Amino acid dipepetide frequency for Stenotrophomonas daejeonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.11AlaAla: 19.11 ± 0.21	1.274AlaCys: 1.274 ± 0.037	7.409AlaAsp: 7.409 ± 0.101	7.248AlaGlu: 7.248 ± 0.096	3.999AlaPhe: 3.999 ± 0.065	12.152AlaGly: 12.152 ± 0.139	2.589AlaHis: 2.589 ± 0.062	5.191AlaIle: 5.191 ± 0.089	3.0AlaLys: 3.0 ± 0.076	16.01AlaLeu: 16.01 ± 0.184	3.381AlaMet: 3.381 ± 0.053	2.934AlaAsn: 2.934 ± 0.069	6.352AlaPro: 6.352 ± 0.103	5.538AlaGln: 5.538 ± 0.09	10.222AlaArg: 10.222 ± 0.131	6.143AlaSer: 6.143 ± 0.092	6.203AlaThr: 6.203 ± 0.087	8.591AlaVal: 8.591 ± 0.112	2.06AlaTrp: 2.06 ± 0.054	2.392AlaTyr: 2.392 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.982CysAla: 0.982 ± 0.029	0.098CysCys: 0.098 ± 0.01	0.45CysAsp: 0.45 ± 0.022	0.418CysGlu: 0.418 ± 0.023	0.294CysPhe: 0.294 ± 0.019	0.915CysGly: 0.915 ± 0.034	0.234CysHis: 0.234 ± 0.017	0.36CysIle: 0.36 ± 0.022	0.17CysLys: 0.17 ± 0.013	0.799CysLeu: 0.799 ± 0.033	0.169CysMet: 0.169 ± 0.014	0.22CysAsn: 0.22 ± 0.018	0.394CysPro: 0.394 ± 0.021	0.226CysGln: 0.226 ± 0.014	0.601CysArg: 0.601 ± 0.024	0.422CysSer: 0.422 ± 0.021	0.438CysThr: 0.438 ± 0.021	0.626CysVal: 0.626 ± 0.024	0.125CysTrp: 0.125 ± 0.012	0.178CysTyr: 0.178 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	8.717AspAla: 8.717 ± 0.125	0.429AspCys: 0.429 ± 0.021	3.574AspAsp: 3.574 ± 0.074	3.463AspGlu: 3.463 ± 0.066	2.153AspPhe: 2.153 ± 0.048	6.15AspGly: 6.15 ± 0.095	1.133AspHis: 1.133 ± 0.041	2.302AspIle: 2.302 ± 0.054	1.623AspLys: 1.623 ± 0.052	5.264AspLeu: 5.264 ± 0.079	1.194AspMet: 1.194 ± 0.04	1.489AspAsn: 1.489 ± 0.048	3.215AspPro: 3.215 ± 0.07	1.461AspGln: 1.461 ± 0.042	3.502AspArg: 3.502 ± 0.07	2.42AspSer: 2.42 ± 0.051	2.729AspThr: 2.729 ± 0.054	4.302AspVal: 4.302 ± 0.067	1.139AspTrp: 1.139 ± 0.037	1.753AspTyr: 1.753 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	7.135GluAla: 7.135 ± 0.113	0.338GluCys: 0.338 ± 0.022	2.467GluAsp: 2.467 ± 0.06	2.585GluGlu: 2.585 ± 0.059	1.689GluPhe: 1.689 ± 0.044	4.06GluGly: 4.06 ± 0.069	1.38GluHis: 1.38 ± 0.035	2.407GluIle: 2.407 ± 0.053	1.697GluLys: 1.697 ± 0.048	6.6GluLeu: 6.6 ± 0.091	1.165GluMet: 1.165 ± 0.036	1.255GluAsn: 1.255 ± 0.042	2.531GluPro: 2.531 ± 0.056	3.061GluGln: 3.061 ± 0.067	5.205GluArg: 5.205 ± 0.086	2.341GluSer: 2.341 ± 0.049	2.524GluThr: 2.524 ± 0.055	4.074GluVal: 4.074 ± 0.082	0.676GluTrp: 0.676 ± 0.027	1.115GluTyr: 1.115 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.277PheAla: 4.277 ± 0.079	0.336PheCys: 0.336 ± 0.02	2.774PheAsp: 2.774 ± 0.057	1.903PheGlu: 1.903 ± 0.05	1.181PhePhe: 1.181 ± 0.044	3.387PheGly: 3.387 ± 0.063	0.792PheHis: 0.792 ± 0.033	1.263PheIle: 1.263 ± 0.045	0.908PheLys: 0.908 ± 0.032	2.928PheLeu: 2.928 ± 0.057	0.688PheMet: 0.688 ± 0.027	1.096PheAsn: 1.096 ± 0.032	1.458PhePro: 1.458 ± 0.036	0.95PheGln: 0.95 ± 0.031	2.146PheArg: 2.146 ± 0.048	1.864PheSer: 1.864 ± 0.046	1.678PheThr: 1.678 ± 0.05	2.522PheVal: 2.522 ± 0.054	0.513PheTrp: 0.513 ± 0.025	0.801PheTyr: 0.801 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	8.992GlyAla: 8.992 ± 0.113	0.845GlyCys: 0.845 ± 0.029	4.966GlyAsp: 4.966 ± 0.077	5.072GlyGlu: 5.072 ± 0.08	3.479GlyPhe: 3.479 ± 0.063	7.526GlyGly: 7.526 ± 0.122	2.279GlyHis: 2.279 ± 0.053	4.324GlyIle: 4.324 ± 0.057	3.281GlyLys: 3.281 ± 0.067	9.033GlyLeu: 9.033 ± 0.125	2.489GlyMet: 2.489 ± 0.053	2.796GlyAsn: 2.796 ± 0.06	2.994GlyPro: 2.994 ± 0.055	3.532GlyGln: 3.532 ± 0.068	6.397GlyArg: 6.397 ± 0.093	4.708GlySer: 4.708 ± 0.087	4.393GlyThr: 4.393 ± 0.081	6.561GlyVal: 6.561 ± 0.09	1.803GlyTrp: 1.803 ± 0.041	2.376GlyTyr: 2.376 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	3.304HisAla: 3.304 ± 0.071	0.257HisCys: 0.257 ± 0.015	1.45HisAsp: 1.45 ± 0.046	1.217HisGlu: 1.217 ± 0.038	0.82HisPhe: 0.82 ± 0.032	2.49HisGly: 2.49 ± 0.057	0.615HisHis: 0.615 ± 0.029	0.749HisIle: 0.749 ± 0.029	0.485HisLys: 0.485 ± 0.023	2.242HisLeu: 2.242 ± 0.053	0.463HisMet: 0.463 ± 0.022	0.518HisAsn: 0.518 ± 0.022	1.461HisPro: 1.461 ± 0.044	0.608HisGln: 0.608 ± 0.023	1.662HisArg: 1.662 ± 0.045	0.939HisSer: 0.939 ± 0.028	0.913HisThr: 0.913 ± 0.033	1.647HisVal: 1.647 ± 0.044	0.467HisTrp: 0.467 ± 0.023	0.663HisTyr: 0.663 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.229IleAla: 6.229 ± 0.101	0.304IleCys: 0.304 ± 0.019	3.303IleAsp: 3.303 ± 0.056	2.793IleGlu: 2.793 ± 0.057	1.024IlePhe: 1.024 ± 0.036	4.36IleGly: 4.36 ± 0.076	0.901IleHis: 0.901 ± 0.029	1.295IleIle: 1.295 ± 0.047	1.124IleLys: 1.124 ± 0.044	2.846IleLeu: 2.846 ± 0.058	0.524IleMet: 0.524 ± 0.026	1.203IleAsn: 1.203 ± 0.04	1.963IlePro: 1.963 ± 0.049	0.972IleGln: 0.972 ± 0.03	2.553IleArg: 2.553 ± 0.06	1.961IleSer: 1.961 ± 0.052	2.057IleThr: 2.057 ± 0.052	3.171IleVal: 3.171 ± 0.061	0.406IleTrp: 0.406 ± 0.024	0.718IleTyr: 0.718 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.353LysAla: 3.353 ± 0.083	0.123LysCys: 0.123 ± 0.013	1.464LysAsp: 1.464 ± 0.045	1.212LysGlu: 1.212 ± 0.041	0.719LysPhe: 0.719 ± 0.029	2.066LysGly: 2.066 ± 0.053	0.586LysHis: 0.586 ± 0.025	1.137LysIle: 1.137 ± 0.038	0.943LysLys: 0.943 ± 0.047	3.146LysLeu: 3.146 ± 0.06	0.584LysMet: 0.584 ± 0.028	0.691LysAsn: 0.691 ± 0.028	1.848LysPro: 1.848 ± 0.057	1.226LysGln: 1.226 ± 0.037	2.086LysArg: 2.086 ± 0.046	1.236LysSer: 1.236 ± 0.04	1.348LysThr: 1.348 ± 0.043	2.335LysVal: 2.335 ± 0.06	0.282LysTrp: 0.282 ± 0.017	0.626LysTyr: 0.626 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	15.761LeuAla: 15.761 ± 0.171	0.967LeuCys: 0.967 ± 0.03	7.067LeuAsp: 7.067 ± 0.097	5.689LeuGlu: 5.689 ± 0.09	3.589LeuPhe: 3.589 ± 0.072	8.934LeuGly: 8.934 ± 0.118	2.747LeuHis: 2.747 ± 0.061	3.416LeuIle: 3.416 ± 0.071	3.06LeuLys: 3.06 ± 0.065	13.41LeuLeu: 13.41 ± 0.206	2.126LeuMet: 2.126 ± 0.052	2.321LeuAsn: 2.321 ± 0.048	7.166LeuPro: 7.166 ± 0.11	4.604LeuGln: 4.604 ± 0.088	9.274LeuArg: 9.274 ± 0.122	5.703LeuSer: 5.703 ± 0.091	4.379LeuThr: 4.379 ± 0.071	7.998LeuVal: 7.998 ± 0.11	1.523LeuTrp: 1.523 ± 0.05	2.278LeuTyr: 2.278 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.9MetAla: 2.9 ± 0.056	0.147MetCys: 0.147 ± 0.015	1.113MetAsp: 1.113 ± 0.035	0.94MetGlu: 0.94 ± 0.03	0.625MetPhe: 0.625 ± 0.028	1.579MetGly: 1.579 ± 0.046	0.465MetHis: 0.465 ± 0.025	0.873MetIle: 0.873 ± 0.037	0.838MetLys: 0.838 ± 0.035	2.528MetLeu: 2.528 ± 0.051	0.493MetMet: 0.493 ± 0.022	0.81MetAsn: 0.81 ± 0.028	1.451MetPro: 1.451 ± 0.035	1.044MetGln: 1.044 ± 0.035	1.724MetArg: 1.724 ± 0.05	1.314MetSer: 1.314 ± 0.039	1.296MetThr: 1.296 ± 0.033	1.531MetVal: 1.531 ± 0.037	0.223MetTrp: 0.223 ± 0.015	0.336MetTyr: 0.336 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.296AsnAla: 3.296 ± 0.07	0.194AsnCys: 0.194 ± 0.013	1.52AsnAsp: 1.52 ± 0.047	1.17AsnGlu: 1.17 ± 0.034	0.901AsnPhe: 0.901 ± 0.033	2.436AsnGly: 2.436 ± 0.054	0.591AsnHis: 0.591 ± 0.025	1.11AsnIle: 1.11 ± 0.037	0.663AsnLys: 0.663 ± 0.027	2.647AsnLeu: 2.647 ± 0.07	0.419AsnMet: 0.419 ± 0.022	0.663AsnAsn: 0.663 ± 0.037	1.823AsnPro: 1.823 ± 0.055	0.777AsnGln: 0.777 ± 0.027	1.833AsnArg: 1.833 ± 0.046	1.053AsnSer: 1.053 ± 0.036	1.348AsnThr: 1.348 ± 0.043	1.913AsnVal: 1.913 ± 0.046	0.404AsnTrp: 0.404 ± 0.023	0.665AsnTyr: 0.665 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	7.899ProAla: 7.899 ± 0.111	0.347ProCys: 0.347 ± 0.019	3.255ProAsp: 3.255 ± 0.057	3.408ProGlu: 3.408 ± 0.069	1.686ProPhe: 1.686 ± 0.043	4.935ProGly: 4.935 ± 0.075	1.084ProHis: 1.084 ± 0.038	1.649ProIle: 1.649 ± 0.042	1.229ProLys: 1.229 ± 0.043	5.867ProLeu: 5.867 ± 0.1	1.281ProMet: 1.281 ± 0.037	1.057ProAsn: 1.057 ± 0.034	2.807ProPro: 2.807 ± 0.074	2.3ProGln: 2.3 ± 0.053	3.566ProArg: 3.566 ± 0.071	2.41ProSer: 2.41 ± 0.054	2.172ProThr: 2.172 ± 0.051	4.394ProVal: 4.394 ± 0.084	0.857ProTrp: 0.857 ± 0.037	1.132ProTyr: 1.132 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	5.957GlnAla: 5.957 ± 0.094	0.26GlnCys: 0.26 ± 0.016	1.538GlnAsp: 1.538 ± 0.048	1.594GlnGlu: 1.594 ± 0.039	1.165GlnPhe: 1.165 ± 0.034	2.998GlnGly: 2.998 ± 0.054	0.879GlnHis: 0.879 ± 0.034	1.397GlnIle: 1.397 ± 0.044	0.932GlnLys: 0.932 ± 0.04	4.825GlnLeu: 4.825 ± 0.078	0.856GlnMet: 0.856 ± 0.029	0.752GlnAsn: 0.752 ± 0.038	2.515GlnPro: 2.515 ± 0.056	2.189GlnGln: 2.189 ± 0.051	3.868GlnArg: 3.868 ± 0.069	1.641GlnSer: 1.641 ± 0.044	1.436GlnThr: 1.436 ± 0.042	3.383GlnVal: 3.383 ± 0.058	0.743GlnTrp: 0.743 ± 0.031	0.806GlnTyr: 0.806 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	8.412ArgAla: 8.412 ± 0.118	0.541ArgCys: 0.541 ± 0.029	4.524ArgAsp: 4.524 ± 0.076	4.945ArgGlu: 4.945 ± 0.083	2.902ArgPhe: 2.902 ± 0.059	5.677ArgGly: 5.677 ± 0.075	2.133ArgHis: 2.133 ± 0.049	3.848ArgIle: 3.848 ± 0.061	2.024ArgLys: 2.024 ± 0.048	8.783ArgLeu: 8.783 ± 0.13	2.018ArgMet: 2.018 ± 0.047	2.141ArgAsn: 2.141 ± 0.048	3.469ArgPro: 3.469 ± 0.069	3.537ArgGln: 3.537 ± 0.066	6.318ArgArg: 6.318 ± 0.097	3.529ArgSer: 3.529 ± 0.059	3.173ArgThr: 3.173 ± 0.062	5.243ArgVal: 5.243 ± 0.085	1.519ArgTrp: 1.519 ± 0.046	2.158ArgTyr: 2.158 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	5.838SerAla: 5.838 ± 0.076	0.362SerCys: 0.362 ± 0.022	2.506SerAsp: 2.506 ± 0.053	2.32SerGlu: 2.32 ± 0.051	1.75SerPhe: 1.75 ± 0.049	4.939SerGly: 4.939 ± 0.084	1.089SerHis: 1.089 ± 0.036	2.111SerIle: 2.111 ± 0.055	1.21SerLys: 1.21 ± 0.04	5.19SerLeu: 5.19 ± 0.076	1.079SerMet: 1.079 ± 0.035	1.32SerAsn: 1.32 ± 0.035	2.65SerPro: 2.65 ± 0.052	1.658SerGln: 1.658 ± 0.043	3.596SerArg: 3.596 ± 0.068	2.582SerSer: 2.582 ± 0.067	2.357SerThr: 2.357 ± 0.053	3.536SerVal: 3.536 ± 0.067	0.767SerTrp: 0.767 ± 0.025	1.215SerTyr: 1.215 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.647ThrAla: 5.647 ± 0.1	0.365ThrCys: 