ± 0.018
0.0IleXaa: 0.0 ± 0.0
Lys
4.458LysAla: 4.458 ± 0.038
0.545LysCys: 0.545 ± 0.011
2.985LysAsp: 2.985 ± 0.027
3.648LysGlu: 3.648 ± 0.037
1.491LysPhe: 1.491 ± 0.018
3.157LysGly: 3.157 ± 0.027
1.236LysHis: 1.236 ± 0.016
2.372LysIle: 2.372 ± 0.027
3.719LysLys: 3.719 ± 0.046
4.155LysLeu: 4.155 ± 0.036
1.096LysMet: 1.096 ± 0.016
1.938LysAsn: 1.938 ± 0.02
2.906LysPro: 2.906 ± 0.025
2.065LysGln: 2.065 ± 0.017
3.546LysArg: 3.546 ± 0.033
3.638LysSer: 3.638 ± 0.029
2.991LysThr: 2.991 ± 0.023
2.865LysVal: 2.865 ± 0.024
0.725LysTrp: 0.725 ± 0.012
1.459LysTyr: 1.459 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
7.768LeuAla: 7.768 ± 0.045
1.257LeuCys: 1.257 ± 0.017
5.003LeuAsp: 5.003 ± 0.038
5.299LeuGlu: 5.299 ± 0.04
3.237LeuPhe: 3.237 ± 0.028
5.653LeuGly: 5.653 ± 0.037
2.301LeuHis: 2.301 ± 0.021
3.881LeuIle: 3.881 ± 0.033
4.25LeuLys: 4.25 ± 0.032
8.091LeuLeu: 8.091 ± 0.059
1.757LeuMet: 1.757 ± 0.021
3.125LeuAsn: 3.125 ± 0.023
5.481LeuPro: 5.481 ± 0.035
3.814LeuGln: 3.814 ± 0.035
5.494LeuArg: 5.494 ± 0.036
6.971LeuSer: 6.971 ± 0.039
4.693LeuThr: 4.693 ± 0.032
5.342LeuVal: 5.342 ± 0.035
1.173LeuTrp: 1.173 ± 0.016
2.38LeuTyr: 2.38 ± 0.021
0.0LeuXaa: 0.0 ± 0.0
Met
2.259MetAla: 2.259 ± 0.022
0.28MetCys: 0.28 ± 0.007
1.294MetAsp: 1.294 ± 0.018
1.275MetGlu: 1.275 ± 0.017
0.779MetPhe: 0.779 ± 0.012
1.518MetGly: 1.518 ± 0.019
0.566MetHis: 0.566 ± 0.011
0.974MetIle: 0.974 ± 0.014
1.062MetLys: 1.062 ± 0.015
1.954MetLeu: 1.954 ± 0.022
0.596MetMet: 0.596 ± 0.011
0.839MetAsn: 0.839 ± 0.013
1.373MetPro: 1.373 ± 0.015
0.98MetGln: 0.98 ± 0.017
1.346MetArg: 1.346 ± 0.014
1.941MetSer: 1.941 ± 0.02
1.316MetThr: 1.316 ± 0.015
1.331MetVal: 1.331 ± 0.016
0.275MetTrp: 0.275 ± 0.006
0.614MetTyr: 0.614 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.382AsnAla: 3.382 ± 0.029
0.465AsnCys: 0.465 ± 0.01
1.999AsnAsp: 1.999 ± 0.021
2.047AsnGlu: 2.047 ± 0.02
1.401AsnPhe: 1.401 ± 0.017
3.035AsnGly: 3.035 ± 0.031
0.873AsnHis: 0.873 ± 0.011
2.055AsnIle: 2.055 ± 0.02
1.775AsnLys: 1.775 ± 0.02
3.256AsnLeu: 3.256 ± 0.025
0.929AsnMet: 0.929 ± 0.014
1.617AsnAsn: 1.617 ± 0.023
2.438AsnPro: 2.438 ± 0.021
1.424AsnGln: 1.424 ± 0.017
1.891AsnArg: 1.891 ± 0.02
2.768AsnSer: 2.768 ± 0.022
2.342AsnThr: 2.342 ± 0.021
2.41AsnVal: 2.41 ± 0.023
0.579AsnTrp: 0.579 ± 0.012
1.099AsnTyr: 1.099 ± 0.015
0.0AsnXaa: 0.0 ± 0.0
Pro
5.332ProAla: 5.332 ± 0.047
0.581ProCys: 0.581 ± 0.013
3.077ProAsp: 3.077 ± 0.027
3.647ProGlu: 3.647 ± 0.034
2.048ProPhe: 2.048 ± 0.02
3.724ProGly: 3.724 ± 0.035
1.445ProHis: 1.445 ± 0.016
2.612ProIle: 2.612 ± 0.019
2.87ProLys: 2.87 ± 0.026
4.681ProLeu: 4.681 ± 0.032
1.152ProMet: 1.152 ± 0.015
2.339ProAsn: 2.339 ± 0.021
5.169ProPro: 5.169 ± 0.067
2.669ProGln: 2.669 ± 0.03
3.341ProArg: 3.341 ± 0.029
5.899ProSer: 5.899 ± 0.051
4.227ProThr: 4.227 ± 0.039
3.517ProVal: 3.517 ± 0.028
0.751ProTrp: 0.751 ± 0.013
1.608ProTyr: 1.608 ± 0.018
0.0ProXaa: 0.0 ± 0.0
Gln
3.586GlnAla: 3.586 ± 0.033
0.509GlnCys: 0.509 ± 0.01
2.19GlnAsp: 2.19 ± 0.021
2.431GlnGlu: 2.431 ± 0.023
1.28GlnPhe: 1.28 ± 0.015
2.488GlnGly: 2.488 ± 0.026
1.211GlnHis: 1.211 ± 0.017
1.919GlnIle: 1.919 ± 0.019
2.109GlnLys: 2.109 ± 0.022
3.446GlnLeu: 3.446 ± 0.03
0.914GlnMet: 0.914 ± 0.017
1.648GlnAsn: 1.648 ± 0.018
2.651GlnPro: 2.651 ± 0.028
2.789GlnGln: 2.789 ± 0.05
2.748GlnArg: 2.748 ± 0.023
3.197GlnSer: 3.197 ± 0.026
2.37GlnThr: 2.37 ± 0.023
2.172GlnVal: 2.172 ± 0.021
0.606GlnTrp: 0.606 ± 0.01
1.239GlnTyr: 1.239 ± 0.017
0.0GlnXaa: 0.0 ± 0.0
Arg
4.682ArgAla: 4.682 ± 0.031
0.769ArgCys: 0.769 ± 0.013
3.225ArgAsp: 3.225 ± 0.03
3.673ArgGlu: 3.673 ± 0.035
2.118ArgPhe: 2.118 ± 0.021
3.565ArgGly: 3.565 ± 0.032
1.56ArgHis: 1.56 ± 0.018
2.981ArgIle: 2.981 ± 0.023
3.541ArgLys: 3.541 ± 0.034
5.254ArgLeu: 5.254 ± 0.036
1.381ArgMet: 1.381 ± 0.016
2.369ArgAsn: 2.369 ± 0.023
3.456ArgPro: 3.456 ± 0.029
2.605ArgGln: 2.605 ± 0.024
4.77ArgArg: 4.77 ± 0.042
4.551ArgSer: 4.551 ± 0.036
3.301ArgThr: 3.301 ± 0.023
3.223ArgVal: 3.223 ± 0.024
0.919ArgTrp: 0.919 ± 0.012
1.681ArgTyr: 1.681 ± 0.018
0.0ArgXaa: 0.0 ± 0.0
Ser
6.679SerAla: 6.679 ± 0.038
0.933SerCys: 0.933 ± 0.015
4.041SerAsp: 4.041 ± 0.033
3.978SerGlu: 3.978 ± 0.031
2.988SerPhe: 2.988 ± 0.025
5.278SerGly: 5.278 ± 0.036
2.027SerHis: 2.027 ± 0.023
3.976SerIle: 3.976 ± 0.034
3.873SerLys: 3.873 ± 0.027
6.924SerLeu: 6.924 ± 0.041
1.788SerMet: 1.788 ± 0.019
3.09SerAsn: 3.09 ± 0.025
5.397SerPro: 5.397 ± 0.051
3.223SerGln: 3.223 ± 0.024
4.744SerArg: 4.744 ± 0.038
8.259SerSer: 8.259 ± 0.06
5.551SerThr: 5.551 ± 0.037
4.454SerVal: 4.454 ± 0.028
1.093SerTrp: 1.093 ± 0.014
2.145SerTyr: 2.145 ± 0.024
0.0SerXaa: 0.0 ± 0.0
Thr
5.299ThrAla: 5.299 ± 0.037
0.85ThrCys: 0.85 ± 0.016
2.801ThrAsp: 2.801 ± 0.021
3.013ThrGlu: 3.013 ± 0.024
2.265ThrPhe: 2.265 ± 0.021
4.053ThrGly: 4.053 ± 0.03
1.415ThrHis: 1.415 ± 0.017
3.134ThrIle: 3.134 ± 0.028
2.811ThrLys: 2.811 ± 0.022
5.326ThrLeu: 5.326 ± 0.037
1.257ThrMet: 1.257 ± 0.016
2.219ThrAsn: 2.219 ± 0.023
4.551ThrPro: 4.551 ± 0.044
2.229ThrGln: 2.229 ± 0.024
3.188ThrArg: 3.188 ± 0.026
5.339ThrSer: 5.339 ± 0.037
4.399ThrThr: 4.399 ± 0.04
3.687ThrVal: 3.687 ± 0.03
0.898ThrTrp: 0.898 ± 0.014
1.675ThrTyr: 1.675 ± 0.017
0.0ThrXaa: 0.0 ± 0.0
Val
5.257ValAla: 5.257 ± 0.035
0.845ValCys: 0.845 ± 0.013
3.57ValAsp: 3.57 ± 0.028
3.831ValGlu: 3.831 ± 0.027
2.436ValPhe: 2.436 ± 0.025
4.017ValGly: 4.017 ± 0.034
1.418ValHis: 1.418 ± 0.016
2.888ValIle: 2.888 ± 0.026
2.968ValLys: 2.968 ± 0.028
5.48ValLeu: 5.48 ± 0.038
1.34ValMet: 1.34 ± 0.016
2.202ValAsn: 2.202 ± 0.02
3.548ValPro: 3.548 ± 0.031
2.473ValGln: 2.473 ± 0.021
3.384ValArg: 3.384 ± 0.023
4.44ValSer: 4.44 ± 0.029
3.45ValThr: 3.45 ± 0.026
4.246ValVal: 4.246 ± 0.035
0.888ValTrp: 0.888 ± 0.014
1.746ValTyr: 1.746 ± 0.021
0.0ValXaa: 0.0 ± 0.0
Trp
1.16TrpAla: 1.16 ± 0.014
0.211TrpCys: 0.211 ± 0.006
0.916TrpAsp: 0.916 ± 0.015
0.841TrpGlu: 0.841 ± 0.013
0.543TrpPhe: 0.543 ± 0.01
0.958TrpGly: 0.958 ± 0.014
0.375TrpHis: 0.375 ± 0.009
0.801TrpIle: 0.801 ± 0.014
0.829TrpLys: 0.829 ± 0.013
1.349TrpLeu: 1.349 ± 0.015
0.384TrpMet: 0.384 ± 0.007
0.651TrpAsn: 0.651 ± 0.012
0.619TrpPro: 0.619 ± 0.011
0.6TrpGln: 0.6 ± 0.009
0.948TrpArg: 0.948 ± 0.014
1.071TrpSer: 1.071 ± 0.014
0.929TrpThr: 0.929 ± 0.013
0.903TrpVal: 0.903 ± 0.013
0.289TrpTrp: 0.289 ± 0.008
0.462TrpTyr: 0.462 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.276TyrAla: 2.276 ± 0.02
0.44TyrCys: 0.44 ± 0.01
1.704TyrAsp: 1.704 ± 0.018
1.561TyrGlu: 1.561 ± 0.017
1.215TyrPhe: 1.215 ± 0.017
2.085TyrGly: 2.085 ± 0.024
0.759TyrHis: 0.759 ± 0.012
1.456TyrIle: 1.456 ± 0.016
1.2TyrLys: 1.2 ± 0.014
2.615TyrLeu: 2.615 ± 0.025
0.708TyrMet: 0.708 ± 0.012
1.189TyrAsn: 1.189 ± 0.016
1.571TyrPro: 1.571 ± 0.021
1.154TyrGln: 1.154 ± 0.016
1.626TyrArg: 1.626 ± 0.016
2.097TyrSer: 2.097 ± 0.02
1.735TyrThr: 1.735 ± 0.019
1.669TyrVal: 1.669 ± 0.018
0.467TyrTrp: 0.467 ± 0.01
0.976TyrTyr: 0.976 ± 0.016
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12857 proteins (5528821 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski