Amino acid dipepetide frequency for Psychroserpens burtonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.735AlaAla: 3.735 ± 0.084	0.543AlaCys: 0.543 ± 0.031	3.35AlaAsp: 3.35 ± 0.065	3.485AlaGlu: 3.485 ± 0.058	3.266AlaPhe: 3.266 ± 0.059	3.874AlaGly: 3.874 ± 0.077	1.118AlaHis: 1.118 ± 0.041	5.66AlaIle: 5.66 ± 0.101	4.314AlaLys: 4.314 ± 0.083	6.208AlaLeu: 6.208 ± 0.071	1.495AlaMet: 1.495 ± 0.042	3.483AlaAsn: 3.483 ± 0.066	1.78AlaPro: 1.78 ± 0.049	2.397AlaGln: 2.397 ± 0.052	1.796AlaArg: 1.796 ± 0.044	4.178AlaSer: 4.178 ± 0.068	3.731AlaThr: 3.731 ± 0.086	3.814AlaVal: 3.814 ± 0.066	0.543AlaTrp: 0.543 ± 0.024	2.424AlaTyr: 2.424 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.464CysAla: 0.464 ± 0.023	0.087CysCys: 0.087 ± 0.008	0.555CysAsp: 0.555 ± 0.034	0.516CysGlu: 0.516 ± 0.035	0.454CysPhe: 0.454 ± 0.019	0.655CysGly: 0.655 ± 0.038	0.16CysHis: 0.16 ± 0.014	0.612CysIle: 0.612 ± 0.03	0.473CysLys: 0.473 ± 0.021	0.644CysLeu: 0.644 ± 0.027	0.138CysMet: 0.138 ± 0.011	0.424CysAsn: 0.424 ± 0.019	0.308CysPro: 0.308 ± 0.022	0.214CysGln: 0.214 ± 0.015	0.187CysArg: 0.187 ± 0.013	0.599CysSer: 0.599 ± 0.032	0.425CysThr: 0.425 ± 0.026	0.44CysVal: 0.44 ± 0.019	0.069CysTrp: 0.069 ± 0.011	0.306CysTyr: 0.306 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.962AspAla: 3.962 ± 0.07	0.523AspCys: 0.523 ± 0.032	3.801AspAsp: 3.801 ± 0.069	3.641AspGlu: 3.641 ± 0.071	3.752AspPhe: 3.752 ± 0.068	3.963AspGly: 3.963 ± 0.081	0.951AspHis: 0.951 ± 0.027	5.213AspIle: 5.213 ± 0.079	4.037AspLys: 4.037 ± 0.081	5.674AspLeu: 5.674 ± 0.085	1.231AspMet: 1.231 ± 0.033	3.711AspAsn: 3.711 ± 0.069	1.671AspPro: 1.671 ± 0.044	1.504AspGln: 1.504 ± 0.038	1.797AspArg: 1.797 ± 0.04	3.531AspSer: 3.531 ± 0.055	3.215AspThr: 3.215 ± 0.059	3.985AspVal: 3.985 ± 0.068	0.728AspTrp: 0.728 ± 0.028	2.956AspTyr: 2.956 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	4.224GluAla: 4.224 ± 0.082	0.365GluCys: 0.365 ± 0.027	3.964GluAsp: 3.964 ± 0.055	4.14GluGlu: 4.14 ± 0.083	3.047GluPhe: 3.047 ± 0.063	3.518GluGly: 3.518 ± 0.057	1.217GluHis: 1.217 ± 0.037	5.275GluIle: 5.275 ± 0.079	4.98GluLys: 4.98 ± 0.077	6.018GluLeu: 6.018 ± 0.083	1.43GluMet: 1.43 ± 0.039	4.378GluAsn: 4.378 ± 0.063	1.518GluPro: 1.518 ± 0.044	2.334GluGln: 2.334 ± 0.051	2.44GluArg: 2.44 ± 0.05	3.471GluSer: 3.471 ± 0.053	3.972GluThr: 3.972 ± 0.08	4.044GluVal: 4.044 ± 0.07	0.575GluTrp: 0.575 ± 0.027	2.233GluTyr: 2.233 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	2.804PheAla: 2.804 ± 0.048	0.422PheCys: 0.422 ± 0.017	3.551PheAsp: 3.551 ± 0.057	3.525PheGlu: 3.525 ± 0.054	2.655PhePhe: 2.655 ± 0.054	3.735PheGly: 3.735 ± 0.066	0.769PheHis: 0.769 ± 0.03	4.172PheIle: 4.172 ± 0.07	3.998PheLys: 3.998 ± 0.076	4.535PheLeu: 4.535 ± 0.066	1.088PheMet: 1.088 ± 0.031	3.551PheAsn: 3.551 ± 0.073	1.605PhePro: 1.605 ± 0.04	1.557PheGln: 1.557 ± 0.033	1.552PheArg: 1.552 ± 0.039	4.221PheSer: 4.221 ± 0.063	3.289PheThr: 3.289 ± 0.064	3.006PheVal: 3.006 ± 0.05	0.513PheTrp: 0.513 ± 0.02	2.153PheTyr: 2.153 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	4.005GlyAla: 4.005 ± 0.073	0.627GlyCys: 0.627 ± 0.04	3.694GlyAsp: 3.694 ± 0.058	3.518GlyGlu: 3.518 ± 0.065	3.739GlyPhe: 3.739 ± 0.064	4.318GlyGly: 4.318 ± 0.092	1.109GlyHis: 1.109 ± 0.036	5.211GlyIle: 5.211 ± 0.072	4.342GlyLys: 4.342 ± 0.076	5.709GlyLeu: 5.709 ± 0.083	1.453GlyMet: 1.453 ± 0.043	3.726GlyAsn: 3.726 ± 0.071	1.309GlyPro: 1.309 ± 0.036	1.928GlyGln: 1.928 ± 0.053	1.971GlyArg: 1.971 ± 0.043	4.031GlySer: 4.031 ± 0.089	4.181GlyThr: 4.181 ± 0.111	4.145GlyVal: 4.145 ± 0.063	0.658GlyTrp: 0.658 ± 0.022	2.661GlyTyr: 2.661 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	0.927HisAla: 0.927 ± 0.029	0.186HisCys: 0.186 ± 0.013	0.867HisAsp: 0.867 ± 0.032	0.927HisGlu: 0.927 ± 0.029	1.077HisPhe: 1.077 ± 0.036	1.005HisGly: 1.005 ± 0.032	0.49HisHis: 0.49 ± 0.025	1.546HisIle: 1.546 ± 0.041	1.287HisLys: 1.287 ± 0.038	1.804HisLeu: 1.804 ± 0.048	0.306HisMet: 0.306 ± 0.018	1.029HisAsn: 1.029 ± 0.031	0.786HisPro: 0.786 ± 0.027	0.681HisGln: 0.681 ± 0.023	0.615HisArg: 0.615 ± 0.024	1.027HisSer: 1.027 ± 0.03	0.944HisThr: 0.944 ± 0.031	0.965HisVal: 0.965 ± 0.029	0.201HisTrp: 0.201 ± 0.014	0.851HisTyr: 0.851 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.515IleAla: 5.515 ± 0.082	0.639IleCys: 0.639 ± 0.028	5.457IleAsp: 5.457 ± 0.074	5.933IleGlu: 5.933 ± 0.086	3.667IlePhe: 3.667 ± 0.06	5.332IleGly: 5.332 ± 0.077	1.326IleHis: 1.326 ± 0.035	6.745IleIle: 6.745 ± 0.088	6.255IleLys: 6.255 ± 0.086	7.266IleLeu: 7.266 ± 0.098	1.431IleMet: 1.431 ± 0.04	5.163IleAsn: 5.163 ± 0.08	3.141IlePro: 3.141 ± 0.051	2.52IleGln: 2.52 ± 0.048	2.483IleArg: 2.483 ± 0.044	6.068IleSer: 6.068 ± 0.084	5.481IleThr: 5.481 ± 0.108	4.926IleVal: 4.926 ± 0.068	0.69IleTrp: 0.69 ± 0.028	2.848IleTyr: 2.848 ± 0.052	0.0IleXaa: 0.0 ± 0.0
Lys	4.841LysAla: 4.841 ± 0.084	0.351LysCys: 0.351 ± 0.017	4.561LysAsp: 4.561 ± 0.089	5.444LysGlu: 5.444 ± 0.096	2.966LysPhe: 2.966 ± 0.06	4.328LysGly: 4.328 ± 0.076	1.479LysHis: 1.479 ± 0.037	5.907LysIle: 5.907 ± 0.084	6.21LysLys: 6.21 ± 0.108	6.625LysLeu: 6.625 ± 0.089	1.861LysMet: 1.861 ± 0.04	4.857LysAsn: 4.857 ± 0.084	2.222LysPro: 2.222 ± 0.047	2.84LysGln: 2.84 ± 0.054	3.103LysArg: 3.103 ± 0.052	4.783LysSer: 4.783 ± 0.076	5.077LysThr: 5.077 ± 0.074	4.35LysVal: 4.35 ± 0.071	0.714LysTrp: 0.714 ± 0.023	2.781LysTyr: 2.781 ± 0.057	0.0LysXaa: 0.0 ± 0.0
Leu	5.42LeuAla: 5.42 ± 0.08	0.702LeuCys: 0.702 ± 0.023	5.433LeuAsp: 5.433 ± 0.084	6.239LeuGlu: 6.239 ± 0.095	4.9LeuPhe: 4.9 ± 0.075	5.516LeuGly: 5.516 ± 0.084	1.49LeuHis: 1.49 ± 0.042	7.342LeuIle: 7.342 ± 0.102	7.98LeuLys: 7.98 ± 0.112	8.468LeuLeu: 8.468 ± 0.119	1.981LeuMet: 1.981 ± 0.048	6.034LeuAsn: 6.034 ± 0.08	3.268LeuPro: 3.268 ± 0.06	3.066LeuGln: 3.066 ± 0.051	3.13LeuArg: 3.13 ± 0.057	6.701LeuSer: 6.701 ± 0.077	5.185LeuThr: 5.185 ± 0.078	5.618LeuVal: 5.618 ± 0.071	0.82LeuTrp: 0.82 ± 0.036	3.197LeuTyr: 3.197 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.458MetAla: 1.458 ± 0.037	0.131MetCys: 0.131 ± 0.012	1.124MetAsp: 1.124 ± 0.032	1.187MetGlu: 1.187 ± 0.033	0.893MetPhe: 0.893 ± 0.028	1.139MetGly: 1.139 ± 0.037	0.396MetHis: 0.396 ± 0.023	1.674MetIle: 1.674 ± 0.037	2.076MetLys: 2.076 ± 0.039	1.923MetLeu: 1.923 ± 0.041	0.554MetMet: 0.554 ± 0.028	1.295MetAsn: 1.295 ± 0.031	0.772MetPro: 0.772 ± 0.028	0.793MetGln: 0.793 ± 0.031	0.844MetArg: 0.844 ± 0.027	1.611MetSer: 1.611 ± 0.044	1.306MetThr: 1.306 ± 0.034	1.26MetVal: 1.26 ± 0.034	0.13MetTrp: 0.13 ± 0.01	0.743MetTyr: 0.743 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	3.953AsnAla: 3.953 ± 0.06	0.53AsnCys: 0.53 ± 0.028	3.783AsnAsp: 3.783 ± 0.07	3.818AsnGlu: 3.818 ± 0.07	3.117AsnPhe: 3.117 ± 0.058	4.101AsnGly: 4.101 ± 0.081	1.045AsnHis: 1.045 ± 0.027	5.016AsnIle: 5.016 ± 0.078	4.325AsnLys: 4.325 ± 0.072	5.501AsnLeu: 5.501 ± 0.074	1.334AsnMet: 1.334 ± 0.034	4.105AsnAsn: 4.105 ± 0.071	2.718AsnPro: 2.718 ± 0.052	2.35AsnGln: 2.35 ± 0.051	2.155AsnArg: 2.155 ± 0.046	4.318AsnSer: 4.318 ± 0.079	4.299AsnThr: 4.299 ± 0.082	3.674AsnVal: 3.674 ± 0.067	0.769AsnTrp: 0.769 ± 0.027	3.029AsnTyr: 3.029 ± 0.058	0.0AsnXaa: 0.0 ± 0.0
Pro	1.633ProAla: 1.633 ± 0.045	0.213ProCys: 0.213 ± 0.016	1.891ProAsp: 1.891 ± 0.041	2.498ProGlu: 2.498 ± 0.052	1.807ProPhe: 1.807 ± 0.038	1.688ProGly: 1.688 ± 0.044	0.529ProHis: 0.529 ± 0.021	2.737ProIle: 2.737 ± 0.05	2.476ProLys: 2.476 ± 0.06	2.77ProLeu: 2.77 ± 0.055	0.661ProMet: 0.661 ± 0.024	2.406ProAsn: 2.406 ± 0.063	0.726ProPro: 0.726 ± 0.03	1.083ProGln: 1.083 ± 0.032	0.877ProArg: 0.877 ± 0.031	2.165ProSer: 2.165 ± 0.043	2.039ProThr: 2.039 ± 0.049	1.953ProVal: 1.953 ± 0.047	0.299ProTrp: 0.299 ± 0.018	1.273ProTyr: 1.273 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	1.941GlnAla: 1.941 ± 0.048	0.191GlnCys: 0.191 ± 0.014	1.925GlnAsp: 1.925 ± 0.044	2.115GlnGlu: 2.115 ± 0.04	1.826GlnPhe: 1.826 ± 0.041	1.8GlnGly: 1.8 ± 0.038	0.61GlnHis: 0.61 ± 0.022	2.79GlnIle: 2.79 ± 0.051	2.541GlnLys: 2.541 ± 0.059	3.591GlnLeu: 3.591 ± 0.061	0.819GlnMet: 0.819 ± 0.029	2.287GlnAsn: 2.287 ± 0.056	1.09GlnPro: 1.09 ± 0.032	1.348GlnGln: 1.348 ± 0.038	1.221GlnArg: 1.221 ± 0.034	2.031GlnSer: 2.031 ± 0.038	2.051GlnThr: 2.051 ± 0.049	1.956GlnVal: 1.956 ± 0.04	0.332GlnTrp: 0.332 ± 0.019	1.281GlnTyr: 1.281 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.022ArgAla: 2.022 ± 0.047	0.179ArgCys: 0.179 ± 0.012	1.918ArgAsp: 1.918 ± 0.044	1.945ArgGlu: 1.945 ± 0.048	1.884ArgPhe: 1.884 ± 0.044	1.846ArgGly: 1.846 ± 0.047	0.631ArgHis: 0.631 ± 0.022	2.767ArgIle: 2.767 ± 0.049	2.561ArgLys: 2.561 ± 0.052	3.276ArgLeu: 3.276 ± 0.062	0.785ArgMet: 0.785 ± 0.027	1.993ArgAsn: 1.993 ± 0.045	0.993ArgPro: 0.993 ± 0.03	1.208ArgGln: 1.208 ± 0.031	1.271ArgArg: 1.271 ± 0.038	1.912ArgSer: 1.912 ± 0.043	1.899ArgThr: 1.899 ± 0.04	2.135ArgVal: 2.135 ± 0.049	0.327ArgTrp: 0.327 ± 0.019	1.463ArgTyr: 1.463 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	3.865SerAla: 3.865 ± 0.068	0.725SerCys: 0.725 ± 0.04	3.672SerAsp: 3.672 ± 0.058	4.253SerGlu: 4.253 ± 0.066	3.827SerPhe: 3.827 ± 0.061	4.755SerGly: 4.755 ± 0.094	1.137SerHis: 1.137 ± 0.029	5.659SerIle: 5.659 ± 0.082	5.273SerLys: 5.273 ± 0.08	6.042SerLeu: 6.042 ± 0.079	1.32SerMet: 1.32 ± 0.034	4.392SerAsn: 4.392 ± 0.071	2.057SerPro: 2.057 ± 0.045	2.431SerGln: 2.431 ± 0.046	2.112SerArg: 2.112 ± 0.045	4.725SerSer: 4.725 ± 0.08	3.788SerThr: 3.788 ± 0.069	4.042SerVal: 4.042 ± 0.066	0.723SerTrp: 0.723 ± 0.028	2.803SerTyr: 2.803 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	3.747ThrAla: 3.747 ± 0.074	0.39ThrCys: 0.39 ± 0.028	3.561ThrAsp: 3.561 ± 0.074	3.44ThrGlu: 3.44 ± 0.055	3.388ThrPhe: 3.388 ± 0.061	4.103ThrGly: 4.103 ± 0.095	1.097ThrHis: 1.097 ± 0.034	5.668ThrIle: 5.668 ± 0.109	4.091ThrLys: 4.091 ± 0.068	5.728ThrLeu: 5.728 ± 0.077	1.05ThrMet: 1.05 ± 0.03	3.968ThrAsn: 3.968 ± 0.075	2.261ThrPro: 2.261 ± 0.053	2.025ThrGln: 2.025 ± 0.042	1.683ThrArg: 1.683 ± 0.039	4.344ThrSer: 4.344 ± 0.08	4.072ThrThr: 4.072 ± 0.114	4.17ThrVal: 4.17 ± 0.082	0.608ThrTrp: 0.608 ± 0.033	2.658ThrTyr: 2.658 ± 0.065	0.0ThrXaa: 0.0 ± 0.0
Val	3.794ValAla: 3.794 ± 0.064	0.506ValCys: 0.506 ± 0.024	3.684ValAsp: 3.684 ± 0.057	3.701ValGlu: 3.701 ± 0.06	3.487ValPhe: 3.487 ± 0.069	3.69ValGly: 3.69 ± 0.065	0.958ValHis: 0.958 ± 0.034	5.237ValIle: 5.237 ± 0.073	4.252ValLys: 4.252 ± 0.071	6.079ValLeu: 6.079 ± 0.08	1.341ValMet: 1.341 ± 0.033	3.676ValAsn: 3.676 ± 0.059	1.954ValPro: 1.954 ± 0.043	1.64ValGln: 1.64 ± 0.038	1.907ValArg: 1.907 ± 0.051	4.532ValSer: 4.532 ± 0.063	3.938ValThr: 3.938 ± 0.087	4.086ValVal: 4.086 ± 0.075	0.59ValTrp: 0.59 ± 0.02	2.327ValTyr: 2.327 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.509TrpAla: 0.509 ± 0.021	0.079TrpCys: 0.079 ± 0.007	0.583TrpAsp: 0.583 ± 0.026	0.603TrpGlu: 0.603 ± 0.022	0.576TrpPhe: 0.576 ± 0.026	0.523TrpGly: 0.523 ± 0.023	0.219TrpHis: 0.219 ± 0.014	0.776TrpIle: 0.776 ± 0.033	0.717TrpLys: 0.717 ± 0.028	0.951TrpLeu: 0.951 ± 0.032	0.286TrpMet: 0.286 ± 0.016	0.675TrpAsn: 0.675 ± 0.026	0.186TrpPro: 0.186 ± 0.014	0.38TrpGln: 0.38 ± 0.021	0.369TrpArg: 0.369 ± 0.018	0.715TrpSer: 0.715 ± 0.027	0.617TrpThr: 0.617 ± 0.028	0.586TrpVal: 0.586 ± 0.025	0.138TrpTrp: 0.138 ± 0.014	0.408TrpTyr: 0.408 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.374TyrAla: 2.374 ± 0.046	0.342TyrCys: 0.342 ± 0.018	2.47TyrAsp: 2.47 ± 0.058	2.216TyrGlu: 2.216 ± 0.052	2.371TyrPhe: 2.371 ± 0.049	2.444TyrGly: 2.444 ± 0.048	0.793TyrHis: 0.793 ± 0.028	2.879TyrIle: 2.879 ± 0.051	3.115TyrLys: 3.115 ± 0.067	3.68TyrLeu: 3.68 ± 0.058	0.745TyrMet: 0.745 ± 0.023	2.786TyrAsn: 2.786 ± 0.053	1.358TyrPro: 1.358 ± 0.035	1.447TyrGln: 1.447 ± 0.039	1.502TyrArg: 1.502 ± 0.036	2.637TyrSer: 2.637 ± 0.048	2.544TyrThr: 2.544 ± 0.062	2.226TyrVal: 2.226 ± 0.051	0.468TyrTrp: 0.468 ± 0.024	1.787TyrTyr: 1.787 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3458 proteins (1151945 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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