Amino acid dipepetide frequency for Mesorhizobium amorphae CCNWGS0123

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.981AlaAla: 16.981 ± 0.134	1.02AlaCys: 1.02 ± 0.024	7.049AlaAsp: 7.049 ± 0.068	7.473AlaGlu: 7.473 ± 0.074	4.673AlaPhe: 4.673 ± 0.048	11.026AlaGly: 11.026 ± 0.091	2.177AlaHis: 2.177 ± 0.037	6.872AlaIle: 6.872 ± 0.058	4.641AlaLys: 4.641 ± 0.06	12.871AlaLeu: 12.871 ± 0.104	3.575AlaMet: 3.575 ± 0.041	3.14AlaAsn: 3.14 ± 0.038	5.069AlaPro: 5.069 ± 0.064	3.456AlaGln: 3.456 ± 0.043	8.215AlaArg: 8.215 ± 0.077	6.773AlaSer: 6.773 ± 0.063	6.081AlaThr: 6.081 ± 0.057	8.803AlaVal: 8.803 ± 0.077	1.487AlaTrp: 1.487 ± 0.027	2.65AlaTyr: 2.65 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.925CysAla: 0.925 ± 0.019	0.127CysCys: 0.127 ± 0.008	0.498CysAsp: 0.498 ± 0.015	0.424CysGlu: 0.424 ± 0.013	0.343CysPhe: 0.343 ± 0.013	0.882CysGly: 0.882 ± 0.025	0.239CysHis: 0.239 ± 0.011	0.393CysIle: 0.393 ± 0.013	0.201CysLys: 0.201 ± 0.009	0.791CysLeu: 0.791 ± 0.021	0.159CysMet: 0.159 ± 0.008	0.225CysAsn: 0.225 ± 0.011	0.399CysPro: 0.399 ± 0.016	0.223CysGln: 0.223 ± 0.011	0.637CysArg: 0.637 ± 0.018	0.476CysSer: 0.476 ± 0.017	0.416CysThr: 0.416 ± 0.015	0.613CysVal: 0.613 ± 0.019	0.135CysTrp: 0.135 ± 0.007	0.213CysTyr: 0.213 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.756AspAla: 6.756 ± 0.062	0.513AspCys: 0.513 ± 0.016	3.143AspAsp: 3.143 ± 0.046	3.423AspGlu: 3.423 ± 0.049	2.357AspPhe: 2.357 ± 0.038	5.258AspGly: 5.258 ± 0.06	1.278AspHis: 1.278 ± 0.023	3.405AspIle: 3.405 ± 0.048	2.003AspLys: 2.003 ± 0.036	5.638AspLeu: 5.638 ± 0.055	1.389AspMet: 1.389 ± 0.026	1.454AspAsn: 1.454 ± 0.03	3.334AspPro: 3.334 ± 0.038	1.796AspGln: 1.796 ± 0.031	4.314AspArg: 4.314 ± 0.05	2.147AspSer: 2.147 ± 0.037	2.625AspThr: 2.625 ± 0.047	4.114AspVal: 4.114 ± 0.058	0.966AspTrp: 0.966 ± 0.019	1.475AspTyr: 1.475 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	7.432GluAla: 7.432 ± 0.068	0.369GluCys: 0.369 ± 0.013	2.614GluAsp: 2.614 ± 0.036	2.922GluGlu: 2.922 ± 0.053	1.894GluPhe: 1.894 ± 0.03	3.966GluGly: 3.966 ± 0.043	1.208GluHis: 1.208 ± 0.026	3.6GluIle: 3.6 ± 0.046	2.566GluLys: 2.566 ± 0.041	5.298GluLeu: 5.298 ± 0.055	1.549GluMet: 1.549 ± 0.027	1.622GluAsn: 1.622 ± 0.03	2.765GluPro: 2.765 ± 0.045	2.043GluGln: 2.043 ± 0.04	4.746GluArg: 4.746 ± 0.068	2.226GluSer: 2.226 ± 0.032	3.428GluThr: 3.428 ± 0.044	3.726GluVal: 3.726 ± 0.046	0.669GluTrp: 0.669 ± 0.019	0.947GluTyr: 0.947 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	4.795PheAla: 4.795 ± 0.053	0.4PheCys: 0.4 ± 0.015	2.802PheAsp: 2.802 ± 0.037	2.268PheGlu: 2.268 ± 0.035	1.569PhePhe: 1.569 ± 0.03	3.881PheGly: 3.881 ± 0.044	0.803PheHis: 0.803 ± 0.019	1.816PheIle: 1.816 ± 0.033	1.096PheLys: 1.096 ± 0.024	3.535PheLeu: 3.535 ± 0.044	0.86PheMet: 0.86 ± 0.022	1.05PheAsn: 1.05 ± 0.023	1.646PhePro: 1.646 ± 0.029	1.087PheGln: 1.087 ± 0.027	2.348PheArg: 2.348 ± 0.032	2.444PheSer: 2.444 ± 0.032	1.934PheThr: 1.934 ± 0.029	3.082PheVal: 3.082 ± 0.045	0.582PheTrp: 0.582 ± 0.017	0.925PheTyr: 0.925 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.072GlyAla: 9.072 ± 0.079	0.801GlyCys: 0.801 ± 0.019	4.526GlyAsp: 4.526 ± 0.058	4.696GlyGlu: 4.696 ± 0.048	3.758GlyPhe: 3.758 ± 0.047	7.257GlyGly: 7.257 ± 0.105	1.984GlyHis: 1.984 ± 0.034	4.962GlyIle: 4.962 ± 0.049	3.832GlyLys: 3.832 ± 0.05	8.735GlyLeu: 8.735 ± 0.081	2.347GlyMet: 2.347 ± 0.038	2.355GlyAsn: 2.355 ± 0.044	3.393GlyPro: 3.393 ± 0.04	2.835GlyGln: 2.835 ± 0.04	5.816GlyArg: 5.816 ± 0.06	4.809GlySer: 4.809 ± 0.059	4.625GlyThr: 4.625 ± 0.053	6.047GlyVal: 6.047 ± 0.064	1.372GlyTrp: 1.372 ± 0.022	2.298GlyTyr: 2.298 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	2.293HisAla: 2.293 ± 0.031	0.248HisCys: 0.248 ± 0.012	1.282HisAsp: 1.282 ± 0.029	1.098HisGlu: 1.098 ± 0.025	0.922HisPhe: 0.922 ± 0.022	1.905HisGly: 1.905 ± 0.03	0.593HisHis: 0.593 ± 0.02	0.991HisIle: 0.991 ± 0.023	0.557HisLys: 0.557 ± 0.016	1.998HisLeu: 1.998 ± 0.034	0.509HisMet: 0.509 ± 0.014	0.467HisAsn: 0.467 ± 0.014	1.28HisPro: 1.28 ± 0.028	0.631HisGln: 0.631 ± 0.017	1.428HisArg: 1.428 ± 0.029	0.993HisSer: 0.993 ± 0.026	0.817HisThr: 0.817 ± 0.02	1.522HisVal: 1.522 ± 0.026	0.351HisTrp: 0.351 ± 0.011	0.572HisTyr: 0.572 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	7.653IleAla: 7.653 ± 0.068	0.503IleCys: 0.503 ± 0.015	3.831IleAsp: 3.831 ± 0.046	3.643IleGlu: 3.643 ± 0.042	1.849IlePhe: 1.849 ± 0.03	5.27IleGly: 5.27 ± 0.062	1.004IleHis: 1.004 ± 0.023	2.511IleIle: 2.511 ± 0.039	1.628IleLys: 1.628 ± 0.026	4.551IleLeu: 4.551 ± 0.056	1.087IleMet: 1.087 ± 0.024	1.491IleAsn: 1.491 ± 0.029	2.324IlePro: 2.324 ± 0.033	1.207IleGln: 1.207 ± 0.026	3.395IleArg: 3.395 ± 0.041	3.162IleSer: 3.162 ± 0.045	2.624IleThr: 2.624 ± 0.037	4.751IleVal: 4.751 ± 0.056	0.618IleTrp: 0.618 ± 0.017	1.183IleTyr: 1.183 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.91LysAla: 4.91 ± 0.065	0.188LysCys: 0.188 ± 0.009	1.951LysAsp: 1.951 ± 0.034	1.724LysGlu: 1.724 ± 0.034	1.008LysPhe: 1.008 ± 0.024	2.893LysGly: 2.893 ± 0.039	0.639LysHis: 0.639 ± 0.019	1.949LysIle: 1.949 ± 0.03	1.588LysLys: 1.588 ± 0.038	3.687LysLeu: 3.687 ± 0.048	0.898LysMet: 0.898 ± 0.024	1.03LysAsn: 1.03 ± 0.023	2.411LysPro: 2.411 ± 0.038	1.144LysGln: 1.144 ± 0.024	2.461LysArg: 2.461 ± 0.036	2.177LysSer: 2.177 ± 0.032	2.218LysThr: 2.218 ± 0.039	2.764LysVal: 2.764 ± 0.041	0.468LysTrp: 0.468 ± 0.017	0.691LysTyr: 0.691 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.357LeuAla: 13.357 ± 0.116	0.869LeuCys: 0.869 ± 0.022	5.939LeuAsp: 5.939 ± 0.063	5.122LeuGlu: 5.122 ± 0.059	3.695LeuPhe: 3.695 ± 0.041	8.269LeuGly: 8.269 ± 0.054	1.79LeuHis: 1.79 ± 0.031	5.083LeuIle: 5.083 ± 0.069	3.897LeuLys: 3.897 ± 0.046	9.238LeuLeu: 9.238 ± 0.095	2.274LeuMet: 2.274 ± 0.034	2.516LeuAsn: 2.516 ± 0.036	5.334LeuPro: 5.334 ± 0.054	2.73LeuGln: 2.73 ± 0.039	6.365LeuArg: 6.365 ± 0.065	6.555LeuSer: 6.555 ± 0.063	5.255LeuThr: 5.255 ± 0.049	7.612LeuVal: 7.612 ± 0.07	1.138LeuTrp: 1.138 ± 0.026	2.07LeuTyr: 2.07 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	3.209MetAla: 3.209 ± 0.044	0.158MetCys: 0.158 ± 0.01	1.135MetAsp: 1.135 ± 0.02	1.086MetGlu: 1.086 ± 0.024	0.752MetPhe: 0.752 ± 0.02	1.696MetGly: 1.696 ± 0.028	0.478MetHis: 0.478 ± 0.014	1.4MetIle: 1.4 ± 0.029	1.091MetLys: 1.091 ± 0.024	2.607MetLeu: 2.607 ± 0.036	0.674MetMet: 0.674 ± 0.019	0.831MetAsn: 0.831 ± 0.02	1.513MetPro: 1.513 ± 0.028	0.86MetGln: 0.86 ± 0.02	1.804MetArg: 1.804 ± 0.034	1.638MetSer: 1.638 ± 0.027	1.829MetThr: 1.829 ± 0.028	1.807MetVal: 1.807 ± 0.03	0.221MetTrp: 0.221 ± 0.01	0.297MetTyr: 0.297 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.25AsnAla: 3.25 ± 0.045	0.252AsnCys: 0.252 ± 0.01	1.512AsnAsp: 1.512 ± 0.038	1.32AsnGlu: 1.32 ± 0.025	1.083AsnPhe: 1.083 ± 0.023	2.575AsnGly: 2.575 ± 0.038	0.542AsnHis: 0.542 ± 0.015	1.44AsnIle: 1.44 ± 0.03	0.775AsnLys: 0.775 ± 0.021	2.591AsnLeu: 2.591 ± 0.034	0.659AsnMet: 0.659 ± 0.019	0.719AsnAsn: 0.719 ± 0.019	1.888AsnPro: 1.888 ± 0.03	0.78AsnGln: 0.78 ± 0.018	1.787AsnArg: 1.787 ± 0.027	1.347AsnSer: 1.347 ± 0.029	1.304AsnThr: 1.304 ± 0.026	2.022AsnVal: 2.022 ± 0.036	0.452AsnTrp: 0.452 ± 0.015	0.713AsnTyr: 0.713 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.241ProAla: 6.241 ± 0.074	0.299ProCys: 0.299 ± 0.013	3.463ProAsp: 3.463 ± 0.048	3.444ProGlu: 3.444 ± 0.049	2.017ProPhe: 2.017 ± 0.034	4.32ProGly: 4.32 ± 0.051	1.028ProHis: 1.028 ± 0.024	2.306ProIle: 2.306 ± 0.033	1.887ProLys: 1.887 ± 0.035	4.638ProLeu: 4.638 ± 0.05	1.131ProMet: 1.131 ± 0.025	1.358ProAsn: 1.358 ± 0.025	2.334ProPro: 2.334 ± 0.042	1.598ProGln: 1.598 ± 0.03	2.75ProArg: 2.75 ± 0.036	2.749ProSer: 2.749 ± 0.04	2.412ProThr: 2.412 ± 0.029	4.157ProVal: 4.157 ± 0.057	0.716ProTrp: 0.716 ± 0.02	1.218ProTyr: 1.218 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.998GlnAla: 3.998 ± 0.048	0.205GlnCys: 0.205 ± 0.01	1.454GlnAsp: 1.454 ± 0.028	1.448GlnGlu: 1.448 ± 0.028	1.093GlnPhe: 1.093 ± 0.023	2.236GlnGly: 2.236 ± 0.034	0.63GlnHis: 0.63 ± 0.017	1.764GlnIle: 1.764 ± 0.033	1.253GlnLys: 1.253 ± 0.027	2.861GlnLeu: 2.861 ± 0.044	0.873GlnMet: 0.873 ± 0.019	0.874GlnAsn: 0.874 ± 0.021	1.729GlnPro: 1.729 ± 0.03	1.181GlnGln: 1.181 ± 0.025	2.34GlnArg: 2.34 ± 0.035	1.763GlnSer: 1.763 ± 0.028	1.657GlnThr: 1.657 ± 0.028	2.081GlnVal: 2.081 ± 0.035	0.393GlnTrp: 0.393 ± 0.013	0.589GlnTyr: 0.589 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	7.308ArgAla: 7.308 ± 0.081	0.49ArgCys: 0.49 ± 0.015	3.908ArgAsp: 3.908 ± 0.048	3.815ArgGlu: 3.815 ± 0.045	2.934ArgPhe: 2.934 ± 0.039	4.472ArgGly: 4.472 ± 0.045	1.741ArgHis: 1.741 ± 0.034	4.024ArgIle: 4.024 ± 0.043	2.525ArgLys: 2.525 ± 0.04	7.685ArgLeu: 7.685 ± 0.084	1.791ArgMet: 1.791 ± 0.029	1.965ArgAsn: 1.965 ± 0.031	3.38ArgPro: 3.38 ± 0.048	2.657ArgGln: 2.657 ± 0.041	5.409ArgArg: 5.409 ± 0.063	3.822ArgSer: 3.822 ± 0.043	3.365ArgThr: 3.365 ± 0.048	4.317ArgVal: 4.317 ± 0.045	0.94ArgTrp: 0.94 ± 0.023	1.66ArgTyr: 1.66 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	6.461SerAla: 6.461 ± 0.058	0.42SerCys: 0.42 ± 0.013	3.137SerAsp: 3.137 ± 0.037	2.826SerGlu: 2.826 ± 0.039	2.434SerPhe: 2.434 ± 0.038	5.794SerGly: 5.794 ± 0.059	1.15SerHis: 1.15 ± 0.024	3.058SerIle: 3.058 ± 0.045	1.814SerLys: 1.814 ± 0.031	5.554SerLeu: 5.554 ± 0.055	1.404SerMet: 1.404 ± 0.03	1.457SerAsn: 1.457 ± 0.028	2.832SerPro: 2.832 ± 0.038	1.609SerGln: 1.609 ± 0.025	3.642SerArg: 3.642 ± 0.047	3.035SerSer: 3.035 ± 0.049	2.774SerThr: 2.774 ± 0.041	4.311SerVal: 4.311 ± 0.054	0.803SerTrp: 0.803 ± 0.02	1.293SerTyr: 1.293 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	6.152ThrAla: 6.152 ± 0.057	0.422ThrCys: 0.422 ± 0.016	2.789ThrAsp: 2.789 ± 0.045	2.645ThrGlu: 2.645 ± 0.037	2.089ThrPhe: 2.089 ± 0.033	5.069ThrGly: 5.069 ± 0.054	0.964ThrHis: 0.964 ± 0.022	3.166ThrIle: 3.166 ± 0.045	1.661ThrLys: 1.661 ± 0.029	5.538ThrLeu: 5.538 ± 0.054	1.301ThrMet: 1.301 ± 0.027	1.339ThrAsn: 1.339 ± 0.029	2.961ThrPro: 2.961 ± 0.042	1.305ThrGln: 1.305 ± 0.023	3.089ThrArg: 3.089 ± 0.038	2.975ThrSer: 2.975 ± 0.038	2.83ThrThr: 2.83 ± 0.051	4.424ThrVal: 4.424 ± 0.05	0.642ThrTrp: 0.642 ± 0.018	1.155ThrTyr: 1.155 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	9.478ValAla: 9.478 ± 0.074	0.653ValCys: 0.653 ± 0.018	4.305ValAsp: 4.305 ± 0.049	4.482ValGlu: 4.482 ± 0.05	2.948ValPhe: 2.948 ± 0.043	5.797ValGly: 5.797 ± 0.061	1.397ValHis: 1.397 ± 0.033	3.949ValIle: 3.949 ± 0.054	2.594ValLys: 2.594 ± 0.036	7.393ValLeu: 7.393 ± 0.072	1.807ValMet: 1.807 ± 0.029	2.036ValAsn: 2.036 ± 0.04	3.666ValPro: 3.666 ± 0.047	1.948ValGln: 1.948 ± 0.033	4.828ValArg: 4.828 ± 0.051	4.589ValSer: 4.589 ± 0.053	4.439ValThr: 4.439 ± 0.053	6.081ValVal: 6.081 ± 0.062	0.895ValTrp: 0.895 ± 0.021	1.46ValTyr: 1.46 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.245TrpAla: 1.245 ± 0.027	0.141TrpCys: 0.141 ± 0.008	0.609TrpAsp: 0.609 ± 0.019	0.526TrpGlu: 0.526 ± 0.016	0.548TrpPhe: 0.548 ± 0.017	0.87TrpGly: 0.87 ± 0.019	0.331TrpHis: 0.331 ± 0.013	0.683TrpIle: 0.683 ± 0.02	0.534TrpLys: 0.534 ± 0.016	1.685TrpLeu: 1.685 ± 0.028	0.356TrpMet: 0.356 ± 0.014	0.487TrpAsn: 0.487 ± 0.014	0.717TrpPro: 0.717 ± 0.019	0.601TrpGln: 0.601 ± 0.019	1.088TrpArg: 1.088 ± 0.023	0.864TrpSer: 0.864 ± 0.022	0.764TrpThr: 0.764 ± 0.019	0.829TrpVal: 0.829 ± 0.017	0.22TrpTrp: 0.22 ± 0.009	0.315TrpTyr: 0.315 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.515TyrAla: 2.515 ± 0.034	0.243TyrCys: 0.243 ± 0.012	1.442TyrAsp: 1.442 ± 0.028	1.209TyrGlu: 1.209 ± 0.027	0.956TyrPhe: 0.956 ± 0.022	2.085TyrGly: 2.085 ± 0.034	0.48TyrHis: 0.48 ± 0.016	0.914TyrIle: 0.914 ± 0.022	0.659TyrLys: 0.659 ± 0.021	2.214TyrLeu: 2.214 ± 0.031	0.442TyrMet: 0.442 ± 0.017	0.594TyrAsn: 0.594 ± 0.018	1.09TyrPro: 1.09 ± 0.025	0.732TyrGln: 0.732 ± 0.02	1.744TyrArg: 1.744 ± 0.03	1.263TyrSer: 1.263 ± 0.026	1.121TyrThr: 1.121 ± 0.022	1.682TyrVal: 1.682 ± 0.025	0.343TyrTrp: 0.343 ± 0.014	0.586TyrTyr: 0.586 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7083 proteins (2092589 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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