Amino acid dipepetide frequency for Chengkuizengella sp. YPA3-1-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.998AlaAla: 3.998 ± 0.066	0.483AlaCys: 0.483 ± 0.021	2.732AlaAsp: 2.732 ± 0.049	3.868AlaGlu: 3.868 ± 0.056	2.514AlaPhe: 2.514 ± 0.049	4.117AlaGly: 4.117 ± 0.07	1.015AlaHis: 1.015 ± 0.031	4.993AlaIle: 4.993 ± 0.07	3.879AlaLys: 3.879 ± 0.063	5.61AlaLeu: 5.61 ± 0.07	1.527AlaMet: 1.527 ± 0.037	2.66AlaAsn: 2.66 ± 0.054	1.598AlaPro: 1.598 ± 0.038	1.813AlaGln: 1.813 ± 0.036	1.97AlaArg: 1.97 ± 0.044	3.535AlaSer: 3.535 ± 0.055	2.79AlaThr: 2.79 ± 0.053	4.09AlaVal: 4.09 ± 0.066	0.56AlaTrp: 0.56 ± 0.022	2.067AlaTyr: 2.067 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.421CysAla: 0.421 ± 0.018	0.143CysCys: 0.143 ± 0.012	0.431CysAsp: 0.431 ± 0.02	0.49CysGlu: 0.49 ± 0.021	0.347CysPhe: 0.347 ± 0.019	0.613CysGly: 0.613 ± 0.025	0.187CysHis: 0.187 ± 0.013	0.663CysIle: 0.663 ± 0.019	0.48CysLys: 0.48 ± 0.023	0.685CysLeu: 0.685 ± 0.026	0.174CysMet: 0.174 ± 0.013	0.414CysAsn: 0.414 ± 0.022	0.353CysPro: 0.353 ± 0.018	0.197CysGln: 0.197 ± 0.012	0.259CysArg: 0.259 ± 0.016	0.587CysSer: 0.587 ± 0.024	0.403CysThr: 0.403 ± 0.017	0.502CysVal: 0.502 ± 0.022	0.082CysTrp: 0.082 ± 0.007	0.298CysTyr: 0.298 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	2.805AspAla: 2.805 ± 0.059	0.414AspCys: 0.414 ± 0.018	2.809AspAsp: 2.809 ± 0.062	4.467AspGlu: 4.467 ± 0.071	2.649AspPhe: 2.649 ± 0.055	3.666AspGly: 3.666 ± 0.086	1.352AspHis: 1.352 ± 0.039	4.752AspIle: 4.752 ± 0.06	3.411AspLys: 3.411 ± 0.059	5.571AspLeu: 5.571 ± 0.078	1.345AspMet: 1.345 ± 0.029	2.388AspAsn: 2.388 ± 0.05	2.113AspPro: 2.113 ± 0.045	2.36AspGln: 2.36 ± 0.044	2.05AspArg: 2.05 ± 0.04	2.966AspSer: 2.966 ± 0.056	2.585AspThr: 2.585 ± 0.048	3.865AspVal: 3.865 ± 0.062	0.683AspTrp: 0.683 ± 0.028	2.41AspTyr: 2.41 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.278GluAla: 4.278 ± 0.069	0.45GluCys: 0.45 ± 0.02	4.082GluAsp: 4.082 ± 0.067	6.488GluGlu: 6.488 ± 0.11	2.684GluPhe: 2.684 ± 0.051	4.191GluGly: 4.191 ± 0.064	1.5GluHis: 1.5 ± 0.03	6.465GluIle: 6.465 ± 0.081	6.372GluLys: 6.372 ± 0.096	7.189GluLeu: 7.189 ± 0.091	2.276GluMet: 2.276 ± 0.041	4.278GluAsn: 4.278 ± 0.048	1.893GluPro: 1.893 ± 0.045	3.545GluGln: 3.545 ± 0.073	2.81GluArg: 2.81 ± 0.055	4.04GluSer: 4.04 ± 0.06	3.771GluThr: 3.771 ± 0.059	5.433GluVal: 5.433 ± 0.069	0.848GluTrp: 0.848 ± 0.03	2.631GluTyr: 2.631 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	2.344PheAla: 2.344 ± 0.042	0.357PheCys: 0.357 ± 0.019	2.722PheAsp: 2.722 ± 0.044	3.189PheGlu: 3.189 ± 0.053	2.186PhePhe: 2.186 ± 0.05	2.915PheGly: 2.915 ± 0.05	0.964PheHis: 0.964 ± 0.032	4.392PheIle: 4.392 ± 0.07	2.852PheLys: 2.852 ± 0.042	4.217PheLeu: 4.217 ± 0.074	1.146PheMet: 1.146 ± 0.039	2.42PheAsn: 2.42 ± 0.06	1.647PhePro: 1.647 ± 0.039	1.62PheGln: 1.62 ± 0.038	1.407PheArg: 1.407 ± 0.03	3.421PheSer: 3.421 ± 0.053	2.619PheThr: 2.619 ± 0.041	2.885PheVal: 2.885 ± 0.052	0.465PheTrp: 0.465 ± 0.019	1.713PheTyr: 1.713 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	3.811GlyAla: 3.811 ± 0.067	0.582GlyCys: 0.582 ± 0.025	3.26GlyAsp: 3.26 ± 0.057	4.413GlyGlu: 4.413 ± 0.067	3.207GlyPhe: 3.207 ± 0.061	4.251GlyGly: 4.251 ± 0.079	1.238GlyHis: 1.238 ± 0.036	5.903GlyIle: 5.903 ± 0.075	4.614GlyLys: 4.614 ± 0.064	5.914GlyLeu: 5.914 ± 0.088	1.749GlyMet: 1.749 ± 0.046	3.024GlyAsn: 3.024 ± 0.061	1.43GlyPro: 1.43 ± 0.033	1.997GlyGln: 1.997 ± 0.044	2.308GlyArg: 2.308 ± 0.049	4.019GlySer: 4.019 ± 0.071	3.774GlyThr: 3.774 ± 0.069	4.62GlyVal: 4.62 ± 0.071	0.769GlyTrp: 0.769 ± 0.029	2.737GlyTyr: 2.737 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.078HisAla: 1.078 ± 0.03	0.212HisCys: 0.212 ± 0.013	1.008HisAsp: 1.008 ± 0.03	1.386HisGlu: 1.386 ± 0.036	1.097HisPhe: 1.097 ± 0.031	1.23HisGly: 1.23 ± 0.03	0.733HisHis: 0.733 ± 0.031	1.768HisIle: 1.768 ± 0.036	1.217HisLys: 1.217 ± 0.028	2.122HisLeu: 2.122 ± 0.051	0.512HisMet: 0.512 ± 0.022	0.86HisAsn: 0.86 ± 0.03	1.024HisPro: 1.024 ± 0.03	0.959HisGln: 0.959 ± 0.031	0.773HisArg: 0.773 ± 0.026	1.3HisSer: 1.3 ± 0.038	1.079HisThr: 1.079 ± 0.036	1.291HisVal: 1.291 ± 0.035	0.237HisTrp: 0.237 ± 0.015	0.837HisTyr: 0.837 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.126IleAla: 5.126 ± 0.071	0.779IleCys: 0.779 ± 0.028	5.066IleAsp: 5.066 ± 0.075	6.795IleGlu: 6.795 ± 0.08	3.595IlePhe: 3.595 ± 0.058	5.76IleGly: 5.76 ± 0.083	1.991IleHis: 1.991 ± 0.048	6.96IleIle: 6.96 ± 0.098	5.604IleLys: 5.604 ± 0.071	7.756IleLeu: 7.756 ± 0.107	1.827IleMet: 1.827 ± 0.035	4.515IleAsn: 4.515 ± 0.066	3.528IlePro: 3.528 ± 0.055	3.874IleGln: 3.874 ± 0.072	3.081IleArg: 3.081 ± 0.055	6.191IleSer: 6.191 ± 0.083	4.882IleThr: 4.882 ± 0.068	5.731IleVal: 5.731 ± 0.071	0.757IleTrp: 0.757 ± 0.028	3.077IleTyr: 3.077 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	3.791LysAla: 3.791 ± 0.066	0.439LysCys: 0.439 ± 0.021	3.937LysAsp: 3.937 ± 0.058	6.383LysGlu: 6.383 ± 0.088	2.32LysPhe: 2.32 ± 0.048	4.116LysGly: 4.116 ± 0.062	1.474LysHis: 1.474 ± 0.038	5.633LysIle: 5.633 ± 0.069	6.143LysLys: 6.143 ± 0.092	6.385LysLeu: 6.385 ± 0.08	2.16LysMet: 2.16 ± 0.042	4.247LysAsn: 4.247 ± 0.064	2.163LysPro: 2.163 ± 0.041	3.375LysGln: 3.375 ± 0.056	2.804LysArg: 2.804 ± 0.048	4.074LysSer: 4.074 ± 0.057	3.754LysThr: 3.754 ± 0.066	4.844LysVal: 4.844 ± 0.059	0.836LysTrp: 0.836 ± 0.027	2.693LysTyr: 2.693 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	5.581LeuAla: 5.581 ± 0.075	0.764LeuCys: 0.764 ± 0.023	5.065LeuAsp: 5.065 ± 0.067	6.661LeuGlu: 6.661 ± 0.082	4.818LeuPhe: 4.818 ± 0.084	5.825LeuGly: 5.825 ± 0.079	1.839LeuHis: 1.839 ± 0.042	7.679LeuIle: 7.679 ± 0.096	7.137LeuLys: 7.137 ± 0.094	9.013LeuLeu: 9.013 ± 0.11	2.26LeuMet: 2.26 ± 0.05	5.635LeuAsn: 5.635 ± 0.079	3.672LeuPro: 3.672 ± 0.062	3.604LeuGln: 3.604 ± 0.054	3.235LeuArg: 3.235 ± 0.054	6.914LeuSer: 6.914 ± 0.079	5.334LeuThr: 5.334 ± 0.071	5.56LeuVal: 5.56 ± 0.075	0.878LeuTrp: 0.878 ± 0.029	3.194LeuTyr: 3.194 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.471MetAla: 1.471 ± 0.035	0.155MetCys: 0.155 ± 0.012	1.561MetAsp: 1.561 ± 0.028	1.815MetGlu: 1.815 ± 0.045	1.1MetPhe: 1.1 ± 0.031	1.567MetGly: 1.567 ± 0.037	0.37MetHis: 0.37 ± 0.017	2.589MetIle: 2.589 ± 0.051	2.405MetLys: 2.405 ± 0.047	2.315MetLeu: 2.315 ± 0.052	0.867MetMet: 0.867 ± 0.03	1.945MetAsn: 1.945 ± 0.038	0.812MetPro: 0.812 ± 0.025	0.804MetGln: 0.804 ± 0.027	0.941MetArg: 0.941 ± 0.028	1.756MetSer: 1.756 ± 0.038	1.339MetThr: 1.339 ± 0.035	1.652MetVal: 1.652 ± 0.044	0.184MetTrp: 0.184 ± 0.012	0.758MetTyr: 0.758 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	2.688AsnAla: 2.688 ± 0.058	0.358AsnCys: 0.358 ± 0.02	2.968AsnAsp: 2.968 ± 0.049	4.541AsnGlu: 4.541 ± 0.061	2.088AsnPhe: 2.088 ± 0.053	3.542AsnGly: 3.542 ± 0.065	1.364AsnHis: 1.364 ± 0.036	4.586AsnIle: 4.586 ± 0.074	4.133AsnLys: 4.133 ± 0.063	4.887AsnLeu: 4.887 ± 0.076	1.438AsnMet: 1.438 ± 0.036	3.066AsnAsn: 3.066 ± 0.073	2.245AsnPro: 2.245 ± 0.047	2.601AsnGln: 2.601 ± 0.058	2.054AsnArg: 2.054 ± 0.045	3.004AsnSer: 3.004 ± 0.063	2.815AsnThr: 2.815 ± 0.058	3.482AsnVal: 3.482 ± 0.055	0.632AsnTrp: 0.632 ± 0.025	2.009AsnTyr: 2.009 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	1.709ProAla: 1.709 ± 0.033	0.215ProCys: 0.215 ± 0.014	2.032ProAsp: 2.032 ± 0.041	2.777ProGlu: 2.777 ± 0.053	1.764ProPhe: 1.764 ± 0.035	1.944ProGly: 1.944 ± 0.044	0.709ProHis: 0.709 ± 0.026	3.109ProIle: 3.109 ± 0.055	2.128ProLys: 2.128 ± 0.046	3.189ProLeu: 3.189 ± 0.055	0.796ProMet: 0.796 ± 0.025	1.977ProAsn: 1.977 ± 0.045	0.955ProPro: 0.955 ± 0.031	1.097ProGln: 1.097 ± 0.033	0.988ProArg: 0.988 ± 0.031	2.367ProSer: 2.367 ± 0.046	1.997ProThr: 1.997 ± 0.046	2.32ProVal: 2.32 ± 0.046	0.371ProTrp: 0.371 ± 0.017	1.43ProTyr: 1.43 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.135GlnAla: 2.135 ± 0.045	0.255GlnCys: 0.255 ± 0.016	1.684GlnAsp: 1.684 ± 0.038	2.675GlnGlu: 2.675 ± 0.042	1.944GlnPhe: 1.944 ± 0.045	2.037GlnGly: 2.037 ± 0.038	0.776GlnHis: 0.776 ± 0.027	3.376GlnIle: 3.376 ± 0.05	2.953GlnLys: 2.953 ± 0.059	4.262GlnLeu: 4.262 ± 0.075	1.177GlnMet: 1.177 ± 0.034	2.122GlnAsn: 2.122 ± 0.043	1.199GlnPro: 1.199 ± 0.034	1.722GlnGln: 1.722 ± 0.046	1.363GlnArg: 1.363 ± 0.033	2.427GlnSer: 2.427 ± 0.047	2.051GlnThr: 2.051 ± 0.044	2.527GlnVal: 2.527 ± 0.045	0.442GlnTrp: 0.442 ± 0.02	1.638GlnTyr: 1.638 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	1.899ArgAla: 1.899 ± 0.039	0.299ArgCys: 0.299 ± 0.016	1.936ArgAsp: 1.936 ± 0.04	2.764ArgGlu: 2.764 ± 0.049	1.687ArgPhe: 1.687 ± 0.038	2.113ArgGly: 2.113 ± 0.041	0.628ArgHis: 0.628 ± 0.028	3.053ArgIle: 3.053 ± 0.051	2.812ArgLys: 2.812 ± 0.045	3.392ArgLeu: 3.392 ± 0.064	1.127ArgMet: 1.127 ± 0.034	2.014ArgAsn: 2.014 ± 0.04	1.014ArgPro: 1.014 ± 0.031	1.114ArgGln: 1.114 ± 0.037	1.38ArgArg: 1.38 ± 0.041	2.169ArgSer: 2.169 ± 0.048	1.857ArgThr: 1.857 ± 0.036	2.237ArgVal: 2.237 ± 0.044	0.425ArgTrp: 0.425 ± 0.022	1.415ArgTyr: 1.415 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	3.291SerAla: 3.291 ± 0.059	0.459SerCys: 0.459 ± 0.023	3.517SerAsp: 3.517 ± 0.07	4.486SerGlu: 4.486 ± 0.074	3.429SerPhe: 3.429 ± 0.061	4.413SerGly: 4.413 ± 0.068	1.225SerHis: 1.225 ± 0.032	6.061SerIle: 6.061 ± 0.077	4.34SerLys: 4.34 ± 0.065	6.213SerLeu: 6.213 ± 0.075	1.72SerMet: 1.72 ± 0.039	3.706SerAsn: 3.706 ± 0.065	2.019SerPro: 2.019 ± 0.039	2.194SerGln: 2.194 ± 0.04	2.091SerArg: 2.091 ± 0.04	4.657SerSer: 4.657 ± 0.071	3.576SerThr: 3.576 ± 0.054	4.121SerVal: 4.121 ± 0.066	0.711SerTrp: 0.711 ± 0.031	2.622SerTyr: 2.622 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	3.143ThrAla: 3.143 ± 0.059	0.375ThrCys: 0.375 ± 0.016	2.949ThrAsp: 2.949 ± 0.056	3.578ThrGlu: 3.578 ± 0.055	2.608ThrPhe: 2.608 ± 0.041	3.858ThrGly: 3.858 ± 0.06	1.048ThrHis: 1.048 ± 0.03	4.975ThrIle: 4.975 ± 0.069	3.355ThrLys: 3.355 ± 0.052	5.228ThrLeu: 5.228 ± 0.06	1.296ThrMet: 1.296 ± 0.033	2.964ThrAsn: 2.964 ± 0.054	2.174ThrPro: 2.174 ± 0.044	1.578ThrGln: 1.578 ± 0.035	1.683ThrArg: 1.683 ± 0.036	3.704ThrSer: 3.704 ± 0.071	3.178ThrThr: 3.178 ± 0.074	3.743ThrVal: 3.743 ± 0.065	0.614ThrTrp: 0.614 ± 0.027	2.318ThrTyr: 2.318 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	3.703ValAla: 3.703 ± 0.063	0.596ValCys: 0.596 ± 0.024	3.898ValAsp: 3.898 ± 0.065	4.922ValGlu: 4.922 ± 0.062	2.971ValPhe: 2.971 ± 0.052	4.306ValGly: 4.306 ± 0.076	1.288ValHis: 1.288 ± 0.037	5.804ValIle: 5.804 ± 0.079	4.559ValLys: 4.559 ± 0.069	6.104ValLeu: 6.104 ± 0.065	1.745ValMet: 1.745 ± 0.042	3.62ValAsn: 3.62 ± 0.05	2.301ValPro: 2.301 ± 0.039	2.391ValGln: 2.391 ± 0.049	2.274ValArg: 2.274 ± 0.052	4.682ValSer: 4.682 ± 0.063	3.842ValThr: 3.842 ± 0.058	4.536ValVal: 4.536 ± 0.066	0.635ValTrp: 0.635 ± 0.023	2.348ValTyr: 2.348 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.537TrpAla: 0.537 ± 0.022	0.078TrpCys: 0.078 ± 0.008	0.632TrpAsp: 0.632 ± 0.027	0.752TrpGlu: 0.752 ± 0.025	0.565TrpPhe: 0.565 ± 0.024	0.714TrpGly: 0.714 ± 0.03	0.186TrpHis: 0.186 ± 0.012	1.051TrpIle: 1.051 ± 0.035	0.74TrpLys: 0.74 ± 0.028	1.062TrpLeu: 1.062 ± 0.03	0.339TrpMet: 0.339 ± 0.019	0.656TrpAsn: 0.656 ± 0.024	0.23TrpPro: 0.23 ± 0.015	0.381TrpGln: 0.381 ± 0.017	0.366TrpArg: 0.366 ± 0.016	0.681TrpSer: 0.681 ± 0.027	0.57TrpThr: 0.57 ± 0.028	0.627TrpVal: 0.627 ± 0.023	0.143TrpTrp: 0.143 ± 0.011	0.396TrpTyr: 0.396 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.008TyrAla: 2.008 ± 0.044	0.315TyrCys: 0.315 ± 0.015	2.373TyrAsp: 2.373 ± 0.07	2.771TyrGlu: 2.771 ± 0.053	1.911TyrPhe: 1.911 ± 0.048	2.445TyrGly: 2.445 ± 0.049	0.837TyrHis: 0.837 ± 0.032	3.084TyrIle: 3.084 ± 0.05	2.437TyrLys: 2.437 ± 0.043	3.553TyrLeu: 3.553 ± 0.054	0.924TyrMet: 0.924 ± 0.032	1.991TyrAsn: 1.991 ± 0.046	1.505TyrPro: 1.505 ± 0.042	1.54TyrGln: 1.54 ± 0.037	1.496TyrArg: 1.496 ± 0.041	2.357TyrSer: 2.357 ± 0.05	2.152TyrThr: 2.152 ± 0.053	2.458TyrVal: 2.458 ± 0.051	0.434TyrTrp: 0.434 ± 0.02	1.685TyrTyr: 1.685 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3947 proteins (1225611 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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