Amino acid dipepetide frequency for Jeotgalibacillus soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.735AlaAla: 6.735 ± 0.112
0.566AlaCys: 0.566 ± 0.025
3.476AlaAsp: 3.476 ± 0.054
4.957AlaGlu: 4.957 ± 0.085
3.495AlaPhe: 3.495 ± 0.06
5.777AlaGly: 5.777 ± 0.083
1.449AlaHis: 1.449 ± 0.04
5.989AlaIle: 5.989 ± 0.087
4.301AlaLys: 4.301 ± 0.067
7.477AlaLeu: 7.477 ± 0.084
2.179AlaMet: 2.179 ± 0.045
2.687AlaAsn: 2.687 ± 0.062
2.154AlaPro: 2.154 ± 0.052
2.335AlaGln: 2.335 ± 0.044
2.796AlaArg: 2.796 ± 0.052
4.5AlaSer: 4.5 ± 0.062
3.347AlaThr: 3.347 ± 0.06
5.737AlaVal: 5.737 ± 0.082
0.631AlaTrp: 0.631 ± 0.024
2.233AlaTyr: 2.233 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
0.39CysAla: 0.39 ± 0.019
0.084CysCys: 0.084 ± 0.009
0.352CysAsp: 0.352 ± 0.018
0.447CysGlu: 0.447 ± 0.021
0.286CysPhe: 0.286 ± 0.02
0.613CysGly: 0.613 ± 0.023
0.201CysHis: 0.201 ± 0.014
0.449CysIle: 0.449 ± 0.022
0.316CysLys: 0.316 ± 0.018
0.655CysLeu: 0.655 ± 0.027
0.172CysMet: 0.172 ± 0.014
0.241CysAsn: 0.241 ± 0.015
0.327CysPro: 0.327 ± 0.02
0.251CysGln: 0.251 ± 0.015
0.307CysArg: 0.307 ± 0.017
0.462CysSer: 0.462 ± 0.023
0.365CysThr: 0.365 ± 0.022
0.402CysVal: 0.402 ± 0.018
0.061CysTrp: 0.061 ± 0.007
0.22CysTyr: 0.22 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
3.375AspAla: 3.375 ± 0.057
0.345AspCys: 0.345 ± 0.02
2.466AspAsp: 2.466 ± 0.051
4.428AspGlu: 4.428 ± 0.074
2.306AspPhe: 2.306 ± 0.054
3.47AspGly: 3.47 ± 0.059
1.42AspHis: 1.42 ± 0.036
3.927AspIle: 3.927 ± 0.066
2.653AspLys: 2.653 ± 0.055
5.142AspLeu: 5.142 ± 0.07
1.335AspMet: 1.335 ± 0.035
1.629AspAsn: 1.629 ± 0.04
2.239AspPro: 2.239 ± 0.049
2.461AspGln: 2.461 ± 0.056
2.684AspArg: 2.684 ± 0.054
2.64AspSer: 2.64 ± 0.052
2.372AspThr: 2.372 ± 0.05
3.679AspVal: 3.679 ± 0.065
0.65AspTrp: 0.65 ± 0.025
2.008AspTyr: 2.008 ± 0.048
0.0AspXaa: 0.0 ± 0.0
Glu
5.818GluAla: 5.818 ± 0.075
0.342GluCys: 0.342 ± 0.018
3.917GluAsp: 3.917 ± 0.069
7.459GluGlu: 7.459 ± 0.106
2.436GluPhe: 2.436 ± 0.045
4.648GluGly: 4.648 ± 0.062
1.527GluHis: 1.527 ± 0.039
5.671GluIle: 5.671 ± 0.08
6.16GluLys: 6.16 ± 0.091
7.413GluLeu: 7.413 ± 0.081
2.422GluMet: 2.422 ± 0.044
3.532GluAsn: 3.532 ± 0.06
2.053GluPro: 2.053 ± 0.052
3.653GluGln: 3.653 ± 0.069
3.847GluArg: 3.847 ± 0.06
3.64GluSer: 3.64 ± 0.058
3.749GluThr: 3.749 ± 0.061
5.104GluVal: 5.104 ± 0.079
0.965GluTrp: 0.965 ± 0.03
2.142GluTyr: 2.142 ± 0.049
0.0GluXaa: 0.0 ± 0.0
Phe
2.962PheAla: 2.962 ± 0.058
0.327PheCys: 0.327 ± 0.02
2.475PheAsp: 2.475 ± 0.054
2.791PheGlu: 2.791 ± 0.052
2.314PhePhe: 2.314 ± 0.066
3.317PheGly: 3.317 ± 0.06
1.009PheHis: 1.009 ± 0.033
3.825PheIle: 3.825 ± 0.075
2.151PheLys: 2.151 ± 0.044
4.4PheLeu: 4.4 ± 0.088
1.249PheMet: 1.249 ± 0.037
1.88PheAsn: 1.88 ± 0.043
1.71PhePro: 1.71 ± 0.043
1.591PheGln: 1.591 ± 0.04
1.547PheArg: 1.547 ± 0.038
3.307PheSer: 3.307 ± 0.057
2.584PheThr: 2.584 ± 0.058
3.12PheVal: 3.12 ± 0.055
0.474PheTrp: 0.474 ± 0.025
1.657PheTyr: 1.657 ± 0.043
0.0PheXaa: 0.0 ± 0.0
Gly
5.153GlyAla: 5.153 ± 0.086
0.576GlyCys: 0.576 ± 0.026
3.35GlyAsp: 3.35 ± 0.062
4.702GlyGlu: 4.702 ± 0.065
3.439GlyPhe: 3.439 ± 0.06
5.049GlyGly: 5.049 ± 0.089
1.478GlyHis: 1.478 ± 0.037
6.075GlyIle: 6.075 ± 0.09
4.507GlyLys: 4.507 ± 0.068
6.777GlyLeu: 6.777 ± 0.092
2.208GlyMet: 2.208 ± 0.049
2.6GlyAsn: 2.6 ± 0.051
1.835GlyPro: 1.835 ± 0.04
2.317GlyGln: 2.317 ± 0.052
2.811GlyArg: 2.811 ± 0.056
4.126GlySer: 4.126 ± 0.064
4.022GlyThr: 4.022 ± 0.072
5.197GlyVal: 5.197 ± 0.09
0.839GlyTrp: 0.839 ± 0.03
2.715GlyTyr: 2.715 ± 0.065
0.0GlyXaa: 0.0 ± 0.0
His
1.491HisAla: 1.491 ± 0.038
0.215HisCys: 0.215 ± 0.017
1.133HisAsp: 1.133 ± 0.035
1.549HisGlu: 1.549 ± 0.043
1.133HisPhe: 1.133 ± 0.032
1.422HisGly: 1.422 ± 0.033
0.728HisHis: 0.728 ± 0.033
1.532HisIle: 1.532 ± 0.034
1.031HisLys: 1.031 ± 0.034
2.221HisLeu: 2.221 ± 0.048
0.514HisMet: 0.514 ± 0.021
0.736HisAsn: 0.736 ± 0.031
1.185HisPro: 1.185 ± 0.038
0.969HisGln: 0.969 ± 0.033
0.938HisArg: 0.938 ± 0.032
1.351HisSer: 1.351 ± 0.036
1.108HisThr: 1.108 ± 0.035
1.536HisVal: 1.536 ± 0.039
0.236HisTrp: 0.236 ± 0.016
0.899HisTyr: 0.899 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
6.138IleAla: 6.138 ± 0.08
0.574IleCys: 0.574 ± 0.022
4.364IleAsp: 4.364 ± 0.068
6.123IleGlu: 6.123 ± 0.083
3.265IlePhe: 3.265 ± 0.066
6.075IleGly: 6.075 ± 0.089
1.766IleHis: 1.766 ± 0.046
5.949IleIle: 5.949 ± 0.088
4.31IleLys: 4.31 ± 0.071
6.951IleLeu: 6.951 ± 0.094
1.972IleMet: 1.972 ± 0.054
3.258IleAsn: 3.258 ± 0.058
3.4IlePro: 3.4 ± 0.055
3.3IleGln: 3.3 ± 0.062
3.241IleArg: 3.241 ± 0.057
5.004IleSer: 5.004 ± 0.077
4.34IleThr: 4.34 ± 0.063
5.666IleVal: 5.666 ± 0.078
0.638IleTrp: 0.638 ± 0.025
2.231IleTyr: 2.231 ± 0.046
0.0IleXaa: 0.0 ± 0.0
Lys
4.391LysAla: 4.391 ± 0.071
0.258LysCys: 0.258 ± 0.015
3.356LysAsp: 3.356 ± 0.067
6.49LysGlu: 6.49 ± 0.079
1.546LysPhe: 1.546 ± 0.038
4.224LysGly: 4.224 ± 0.067
1.268LysHis: 1.268 ± 0.033
4.32LysIle: 4.32 ± 0.062
5.532LysLys: 5.532 ± 0.086
5.049LysLeu: 5.049 ± 0.079
2.135LysMet: 2.135 ± 0.049
3.085LysAsn: 3.085 ± 0.049
2.065LysPro: 2.065 ± 0.042
2.754LysGln: 2.754 ± 0.059
3.236LysArg: 3.236 ± 0.054
3.161LysSer: 3.161 ± 0.054
3.26LysThr: 3.26 ± 0.057
3.933LysVal: 3.933 ± 0.064
0.829LysTrp: 0.829 ± 0.028
1.727LysTyr: 1.727 ± 0.041
0.0LysXaa: 0.0 ± 0.0
Leu
7.395LeuAla: 7.395 ± 0.092
0.613LeuCys: 0.613 ± 0.023
4.828LeuAsp: 4.828 ± 0.071
6.712LeuGlu: 6.712 ± 0.093
4.808LeuPhe: 4.808 ± 0.088
6.316LeuGly: 6.316 ± 0.089
2.063LeuHis: 2.063 ± 0.048
7.281LeuIle: 7.281 ± 0.101
6.02LeuLys: 6.02 ± 0.086
10.232LeuLeu: 10.232 ± 0.122
2.651LeuMet: 2.651 ± 0.057
4.185LeuAsn: 4.185 ± 0.068
4.005LeuPro: 4.005 ± 0.06
3.599LeuGln: 3.599 ± 0.066
3.779LeuArg: 3.779 ± 0.055
7.112LeuSer: 7.112 ± 0.09
5.648LeuThr: 5.648 ± 0.07
6.262LeuVal: 6.262 ± 0.073
0.841LeuTrp: 0.841 ± 0.031
3.091LeuTyr: 3.091 ± 0.06
0.0LeuXaa: 0.0 ± 0.0
Met
2.15MetAla: 2.15 ± 0.043
0.141MetCys: 0.141 ± 0.012
1.631MetAsp: 1.631 ± 0.041
2.194MetGlu: 2.194 ± 0.046
1.077MetPhe: 1.077 ± 0.033
1.858MetGly: 1.858 ± 0.04
0.463MetHis: 0.463 ± 0.021
2.42MetIle: 2.42 ± 0.052
2.43MetLys: 2.43 ± 0.047
2.718MetLeu: 2.718 ± 0.052
1.009MetMet: 1.009 ± 0.035
1.632MetAsn: 1.632 ± 0.037
1.036MetPro: 1.036 ± 0.035
0.928MetGln: 0.928 ± 0.03
1.125MetArg: 1.125 ± 0.035
1.758MetSer: 1.758 ± 0.041
1.831MetThr: 1.831 ± 0.038
1.884MetVal: 1.884 ± 0.039
0.211MetTrp: 0.211 ± 0.013
0.723MetTyr: 0.723 ± 0.025
0.0MetXaa: 0.0 ± 0.0
Asn
2.759AsnAla: 2.759 ± 0.057
0.27AsnCys: 0.27 ± 0.015
2.223AsnAsp: 2.223 ± 0.046
3.691AsnGlu: 3.691 ± 0.056
1.45AsnPhe: 1.45 ± 0.04
3.347AsnGly: 3.347 ± 0.061
1.068AsnHis: 1.068 ± 0.027
3.118AsnIle: 3.118 ± 0.059
2.555AsnLys: 2.555 ± 0.052
3.562AsnLeu: 3.562 ± 0.06
1.21AsnMet: 1.21 ± 0.036
1.819AsnAsn: 1.819 ± 0.051
2.009AsnPro: 2.009 ± 0.04
1.877AsnGln: 1.877 ± 0.042
2.07AsnArg: 2.07 ± 0.043
2.173AsnSer: 2.173 ± 0.054
2.021AsnThr: 2.021 ± 0.045
3.029AsnVal: 3.029 ± 0.058
0.483AsnTrp: 0.483 ± 0.023
1.302AsnTyr: 1.302 ± 0.037
0.0AsnXaa: 0.0 ± 0.0
Pro
2.618ProAla: 2.618 ± 0.046
0.21ProCys: 0.21 ± 0.014
2.097ProAsp: 2.097 ± 0.049
2.951ProGlu: 2.951 ± 0.062
2.081ProPhe: 2.081 ± 0.048
2.371ProGly: 2.371 ± 0.05
0.833ProHis: 0.833 ± 0.029
2.961ProIle: 2.961 ± 0.053
1.932ProLys: 1.932 ± 0.043
3.673ProLeu: 3.673 ± 0.062
0.915ProMet: 0.915 ± 0.027
1.676ProAsn: 1.676 ± 0.04
1.088ProPro: 1.088 ± 0.038
1.056ProGln: 1.056 ± 0.03
1.181ProArg: 1.181 ± 0.038
2.549ProSer: 2.549 ± 0.048
1.869ProThr: 1.869 ± 0.043
2.978ProVal: 2.978 ± 0.058
0.358ProTrp: 0.358 ± 0.018
1.393ProTyr: 1.393 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
3.024GlnAla: 3.024 ± 0.055
0.226GlnCys: 0.226 ± 0.016
1.764GlnAsp: 1.764 ± 0.043
2.987GlnGlu: 2.987 ± 0.057
1.629GlnPhe: 1.629 ± 0.038
2.369GlnGly: 2.369 ± 0.049
0.879GlnHis: 0.879 ± 0.028
2.596GlnIle: 2.596 ± 0.059
2.523GlnLys: 2.523 ± 0.049
4.143GlnLeu: 4.143 ± 0.071
1.231GlnMet: 1.231 ± 0.031
1.581GlnAsn: 1.581 ± 0.039
1.327GlnPro: 1.327 ± 0.041
2.015GlnGln: 2.015 ± 0.049
1.644GlnArg: 1.644 ± 0.046
2.463GlnSer: 2.463 ± 0.047
2.027GlnThr: 2.027 ± 0.047
2.423GlnVal: 2.423 ± 0.051
0.472GlnTrp: 0.472 ± 0.021
1.34GlnTyr: 1.34 ± 0.036
0.0GlnXaa: 0.0 ± 0.0
Arg
2.71ArgAla: 2.71 ± 0.047
0.246ArgCys: 0.246 ± 0.015
2.184ArgAsp: 2.184 ± 0.047
3.394ArgGlu: 3.394 ± 0.058
2.057ArgPhe: 2.057 ± 0.046
2.46ArgGly: 2.46 ± 0.052
0.895ArgHis: 0.895 ± 0.026
3.365ArgIle: 3.365 ± 0.059
3.027ArgLys: 3.027 ± 0.055
4.334ArgLeu: 4.334 ± 0.067
1.393ArgMet: 1.393 ± 0.034
1.888ArgAsn: 1.888 ± 0.04
1.428ArgPro: 1.428 ± 0.042
1.694ArgGln: 1.694 ± 0.043
1.914ArgArg: 1.914 ± 0.046
2.561ArgSer: 2.561 ± 0.046
2.119ArgThr: 2.119 ± 0.041
2.876ArgVal: 2.876 ± 0.054
0.412ArgTrp: 0.412 ± 0.023
1.542ArgTyr: 1.542 ± 0.042
0.0ArgXaa: 0.0 ± 0.0
Ser
3.974SerAla: 3.974 ± 0.06
0.412SerCys: 0.412 ± 0.021
2.857SerAsp: 2.857 ± 0.049
3.955SerGlu: 3.955 ± 0.064
3.515SerPhe: 3.515 ± 0.055
4.479SerGly: 4.479 ± 0.066
1.352SerHis: 1.352 ± 0.033
5.51SerIle: 5.51 ± 0.074
3.423SerLys: 3.423 ± 0.054
6.336SerLeu: 6.336 ± 0.083
1.88SerMet: 1.88 ± 0.042
2.45SerAsn: 2.45 ± 0.05
2.286SerPro: 2.286 ± 0.05
2.037SerGln: 2.037 ± 0.043
2.461SerArg: 2.461 ± 0.05
4.514SerSer: 4.514 ± 0.078
3.4SerThr: 3.4 ± 0.055
4.335SerVal: 4.335 ± 0.063
0.613SerTrp: 0.613 ± 0.026
2.138SerTyr: 2.138 ± 0.047
0.0SerXaa: 0.0 ± 0.0
Thr
4.219ThrAla: 4.219 ± 0.074
0.332ThrCys: 0.332 ± 0.017
2.627ThrAsp: 2.627 ± 0.052
3.611ThrGlu: 3.611 ± 0.055
2.552ThrPhe: 2.552 ± 0.053
4.174ThrGly: 4.174 ± 0.067
1.058ThrHis: 1.058 ± 0.033
4.73ThrIle: 4.73 ± 0.07
2.92ThrLys: 2.92 ± 0.062
5.142ThrLeu: 5.142 ± 0.072
1.374ThrMet: 1.374 ± 0.035
2.212ThrAsn: 2.212 ± 0.053
2.291ThrPro: 2.291 ± 0.052
1.491ThrGln: 1.491 ± 0.041
2.016ThrArg: 2.016 ± 0.045
3.354ThrSer: 3.354 ± 0.058
2.846ThrThr: 2.846 ± 0.055
4.198ThrVal: 4.198 ± 0.069
0.479ThrTrp: 0.479 ± 0.024
1.753ThrTyr: 1.753 ± 0.04
0.0ThrXaa: 0.0 ± 0.0
Val
4.914ValAla: 4.914 ± 0.075
0.518ValCys: 0.518 ± 0.025
3.756ValAsp: 3.756 ± 0.064
4.92ValGlu: 4.92 ± 0.075
3.096ValPhe: 3.096 ± 0.051
4.693ValGly: 4.693 ± 0.086
1.45ValHis: 1.45 ± 0.039
5.716ValIle: 5.716 ± 0.075
4.351ValLys: 4.351 ± 0.07
6.955ValLeu: 6.955 ± 0.088
2.121ValMet: 2.121 ± 0.047
3.015ValAsn: 3.015 ± 0.056
2.685ValPro: 2.685 ± 0.042
2.556ValGln: 2.556 ± 0.055
2.859ValArg: 2.859 ± 0.053
4.592ValSer: 4.592 ± 0.074
4.13ValThr: 4.13 ± 0.066
5.066ValVal: 5.066 ± 0.071
0.628ValTrp: 0.628 ± 0.028
2.128ValTyr: 2.128 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
0.576TrpAla: 0.576 ± 0.025
0.081TrpCys: 0.081 ± 0.008
0.502TrpAsp: 0.502 ± 0.025
0.633TrpGlu: 0.633 ± 0.026
0.513TrpPhe: 0.513 ± 0.021
0.699TrpGly: 0.699 ± 0.027
0.226TrpHis: 0.226 ± 0.019
0.898TrpIle: 0.898 ± 0.028
0.722TrpLys: 0.722 ± 0.027
1.141TrpLeu: 1.141 ± 0.036
0.402TrpMet: 0.402 ± 0.023
0.527TrpAsn: 0.527 ± 0.022
0.303TrpPro: 0.303 ± 0.019
0.397TrpGln: 0.397 ± 0.019
0.417TrpArg: 0.417 ± 0.02
0.607TrpSer: 0.607 ± 0.026
0.588TrpThr: 0.588 ± 0.022
0.673TrpVal: 0.673 ± 0.029
0.15TrpTrp: 0.15 ± 0.012
0.32TrpTyr: 0.32 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.03TyrAla: 2.03 ± 0.042
0.266TyrCys: 0.266 ± 0.015
1.868TyrAsp: 1.868 ± 0.041
2.506TyrGlu: 2.506 ± 0.053
1.694TyrPhe: 1.694 ± 0.053
2.415TyrGly: 2.415 ± 0.055
0.796TyrHis: 0.796 ± 0.027
2.231TyrIle: 2.231 ± 0.056
1.758TyrLys: 1.758 ± 0.042
3.123TyrLeu: 3.123 ± 0.064
0.843TyrMet: 0.843 ± 0.027
1.403TyrAsn: 1.403 ± 0.04
1.362TyrPro: 1.362 ± 0.04
1.383TyrGln: 1.383 ± 0.034
1.626TyrArg: 1.626 ± 0.043
2.053TyrSer: 2.053 ± 0.046
1.751TyrThr: 1.751 ± 0.04
2.05TyrVal: 2.05 ± 0.049
0.406TyrTrp: 0.406 ± 0.022
1.236TyrTyr: 1.236 ± 0.033
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3938 proteins (1042058 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski