Amino acid dipepetide frequency for Parascardovia denticolens DSM 10105 = JCM 12538

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.52AlaAla: 10.52 ± 0.178
0.934AlaCys: 0.934 ± 0.045
6.205AlaAsp: 6.205 ± 0.115
4.938AlaGlu: 4.938 ± 0.118
3.652AlaPhe: 3.652 ± 0.091
8.182AlaGly: 8.182 ± 0.137
2.055AlaHis: 2.055 ± 0.063
5.202AlaIle: 5.202 ± 0.098
4.293AlaLys: 4.293 ± 0.111
9.344AlaLeu: 9.344 ± 0.163
2.493AlaMet: 2.493 ± 0.075
2.759AlaAsn: 2.759 ± 0.082
3.591AlaPro: 3.591 ± 0.094
4.691AlaGln: 4.691 ± 0.101
5.746AlaArg: 5.746 ± 0.109
7.025AlaSer: 7.025 ± 0.129
4.915AlaThr: 4.915 ± 0.094
6.788AlaVal: 6.788 ± 0.109
1.34AlaTrp: 1.34 ± 0.055
2.752AlaTyr: 2.752 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
0.759CysAla: 0.759 ± 0.035
0.087CysCys: 0.087 ± 0.013
0.556CysAsp: 0.556 ± 0.029
0.392CysGlu: 0.392 ± 0.029
0.301CysPhe: 0.301 ± 0.026
0.877CysGly: 0.877 ± 0.047
0.203CysHis: 0.203 ± 0.022
0.365CysIle: 0.365 ± 0.027
0.264CysLys: 0.264 ± 0.023
1.084CysLeu: 1.084 ± 0.052
0.23CysMet: 0.23 ± 0.02
0.185CysAsn: 0.185 ± 0.021
0.517CysPro: 0.517 ± 0.033
0.415CysGln: 0.415 ± 0.025
0.492CysArg: 0.492 ± 0.032
0.576CysSer: 0.576 ± 0.035
0.362CysThr: 0.362 ± 0.023
0.556CysVal: 0.556 ± 0.033
0.109CysTrp: 0.109 ± 0.014
0.225CysTyr: 0.225 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
5.127AspAla: 5.127 ± 0.096
0.513AspCys: 0.513 ± 0.035
4.156AspAsp: 4.156 ± 0.112
4.29AspGlu: 4.29 ± 0.106
2.809AspPhe: 2.809 ± 0.075
4.976AspGly: 4.976 ± 0.096
1.303AspHis: 1.303 ± 0.05
3.008AspIle: 3.008 ± 0.076
2.974AspLys: 2.974 ± 0.089
6.234AspLeu: 6.234 ± 0.123
1.506AspMet: 1.506 ± 0.049
1.599AspAsn: 1.599 ± 0.058
3.548AspPro: 3.548 ± 0.082
3.256AspGln: 3.256 ± 0.089
3.876AspArg: 3.876 ± 0.107
4.755AspSer: 4.755 ± 0.102
2.575AspThr: 2.575 ± 0.068
3.817AspVal: 3.817 ± 0.106
0.923AspTrp: 0.923 ± 0.044
2.082AspTyr: 2.082 ± 0.071
0.0AspXaa: 0.0 ± 0.0
Glu
5.803GluAla: 5.803 ± 0.117
0.376GluCys: 0.376 ± 0.024
3.757GluAsp: 3.757 ± 0.093
4.593GluGlu: 4.593 ± 0.114
1.713GluPhe: 1.713 ± 0.058
4.6GluGly: 4.6 ± 0.103
1.069GluHis: 1.069 ± 0.045
3.017GluIle: 3.017 ± 0.079
3.243GluLys: 3.243 ± 0.098
4.372GluLeu: 4.372 ± 0.095
1.395GluMet: 1.395 ± 0.056
2.108GluAsn: 2.108 ± 0.065
2.14GluPro: 2.14 ± 0.068
2.133GluGln: 2.133 ± 0.069
3.466GluArg: 3.466 ± 0.099
3.716GluSer: 3.716 ± 0.086
3.138GluThr: 3.138 ± 0.082
3.432GluVal: 3.432 ± 0.084
0.684GluTrp: 0.684 ± 0.029
1.445GluTyr: 1.445 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
3.505PheAla: 3.505 ± 0.085
0.387PheCys: 0.387 ± 0.024
2.468PheAsp: 2.468 ± 0.062
1.684PheGlu: 1.684 ± 0.051
1.652PhePhe: 1.652 ± 0.067
3.081PheGly: 3.081 ± 0.085
0.925PheHis: 0.925 ± 0.043
2.033PheIle: 2.033 ± 0.064
1.265PheLys: 1.265 ± 0.053
3.734PheLeu: 3.734 ± 0.104
0.818PheMet: 0.818 ± 0.038
1.31PheAsn: 1.31 ± 0.051
1.55PhePro: 1.55 ± 0.062
1.208PheGln: 1.208 ± 0.04
1.791PheArg: 1.791 ± 0.066
2.91PheSer: 2.91 ± 0.07
2.262PheThr: 2.262 ± 0.069
2.582PheVal: 2.582 ± 0.068
0.44PheTrp: 0.44 ± 0.028
1.066PheTyr: 1.066 ± 0.053
0.0PheXaa: 0.0 ± 0.0
Gly
6.164GlyAla: 6.164 ± 0.13
0.617GlyCys: 0.617 ± 0.041
4.338GlyAsp: 4.338 ± 0.1
4.307GlyGlu: 4.307 ± 0.093
3.121GlyPhe: 3.121 ± 0.067
5.69GlyGly: 5.69 ± 0.124
1.67GlyHis: 1.67 ± 0.055
4.717GlyIle: 4.717 ± 0.113
4.733GlyLys: 4.733 ± 0.104
7.661GlyLeu: 7.661 ± 0.132
1.989GlyMet: 1.989 ± 0.065
2.395GlyAsn: 2.395 ± 0.077
2.869GlyPro: 2.869 ± 0.089
3.689GlyGln: 3.689 ± 0.082
5.256GlyArg: 5.256 ± 0.116
5.808GlySer: 5.808 ± 0.107
3.994GlyThr: 3.994 ± 0.086
5.35GlyVal: 5.35 ± 0.109
1.173GlyTrp: 1.173 ± 0.043
2.57GlyTyr: 2.57 ± 0.085
0.0GlyXaa: 0.0 ± 0.0
His
1.752HisAla: 1.752 ± 0.058
0.203HisCys: 0.203 ± 0.02
1.426HisAsp: 1.426 ± 0.052
1.258HisGlu: 1.258 ± 0.049
0.675HisPhe: 0.675 ± 0.034
1.72HisGly: 1.72 ± 0.065
0.528HisHis: 0.528 ± 0.034
1.062HisIle: 1.062 ± 0.048
0.747HisLys: 0.747 ± 0.033
1.754HisLeu: 1.754 ± 0.06
0.533HisMet: 0.533 ± 0.033
0.624HisAsn: 0.624 ± 0.032
1.436HisPro: 1.436 ± 0.057
0.955HisGln: 0.955 ± 0.042
1.31HisArg: 1.31 ± 0.053
1.214HisSer: 1.214 ± 0.043
1.005HisThr: 1.005 ± 0.046
1.488HisVal: 1.488 ± 0.052
0.26HisTrp: 0.26 ± 0.021
0.579HisTyr: 0.579 ± 0.034
0.0HisXaa: 0.0 ± 0.0
Ile
5.395IleAla: 5.395 ± 0.107
0.609IleCys: 0.609 ± 0.033
3.702IleAsp: 3.702 ± 0.083
2.598IleGlu: 2.598 ± 0.075
2.087IlePhe: 2.087 ± 0.076
4.108IleGly: 4.108 ± 0.102
1.155IleHis: 1.155 ± 0.048
3.461IleIle: 3.461 ± 0.098
2.121IleLys: 2.121 ± 0.072
5.011IleLeu: 5.011 ± 0.11
1.356IleMet: 1.356 ± 0.052
2.044IleAsn: 2.044 ± 0.069
3.04IlePro: 3.04 ± 0.078
1.709IleGln: 1.709 ± 0.056
3.172IleArg: 3.172 ± 0.08
4.184IleSer: 4.184 ± 0.088
2.989IleThr: 2.989 ± 0.086
4.165IleVal: 4.165 ± 0.1
0.606IleTrp: 0.606 ± 0.036
1.483IleTyr: 1.483 ± 0.054
0.0IleXaa: 0.0 ± 0.0
Lys
5.384LysAla: 5.384 ± 0.118
0.162LysCys: 0.162 ± 0.018
3.219LysAsp: 3.219 ± 0.078
3.201LysGlu: 3.201 ± 0.088
1.034LysPhe: 1.034 ± 0.049
3.461LysGly: 3.461 ± 0.1
0.845LysHis: 0.845 ± 0.043
2.295LysIle: 2.295 ± 0.073
2.914LysLys: 2.914 ± 0.091
3.301LysLeu: 3.301 ± 0.086
1.11LysMet: 1.11 ± 0.045
1.871LysAsn: 1.871 ± 0.065
2.131LysPro: 2.131 ± 0.066
1.736LysGln: 1.736 ± 0.067
2.768LysArg: 2.768 ± 0.068
3.003LysSer: 3.003 ± 0.086
3.081LysThr: 3.081 ± 0.089
2.998LysVal: 2.998 ± 0.086
0.483LysTrp: 0.483 ± 0.032
1.207LysTyr: 1.207 ± 0.044
0.0LysXaa: 0.0 ± 0.0
Leu
9.786LeuAla: 9.786 ± 0.164
0.986LeuCys: 0.986 ± 0.043
6.002LeuAsp: 6.002 ± 0.127
4.441LeuGlu: 4.441 ± 0.098
3.456LeuPhe: 3.456 ± 0.093
6.924LeuGly: 6.924 ± 0.124
1.795LeuHis: 1.795 ± 0.058
5.478LeuIle: 5.478 ± 0.117
3.801LeuLys: 3.801 ± 0.094
8.565LeuLeu: 8.565 ± 0.193
2.158LeuMet: 2.158 ± 0.059
2.917LeuAsn: 2.917 ± 0.077
4.915LeuPro: 4.915 ± 0.116
2.794LeuGln: 2.794 ± 0.074
5.216LeuArg: 5.216 ± 0.125
6.897LeuSer: 6.897 ± 0.121
5.844LeuThr: 5.844 ± 0.112
6.865LeuVal: 6.865 ± 0.142
1.08LeuTrp: 1.08 ± 0.046
2.278LeuTyr: 2.278 ± 0.067
0.0LeuXaa: 0.0 ± 0.0
Met
2.613MetAla: 2.613 ± 0.08
0.162MetCys: 0.162 ± 0.015
1.686MetAsp: 1.686 ± 0.064
1.354MetGlu: 1.354 ± 0.058
0.627MetPhe: 0.627 ± 0.038
1.941MetGly: 1.941 ± 0.061
0.429MetHis: 0.429 ± 0.029
1.34MetIle: 1.34 ± 0.05
1.381MetLys: 1.381 ± 0.046
1.862MetLeu: 1.862 ± 0.058
0.65MetMet: 0.65 ± 0.036
0.998MetAsn: 0.998 ± 0.046
1.253MetPro: 1.253 ± 0.045
0.674MetGln: 0.674 ± 0.032
1.504MetArg: 1.504 ± 0.049
1.609MetSer: 1.609 ± 0.055
2.048MetThr: 2.048 ± 0.066
1.848MetVal: 1.848 ± 0.059
0.235MetTrp: 0.235 ± 0.023
0.49MetTyr: 0.49 ± 0.03
0.0MetXaa: 0.0 ± 0.0
Asn
2.825AsnAla: 2.825 ± 0.089
0.244AsnCys: 0.244 ± 0.023
1.804AsnAsp: 1.804 ± 0.062
1.727AsnGlu: 1.727 ± 0.059
1.048AsnPhe: 1.048 ± 0.046
2.762AsnGly: 2.762 ± 0.084
0.716AsnHis: 0.716 ± 0.039
1.627AsnIle: 1.627 ± 0.049
1.533AsnLys: 1.533 ± 0.058
2.923AsnLeu: 2.923 ± 0.075
0.807AsnMet: 0.807 ± 0.041
1.037AsnAsn: 1.037 ± 0.053
2.422AsnPro: 2.422 ± 0.071
1.611AsnGln: 1.611 ± 0.054
2.042AsnArg: 2.042 ± 0.07
2.073AsnSer: 2.073 ± 0.072
1.542AsnThr: 1.542 ± 0.055
2.017AsnVal: 2.017 ± 0.068
0.415AsnTrp: 0.415 ± 0.032
0.918AsnTyr: 0.918 ± 0.043
0.0AsnXaa: 0.0 ± 0.0
Pro
5.031ProAla: 5.031 ± 0.101
0.364ProCys: 0.364 ± 0.032
3.227ProAsp: 3.227 ± 0.078
2.901ProGlu: 2.901 ± 0.083
1.768ProPhe: 1.768 ± 0.058
3.586ProGly: 3.586 ± 0.088
1.066ProHis: 1.066 ± 0.045
2.208ProIle: 2.208 ± 0.068
1.529ProLys: 1.529 ± 0.06
4.25ProLeu: 4.25 ± 0.092
1.002ProMet: 1.002 ± 0.044
1.247ProAsn: 1.247 ± 0.039
1.408ProPro: 1.408 ± 0.051
2.529ProGln: 2.529 ± 0.071
2.634ProArg: 2.634 ± 0.078
3.709ProSer: 3.709 ± 0.1
2.532ProThr: 2.532 ± 0.074
3.605ProVal: 3.605 ± 0.084
0.724ProTrp: 0.724 ± 0.038
1.394ProTyr: 1.394 ± 0.051
0.0ProXaa: 0.0 ± 0.0
Gln
5.788GlnAla: 5.788 ± 0.123
0.216GlnCys: 0.216 ± 0.019
2.406GlnAsp: 2.406 ± 0.069
3.256GlnGlu: 3.256 ± 0.085
1.023GlnPhe: 1.023 ± 0.044
3.636GlnGly: 3.636 ± 0.097
0.579GlnHis: 0.579 ± 0.034
2.105GlnIle: 2.105 ± 0.068
1.978GlnLys: 1.978 ± 0.076
3.247GlnLeu: 3.247 ± 0.085
0.955GlnMet: 0.955 ± 0.044
1.231GlnAsn: 1.231 ± 0.048
1.882GlnPro: 1.882 ± 0.071
1.632GlnGln: 1.632 ± 0.066
2.342GlnArg: 2.342 ± 0.072
2.327GlnSer: 2.327 ± 0.072
2.584GlnThr: 2.584 ± 0.07
3.265GlnVal: 3.265 ± 0.086
0.631GlnTrp: 0.631 ± 0.037
0.962GlnTyr: 0.962 ± 0.045
0.0GlnXaa: 0.0 ± 0.0
Arg
4.521ArgAla: 4.521 ± 0.095
0.458ArgCys: 0.458 ± 0.029
3.069ArgAsp: 3.069 ± 0.088
3.32ArgGlu: 3.32 ± 0.092
2.36ArgPhe: 2.36 ± 0.074
3.814ArgGly: 3.814 ± 0.101
1.365ArgHis: 1.365 ± 0.044
3.71ArgIle: 3.71 ± 0.08
3.5ArgLys: 3.5 ± 0.086
6.118ArgLeu: 6.118 ± 0.128
1.886ArgMet: 1.886 ± 0.061
2.026ArgAsn: 2.026 ± 0.063
2.757ArgPro: 2.757 ± 0.078
3.081ArgGln: 3.081 ± 0.084
4.587ArgArg: 4.587 ± 0.138
3.944ArgSer: 3.944 ± 0.099
3.311ArgThr: 3.311 ± 0.076
3.8ArgVal: 3.8 ± 0.093
0.838ArgTrp: 0.838 ± 0.045
1.841ArgTyr: 1.841 ± 0.066
0.0ArgXaa: 0.0 ± 0.0
Ser
6.688SerAla: 6.688 ± 0.112
0.558SerCys: 0.558 ± 0.036
4.4SerAsp: 4.4 ± 0.088
3.158SerGlu: 3.158 ± 0.085
2.823SerPhe: 2.823 ± 0.068
5.999SerGly: 5.999 ± 0.129
1.522SerHis: 1.522 ± 0.051
3.511SerIle: 3.511 ± 0.086
2.679SerLys: 2.679 ± 0.076
7.187SerLeu: 7.187 ± 0.128
1.739SerMet: 1.739 ± 0.058
2.016SerAsn: 2.016 ± 0.065
3.432SerPro: 3.432 ± 0.084
3.828SerGln: 3.828 ± 0.108
4.487SerArg: 4.487 ± 0.099
6.113SerSer: 6.113 ± 0.18
3.677SerThr: 3.677 ± 0.09
4.678SerVal: 4.678 ± 0.093
1.103SerTrp: 1.103 ± 0.045
2.249SerTyr: 2.249 ± 0.068
0.0SerXaa: 0.0 ± 0.0
Thr
5.359ThrAla: 5.359 ± 0.107
0.488ThrCys: 0.488 ± 0.029
3.495ThrAsp: 3.495 ± 0.086
2.518ThrGlu: 2.518 ± 0.073
2.08ThrPhe: 2.08 ± 0.066
4.673ThrGly: 4.673 ± 0.089
1.123ThrHis: 1.123 ± 0.048
3.513ThrIle: 3.513 ± 0.074
2.169ThrLys: 2.169 ± 0.069
5.004ThrLeu: 5.004 ± 0.1
1.485ThrMet: 1.485 ± 0.054
1.832ThrAsn: 1.832 ± 0.059
2.764ThrPro: 2.764 ± 0.077
1.889ThrGln: 1.889 ± 0.06
2.935ThrArg: 2.935 ± 0.084
3.794ThrSer: 3.794 ± 0.088
3.26ThrThr: 3.26 ± 0.085
5.077ThrVal: 5.077 ± 0.103
0.74ThrTrp: 0.74 ± 0.038
1.659ThrTyr: 1.659 ± 0.063
0.0ThrXaa: 0.0 ± 0.0
Val
6.692ValAla: 6.692 ± 0.109
0.734ValCys: 0.734 ± 0.039
4.922ValAsp: 4.922 ± 0.107
3.985ValGlu: 3.985 ± 0.096
2.775ValPhe: 2.775 ± 0.07
4.748ValGly: 4.748 ± 0.107
1.342ValHis: 1.342 ± 0.053
4.268ValIle: 4.268 ± 0.1
3.272ValLys: 3.272 ± 0.086
6.352ValLeu: 6.352 ± 0.137
1.6ValMet: 1.6 ± 0.051
2.44ValAsn: 2.44 ± 0.076
3.151ValPro: 3.151 ± 0.074
2.149ValGln: 2.149 ± 0.063
3.871ValArg: 3.871 ± 0.083
5.412ValSer: 5.412 ± 0.111
4.482ValThr: 4.482 ± 0.104
5.419ValVal: 5.419 ± 0.11
0.891ValTrp: 0.891 ± 0.045
1.862ValTyr: 1.862 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
1.178TrpAla: 1.178 ± 0.043
0.128TrpCys: 0.128 ± 0.015
0.797TrpAsp: 0.797 ± 0.036
0.732TrpGlu: 0.732 ± 0.033
0.54TrpPhe: 0.54 ± 0.036
0.909TrpGly: 0.909 ± 0.04
0.29TrpHis: 0.29 ± 0.023
0.782TrpIle: 0.782 ± 0.041
0.715TrpLys: 0.715 ± 0.037
1.413TrpLeu: 1.413 ± 0.054
0.399TrpMet: 0.399 ± 0.028
0.522TrpAsn: 0.522 ± 0.036
0.479TrpPro: 0.479 ± 0.029
0.574TrpGln: 0.574 ± 0.034
0.854TrpArg: 0.854 ± 0.051
0.866TrpSer: 0.866 ± 0.039
0.75TrpThr: 0.75 ± 0.037
0.765TrpVal: 0.765 ± 0.046
0.312TrpTrp: 0.312 ± 0.024
0.442TrpTyr: 0.442 ± 0.03
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.534TyrAla: 2.534 ± 0.071
0.328TyrCys: 0.328 ± 0.025
1.693TyrAsp: 1.693 ± 0.06
1.547TyrGlu: 1.547 ± 0.06
1.132TyrPhe: 1.132 ± 0.051
2.427TyrGly: 2.427 ± 0.074
0.549TyrHis: 0.549 ± 0.028
1.29TyrIle: 1.29 ± 0.052
1.091TyrLys: 1.091 ± 0.047
2.782TyrLeu: 2.782 ± 0.083
0.592TyrMet: 0.592 ± 0.037
0.93TyrAsn: 0.93 ± 0.054
1.426TyrPro: 1.426 ± 0.051
1.492TyrGln: 1.492 ± 0.054
1.957TyrArg: 1.957 ± 0.073
1.912TyrSer: 1.912 ± 0.057
1.506TyrThr: 1.506 ± 0.066
1.852TyrVal: 1.852 ± 0.059
0.463TyrTrp: 0.463 ± 0.03
0.902TyrTyr: 0.902 ± 0.045
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1679 proteins (561124 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski