Amino acid dipepetide frequency for Quaranfil virus (isolate QrfV/Tick/Afghanistan/EG_T_377/1968) (QRFV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.141AlaAla: 5.141 ± 1.133
1.143AlaCys: 1.143 ± 0.734
2.856AlaAsp: 2.856 ± 0.431
3.142AlaGlu: 3.142 ± 0.765
3.428AlaPhe: 3.428 ± 1.211
4.284AlaGly: 4.284 ± 1.636
0.571AlaHis: 0.571 ± 0.332
3.428AlaIle: 3.428 ± 0.885
3.428AlaLys: 3.428 ± 0.762
8.283AlaLeu: 8.283 ± 1.023
0.857AlaMet: 0.857 ± 0.489
2.856AlaAsn: 2.856 ± 0.632
2.285AlaPro: 2.285 ± 1.054
4.57AlaGln: 4.57 ± 0.667
2.856AlaArg: 2.856 ± 1.386
3.713AlaSer: 3.713 ± 0.579
5.713AlaThr: 5.713 ± 1.147
2.571AlaVal: 2.571 ± 0.874
0.857AlaTrp: 0.857 ± 0.565
1.714AlaTyr: 1.714 ± 0.301
0.0AlaXaa: 0.0 ± 0.0
Cys
0.857CysAla: 0.857 ± 0.405
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.286CysGlu: 0.286 ± 0.232
1.143CysPhe: 1.143 ± 0.664
0.571CysGly: 0.571 ± 0.332
0.857CysHis: 0.857 ± 0.405
0.571CysIle: 0.571 ± 0.358
0.857CysLys: 0.857 ± 0.343
1.428CysLeu: 1.428 ± 0.439
0.286CysMet: 0.286 ± 0.232
1.428CysAsn: 1.428 ± 0.54
0.857CysPro: 0.857 ± 0.315
0.571CysGln: 0.571 ± 0.358
0.571CysArg: 0.571 ± 0.272
2.571CysSer: 2.571 ± 0.382
1.428CysThr: 1.428 ± 0.788
0.571CysVal: 0.571 ± 0.417
0.286CysTrp: 0.286 ± 0.277
0.571CysTyr: 0.571 ± 0.553
0.0CysXaa: 0.0 ± 0.0
Asp
1.143AspAla: 1.143 ± 0.503
1.428AspCys: 1.428 ± 0.453
3.142AspAsp: 3.142 ± 0.901
1.999AspGlu: 1.999 ± 0.598
3.428AspPhe: 3.428 ± 1.526
4.57AspGly: 4.57 ± 1.174
0.571AspHis: 0.571 ± 0.303
1.999AspIle: 1.999 ± 0.51
3.428AspLys: 3.428 ± 1.018
4.856AspLeu: 4.856 ± 1.379
0.857AspMet: 0.857 ± 0.437
2.571AspAsn: 2.571 ± 0.913
3.142AspPro: 3.142 ± 1.003
1.999AspGln: 1.999 ± 0.76
2.571AspArg: 2.571 ± 0.937
4.856AspSer: 4.856 ± 1.14
2.285AspThr: 2.285 ± 0.91
2.856AspVal: 2.856 ± 0.462
2.285AspTrp: 2.285 ± 0.925
1.143AspTyr: 1.143 ± 0.61
0.0AspXaa: 0.0 ± 0.0
Glu
4.284GluAla: 4.284 ± 1.035
0.857GluCys: 0.857 ± 0.405
3.713GluAsp: 3.713 ± 0.251
10.283GluGlu: 10.283 ± 2.036
1.714GluPhe: 1.714 ± 0.417
6.57GluGly: 6.57 ± 2.125
1.999GluHis: 1.999 ± 0.656
4.284GluIle: 4.284 ± 1.243
6.855GluLys: 6.855 ± 0.796
5.141GluLeu: 5.141 ± 1.137
3.428GluMet: 3.428 ± 1.091
2.856GluAsn: 2.856 ± 0.805
2.285GluPro: 2.285 ± 1.315
0.571GluGln: 0.571 ± 0.314
3.999GluArg: 3.999 ± 0.953
3.999GluSer: 3.999 ± 1.032
4.284GluThr: 4.284 ± 1.191
5.141GluVal: 5.141 ± 1.372
0.857GluTrp: 0.857 ± 0.32
1.428GluTyr: 1.428 ± 0.558
0.0GluXaa: 0.0 ± 0.0
Phe
1.714PheAla: 1.714 ± 0.548
0.857PheCys: 0.857 ± 0.486
1.714PheAsp: 1.714 ± 0.802
2.856PheGlu: 2.856 ± 0.811
0.571PhePhe: 0.571 ± 0.316
3.999PheGly: 3.999 ± 0.986
2.285PheHis: 2.285 ± 0.801
0.857PheIle: 0.857 ± 0.317
2.285PheLys: 2.285 ± 0.851
3.142PheLeu: 3.142 ± 0.895
1.428PheMet: 1.428 ± 0.47
3.142PheAsn: 3.142 ± 0.61
1.714PhePro: 1.714 ± 0.49
1.999PheGln: 1.999 ± 0.493
2.285PheArg: 2.285 ± 0.501
4.284PheSer: 4.284 ± 0.711
2.285PheThr: 2.285 ± 0.571
1.714PheVal: 1.714 ± 0.698
0.286PheTrp: 0.286 ± 0.254
1.143PheTyr: 1.143 ± 0.477
0.0PheXaa: 0.0 ± 0.0
Gly
5.141GlyAla: 5.141 ± 0.762
0.286GlyCys: 0.286 ± 0.277
3.999GlyAsp: 3.999 ± 1.233
3.999GlyGlu: 3.999 ± 1.195
1.714GlyPhe: 1.714 ± 0.414
6.855GlyGly: 6.855 ± 1.701
0.857GlyHis: 0.857 ± 0.267
3.142GlyIle: 3.142 ± 0.439
4.856GlyLys: 4.856 ± 1.367
5.427GlyLeu: 5.427 ± 0.952
2.285GlyMet: 2.285 ± 0.846
3.713GlyAsn: 3.713 ± 1.58
3.999GlyPro: 3.999 ± 0.546
0.857GlyGln: 0.857 ± 0.344
2.571GlyArg: 2.571 ± 0.857
5.141GlySer: 5.141 ± 1.344
3.999GlyThr: 3.999 ± 1.36
6.284GlyVal: 6.284 ± 1.126
1.714GlyTrp: 1.714 ± 0.414
2.285GlyTyr: 2.285 ± 0.701
0.0GlyXaa: 0.0 ± 0.0
His
1.714HisAla: 1.714 ± 0.53
0.286HisCys: 0.286 ± 0.254
2.571HisAsp: 2.571 ± 0.688
1.143HisGlu: 1.143 ± 0.705
2.571HisPhe: 2.571 ± 0.643
0.571HisGly: 0.571 ± 0.358
1.714HisHis: 1.714 ± 0.268
0.571HisIle: 0.571 ± 0.55
1.714HisLys: 1.714 ± 0.423
3.428HisLeu: 3.428 ± 1.189
0.286HisMet: 0.286 ± 0.277
1.428HisAsn: 1.428 ± 0.38
0.286HisPro: 0.286 ± 0.254
0.286HisGln: 0.286 ± 0.277
0.571HisArg: 0.571 ± 0.303
1.428HisSer: 1.428 ± 0.522
1.999HisThr: 1.999 ± 0.64
1.714HisVal: 1.714 ± 0.791
0.286HisTrp: 0.286 ± 0.232
0.571HisTyr: 0.571 ± 0.508
0.0HisXaa: 0.0 ± 0.0
Ile
3.142IleAla: 3.142 ± 1.153
0.0IleCys: 0.0 ± 0.0
3.999IleAsp: 3.999 ± 1.072
3.713IleGlu: 3.713 ± 0.862
1.714IlePhe: 1.714 ± 0.384
3.428IleGly: 3.428 ± 0.833
1.999IleHis: 1.999 ± 0.383
2.571IleIle: 2.571 ± 0.755
1.999IleLys: 1.999 ± 1.156
3.713IleLeu: 3.713 ± 0.606
1.714IleMet: 1.714 ± 0.485
3.142IleAsn: 3.142 ± 0.843
1.428IlePro: 1.428 ± 0.558
1.143IleGln: 1.143 ± 0.483
2.856IleArg: 2.856 ± 0.893
3.142IleSer: 3.142 ± 0.832
3.428IleThr: 3.428 ± 1.016
1.714IleVal: 1.714 ± 0.583
1.143IleTrp: 1.143 ± 0.274
1.143IleTyr: 1.143 ± 0.374
0.0IleXaa: 0.0 ± 0.0
Lys
2.856LysAla: 2.856 ± 0.58
1.714LysCys: 1.714 ± 0.833
2.856LysAsp: 2.856 ± 1.235
5.998LysGlu: 5.998 ± 1.67
2.856LysPhe: 2.856 ± 1.114
3.713LysGly: 3.713 ± 0.966
0.571LysHis: 0.571 ± 0.272
4.856LysIle: 4.856 ± 1.175
2.571LysLys: 2.571 ± 0.751
3.999LysLeu: 3.999 ± 0.543
2.856LysMet: 2.856 ± 0.676
1.143LysAsn: 1.143 ± 0.704
1.999LysPro: 1.999 ± 0.646
2.285LysGln: 2.285 ± 0.679
7.426LysArg: 7.426 ± 1.591
3.999LysSer: 3.999 ± 0.603
4.856LysThr: 4.856 ± 1.214
5.427LysVal: 5.427 ± 1.176
3.428LysTrp: 3.428 ± 1.082
1.714LysTyr: 1.714 ± 0.735
0.0LysXaa: 0.0 ± 0.0
Leu
6.855LeuAla: 6.855 ± 0.577
0.286LeuCys: 0.286 ± 0.232
4.57LeuAsp: 4.57 ± 1.081
7.141LeuGlu: 7.141 ± 1.318
2.856LeuPhe: 2.856 ± 0.757
5.713LeuGly: 5.713 ± 0.663
3.142LeuHis: 3.142 ± 1.008
3.713LeuIle: 3.713 ± 0.674
4.856LeuLys: 4.856 ± 1.776
10.568LeuLeu: 10.568 ± 1.645
3.142LeuMet: 3.142 ± 0.762
3.999LeuAsn: 3.999 ± 1.082
4.57LeuPro: 4.57 ± 1.439
2.571LeuGln: 2.571 ± 0.689
6.855LeuArg: 6.855 ± 1.619
7.426LeuSer: 7.426 ± 1.212
3.713LeuThr: 3.713 ± 0.71
5.713LeuVal: 5.713 ± 0.905
1.999LeuTrp: 1.999 ± 0.795
3.713LeuTyr: 3.713 ± 0.807
0.0LeuXaa: 0.0 ± 0.0
Met
1.999MetAla: 1.999 ± 0.68
0.571MetCys: 0.571 ± 0.332
0.857MetAsp: 0.857 ± 0.504
3.713MetGlu: 3.713 ± 0.948
1.428MetPhe: 1.428 ± 0.782
2.856MetGly: 2.856 ± 0.511
0.571MetHis: 0.571 ± 0.484
0.571MetIle: 0.571 ± 0.311
1.143MetLys: 1.143 ± 0.25
2.571MetLeu: 2.571 ± 0.86
0.857MetMet: 0.857 ± 0.556
1.999MetAsn: 1.999 ± 0.771
0.857MetPro: 0.857 ± 0.396
0.286MetGln: 0.286 ± 0.242
2.856MetArg: 2.856 ± 0.648
1.428MetSer: 1.428 ± 0.494
1.428MetThr: 1.428 ± 0.347
1.999MetVal: 1.999 ± 0.291
0.286MetTrp: 0.286 ± 0.277
0.571MetTyr: 0.571 ± 0.314
0.0MetXaa: 0.0 ± 0.0
Asn
1.999AsnAla: 1.999 ± 0.915
0.857AsnCys: 0.857 ± 0.341
2.856AsnAsp: 2.856 ± 0.997
2.856AsnGlu: 2.856 ± 0.6
2.856AsnPhe: 2.856 ± 0.798
1.999AsnGly: 1.999 ± 0.797
0.286AsnHis: 0.286 ± 0.277
3.142AsnIle: 3.142 ± 0.68
2.856AsnLys: 2.856 ± 0.631
2.856AsnLeu: 2.856 ± 0.487
0.286AsnMet: 0.286 ± 0.355
1.999AsnAsn: 1.999 ± 0.493
3.713AsnPro: 3.713 ± 0.957
1.714AsnGln: 1.714 ± 0.753
1.999AsnArg: 1.999 ± 0.712
3.713AsnSer: 3.713 ± 0.639
3.142AsnThr: 3.142 ± 0.607
1.999AsnVal: 1.999 ± 0.715
0.857AsnTrp: 0.857 ± 0.437
1.714AsnTyr: 1.714 ± 0.929
0.0AsnXaa: 0.0 ± 0.0
Pro
3.428ProAla: 3.428 ± 0.613
0.857ProCys: 0.857 ± 0.556
2.285ProAsp: 2.285 ± 0.863
3.428ProGlu: 3.428 ± 1.359
1.714ProPhe: 1.714 ± 0.651
3.428ProGly: 3.428 ± 1.255
0.571ProHis: 0.571 ± 0.352
2.856ProIle: 2.856 ± 0.357
3.142ProLys: 3.142 ± 1.192
2.571ProLeu: 2.571 ± 0.444
0.286ProMet: 0.286 ± 0.242
0.857ProAsn: 0.857 ± 0.267
2.285ProPro: 2.285 ± 0.635
1.428ProGln: 1.428 ± 0.439
2.285ProArg: 2.285 ± 0.76
2.856ProSer: 2.856 ± 0.675
2.571ProThr: 2.571 ± 0.741
3.142ProVal: 3.142 ± 0.531
0.571ProTrp: 0.571 ± 0.303
2.285ProTyr: 2.285 ± 0.679
0.0ProXaa: 0.0 ± 0.0
Gln
2.856GlnAla: 2.856 ± 0.83
0.571GlnCys: 0.571 ± 0.272
1.428GlnAsp: 1.428 ± 0.562
3.428GlnGlu: 3.428 ± 0.98
1.428GlnPhe: 1.428 ± 0.347
1.999GlnGly: 1.999 ± 0.552
1.143GlnHis: 1.143 ± 0.466
1.143GlnIle: 1.143 ± 0.795
1.999GlnLys: 1.999 ± 0.5
3.713GlnLeu: 3.713 ± 1.104
1.714GlnMet: 1.714 ± 0.574
0.286GlnAsn: 0.286 ± 0.242
1.714GlnPro: 1.714 ± 0.525
0.571GlnGln: 0.571 ± 0.314
1.143GlnArg: 1.143 ± 0.248
0.571GlnSer: 0.571 ± 0.55
1.428GlnThr: 1.428 ± 0.666
1.999GlnVal: 1.999 ± 1.016
0.286GlnTrp: 0.286 ± 0.242
1.143GlnTyr: 1.143 ± 0.628
0.0GlnXaa: 0.0 ± 0.0
Arg
3.428ArgAla: 3.428 ± 0.812
1.999ArgCys: 1.999 ± 0.731
2.285ArgAsp: 2.285 ± 0.787
5.427ArgGlu: 5.427 ± 1.213
1.999ArgPhe: 1.999 ± 0.545
2.285ArgGly: 2.285 ± 0.612
1.714ArgHis: 1.714 ± 0.871
2.571ArgIle: 2.571 ± 0.603
5.713ArgLys: 5.713 ± 1.113
6.284ArgLeu: 6.284 ± 0.904
2.856ArgMet: 2.856 ± 0.228
2.285ArgAsn: 2.285 ± 0.534
2.285ArgPro: 2.285 ± 0.584
3.142ArgGln: 3.142 ± 0.895
3.999ArgArg: 3.999 ± 1.159
3.999ArgSer: 3.999 ± 0.837
3.428ArgThr: 3.428 ± 0.688
3.428ArgVal: 3.428 ± 0.86
0.571ArgTrp: 0.571 ± 0.417
1.714ArgTyr: 1.714 ± 0.233
0.0ArgXaa: 0.0 ± 0.0
Ser
5.713SerAla: 5.713 ± 1.215
0.286SerCys: 0.286 ± 0.242
1.999SerAsp: 1.999 ± 0.407
3.999SerGlu: 3.999 ± 1.484
3.999SerPhe: 3.999 ± 1.119
4.856SerGly: 4.856 ± 1.192
3.142SerHis: 3.142 ± 0.47
3.142SerIle: 3.142 ± 0.975
5.998SerLys: 5.998 ± 1.951
6.855SerLeu: 6.855 ± 0.265
0.857SerMet: 0.857 ± 0.538
3.142SerAsn: 3.142 ± 0.453
0.857SerPro: 0.857 ± 0.32
1.999SerGln: 1.999 ± 0.662
4.57SerArg: 4.57 ± 0.909
4.57SerSer: 4.57 ± 0.662
3.142SerThr: 3.142 ± 0.885
5.998SerVal: 5.998 ± 1.013
1.428SerTrp: 1.428 ± 0.604
1.999SerTyr: 1.999 ± 0.513
0.0SerXaa: 0.0 ± 0.0
Thr
4.856ThrAla: 4.856 ± 1.358
1.143ThrCys: 1.143 ± 0.464
3.142ThrAsp: 3.142 ± 1.162
3.428ThrGlu: 3.428 ± 0.514
1.428ThrPhe: 1.428 ± 0.73
3.428ThrGly: 3.428 ± 0.882
1.428ThrHis: 1.428 ± 0.403
2.571ThrIle: 2.571 ± 0.94
3.999ThrLys: 3.999 ± 0.536
5.998ThrLeu: 5.998 ± 1.152
1.143ThrMet: 1.143 ± 0.527
1.714ThrAsn: 1.714 ± 0.301
3.713ThrPro: 3.713 ± 0.807
1.714ThrGln: 1.714 ± 0.583
4.57ThrArg: 4.57 ± 0.971
3.428ThrSer: 3.428 ± 0.705
2.856ThrThr: 2.856 ± 0.533
4.57ThrVal: 4.57 ± 1.323
1.428ThrTrp: 1.428 ± 0.403
2.571ThrTyr: 2.571 ± 0.712
0.0ThrXaa: 0.0 ± 0.0
Val
3.713ValAla: 3.713 ± 0.953
1.714ValCys: 1.714 ± 0.536
2.856ValAsp: 2.856 ± 0.55
5.713ValGlu: 5.713 ± 0.548
1.714ValPhe: 1.714 ± 0.659
4.57ValGly: 4.57 ± 1.173
1.143ValHis: 1.143 ± 0.444
3.428ValIle: 3.428 ± 0.608
4.57ValLys: 4.57 ± 1.04
5.998ValLeu: 5.998 ± 1.444
1.999ValMet: 1.999 ± 0.692
2.571ValAsn: 2.571 ± 0.802
2.571ValPro: 2.571 ± 0.923
0.857ValGln: 0.857 ± 0.396
3.713ValArg: 3.713 ± 0.73
4.57ValSer: 4.57 ± 0.696
4.856ValThr: 4.856 ± 0.572
3.428ValVal: 3.428 ± 0.529
1.428ValTrp: 1.428 ± 0.74
2.856ValTyr: 2.856 ± 0.915
0.0ValXaa: 0.0 ± 0.0
Trp
1.714TrpAla: 1.714 ± 0.511
0.286TrpCys: 0.286 ± 0.232
1.714TrpAsp: 1.714 ± 0.53
1.143TrpGlu: 1.143 ± 0.564
0.857TrpPhe: 0.857 ± 0.543
1.143TrpGly: 1.143 ± 0.631
0.286TrpHis: 0.286 ± 0.277
0.571TrpIle: 0.571 ± 0.484
1.999TrpLys: 1.999 ± 0.638
1.428TrpLeu: 1.428 ± 0.42
1.143TrpMet: 1.143 ± 0.25
1.143TrpAsn: 1.143 ± 0.444
0.571TrpPro: 0.571 ± 0.272
0.571TrpGln: 0.571 ± 0.272
1.428TrpArg: 1.428 ± 0.464
1.714TrpSer: 1.714 ± 0.561
0.0TrpThr: 0.0 ± 0.0
2.571TrpVal: 2.571 ± 0.969
0.571TrpTrp: 0.571 ± 0.288
0.286TrpTyr: 0.286 ± 0.254
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.143TyrAla: 1.143 ± 0.622
0.571TyrCys: 0.571 ± 0.332
2.285TyrAsp: 2.285 ± 0.612
0.857TyrGlu: 0.857 ± 0.315
1.143TyrPhe: 1.143 ± 0.622
2.285TyrGly: 2.285 ± 0.549
0.286TyrHis: 0.286 ± 0.275
1.143TyrIle: 1.143 ± 0.443
2.856TyrLys: 2.856 ± 1.065
5.141TyrLeu: 5.141 ± 0.918
0.286TyrMet: 0.286 ± 0.242
1.714TyrAsn: 1.714 ± 0.594
1.714TyrPro: 1.714 ± 0.453
1.428TyrGln: 1.428 ± 0.57
2.285TyrArg: 2.285 ± 0.787
1.143TyrSer: 1.143 ± 0.528
2.285TyrThr: 2.285 ± 0.634
1.428TyrVal: 1.428 ± 0.625
0.571TyrTrp: 0.571 ± 0.314
1.428TyrTyr: 1.428 ± 0.42
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3502 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski