Amino acid dipepetide frequency for Microvirga lotononidis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.033AlaAla: 15.033 ± 0.119	1.079AlaCys: 1.079 ± 0.029	5.966AlaAsp: 5.966 ± 0.062	7.099AlaGlu: 7.099 ± 0.066	4.363AlaPhe: 4.363 ± 0.046	9.725AlaGly: 9.725 ± 0.096	2.199AlaHis: 2.199 ± 0.039	6.192AlaIle: 6.192 ± 0.068	4.073AlaLys: 4.073 ± 0.055	12.998AlaLeu: 12.998 ± 0.093	3.275AlaMet: 3.275 ± 0.048	2.681AlaAsn: 2.681 ± 0.047	5.311AlaPro: 5.311 ± 0.062	4.191AlaGln: 4.191 ± 0.051	8.195AlaArg: 8.195 ± 0.079	6.812AlaSer: 6.812 ± 0.067	5.729AlaThr: 5.729 ± 0.061	8.692AlaVal: 8.692 ± 0.079	1.503AlaTrp: 1.503 ± 0.031	2.596AlaTyr: 2.596 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.893CysAla: 0.893 ± 0.023	0.095CysCys: 0.095 ± 0.007	0.463CysAsp: 0.463 ± 0.016	0.431CysGlu: 0.431 ± 0.014	0.315CysPhe: 0.315 ± 0.01	0.816CysGly: 0.816 ± 0.022	0.242CysHis: 0.242 ± 0.011	0.391CysIle: 0.391 ± 0.014	0.197CysLys: 0.197 ± 0.01	0.797CysLeu: 0.797 ± 0.025	0.146CysMet: 0.146 ± 0.01	0.204CysAsn: 0.204 ± 0.01	0.421CysPro: 0.421 ± 0.014	0.218CysGln: 0.218 ± 0.01	0.697CysArg: 0.697 ± 0.019	0.49CysSer: 0.49 ± 0.016	0.419CysThr: 0.419 ± 0.015	0.539CysVal: 0.539 ± 0.016	0.108CysTrp: 0.108 ± 0.007	0.191CysTyr: 0.191 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.202AspAla: 6.202 ± 0.061	0.402AspCys: 0.402 ± 0.015	2.858AspAsp: 2.858 ± 0.046	3.638AspGlu: 3.638 ± 0.044	1.993AspPhe: 1.993 ± 0.039	4.82AspGly: 4.82 ± 0.065	1.202AspHis: 1.202 ± 0.029	2.91AspIle: 2.91 ± 0.043	1.701AspLys: 1.701 ± 0.034	6.158AspLeu: 6.158 ± 0.069	1.195AspMet: 1.195 ± 0.021	1.242AspAsn: 1.242 ± 0.026	3.621AspPro: 3.621 ± 0.049	1.85AspGln: 1.85 ± 0.031	4.375AspArg: 4.375 ± 0.054	1.989AspSer: 1.989 ± 0.036	2.496AspThr: 2.496 ± 0.055	4.152AspVal: 4.152 ± 0.051	0.92AspTrp: 0.92 ± 0.024	1.357AspTyr: 1.357 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	7.814GluAla: 7.814 ± 0.077	0.354GluCys: 0.354 ± 0.014	2.738GluAsp: 2.738 ± 0.04	3.382GluGlu: 3.382 ± 0.05	1.75GluPhe: 1.75 ± 0.03	4.257GluGly: 4.257 ± 0.055	1.257GluHis: 1.257 ± 0.029	3.441GluIle: 3.441 ± 0.04	2.028GluLys: 2.028 ± 0.036	5.261GluLeu: 5.261 ± 0.056	1.404GluMet: 1.404 ± 0.027	1.545GluAsn: 1.545 ± 0.027	2.952GluPro: 2.952 ± 0.038	2.184GluGln: 2.184 ± 0.041	5.591GluArg: 5.591 ± 0.07	2.48GluSer: 2.48 ± 0.034	3.577GluThr: 3.577 ± 0.043	3.847GluVal: 3.847 ± 0.05	0.741GluTrp: 0.741 ± 0.021	0.97GluTyr: 0.97 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.126PheAla: 4.126 ± 0.051	0.376PheCys: 0.376 ± 0.014	2.482PheAsp: 2.482 ± 0.035	2.131PheGlu: 2.131 ± 0.034	1.378PhePhe: 1.378 ± 0.032	3.545PheGly: 3.545 ± 0.049	0.744PheHis: 0.744 ± 0.021	1.737PheIle: 1.737 ± 0.033	1.102PheLys: 1.102 ± 0.025	3.41PheLeu: 3.41 ± 0.054	0.823PheMet: 0.823 ± 0.018	1.015PheAsn: 1.015 ± 0.024	1.605PhePro: 1.605 ± 0.029	1.128PheGln: 1.128 ± 0.019	2.335PheArg: 2.335 ± 0.033	2.256PheSer: 2.256 ± 0.037	1.975PheThr: 1.975 ± 0.035	2.855PheVal: 2.855 ± 0.038	0.587PheTrp: 0.587 ± 0.017	0.897PheTyr: 0.897 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	8.623GlyAla: 8.623 ± 0.084	0.789GlyCys: 0.789 ± 0.02	4.109GlyAsp: 4.109 ± 0.055	4.526GlyGlu: 4.526 ± 0.052	3.607GlyPhe: 3.607 ± 0.043	7.175GlyGly: 7.175 ± 0.128	1.9GlyHis: 1.9 ± 0.033	4.694GlyIle: 4.694 ± 0.049	2.955GlyLys: 2.955 ± 0.044	8.951GlyLeu: 8.951 ± 0.075	2.11GlyMet: 2.11 ± 0.036	2.3GlyAsn: 2.3 ± 0.057	3.676GlyPro: 3.676 ± 0.042	3.041GlyGln: 3.041 ± 0.041	6.347GlyArg: 6.347 ± 0.056	5.221GlySer: 5.221 ± 0.071	4.91GlyThr: 4.91 ± 0.068	5.736GlyVal: 5.736 ± 0.06	1.388GlyTrp: 1.388 ± 0.03	2.308GlyTyr: 2.308 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	2.281HisAla: 2.281 ± 0.037	0.213HisCys: 0.213 ± 0.01	1.255HisAsp: 1.255 ± 0.027	1.181HisGlu: 1.181 ± 0.025	0.797HisPhe: 0.797 ± 0.022	1.917HisGly: 1.917 ± 0.034	0.592HisHis: 0.592 ± 0.022	0.909HisIle: 0.909 ± 0.026	0.498HisLys: 0.498 ± 0.015	2.2HisLeu: 2.2 ± 0.037	0.471HisMet: 0.471 ± 0.015	0.475HisAsn: 0.475 ± 0.018	1.419HisPro: 1.419 ± 0.032	0.625HisGln: 0.625 ± 0.019	1.68HisArg: 1.68 ± 0.03	1.015HisSer: 1.015 ± 0.027	0.843HisThr: 0.843 ± 0.023	1.565HisVal: 1.565 ± 0.028	0.347HisTrp: 0.347 ± 0.013	0.526HisTyr: 0.526 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.974IleAla: 6.974 ± 0.065	0.479IleCys: 0.479 ± 0.017	3.412IleAsp: 3.412 ± 0.042	3.54IleGlu: 3.54 ± 0.051	1.622IlePhe: 1.622 ± 0.029	5.072IleGly: 5.072 ± 0.057	1.011IleHis: 1.011 ± 0.022	2.24IleIle: 2.24 ± 0.038	1.464IleLys: 1.464 ± 0.026	4.985IleLeu: 4.985 ± 0.063	1.028IleMet: 1.028 ± 0.024	1.322IleAsn: 1.322 ± 0.027	2.489IlePro: 2.489 ± 0.031	1.419IleGln: 1.419 ± 0.026	3.574IleArg: 3.574 ± 0.04	2.779IleSer: 2.779 ± 0.042	2.649IleThr: 2.649 ± 0.043	4.539IleVal: 4.539 ± 0.051	0.625IleTrp: 0.625 ± 0.021	1.139IleTyr: 1.139 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.425LysAla: 4.425 ± 0.058	0.146LysCys: 0.146 ± 0.009	1.88LysAsp: 1.88 ± 0.034	1.692LysGlu: 1.692 ± 0.036	0.824LysPhe: 0.824 ± 0.02	2.852LysGly: 2.852 ± 0.041	0.596LysHis: 0.596 ± 0.017	1.609LysIle: 1.609 ± 0.029	1.188LysLys: 1.188 ± 0.032	3.157LysLeu: 3.157 ± 0.047	0.669LysMet: 0.669 ± 0.023	0.905LysAsn: 0.905 ± 0.022	2.211LysPro: 2.211 ± 0.034	1.043LysGln: 1.043 ± 0.024	2.515LysArg: 2.515 ± 0.042	1.815LysSer: 1.815 ± 0.034	1.907LysThr: 1.907 ± 0.034	2.517LysVal: 2.517 ± 0.04	0.333LysTrp: 0.333 ± 0.014	0.571LysTyr: 0.571 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	12.904LeuAla: 12.904 ± 0.097	0.872LeuCys: 0.872 ± 0.017	6.049LeuAsp: 6.049 ± 0.062	5.409LeuGlu: 5.409 ± 0.067	3.571LeuPhe: 3.571 ± 0.05	8.306LeuGly: 8.306 ± 0.073	1.923LeuHis: 1.923 ± 0.029	5.21LeuIle: 5.21 ± 0.06	3.8LeuLys: 3.8 ± 0.049	9.707LeuLeu: 9.707 ± 0.109	2.315LeuMet: 2.315 ± 0.037	2.677LeuAsn: 2.677 ± 0.038	5.582LeuPro: 5.582 ± 0.057	2.984LeuGln: 2.984 ± 0.041	7.145LeuArg: 7.145 ± 0.074	6.816LeuSer: 6.816 ± 0.062	5.777LeuThr: 5.777 ± 0.057	7.89LeuVal: 7.89 ± 0.074	1.234LeuTrp: 1.234 ± 0.029	2.056LeuTyr: 2.056 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	2.923MetAla: 2.923 ± 0.034	0.134MetCys: 0.134 ± 0.009	1.099MetAsp: 1.099 ± 0.022	1.067MetGlu: 1.067 ± 0.021	0.623MetPhe: 0.623 ± 0.022	1.696MetGly: 1.696 ± 0.031	0.454MetHis: 0.454 ± 0.016	1.343MetIle: 1.343 ± 0.028	0.988MetLys: 0.988 ± 0.024	2.257MetLeu: 2.257 ± 0.04	0.614MetMet: 0.614 ± 0.021	0.795MetAsn: 0.795 ± 0.02	1.515MetPro: 1.515 ± 0.029	0.786MetGln: 0.786 ± 0.022	1.853MetArg: 1.853 ± 0.028	1.645MetSer: 1.645 ± 0.031	1.814MetThr: 1.814 ± 0.032	1.596MetVal: 1.596 ± 0.029	0.197MetTrp: 0.197 ± 0.01	0.287MetTyr: 0.287 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.08AsnAla: 3.08 ± 0.042	0.198AsnCys: 0.198 ± 0.011	1.521AsnAsp: 1.521 ± 0.039	1.337AsnGlu: 1.337 ± 0.025	0.876AsnPhe: 0.876 ± 0.021	2.532AsnGly: 2.532 ± 0.056	0.48AsnHis: 0.48 ± 0.016	1.223AsnIle: 1.223 ± 0.027	0.722AsnLys: 0.722 ± 0.021	2.723AsnLeu: 2.723 ± 0.039	0.528AsnMet: 0.528 ± 0.018	0.718AsnAsn: 0.718 ± 0.02	1.942AsnPro: 1.942 ± 0.036	0.797AsnGln: 0.797 ± 0.025	1.899AsnArg: 1.899 ± 0.033	1.263AsnSer: 1.263 ± 0.03	1.252AsnThr: 1.252 ± 0.024	1.999AsnVal: 1.999 ± 0.031	0.401AsnTrp: 0.401 ± 0.014	0.65AsnTyr: 0.65 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	5.946ProAla: 5.946 ± 0.061	0.319ProCys: 0.319 ± 0.011	3.634ProAsp: 3.634 ± 0.049	3.693ProGlu: 3.693 ± 0.045	2.034ProPhe: 2.034 ± 0.032	4.548ProGly: 4.548 ± 0.043	1.203ProHis: 1.203 ± 0.026	2.435ProIle: 2.435 ± 0.034	1.91ProLys: 1.91 ± 0.035	4.798ProLeu: 4.798 ± 0.059	1.221ProMet: 1.221 ± 0.024	1.531ProAsn: 1.531 ± 0.032	2.707ProPro: 2.707 ± 0.043	1.824ProGln: 1.824 ± 0.034	3.185ProArg: 3.185 ± 0.044	3.322ProSer: 3.322 ± 0.043	2.701ProThr: 2.701 ± 0.043	4.35ProVal: 4.35 ± 0.042	0.751ProTrp: 0.751 ± 0.019	1.245ProTyr: 1.245 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.452GlnAla: 4.452 ± 0.053	0.205GlnCys: 0.205 ± 0.011	1.779GlnAsp: 1.779 ± 0.031	1.753GlnGlu: 1.753 ± 0.034	1.037GlnPhe: 1.037 ± 0.021	2.658GlnGly: 2.658 ± 0.036	0.708GlnHis: 0.708 ± 0.018	1.87GlnIle: 1.87 ± 0.029	1.106GlnLys: 1.106 ± 0.026	2.745GlnLeu: 2.745 ± 0.037	0.823GlnMet: 0.823 ± 0.02	0.903GlnAsn: 0.903 ± 0.023	1.905GlnPro: 1.905 ± 0.03	1.281GlnGln: 1.281 ± 0.033	2.634GlnArg: 2.634 ± 0.046	1.899GlnSer: 1.899 ± 0.034	1.772GlnThr: 1.772 ± 0.037	2.543GlnVal: 2.543 ± 0.041	0.422GlnTrp: 0.422 ± 0.015	0.626GlnTyr: 0.626 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	7.509ArgAla: 7.509 ± 0.07	0.554ArgCys: 0.554 ± 0.018	4.036ArgAsp: 4.036 ± 0.045	4.51ArgGlu: 4.51 ± 0.057	3.035ArgPhe: 3.035 ± 0.046	4.887ArgGly: 4.887 ± 0.05	1.821ArgHis: 1.821 ± 0.03	4.394ArgIle: 4.394 ± 0.05	2.399ArgLys: 2.399 ± 0.038	8.269ArgLeu: 8.269 ± 0.076	1.956ArgMet: 1.956 ± 0.033	1.951ArgAsn: 1.951 ± 0.03	3.764ArgPro: 3.764 ± 0.052	2.887ArgGln: 2.887 ± 0.039	6.247ArgArg: 6.247 ± 0.088	4.306ArgSer: 4.306 ± 0.058	3.739ArgThr: 3.739 ± 0.044	5.016ArgVal: 5.016 ± 0.054	1.079ArgTrp: 1.079 ± 0.024	1.845ArgTyr: 1.845 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	6.101SerAla: 6.101 ± 0.061	0.448SerCys: 0.448 ± 0.017	3.064SerAsp: 3.064 ± 0.04	2.938SerGlu: 2.938 ± 0.036	2.355SerPhe: 2.355 ± 0.034	5.753SerGly: 5.753 ± 0.07	1.211SerHis: 1.211 ± 0.026	2.929SerIle: 2.929 ± 0.04	1.665SerLys: 1.665 ± 0.032	6.143SerLeu: 6.143 ± 0.058	1.329SerMet: 1.329 ± 0.025	1.457SerAsn: 1.457 ± 0.032	3.209SerPro: 3.209 ± 0.046	1.754SerGln: 1.754 ± 0.025	4.114SerArg: 4.114 ± 0.048	3.452SerSer: 3.452 ± 0.054	2.946SerThr: 2.946 ± 0.046	4.114SerVal: 4.114 ± 0.048	0.855SerTrp: 0.855 ± 0.024	1.35SerTyr: 1.35 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	5.876ThrAla: 5.876 ± 0.065	0.415ThrCys: 0.415 ± 0.014	2.714ThrAsp: 2.714 ± 0.047	2.677ThrGlu: 2.677 ± 0.033	2.134ThrPhe: 2.134 ± 0.038	5.051ThrGly: 5.051 ± 0.057	1.023ThrHis: 1.023 ± 0.025	3.213ThrIle: 3.213 ± 0.047	1.618ThrLys: 1.618 ± 0.029	6.042ThrLeu: 6.042 ± 0.067	1.24ThrMet: 1.24 ± 0.024	1.373ThrAsn: 1.373 ± 0.026	3.192ThrPro: 3.192 ± 0.046	1.505ThrGln: 1.505 ± 0.026	3.461ThrArg: 3.461 ± 0.042	2.98ThrSer: 2.98 ± 0.044	2.898ThrThr: 2.898 ± 0.046	4.333ThrVal: 4.333 ± 0.055	0.783ThrTrp: 0.783 ± 0.022	1.33ThrTyr: 1.33 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	8.781ValAla: 8.781 ± 0.065	0.64ValCys: 0.64 ± 0.019	3.936ValAsp: 3.936 ± 0.054	4.708ValGlu: 4.708 ± 0.045	2.781ValPhe: 2.781 ± 0.041	5.656ValGly: 5.656 ± 0.064	1.416ValHis: 1.416 ± 0.03	4.002ValIle: 4.002 ± 0.044	2.353ValLys: 2.353 ± 0.041	7.751ValLeu: 7.751 ± 0.061	1.799ValMet: 1.799 ± 0.031	1.963ValAsn: 1.963 ± 0.034	3.922ValPro: 3.922 ± 0.047	2.332ValGln: 2.332 ± 0.04	5.213ValArg: 5.213 ± 0.057	4.59ValSer: 4.59 ± 0.046	4.553ValThr: 4.553 ± 0.05	5.903ValVal: 5.903 ± 0.066	0.88ValTrp: 0.88 ± 0.024	1.536ValTyr: 1.536 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.27TrpAla: 1.27 ± 0.027	0.128TrpCys: 0.128 ± 0.008	0.664TrpAsp: 0.664 ± 0.02	0.596TrpGlu: 0.596 ± 0.018	0.539TrpPhe: 0.539 ± 0.015	0.939TrpGly: 0.939 ± 0.025	0.368TrpHis: 0.368 ± 0.014	0.742TrpIle: 0.742 ± 0.021	0.451TrpLys: 0.451 ± 0.015	1.632TrpLeu: 1.632 ± 0.033	0.357TrpMet: 0.357 ± 0.014	0.472TrpAsn: 0.472 ± 0.016	0.728TrpPro: 0.728 ± 0.02	0.561TrpGln: 0.561 ± 0.018	1.262TrpArg: 1.262 ± 0.027	0.893TrpSer: 0.893 ± 0.019	0.801TrpThr: 0.801 ± 0.018	0.839TrpVal: 0.839 ± 0.021	0.243TrpTrp: 0.243 ± 0.011	0.286TrpTyr: 0.286 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.503TyrAla: 2.503 ± 0.04	0.227TyrCys: 0.227 ± 0.011	1.42TyrAsp: 1.42 ± 0.03	1.266TyrGlu: 1.266 ± 0.026	0.872TyrPhe: 0.872 ± 0.02	2.162TyrGly: 2.162 ± 0.035	0.457TyrHis: 0.457 ± 0.018	0.878TyrIle: 0.878 ± 0.022	0.637TyrLys: 0.637 ± 0.018	2.245TyrLeu: 2.245 ± 0.035	0.38TyrMet: 0.38 ± 0.013	0.613TyrAsn: 0.613 ± 0.019	1.188TyrPro: 1.188 ± 0.029	0.712TyrGln: 0.712 ± 0.021	1.883TyrArg: 1.883 ± 0.034	1.167TyrSer: 1.167 ± 0.026	1.096TyrThr: 1.096 ± 0.027	1.687TyrVal: 1.687 ± 0.031	0.373TyrTrp: 0.373 ± 0.015	0.629TyrTyr: 0.629 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6918 proteins (1985803 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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