0.365 ± 0.02	2.409ThrAsp: 2.409 ± 0.054	2.042ThrGlu: 2.042 ± 0.045	1.466ThrPhe: 1.466 ± 0.038	4.61ThrGly: 4.61 ± 0.091	1.024ThrHis: 1.024 ± 0.034	1.763ThrIle: 1.763 ± 0.05	0.847ThrLys: 0.847 ± 0.036	6.149ThrLeu: 6.149 ± 0.097	0.847ThrMet: 0.847 ± 0.031	0.983ThrAsn: 0.983 ± 0.043	3.272ThrPro: 3.272 ± 0.057	1.468ThrGln: 1.468 ± 0.041	3.415ThrArg: 3.415 ± 0.064	2.111ThrSer: 2.111 ± 0.05	2.419ThrThr: 2.419 ± 0.072	3.699ThrVal: 3.699 ± 0.076	0.661ThrTrp: 0.661 ± 0.027	0.985ThrTyr: 0.985 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	9.948ValAla: 9.948 ± 0.122	0.591ValCys: 0.591 ± 0.027	4.193ValAsp: 4.193 ± 0.079	4.576ValGlu: 4.576 ± 0.076	2.625ValPhe: 2.625 ± 0.052	5.595ValGly: 5.595 ± 0.077	1.597ValHis: 1.597 ± 0.047	3.177ValIle: 3.177 ± 0.067	1.895ValLys: 1.895 ± 0.045	8.692ValLeu: 8.692 ± 0.119	1.618ValMet: 1.618 ± 0.043	1.97ValAsn: 1.97 ± 0.053	3.994ValPro: 3.994 ± 0.075	2.841ValGln: 2.841 ± 0.058	5.402ValArg: 5.402 ± 0.091	3.689ValSer: 3.689 ± 0.064	3.542ValThr: 3.542 ± 0.079	6.273ValVal: 6.273 ± 0.11	0.876ValTrp: 0.876 ± 0.031	1.425ValTyr: 1.425 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.3TrpAla: 1.3 ± 0.041	0.146TrpCys: 0.146 ± 0.014	0.668TrpAsp: 0.668 ± 0.027	0.605TrpGlu: 0.605 ± 0.026	0.586TrpPhe: 0.586 ± 0.025	0.951TrpGly: 0.951 ± 0.033	0.394TrpHis: 0.394 ± 0.023	0.636TrpIle: 0.636 ± 0.026	0.527TrpLys: 0.527 ± 0.025	2.512TrpLeu: 2.512 ± 0.07	0.445TrpMet: 0.445 ± 0.023	0.556TrpAsn: 0.556 ± 0.027	0.849TrpPro: 0.849 ± 0.031	0.911TrpGln: 0.911 ± 0.029	1.391TrpArg: 1.391 ± 0.042	0.868TrpSer: 0.868 ± 0.032	0.662TrpThr: 0.662 ± 0.028	1.058TrpVal: 1.058 ± 0.035	0.35TrpTrp: 0.35 ± 0.017	0.368TrpTyr: 0.368 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.74TyrAla: 2.74 ± 0.058	0.192TyrCys: 0.192 ± 0.013	1.363TyrAsp: 1.363 ± 0.049	1.108TyrGlu: 1.108 ± 0.036	0.816TyrPhe: 0.816 ± 0.034	2.084TyrGly: 2.084 ± 0.048	0.46TyrHis: 0.46 ± 0.025	0.7TyrIle: 0.7 ± 0.03	0.551TyrLys: 0.551 ± 0.027	2.538TyrLeu: 2.538 ± 0.054	0.394TyrMet: 0.394 ± 0.018	0.649TyrAsn: 0.649 ± 0.034	1.12TyrPro: 1.12 ± 0.035	0.834TyrGln: 0.834 ± 0.027	2.131TyrArg: 2.131 ± 0.056	1.142TyrSer: 1.142 ± 0.045	1.116TyrThr: 1.116 ± 0.044	1.662TyrVal: 1.662 ± 0.044	0.391TyrTrp: 0.391 ± 0.022	0.598TyrTyr: 0.598 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2805 proteins (929062 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---