Amino acid dipepetide frequency for Motilibacter peucedani

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.519AlaAla: 24.519 ± 0.252	1.036AlaCys: 1.036 ± 0.033	8.064AlaAsp: 8.064 ± 0.086	7.973AlaGlu: 7.973 ± 0.104	3.383AlaPhe: 3.383 ± 0.051	14.22AlaGly: 14.22 ± 0.125	2.693AlaHis: 2.693 ± 0.044	2.932AlaIle: 2.932 ± 0.054	2.341AlaLys: 2.341 ± 0.056	16.43AlaLeu: 16.43 ± 0.166	2.385AlaMet: 2.385 ± 0.045	1.762AlaAsn: 1.762 ± 0.042	7.665AlaPro: 7.665 ± 0.11	4.055AlaGln: 4.055 ± 0.061	10.987AlaArg: 10.987 ± 0.111	7.74AlaSer: 7.74 ± 0.087	7.95AlaThr: 7.95 ± 0.093	14.215AlaVal: 14.215 ± 0.127	2.001AlaTrp: 2.001 ± 0.041	2.827AlaTyr: 2.827 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.905CysAla: 0.905 ± 0.028	0.085CysCys: 0.085 ± 0.008	0.451CysAsp: 0.451 ± 0.019	0.325CysGlu: 0.325 ± 0.016	0.188CysPhe: 0.188 ± 0.014	0.793CysGly: 0.793 ± 0.026	0.144CysHis: 0.144 ± 0.011	0.189CysIle: 0.189 ± 0.013	0.085CysLys: 0.085 ± 0.008	0.642CysLeu: 0.642 ± 0.025	0.09CysMet: 0.09 ± 0.009	0.099CysAsn: 0.099 ± 0.009	0.404CysPro: 0.404 ± 0.019	0.125CysGln: 0.125 ± 0.01	0.478CysArg: 0.478 ± 0.022	0.438CysSer: 0.438 ± 0.02	0.498CysThr: 0.498 ± 0.02	0.589CysVal: 0.589 ± 0.019	0.102CysTrp: 0.102 ± 0.01	0.143CysTyr: 0.143 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.568AspAla: 8.568 ± 0.083	0.316AspCys: 0.316 ± 0.018	4.228AspAsp: 4.228 ± 0.07	4.172AspGlu: 4.172 ± 0.06	1.365AspPhe: 1.365 ± 0.038	6.249AspGly: 6.249 ± 0.081	1.033AspHis: 1.033 ± 0.032	1.517AspIle: 1.517 ± 0.041	0.86AspLys: 0.86 ± 0.029	6.329AspLeu: 6.329 ± 0.078	0.651AspMet: 0.651 ± 0.023	0.783AspAsn: 0.783 ± 0.031	4.429AspPro: 4.429 ± 0.06	1.298AspGln: 1.298 ± 0.035	4.235AspArg: 4.235 ± 0.064	2.669AspSer: 2.669 ± 0.05	2.762AspThr: 2.762 ± 0.052	5.882AspVal: 5.882 ± 0.062	0.948AspTrp: 0.948 ± 0.027	1.262AspTyr: 1.262 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	7.125GluAla: 7.125 ± 0.095	0.275GluCys: 0.275 ± 0.014	2.505GluAsp: 2.505 ± 0.044	2.677GluGlu: 2.677 ± 0.059	1.237GluPhe: 1.237 ± 0.031	4.261GluGly: 4.261 ± 0.073	1.478GluHis: 1.478 ± 0.037	1.544GluIle: 1.544 ± 0.039	0.973GluLys: 0.973 ± 0.035	6.891GluLeu: 6.891 ± 0.095	0.711GluMet: 0.711 ± 0.026	0.647GluAsn: 0.647 ± 0.025	3.237GluPro: 3.237 ± 0.061	2.474GluGln: 2.474 ± 0.054	5.445GluArg: 5.445 ± 0.081	2.447GluSer: 2.447 ± 0.047	2.503GluThr: 2.503 ± 0.052	5.443GluVal: 5.443 ± 0.083	0.669GluTrp: 0.669 ± 0.022	0.629GluTyr: 0.629 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	3.574PheAla: 3.574 ± 0.059	0.217PheCys: 0.217 ± 0.014	1.906PheAsp: 1.906 ± 0.043	1.327PheGlu: 1.327 ± 0.031	0.845PhePhe: 0.845 ± 0.032	2.711PheGly: 2.711 ± 0.05	0.458PheHis: 0.458 ± 0.02	0.546PheIle: 0.546 ± 0.022	0.412PheLys: 0.412 ± 0.018	2.261PheLeu: 2.261 ± 0.051	0.282PheMet: 0.282 ± 0.015	0.495PheAsn: 0.495 ± 0.023	1.19PhePro: 1.19 ± 0.037	0.577PheGln: 0.577 ± 0.023	1.607PheArg: 1.607 ± 0.045	1.492PheSer: 1.492 ± 0.036	1.717PheThr: 1.717 ± 0.039	2.577PheVal: 2.577 ± 0.053	0.383PheTrp: 0.383 ± 0.018	0.554PheTyr: 0.554 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	12.386GlyAla: 12.386 ± 0.126	0.738GlyCys: 0.738 ± 0.023	5.08GlyAsp: 5.08 ± 0.065	4.719GlyGlu: 4.719 ± 0.058	2.827GlyPhe: 2.827 ± 0.05	8.75GlyGly: 8.75 ± 0.118	1.946GlyHis: 1.946 ± 0.036	3.056GlyIle: 3.056 ± 0.055	1.894GlyLys: 1.894 ± 0.045	9.729GlyLeu: 9.729 ± 0.109	1.706GlyMet: 1.706 ± 0.037	1.469GlyAsn: 1.469 ± 0.045	4.867GlyPro: 4.867 ± 0.07	2.39GlyGln: 2.39 ± 0.051	7.552GlyArg: 7.552 ± 0.1	6.371GlySer: 6.371 ± 0.096	6.421GlyThr: 6.421 ± 0.085	8.666GlyVal: 8.666 ± 0.088	1.82GlyTrp: 1.82 ± 0.043	2.157GlyTyr: 2.157 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.498HisAla: 2.498 ± 0.047	0.171HisCys: 0.171 ± 0.011	1.385HisAsp: 1.385 ± 0.033	1.198HisGlu: 1.198 ± 0.03	0.508HisPhe: 0.508 ± 0.019	2.136HisGly: 2.136 ± 0.049	0.524HisHis: 0.524 ± 0.022	0.446HisIle: 0.446 ± 0.02	0.261HisLys: 0.261 ± 0.016	2.287HisLeu: 2.287 ± 0.045	0.26HisMet: 0.26 ± 0.016	0.312HisAsn: 0.312 ± 0.016	1.493HisPro: 1.493 ± 0.036	0.478HisGln: 0.478 ± 0.019	1.712HisArg: 1.712 ± 0.035	0.975HisSer: 0.975 ± 0.026	0.923HisThr: 0.923 ± 0.031	2.026HisVal: 2.026 ± 0.04	0.302HisTrp: 0.302 ± 0.016	0.425HisTyr: 0.425 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	3.659IleAla: 3.659 ± 0.06	0.199IleCys: 0.199 ± 0.012	1.904IleAsp: 1.904 ± 0.037	1.477IleGlu: 1.477 ± 0.038	0.553IlePhe: 0.553 ± 0.023	2.756IleGly: 2.756 ± 0.056	0.411IleHis: 0.411 ± 0.02	0.624IleIle: 0.624 ± 0.028	0.499IleLys: 0.499 ± 0.022	1.791IleLeu: 1.791 ± 0.048	0.268IleMet: 0.268 ± 0.014	0.55IleAsn: 0.55 ± 0.024	1.267IlePro: 1.267 ± 0.036	0.502IleGln: 0.502 ± 0.022	1.474IleArg: 1.474 ± 0.041	1.47IleSer: 1.47 ± 0.037	1.708IleThr: 1.708 ± 0.039	2.34IleVal: 2.34 ± 0.055	0.265IleTrp: 0.265 ± 0.014	0.465IleTyr: 0.465 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	2.354LysAla: 2.354 ± 0.058	0.067LysCys: 0.067 ± 0.006	0.961LysAsp: 0.961 ± 0.03	0.699LysGlu: 0.699 ± 0.028	0.346LysPhe: 0.346 ± 0.017	1.583LysGly: 1.583 ± 0.043	0.373LysHis: 0.373 ± 0.02	0.563LysIle: 0.563 ± 0.022	0.535LysLys: 0.535 ± 0.029	1.471LysLeu: 1.471 ± 0.038	0.236LysMet: 0.236 ± 0.014	0.356LysAsn: 0.356 ± 0.018	1.039LysPro: 1.039 ± 0.028	0.567LysGln: 0.567 ± 0.027	1.103LysArg: 1.103 ± 0.033	0.928LysSer: 0.928 ± 0.035	1.028LysThr: 1.028 ± 0.032	1.655LysVal: 1.655 ± 0.049	0.181LysTrp: 0.181 ± 0.013	0.343LysTyr: 0.343 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	16.857LeuAla: 16.857 ± 0.16	0.735LeuCys: 0.735 ± 0.021	7.082LeuAsp: 7.082 ± 0.084	5.736LeuGlu: 5.736 ± 0.095	2.271LeuPhe: 2.271 ± 0.05	9.958LeuGly: 9.958 ± 0.112	2.301LeuHis: 2.301 ± 0.05	1.783LeuIle: 1.783 ± 0.048	1.404LeuLys: 1.404 ± 0.039	12.441LeuLeu: 12.441 ± 0.165	1.238LeuMet: 1.238 ± 0.03	1.321LeuAsn: 1.321 ± 0.036	6.603LeuPro: 6.603 ± 0.08	2.734LeuGln: 2.734 ± 0.051	9.31LeuArg: 9.31 ± 0.114	5.749LeuSer: 5.749 ± 0.07	5.982LeuThr: 5.982 ± 0.07	11.693LeuVal: 11.693 ± 0.122	1.243LeuTrp: 1.243 ± 0.033	1.456LeuTyr: 1.456 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	1.948MetAla: 1.948 ± 0.041	0.096MetCys: 0.096 ± 0.009	0.707MetAsp: 0.707 ± 0.023	0.536MetGlu: 0.536 ± 0.019	0.338MetPhe: 0.338 ± 0.018	1.114MetGly: 1.114 ± 0.03	0.321MetHis: 0.321 ± 0.015	0.368MetIle: 0.368 ± 0.017	0.268MetLys: 0.268 ± 0.014	1.465MetLeu: 1.465 ± 0.039	0.206MetMet: 0.206 ± 0.014	0.248MetAsn: 0.248 ± 0.013	0.99MetPro: 0.99 ± 0.027	0.456MetGln: 0.456 ± 0.017	1.208MetArg: 1.208 ± 0.032	1.326MetSer: 1.326 ± 0.035	1.413MetThr: 1.413 ± 0.033	1.189MetVal: 1.189 ± 0.029	0.16MetTrp: 0.16 ± 0.011	0.238MetTyr: 0.238 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	1.953AsnAla: 1.953 ± 0.047	0.121AsnCys: 0.121 ± 0.011	0.928AsnAsp: 0.928 ± 0.032	0.641AsnGlu: 0.641 ± 0.024	0.361AsnPhe: 0.361 ± 0.017	1.601AsnGly: 1.601 ± 0.05	0.266AsnHis: 0.266 ± 0.014	0.468AsnIle: 0.468 ± 0.021	0.275AsnLys: 0.275 ± 0.015	1.45AsnLeu: 1.45 ± 0.036	0.189AsnMet: 0.189 ± 0.013	0.341AsnAsn: 0.341 ± 0.018	1.163AsnPro: 1.163 ± 0.03	0.388AsnGln: 0.388 ± 0.019	1.023AsnArg: 1.023 ± 0.029	0.772AsnSer: 0.772 ± 0.028	0.837AsnThr: 0.837 ± 0.029	1.366AsnVal: 1.366 ± 0.038	0.226AsnTrp: 0.226 ± 0.014	0.353AsnTyr: 0.353 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	9.166ProAla: 9.166 ± 0.124	0.282ProCys: 0.282 ± 0.015	4.048ProAsp: 4.048 ± 0.06	3.713ProGlu: 3.713 ± 0.066	1.417ProPhe: 1.417 ± 0.032	6.348ProGly: 6.348 ± 0.087	1.195ProHis: 1.195 ± 0.032	1.02ProIle: 1.02 ± 0.034	0.871ProLys: 0.871 ± 0.028	5.567ProLeu: 5.567 ± 0.071	0.821ProMet: 0.821 ± 0.022	0.774ProAsn: 0.774 ± 0.028	3.125ProPro: 3.125 ± 0.065	1.607ProGln: 1.607 ± 0.034	4.004ProArg: 4.004 ± 0.068	3.521ProSer: 3.521 ± 0.062	3.415ProThr: 3.415 ± 0.072	5.933ProVal: 5.933 ± 0.08	0.896ProTrp: 0.896 ± 0.031	1.035ProTyr: 1.035 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.798GlnAla: 3.798 ± 0.062	0.135GlnCys: 0.135 ± 0.009	1.24GlnAsp: 1.24 ± 0.031	1.275GlnGlu: 1.275 ± 0.033	0.654GlnPhe: 0.654 ± 0.021	2.208GlnGly: 2.208 ± 0.043	0.617GlnHis: 0.617 ± 0.021	0.696GlnIle: 0.696 ± 0.027	0.459GlnLys: 0.459 ± 0.021	3.167GlnLeu: 3.167 ± 0.049	0.407GlnMet: 0.407 ± 0.021	0.389GlnAsn: 0.389 ± 0.019	1.657GlnPro: 1.657 ± 0.04	1.263GlnGln: 1.263 ± 0.033	2.495GlnArg: 2.495 ± 0.041	1.266GlnSer: 1.266 ± 0.036	1.441GlnThr: 1.441 ± 0.031	3.079GlnVal: 3.079 ± 0.043	0.47GlnTrp: 0.47 ± 0.018	0.473GlnTyr: 0.473 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	10.546ArgAla: 10.546 ± 0.111	0.508ArgCys: 0.508 ± 0.02	4.275ArgAsp: 4.275 ± 0.059	4.404ArgGlu: 4.404 ± 0.066	2.125ArgPhe: 2.125 ± 0.041	6.122ArgGly: 6.122 ± 0.074	1.749ArgHis: 1.749 ± 0.035	2.372ArgIle: 2.372 ± 0.049	1.095ArgLys: 1.095 ± 0.033	9.0ArgLeu: 9.0 ± 0.107	1.539ArgMet: 1.539 ± 0.031	1.069ArgAsn: 1.069 ± 0.033	4.587ArgPro: 4.587 ± 0.071	2.133ArgGln: 2.133 ± 0.041	7.98ArgArg: 7.98 ± 0.116	4.752ArgSer: 4.752 ± 0.056	5.157ArgThr: 5.157 ± 0.063	7.075ArgVal: 7.075 ± 0.079	1.504ArgTrp: 1.504 ± 0.032	1.524ArgTyr: 1.524 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	8.146SerAla: 8.146 ± 0.102	0.376SerCys: 0.376 ± 0.019	3.065SerAsp: 3.065 ± 0.052	2.475SerGlu: 2.475 ± 0.044	1.715SerPhe: 1.715 ± 0.037	6.331SerGly: 6.331 ± 0.079	1.0SerHis: 1.0 ± 0.027	1.537SerIle: 1.537 ± 0.036	0.964SerLys: 0.964 ± 0.031	5.678SerLeu: 5.678 ± 0.068	1.074SerMet: 1.074 ± 0.029	0.876SerAsn: 0.876 ± 0.031	3.479SerPro: 3.479 ± 0.054	1.3SerGln: 1.3 ± 0.034	4.155SerArg: 4.155 ± 0.055	4.122SerSer: 4.122 ± 0.072	3.877SerThr: 3.877 ± 0.064	5.261SerVal: 5.261 ± 0.078	1.103SerTrp: 1.103 ± 0.044	1.155SerTyr: 1.155 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	8.43ThrAla: 8.43 ± 0.095	0.425ThrCys: 0.425 ± 0.019	3.168ThrAsp: 3.168 ± 0.059	2.429ThrGlu: 2.429 ± 0.048	1.597ThrPhe: 1.597 ± 0.036	6.455ThrGly: 6.455 ± 0.087	1.085ThrHis: 1.085 ± 0.028	1.542ThrIle: 1.542 ± 0.041	1.06ThrLys: 1.06 ± 0.034	6.035ThrLeu: 6.035 ± 0.074	0.823ThrMet: 0.823 ± 0.026	0.963ThrAsn: 0.963 ± 0.03	3.992ThrPro: 3.992 ± 0.074	1.27ThrGln: 1.27 ± 0.029	4.019ThrArg: 4.019 ± 0.051	3.897ThrSer: 3.897 ± 0.064	4.374ThrThr: 4.374 ± 0.092	6.196ThrVal: 6.196 ± 0.087	1.002ThrTrp: 1.002 ± 0.032	1.37ThrTyr: 1.37 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	13.992ValAla: 13.992 ± 0.137	0.707ValCys: 0.707 ± 0.024	6.206ValAsp: 6.206 ± 0.073	5.832ValGlu: 5.832 ± 0.082	2.389ValPhe: 2.389 ± 0.046	8.082ValGly: 8.082 ± 0.096	2.034ValHis: 2.034 ± 0.04	2.277ValIle: 2.277 ± 0.046	1.51ValLys: 1.51 ± 0.038	11.638ValLeu: 11.638 ± 0.123	1.29ValMet: 1.29 ± 0.031	1.587ValAsn: 1.587 ± 0.039	5.914ValPro: 5.914 ± 0.08	2.487ValGln: 2.487 ± 0.044	7.902ValArg: 7.902 ± 0.079	5.515ValSer: 5.515 ± 0.076	6.139ValThr: 6.139 ± 0.075	12.047ValVal: 12.047 ± 0.145	1.238ValTrp: 1.238 ± 0.033	1.59ValTyr: 1.59 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.831TrpAla: 1.831 ± 0.034	0.142TrpCys: 0.142 ± 0.011	0.859TrpAsp: 0.859 ± 0.029	0.628TrpGlu: 0.628 ± 0.022	0.492TrpPhe: 0.492 ± 0.021	1.043TrpGly: 1.043 ± 0.034	0.388TrpHis: 0.388 ± 0.017	0.337TrpIle: 0.337 ± 0.017	0.306TrpLys: 0.306 ± 0.015	1.722TrpLeu: 1.722 ± 0.042	0.254TrpMet: 0.254 ± 0.014	0.329TrpAsn: 0.329 ± 0.016	0.789TrpPro: 0.789 ± 0.024	0.58TrpGln: 0.58 ± 0.021	1.337TrpArg: 1.337 ± 0.038	1.136TrpSer: 1.136 ± 0.031	1.001TrpThr: 1.001 ± 0.034	1.327TrpVal: 1.327 ± 0.03	0.333TrpTrp: 0.333 ± 0.016	0.304TrpTyr: 0.304 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.927TyrAla: 2.927 ± 0.046	0.143TyrCys: 0.143 ± 0.011	1.492TyrAsp: 1.492 ± 0.039	0.937TyrGlu: 0.937 ± 0.031	0.519TyrPhe: 0.519 ± 0.021	1.821TyrGly: 1.821 ± 0.041	0.305TyrHis: 0.305 ± 0.015	0.364TyrIle: 0.364 ± 0.017	0.315TyrLys: 0.315 ± 0.017	1.899TyrLeu: 1.899 ± 0.04	0.164TyrMet: 0.164 ± 0.011	0.351TyrAsn: 0.351 ± 0.017	0.87TyrPro: 0.87 ± 0.026	0.506TyrGln: 0.506 ± 0.019	1.492TyrArg: 1.492 ± 0.035	1.103TyrSer: 1.103 ± 0.036	0.986TyrThr: 0.986 ± 0.038	1.816TyrVal: 1.816 ± 0.037	0.293TyrTrp: 0.293 ± 0.015	0.436TyrTyr: 0.436 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3836 proteins (1277826 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---