Amino acid dipepetide frequency for Imtechella halotolerans K1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.324AlaAla: 4.324 ± 0.084	0.582AlaCys: 0.582 ± 0.025	3.08AlaAsp: 3.08 ± 0.065	3.786AlaGlu: 3.786 ± 0.072	3.266AlaPhe: 3.266 ± 0.063	3.936AlaGly: 3.936 ± 0.079	1.257AlaHis: 1.257 ± 0.043	5.572AlaIle: 5.572 ± 0.075	4.158AlaLys: 4.158 ± 0.079	6.447AlaLeu: 6.447 ± 0.086	1.625AlaMet: 1.625 ± 0.043	3.178AlaAsn: 3.178 ± 0.06	1.945AlaPro: 1.945 ± 0.047	2.676AlaGln: 2.676 ± 0.064	2.139AlaArg: 2.139 ± 0.05	4.366AlaSer: 4.366 ± 0.072	3.845AlaThr: 3.845 ± 0.074	4.144AlaVal: 4.144 ± 0.073	0.67AlaTrp: 0.67 ± 0.031	2.686AlaTyr: 2.686 ± 0.062	0.0AlaXaa: 0.0 ± 0.0
Cys	0.43CysAla: 0.43 ± 0.02	0.08CysCys: 0.08 ± 0.01	0.38CysAsp: 0.38 ± 0.022	0.442CysGlu: 0.442 ± 0.027	0.379CysPhe: 0.379 ± 0.02	0.587CysGly: 0.587 ± 0.025	0.184CysHis: 0.184 ± 0.018	0.539CysIle: 0.539 ± 0.026	0.395CysLys: 0.395 ± 0.022	0.59CysLeu: 0.59 ± 0.024	0.163CysMet: 0.163 ± 0.014	0.368CysAsn: 0.368 ± 0.02	0.282CysPro: 0.282 ± 0.021	0.234CysGln: 0.234 ± 0.017	0.2CysArg: 0.2 ± 0.014	0.499CysSer: 0.499 ± 0.025	0.422CysThr: 0.422 ± 0.021	0.417CysVal: 0.417 ± 0.021	0.072CysTrp: 0.072 ± 0.008	0.274CysTyr: 0.274 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.509AspAla: 3.509 ± 0.076	0.346AspCys: 0.346 ± 0.023	2.411AspAsp: 2.411 ± 0.058	3.406AspGlu: 3.406 ± 0.061	3.379AspPhe: 3.379 ± 0.062	3.446AspGly: 3.446 ± 0.081	0.929AspHis: 0.929 ± 0.035	4.202AspIle: 4.202 ± 0.07	3.651AspLys: 3.651 ± 0.074	4.56AspLeu: 4.56 ± 0.074	1.164AspMet: 1.164 ± 0.042	2.794AspAsn: 2.794 ± 0.057	1.724AspPro: 1.724 ± 0.048	1.648AspGln: 1.648 ± 0.039	2.021AspArg: 2.021 ± 0.045	3.301AspSer: 3.301 ± 0.065	2.751AspThr: 2.751 ± 0.051	3.449AspVal: 3.449 ± 0.074	0.716AspTrp: 0.716 ± 0.032	2.583AspTyr: 2.583 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	4.494GluAla: 4.494 ± 0.083	0.331GluCys: 0.331 ± 0.022	3.351GluAsp: 3.351 ± 0.062	4.896GluGlu: 4.896 ± 0.1	2.799GluPhe: 2.799 ± 0.056	3.919GluGly: 3.919 ± 0.07	1.21GluHis: 1.21 ± 0.038	5.478GluIle: 5.478 ± 0.089	5.239GluLys: 5.239 ± 0.083	6.511GluLeu: 6.511 ± 0.089	1.709GluMet: 1.709 ± 0.046	4.197GluAsn: 4.197 ± 0.076	1.568GluPro: 1.568 ± 0.044	2.425GluGln: 2.425 ± 0.059	2.769GluArg: 2.769 ± 0.06	3.573GluSer: 3.573 ± 0.062	3.512GluThr: 3.512 ± 0.063	4.777GluVal: 4.777 ± 0.082	0.598GluTrp: 0.598 ± 0.027	2.428GluTyr: 2.428 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	2.796PheAla: 2.796 ± 0.053	0.368PheCys: 0.368 ± 0.019	2.944PheAsp: 2.944 ± 0.062	3.15PheGlu: 3.15 ± 0.051	2.626PhePhe: 2.626 ± 0.063	3.476PheGly: 3.476 ± 0.062	0.893PheHis: 0.893 ± 0.031	3.906PheIle: 3.906 ± 0.076	3.451PheLys: 3.451 ± 0.073	4.597PheLeu: 4.597 ± 0.093	1.26PheMet: 1.26 ± 0.042	3.183PheAsn: 3.183 ± 0.062	1.854PhePro: 1.854 ± 0.048	1.726PheGln: 1.726 ± 0.045	1.628PheArg: 1.628 ± 0.041	4.08PheSer: 4.08 ± 0.075	3.256PheThr: 3.256 ± 0.065	2.961PheVal: 2.961 ± 0.064	0.587PheTrp: 0.587 ± 0.028	2.165PheTyr: 2.165 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.157GlyAla: 4.157 ± 0.076	0.603GlyCys: 0.603 ± 0.039	3.161GlyAsp: 3.161 ± 0.068	3.622GlyGlu: 3.622 ± 0.072	3.605GlyPhe: 3.605 ± 0.066	4.492GlyGly: 4.492 ± 0.1	1.213GlyHis: 1.213 ± 0.045	5.627GlyIle: 5.627 ± 0.09	4.787GlyLys: 4.787 ± 0.079	5.541GlyLeu: 5.541 ± 0.085	1.864GlyMet: 1.864 ± 0.047	3.694GlyAsn: 3.694 ± 0.072	1.394GlyPro: 1.394 ± 0.046	1.975GlyGln: 1.975 ± 0.05	2.22GlyArg: 2.22 ± 0.06	4.134GlySer: 4.134 ± 0.09	3.969GlyThr: 3.969 ± 0.089	4.587GlyVal: 4.587 ± 0.085	0.817GlyTrp: 0.817 ± 0.033	3.066GlyTyr: 3.066 ± 0.072	0.0GlyXaa: 0.0 ± 0.0
His	1.029HisAla: 1.029 ± 0.034	0.18HisCys: 0.18 ± 0.016	0.892HisAsp: 0.892 ± 0.031	1.046HisGlu: 1.046 ± 0.035	1.274HisPhe: 1.274 ± 0.036	1.197HisGly: 1.197 ± 0.034	0.527HisHis: 0.527 ± 0.028	1.584HisIle: 1.584 ± 0.044	1.331HisLys: 1.331 ± 0.04	1.999HisLeu: 1.999 ± 0.048	0.419HisMet: 0.419 ± 0.023	0.961HisAsn: 0.961 ± 0.03	1.028HisPro: 1.028 ± 0.037	0.857HisGln: 0.857 ± 0.033	0.778HisArg: 0.778 ± 0.03	1.277HisSer: 1.277 ± 0.042	1.094HisThr: 1.094 ± 0.035	0.982HisVal: 0.982 ± 0.034	0.266HisTrp: 0.266 ± 0.015	0.96HisTyr: 0.96 ± 0.036	0.0HisXaa: 0.0 ± 0.0
Ile	5.788IleAla: 5.788 ± 0.087	0.517IleCys: 0.517 ± 0.024	4.714IleAsp: 4.714 ± 0.076	5.579IleGlu: 5.579 ± 0.081	3.397IlePhe: 3.397 ± 0.065	5.177IleGly: 5.177 ± 0.087	1.589IleHis: 1.589 ± 0.045	5.687IleIle: 5.687 ± 0.094	5.187IleLys: 5.187 ± 0.074	7.033IleLeu: 7.033 ± 0.104	1.448IleMet: 1.448 ± 0.038	4.408IleAsn: 4.408 ± 0.078	3.489IlePro: 3.489 ± 0.066	2.826IleGln: 2.826 ± 0.053	2.803IleArg: 2.803 ± 0.056	5.701IleSer: 5.701 ± 0.091	4.992IleThr: 4.992 ± 0.097	4.836IleVal: 4.836 ± 0.066	0.687IleTrp: 0.687 ± 0.029	2.751IleTyr: 2.751 ± 0.062	0.0IleXaa: 0.0 ± 0.0
Lys	4.724LysAla: 4.724 ± 0.089	0.313LysCys: 0.313 ± 0.02	3.918LysAsp: 3.918 ± 0.08	6.109LysGlu: 6.109 ± 0.088	2.46LysPhe: 2.46 ± 0.052	4.579LysGly: 4.579 ± 0.077	1.387LysHis: 1.387 ± 0.04	5.253LysIle: 5.253 ± 0.075	5.77LysLys: 5.77 ± 0.092	6.093LysLeu: 6.093 ± 0.089	1.872LysMet: 1.872 ± 0.045	4.632LysAsn: 4.632 ± 0.079	2.22LysPro: 2.22 ± 0.048	2.645LysGln: 2.645 ± 0.056	2.982LysArg: 2.982 ± 0.066	4.147LysSer: 4.147 ± 0.069	4.1LysThr: 4.1 ± 0.064	4.505LysVal: 4.505 ± 0.075	0.805LysTrp: 0.805 ± 0.033	2.753LysTyr: 2.753 ± 0.06	0.0LysXaa: 0.0 ± 0.0
Leu	5.922LeuAla: 5.922 ± 0.107	0.683LeuCys: 0.683 ± 0.03	4.849LeuAsp: 4.849 ± 0.07	6.214LeuGlu: 6.214 ± 0.092	4.931LeuPhe: 4.931 ± 0.098	5.909LeuGly: 5.909 ± 0.089	1.828LeuHis: 1.828 ± 0.045	6.808LeuIle: 6.808 ± 0.098	7.167LeuLys: 7.167 ± 0.101	9.581LeuLeu: 9.581 ± 0.142	2.283LeuMet: 2.283 ± 0.057	5.251LeuAsn: 5.251 ± 0.081	3.791LeuPro: 3.791 ± 0.075	3.629LeuGln: 3.629 ± 0.054	3.566LeuArg: 3.566 ± 0.06	6.898LeuSer: 6.898 ± 0.105	5.36LeuThr: 5.36 ± 0.079	5.585LeuVal: 5.585 ± 0.088	0.934LeuTrp: 0.934 ± 0.037	3.427LeuTyr: 3.427 ± 0.065	0.0LeuXaa: 0.0 ± 0.0
Met	1.838MetAla: 1.838 ± 0.048	0.136MetCys: 0.136 ± 0.012	1.291MetAsp: 1.291 ± 0.036	1.63MetGlu: 1.63 ± 0.043	0.9MetPhe: 0.9 ± 0.029	1.532MetGly: 1.532 ± 0.045	0.461MetHis: 0.461 ± 0.022	1.631MetIle: 1.631 ± 0.04	2.157MetLys: 2.157 ± 0.048	2.171MetLeu: 2.171 ± 0.054	0.612MetMet: 0.612 ± 0.03	1.391MetAsn: 1.391 ± 0.035	0.902MetPro: 0.902 ± 0.032	0.901MetGln: 0.901 ± 0.033	0.986MetArg: 0.986 ± 0.037	1.482MetSer: 1.482 ± 0.038	1.158MetThr: 1.158 ± 0.034	1.555MetVal: 1.555 ± 0.045	0.166MetTrp: 0.166 ± 0.013	0.871MetTyr: 0.871 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.616AsnAla: 3.616 ± 0.063	0.384AsnCys: 0.384 ± 0.021	2.954AsnAsp: 2.954 ± 0.068	3.692AsnGlu: 3.692 ± 0.071	2.815AsnPhe: 2.815 ± 0.068	3.949AsnGly: 3.949 ± 0.081	1.15AsnHis: 1.15 ± 0.033	4.116AsnIle: 4.116 ± 0.083	3.727AsnLys: 3.727 ± 0.066	4.846AsnLeu: 4.846 ± 0.081	1.28AsnMet: 1.28 ± 0.038	3.414AsnAsn: 3.414 ± 0.079	2.734AsnPro: 2.734 ± 0.061	2.304AsnGln: 2.304 ± 0.046	2.332AsnArg: 2.332 ± 0.053	3.854AsnSer: 3.854 ± 0.076	3.555AsnThr: 3.555 ± 0.073	3.43AsnVal: 3.43 ± 0.07	0.738AsnTrp: 0.738 ± 0.029	2.681AsnTyr: 2.681 ± 0.064	0.0AsnXaa: 0.0 ± 0.0
Pro	1.905ProAla: 1.905 ± 0.05	0.192ProCys: 0.192 ± 0.013	1.96ProAsp: 1.96 ± 0.05	2.891ProGlu: 2.891 ± 0.062	1.93ProPhe: 1.93 ± 0.046	2.085ProGly: 2.085 ± 0.049	0.682ProHis: 0.682 ± 0.029	2.917ProIle: 2.917 ± 0.062	2.486ProLys: 2.486 ± 0.061	3.231ProLeu: 3.231 ± 0.063	0.832ProMet: 0.832 ± 0.031	2.138ProAsn: 2.138 ± 0.052	0.868ProPro: 0.868 ± 0.036	1.307ProGln: 1.307 ± 0.039	1.003ProArg: 1.003 ± 0.031	2.422ProSer: 2.422 ± 0.054	2.079ProThr: 2.079 ± 0.043	2.407ProVal: 2.407 ± 0.046	0.362ProTrp: 0.362 ± 0.021	1.546ProTyr: 1.546 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.274GlnAla: 2.274 ± 0.051	0.186GlnCys: 0.186 ± 0.015	1.595GlnAsp: 1.595 ± 0.044	2.669GlnGlu: 2.669 ± 0.058	1.738GlnPhe: 1.738 ± 0.043	2.215GlnGly: 2.215 ± 0.052	0.718GlnHis: 0.718 ± 0.031	2.63GlnIle: 2.63 ± 0.047	2.784GlnLys: 2.784 ± 0.058	4.19GlnLeu: 4.19 ± 0.083	0.945GlnMet: 0.945 ± 0.035	2.063GlnAsn: 2.063 ± 0.053	1.244GlnPro: 1.244 ± 0.033	1.78GlnGln: 1.78 ± 0.05	1.6GlnArg: 1.6 ± 0.044	2.163GlnSer: 2.163 ± 0.054	1.936GlnThr: 1.936 ± 0.042	2.164GlnVal: 2.164 ± 0.048	0.494GlnTrp: 0.494 ± 0.021	1.567GlnTyr: 1.567 ± 0.044	0.0GlnXaa: 0.0 ± 0.0
Arg	2.164ArgAla: 2.164 ± 0.048	0.193ArgCys: 0.193 ± 0.016	1.84ArgAsp: 1.84 ± 0.055	2.367ArgGlu: 2.367 ± 0.06	2.143ArgPhe: 2.143 ± 0.047	2.061ArgGly: 2.061 ± 0.05	0.703ArgHis: 0.703 ± 0.032	3.35ArgIle: 3.35 ± 0.058	2.845ArgLys: 2.845 ± 0.059	3.59ArgLeu: 3.59 ± 0.067	1.046ArgMet: 1.046 ± 0.034	2.324ArgAsn: 2.324 ± 0.059	1.229ArgPro: 1.229 ± 0.043	1.19ArgGln: 1.19 ± 0.034	1.468ArgArg: 1.468 ± 0.041	2.084ArgSer: 2.084 ± 0.048	1.964ArgThr: 1.964 ± 0.053	2.269ArgVal: 2.269 ± 0.051	0.482ArgTrp: 0.482 ± 0.024	1.723ArgTyr: 1.723 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	3.58SerAla: 3.58 ± 0.062	0.598SerCys: 0.598 ± 0.03	3.307SerAsp: 3.307 ± 0.069	4.039SerGlu: 4.039 ± 0.068	3.814SerPhe: 3.814 ± 0.065	4.564SerGly: 4.564 ± 0.087	1.336SerHis: 1.336 ± 0.042	5.633SerIle: 5.633 ± 0.097	4.702SerLys: 4.702 ± 0.075	6.511SerLeu: 6.511 ± 0.099	1.53SerMet: 1.53 ± 0.038	3.81SerAsn: 3.81 ± 0.067	2.214SerPro: 2.214 ± 0.052	2.487SerGln: 2.487 ± 0.058	2.312SerArg: 2.312 ± 0.055	4.579SerSer: 4.579 ± 0.099	3.664SerThr: 3.664 ± 0.072	4.093SerVal: 4.093 ± 0.074	0.786SerTrp: 0.786 ± 0.035	3.095SerTyr: 3.095 ± 0.066	0.0SerXaa: 0.0 ± 0.0
Thr	3.767ThrAla: 3.767 ± 0.076	0.327ThrCys: 0.327 ± 0.021	2.98ThrAsp: 2.98 ± 0.069	3.205ThrGlu: 3.205 ± 0.07	3.046ThrPhe: 3.046 ± 0.052	3.877ThrGly: 3.877 ± 0.076	1.194ThrHis: 1.194 ± 0.038	5.101ThrIle: 5.101 ± 0.085	3.564ThrLys: 3.564 ± 0.07	5.822ThrLeu: 5.822 ± 0.075	1.041ThrMet: 1.041 ± 0.038	3.133ThrAsn: 3.133 ± 0.069	2.623ThrPro: 2.623 ± 0.052	2.224ThrGln: 2.224 ± 0.052	1.799ThrArg: 1.799 ± 0.047	3.948ThrSer: 3.948 ± 0.08	3.622ThrThr: 3.622 ± 0.075	3.708ThrVal: 3.708 ± 0.072	0.52ThrTrp: 0.52 ± 0.026	2.606ThrTyr: 2.606 ± 0.071	0.0ThrXaa: 0.0 ± 0.0
Val	4.231ValAla: 4.231 ± 0.073	0.5ValCys: 0.5 ± 0.025	3.416ValAsp: 3.416 ± 0.063	3.842ValGlu: 3.842 ± 0.07	3.326ValPhe: 3.326 ± 0.074	3.974ValGly: 3.974 ± 0.076	1.192ValHis: 1.192 ± 0.033	4.821ValIle: 4.821 ± 0.078	4.167ValLys: 4.167 ± 0.071	6.252ValLeu: 6.252 ± 0.1	1.476ValMet: 1.476 ± 0.045	3.356ValAsn: 3.356 ± 0.063	2.258ValPro: 2.258 ± 0.055	2.032ValGln: 2.032 ± 0.049	2.203ValArg: 2.203 ± 0.051	4.774ValSer: 4.774 ± 0.064	3.78ValThr: 3.78 ± 0.085	4.586ValVal: 4.586 ± 0.094	0.637ValTrp: 0.637 ± 0.027	2.598ValTyr: 2.598 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	0.615TrpAla: 0.615 ± 0.027	0.104TrpCys: 0.104 ± 0.01	0.631TrpAsp: 0.631 ± 0.03	0.744TrpGlu: 0.744 ± 0.031	0.603TrpPhe: 0.603 ± 0.027	0.699TrpGly: 0.699 ± 0.03	0.243TrpHis: 0.243 ± 0.016	0.851TrpIle: 0.851 ± 0.037	0.854TrpLys: 0.854 ± 0.034	1.012TrpLeu: 1.012 ± 0.034	0.334TrpMet: 0.334 ± 0.018	0.735TrpAsn: 0.735 ± 0.033	0.276TrpPro: 0.276 ± 0.022	0.398TrpGln: 0.398 ± 0.023	0.424TrpArg: 0.424 ± 0.021	0.66TrpSer: 0.66 ± 0.029	0.5TrpThr: 0.5 ± 0.027	0.663TrpVal: 0.663 ± 0.032	0.152TrpTrp: 0.152 ± 0.012	0.498TrpTyr: 0.498 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.52TyrAla: 2.52 ± 0.056	0.316TyrCys: 0.316 ± 0.017	2.313TyrAsp: 2.313 ± 0.056	2.456TyrGlu: 2.456 ± 0.058	2.472TyrPhe: 2.472 ± 0.052	2.854TyrGly: 2.854 ± 0.064	0.985TyrHis: 0.985 ± 0.037	2.902TyrIle: 2.902 ± 0.056	2.845TyrLys: 2.845 ± 0.06	4.039TyrLeu: 4.039 ± 0.074	0.871TyrMet: 0.871 ± 0.03	2.541TyrAsn: 2.541 ± 0.061	1.599TyrPro: 1.599 ± 0.041	1.692TyrGln: 1.692 ± 0.047	1.8TyrArg: 1.8 ± 0.048	2.712TyrSer: 2.712 ± 0.062	2.547TyrThr: 2.547 ± 0.066	2.303TyrVal: 2.303 ± 0.06	0.51TyrTrp: 0.51 ± 0.025	1.962TyrTyr: 1.962 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2694 proteins (933156 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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