Amino acid dipepetide frequency for Dishui Lake phycodnavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.843AlaAla: 6.843 ± 1.588
1.333AlaCys: 1.333 ± 0.236
3.373AlaAsp: 3.373 ± 0.276
3.235AlaGlu: 3.235 ± 0.388
2.392AlaPhe: 2.392 ± 0.245
4.118AlaGly: 4.118 ± 0.355
1.49AlaHis: 1.49 ± 0.175
3.373AlaIle: 3.373 ± 0.268
4.0AlaLys: 4.0 ± 0.5
5.961AlaLeu: 5.961 ± 0.388
1.804AlaMet: 1.804 ± 0.208
4.353AlaAsn: 4.353 ± 0.798
2.608AlaPro: 2.608 ± 0.325
2.647AlaGln: 2.647 ± 0.246
3.588AlaArg: 3.588 ± 0.335
4.039AlaSer: 4.039 ± 0.393
3.98AlaThr: 3.98 ± 0.384
4.177AlaVal: 4.177 ± 0.308
0.608AlaTrp: 0.608 ± 0.122
2.451AlaTyr: 2.451 ± 0.187
0.0AlaXaa: 0.0 ± 0.0
Cys
1.118CysAla: 1.118 ± 0.191
0.392CysCys: 0.392 ± 0.094
1.078CysAsp: 1.078 ± 0.172
1.0CysGlu: 1.0 ± 0.186
0.726CysPhe: 0.726 ± 0.127
1.333CysGly: 1.333 ± 0.205
0.392CysHis: 0.392 ± 0.093
0.608CysIle: 0.608 ± 0.11
1.157CysLys: 1.157 ± 0.181
1.373CysLeu: 1.373 ± 0.196
0.686CysMet: 0.686 ± 0.135
0.745CysAsn: 0.745 ± 0.137
1.118CysPro: 1.118 ± 0.207
0.569CysGln: 0.569 ± 0.119
1.059CysArg: 1.059 ± 0.182
1.118CysSer: 1.118 ± 0.164
0.98CysThr: 0.98 ± 0.168
1.196CysVal: 1.196 ± 0.159
0.176CysTrp: 0.176 ± 0.056
0.569CysTyr: 0.569 ± 0.117
0.0CysXaa: 0.0 ± 0.0
Asp
4.216AspAla: 4.216 ± 0.332
0.941AspCys: 0.941 ± 0.192
4.314AspAsp: 4.314 ± 0.388
4.235AspGlu: 4.235 ± 0.397
2.686AspPhe: 2.686 ± 0.297
4.333AspGly: 4.333 ± 0.39
0.922AspHis: 0.922 ± 0.131
3.98AspIle: 3.98 ± 0.422
2.726AspLys: 2.726 ± 0.261
4.412AspLeu: 4.412 ± 0.287
1.726AspMet: 1.726 ± 0.173
2.569AspAsn: 2.569 ± 0.315
2.373AspPro: 2.373 ± 0.229
1.176AspGln: 1.176 ± 0.156
2.608AspArg: 2.608 ± 0.228
2.157AspSer: 2.157 ± 0.291
4.431AspThr: 4.431 ± 0.359
5.177AspVal: 5.177 ± 0.286
0.765AspTrp: 0.765 ± 0.129
2.294AspTyr: 2.294 ± 0.201
0.0AspXaa: 0.0 ± 0.0
Glu
3.569GluAla: 3.569 ± 0.404
1.196GluCys: 1.196 ± 0.175
3.196GluAsp: 3.196 ± 0.29
4.726GluGlu: 4.726 ± 0.519
3.157GluPhe: 3.157 ± 0.264
3.177GluGly: 3.177 ± 0.287
1.451GluHis: 1.451 ± 0.19
3.431GluIle: 3.431 ± 0.369
4.177GluLys: 4.177 ± 0.319
5.314GluLeu: 5.314 ± 0.5
1.745GluMet: 1.745 ± 0.238
2.902GluAsn: 2.902 ± 0.292
2.549GluPro: 2.549 ± 0.302
2.588GluGln: 2.588 ± 0.309
3.784GluArg: 3.784 ± 0.329
2.392GluSer: 2.392 ± 0.191
3.549GluThr: 3.549 ± 0.282
4.902GluVal: 4.902 ± 0.352
0.706GluTrp: 0.706 ± 0.127
2.804GluTyr: 2.804 ± 0.264
0.0GluXaa: 0.0 ± 0.0
Phe
2.314PheAla: 2.314 ± 0.27
0.882PheCys: 0.882 ± 0.172
2.843PheAsp: 2.843 ± 0.32
2.275PheGlu: 2.275 ± 0.234
2.177PhePhe: 2.177 ± 0.261
2.804PheGly: 2.804 ± 0.223
0.922PheHis: 0.922 ± 0.154
3.02PheIle: 3.02 ± 0.25
2.824PheLys: 2.824 ± 0.285
3.275PheLeu: 3.275 ± 0.293
1.333PheMet: 1.333 ± 0.19
2.686PheAsn: 2.686 ± 0.254
1.49PhePro: 1.49 ± 0.222
1.431PheGln: 1.431 ± 0.178
1.804PheArg: 1.804 ± 0.203
3.51PheSer: 3.51 ± 0.362
2.353PheThr: 2.353 ± 0.195
3.726PheVal: 3.726 ± 0.31
0.392PheTrp: 0.392 ± 0.095
2.255PheTyr: 2.255 ± 0.241
0.0PheXaa: 0.0 ± 0.0
Gly
4.824GlyAla: 4.824 ± 0.521
1.0GlyCys: 1.0 ± 0.165
4.333GlyAsp: 4.333 ± 0.37
3.373GlyGlu: 3.373 ± 0.272
2.902GlyPhe: 2.902 ± 0.257
5.196GlyGly: 5.196 ± 0.544
1.49GlyHis: 1.49 ± 0.193
3.745GlyIle: 3.745 ± 0.363
4.0GlyLys: 4.0 ± 0.292
4.569GlyLeu: 4.569 ± 0.332
1.49GlyMet: 1.49 ± 0.169
3.235GlyAsn: 3.235 ± 0.533
1.941GlyPro: 1.941 ± 0.187
2.137GlyGln: 2.137 ± 0.225
2.765GlyArg: 2.765 ± 0.21
3.667GlySer: 3.667 ± 0.418
4.588GlyThr: 4.588 ± 0.593
4.667GlyVal: 4.667 ± 0.396
0.863GlyTrp: 0.863 ± 0.134
2.451GlyTyr: 2.451 ± 0.362
0.0GlyXaa: 0.0 ± 0.0
His
1.098HisAla: 1.098 ± 0.151
0.294HisCys: 0.294 ± 0.077
1.039HisAsp: 1.039 ± 0.164
1.216HisGlu: 1.216 ± 0.157
0.922HisPhe: 0.922 ± 0.141
1.451HisGly: 1.451 ± 0.186
0.333HisHis: 0.333 ± 0.086
1.353HisIle: 1.353 ± 0.17
1.314HisLys: 1.314 ± 0.202
2.02HisLeu: 2.02 ± 0.179
0.745HisMet: 0.745 ± 0.122
1.176HisAsn: 1.176 ± 0.156
1.176HisPro: 1.176 ± 0.184
0.686HisGln: 0.686 ± 0.11
1.098HisArg: 1.098 ± 0.154
1.157HisSer: 1.157 ± 0.158
1.392HisThr: 1.392 ± 0.2
1.843HisVal: 1.843 ± 0.232
0.373HisTrp: 0.373 ± 0.087
0.98HisTyr: 0.98 ± 0.134
0.0HisXaa: 0.0 ± 0.0
Ile
3.51IleAla: 3.51 ± 0.309
0.824IleCys: 0.824 ± 0.114
3.726IleAsp: 3.726 ± 0.289
3.353IleGlu: 3.353 ± 0.314
2.549IlePhe: 2.549 ± 0.298
3.451IleGly: 3.451 ± 0.301
1.196IleHis: 1.196 ± 0.173
3.471IleIle: 3.471 ± 0.386
3.922IleLys: 3.922 ± 0.29
4.902IleLeu: 4.902 ± 0.331
1.216IleMet: 1.216 ± 0.168
3.059IleAsn: 3.059 ± 0.282
2.471IlePro: 2.471 ± 0.24
2.49IleGln: 2.49 ± 0.22
2.902IleArg: 2.902 ± 0.278
3.588IleSer: 3.588 ± 0.308
3.471IleThr: 3.471 ± 0.353
3.588IleVal: 3.588 ± 0.319
0.471IleTrp: 0.471 ± 0.153
2.333IleTyr: 2.333 ± 0.185
0.0IleXaa: 0.0 ± 0.0
Lys
3.922LysAla: 3.922 ± 0.481
1.157LysCys: 1.157 ± 0.189
3.314LysAsp: 3.314 ± 0.278
4.333LysGlu: 4.333 ± 0.41
3.314LysPhe: 3.314 ± 0.323
2.843LysGly: 2.843 ± 0.234
1.353LysHis: 1.353 ± 0.168
4.02LysIle: 4.02 ± 0.287
6.196LysLys: 6.196 ± 0.707
5.118LysLeu: 5.118 ± 0.424
2.039LysMet: 2.039 ± 0.234
4.118LysAsn: 4.118 ± 0.447
2.451LysPro: 2.451 ± 0.233
2.451LysGln: 2.451 ± 0.31
3.078LysArg: 3.078 ± 0.329
3.961LysSer: 3.961 ± 0.315
3.784LysThr: 3.784 ± 0.293
5.118LysVal: 5.118 ± 0.392
0.667LysTrp: 0.667 ± 0.137
3.275LysTyr: 3.275 ± 0.334
0.0LysXaa: 0.0 ± 0.0
Leu
5.0LeuAla: 5.0 ± 0.288
1.294LeuCys: 1.294 ± 0.199
4.726LeuAsp: 4.726 ± 0.332
5.294LeuGlu: 5.294 ± 0.381
3.451LeuPhe: 3.451 ± 0.301
4.333LeuGly: 4.333 ± 0.356
1.745LeuHis: 1.745 ± 0.208
4.235LeuIle: 4.235 ± 0.413
5.824LeuLys: 5.824 ± 0.465
6.981LeuLeu: 6.981 ± 0.412
2.137LeuMet: 2.137 ± 0.231
4.294LeuAsn: 4.294 ± 0.565
3.608LeuPro: 3.608 ± 0.292
3.059LeuGln: 3.059 ± 0.284
4.588LeuArg: 4.588 ± 0.413
5.941LeuSer: 5.941 ± 0.364
5.235LeuThr: 5.235 ± 0.346
5.961LeuVal: 5.961 ± 0.423
0.922LeuTrp: 0.922 ± 0.139
3.608LeuTyr: 3.608 ± 0.229
0.0LeuXaa: 0.0 ± 0.0
Met
1.529MetAla: 1.529 ± 0.214
0.706MetCys: 0.706 ± 0.126
1.353MetAsp: 1.353 ± 0.153
1.706MetGlu: 1.706 ± 0.207
1.412MetPhe: 1.412 ± 0.196
1.275MetGly: 1.275 ± 0.152
0.549MetHis: 0.549 ± 0.109
1.235MetIle: 1.235 ± 0.146
2.726MetLys: 2.726 ± 0.281
2.02MetLeu: 2.02 ± 0.232
0.941MetMet: 0.941 ± 0.155
1.922MetAsn: 1.922 ± 0.249
0.902MetPro: 0.902 ± 0.135
0.902MetGln: 0.902 ± 0.14
1.529MetArg: 1.529 ± 0.151
2.157MetSer: 2.157 ± 0.245
1.824MetThr: 1.824 ± 0.205
1.098MetVal: 1.098 ± 0.135
0.471MetTrp: 0.471 ± 0.1
1.373MetTyr: 1.373 ± 0.165
0.0MetXaa: 0.0 ± 0.0
Asn
3.98AsnAla: 3.98 ± 0.583
0.726AsnCys: 0.726 ± 0.137
2.765AsnAsp: 2.765 ± 0.302
2.549AsnGlu: 2.549 ± 0.345
2.549AsnPhe: 2.549 ± 0.289
3.02AsnGly: 3.02 ± 0.258
0.863AsnHis: 0.863 ± 0.103
4.647AsnIle: 4.647 ± 0.78
3.667AsnLys: 3.667 ± 0.557
4.961AsnLeu: 4.961 ± 0.768
1.706AsnMet: 1.706 ± 0.206
3.216AsnAsn: 3.216 ± 0.46
2.275AsnPro: 2.275 ± 0.254
1.412AsnGln: 1.412 ± 0.175
2.294AsnArg: 2.294 ± 0.337
3.02AsnSer: 3.02 ± 0.331
4.059AsnThr: 4.059 ± 0.52
5.53AsnVal: 5.53 ± 0.991
0.627AsnTrp: 0.627 ± 0.132
2.216AsnTyr: 2.216 ± 0.181
0.0AsnXaa: 0.0 ± 0.0
Pro
2.608ProAla: 2.608 ± 0.27
0.726ProCys: 0.726 ± 0.137
2.098ProAsp: 2.098 ± 0.21
3.608ProGlu: 3.608 ± 0.353
1.706ProPhe: 1.706 ± 0.161
2.549ProGly: 2.549 ± 0.229
0.843ProHis: 0.843 ± 0.139
1.686ProIle: 1.686 ± 0.164
2.569ProLys: 2.569 ± 0.236
2.98ProLeu: 2.98 ± 0.277
1.333ProMet: 1.333 ± 0.185
1.51ProAsn: 1.51 ± 0.154
2.628ProPro: 2.628 ± 0.308
1.765ProGln: 1.765 ± 0.166
1.745ProArg: 1.745 ± 0.201
2.882ProSer: 2.882 ± 0.245
3.02ProThr: 3.02 ± 0.271
3.157ProVal: 3.157 ± 0.288
0.451ProTrp: 0.451 ± 0.108
1.471ProTyr: 1.471 ± 0.168
0.0ProXaa: 0.0 ± 0.0
Gln
2.0GlnAla: 2.0 ± 0.257
0.608GlnCys: 0.608 ± 0.099
1.784GlnAsp: 1.784 ± 0.203
2.431GlnGlu: 2.431 ± 0.28
1.333GlnPhe: 1.333 ± 0.156
1.902GlnGly: 1.902 ± 0.224
0.882GlnHis: 0.882 ± 0.143
1.549GlnIle: 1.549 ± 0.137
2.667GlnLys: 2.667 ± 0.314
3.255GlnLeu: 3.255 ± 0.276
1.137GlnMet: 1.137 ± 0.16
1.941GlnAsn: 1.941 ± 0.215
1.745GlnPro: 1.745 ± 0.2
1.451GlnGln: 1.451 ± 0.169
2.059GlnArg: 2.059 ± 0.286
1.98GlnSer: 1.98 ± 0.197
1.882GlnThr: 1.882 ± 0.215
2.706GlnVal: 2.706 ± 0.255
0.49GlnTrp: 0.49 ± 0.12
1.392GlnTyr: 1.392 ± 0.163
0.0GlnXaa: 0.0 ± 0.0
Arg
3.49ArgAla: 3.49 ± 0.52
1.0ArgCys: 1.0 ± 0.161
2.902ArgAsp: 2.902 ± 0.293
3.647ArgGlu: 3.647 ± 0.402
1.922ArgPhe: 1.922 ± 0.169
2.745ArgGly: 2.745 ± 0.291
1.412ArgHis: 1.412 ± 0.201
2.745ArgIle: 2.745 ± 0.241
3.02ArgLys: 3.02 ± 0.473
3.824ArgLeu: 3.824 ± 0.269
1.549ArgMet: 1.549 ± 0.169
2.157ArgAsn: 2.157 ± 0.263
1.686ArgPro: 1.686 ± 0.192
1.784ArgGln: 1.784 ± 0.186
2.686ArgArg: 2.686 ± 0.371
2.294ArgSer: 2.294 ± 0.242
2.549ArgThr: 2.549 ± 0.245
4.431ArgVal: 4.431 ± 0.321
0.667ArgTrp: 0.667 ± 0.127
2.235ArgTyr: 2.235 ± 0.24
0.0ArgXaa: 0.0 ± 0.0
Ser
3.451SerAla: 3.451 ± 0.321
0.902SerCys: 0.902 ± 0.165
3.569SerAsp: 3.569 ± 0.288
3.51SerGlu: 3.51 ± 0.276
2.745SerPhe: 2.745 ± 0.293
5.079SerGly: 5.079 ± 0.536
1.196SerHis: 1.196 ± 0.161
3.098SerIle: 3.098 ± 0.245
3.353SerLys: 3.353 ± 0.321
4.314SerLeu: 4.314 ± 0.32
1.333SerMet: 1.333 ± 0.161
5.549SerAsn: 5.549 ± 1.4
2.098SerPro: 2.098 ± 0.239
2.196SerGln: 2.196 ± 0.205
2.588SerArg: 2.588 ± 0.28
4.549SerSer: 4.549 ± 0.469
4.314SerThr: 4.314 ± 0.479
4.196SerVal: 4.196 ± 0.332
0.765SerTrp: 0.765 ± 0.122
2.137SerTyr: 2.137 ± 0.2
0.0SerXaa: 0.0 ± 0.0
Thr
4.255ThrAla: 4.255 ± 0.492
1.118ThrCys: 1.118 ± 0.193
3.667ThrAsp: 3.667 ± 0.291
