Amino acid dipepetide frequency for Candidatus Rhabdochlamydia sp. T3358

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.802AlaAla: 4.802 ± 0.128
1.054AlaCys: 1.054 ± 0.044
2.84AlaAsp: 2.84 ± 0.078
3.821AlaGlu: 3.821 ± 0.096
3.488AlaPhe: 3.488 ± 0.077
3.679AlaGly: 3.679 ± 0.124
1.503AlaHis: 1.503 ± 0.054
5.652AlaIle: 5.652 ± 0.113
4.996AlaLys: 4.996 ± 0.089
8.268AlaLeu: 8.268 ± 0.155
1.486AlaMet: 1.486 ± 0.054
2.612AlaAsn: 2.612 ± 0.076
2.085AlaPro: 2.085 ± 0.065
2.933AlaGln: 2.933 ± 0.076
2.724AlaArg: 2.724 ± 0.082
4.385AlaSer: 4.385 ± 0.1
3.174AlaThr: 3.174 ± 0.07
3.883AlaVal: 3.883 ± 0.106
0.738AlaTrp: 0.738 ± 0.037
2.149AlaTyr: 2.149 ± 0.066
0.0AlaXaa: 0.0 ± 0.0
Cys
0.94CysAla: 0.94 ± 0.042
0.331CysCys: 0.331 ± 0.026
0.663CysAsp: 0.663 ± 0.036
0.643CysGlu: 0.643 ± 0.035
1.021CysPhe: 1.021 ± 0.038
0.918CysGly: 0.918 ± 0.048
0.377CysHis: 0.377 ± 0.025
1.253CysIle: 1.253 ± 0.051
0.874CysLys: 0.874 ± 0.046
1.859CysLeu: 1.859 ± 0.071
0.358CysMet: 0.358 ± 0.024
0.692CysAsn: 0.692 ± 0.039
0.654CysPro: 0.654 ± 0.035
0.547CysGln: 0.547 ± 0.031
0.582CysArg: 0.582 ± 0.033
1.183CysSer: 1.183 ± 0.053
0.602CysThr: 0.602 ± 0.039
0.781CysVal: 0.781 ± 0.042
0.149CysTrp: 0.149 ± 0.016
0.566CysTyr: 0.566 ± 0.035
0.0CysXaa: 0.0 ± 0.0
Asp
2.753AspAla: 2.753 ± 0.072
0.718AspCys: 0.718 ± 0.037
1.558AspAsp: 1.558 ± 0.059
2.559AspGlu: 2.559 ± 0.077
2.647AspPhe: 2.647 ± 0.073
2.074AspGly: 2.074 ± 0.068
1.091AspHis: 1.091 ± 0.045
3.233AspIle: 3.233 ± 0.083
3.071AspLys: 3.071 ± 0.08
6.255AspLeu: 6.255 ± 0.113
0.856AspMet: 0.856 ± 0.045
1.497AspAsn: 1.497 ± 0.066
2.676AspPro: 2.676 ± 0.079
2.333AspGln: 2.333 ± 0.07
2.153AspArg: 2.153 ± 0.07
2.818AspSer: 2.818 ± 0.079
2.063AspThr: 2.063 ± 0.061
2.55AspVal: 2.55 ± 0.077
0.637AspTrp: 0.637 ± 0.037
1.666AspTyr: 1.666 ± 0.056
0.0AspXaa: 0.0 ± 0.0
Glu
4.405GluAla: 4.405 ± 0.088
0.709GluCys: 0.709 ± 0.039
2.95GluAsp: 2.95 ± 0.094
6.078GluGlu: 6.078 ± 0.138
2.381GluPhe: 2.381 ± 0.069
3.466GluGly: 3.466 ± 0.079
1.295GluHis: 1.295 ± 0.046
5.781GluIle: 5.781 ± 0.106
6.868GluLys: 6.868 ± 0.152
6.442GluLeu: 6.442 ± 0.121
1.602GluMet: 1.602 ± 0.062
3.406GluAsn: 3.406 ± 0.096
1.747GluPro: 1.747 ± 0.061
3.233GluGln: 3.233 ± 0.085
2.775GluArg: 2.775 ± 0.075
3.529GluSer: 3.529 ± 0.084
3.099GluThr: 3.099 ± 0.083
3.676GluVal: 3.676 ± 0.084
0.639GluTrp: 0.639 ± 0.038
2.09GluTyr: 2.09 ± 0.065
0.0GluXaa: 0.0 ± 0.0
Phe
3.119PheAla: 3.119 ± 0.087
1.172PheCys: 1.172 ± 0.055
2.491PheAsp: 2.491 ± 0.07
2.84PheGlu: 2.84 ± 0.081
3.501PhePhe: 3.501 ± 0.094
2.693PheGly: 2.693 ± 0.074
1.176PheHis: 1.176 ± 0.05
3.841PheIle: 3.841 ± 0.098
2.731PheLys: 2.731 ± 0.078
5.894PheLeu: 5.894 ± 0.133
1.097PheMet: 1.097 ± 0.044
2.017PheAsn: 2.017 ± 0.062
2.252PhePro: 2.252 ± 0.067
1.942PheGln: 1.942 ± 0.055
1.686PheArg: 1.686 ± 0.055
4.888PheSer: 4.888 ± 0.108
2.697PheThr: 2.697 ± 0.072
2.417PheVal: 2.417 ± 0.074
0.604PheTrp: 0.604 ± 0.036
1.991PheTyr: 1.991 ± 0.066
0.0PheXaa: 0.0 ± 0.0
Gly
3.554GlyAla: 3.554 ± 0.13
0.904GlyCys: 0.904 ± 0.046
2.134GlyAsp: 2.134 ± 0.07
2.426GlyGlu: 2.426 ± 0.075
3.27GlyPhe: 3.27 ± 0.091
3.642GlyGly: 3.642 ± 0.23
1.223GlyHis: 1.223 ± 0.056
4.853GlyIle: 4.853 ± 0.113
4.276GlyLys: 4.276 ± 0.098
6.018GlyLeu: 6.018 ± 0.131
1.486GlyMet: 1.486 ± 0.055
2.269GlyAsn: 2.269 ± 0.095
1.659GlyPro: 1.659 ± 0.06
1.826GlyGln: 1.826 ± 0.061
2.434GlyArg: 2.434 ± 0.075
3.887GlySer: 3.887 ± 0.126
2.937GlyThr: 2.937 ± 0.128
3.492GlyVal: 3.492 ± 0.099
0.766GlyTrp: 0.766 ± 0.038
2.131GlyTyr: 2.131 ± 0.068
0.0GlyXaa: 0.0 ± 0.0
His
1.433HisAla: 1.433 ± 0.046
0.384HisCys: 0.384 ± 0.023
0.828HisAsp: 0.828 ± 0.036
1.179HisGlu: 1.179 ± 0.055
1.499HisPhe: 1.499 ± 0.051
1.058HisGly: 1.058 ± 0.049
0.584HisHis: 0.584 ± 0.036
1.703HisIle: 1.703 ± 0.065
1.482HisLys: 1.482 ± 0.058
3.33HisLeu: 3.33 ± 0.093
0.441HisMet: 0.441 ± 0.028
0.847HisAsn: 0.847 ± 0.041
1.477HisPro: 1.477 ± 0.056
1.038HisGln: 1.038 ± 0.044
1.089HisArg: 1.089 ± 0.049
1.657HisSer: 1.657 ± 0.059
1.21HisThr: 1.21 ± 0.046
1.315HisVal: 1.315 ± 0.05
0.314HisTrp: 0.314 ± 0.027
0.871HisTyr: 0.871 ± 0.04
0.0HisXaa: 0.0 ± 0.0
Ile
6.313IleAla: 6.313 ± 0.123
1.481IleCys: 1.481 ± 0.05
4.482IleAsp: 4.482 ± 0.099
5.806IleGlu: 5.806 ± 0.106
3.714IlePhe: 3.714 ± 0.091
4.719IleGly: 4.719 ± 0.125
1.953IleHis: 1.953 ± 0.07
5.195IleIle: 5.195 ± 0.12
5.051IleLys: 5.051 ± 0.129
7.933IleLeu: 7.933 ± 0.144
1.166IleMet: 1.166 ± 0.053
3.395IleAsn: 3.395 ± 0.077
3.841IlePro: 3.841 ± 0.081
3.541IleGln: 3.541 ± 0.082
2.985IleArg: 2.985 ± 0.078
5.718IleSer: 5.718 ± 0.103
4.109IleThr: 4.109 ± 0.101
3.986IleVal: 3.986 ± 0.098
0.88IleTrp: 0.88 ± 0.045
2.612IleTyr: 2.612 ± 0.081
0.0IleXaa: 0.0 ± 0.0
Lys
4.842LysAla: 4.842 ± 0.099
0.582LysCys: 0.582 ± 0.03
3.62LysAsp: 3.62 ± 0.108
6.892LysGlu: 6.892 ± 0.141
2.015LysPhe: 2.015 ± 0.063
4.098LysGly: 4.098 ± 0.094
1.466LysHis: 1.466 ± 0.053
6.089LysIle: 6.089 ± 0.125
7.559LysLys: 7.559 ± 0.166
6.093LysLeu: 6.093 ± 0.12
1.719LysMet: 1.719 ± 0.045
4.243LysAsn: 4.243 ± 0.095
2.564LysPro: 2.564 ± 0.079
3.865LysGln: 3.865 ± 0.089
3.323LysArg: 3.323 ± 0.087
3.964LysSer: 3.964 ± 0.082
4.445LysThr: 4.445 ± 0.109
3.764LysVal: 3.764 ± 0.087
0.968LysTrp: 0.968 ± 0.047
2.006LysTyr: 2.006 ± 0.055
0.0LysXaa: 0.0 ± 0.0
Leu
7.456LeuAla: 7.456 ± 0.144
1.853LeuCys: 1.853 ± 0.063
5.191LeuAsp: 5.191 ± 0.111
7.97LeuGlu: 7.97 ± 0.15
6.1LeuPhe: 6.1 ± 0.14
6.074LeuGly: 6.074 ± 0.124
2.753LeuHis: 2.753 ± 0.075
8.615LeuIle: 8.615 ± 0.156
8.617LeuLys: 8.617 ± 0.154
12.243LeuLeu: 12.243 ± 0.187
2.109LeuMet: 2.109 ± 0.068
4.796LeuAsn: 4.796 ± 0.106
4.594LeuPro: 4.594 ± 0.101
5.4LeuGln: 5.4 ± 0.126
4.307LeuArg: 4.307 ± 0.083
9.21LeuSer: 9.21 ± 0.158
5.226LeuThr: 5.226 ± 0.118
5.656LeuVal: 5.656 ± 0.115
1.014LeuTrp: 1.014 ± 0.053
3.411LeuTyr: 3.411 ± 0.087
0.0LeuXaa: 0.0 ± 0.0
Met
1.376MetAla: 1.376 ± 0.05
0.195MetCys: 0.195 ± 0.018
0.963MetAsp: 0.963 ± 0.04
1.098MetGlu: 1.098 ± 0.046
0.672MetPhe: 0.672 ± 0.034
1.464MetGly: 1.464 ± 0.059
0.619MetHis: 0.619 ± 0.032
1.613MetIle: 1.613 ± 0.049
1.567MetLys: 1.567 ± 0.056
2.232MetLeu: 2.232 ± 0.074
0.461MetMet: 0.461 ± 0.032
0.948MetAsn: 0.948 ± 0.044
0.869MetPro: 0.869 ± 0.041
1.409MetGln: 1.409 ± 0.052
1.117MetArg: 1.117 ± 0.051
1.572MetSer: 1.572 ± 0.056
1.188MetThr: 1.188 ± 0.049
1.043MetVal: 1.043 ± 0.05
0.165MetTrp: 0.165 ± 0.017
0.511MetTyr: 0.511 ± 0.027
0.0MetXaa: 0.0 ± 0.0
Asn
2.779AsnAla: 2.779 ± 0.066
0.615AsnCys: 0.615 ± 0.033
1.751AsnAsp: 1.751 ± 0.066
2.274AsnGlu: 2.274 ± 0.063
2.006AsnPhe: 2.006 ± 0.072
2.243AsnGly: 2.243 ± 0.104
1.233AsnHis: 1.233 ± 0.051
3.152AsnIle: 3.152 ± 0.076
2.884AsnLys: 2.884 ± 0.079
4.866AsnLeu: 4.866 ± 0.116
0.874AsnMet: 0.874 ± 0.038
1.765AsnAsn: 1.765 ± 0.063
2.557AsnPro: 2.557 ± 0.074
2.533AsnGln: 2.533 ± 0.071
2.246AsnArg: 2.246 ± 0.073
2.645AsnSer: 2.645 ± 0.071
2.333AsnThr: 2.333 ± 0.08
1.987AsnVal: 1.987 ± 0.06
0.685AsnTrp: 0.685 ± 0.039
1.673AsnTyr: 1.673 ± 0.054
0.0AsnXaa: 0.0 ± 0.0
Pro
2.089ProAla: 2.089 ± 0.061
0.58ProCys: 0.58 ± 0.036
1.872ProAsp: 1.872 ± 0.059
2.741ProGlu: 2.741 ± 0.073
2.316ProPhe: 2.316 ± 0.073
2.057ProGly: 2.057 ± 0.066
1.126ProHis: 1.126 ± 0.046
3.497ProIle: 3.497 ± 0.078
2.888ProLys: 2.888 ± 0.075
4.62ProLeu: 4.62 ± 0.094
0.755ProMet: 0.755 ± 0.039
1.874ProAsn: 1.874 ± 0.071
1.503ProPro: 1.503 ± 0.065
1.642ProGln: 1.642 ± 0.056
1.431ProArg: 1.431 ± 0.055
3.295ProSer: 3.295 ± 0.076
1.991ProThr: 1.991 ± 0.069
2.224ProVal: 2.224 ± 0.063
0.415ProTrp: 0.415 ± 0.028
1.477ProTyr: 1.477 ± 0.047
0.0ProXaa: 0.0 ± 0.0
Gln
3.589GlnAla: 3.589 ± 0.096
0.384GlnCys: 0.384 ± 0.03
1.975GlnAsp: 1.975 ± 0.07
4.217GlnGlu: 4.217 ± 0.107
1.826GlnPhe: 1.826 ± 0.058
2.518GlnGly: 2.518 ± 0.083
0.801GlnHis: 0.801 ± 0.046
3.808GlnIle: 3.808 ± 0.103
4.342GlnLys: 4.342 ± 0.098
4.868GlnLeu: 4.868 ± 0.106
1.115GlnMet: 1.115 ± 0.043
2.048GlnAsn: 2.048 ± 0.087
1.304GlnPro: 1.304 ± 0.053
2.145GlnGln: 2.145 ± 0.073
1.872GlnArg: 1.872 ± 0.05
2.539GlnSer: 2.539 ± 0.065
2.327GlnThr: 2.327 ± 0.071
2.568GlnVal: 2.568 ± 0.061
0.492GlnTrp: 0.492 ± 0.03
1.214GlnTyr: 1.214 ± 0.041
0.0GlnXaa: 0.0 ± 0.0
Arg
2.498ArgAla: 2.498 ± 0.061
0.544ArgCys: 0.544 ± 0.033
1.818ArgAsp: 1.818 ± 0.063
2.726ArgGlu: 2.726 ± 0.071
2.461ArgPhe: 2.461 ± 0.069
2.046ArgGly: 2.046 ± 0.075
0.99ArgHis: 0.99 ± 0.044
3.33ArgIle: 3.33 ± 0.087
2.985ArgLys: 2.985 ± 0.078
4.906ArgLeu: 4.906 ± 0.101
1.047ArgMet: 1.047 ± 0.043
1.886ArgAsn: 1.886 ± 0.059
1.389ArgPro: 1.389 ± 0.057
1.699ArgGln: 1.699 ± 0.059
1.958ArgArg: 1.958 ± 0.072
2.928ArgSer: 2.928 ± 0.077
1.743ArgThr: 1.743 ± 0.061
2.401ArgVal: 2.401 ± 0.075
0.47ArgTrp: 0.47 ± 0.032
1.664ArgTyr: 1.664 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
4.146SerAla: 4.146 ± 0.097
1.24SerCys: 1.24 ± 0.045
2.989SerAsp: 2.989 ± 0.081
3.764SerGlu: 3.764 ± 0.095
4.383SerPhe: 4.383 ± 0.099
3.811SerGly: 3.811 ± 0.135
1.782SerHis: 1.782 ± 0.057
5.489SerIle: 5.489 ± 0.107
4.324SerLys: 4.324 ± 0.095
9.146SerLeu: 9.146 ± 0.151
1.602SerMet: 1.602 ± 0.054
2.742SerAsn: 2.742 ± 0.079
2.715SerPro: 2.715 ± 0.065
3.034SerGln: 3.034 ± 0.074
2.685SerArg: 2.685 ± 0.078
6.33SerSer: 6.33 ± 0.134
3.26SerThr: 3.26 ± 0.085
3.457SerVal: 3.457 ± 0.088
0.898SerTrp: 0.898 ± 0.044
2.939SerTyr: 2.939 ± 0.081
0.0SerXaa: 0.0 ± 0.0
Thr
3.468ThrAla: 3.468 ± 0.098
0.715ThrCys: 0.715 ± 0.032
2.096ThrAsp: 2.096 ± 0.069
2.851ThrGlu: 2.851 ± 0.08
2.232ThrPhe: 2.232 ± 0.058
3.176ThrGly: 3.176 ± 0.113
1.35ThrHis: 1.35 ± 0.056
3.973ThrIle: 3.973 ± 0.091
3.136ThrLys: 3.136 ± 0.076
5.928ThrLeu: 5.928 ± 0.111
0.885ThrMet: 0.885 ± 0.041
2.019ThrAsn: 2.019 ± 0.067
2.529ThrPro: 2.529 ± 0.085
2.188ThrGln: 2.188 ± 0.068
1.907ThrArg: 1.907 ± 0.07
3.62ThrSer: 3.62 ± 0.089
2.805ThrThr: 2.805 ± 0.086
2.674ThrVal: 2.674 ± 0.068
0.582ThrTrp: 0.582 ± 0.035
1.868ThrTyr: 1.868 ± 0.087
0.0ThrXaa: 0.0 ± 0.0
Val
3.692ValAla: 3.692 ± 0.09
0.884ValCys: 0.884 ± 0.043
2.651ValAsp: 2.651 ± 0.075
3.371ValGlu: 3.371 ± 0.099
3.147ValPhe: 3.147 ± 0.081
3.014ValGly: 3.014 ± 0.091
1.225ValHis: 1.225 ± 0.046
4.662ValIle: 4.662 ± 0.113
3.626ValLys: 3.626 ± 0.09
6.051ValLeu: 6.051 ± 0.11
1.078ValMet: 1.078 ± 0.046
2.213ValAsn: 2.213 ± 0.066
2.013ValPro: 2.013 ± 0.064
2.013ValGln: 2.013 ± 0.061
2.039ValArg: 2.039 ± 0.071
3.789ValSer: 3.789 ± 0.085
2.539ValThr: 2.539 ± 0.076
3.319ValVal: 3.319 ± 0.095
0.501ValTrp: 0.501 ± 0.029
1.699ValTyr: 1.699 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
0.61TrpAla: 0.61 ± 0.034
0.145TrpCys: 0.145 ± 0.014
0.601TrpAsp: 0.601 ± 0.038
0.896TrpGlu: 0.896 ± 0.039
0.463TrpPhe: 0.463 ± 0.031
0.696TrpGly: 0.696 ± 0.036
0.285TrpHis: 0.285 ± 0.028
1.018TrpIle: 1.018 ± 0.053
0.902TrpLys: 0.902 ± 0.044
1.238TrpLeu: 1.238 ± 0.05
0.351TrpMet: 0.351 ± 0.026
0.584TrpAsn: 0.584 ± 0.036
0.343TrpPro: 0.343 ± 0.023
0.584TrpGln: 0.584 ± 0.038
0.468TrpArg: 0.468 ± 0.031
0.582TrpSer: 0.582 ± 0.036
0.481TrpThr: 0.481 ± 0.026
0.74TrpVal: 0.74 ± 0.04
0.134TrpTrp: 0.134 ± 0.016
0.331TrpTyr: 0.331 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.408TyrAla: 2.408 ± 0.083
0.505TyrCys: 0.505 ± 0.03
1.736TyrAsp: 1.736 ± 0.107
2.019TyrGlu: 2.019 ± 0.07
1.907TyrPhe: 1.907 ± 0.064
1.738TyrGly: 1.738 ± 0.069
0.909TyrHis: 0.909 ± 0.037
2.125TyrIle: 2.125 ± 0.062
1.938TyrLys: 1.938 ± 0.056
4.408TyrLeu: 4.408 ± 0.098
0.591TyrMet: 0.591 ± 0.032
1.249TyrAsn: 1.249 ± 0.061
1.622TyrPro: 1.622 ± 0.051
2.046TyrGln: 2.046 ± 0.071
1.708TyrArg: 1.708 ± 0.061
2.197TyrSer: 2.197 ± 0.063
1.771TyrThr: 1.771 ± 0.068
1.593TyrVal: 1.593 ± 0.053
0.399TyrTrp: 0.399 ± 0.028
1.187TyrTyr: 1.187 ± 0.052
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1685 proteins (544409 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski