Amino acid dipepetide frequency for Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74) (Escherichia blattae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.046AlaAla: 11.046 ± 0.145	1.361AlaCys: 1.361 ± 0.041	4.982AlaAsp: 4.982 ± 0.066	5.479AlaGlu: 5.479 ± 0.092	3.55AlaPhe: 3.55 ± 0.059	8.802AlaGly: 8.802 ± 0.117	1.957AlaHis: 1.957 ± 0.042	5.809AlaIle: 5.809 ± 0.072	3.015AlaLys: 3.015 ± 0.06	12.728AlaLeu: 12.728 ± 0.11	3.069AlaMet: 3.069 ± 0.053	2.694AlaAsn: 2.694 ± 0.056	4.206AlaPro: 4.206 ± 0.067	4.331AlaGln: 4.331 ± 0.069	7.358AlaArg: 7.358 ± 0.087	5.813AlaSer: 5.813 ± 0.076	4.983AlaThr: 4.983 ± 0.075	6.79AlaVal: 6.79 ± 0.08	1.692AlaTrp: 1.692 ± 0.044	1.868AlaTyr: 1.868 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.134CysAla: 1.134 ± 0.03	0.212CysCys: 0.212 ± 0.013	0.631CysAsp: 0.631 ± 0.025	0.582CysGlu: 0.582 ± 0.023	0.455CysPhe: 0.455 ± 0.019	1.222CysGly: 1.222 ± 0.029	0.39CysHis: 0.39 ± 0.019	0.598CysIle: 0.598 ± 0.024	0.305CysLys: 0.305 ± 0.017	1.099CysLeu: 1.099 ± 0.032	0.242CysMet: 0.242 ± 0.015	0.322CysAsn: 0.322 ± 0.017	0.596CysPro: 0.596 ± 0.026	0.532CysGln: 0.532 ± 0.024	0.734CysArg: 0.734 ± 0.026	0.663CysSer: 0.663 ± 0.027	0.544CysThr: 0.544 ± 0.021	0.782CysVal: 0.782 ± 0.029	0.23CysTrp: 0.23 ± 0.014	0.367CysTyr: 0.367 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.142AspAla: 5.142 ± 0.07	0.485AspCys: 0.485 ± 0.019	3.011AspAsp: 3.011 ± 0.078	3.161AspGlu: 3.161 ± 0.056	2.004AspPhe: 2.004 ± 0.043	3.723AspGly: 3.723 ± 0.066	1.02AspHis: 1.02 ± 0.03	3.5AspIle: 3.5 ± 0.051	2.325AspLys: 2.325 ± 0.047	4.593AspLeu: 4.593 ± 0.066	1.368AspMet: 1.368 ± 0.036	2.268AspAsn: 2.268 ± 0.047	2.48AspPro: 2.48 ± 0.048	1.784AspGln: 1.784 ± 0.038	2.63AspArg: 2.63 ± 0.05	2.713AspSer: 2.713 ± 0.051	2.835AspThr: 2.835 ± 0.05	3.624AspVal: 3.624 ± 0.062	0.81AspTrp: 0.81 ± 0.028	1.793AspTyr: 1.793 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.117GluAla: 5.117 ± 0.065	0.483GluCys: 0.483 ± 0.021	2.251GluAsp: 2.251 ± 0.047	2.923GluGlu: 2.923 ± 0.064	1.654GluPhe: 1.654 ± 0.043	3.383GluGly: 3.383 ± 0.05	1.46GluHis: 1.46 ± 0.037	3.058GluIle: 3.058 ± 0.056	2.827GluLys: 2.827 ± 0.06	5.544GluLeu: 5.544 ± 0.079	1.648GluMet: 1.648 ± 0.033	2.154GluAsn: 2.154 ± 0.044	2.107GluPro: 2.107 ± 0.046	3.446GluGln: 3.446 ± 0.063	3.485GluArg: 3.485 ± 0.059	2.829GluSer: 2.829 ± 0.045	2.698GluThr: 2.698 ± 0.048	3.556GluVal: 3.556 ± 0.073	0.733GluTrp: 0.733 ± 0.027	1.464GluTyr: 1.464 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.597PheAla: 3.597 ± 0.06	0.575PheCys: 0.575 ± 0.023	2.235PheAsp: 2.235 ± 0.048	1.625PheGlu: 1.625 ± 0.037	1.602PhePhe: 1.602 ± 0.042	3.134PheGly: 3.134 ± 0.061	0.785PheHis: 0.785 ± 0.024	2.498PheIle: 2.498 ± 0.048	1.093PheLys: 1.093 ± 0.031	3.329PheLeu: 3.329 ± 0.064	0.974PheMet: 0.974 ± 0.03	1.578PheAsn: 1.578 ± 0.032	1.535PhePro: 1.535 ± 0.036	0.987PheGln: 0.987 ± 0.032	1.997PheArg: 1.997 ± 0.037	3.074PheSer: 3.074 ± 0.055	2.433PheThr: 2.433 ± 0.049	2.34PheVal: 2.34 ± 0.053	0.622PheTrp: 0.622 ± 0.024	1.181PheTyr: 1.181 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	6.904GlyAla: 6.904 ± 0.084	1.091GlyCys: 1.091 ± 0.028	3.881GlyAsp: 3.881 ± 0.077	4.695GlyGlu: 4.695 ± 0.071	3.292GlyPhe: 3.292 ± 0.055	5.87GlyGly: 5.87 ± 0.092	1.867GlyHis: 1.867 ± 0.04	5.15GlyIle: 5.15 ± 0.074	3.767GlyLys: 3.767 ± 0.059	8.028GlyLeu: 8.028 ± 0.097	2.574GlyMet: 2.574 ± 0.049	2.775GlyAsn: 2.775 ± 0.069	2.376GlyPro: 2.376 ± 0.041	3.303GlyGln: 3.303 ± 0.06	4.214GlyArg: 4.214 ± 0.061	4.338GlySer: 4.338 ± 0.064	3.77GlyThr: 3.77 ± 0.056	6.034GlyVal: 6.034 ± 0.074	1.358GlyTrp: 1.358 ± 0.035	2.729GlyTyr: 2.729 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.933HisAla: 1.933 ± 0.043	0.35HisCys: 0.35 ± 0.019	1.157HisAsp: 1.157 ± 0.032	1.059HisGlu: 1.059 ± 0.028	1.08HisPhe: 1.08 ± 0.029	1.895HisGly: 1.895 ± 0.049	0.831HisHis: 0.831 ± 0.028	1.399HisIle: 1.399 ± 0.035	0.741HisLys: 0.741 ± 0.028	2.32HisLeu: 2.32 ± 0.044	0.611HisMet: 0.611 ± 0.022	0.942HisAsn: 0.942 ± 0.028	1.489HisPro: 1.489 ± 0.035	1.367HisGln: 1.367 ± 0.036	1.395HisArg: 1.395 ± 0.037	1.37HisSer: 1.37 ± 0.036	1.162HisThr: 1.162 ± 0.027	1.236HisVal: 1.236 ± 0.027	0.474HisTrp: 0.474 ± 0.022	0.932HisTyr: 0.932 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.392IleAla: 6.392 ± 0.087	0.717IleCys: 0.717 ± 0.026	3.289IleAsp: 3.289 ± 0.056	2.991IleGlu: 2.991 ± 0.053	1.994IlePhe: 1.994 ± 0.052	4.412IleGly: 4.412 ± 0.075	1.287IleHis: 1.287 ± 0.033	3.345IleIle: 3.345 ± 0.059	2.019IleLys: 2.019 ± 0.043	5.085IleLeu: 5.085 ± 0.074	1.294IleMet: 1.294 ± 0.034	2.431IleAsn: 2.431 ± 0.049	2.814IlePro: 2.814 ± 0.048	1.737IleGln: 1.737 ± 0.037	3.252IleArg: 3.252 ± 0.058	3.861IleSer: 3.861 ± 0.054	3.68IleThr: 3.68 ± 0.061	3.67IleVal: 3.67 ± 0.063	0.703IleTrp: 0.703 ± 0.024	1.54IleTyr: 1.54 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.789LysAla: 3.789 ± 0.08	0.268LysCys: 0.268 ± 0.017	1.86LysAsp: 1.86 ± 0.043	1.919LysGlu: 1.919 ± 0.048	1.028LysPhe: 1.028 ± 0.03	2.597LysGly: 2.597 ± 0.058	0.79LysHis: 0.79 ± 0.027	2.113LysIle: 2.113 ± 0.047	1.939LysLys: 1.939 ± 0.042	3.628LysLeu: 3.628 ± 0.064	1.104LysMet: 1.104 ± 0.033	1.574LysAsn: 1.574 ± 0.037	1.952LysPro: 1.952 ± 0.049	1.704LysGln: 1.704 ± 0.042	2.25LysArg: 2.25 ± 0.042	2.05LysSer: 2.05 ± 0.043	2.344LysThr: 2.344 ± 0.048	2.559LysVal: 2.559 ± 0.05	0.422LysTrp: 0.422 ± 0.02	1.088LysTyr: 1.088 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	12.371LeuAla: 12.371 ± 0.127	1.39LeuCys: 1.39 ± 0.038	5.511LeuAsp: 5.511 ± 0.073	5.373LeuGlu: 5.373 ± 0.071	4.252LeuPhe: 4.252 ± 0.066	7.613LeuGly: 7.613 ± 0.099	2.481LeuHis: 2.481 ± 0.044	5.615LeuIle: 5.615 ± 0.076	3.983LeuLys: 3.983 ± 0.067	12.363LeuLeu: 12.363 ± 0.164	2.906LeuMet: 2.906 ± 0.046	3.949LeuAsn: 3.949 ± 0.057	5.83LeuPro: 5.83 ± 0.077	3.924LeuGln: 3.924 ± 0.061	6.548LeuArg: 6.548 ± 0.079	7.409LeuSer: 7.409 ± 0.085	6.148LeuThr: 6.148 ± 0.068	7.423LeuVal: 7.423 ± 0.09	1.534LeuTrp: 1.534 ± 0.039	2.687LeuTyr: 2.687 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	3.144MetAla: 3.144 ± 0.049	0.214MetCys: 0.214 ± 0.012	1.256MetAsp: 1.256 ± 0.034	1.189MetGlu: 1.189 ± 0.03	0.854MetPhe: 0.854 ± 0.029	1.96MetGly: 1.96 ± 0.041	0.566MetHis: 0.566 ± 0.021	1.428MetIle: 1.428 ± 0.042	1.266MetLys: 1.266 ± 0.033	3.192MetLeu: 3.192 ± 0.052	0.884MetMet: 0.884 ± 0.025	1.034MetAsn: 1.034 ± 0.028	1.372MetPro: 1.372 ± 0.028	1.131MetGln: 1.131 ± 0.029	1.486MetArg: 1.486 ± 0.035	1.769MetSer: 1.769 ± 0.041	1.758MetThr: 1.758 ± 0.035	2.005MetVal: 2.005 ± 0.04	0.274MetTrp: 0.274 ± 0.015	0.541MetTyr: 0.541 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.216AsnAla: 3.216 ± 0.058	0.338AsnCys: 0.338 ± 0.016	1.744AsnAsp: 1.744 ± 0.045	1.552AsnGlu: 1.552 ± 0.038	1.161AsnPhe: 1.161 ± 0.033	2.939AsnGly: 2.939 ± 0.054	0.845AsnHis: 0.845 ± 0.029	2.246AsnIle: 2.246 ± 0.046	1.383AsnLys: 1.383 ± 0.037	3.339AsnLeu: 3.339 ± 0.059	0.901AsnMet: 0.901 ± 0.026	1.445AsnAsn: 1.445 ± 0.045	2.209AsnPro: 2.209 ± 0.051	1.693AsnGln: 1.693 ± 0.048	2.086AsnArg: 2.086 ± 0.044	1.9AsnSer: 1.9 ± 0.045	1.885AsnThr: 1.885 ± 0.043	2.279AsnVal: 2.279 ± 0.042	0.552AsnTrp: 0.552 ± 0.023	1.138AsnTyr: 1.138 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	5.336ProAla: 5.336 ± 0.078	0.442ProCys: 0.442 ± 0.019	2.984ProAsp: 2.984 ± 0.05	3.446ProGlu: 3.446 ± 0.051	1.806ProPhe: 1.806 ± 0.039	4.426ProGly: 4.426 ± 0.062	1.137ProHis: 1.137 ± 0.03	1.531ProIle: 1.531 ± 0.036	1.275ProLys: 1.275 ± 0.035	5.393ProLeu: 5.393 ± 0.07	1.041ProMet: 1.041 ± 0.029	1.062ProAsn: 1.062 ± 0.031	1.91ProPro: 1.91 ± 0.047	2.437ProGln: 2.437 ± 0.046	2.487ProArg: 2.487 ± 0.051	1.957ProSer: 1.957 ± 0.041	1.899ProThr: 1.899 ± 0.043	4.573ProVal: 4.573 ± 0.065	0.878ProTrp: 0.878 ± 0.029	1.192ProTyr: 1.192 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.029GlnAla: 5.029 ± 0.08	0.414GlnCys: 0.414 ± 0.021	1.815GlnAsp: 1.815 ± 0.038	2.138GlnGlu: 2.138 ± 0.046	1.441GlnPhe: 1.441 ± 0.034	3.262GlnGly: 3.262 ± 0.051	1.302GlnHis: 1.302 ± 0.033	2.317GlnIle: 2.317 ± 0.04	1.553GlnLys: 1.553 ± 0.042	5.134GlnLeu: 5.134 ± 0.078	1.232GlnMet: 1.232 ± 0.028	1.29GlnAsn: 1.29 ± 0.038	2.356GlnPro: 2.356 ± 0.056	3.528GlnGln: 3.528 ± 0.078	3.221GlnArg: 3.221 ± 0.056	2.127GlnSer: 2.127 ± 0.047	2.019GlnThr: 2.019 ± 0.043	3.07GlnVal: 3.07 ± 0.049	0.704GlnTrp: 0.704 ± 0.023	1.272GlnTyr: 1.272 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	5.385ArgAla: 5.385 ± 0.073	0.66ArgCys: 0.66 ± 0.025	3.294ArgAsp: 3.294 ± 0.052	4.01ArgGlu: 4.01 ± 0.062	2.597ArgPhe: 2.597 ± 0.049	3.902ArgGly: 3.902 ± 0.061	1.839ArgHis: 1.839 ± 0.04	3.581ArgIle: 3.581 ± 0.059	2.357ArgLys: 2.357 ± 0.051	6.884ArgLeu: 6.884 ± 0.09	1.654ArgMet: 1.654 ± 0.035	2.156ArgAsn: 2.156 ± 0.042	2.592ArgPro: 2.592 ± 0.047	3.682ArgGln: 3.682 ± 0.064	4.162ArgArg: 4.162 ± 0.071	2.871ArgSer: 2.871 ± 0.051	2.682ArgThr: 2.682 ± 0.051	4.035ArgVal: 4.035 ± 0.063	1.062ArgTrp: 1.062 ± 0.031	2.364ArgTyr: 2.364 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.141SerAla: 6.141 ± 0.077	0.65SerCys: 0.65 ± 0.026	3.054SerAsp: 3.054 ± 0.057	3.012SerGlu: 3.012 ± 0.057	2.091SerPhe: 2.091 ± 0.042	5.681SerGly: 5.681 ± 0.089	1.453SerHis: 1.453 ± 0.036	2.68SerIle: 2.68 ± 0.053	1.803SerLys: 1.803 ± 0.039	6.406SerLeu: 6.406 ± 0.08	1.408SerMet: 1.408 ± 0.033	1.693SerAsn: 1.693 ± 0.041	2.732SerPro: 2.732 ± 0.047	2.493SerGln: 2.493 ± 0.054	3.76SerArg: 3.76 ± 0.059	3.2SerSer: 3.2 ± 0.062	2.854SerThr: 2.854 ± 0.043	4.228SerVal: 4.228 ± 0.064	1.024SerTrp: 1.024 ± 0.034	1.569SerTyr: 1.569 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	5.009ThrAla: 5.009 ± 0.071	0.557ThrCys: 0.557 ± 0.021	2.615ThrAsp: 2.615 ± 0.057	2.392ThrGlu: 2.392 ± 0.052	1.876ThrPhe: 1.876 ± 0.041	5.148ThrGly: 5.148 ± 0.072	1.186ThrHis: 1.186 ± 0.034	2.827ThrIle: 2.827 ± 0.052	1.257ThrLys: 1.257 ± 0.034	7.243ThrLeu: 7.243 ± 0.081	1.161ThrMet: 1.161 ± 0.031	1.371ThrAsn: 1.371 ± 0.035	3.404ThrPro: 3.404 ± 0.056	1.847ThrGln: 1.847 ± 0.035	3.643ThrArg: 3.643 ± 0.054	2.814ThrSer: 2.814 ± 0.047	2.899ThrThr: 2.899 ± 0.05	3.75ThrVal: 3.75 ± 0.061	0.839ThrTrp: 0.839 ± 0.026	1.074ThrTyr: 1.074 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	7.415ValAla: 7.415 ± 0.09	0.82ValCys: 0.82 ± 0.027	3.604ValAsp: 3.604 ± 0.055	3.576ValGlu: 3.576 ± 0.061	2.558ValPhe: 2.558 ± 0.049	4.777ValGly: 4.777 ± 0.077	1.29ValHis: 1.29 ± 0.033	4.619ValIle: 4.619 ± 0.07	2.709ValLys: 2.709 ± 0.047	7.471ValLeu: 7.471 ± 0.078	2.174ValMet: 2.174 ± 0.046	2.681ValAsn: 2.681 ± 0.055	3.059ValPro: 3.059 ± 0.046	2.344ValGln: 2.344 ± 0.046	3.888ValArg: 3.888 ± 0.055	4.56ValSer: 4.56 ± 0.074	4.319ValThr: 4.319 ± 0.111	5.736ValVal: 5.736 ± 0.092	0.982ValTrp: 0.982 ± 0.027	1.688ValTyr: 1.688 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.071TrpAla: 1.071 ± 0.031	0.215TrpCys: 0.215 ± 0.015	0.608TrpAsp: 0.608 ± 0.025	0.589TrpGlu: 0.589 ± 0.022	0.73TrpPhe: 0.73 ± 0.027	1.016TrpGly: 1.016 ± 0.032	0.498TrpHis: 0.498 ± 0.02	0.733TrpIle: 0.733 ± 0.026	0.471TrpLys: 0.471 ± 0.021	2.402TrpLeu: 2.402 ± 0.055	0.452TrpMet: 0.452 ± 0.017	0.457TrpAsn: 0.457 ± 0.02	0.732TrpPro: 0.732 ± 0.024	1.28TrpGln: 1.28 ± 0.037	1.167TrpArg: 1.167 ± 0.034	0.923TrpSer: 0.923 ± 0.042	0.57TrpThr: 0.57 ± 0.024	1.005TrpVal: 1.005 ± 0.03	0.253TrpTrp: 0.253 ± 0.016	0.443TrpTyr: 0.443 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.363TyrAla: 2.363 ± 0.038	0.397TyrCys: 0.397 ± 0.018	1.487TyrAsp: 1.487 ± 0.037	1.108TyrGlu: 1.108 ± 0.031	1.171TyrPhe: 1.171 ± 0.034	2.254TyrGly: 2.254 ± 0.048	0.761TyrHis: 0.761 ± 0.025	1.467TyrIle: 1.467 ± 0.042	0.889TyrLys: 0.889 ± 0.03	3.128TyrLeu: 3.128 ± 0.051	0.627TyrMet: 0.627 ± 0.024	0.975TyrAsn: 0.975 ± 0.032	1.462TyrPro: 1.462 ± 0.036	1.676TyrGln: 1.676 ± 0.041	2.006TyrArg: 2.006 ± 0.044	1.689TyrSer: 1.689 ± 0.042	1.43TyrThr: 1.43 ± 0.035	1.574TyrVal: 1.574 ± 0.034	0.467TyrTrp: 0.467 ± 0.021	0.947TyrTyr: 0.947 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3870 proteins (1211296 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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