3.275ThrGlu: 3.275 ± 0.285
2.686ThrPhe: 2.686 ± 0.243
5.235ThrGly: 5.235 ± 0.568
1.255ThrHis: 1.255 ± 0.142
3.275ThrIle: 3.275 ± 0.29
4.059ThrLys: 4.059 ± 0.295
6.412ThrLeu: 6.412 ± 0.417
1.529ThrMet: 1.529 ± 0.179
3.882ThrAsn: 3.882 ± 0.47
3.196ThrPro: 3.196 ± 0.251
2.059ThrGln: 2.059 ± 0.208
2.784ThrArg: 2.784 ± 0.203
4.628ThrSer: 4.628 ± 0.46
5.726ThrThr: 5.726 ± 0.789
2.412ThrVal: 2.412 ± 0.347
1.078ThrTrp: 1.078 ± 0.184
3.039ThrTyr: 3.039 ± 0.25
0.0ThrXaa: 0.0 ± 0.0
Val
5.235ValAla: 5.235 ± 0.38
1.471ValCys: 1.471 ± 0.206
4.569ValAsp: 4.569 ± 0.34
4.431ValGlu: 4.431 ± 0.297
3.118ValPhe: 3.118 ± 0.295
4.98ValGly: 4.98 ± 0.493
1.98ValHis: 1.98 ± 0.223
3.922ValIle: 3.922 ± 0.348
4.392ValLys: 4.392 ± 0.357
5.843ValLeu: 5.843 ± 0.43
1.588ValMet: 1.588 ± 0.167
4.02ValAsn: 4.02 ± 0.515
3.0ValPro: 3.0 ± 0.243
2.745ValGln: 2.745 ± 0.207
3.588ValArg: 3.588 ± 0.261
4.706ValSer: 4.706 ± 0.306
4.373ValThr: 4.373 ± 0.436
5.333ValVal: 5.333 ± 0.361
0.529ValTrp: 0.529 ± 0.113
3.255ValTyr: 3.255 ± 0.301
0.0ValXaa: 0.0 ± 0.0
Trp
0.471TrpAla: 0.471 ± 0.09
0.275TrpCys: 0.275 ± 0.082
0.686TrpAsp: 0.686 ± 0.119
0.608TrpGlu: 0.608 ± 0.109
0.647TrpPhe: 0.647 ± 0.116
0.588TrpGly: 0.588 ± 0.105
0.255TrpHis: 0.255 ± 0.069
0.392TrpIle: 0.392 ± 0.099
0.882TrpLys: 0.882 ± 0.147
1.118TrpLeu: 1.118 ± 0.179
0.314TrpMet: 0.314 ± 0.069
0.667TrpAsn: 0.667 ± 0.156
0.333TrpPro: 0.333 ± 0.074
0.431TrpGln: 0.431 ± 0.096
0.529TrpArg: 0.529 ± 0.121
0.882TrpSer: 0.882 ± 0.162
0.922TrpThr: 0.922 ± 0.162
0.961TrpVal: 0.961 ± 0.174
0.294TrpTrp: 0.294 ± 0.081
0.373TrpTyr: 0.373 ± 0.093
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.941TyrAla: 2.941 ± 0.21
0.549TyrCys: 0.549 ± 0.101
2.706TyrAsp: 2.706 ± 0.267
2.51TyrGlu: 2.51 ± 0.224
1.922TyrPhe: 1.922 ± 0.181
2.824TyrGly: 2.824 ± 0.302
1.137TyrHis: 1.137 ± 0.169
2.706TyrIle: 2.706 ± 0.383
3.059TyrLys: 3.059 ± 0.313
3.588TyrLeu: 3.588 ± 0.251
1.255TyrMet: 1.255 ± 0.159
2.078TyrAsn: 2.078 ± 0.191
1.686TyrPro: 1.686 ± 0.168
1.216TyrGln: 1.216 ± 0.162
1.667TyrArg: 1.667 ± 0.194
2.314TyrSer: 2.314 ± 0.234
3.137TyrThr: 3.137 ± 0.357
2.902TyrVal: 2.902 ± 0.232
0.314TyrTrp: 0.314 ± 0.095
1.706TyrTyr: 1.706 ± 0.184
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 188 proteins (51000 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski