Amino acid dipepetide frequency for Wuhan insect virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.313AlaAla: 1.313 ± 0.303
0.656AlaCys: 0.656 ± 1.153
2.954AlaAsp: 2.954 ± 0.727
1.313AlaGlu: 1.313 ± 0.581
1.313AlaPhe: 1.313 ± 1.517
1.969AlaGly: 1.969 ± 0.377
1.313AlaHis: 1.313 ± 0.303
4.595AlaIle: 4.595 ± 0.624
0.985AlaLys: 0.985 ± 0.436
3.938AlaLeu: 3.938 ± 1.083
2.297AlaMet: 2.297 ± 1.016
1.641AlaAsn: 1.641 ± 0.726
1.641AlaPro: 1.641 ± 0.812
0.656AlaGln: 0.656 ± 0.29
0.328AlaArg: 0.328 ± 0.145
5.251AlaSer: 5.251 ± 1.71
3.938AlaThr: 3.938 ± 1.055
3.282AlaVal: 3.282 ± 0.832
0.328AlaTrp: 0.328 ± 0.145
2.297AlaTyr: 2.297 ± 0.48
0.0AlaXaa: 0.0 ± 0.0
Cys
0.656CysAla: 0.656 ± 0.29
0.328CysCys: 0.328 ± 0.145
0.985CysAsp: 0.985 ± 0.436
0.328CysGlu: 0.328 ± 0.145
0.656CysPhe: 0.656 ± 0.29
1.641CysGly: 1.641 ± 0.31
0.0CysHis: 0.0 ± 0.0
0.985CysIle: 0.985 ± 1.032
1.313CysLys: 1.313 ± 0.581
0.985CysLeu: 0.985 ± 0.36
0.985CysMet: 0.985 ± 0.36
1.969CysAsn: 1.969 ± 0.377
0.985CysPro: 0.985 ± 0.436
0.0CysGln: 0.0 ± 0.0
0.328CysArg: 0.328 ± 0.145
0.985CysSer: 0.985 ± 0.36
0.985CysThr: 0.985 ± 1.032
2.297CysVal: 2.297 ± 0.65
0.656CysTrp: 0.656 ± 0.29
0.328CysTyr: 0.328 ± 0.577
0.0CysXaa: 0.0 ± 0.0
Asp
2.954AspAla: 2.954 ± 0.595
1.969AspCys: 1.969 ± 0.871
3.938AspAsp: 3.938 ± 0.359
3.61AspGlu: 3.61 ± 0.279
4.923AspPhe: 4.923 ± 1.078
2.297AspGly: 2.297 ± 0.574
0.656AspHis: 0.656 ± 0.458
4.266AspIle: 4.266 ± 0.851
5.907AspLys: 5.907 ± 1.181
4.266AspLeu: 4.266 ± 1.887
3.282AspMet: 3.282 ± 1.452
4.266AspAsn: 4.266 ± 0.892
2.297AspPro: 2.297 ± 0.574
1.313AspGln: 1.313 ± 0.581
1.969AspArg: 1.969 ± 0.377
7.22AspSer: 7.22 ± 0.558
4.923AspThr: 4.923 ± 0.929
8.533AspVal: 8.533 ± 3.15
0.985AspTrp: 0.985 ± 0.661
3.282AspTyr: 3.282 ± 0.865
0.0AspXaa: 0.0 ± 0.0
Glu
1.313GluAla: 1.313 ± 0.303
0.656GluCys: 0.656 ± 0.458
2.297GluAsp: 2.297 ± 0.48
3.61GluGlu: 3.61 ± 0.947
1.969GluPhe: 1.969 ± 0.377
0.985GluGly: 0.985 ± 0.661
1.313GluHis: 1.313 ± 0.303
3.938GluIle: 3.938 ± 0.373
4.266GluLys: 4.266 ± 0.851
5.251GluLeu: 5.251 ± 2.323
0.985GluMet: 0.985 ± 0.436
3.282GluAsn: 3.282 ± 0.619
0.985GluPro: 0.985 ± 0.436
0.985GluGln: 0.985 ± 0.661
1.641GluArg: 1.641 ± 0.726
1.641GluSer: 1.641 ± 0.31
2.954GluThr: 2.954 ± 0.285
0.985GluVal: 0.985 ± 0.436
0.0GluTrp: 0.0 ± 0.0
2.954GluTyr: 2.954 ± 0.731
0.0GluXaa: 0.0 ± 0.0
Phe
1.969PheAla: 1.969 ± 2.101
1.313PheCys: 1.313 ± 0.917
3.61PheAsp: 3.61 ± 1.003
2.297PheGlu: 2.297 ± 0.65
0.656PhePhe: 0.656 ± 0.29
0.985PheGly: 0.985 ± 0.661
1.641PheHis: 1.641 ± 1.372
3.938PheIle: 3.938 ± 2.454
2.954PheLys: 2.954 ± 0.731
2.954PheLeu: 2.954 ± 0.792
0.985PheMet: 0.985 ± 0.36
2.297PheAsn: 2.297 ± 1.016
0.656PhePro: 0.656 ± 0.458
1.641PheGln: 1.641 ± 0.812
2.626PheArg: 2.626 ± 0.601
4.595PheSer: 4.595 ± 1.328
4.266PheThr: 4.266 ± 0.493
5.251PheVal: 5.251 ± 0.543
0.0PheTrp: 0.0 ± 0.0
3.282PheTyr: 3.282 ± 1.541
0.0PheXaa: 0.0 ± 0.0
Gly
2.954GlyAla: 2.954 ± 0.731
0.656GlyCys: 0.656 ± 0.29
2.954GlyAsp: 2.954 ± 1.307
0.0GlyGlu: 0.0 ± 0.0
1.641GlyPhe: 1.641 ± 0.547
1.641GlyGly: 1.641 ± 0.726
0.656GlyHis: 0.656 ± 0.29
3.61GlyIle: 3.61 ± 0.674
1.969GlyLys: 1.969 ± 0.871
2.626GlyLeu: 2.626 ± 0.382
0.985GlyMet: 0.985 ± 0.36
1.313GlyAsn: 1.313 ± 0.91
0.656GlyPro: 0.656 ± 1.153
0.985GlyGln: 0.985 ± 0.436
0.985GlyArg: 0.985 ± 0.436
2.297GlySer: 2.297 ± 1.016
0.656GlyThr: 0.656 ± 0.458
1.641GlyVal: 1.641 ± 1.412
0.0GlyTrp: 0.0 ± 0.0
2.297GlyTyr: 2.297 ± 1.016
0.0GlyXaa: 0.0 ± 0.0
His
0.985HisAla: 0.985 ± 0.436
0.328HisCys: 0.328 ± 0.145
2.954HisAsp: 2.954 ± 0.731
1.313HisGlu: 1.313 ± 0.581
0.656HisPhe: 0.656 ± 0.458
1.641HisGly: 1.641 ± 0.31
0.985HisHis: 0.985 ± 0.36
1.969HisIle: 1.969 ± 2.587
2.954HisLys: 2.954 ± 0.285
2.626HisLeu: 2.626 ± 1.169
1.313HisMet: 1.313 ± 0.581
1.641HisAsn: 1.641 ± 0.31
0.328HisPro: 0.328 ± 0.145
0.0HisGln: 0.0 ± 0.0
0.985HisArg: 0.985 ± 0.36
2.954HisSer: 2.954 ± 1.128
0.985HisThr: 0.985 ± 1.032
1.313HisVal: 1.313 ± 0.581
0.0HisTrp: 0.0 ± 0.0
3.61HisTyr: 3.61 ± 0.503
0.0HisXaa: 0.0 ± 0.0
Ile
3.938IleAla: 3.938 ± 0.909
1.313IleCys: 1.313 ± 0.581
5.579IleAsp: 5.579 ± 1.116
2.954IleGlu: 2.954 ± 0.595
3.938IlePhe: 3.938 ± 1.269
1.313IleGly: 1.313 ± 0.589
1.969IleHis: 1.969 ± 1.227
6.564IleIle: 6.564 ± 3.629
8.205IleLys: 8.205 ± 1.999
7.877IleLeu: 7.877 ± 2.811
3.282IleMet: 3.282 ± 1.135
3.938IleAsn: 3.938 ± 1.269
3.61IlePro: 3.61 ± 0.279
0.985IleGln: 0.985 ± 0.436
2.954IleArg: 2.954 ± 0.731
5.907IleSer: 5.907 ± 1.996
6.564IleThr: 6.564 ± 4.762
6.236IleVal: 6.236 ± 1.44
0.328IleTrp: 0.328 ± 0.145
3.282IleTyr: 3.282 ± 1.452
0.0IleXaa: 0.0 ± 0.0
Lys
2.954LysAla: 2.954 ± 0.727
1.313LysCys: 1.313 ± 0.917
3.61LysAsp: 3.61 ± 1.003
2.626LysGlu: 2.626 ± 0.601
8.533LysPhe: 8.533 ± 0.986
1.641LysGly: 1.641 ± 0.726
2.626LysHis: 2.626 ± 0.606
7.22LysIle: 7.22 ± 1.099
9.189LysLys: 9.189 ± 1.694
7.22LysLeu: 7.22 ± 3.194
0.985LysMet: 0.985 ± 1.05
4.923LysAsn: 4.923 ± 0.787
2.297LysPro: 2.297 ± 0.574
0.985LysGln: 0.985 ± 0.36
2.626LysArg: 2.626 ± 2.071
6.236LysSer: 6.236 ± 2.14
7.877LysThr: 7.877 ± 1.053
2.626LysVal: 2.626 ± 1.161
0.328LysTrp: 0.328 ± 0.577
8.205LysTyr: 8.205 ± 3.375
0.0LysXaa: 0.0 ± 0.0
Leu
4.266LeuAla: 4.266 ± 0.493
0.985LeuCys: 0.985 ± 0.436
4.266LeuAsp: 4.266 ± 0.851
2.626LeuGlu: 2.626 ± 0.601
2.954LeuPhe: 2.954 ± 0.285
1.641LeuGly: 1.641 ± 0.31
2.297LeuHis: 2.297 ± 1.016
5.251LeuIle: 5.251 ± 0.979
6.892LeuLys: 6.892 ± 0.471
4.595LeuLeu: 4.595 ± 2.644
2.297LeuMet: 2.297 ± 2.099
4.266LeuAsn: 4.266 ± 0.851
3.282LeuPro: 3.282 ± 0.242
3.61LeuGln: 3.61 ± 0.947
0.328LeuArg: 0.328 ± 0.577
6.892LeuSer: 6.892 ± 1.099
5.907LeuThr: 5.907 ± 1.131
3.938LeuVal: 3.938 ± 0.359
0.656LeuTrp: 0.656 ± 0.29
6.892LeuTyr: 6.892 ± 0.471
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.313MetCys: 1.313 ± 0.917
1.641MetAsp: 1.641 ± 0.726
0.656MetGlu: 0.656 ± 0.458
1.969MetPhe: 1.969 ± 0.721
0.0MetGly: 0.0 ± 0.0
1.313MetHis: 1.313 ± 0.303
4.923MetIle: 4.923 ± 0.76
3.282MetLys: 3.282 ± 1.903
2.626MetLeu: 2.626 ± 0.639
1.313MetMet: 1.313 ± 0.303
0.656MetAsn: 0.656 ± 0.29
1.641MetPro: 1.641 ± 1.736
1.313MetGln: 1.313 ± 0.303
1.969MetArg: 1.969 ± 0.871
4.595MetSer: 4.595 ± 0.818
3.61MetThr: 3.61 ± 0.948
0.328MetVal: 0.328 ± 0.145
0.985MetTrp: 0.985 ± 0.36
2.954MetTyr: 2.954 ± 1.68
0.0MetXaa: 0.0 ± 0.0
Asn
1.969AsnAla: 1.969 ± 0.542
0.656AsnCys: 0.656 ± 0.29
6.236AsnAsp: 6.236 ± 0.353
0.656AsnGlu: 0.656 ± 0.29
1.969AsnPhe: 1.969 ± 1.375
1.313AsnGly: 1.313 ± 0.581
0.985AsnHis: 0.985 ± 0.436
4.923AsnIle: 4.923 ± 0.66
4.923AsnLys: 4.923 ± 1.389
3.938AsnLeu: 3.938 ± 1.142
1.969AsnMet: 1.969 ± 0.377
2.954AsnAsn: 2.954 ± 0.731
0.328AsnPro: 0.328 ± 0.577
1.313AsnGln: 1.313 ± 0.581
2.954AsnArg: 2.954 ± 1.245
3.938AsnSer: 3.938 ± 1.07
2.954AsnThr: 2.954 ± 0.731
5.907AsnVal: 5.907 ± 1.996
0.328AsnTrp: 0.328 ± 0.145
3.61AsnTyr: 3.61 ± 2.862
0.0AsnXaa: 0.0 ± 0.0
Pro
1.641ProAla: 1.641 ± 0.726
0.328ProCys: 0.328 ± 0.145
1.641ProAsp: 1.641 ± 0.726
1.969ProGlu: 1.969 ± 0.871
0.328ProPhe: 0.328 ± 0.577
1.969ProGly: 1.969 ± 0.721
0.656ProHis: 0.656 ± 0.29
2.626ProIle: 2.626 ± 0.639
1.969ProLys: 1.969 ± 1.607
0.985ProLeu: 0.985 ± 0.36
1.641ProMet: 1.641 ± 1.372
1.641ProAsn: 1.641 ± 0.31
1.313ProPro: 1.313 ± 0.303
0.985ProGln: 0.985 ± 0.36
1.313ProArg: 1.313 ± 0.589
2.954ProSer: 2.954 ± 1.245
2.626ProThr: 2.626 ± 1.161
2.297ProVal: 2.297 ± 0.65
0.0ProTrp: 0.0 ± 0.0
1.641ProTyr: 1.641 ± 1.372
0.0ProXaa: 0.0 ± 0.0
Gln
0.985GlnAla: 0.985 ± 0.436
0.328GlnCys: 0.328 ± 0.577
1.313GlnAsp: 1.313 ± 0.581
2.954GlnGlu: 2.954 ± 0.731
0.985GlnPhe: 0.985 ± 1.032
0.656GlnGly: 0.656 ± 0.29
0.328GlnHis: 0.328 ± 0.577
2.297GlnIle: 2.297 ± 0.574
0.985GlnLys: 0.985 ± 0.661
1.641GlnLeu: 1.641 ± 0.726
0.328GlnMet: 0.328 ± 0.145
1.313GlnAsn: 1.313 ± 0.581
0.985GlnPro: 0.985 ± 0.36
0.985GlnGln: 0.985 ± 0.661
1.313GlnArg: 1.313 ± 0.581
0.985GlnSer: 0.985 ± 0.36
1.969GlnThr: 1.969 ± 0.871
1.969GlnVal: 1.969 ± 0.542
0.0GlnTrp: 0.0 ± 0.0
0.985GlnTyr: 0.985 ± 1.032
0.0GlnXaa: 0.0 ± 0.0
Arg
1.969ArgAla: 1.969 ± 0.871
1.313ArgCys: 1.313 ± 0.581
0.328ArgAsp: 0.328 ± 0.145
0.985ArgGlu: 0.985 ± 0.661
1.313ArgPhe: 1.313 ± 0.303
0.328ArgGly: 0.328 ± 0.145
0.985ArgHis: 0.985 ± 0.436
2.626ArgIle: 2.626 ± 0.382
2.626ArgLys: 2.626 ± 1.161
2.954ArgLeu: 2.954 ± 1.307
1.313ArgMet: 1.313 ± 0.581
3.61ArgAsn: 3.61 ± 0.503
1.313ArgPro: 1.313 ± 0.303
0.328ArgGln: 0.328 ± 0.145
1.313ArgArg: 1.313 ± 1.509
4.923ArgSer: 4.923 ± 4.472
3.282ArgThr: 3.282 ± 2.823
1.969ArgVal: 1.969 ± 0.542
0.0ArgTrp: 0.0 ± 0.0
3.282ArgTyr: 3.282 ± 0.242
0.0ArgXaa: 0.0 ± 0.0
Ser
3.938SerAla: 3.938 ± 1.083
0.985SerCys: 0.985 ± 0.436
7.548SerAsp: 7.548 ± 2.145
3.938SerGlu: 3.938 ± 1.742
2.626SerPhe: 2.626 ± 1.161
2.626SerGly: 2.626 ± 1.161
2.297SerHis: 2.297 ± 1.016
7.22SerIle: 7.22 ± 0.406
7.548SerLys: 7.548 ± 1.244
5.907SerLeu: 5.907 ± 1.405
2.297SerMet: 2.297 ± 1.082
4.595SerAsn: 4.595 ± 0.899
0.985SerPro: 0.985 ± 0.436
1.641SerGln: 1.641 ± 0.726
4.923SerArg: 4.923 ± 4.235
3.61SerSer: 3.61 ± 0.503
5.251SerThr: 5.251 ± 1.598
5.251SerVal: 5.251 ± 0.782
0.328SerTrp: 0.328 ± 0.863
5.579SerTyr: 5.579 ± 1.048
0.0SerXaa: 0.0 ± 0.0
Thr
0.985ThrAla: 0.985 ± 0.436
0.656ThrCys: 0.656 ± 0.458
6.892ThrAsp: 6.892 ± 1.61
3.282ThrGlu: 3.282 ± 0.647
3.61ThrPhe: 3.61 ± 1.893
2.954ThrGly: 2.954 ± 0.731
1.969ThrHis: 1.969 ± 0.377
5.907ThrIle: 5.907 ± 4.511
7.22ThrLys: 7.22 ± 0.675
5.251ThrLeu: 5.251 ± 1.237
3.282ThrMet: 3.282 ± 0.619
1.969ThrAsn: 1.969 ± 0.721
3.282ThrPro: 3.282 ± 1.135
3.61ThrGln: 3.61 ± 0.948
2.297ThrArg: 2.297 ± 0.503
4.266ThrSer: 4.266 ± 0.851
4.595ThrThr: 4.595 ± 2.164
5.579ThrVal: 5.579 ± 0.375
0.328ThrTrp: 0.328 ± 0.145
4.923ThrTyr: 4.923 ± 0.882
0.0ThrXaa: 0.0 ± 0.0
Val
4.923ValAla: 4.923 ± 0.929
1.313ValCys: 1.313 ± 0.581
5.907ValAsp: 5.907 ± 0.851
3.61ValGlu: 3.61 ± 0.503
2.626ValPhe: 2.626 ± 0.639
2.297ValGly: 2.297 ± 0.65
2.954ValHis: 2.954 ± 0.595
2.954ValIle: 2.954 ± 1.307
7.877ValLys: 7.877 ± 0.199
2.954ValLeu: 2.954 ± 0.595
2.954ValMet: 2.954 ± 1.918
4.595ValAsn: 4.595 ± 1.007
2.297ValPro: 2.297 ± 0.48
0.328ValGln: 0.328 ± 0.145
2.297ValArg: 2.297 ± 0.574
5.251ValSer: 5.251 ± 2.323
3.61ValThr: 3.61 ± 0.503
5.907ValVal: 5.907 ± 1.517
0.656ValTrp: 0.656 ± 0.29
5.579ValTyr: 5.579 ± 1.853
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.985TrpAsp: 0.985 ± 0.436
0.328TrpGlu: 0.328 ± 0.145
0.656TrpPhe: 0.656 ± 0.755
0.0TrpGly: 0.0 ± 0.0
0.328TrpHis: 0.328 ± 0.145
0.656TrpIle: 0.656 ± 0.458
0.0TrpLys: 0.0 ± 0.0
1.313TrpLeu: 1.313 ± 0.303
0.328TrpMet: 0.328 ± 0.512
0.328TrpAsn: 0.328 ± 0.145
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.656TrpArg: 0.656 ± 0.29
0.328TrpSer: 0.328 ± 0.145
0.0TrpThr: 0.0 ± 0.0
0.328TrpVal: 0.328 ± 0.863
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.297TyrAla: 2.297 ± 0.48
0.985TyrCys: 0.985 ± 0.36
7.22TyrAsp: 7.22 ± 0.578
2.954TyrGlu: 2.954 ± 1.307
4.595TyrPhe: 4.595 ± 1.533
2.626TyrGly: 2.626 ± 0.639
4.266TyrHis: 4.266 ± 2.589
4.266TyrIle: 4.266 ± 2.111
2.954TyrLys: 2.954 ± 0.727
4.266TyrLeu: 4.266 ± 0.851
3.938TyrMet: 3.938 ± 0.754
2.626TyrAsn: 2.626 ± 0.601
1.641TyrPro: 1.641 ± 0.31
1.641TyrGln: 1.641 ± 0.771
2.954TyrArg: 2.954 ± 0.727
4.266TyrSer: 4.266 ± 0.919
5.907TyrThr: 5.907 ± 2.39
5.251TyrVal: 5.251 ± 1.212
0.328TyrTrp: 0.328 ± 0.577
3.61TyrTyr: 3.61 ± 0.279
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3048 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski