Amino acid dipepetide frequency for Mariniradius saccharolyticus AK6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.718AlaAla: 5.718 ± 0.094	0.604AlaCys: 0.604 ± 0.023	3.814AlaAsp: 3.814 ± 0.055	4.704AlaGlu: 4.704 ± 0.055	3.871AlaPhe: 3.871 ± 0.055	5.429AlaGly: 5.429 ± 0.076	1.247AlaHis: 1.247 ± 0.031	4.945AlaIle: 4.945 ± 0.074	4.787AlaLys: 4.787 ± 0.067	6.758AlaLeu: 6.758 ± 0.067	1.873AlaMet: 1.873 ± 0.041	3.301AlaAsn: 3.301 ± 0.049	2.426AlaPro: 2.426 ± 0.049	2.702AlaGln: 2.702 ± 0.045	2.586AlaArg: 2.586 ± 0.046	4.298AlaSer: 4.298 ± 0.059	3.346AlaThr: 3.346 ± 0.058	4.725AlaVal: 4.725 ± 0.063	0.988AlaTrp: 0.988 ± 0.027	2.636AlaTyr: 2.636 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.467CysAla: 0.467 ± 0.02	0.102CysCys: 0.102 ± 0.009	0.362CysAsp: 0.362 ± 0.014	0.403CysGlu: 0.403 ± 0.021	0.398CysPhe: 0.398 ± 0.022	0.589CysGly: 0.589 ± 0.024	0.205CysHis: 0.205 ± 0.015	0.454CysIle: 0.454 ± 0.017	0.35CysLys: 0.35 ± 0.018	0.664CysLeu: 0.664 ± 0.025	0.139CysMet: 0.139 ± 0.011	0.271CysAsn: 0.271 ± 0.014	0.322CysPro: 0.322 ± 0.019	0.269CysGln: 0.269 ± 0.014	0.288CysArg: 0.288 ± 0.013	0.442CysSer: 0.442 ± 0.018	0.349CysThr: 0.349 ± 0.016	0.41CysVal: 0.41 ± 0.019	0.082CysTrp: 0.082 ± 0.008	0.224CysTyr: 0.224 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.591AspAla: 3.591 ± 0.06	0.375AspCys: 0.375 ± 0.017	2.203AspAsp: 2.203 ± 0.042	3.327AspGlu: 3.327 ± 0.051	3.806AspPhe: 3.806 ± 0.051	4.003AspGly: 4.003 ± 0.063	0.992AspHis: 0.992 ± 0.026	3.737AspIle: 3.737 ± 0.055	3.236AspLys: 3.236 ± 0.057	5.653AspLeu: 5.653 ± 0.077	1.274AspMet: 1.274 ± 0.032	2.174AspAsn: 2.174 ± 0.04	2.651AspPro: 2.651 ± 0.048	1.948AspGln: 1.948 ± 0.033	2.607AspArg: 2.607 ± 0.045	2.873AspSer: 2.873 ± 0.052	2.297AspThr: 2.297 ± 0.039	3.047AspVal: 3.047 ± 0.046	0.926AspTrp: 0.926 ± 0.026	2.284AspTyr: 2.284 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	4.716GluAla: 4.716 ± 0.067	0.29GluCys: 0.29 ± 0.016	3.238GluAsp: 3.238 ± 0.048	4.72GluGlu: 4.72 ± 0.077	3.163GluPhe: 3.163 ± 0.048	4.377GluGly: 4.377 ± 0.046	1.074GluHis: 1.074 ± 0.03	5.371GluIle: 5.371 ± 0.071	5.835GluLys: 5.835 ± 0.088	6.023GluLeu: 6.023 ± 0.075	1.866GluMet: 1.866 ± 0.037	3.824GluAsn: 3.824 ± 0.049	1.958GluPro: 1.958 ± 0.038	2.191GluGln: 2.191 ± 0.044	3.06GluArg: 3.06 ± 0.053	3.724GluSer: 3.724 ± 0.053	3.199GluThr: 3.199 ± 0.048	4.499GluVal: 4.499 ± 0.059	0.838GluTrp: 0.838 ± 0.027	2.107GluTyr: 2.107 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.662PheAla: 3.662 ± 0.055	0.453PheCys: 0.453 ± 0.021	3.326PheAsp: 3.326 ± 0.047	3.771PheGlu: 3.771 ± 0.057	3.293PhePhe: 3.293 ± 0.057	4.381PheGly: 4.381 ± 0.064	1.08PheHis: 1.08 ± 0.027	2.963PheIle: 2.963 ± 0.05	2.792PheLys: 2.792 ± 0.043	5.516PheLeu: 5.516 ± 0.07	1.13PheMet: 1.13 ± 0.029	2.473PheAsn: 2.473 ± 0.049	2.313PhePro: 2.313 ± 0.041	2.119PheGln: 2.119 ± 0.038	2.559PheArg: 2.559 ± 0.047	4.254PheSer: 4.254 ± 0.059	2.748PheThr: 2.748 ± 0.044	3.548PheVal: 3.548 ± 0.05	0.828PheTrp: 0.828 ± 0.032	1.93PheTyr: 1.93 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.541GlyAla: 4.541 ± 0.065	0.551GlyCys: 0.551 ± 0.03	3.508GlyAsp: 3.508 ± 0.057	4.305GlyGlu: 4.305 ± 0.063	4.423GlyPhe: 4.423 ± 0.063	5.243GlyGly: 5.243 ± 0.101	1.313GlyHis: 1.313 ± 0.036	5.793GlyIle: 5.793 ± 0.073	5.766GlyLys: 5.766 ± 0.061	7.081GlyLeu: 7.081 ± 0.085	2.116GlyMet: 2.116 ± 0.044	3.679GlyAsn: 3.679 ± 0.059	2.132GlyPro: 2.132 ± 0.038	2.598GlyGln: 2.598 ± 0.044	3.119GlyArg: 3.119 ± 0.05	4.366GlySer: 4.366 ± 0.063	4.078GlyThr: 4.078 ± 0.065	4.513GlyVal: 4.513 ± 0.061	1.017GlyTrp: 1.017 ± 0.031	2.878GlyTyr: 2.878 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.306HisAla: 1.306 ± 0.029	0.187HisCys: 0.187 ± 0.013	0.861HisAsp: 0.861 ± 0.025	1.031HisGlu: 1.031 ± 0.031	1.293HisPhe: 1.293 ± 0.03	1.381HisGly: 1.381 ± 0.036	0.556HisHis: 0.556 ± 0.022	1.27HisIle: 1.27 ± 0.03	0.868HisLys: 0.868 ± 0.025	2.034HisLeu: 2.034 ± 0.039	0.436HisMet: 0.436 ± 0.017	0.648HisAsn: 0.648 ± 0.022	1.194HisPro: 1.194 ± 0.032	0.841HisGln: 0.841 ± 0.026	0.886HisArg: 0.886 ± 0.029	1.082HisSer: 1.082 ± 0.025	0.861HisThr: 0.861 ± 0.026	1.122HisVal: 1.122 ± 0.032	0.309HisTrp: 0.309 ± 0.018	0.79HisTyr: 0.79 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.166IleAla: 5.166 ± 0.059	0.577IleCys: 0.577 ± 0.022	3.848IleAsp: 3.848 ± 0.052	4.42IleGlu: 4.42 ± 0.07	3.392IlePhe: 3.392 ± 0.056	5.151IleGly: 5.151 ± 0.064	1.502IleHis: 1.502 ± 0.034	4.172IleIle: 4.172 ± 0.067	4.103IleLys: 4.103 ± 0.051	6.831IleLeu: 6.831 ± 0.071	1.327IleMet: 1.327 ± 0.035	3.248IleAsn: 3.248 ± 0.058	3.492IlePro: 3.492 ± 0.053	2.906IleGln: 2.906 ± 0.049	3.355IleArg: 3.355 ± 0.051	5.082IleSer: 5.082 ± 0.064	3.427IleThr: 3.427 ± 0.058	4.129IleVal: 4.129 ± 0.058	0.873IleTrp: 0.873 ± 0.027	2.279IleTyr: 2.279 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	4.754LysAla: 4.754 ± 0.077	0.279LysCys: 0.279 ± 0.016	3.671LysAsp: 3.671 ± 0.056	4.839LysGlu: 4.839 ± 0.06	2.605LysPhe: 2.605 ± 0.043	4.555LysGly: 4.555 ± 0.059	1.086LysHis: 1.086 ± 0.032	4.901LysIle: 4.901 ± 0.074	5.038LysLys: 5.038 ± 0.08	5.65LysLeu: 5.65 ± 0.067	1.934LysMet: 1.934 ± 0.042	3.559LysAsn: 3.559 ± 0.061	2.709LysPro: 2.709 ± 0.043	2.047LysGln: 2.047 ± 0.036	2.793LysArg: 2.793 ± 0.048	4.291LysSer: 4.291 ± 0.052	3.651LysThr: 3.651 ± 0.056	4.38LysVal: 4.38 ± 0.054	0.828LysTrp: 0.828 ± 0.022	2.304LysTyr: 2.304 ± 0.042	0.0LysXaa: 0.0 ± 0.0
Leu	7.526LeuAla: 7.526 ± 0.082	0.636LeuCys: 0.636 ± 0.021	5.517LeuAsp: 5.517 ± 0.063	6.893LeuGlu: 6.893 ± 0.074	5.026LeuPhe: 5.026 ± 0.061	7.298LeuGly: 7.298 ± 0.09	1.719LeuHis: 1.719 ± 0.034	6.244LeuIle: 6.244 ± 0.083	6.165LeuLys: 6.165 ± 0.078	9.272LeuLeu: 9.272 ± 0.111	2.397LeuMet: 2.397 ± 0.045	4.251LeuAsn: 4.251 ± 0.061	4.327LeuPro: 4.327 ± 0.057	3.584LeuGln: 3.584 ± 0.052	4.305LeuArg: 4.305 ± 0.054	6.576LeuSer: 6.576 ± 0.084	4.841LeuThr: 4.841 ± 0.057	6.656LeuVal: 6.656 ± 0.072	1.038LeuTrp: 1.038 ± 0.031	2.95LeuTyr: 2.95 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.089MetAla: 2.089 ± 0.04	0.115MetCys: 0.115 ± 0.01	1.507MetAsp: 1.507 ± 0.035	1.779MetGlu: 1.779 ± 0.036	0.898MetPhe: 0.898 ± 0.027	1.958MetGly: 1.958 ± 0.038	0.475MetHis: 0.475 ± 0.018	1.579MetIle: 1.579 ± 0.035	1.96MetLys: 1.96 ± 0.039	2.282MetLeu: 2.282 ± 0.044	0.703MetMet: 0.703 ± 0.023	1.144MetAsn: 1.144 ± 0.025	1.144MetPro: 1.144 ± 0.031	0.903MetGln: 0.903 ± 0.024	1.16MetArg: 1.16 ± 0.026	1.352MetSer: 1.352 ± 0.031	1.243MetThr: 1.243 ± 0.035	1.902MetVal: 1.902 ± 0.043	0.209MetTrp: 0.209 ± 0.013	0.68MetTyr: 0.68 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.249AsnAla: 3.249 ± 0.059	0.32AsnCys: 0.32 ± 0.016	2.14AsnAsp: 2.14 ± 0.045	2.589AsnGlu: 2.589 ± 0.055	2.719AsnPhe: 2.719 ± 0.047	3.575AsnGly: 3.575 ± 0.069	0.937AsnHis: 0.937 ± 0.027	3.198AsnIle: 3.198 ± 0.059	2.504AsnLys: 2.504 ± 0.044	5.045AsnLeu: 5.045 ± 0.07	1.117AsnMet: 1.117 ± 0.029	2.237AsnAsn: 2.237 ± 0.05	3.143AsnPro: 3.143 ± 0.051	2.139AsnGln: 2.139 ± 0.044	2.419AsnArg: 2.419 ± 0.045	2.893AsnSer: 2.893 ± 0.044	2.464AsnThr: 2.464 ± 0.052	2.795AsnVal: 2.795 ± 0.05	0.779AsnTrp: 0.779 ± 0.022	1.852AsnTyr: 1.852 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	3.04ProAla: 3.04 ± 0.052	0.226ProCys: 0.226 ± 0.012	2.646ProAsp: 2.646 ± 0.044	3.416ProGlu: 3.416 ± 0.051	2.301ProPhe: 2.301 ± 0.04	2.985ProGly: 2.985 ± 0.056	0.769ProHis: 0.769 ± 0.025	2.91ProIle: 2.91 ± 0.048	2.738ProLys: 2.738 ± 0.046	3.58ProLeu: 3.58 ± 0.051	1.029ProMet: 1.029 ± 0.029	2.288ProAsn: 2.288 ± 0.049	1.178ProPro: 1.178 ± 0.034	1.41ProGln: 1.41 ± 0.033	1.441ProArg: 1.441 ± 0.034	2.668ProSer: 2.668 ± 0.05	2.148ProThr: 2.148 ± 0.044	2.988ProVal: 2.988 ± 0.045	0.504ProTrp: 0.504 ± 0.02	1.472ProTyr: 1.472 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.738GlnAla: 2.738 ± 0.047	0.151GlnCys: 0.151 ± 0.011	1.8GlnAsp: 1.8 ± 0.038	2.586GlnGlu: 2.586 ± 0.049	1.848GlnPhe: 1.848 ± 0.039	2.275GlnGly: 2.275 ± 0.045	0.655GlnHis: 0.655 ± 0.024	2.779GlnIle: 2.779 ± 0.039	2.706GlnLys: 2.706 ± 0.044	3.518GlnLeu: 3.518 ± 0.053	1.048GlnMet: 1.048 ± 0.024	1.936GlnAsn: 1.936 ± 0.039	1.41GlnPro: 1.41 ± 0.034	1.553GlnGln: 1.553 ± 0.035	1.686GlnArg: 1.686 ± 0.037	2.256GlnSer: 2.256 ± 0.036	2.02GlnThr: 2.02 ± 0.041	2.618GlnVal: 2.618 ± 0.042	0.47GlnTrp: 0.47 ± 0.018	1.302GlnTyr: 1.302 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	2.676ArgAla: 2.676 ± 0.048	0.221ArgCys: 0.221 ± 0.012	2.373ArgAsp: 2.373 ± 0.043	3.174ArgGlu: 3.174 ± 0.045	2.627ArgPhe: 2.627 ± 0.05	2.633ArgGly: 2.633 ± 0.045	0.874ArgHis: 0.874 ± 0.028	3.577ArgIle: 3.577 ± 0.051	3.189ArgLys: 3.189 ± 0.046	4.354ArgLeu: 4.354 ± 0.058	1.247ArgMet: 1.247 ± 0.027	2.343ArgAsn: 2.343 ± 0.041	1.708ArgPro: 1.708 ± 0.033	1.696ArgGln: 1.696 ± 0.034	1.988ArgArg: 1.988 ± 0.042	2.389ArgSer: 2.389 ± 0.042	2.19ArgThr: 2.19 ± 0.042	2.732ArgVal: 2.732 ± 0.049	0.581ArgTrp: 0.581 ± 0.02	1.787ArgTyr: 1.787 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.057SerAla: 4.057 ± 0.061	0.502SerCys: 0.502 ± 0.021	3.139SerAsp: 3.139 ± 0.052	3.876SerGlu: 3.876 ± 0.064	3.726SerPhe: 3.726 ± 0.06	4.962SerGly: 4.962 ± 0.058	1.194SerHis: 1.194 ± 0.03	4.543SerIle: 4.543 ± 0.058	4.099SerLys: 4.099 ± 0.058	6.474SerLeu: 6.474 ± 0.074	1.557SerMet: 1.557 ± 0.032	2.988SerAsn: 2.988 ± 0.053	2.724SerPro: 2.724 ± 0.049	2.369SerGln: 2.369 ± 0.041	2.708SerArg: 2.708 ± 0.039	3.647SerSer: 3.647 ± 0.056	3.102SerThr: 3.102 ± 0.051	3.836SerVal: 3.836 ± 0.06	0.82SerTrp: 0.82 ± 0.023	2.326SerTyr: 2.326 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	3.644ThrAla: 3.644 ± 0.053	0.327ThrCys: 0.327 ± 0.015	2.769ThrAsp: 2.769 ± 0.04	3.049ThrGlu: 3.049 ± 0.047	2.772ThrPhe: 2.772 ± 0.047	4.204ThrGly: 4.204 ± 0.07	0.976ThrHis: 0.976 ± 0.024	3.581ThrIle: 3.581 ± 0.063	2.926ThrLys: 2.926 ± 0.042	4.901ThrLeu: 4.901 ± 0.063	1.064ThrMet: 1.064 ± 0.032	2.327ThrAsn: 2.327 ± 0.049	2.285ThrPro: 2.285 ± 0.04	1.769ThrGln: 1.769 ± 0.033	1.919ThrArg: 1.919 ± 0.041	2.974ThrSer: 2.974 ± 0.05	2.527ThrThr: 2.527 ± 0.051	3.653ThrVal: 3.653 ± 0.067	0.79ThrTrp: 0.79 ± 0.029	1.969ThrTyr: 1.969 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	4.571ValAla: 4.571 ± 0.059	0.503ValCys: 0.503 ± 0.02	3.606ValAsp: 3.606 ± 0.054	4.08ValGlu: 4.08 ± 0.057	3.867ValPhe: 3.867 ± 0.059	4.49ValGly: 4.49 ± 0.061	1.167ValHis: 1.167 ± 0.03	4.302ValIle: 4.302 ± 0.059	4.009ValLys: 4.009 ± 0.056	6.419ValLeu: 6.419 ± 0.082	1.634ValMet: 1.634 ± 0.036	3.165ValAsn: 3.165 ± 0.046	2.639ValPro: 2.639 ± 0.05	2.123ValGln: 2.123 ± 0.038	2.885ValArg: 2.885 ± 0.049	4.467ValSer: 4.467 ± 0.06	3.394ValThr: 3.394 ± 0.064	4.357ValVal: 4.357 ± 0.066	0.826ValTrp: 0.826 ± 0.026	2.273ValTyr: 2.273 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.836TrpAla: 0.836 ± 0.023	0.091TrpCys: 0.091 ± 0.008	0.783TrpAsp: 0.783 ± 0.026	0.968TrpGlu: 0.968 ± 0.026	0.617TrpPhe: 0.617 ± 0.023	0.92TrpGly: 0.92 ± 0.03	0.282TrpHis: 0.282 ± 0.015	0.959TrpIle: 0.959 ± 0.029	0.938TrpLys: 0.938 ± 0.029	1.26TrpLeu: 1.26 ± 0.032	0.463TrpMet: 0.463 ± 0.018	0.682TrpAsn: 0.682 ± 0.022	0.392TrpPro: 0.392 ± 0.02	0.513TrpGln: 0.513 ± 0.019	0.629TrpArg: 0.629 ± 0.021	0.803TrpSer: 0.803 ± 0.026	0.717TrpThr: 0.717 ± 0.024	0.909TrpVal: 0.909 ± 0.026	0.225TrpTrp: 0.225 ± 0.012	0.488TrpTyr: 0.488 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.412TyrAla: 2.412 ± 0.048	0.279TyrCys: 0.279 ± 0.015	1.892TyrAsp: 1.892 ± 0.039	2.144TyrGlu: 2.144 ± 0.037	2.494TyrPhe: 2.494 ± 0.045	2.611TyrGly: 2.611 ± 0.042	0.852TyrHis: 0.852 ± 0.025	2.003TyrIle: 2.003 ± 0.043	1.867TyrLys: 1.867 ± 0.037	3.907TyrLeu: 3.907 ± 0.062	0.727TyrMet: 0.727 ± 0.023	1.575TyrAsn: 1.575 ± 0.041	1.589TyrPro: 1.589 ± 0.034	1.673TyrGln: 1.673 ± 0.035	1.966TyrArg: 1.966 ± 0.04	2.213TyrSer: 2.213 ± 0.038	1.822TyrThr: 1.822 ± 0.044	1.96TyrVal: 1.96 ± 0.034	0.544TyrTrp: 0.544 ± 0.019	1.39TyrTyr: 1.39 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4633 proteins (1435942 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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