Amino acid dipepetide frequency for Alistipes communis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.972AlaAla: 11.972 ± 0.2	1.254AlaCys: 1.254 ± 0.041	5.997AlaAsp: 5.997 ± 0.088	6.937AlaGlu: 6.937 ± 0.105	3.539AlaPhe: 3.539 ± 0.071	7.817AlaGly: 7.817 ± 0.102	1.459AlaHis: 1.459 ± 0.039	4.321AlaIle: 4.321 ± 0.077	3.552AlaLys: 3.552 ± 0.078	8.926AlaLeu: 8.926 ± 0.119	2.212AlaMet: 2.212 ± 0.058	2.751AlaAsn: 2.751 ± 0.059	3.514AlaPro: 3.514 ± 0.079	2.949AlaGln: 2.949 ± 0.062	5.65AlaArg: 5.65 ± 0.097	5.247AlaSer: 5.247 ± 0.076	4.945AlaThr: 4.945 ± 0.081	7.472AlaVal: 7.472 ± 0.107	1.124AlaTrp: 1.124 ± 0.039	3.276AlaTyr: 3.276 ± 0.064	0.0AlaXaa: 0.0 ± 0.0
Cys	1.026CysAla: 1.026 ± 0.036	0.261CysCys: 0.261 ± 0.018	0.923CysAsp: 0.923 ± 0.035	0.82CysGlu: 0.82 ± 0.03	0.494CysPhe: 0.494 ± 0.024	1.292CysGly: 1.292 ± 0.046	0.273CysHis: 0.273 ± 0.015	0.735CysIle: 0.735 ± 0.029	0.489CysLys: 0.489 ± 0.024	0.946CysLeu: 0.946 ± 0.031	0.256CysMet: 0.256 ± 0.014	0.503CysAsn: 0.503 ± 0.022	0.641CysPro: 0.641 ± 0.029	0.263CysGln: 0.263 ± 0.015	1.022CysArg: 1.022 ± 0.035	0.799CysSer: 0.799 ± 0.034	0.825CysThr: 0.825 ± 0.042	0.815CysVal: 0.815 ± 0.034	0.144CysTrp: 0.144 ± 0.012	0.579CysTyr: 0.579 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	5.809AspAla: 5.809 ± 0.087	0.824AspCys: 0.824 ± 0.029	3.682AspAsp: 3.682 ± 0.071	4.137AspGlu: 4.137 ± 0.075	2.876AspPhe: 2.876 ± 0.051	5.252AspGly: 5.252 ± 0.084	0.932AspHis: 0.932 ± 0.031	3.337AspIle: 3.337 ± 0.051	2.694AspLys: 2.694 ± 0.065	4.743AspLeu: 4.743 ± 0.072	1.386AspMet: 1.386 ± 0.041	2.22AspAsn: 2.22 ± 0.058	2.712AspPro: 2.712 ± 0.055	1.093AspGln: 1.093 ± 0.039	4.251AspArg: 4.251 ± 0.074	2.875AspSer: 2.875 ± 0.066	2.998AspThr: 2.998 ± 0.053	3.858AspVal: 3.858 ± 0.066	0.841AspTrp: 0.841 ± 0.031	3.036AspTyr: 3.036 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	6.389GluAla: 6.389 ± 0.111	0.699GluCys: 0.699 ± 0.025	2.479GluAsp: 2.479 ± 0.057	4.595GluGlu: 4.595 ± 0.086	2.483GluPhe: 2.483 ± 0.055	4.86GluGly: 4.86 ± 0.077	1.24GluHis: 1.24 ± 0.039	4.232GluIle: 4.232 ± 0.083	3.455GluLys: 3.455 ± 0.071	6.122GluLeu: 6.122 ± 0.102	1.84GluMet: 1.84 ± 0.05	2.654GluAsn: 2.654 ± 0.047	2.268GluPro: 2.268 ± 0.055	2.663GluGln: 2.663 ± 0.048	5.307GluArg: 5.307 ± 0.1	2.942GluSer: 2.942 ± 0.062	3.438GluThr: 3.438 ± 0.064	4.481GluVal: 4.481 ± 0.077	0.937GluTrp: 0.937 ± 0.034	2.506GluTyr: 2.506 ± 0.057	0.0GluXaa: 0.0 ± 0.0
Phe	3.791PheAla: 3.791 ± 0.066	0.555PheCys: 0.555 ± 0.025	3.168PheAsp: 3.168 ± 0.06	2.63PheGlu: 2.63 ± 0.049	1.759PhePhe: 1.759 ± 0.054	3.515PheGly: 3.515 ± 0.066	0.715PheHis: 0.715 ± 0.028	2.137PheIle: 2.137 ± 0.055	1.529PheLys: 1.529 ± 0.042	3.273PheLeu: 3.273 ± 0.071	0.964PheMet: 0.964 ± 0.03	1.63PheAsn: 1.63 ± 0.045	1.591PhePro: 1.591 ± 0.043	0.884PheGln: 0.884 ± 0.029	2.763PheArg: 2.763 ± 0.056	2.83PheSer: 2.83 ± 0.063	2.74PheThr: 2.74 ± 0.045	2.831PheVal: 2.831 ± 0.054	0.51PheTrp: 0.51 ± 0.024	1.68PheTyr: 1.68 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	6.32GlyAla: 6.32 ± 0.093	1.182GlyCys: 1.182 ± 0.045	4.472GlyAsp: 4.472 ± 0.068	4.899GlyGlu: 4.899 ± 0.073	3.136GlyPhe: 3.136 ± 0.054	6.049GlyGly: 6.049 ± 0.095	1.4GlyHis: 1.4 ± 0.033	4.734GlyIle: 4.734 ± 0.087	3.78GlyLys: 3.78 ± 0.07	5.997GlyLeu: 5.997 ± 0.094	1.985GlyMet: 1.985 ± 0.055	3.058GlyAsn: 3.058 ± 0.07	1.467GlyPro: 1.467 ± 0.038	2.138GlyGln: 2.138 ± 0.043	5.306GlyArg: 5.306 ± 0.091	4.361GlySer: 4.361 ± 0.074	4.566GlyThr: 4.566 ± 0.083	5.712GlyVal: 5.712 ± 0.088	1.217GlyTrp: 1.217 ± 0.039	3.617GlyTyr: 3.617 ± 0.072	0.0GlyXaa: 0.0 ± 0.0
His	1.442HisAla: 1.442 ± 0.037	0.303HisCys: 0.303 ± 0.016	1.112HisAsp: 1.112 ± 0.035	0.97HisGlu: 0.97 ± 0.035	0.801HisPhe: 0.801 ± 0.03	1.309HisGly: 1.309 ± 0.037	0.344HisHis: 0.344 ± 0.022	1.187HisIle: 1.187 ± 0.038	0.678HisLys: 0.678 ± 0.029	1.586HisLeu: 1.586 ± 0.046	0.32HisMet: 0.32 ± 0.019	0.765HisAsn: 0.765 ± 0.028	1.061HisPro: 1.061 ± 0.033	0.397HisGln: 0.397 ± 0.022	1.276HisArg: 1.276 ± 0.041	0.925HisSer: 0.925 ± 0.031	1.192HisThr: 1.192 ± 0.036	1.063HisVal: 1.063 ± 0.035	0.203HisTrp: 0.203 ± 0.016	0.848HisTyr: 0.848 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.692IleAla: 5.692 ± 0.09	0.773IleCys: 0.773 ± 0.033	4.208IleAsp: 4.208 ± 0.077	4.033IleGlu: 4.033 ± 0.067	2.026IlePhe: 2.026 ± 0.055	4.271IleGly: 4.271 ± 0.079	0.974IleHis: 0.974 ± 0.03	2.45IleIle: 2.45 ± 0.066	2.279IleLys: 2.279 ± 0.054	4.645IleLeu: 4.645 ± 0.085	0.95IleMet: 0.95 ± 0.034	1.998IleAsn: 1.998 ± 0.055	2.744IlePro: 2.744 ± 0.052	1.313IleGln: 1.313 ± 0.037	3.907IleArg: 3.907 ± 0.062	3.079IleSer: 3.079 ± 0.069	3.019IleThr: 3.019 ± 0.069	4.416IleVal: 4.416 ± 0.073	0.545IleTrp: 0.545 ± 0.026	2.136IleTyr: 2.136 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	3.822LysAla: 3.822 ± 0.07	0.432LysCys: 0.432 ± 0.027	2.142LysAsp: 2.142 ± 0.051	3.235LysGlu: 3.235 ± 0.068	1.651LysPhe: 1.651 ± 0.038	3.261LysGly: 3.261 ± 0.068	0.739LysHis: 0.739 ± 0.029	2.884LysIle: 2.884 ± 0.061	2.478LysLys: 2.478 ± 0.06	3.856LysLeu: 3.856 ± 0.073	1.348LysMet: 1.348 ± 0.035	2.004LysAsn: 2.004 ± 0.048	1.728LysPro: 1.728 ± 0.045	1.511LysGln: 1.511 ± 0.043	2.928LysArg: 2.928 ± 0.065	2.47LysSer: 2.47 ± 0.058	2.567LysThr: 2.567 ± 0.064	3.016LysVal: 3.016 ± 0.062	0.574LysTrp: 0.574 ± 0.025	2.038LysTyr: 2.038 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	8.326LeuAla: 8.326 ± 0.115	1.35LeuCys: 1.35 ± 0.035	5.175LeuAsp: 5.175 ± 0.077	4.66LeuGlu: 4.66 ± 0.075	4.314LeuPhe: 4.314 ± 0.086	6.127LeuGly: 6.127 ± 0.092	1.873LeuHis: 1.873 ± 0.043	4.098LeuIle: 4.098 ± 0.062	4.034LeuLys: 4.034 ± 0.069	9.058LeuLeu: 9.058 ± 0.153	2.061LeuMet: 2.061 ± 0.052	3.252LeuAsn: 3.252 ± 0.067	4.368LeuPro: 4.368 ± 0.069	2.684LeuGln: 2.684 ± 0.051	6.997LeuArg: 6.997 ± 0.102	6.303LeuSer: 6.303 ± 0.086	5.674LeuThr: 5.674 ± 0.079	5.501LeuVal: 5.501 ± 0.092	1.069LeuTrp: 1.069 ± 0.034	3.453LeuTyr: 3.453 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.178MetAla: 2.178 ± 0.048	0.242MetCys: 0.242 ± 0.016	1.11MetAsp: 1.11 ± 0.036	1.545MetGlu: 1.545 ± 0.04	0.858MetPhe: 0.858 ± 0.033	1.599MetGly: 1.599 ± 0.041	0.413MetHis: 0.413 ± 0.02	1.281MetIle: 1.281 ± 0.04	1.806MetLys: 1.806 ± 0.044	2.237MetLeu: 2.237 ± 0.052	0.615MetMet: 0.615 ± 0.026	1.119MetAsn: 1.119 ± 0.029	1.144MetPro: 1.144 ± 0.031	0.949MetGln: 0.949 ± 0.032	1.711MetArg: 1.711 ± 0.04	1.369MetSer: 1.369 ± 0.038	1.509MetThr: 1.509 ± 0.033	1.298MetVal: 1.298 ± 0.04	0.265MetTrp: 0.265 ± 0.017	0.693MetTyr: 0.693 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.15AsnAla: 3.15 ± 0.064	0.486AsnCys: 0.486 ± 0.025	2.218AsnAsp: 2.218 ± 0.047	2.062AsnGlu: 2.062 ± 0.048	1.538AsnPhe: 1.538 ± 0.047	3.079AsnGly: 3.079 ± 0.071	0.639AsnHis: 0.639 ± 0.026	2.486AsnIle: 2.486 ± 0.056	1.664AsnLys: 1.664 ± 0.051	3.309AsnLeu: 3.309 ± 0.059	0.894AsnMet: 0.894 ± 0.033	1.607AsnAsn: 1.607 ± 0.053	2.154AsnPro: 2.154 ± 0.049	0.937AsnGln: 0.937 ± 0.039	2.587AsnArg: 2.587 ± 0.064	2.009AsnSer: 2.009 ± 0.054	2.104AsnThr: 2.104 ± 0.048	2.581AsnVal: 2.581 ± 0.049	0.472AsnTrp: 0.472 ± 0.022	1.825AsnTyr: 1.825 ± 0.053	0.0AsnXaa: 0.0 ± 0.0
Pro	4.698ProAla: 4.698 ± 0.086	0.478ProCys: 0.478 ± 0.022	3.19ProAsp: 3.19 ± 0.058	3.508ProGlu: 3.508 ± 0.071	1.774ProPhe: 1.774 ± 0.045	2.44ProGly: 2.44 ± 0.06	0.726ProHis: 0.726 ± 0.028	1.989ProIle: 1.989 ± 0.045	1.561ProLys: 1.561 ± 0.042	3.674ProLeu: 3.674 ± 0.062	0.906ProMet: 0.906 ± 0.033	1.277ProAsn: 1.277 ± 0.036	1.124ProPro: 1.124 ± 0.039	1.537ProGln: 1.537 ± 0.046	2.062ProArg: 2.062 ± 0.051	2.538ProSer: 2.538 ± 0.056	2.217ProThr: 2.217 ± 0.049	3.312ProVal: 3.312 ± 0.068	0.49ProTrp: 0.49 ± 0.025	1.673ProTyr: 1.673 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	2.567GlnAla: 2.567 ± 0.058	0.295GlnCys: 0.295 ± 0.018	1.156GlnAsp: 1.156 ± 0.035	1.848GlnGlu: 1.848 ± 0.048	1.088GlnPhe: 1.088 ± 0.034	1.889GlnGly: 1.889 ± 0.046	0.567GlnHis: 0.567 ± 0.023	1.952GlnIle: 1.952 ± 0.049	1.471GlnLys: 1.471 ± 0.041	2.911GlnLeu: 2.911 ± 0.056	0.809GlnMet: 0.809 ± 0.027	1.339GlnAsn: 1.339 ± 0.044	1.261GlnPro: 1.261 ± 0.036	1.346GlnGln: 1.346 ± 0.04	2.179GlnArg: 2.179 ± 0.046	1.778GlnSer: 1.778 ± 0.044	2.006GlnThr: 2.006 ± 0.042	1.783GlnVal: 1.783 ± 0.042	0.427GlnTrp: 0.427 ± 0.025	1.169GlnTyr: 1.169 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	5.119ArgAla: 5.119 ± 0.091	0.879ArgCys: 0.879 ± 0.034	3.411ArgAsp: 3.411 ± 0.063	4.518ArgGlu: 4.518 ± 0.069	3.068ArgPhe: 3.068 ± 0.052	3.85ArgGly: 3.85 ± 0.068	1.375ArgHis: 1.375 ± 0.047	4.93ArgIle: 4.93 ± 0.075	3.11ArgLys: 3.11 ± 0.068	6.626ArgLeu: 6.626 ± 0.1	2.121ArgMet: 2.121 ± 0.055	2.768ArgAsn: 2.768 ± 0.049	2.807ArgPro: 2.807 ± 0.06	2.414ArgGln: 2.414 ± 0.062	5.626ArgArg: 5.626 ± 0.1	3.571ArgSer: 3.571 ± 0.065	4.176ArgThr: 4.176 ± 0.074	3.834ArgVal: 3.834 ± 0.069	1.001ArgTrp: 1.001 ± 0.036	3.251ArgTyr: 3.251 ± 0.062	0.0ArgXaa: 0.0 ± 0.0
Ser	5.125SerAla: 5.125 ± 0.083	0.731SerCys: 0.731 ± 0.029	3.553SerAsp: 3.553 ± 0.069	3.381SerGlu: 3.381 ± 0.062	2.718SerPhe: 2.718 ± 0.07	4.793SerGly: 4.793 ± 0.082	1.012SerHis: 1.012 ± 0.034	3.126SerIle: 3.126 ± 0.07	2.312SerLys: 2.312 ± 0.052	5.411SerLeu: 5.411 ± 0.081	1.229SerMet: 1.229 ± 0.042	1.988SerAsn: 1.988 ± 0.048	2.345SerPro: 2.345 ± 0.047	1.703SerGln: 1.703 ± 0.043	3.191SerArg: 3.191 ± 0.057	3.3SerSer: 3.3 ± 0.068	3.153SerThr: 3.153 ± 0.064	4.387SerVal: 4.387 ± 0.069	0.726SerTrp: 0.726 ± 0.028	2.647SerTyr: 2.647 ± 0.071	0.0SerXaa: 0.0 ± 0.0
Thr	5.796ThrAla: 5.796 ± 0.086	0.55ThrCys: 0.55 ± 0.027	3.546ThrAsp: 3.546 ± 0.064	3.445ThrGlu: 3.445 ± 0.066	2.589ThrPhe: 2.589 ± 0.05	4.743ThrGly: 4.743 ± 0.09	1.017ThrHis: 1.017 ± 0.034	3.323ThrIle: 3.323 ± 0.065	2.201ThrLys: 2.201 ± 0.061	6.17ThrLeu: 6.17 ± 0.085	1.11ThrMet: 1.11 ± 0.036	1.792ThrAsn: 1.792 ± 0.051	3.173ThrPro: 3.173 ± 0.056	1.738ThrGln: 1.738 ± 0.042	2.861ThrArg: 2.861 ± 0.055	3.034ThrSer: 3.034 ± 0.067	3.583ThrThr: 3.583 ± 0.072	5.029ThrVal: 5.029 ± 0.089	0.611ThrTrp: 0.611 ± 0.026	2.17ThrTyr: 2.17 ± 0.068	0.0ThrXaa: 0.0 ± 0.0
Val	7.122ValAla: 7.122 ± 0.095	1.053ValCys: 1.053 ± 0.036	4.245ValAsp: 4.245 ± 0.066	5.083ValGlu: 5.083 ± 0.077	2.508ValPhe: 2.508 ± 0.057	5.094ValGly: 5.094 ± 0.092	1.059ValHis: 1.059 ± 0.034	3.407ValIle: 3.407 ± 0.07	3.255ValLys: 3.255 ± 0.06	5.96ValLeu: 5.96 ± 0.086	1.605ValMet: 1.605 ± 0.04	2.53ValAsn: 2.53 ± 0.059	2.906ValPro: 2.906 ± 0.058	1.903ValGln: 1.903 ± 0.039	4.848ValArg: 4.848 ± 0.079	4.358ValSer: 4.358 ± 0.069	4.43ValThr: 4.43 ± 0.077	5.913ValVal: 5.913 ± 0.096	0.888ValTrp: 0.888 ± 0.032	2.514ValTyr: 2.514 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.886TrpAla: 0.886 ± 0.03	0.222TrpCys: 0.222 ± 0.015	0.649TrpAsp: 0.649 ± 0.026	0.747TrpGlu: 0.747 ± 0.031	0.526TrpPhe: 0.526 ± 0.026	0.982TrpGly: 0.982 ± 0.038	0.308TrpHis: 0.308 ± 0.017	0.747TrpIle: 0.747 ± 0.028	0.573TrpLys: 0.573 ± 0.025	1.256TrpLeu: 1.256 ± 0.036	0.4TrpMet: 0.4 ± 0.023	0.676TrpAsn: 0.676 ± 0.028	0.341TrpPro: 0.341 ± 0.02	0.47TrpGln: 0.47 ± 0.024	0.959TrpArg: 0.959 ± 0.034	0.819TrpSer: 0.819 ± 0.03	0.741TrpThr: 0.741 ± 0.034	0.762TrpVal: 0.762 ± 0.031	0.246TrpTrp: 0.246 ± 0.017	0.514TrpTyr: 0.514 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.683TyrAla: 3.683 ± 0.058	0.54TyrCys: 0.54 ± 0.025	3.12TyrAsp: 3.12 ± 0.07	2.538TyrGlu: 2.538 ± 0.062	1.75TyrPhe: 1.75 ± 0.046	3.176TyrGly: 3.176 ± 0.063	0.72TyrHis: 0.72 ± 0.026	2.103TyrIle: 2.103 ± 0.05	1.763TyrLys: 1.763 ± 0.055	3.671TyrLeu: 3.671 ± 0.067	0.929TyrMet: 0.929 ± 0.033	1.87TyrAsn: 1.87 ± 0.054	1.824TyrPro: 1.824 ± 0.049	0.948TyrGln: 0.948 ± 0.035	3.023TyrArg: 3.023 ± 0.064	2.222TyrSer: 2.222 ± 0.054	2.599TyrThr: 2.599 ± 0.065	2.614TyrVal: 2.614 ± 0.056	0.534TyrTrp: 0.534 ± 0.027	1.982TyrTyr: 1.982 ± 0.056	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2673 proteins (959588 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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