Amino acid dipepetide frequency for Arcobacter nitrofigilis (strain ATCC 33309 / DSM 7299 / LMG 7604 / NCTC 12251 / CI) (Campylobacter nitrofigilis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.506AlaAla: 3.506 ± 0.092
0.648AlaCys: 0.648 ± 0.024
2.497AlaAsp: 2.497 ± 0.065
2.382AlaGlu: 2.382 ± 0.063
2.867AlaPhe: 2.867 ± 0.069
3.619AlaGly: 3.619 ± 0.082
1.038AlaHis: 1.038 ± 0.033
5.854AlaIle: 5.854 ± 0.09
5.584AlaLys: 5.584 ± 0.083
6.294AlaLeu: 6.294 ± 0.088
1.712AlaMet: 1.712 ± 0.051
3.42AlaAsn: 3.42 ± 0.065
1.483AlaPro: 1.483 ± 0.047
1.866AlaGln: 1.866 ± 0.043
1.707AlaArg: 1.707 ± 0.044
3.951AlaSer: 3.951 ± 0.082
3.259AlaThr: 3.259 ± 0.063
3.582AlaVal: 3.582 ± 0.067
0.444AlaTrp: 0.444 ± 0.025
2.232AlaTyr: 2.232 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
0.55CysAla: 0.55 ± 0.027
0.11CysCys: 0.11 ± 0.012
0.644CysAsp: 0.644 ± 0.026
0.698CysGlu: 0.698 ± 0.028
0.364CysPhe: 0.364 ± 0.019
0.741CysGly: 0.741 ± 0.028
0.217CysHis: 0.217 ± 0.017
0.736CysIle: 0.736 ± 0.028
0.767CysLys: 0.767 ± 0.03
0.698CysLeu: 0.698 ± 0.027
0.2CysMet: 0.2 ± 0.015
0.473CysAsn: 0.473 ± 0.025
0.37CysPro: 0.37 ± 0.023
0.212CysGln: 0.212 ± 0.016
0.23CysArg: 0.23 ± 0.016
0.654CysSer: 0.654 ± 0.027
0.451CysThr: 0.451 ± 0.021
0.52CysVal: 0.52 ± 0.027
0.056CysTrp: 0.056 ± 0.007
0.29CysTyr: 0.29 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
3.107AspAla: 3.107 ± 0.071
0.47AspCys: 0.47 ± 0.024
3.179AspAsp: 3.179 ± 0.094
4.918AspGlu: 4.918 ± 0.072
3.412AspPhe: 3.412 ± 0.062
3.494AspGly: 3.494 ± 0.18
0.567AspHis: 0.567 ± 0.023
6.259AspIle: 6.259 ± 0.089
5.497AspLys: 5.497 ± 0.084
5.271AspLeu: 5.271 ± 0.076
1.356AspMet: 1.356 ± 0.041
3.229AspAsn: 3.229 ± 0.063
1.212AspPro: 1.212 ± 0.036
0.816AspGln: 0.816 ± 0.03
1.422AspArg: 1.422 ± 0.036
3.438AspSer: 3.438 ± 0.072
2.916AspThr: 2.916 ± 0.072
3.285AspVal: 3.285 ± 0.072
0.406AspTrp: 0.406 ± 0.022
2.581AspTyr: 2.581 ± 0.052
0.0AspXaa: 0.0 ± 0.0
Glu
4.056GluAla: 4.056 ± 0.081
0.514GluCys: 0.514 ± 0.025
3.986GluAsp: 3.986 ± 0.083
5.687GluGlu: 5.687 ± 0.101
3.393GluPhe: 3.393 ± 0.064
3.019GluGly: 3.019 ± 0.077
1.188GluHis: 1.188 ± 0.04
6.636GluIle: 6.636 ± 0.089
7.428GluLys: 7.428 ± 0.102
7.084GluLeu: 7.084 ± 0.092
1.554GluMet: 1.554 ± 0.048
5.246GluAsn: 5.246 ± 0.078
1.369GluPro: 1.369 ± 0.037
2.056GluGln: 2.056 ± 0.055
1.705GluArg: 1.705 ± 0.051
3.633GluSer: 3.633 ± 0.068
3.046GluThr: 3.046 ± 0.071
4.417GluVal: 4.417 ± 0.061
0.401GluTrp: 0.401 ± 0.019
2.94GluTyr: 2.94 ± 0.055
0.0GluXaa: 0.0 ± 0.0
Phe
3.039PheAla: 3.039 ± 0.07
0.551PheCys: 0.551 ± 0.024
3.464PheAsp: 3.464 ± 0.072
3.59PheGlu: 3.59 ± 0.07
2.878PhePhe: 2.878 ± 0.064
3.139PheGly: 3.139 ± 0.066
0.736PheHis: 0.736 ± 0.027
5.059PheIle: 5.059 ± 0.082
4.155PheLys: 4.155 ± 0.07
5.022PheLeu: 5.022 ± 0.089
1.219PheMet: 1.219 ± 0.035
2.893PheAsn: 2.893 ± 0.057
1.285PhePro: 1.285 ± 0.038
1.127PheGln: 1.127 ± 0.032
1.301PheArg: 1.301 ± 0.038
3.737PheSer: 3.737 ± 0.069
2.818PheThr: 2.818 ± 0.055
2.987PheVal: 2.987 ± 0.067
0.454PheTrp: 0.454 ± 0.025
2.127PheTyr: 2.127 ± 0.053
0.0PheXaa: 0.0 ± 0.0
Gly
3.627GlyAla: 3.627 ± 0.084
0.664GlyCys: 0.664 ± 0.029
2.793GlyAsp: 2.793 ± 0.088
3.462GlyGlu: 3.462 ± 0.095
3.248GlyPhe: 3.248 ± 0.071
3.805GlyGly: 3.805 ± 0.103
0.982GlyHis: 0.982 ± 0.032
5.421GlyIle: 5.421 ± 0.091
4.736GlyLys: 4.736 ± 0.077
5.263GlyLeu: 5.263 ± 0.081
1.515GlyMet: 1.515 ± 0.045
2.641GlyAsn: 2.641 ± 0.104
0.983GlyPro: 0.983 ± 0.038
1.367GlyGln: 1.367 ± 0.035
1.606GlyArg: 1.606 ± 0.045
3.512GlySer: 3.512 ± 0.082
3.224GlyThr: 3.224 ± 0.119
3.933GlyVal: 3.933 ± 0.068
0.504GlyTrp: 0.504 ± 0.024
2.511GlyTyr: 2.511 ± 0.052
0.0GlyXaa: 0.0 ± 0.0
His
0.837HisAla: 0.837 ± 0.03
0.157HisCys: 0.157 ± 0.013
0.803HisAsp: 0.803 ± 0.035
1.016HisGlu: 1.016 ± 0.032
0.873HisPhe: 0.873 ± 0.028
0.997HisGly: 0.997 ± 0.03
0.339HisHis: 0.339 ± 0.024
1.433HisIle: 1.433 ± 0.035
1.285HisLys: 1.285 ± 0.041
1.513HisLeu: 1.513 ± 0.038
0.369HisMet: 0.369 ± 0.02
0.904HisAsn: 0.904 ± 0.033
0.67HisPro: 0.67 ± 0.027
0.497HisGln: 0.497 ± 0.024
0.505HisArg: 0.505 ± 0.023
0.98HisSer: 0.98 ± 0.034
0.912HisThr: 0.912 ± 0.033
0.692HisVal: 0.692 ± 0.031
0.159HisTrp: 0.159 ± 0.014
0.638HisTyr: 0.638 ± 0.024
0.0HisXaa: 0.0 ± 0.0
Ile
5.922IleAla: 5.922 ± 0.091
0.864IleCys: 0.864 ± 0.035
6.032IleAsp: 6.032 ± 0.116
6.789IleGlu: 6.789 ± 0.09
4.911IlePhe: 4.911 ± 0.089
5.369IleGly: 5.369 ± 0.077
1.339IleHis: 1.339 ± 0.037
8.693IleIle: 8.693 ± 0.141
9.064IleLys: 9.064 ± 0.12
9.267IleLeu: 9.267 ± 0.124
1.833IleMet: 1.833 ± 0.042
6.245IleAsn: 6.245 ± 0.103
2.983IlePro: 2.983 ± 0.053
2.323IleGln: 2.323 ± 0.049
2.333IleArg: 2.333 ± 0.049
7.23IleSer: 7.23 ± 0.093
5.18IleThr: 5.18 ± 0.134
5.525IleVal: 5.525 ± 0.083
0.54IleTrp: 0.54 ± 0.023
3.537IleTyr: 3.537 ± 0.068
0.0IleXaa: 0.0 ± 0.0
Lys
5.135LysAla: 5.135 ± 0.084
0.544LysCys: 0.544 ± 0.024
6.61LysAsp: 6.61 ± 0.096
9.005LysGlu: 9.005 ± 0.112
3.591LysPhe: 3.591 ± 0.073
3.971LysGly: 3.971 ± 0.069
1.273LysHis: 1.273 ± 0.037
8.801LysIle: 8.801 ± 0.118
9.442LysLys: 9.442 ± 0.135
8.182LysLeu: 8.182 ± 0.101
2.266LysMet: 2.266 ± 0.049
7.282LysAsn: 7.282 ± 0.109
2.357LysPro: 2.357 ± 0.049
2.597LysGln: 2.597 ± 0.054
3.094LysArg: 3.094 ± 0.064
5.625LysSer: 5.625 ± 0.092
4.636LysThr: 4.636 ± 0.081
5.459LysVal: 5.459 ± 0.09
0.58LysTrp: 0.58 ± 0.028
4.141LysTyr: 4.141 ± 0.066
0.0LysXaa: 0.0 ± 0.0
Leu
5.696LeuAla: 5.696 ± 0.082
0.935LeuCys: 0.935 ± 0.036
5.614LeuAsp: 5.614 ± 0.083
7.085LeuGlu: 7.085 ± 0.11
5.214LeuPhe: 5.214 ± 0.096
5.435LeuGly: 5.435 ± 0.084
1.358LeuHis: 1.358 ± 0.041
8.359LeuIle: 8.359 ± 0.115
9.268LeuLys: 9.268 ± 0.113
9.266LeuLeu: 9.266 ± 0.136
2.097LeuMet: 2.097 ± 0.053
6.521LeuAsn: 6.521 ± 0.095
3.136LeuPro: 3.136 ± 0.067
2.602LeuGln: 2.602 ± 0.053
2.725LeuArg: 2.725 ± 0.059
7.365LeuSer: 7.365 ± 0.091
4.91LeuThr: 4.91 ± 0.071
5.369LeuVal: 5.369 ± 0.075
0.638LeuTrp: 0.638 ± 0.027
3.532LeuTyr: 3.532 ± 0.07
0.0LeuXaa: 0.0 ± 0.0
Met
1.564MetAla: 1.564 ± 0.045
0.175MetCys: 0.175 ± 0.014
1.207MetAsp: 1.207 ± 0.034
1.272MetGlu: 1.272 ± 0.039
1.14MetPhe: 1.14 ± 0.04
1.47MetGly: 1.47 ± 0.04
0.402MetHis: 0.402 ± 0.022
2.139MetIle: 2.139 ± 0.051
2.274MetLys: 2.274 ± 0.052
2.138MetLeu: 2.138 ± 0.054
0.599MetMet: 0.599 ± 0.027
1.51MetAsn: 1.51 ± 0.038
0.89MetPro: 0.89 ± 0.03
0.782MetGln: 0.782 ± 0.032
0.71MetArg: 0.71 ± 0.026
1.732MetSer: 1.732 ± 0.044
1.114MetThr: 1.114 ± 0.037
1.322MetVal: 1.322 ± 0.038
0.166MetTrp: 0.166 ± 0.014
0.678MetTyr: 0.678 ± 0.027
0.0MetXaa: 0.0 ± 0.0
Asn
3.139AsnAla: 3.139 ± 0.066
0.527AsnCys: 0.527 ± 0.028
3.449AsnAsp: 3.449 ± 0.073
4.656AsnGlu: 4.656 ± 0.078
3.035AsnPhe: 3.035 ± 0.061
3.193AsnGly: 3.193 ± 0.088
0.994AsnHis: 0.994 ± 0.034
7.031AsnIle: 7.031 ± 0.104
6.318AsnLys: 6.318 ± 0.097
6.263AsnLeu: 6.263 ± 0.081
1.345AsnMet: 1.345 ± 0.041
4.128AsnAsn: 4.128 ± 0.08
2.114AsnPro: 2.114 ± 0.049
1.746AsnGln: 1.746 ± 0.044
1.867AsnArg: 1.867 ± 0.047
4.548AsnSer: 4.548 ± 0.079
3.227AsnThr: 3.227 ± 0.062
3.212AsnVal: 3.212 ± 0.065
0.459AsnTrp: 0.459 ± 0.023
2.636AsnTyr: 2.636 ± 0.06
0.0AsnXaa: 0.0 ± 0.0
Pro
1.387ProAla: 1.387 ± 0.04
0.242ProCys: 0.242 ± 0.017
1.389ProAsp: 1.389 ± 0.04
1.735ProGlu: 1.735 ± 0.047
1.588ProPhe: 1.588 ± 0.044
1.27ProGly: 1.27 ± 0.045
0.521ProHis: 0.521 ± 0.024
2.735ProIle: 2.735 ± 0.054
2.675ProLys: 2.675 ± 0.055
2.765ProLeu: 2.765 ± 0.063
0.67ProMet: 0.67 ± 0.03
1.759ProAsn: 1.759 ± 0.043
0.663ProPro: 0.663 ± 0.03
0.872ProGln: 0.872 ± 0.036
0.736ProArg: 0.736 ± 0.026
1.848ProSer: 1.848 ± 0.041
1.651ProThr: 1.651 ± 0.046
1.631ProVal: 1.631 ± 0.044
0.244ProTrp: 0.244 ± 0.016
1.317ProTyr: 1.317 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
1.598GlnAla: 1.598 ± 0.046
0.171GlnCys: 0.171 ± 0.014
1.416GlnAsp: 1.416 ± 0.037
1.966GlnGlu: 1.966 ± 0.049
1.099GlnPhe: 1.099 ± 0.036
1.316GlnGly: 1.316 ± 0.036
0.344GlnHis: 0.344 ± 0.02
2.635GlnIle: 2.635 ± 0.064
2.924GlnLys: 2.924 ± 0.06
2.266GlnLeu: 2.266 ± 0.056
0.697GlnMet: 0.697 ± 0.027
2.088GlnAsn: 2.088 ± 0.052
0.563GlnPro: 0.563 ± 0.021
0.695GlnGln: 0.695 ± 0.027
1.047GlnArg: 1.047 ± 0.032
1.638GlnSer: 1.638 ± 0.042
1.571GlnThr: 1.571 ± 0.041
1.535GlnVal: 1.535 ± 0.066
0.283GlnTrp: 0.283 ± 0.017
0.966GlnTyr: 0.966 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
1.759ArgAla: 1.759 ± 0.041
0.242ArgCys: 0.242 ± 0.016
1.68ArgAsp: 1.68 ± 0.051
2.002ArgGlu: 2.002 ± 0.048
1.535ArgPhe: 1.535 ± 0.043
1.578ArgGly: 1.578 ± 0.045
0.489ArgHis: 0.489 ± 0.028
2.468ArgIle: 2.468 ± 0.056
2.315ArgLys: 2.315 ± 0.048
2.685ArgLeu: 2.685 ± 0.052
0.681ArgMet: 0.681 ± 0.028
1.592ArgAsn: 1.592 ± 0.041
0.775ArgPro: 0.775 ± 0.03
0.721ArgGln: 0.721 ± 0.027
1.066ArgArg: 1.066 ± 0.038
1.354ArgSer: 1.354 ± 0.036
1.388ArgThr: 1.388 ± 0.044
2.202ArgVal: 2.202 ± 0.048
0.212ArgTrp: 0.212 ± 0.015
1.251ArgTyr: 1.251 ± 0.041
0.0ArgXaa: 0.0 ± 0.0
Ser
3.615SerAla: 3.615 ± 0.063
0.609SerCys: 0.609 ± 0.027
3.396SerAsp: 3.396 ± 0.079
3.475SerGlu: 3.475 ± 0.066
4.014SerPhe: 4.014 ± 0.065
3.93SerGly: 3.93 ± 0.072
1.142SerHis: 1.142 ± 0.038
6.798SerIle: 6.798 ± 0.111
6.467SerLys: 6.467 ± 0.086
6.98SerLeu: 6.98 ± 0.08
1.598SerMet: 1.598 ± 0.047
4.267SerAsn: 4.267 ± 0.078
1.611SerPro: 1.611 ± 0.044
1.971SerGln: 1.971 ± 0.048
1.789SerArg: 1.789 ± 0.048
5.168SerSer: 5.168 ± 0.096
3.629SerThr: 3.629 ± 0.065
3.509SerVal: 3.509 ± 0.058
0.598SerTrp: 0.598 ± 0.025
2.891SerTyr: 2.891 ± 0.054
0.0SerXaa: 0.0 ± 0.0
Thr
3.084ThrAla: 3.084 ± 0.075
0.418ThrCys: 0.418 ± 0.023
2.356ThrAsp: 2.356 ± 0.088
2.226ThrGlu: 2.226 ± 0.05
2.722ThrPhe: 2.722 ± 0.059
3.136ThrGly: 3.136 ± 0.11
0.915ThrHis: 0.915 ± 0.035
5.342ThrIle: 5.342 ± 0.092
4.869ThrLys: 4.869 ± 0.083
5.449ThrLeu: 5.449 ± 0.087
1.084ThrMet: 1.084 ± 0.033
3.404ThrAsn: 3.404 ± 0.072
1.987ThrPro: 1.987 ± 0.045
1.694ThrGln: 1.694 ± 0.047
1.296ThrArg: 1.296 ± 0.035
3.736ThrSer: 3.736 ± 0.099
3.272ThrThr: 3.272 ± 0.091
3.003ThrVal: 3.003 ± 0.075
0.428ThrTrp: 0.428 ± 0.033
2.157ThrTyr: 2.157 ± 0.052
0.0ThrXaa: 0.0 ± 0.0
Val
3.736ValAla: 3.736 ± 0.064
0.663ValCys: 0.663 ± 0.028
3.403ValAsp: 3.403 ± 0.059
3.97ValGlu: 3.97 ± 0.062
2.859ValPhe: 2.859 ± 0.062
3.62ValGly: 3.62 ± 0.073
0.917ValHis: 0.917 ± 0.036
5.325ValIle: 5.325 ± 0.075
4.931ValLys: 4.931 ± 0.073
5.825ValLeu: 5.825 ± 0.088
1.374ValMet: 1.374 ± 0.044
3.433ValAsn: 3.433 ± 0.071
1.807ValPro: 1.807 ± 0.053
1.564ValGln: 1.564 ± 0.06
1.575ValArg: 1.575 ± 0.042
4.094ValSer: 4.094 ± 0.061
3.052ValThr: 3.052 ± 0.093
3.945ValVal: 3.945 ± 0.09
0.434ValTrp: 0.434 ± 0.02
2.082ValTyr: 2.082 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
0.425TrpAla: 0.425 ± 0.021
0.068TrpCys: 0.068 ± 0.008
0.419TrpAsp: 0.419 ± 0.023
0.455TrpGlu: 0.455 ± 0.021
0.394TrpPhe: 0.394 ± 0.02
0.512TrpGly: 0.512 ± 0.024
0.181TrpHis: 0.181 ± 0.014
0.719TrpIle: 0.719 ± 0.03
0.501TrpLys: 0.501 ± 0.024
0.739TrpLeu: 0.739 ± 0.031
0.237TrpMet: 0.237 ± 0.014
0.438TrpAsn: 0.438 ± 0.021
0.167TrpPro: 0.167 ± 0.013
0.286TrpGln: 0.286 ± 0.018
0.254TrpArg: 0.254 ± 0.017
0.445TrpSer: 0.445 ± 0.023
0.339TrpThr: 0.339 ± 0.02
0.45TrpVal: 0.45 ± 0.022
0.073TrpTrp: 0.073 ± 0.01
0.304TrpTyr: 0.304 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.163TyrAla: 2.163 ± 0.053
0.405TyrCys: 0.405 ± 0.018
2.501TyrAsp: 2.501 ± 0.055
2.97TyrGlu: 2.97 ± 0.062
2.444TyrPhe: 2.444 ± 0.057
2.188TyrGly: 2.188 ± 0.05
0.637TyrHis: 0.637 ± 0.028
3.536TyrIle: 3.536 ± 0.064
4.09TyrLys: 4.09 ± 0.077
4.153TyrLeu: 4.153 ± 0.07
0.877TyrMet: 0.877 ± 0.032
2.41TyrAsn: 2.41 ± 0.055
1.271TyrPro: 1.271 ± 0.042
1.024TyrGln: 1.024 ± 0.034
1.026TyrArg: 1.026 ± 0.033
2.766TyrSer: 2.766 ± 0.068
1.987TyrThr: 1.987 ± 0.051
2.034TyrVal: 2.034 ± 0.081
0.328TyrTrp: 0.328 ± 0.019
1.69TyrTyr: 1.69 ± 0.04
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3125 proteins (987378 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski