Amino acid dipepetide frequency for Alcelaphine herpesvirus 1 (strain C500) (AlHV-1) (Malignant catarrhal fever virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.173AlaAla: 5.173 ± 0.369
1.724AlaCys: 1.724 ± 0.226
2.759AlaAsp: 2.759 ± 0.316
3.075AlaGlu: 3.075 ± 0.295
3.104AlaPhe: 3.104 ± 0.325
2.788AlaGly: 2.788 ± 0.377
1.667AlaHis: 1.667 ± 0.223
2.989AlaIle: 2.989 ± 0.354
3.161AlaLys: 3.161 ± 0.291
7.012AlaLeu: 7.012 ± 0.53
1.494AlaMet: 1.494 ± 0.189
2.989AlaAsn: 2.989 ± 0.284
3.563AlaPro: 3.563 ± 0.436
2.558AlaGln: 2.558 ± 0.323
2.27AlaArg: 2.27 ± 0.255
5.747AlaSer: 5.747 ± 0.473
4.311AlaThr: 4.311 ± 0.284
4.224AlaVal: 4.224 ± 0.398
0.603AlaTrp: 0.603 ± 0.135
1.925AlaTyr: 1.925 ± 0.254
0.0AlaXaa: 0.0 ± 0.0
Cys
1.868CysAla: 1.868 ± 0.298
0.776CysCys: 0.776 ± 0.186
0.862CysAsp: 0.862 ± 0.136
1.149CysGlu: 1.149 ± 0.214
1.264CysPhe: 1.264 ± 0.206
1.581CysGly: 1.581 ± 0.259
0.661CysHis: 0.661 ± 0.119
1.523CysIle: 1.523 ± 0.214
1.236CysLys: 1.236 ± 0.163
3.046CysLeu: 3.046 ± 0.449
0.603CysMet: 0.603 ± 0.137
1.149CysAsn: 1.149 ± 0.182
1.322CysPro: 1.322 ± 0.214
1.322CysGln: 1.322 ± 0.159
0.891CysArg: 0.891 ± 0.143
2.04CysSer: 2.04 ± 0.289
1.868CysThr: 1.868 ± 0.221
1.695CysVal: 1.695 ± 0.254
0.23CysTrp: 0.23 ± 0.078
1.149CysTyr: 1.149 ± 0.174
0.0CysXaa: 0.0 ± 0.0
Asp
2.73AspAla: 2.73 ± 0.357
0.948AspCys: 0.948 ± 0.167
2.385AspAsp: 2.385 ± 0.436
2.96AspGlu: 2.96 ± 0.478
2.529AspPhe: 2.529 ± 0.235
2.5AspGly: 2.5 ± 0.558
1.006AspHis: 1.006 ± 0.193
3.535AspIle: 3.535 ± 0.255
1.983AspLys: 1.983 ± 0.272
4.081AspLeu: 4.081 ± 0.364
1.121AspMet: 1.121 ± 0.163
1.581AspAsn: 1.581 ± 0.252
2.902AspPro: 2.902 ± 0.323
1.466AspGln: 1.466 ± 0.257
1.782AspArg: 1.782 ± 0.223
4.483AspSer: 4.483 ± 0.497
2.759AspThr: 2.759 ± 0.272
3.19AspVal: 3.19 ± 0.231
0.603AspTrp: 0.603 ± 0.127
1.925AspTyr: 1.925 ± 0.25
0.0AspXaa: 0.0 ± 0.0
Glu
3.563GluAla: 3.563 ± 0.401
1.724GluCys: 1.724 ± 0.259
3.219GluAsp: 3.219 ± 0.502
5.201GluGlu: 5.201 ± 1.334
1.925GluPhe: 1.925 ± 0.27
7.529GluGly: 7.529 ± 5.121
0.92GluHis: 0.92 ± 0.17
2.615GluIle: 2.615 ± 0.282
2.73GluLys: 2.73 ± 0.461
4.77GluLeu: 4.77 ± 0.478
1.322GluMet: 1.322 ± 0.199
2.902GluAsn: 2.902 ± 0.265
2.443GluPro: 2.443 ± 0.259
2.012GluGln: 2.012 ± 0.259
2.213GluArg: 2.213 ± 0.257
3.736GluSer: 3.736 ± 0.33
3.334GluThr: 3.334 ± 0.378
3.707GluVal: 3.707 ± 0.318
0.632GluTrp: 0.632 ± 0.123
1.782GluTyr: 1.782 ± 0.238
0.0GluXaa: 0.0 ± 0.0
Phe
2.242PheAla: 2.242 ± 0.239
1.236PheCys: 1.236 ± 0.233
2.098PheAsp: 2.098 ± 0.179
2.414PheGlu: 2.414 ± 0.283
3.104PhePhe: 3.104 ± 0.306
1.925PheGly: 1.925 ± 0.338
0.948PheHis: 0.948 ± 0.156
2.874PheIle: 2.874 ± 0.286
3.19PheLys: 3.19 ± 0.349
4.943PheLeu: 4.943 ± 0.57
1.178PheMet: 1.178 ± 0.173
2.299PheAsn: 2.299 ± 0.235
2.385PhePro: 2.385 ± 0.225
1.753PheGln: 1.753 ± 0.238
1.724PheArg: 1.724 ± 0.213
4.081PheSer: 4.081 ± 0.421
3.19PheThr: 3.19 ± 0.324
3.132PheVal: 3.132 ± 0.308
0.575PheTrp: 0.575 ± 0.119
2.644PheTyr: 2.644 ± 0.229
0.0PheXaa: 0.0 ± 0.0
Gly
3.477GlyAla: 3.477 ± 0.348
1.207GlyCys: 1.207 ± 0.233
2.989GlyAsp: 2.989 ± 0.334
4.684GlyGlu: 4.684 ± 2.148
2.356GlyPhe: 2.356 ± 0.324
4.914GlyGly: 4.914 ± 1.882
0.977GlyHis: 0.977 ± 0.175
2.471GlyIle: 2.471 ± 0.258
2.299GlyLys: 2.299 ± 0.247
5.431GlyLeu: 5.431 ± 0.364
0.747GlyMet: 0.747 ± 0.109
2.155GlyAsn: 2.155 ± 0.245
6.782GlyPro: 6.782 ± 3.678
2.385GlyGln: 2.385 ± 0.269
2.127GlyArg: 2.127 ± 0.243
4.742GlySer: 4.742 ± 0.576
2.701GlyThr: 2.701 ± 0.272
2.989GlyVal: 2.989 ± 0.346
0.431GlyTrp: 0.431 ± 0.145
1.552GlyTyr: 1.552 ± 0.217
0.0GlyXaa: 0.0 ± 0.0
His
1.782HisAla: 1.782 ± 0.244
0.546HisCys: 0.546 ± 0.127
0.661HisAsp: 0.661 ± 0.125
1.092HisGlu: 1.092 ± 0.192
1.092HisPhe: 1.092 ± 0.175
1.494HisGly: 1.494 ± 0.197
0.661HisHis: 0.661 ± 0.146
1.494HisIle: 1.494 ± 0.257
1.236HisLys: 1.236 ± 0.203
2.673HisLeu: 2.673 ± 0.302
0.546HisMet: 0.546 ± 0.134
1.236HisAsn: 1.236 ± 0.204
1.609HisPro: 1.609 ± 0.206
1.264HisGln: 1.264 ± 0.225
1.149HisArg: 1.149 ± 0.16
2.012HisSer: 2.012 ± 0.235
1.782HisThr: 1.782 ± 0.233
1.351HisVal: 1.351 ± 0.186
0.374HisTrp: 0.374 ± 0.091
0.833HisTyr: 0.833 ± 0.153
0.0HisXaa: 0.0 ± 0.0
Ile
2.845IleAla: 2.845 ± 0.319
1.466IleCys: 1.466 ± 0.192
2.27IleAsp: 2.27 ± 0.256
2.443IleGlu: 2.443 ± 0.32
2.874IlePhe: 2.874 ± 0.318
1.782IleGly: 1.782 ± 0.258
1.379IleHis: 1.379 ± 0.18
3.276IleIle: 3.276 ± 0.312
3.362IleLys: 3.362 ± 0.345
5.316IleLeu: 5.316 ± 0.45
1.006IleMet: 1.006 ± 0.184
3.276IleAsn: 3.276 ± 0.301
2.874IlePro: 2.874 ± 0.292
2.213IleGln: 2.213 ± 0.342
1.466IleArg: 1.466 ± 0.221
4.167IleSer: 4.167 ± 0.4
3.678IleThr: 3.678 ± 0.313
2.788IleVal: 2.788 ± 0.3
0.69IleTrp: 0.69 ± 0.146
2.615IleTyr: 2.615 ± 0.335
0.0IleXaa: 0.0 ± 0.0
Lys
2.989LysAla: 2.989 ± 0.289
1.466LysCys: 1.466 ± 0.229
2.759LysAsp: 2.759 ± 0.321
2.586LysGlu: 2.586 ± 0.297
2.04LysPhe: 2.04 ± 0.226
2.443LysGly: 2.443 ± 0.325
1.494LysHis: 1.494 ± 0.194
3.19LysIle: 3.19 ± 0.296
3.994LysLys: 3.994 ± 0.39
5.518LysLeu: 5.518 ± 0.458
1.149LysMet: 1.149 ± 0.16
2.902LysAsn: 2.902 ± 0.244
2.931LysPro: 2.931 ± 0.362
2.558LysGln: 2.558 ± 0.262
2.328LysArg: 2.328 ± 0.285
3.42LysSer: 3.42 ± 0.349
3.592LysThr: 3.592 ± 0.36
3.391LysVal: 3.391 ± 0.301
0.546LysTrp: 0.546 ± 0.129
1.667LysTyr: 1.667 ± 0.207
0.0LysXaa: 0.0 ± 0.0
Leu
6.293LeuAla: 6.293 ± 0.383
2.558LeuCys: 2.558 ± 0.314
4.512LeuAsp: 4.512 ± 0.338
5.776LeuGlu: 5.776 ± 0.395
5.403LeuPhe: 5.403 ± 0.492
5.345LeuGly: 5.345 ± 0.399
2.673LeuHis: 2.673 ± 0.235
4.512LeuIle: 4.512 ± 0.389
5.69LeuLys: 5.69 ± 0.422
11.61LeuLeu: 11.61 ± 0.689
2.213LeuMet: 2.213 ± 0.231
5.201LeuAsn: 5.201 ± 0.503
5.575LeuPro: 5.575 ± 0.489
5.058LeuGln: 5.058 ± 0.432
4.627LeuArg: 4.627 ± 0.383
9.311LeuSer: 9.311 ± 0.629
6.638LeuThr: 6.638 ± 0.439
5.403LeuVal: 5.403 ± 0.443
1.035LeuTrp: 1.035 ± 0.197
3.678LeuTyr: 3.678 ± 0.327
0.0LeuXaa: 0.0 ± 0.0
Met
2.127MetAla: 2.127 ± 0.227
0.69MetCys: 0.69 ± 0.122
1.236MetAsp: 1.236 ± 0.137
1.207MetGlu: 1.207 ± 0.199
1.178MetPhe: 1.178 ± 0.205
1.035MetGly: 1.035 ± 0.185
0.431MetHis: 0.431 ± 0.085
1.121MetIle: 1.121 ± 0.19
1.006MetLys: 1.006 ± 0.154
2.673MetLeu: 2.673 ± 0.24
0.489MetMet: 0.489 ± 0.143
0.69MetAsn: 0.69 ± 0.153
0.862MetPro: 0.862 ± 0.129
0.805MetGln: 0.805 ± 0.164
0.862MetArg: 0.862 ± 0.144
1.494MetSer: 1.494 ± 0.157
0.977MetThr: 0.977 ± 0.183
1.035MetVal: 1.035 ± 0.192
0.374MetTrp: 0.374 ± 0.107
0.891MetTyr: 0.891 ± 0.167
0.0MetXaa: 0.0 ± 0.0
Asn
2.701AsnAla: 2.701 ± 0.286
1.379AsnCys: 1.379 ± 0.222
1.667AsnAsp: 1.667 ± 0.229
1.983AsnGlu: 1.983 ± 0.216
2.845AsnPhe: 2.845 ± 0.337
2.328AsnGly: 2.328 ± 0.262
1.207AsnHis: 1.207 ± 0.184
3.448AsnIle: 3.448 ± 0.328
2.586AsnLys: 2.586 ± 0.304
5.661AsnLeu: 5.661 ± 0.486
1.264AsnMet: 1.264 ± 0.216
3.075AsnAsn: 3.075 ± 0.296
2.73AsnPro: 2.73 ± 0.26
1.868AsnGln: 1.868 ± 0.231
1.638AsnArg: 1.638 ± 0.242
4.454AsnSer: 4.454 ± 0.443
3.276AsnThr: 3.276 ± 0.308
3.104AsnVal: 3.104 ± 0.298
0.46AsnTrp: 0.46 ± 0.105
1.523AsnTyr: 1.523 ± 0.181
0.0AsnXaa: 0.0 ± 0.0
Pro
3.592ProAla: 3.592 ± 0.375
1.466ProCys: 1.466 ± 0.217
2.673ProAsp: 2.673 ± 0.549
6.121ProGlu: 6.121 ± 2.503
2.098ProPhe: 2.098 ± 0.228
4.54ProGly: 4.54 ± 0.805
1.379ProHis: 1.379 ± 0.212
2.845ProIle: 2.845 ± 0.345
2.902ProLys: 2.902 ± 0.47
4.598ProLeu: 4.598 ± 0.321
0.92ProMet: 0.92 ± 0.119
2.242ProAsn: 2.242 ± 0.235
4.54ProPro: 4.54 ± 0.652
2.73ProGln: 2.73 ± 0.355
2.558ProArg: 2.558 ± 0.374
4.569ProSer: 4.569 ± 0.343
3.621ProThr: 3.621 ± 0.391
4.512ProVal: 4.512 ± 0.428
0.603ProTrp: 0.603 ± 0.127
1.236ProTyr: 1.236 ± 0.209
0.0ProXaa: 0.0 ± 0.0
Gln
2.96GlnAla: 2.96 ± 0.478
1.092GlnCys: 1.092 ± 0.17
1.954GlnAsp: 1.954 ± 0.244
2.356GlnGlu: 2.356 ± 0.344
2.04GlnPhe: 2.04 ± 0.285
2.328GlnGly: 2.328 ± 0.213
1.293GlnHis: 1.293 ± 0.191
1.782GlnIle: 1.782 ± 0.231
2.5GlnLys: 2.5 ± 0.31
4.828GlnLeu: 4.828 ± 0.494
0.718GlnMet: 0.718 ± 0.121
2.529GlnAsn: 2.529 ± 0.235
2.155GlnPro: 2.155 ± 0.278
2.73GlnGln: 2.73 ± 0.32
1.494GlnArg: 1.494 ± 0.245
3.075GlnSer: 3.075 ± 0.331
2.385GlnThr: 2.385 ± 0.281
2.471GlnVal: 2.471 ± 0.269
0.46GlnTrp: 0.46 ± 0.121
1.351GlnTyr: 1.351 ± 0.226
0.0GlnXaa: 0.0 ± 0.0
Arg
3.075ArgAla: 3.075 ± 0.346
1.178ArgCys: 1.178 ± 0.182
2.098ArgAsp: 2.098 ± 0.228
2.443ArgGlu: 2.443 ± 0.298
1.437ArgPhe: 1.437 ± 0.195
2.328ArgGly: 2.328 ± 0.355
1.638ArgHis: 1.638 ± 0.254
1.494ArgIle: 1.494 ± 0.198
1.839ArgLys: 1.839 ± 0.272
3.793ArgLeu: 3.793 ± 0.353
0.862ArgMet: 0.862 ± 0.183
1.379ArgAsn: 1.379 ± 0.229
2.385ArgPro: 2.385 ± 0.298
1.983ArgGln: 1.983 ± 0.242
2.615ArgArg: 2.615 ± 0.407
2.989ArgSer: 2.989 ± 0.241
1.466ArgThr: 1.466 ± 0.203
2.529ArgVal: 2.529 ± 0.24
0.517ArgTrp: 0.517 ± 0.127
1.236ArgTyr: 1.236 ± 0.174
0.0ArgXaa: 0.0 ± 0.0
Ser
4.684SerAla: 4.684 ± 0.364
2.127SerCys: 2.127 ± 0.286
4.253SerAsp: 4.253 ± 0.415
3.765SerGlu: 3.765 ± 0.319
3.822SerPhe: 3.822 ± 0.34
4.713SerGly: 4.713 ± 0.472
2.127SerHis: 2.127 ± 0.252
3.966SerIle: 3.966 ± 0.345
4.138SerLys: 4.138 ± 0.351
8.506SerLeu: 8.506 ± 0.747
1.839SerMet: 1.839 ± 0.192
4.311SerAsn: 4.311 ± 0.372
5.144SerPro: 5.144 ± 0.432
3.219SerGln: 3.219 ± 0.294
3.477SerArg: 3.477 ± 0.303
8.42SerSer: 8.42 ± 0.636
6.064SerThr: 6.064 ± 0.533
5.144SerVal: 5.144 ± 0.366
0.948SerTrp: 0.948 ± 0.168
2.5SerTyr: 2.5 ± 0.272
0.0SerXaa: 0.0 ± 0.0
Thr
4.138ThrAla: 4.138 ± 0.335
1.466ThrCys: 1.466 ± 0.225
2.96ThrAsp: 2.96 ± 0.334
3.793ThrGlu: 3.793 ± 0.34
3.161ThrPhe: 3.161 ± 0.337
2.615ThrGly: 2.615 ± 0.317
1.839ThrHis: 1.839 ± 0.214
2.931ThrIle: 2.931 ± 0.31
2.931ThrLys: 2.931 ± 0.279
6.466ThrLeu: 6.466 ± 0.463
1.236ThrMet: 1.236 ± 0.181
2.874ThrAsn: 2.874 ± 0.25
4.052ThrPro: 4.052 ± 0.456
2.471ThrGln: 2.471 ± 0.32
1.954ThrArg: 1.954 ± 0.282
5.46ThrSer: 5.46 ± 0.425
4.311ThrThr: 4.311 ± 0.539
5.288ThrVal: 5.288 ± 0.455
0.661ThrTrp: 0.661 ± 0.13
2.299ThrTyr: 2.299 ± 0.279
0.0ThrXaa: 0.0 ± 0.0
Val
4.339ValAla: 4.339 ± 0.419
2.098ValCys: 2.098 ± 0.221
2.989ValAsp: 2.989 ± 0.28
3.161ValGlu: 3.161 ± 0.281
3.276ValPhe: 3.276 ± 0.299
2.96ValGly: 2.96 ± 0.334
1.581ValHis: 1.581 ± 0.241
3.219ValIle: 3.219 ± 0.29
3.707ValLys: 3.707 ± 0.321
6.495ValLeu: 6.495 ± 0.429
1.523ValMet: 1.523 ± 0.196
3.793ValAsn: 3.793 ± 0.363
3.362ValPro: 3.362 ± 0.252
2.5ValGln: 2.5 ± 0.258
2.414ValArg: 2.414 ± 0.239
5.719ValSer: 5.719 ± 0.465
3.621ValThr: 3.621 ± 0.303
4.426ValVal: 4.426 ± 0.41
0.46ValTrp: 0.46 ± 0.134
2.586ValTyr: 2.586 ± 0.423
0.0ValXaa: 0.0 ± 0.0
Trp
0.747TrpAla: 0.747 ± 0.138
0.144TrpCys: 0.144 ± 0.073
0.546TrpAsp: 0.546 ± 0.133
0.517TrpGlu: 0.517 ± 0.129
0.374TrpPhe: 0.374 ± 0.115
0.603TrpGly: 0.603 ± 0.149
0.259TrpHis: 0.259 ± 0.089
0.431TrpIle: 0.431 ± 0.105
0.489TrpLys: 0.489 ± 0.105
1.408TrpLeu: 1.408 ± 0.2
0.201TrpMet: 0.201 ± 0.086
0.546TrpAsn: 0.546 ± 0.105
0.69TrpPro: 0.69 ± 0.13
0.489TrpGln: 0.489 ± 0.139
0.402TrpArg: 0.402 ± 0.103
0.747TrpSer: 0.747 ± 0.155
0.805TrpThr: 0.805 ± 0.153
0.805TrpVal: 0.805 ± 0.131
0.086TrpTrp: 0.086 ± 0.046
0.316TrpTyr: 0.316 ± 0.118
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.81TyrAla: 1.81 ± 0.235
0.948TyrCys: 0.948 ± 0.2
1.581TyrAsp: 1.581 ± 0.207
1.552TyrGlu: 1.552 ± 0.186
2.012TyrPhe: 2.012 ± 0.238
1.667TyrGly: 1.667 ± 0.274
0.747TyrHis: 0.747 ± 0.168
2.069TyrIle: 2.069 ± 0.239
1.983TyrLys: 1.983 ± 0.235
4.282TyrLeu: 4.282 ± 0.393
0.747TyrMet: 0.747 ± 0.133
2.069TyrAsn: 2.069 ± 0.312
1.437TyrPro: 1.437 ± 0.198
1.121TyrGln: 1.121 ± 0.162
1.293TyrArg: 1.293 ± 0.186
2.5TyrSer: 2.5 ± 0.278
2.529TyrThr: 2.529 ± 0.281
3.046TyrVal: 3.046 ± 0.295
0.316TyrTrp: 0.316 ± 0.091
1.264TyrTyr: 1.264 ± 0.261
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 70 proteins (34799 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski