Amino acid dipepetide frequency for Marinilabilia rubra

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.414AlaAla: 4.414 ± 0.074	0.609AlaCys: 0.609 ± 0.024	3.622AlaAsp: 3.622 ± 0.059	4.032AlaGlu: 4.032 ± 0.054	3.433AlaPhe: 3.433 ± 0.051	5.285AlaGly: 5.285 ± 0.084	1.173AlaHis: 1.173 ± 0.027	4.402AlaIle: 4.402 ± 0.061	3.403AlaLys: 3.403 ± 0.057	6.118AlaLeu: 6.118 ± 0.085	1.596AlaMet: 1.596 ± 0.037	2.976AlaAsn: 2.976 ± 0.055	2.207AlaPro: 2.207 ± 0.037	2.114AlaGln: 2.114 ± 0.043	3.05AlaArg: 3.05 ± 0.05	4.316AlaSer: 4.316 ± 0.067	3.173AlaThr: 3.173 ± 0.059	4.105AlaVal: 4.105 ± 0.065	0.819AlaTrp: 0.819 ± 0.022	2.243AlaTyr: 2.243 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.408CysAla: 0.408 ± 0.018	0.095CysCys: 0.095 ± 0.009	0.437CysAsp: 0.437 ± 0.018	0.464CysGlu: 0.464 ± 0.02	0.417CysPhe: 0.417 ± 0.019	0.603CysGly: 0.603 ± 0.024	0.219CysHis: 0.219 ± 0.014	0.479CysIle: 0.479 ± 0.021	0.463CysLys: 0.463 ± 0.018	0.677CysLeu: 0.677 ± 0.02	0.153CysMet: 0.153 ± 0.009	0.436CysAsn: 0.436 ± 0.018	0.369CysPro: 0.369 ± 0.019	0.281CysGln: 0.281 ± 0.014	0.384CysArg: 0.384 ± 0.018	0.553CysSer: 0.553 ± 0.028	0.382CysThr: 0.382 ± 0.02	0.416CysVal: 0.416 ± 0.017	0.087CysTrp: 0.087 ± 0.009	0.281CysTyr: 0.281 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.566AspAla: 3.566 ± 0.055	0.371AspCys: 0.371 ± 0.015	3.078AspAsp: 3.078 ± 0.065	4.312AspGlu: 4.312 ± 0.062	3.563AspPhe: 3.563 ± 0.054	4.15AspGly: 4.15 ± 0.091	1.175AspHis: 1.175 ± 0.03	4.111AspIle: 4.111 ± 0.055	3.635AspLys: 3.635 ± 0.054	5.531AspLeu: 5.531 ± 0.062	1.353AspMet: 1.353 ± 0.033	2.962AspAsn: 2.962 ± 0.048	2.333AspPro: 2.333 ± 0.047	2.064AspGln: 2.064 ± 0.037	2.332AspArg: 2.332 ± 0.037	3.299AspSer: 3.299 ± 0.06	2.305AspThr: 2.305 ± 0.048	3.784AspVal: 3.784 ± 0.061	0.871AspTrp: 0.871 ± 0.027	2.753AspTyr: 2.753 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	4.723GluAla: 4.723 ± 0.065	0.396GluCys: 0.396 ± 0.019	3.841GluAsp: 3.841 ± 0.048	5.56GluGlu: 5.56 ± 0.08	2.909GluPhe: 2.909 ± 0.045	4.586GluGly: 4.586 ± 0.063	1.155GluHis: 1.155 ± 0.03	5.372GluIle: 5.372 ± 0.064	6.232GluLys: 6.232 ± 0.081	6.421GluLeu: 6.421 ± 0.07	2.086GluMet: 2.086 ± 0.04	4.336GluAsn: 4.336 ± 0.055	1.989GluPro: 1.989 ± 0.041	2.401GluGln: 2.401 ± 0.041	2.873GluArg: 2.873 ± 0.048	3.806GluSer: 3.806 ± 0.051	3.593GluThr: 3.593 ± 0.056	4.835GluVal: 4.835 ± 0.068	0.897GluTrp: 0.897 ± 0.029	2.606GluTyr: 2.606 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	2.886PheAla: 2.886 ± 0.046	0.469PheCys: 0.469 ± 0.021	3.242PheAsp: 3.242 ± 0.041	3.433PheGlu: 3.433 ± 0.055	3.104PhePhe: 3.104 ± 0.057	3.372PheGly: 3.372 ± 0.055	0.905PheHis: 0.905 ± 0.024	3.397PheIle: 3.397 ± 0.053	3.058PheLys: 3.058 ± 0.051	4.932PheLeu: 4.932 ± 0.072	1.251PheMet: 1.251 ± 0.029	2.941PheAsn: 2.941 ± 0.052	1.899PhePro: 1.899 ± 0.036	1.531PheGln: 1.531 ± 0.032	2.238PheArg: 2.238 ± 0.04	4.404PheSer: 4.404 ± 0.066	2.692PheThr: 2.692 ± 0.045	3.072PheVal: 3.072 ± 0.052	0.682PheTrp: 0.682 ± 0.022	2.084PheTyr: 2.084 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.379GlyAla: 4.379 ± 0.066	0.723GlyCys: 0.723 ± 0.037	3.88GlyAsp: 3.88 ± 0.065	4.706GlyGlu: 4.706 ± 0.065	3.809GlyPhe: 3.809 ± 0.054	5.087GlyGly: 5.087 ± 0.077	1.383GlyHis: 1.383 ± 0.032	5.471GlyIle: 5.471 ± 0.079	4.841GlyLys: 4.841 ± 0.068	6.397GlyLeu: 6.397 ± 0.084	1.93GlyMet: 1.93 ± 0.044	3.748GlyAsn: 3.748 ± 0.068	1.819GlyPro: 1.819 ± 0.038	2.307GlyGln: 2.307 ± 0.041	2.937GlyArg: 2.937 ± 0.049	4.347GlySer: 4.347 ± 0.091	3.983GlyThr: 3.983 ± 0.093	4.635GlyVal: 4.635 ± 0.067	0.98GlyTrp: 0.98 ± 0.028	3.053GlyTyr: 3.053 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.078HisAla: 1.078 ± 0.028	0.203HisCys: 0.203 ± 0.011	0.972HisAsp: 0.972 ± 0.028	1.173HisGlu: 1.173 ± 0.032	1.25HisPhe: 1.25 ± 0.031	1.241HisGly: 1.241 ± 0.032	0.56HisHis: 0.56 ± 0.022	1.301HisIle: 1.301 ± 0.028	1.218HisLys: 1.218 ± 0.031	2.008HisLeu: 2.008 ± 0.044	0.37HisMet: 0.37 ± 0.017	0.967HisAsn: 0.967 ± 0.024	1.12HisPro: 1.12 ± 0.029	0.788HisGln: 0.788 ± 0.024	0.854HisArg: 0.854 ± 0.024	1.259HisSer: 1.259 ± 0.032	0.911HisThr: 0.911 ± 0.026	1.016HisVal: 1.016 ± 0.027	0.273HisTrp: 0.273 ± 0.012	0.896HisTyr: 0.896 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.473IleAla: 4.473 ± 0.069	0.526IleCys: 0.526 ± 0.021	4.519IleAsp: 4.519 ± 0.054	5.206IleGlu: 5.206 ± 0.061	3.191IlePhe: 3.191 ± 0.055	4.48IleGly: 4.48 ± 0.065	1.317IleHis: 1.317 ± 0.032	4.806IleIle: 4.806 ± 0.072	4.559IleLys: 4.559 ± 0.072	6.121IleLeu: 6.121 ± 0.076	1.36IleMet: 1.36 ± 0.031	3.976IleAsn: 3.976 ± 0.051	3.173IlePro: 3.173 ± 0.05	2.187IleGln: 2.187 ± 0.037	3.163IleArg: 3.163 ± 0.05	5.373IleSer: 5.373 ± 0.082	3.933IleThr: 3.933 ± 0.084	4.165IleVal: 4.165 ± 0.06	0.791IleTrp: 0.791 ± 0.031	2.44IleTyr: 2.44 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.54LysAla: 4.54 ± 0.066	0.384LysCys: 0.384 ± 0.017	3.763LysAsp: 3.763 ± 0.06	5.684LysGlu: 5.684 ± 0.078	2.391LysPhe: 2.391 ± 0.045	4.472LysGly: 4.472 ± 0.053	1.344LysHis: 1.344 ± 0.034	4.691LysIle: 4.691 ± 0.06	5.481LysLys: 5.481 ± 0.097	5.55LysLeu: 5.55 ± 0.072	1.908LysMet: 1.908 ± 0.036	3.892LysAsn: 3.892 ± 0.06	2.511LysPro: 2.511 ± 0.05	2.326LysGln: 2.326 ± 0.047	2.906LysArg: 2.906 ± 0.047	4.008LysSer: 4.008 ± 0.064	3.759LysThr: 3.759 ± 0.057	4.335LysVal: 4.335 ± 0.054	0.882LysTrp: 0.882 ± 0.027	2.638LysTyr: 2.638 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	5.919LeuAla: 5.919 ± 0.079	0.627LeuCys: 0.627 ± 0.019	4.874LeuAsp: 4.874 ± 0.06	6.044LeuGlu: 6.044 ± 0.064	4.94LeuPhe: 4.94 ± 0.082	5.677LeuGly: 5.677 ± 0.077	1.621LeuHis: 1.621 ± 0.036	6.371LeuIle: 6.371 ± 0.076	7.432LeuLys: 7.432 ± 0.088	8.812LeuLeu: 8.812 ± 0.101	2.391LeuMet: 2.391 ± 0.052	5.284LeuAsn: 5.284 ± 0.067	3.964LeuPro: 3.964 ± 0.059	3.003LeuGln: 3.003 ± 0.05	3.866LeuArg: 3.866 ± 0.063	7.037LeuSer: 7.037 ± 0.083	4.931LeuThr: 4.931 ± 0.063	5.529LeuVal: 5.529 ± 0.08	1.041LeuTrp: 1.041 ± 0.031	3.033LeuTyr: 3.033 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.012MetAla: 2.012 ± 0.037	0.12MetCys: 0.12 ± 0.009	1.49MetAsp: 1.49 ± 0.031	1.733MetGlu: 1.733 ± 0.037	0.946MetPhe: 0.946 ± 0.029	1.943MetGly: 1.943 ± 0.045	0.453MetHis: 0.453 ± 0.019	1.507MetIle: 1.507 ± 0.034	1.982MetLys: 1.982 ± 0.038	2.128MetLeu: 2.128 ± 0.042	0.649MetMet: 0.649 ± 0.025	1.282MetAsn: 1.282 ± 0.027	1.076MetPro: 1.076 ± 0.029	0.948MetGln: 0.948 ± 0.028	1.059MetArg: 1.059 ± 0.029	1.485MetSer: 1.485 ± 0.029	1.205MetThr: 1.205 ± 0.028	1.812MetVal: 1.812 ± 0.041	0.231MetTrp: 0.231 ± 0.012	0.616MetTyr: 0.616 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.242AsnAla: 3.242 ± 0.048	0.41AsnCys: 0.41 ± 0.023	2.859AsnAsp: 2.859 ± 0.048	3.522AsnGlu: 3.522 ± 0.052	2.472AsnPhe: 2.472 ± 0.042	3.99AsnGly: 3.99 ± 0.07	1.191AsnHis: 1.191 ± 0.032	4.058AsnIle: 4.058 ± 0.052	3.275AsnLys: 3.275 ± 0.056	5.051AsnLeu: 5.051 ± 0.06	1.277AsnMet: 1.277 ± 0.029	3.13AsnAsn: 3.13 ± 0.064	2.831AsnPro: 2.831 ± 0.046	2.213AsnGln: 2.213 ± 0.038	2.391AsnArg: 2.391 ± 0.041	3.48AsnSer: 3.48 ± 0.065	2.839AsnThr: 2.839 ± 0.054	3.23AsnVal: 3.23 ± 0.051	0.758AsnTrp: 0.758 ± 0.025	2.349AsnTyr: 2.349 ± 0.052	0.0AsnXaa: 0.0 ± 0.0
Pro	2.534ProAla: 2.534 ± 0.041	0.234ProCys: 0.234 ± 0.012	3.007ProAsp: 3.007 ± 0.046	3.841ProGlu: 3.841 ± 0.057	2.114ProPhe: 2.114 ± 0.039	3.219ProGly: 3.219 ± 0.049	0.819ProHis: 0.819 ± 0.026	2.024ProIle: 2.024 ± 0.04	1.891ProLys: 1.891 ± 0.043	3.444ProLeu: 3.444 ± 0.053	0.872ProMet: 0.872 ± 0.024	1.859ProAsn: 1.859 ± 0.041	1.135ProPro: 1.135 ± 0.033	1.292ProGln: 1.292 ± 0.032	1.368ProArg: 1.368 ± 0.031	2.513ProSer: 2.513 ± 0.047	1.665ProThr: 1.665 ± 0.045	3.408ProVal: 3.408 ± 0.058	0.494ProTrp: 0.494 ± 0.017	1.461ProTyr: 1.461 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.114GlnAla: 2.114 ± 0.042	0.199GlnCys: 0.199 ± 0.011	1.606GlnAsp: 1.606 ± 0.032	2.375GlnGlu: 2.375 ± 0.046	1.478GlnPhe: 1.478 ± 0.029	2.004GlnGly: 2.004 ± 0.04	0.618GlnHis: 0.618 ± 0.02	2.358GlnIle: 2.358 ± 0.044	2.937GlnLys: 2.937 ± 0.052	3.2GlnLeu: 3.2 ± 0.053	1.004GlnMet: 1.004 ± 0.025	2.092GlnAsn: 2.092 ± 0.044	1.295GlnPro: 1.295 ± 0.038	1.376GlnGln: 1.376 ± 0.037	1.478GlnArg: 1.478 ± 0.03	2.141GlnSer: 2.141 ± 0.035	1.931GlnThr: 1.931 ± 0.044	2.098GlnVal: 2.098 ± 0.043	0.457GlnTrp: 0.457 ± 0.017	1.344GlnTyr: 1.344 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.34ArgAla: 2.34 ± 0.048	0.289ArgCys: 0.289 ± 0.015	2.283ArgAsp: 2.283 ± 0.039	3.195ArgGlu: 3.195 ± 0.051	2.475ArgPhe: 2.475 ± 0.043	2.442ArgGly: 2.442 ± 0.042	0.887ArgHis: 0.887 ± 0.027	3.363ArgIle: 3.363 ± 0.056	3.435ArgLys: 3.435 ± 0.053	4.14ArgLeu: 4.14 ± 0.059	1.146ArgMet: 1.146 ± 0.028	2.51ArgAsn: 2.51 ± 0.044	1.507ArgPro: 1.507 ± 0.033	1.656ArgGln: 1.656 ± 0.035	1.91ArgArg: 1.91 ± 0.038	2.336ArgSer: 2.336 ± 0.046	2.017ArgThr: 2.017 ± 0.031	2.62ArgVal: 2.62 ± 0.043	0.58ArgTrp: 0.58 ± 0.024	1.912ArgTyr: 1.912 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	4.072SerAla: 4.072 ± 0.059	0.584SerCys: 0.584 ± 0.02	4.026SerAsp: 4.026 ± 0.058	4.623SerGlu: 4.623 ± 0.069	3.874SerPhe: 3.874 ± 0.057	5.714SerGly: 5.714 ± 0.099	1.335SerHis: 1.335 ± 0.03	4.391SerIle: 4.391 ± 0.071	3.698SerLys: 3.698 ± 0.057	6.335SerLeu: 6.335 ± 0.075	1.507SerMet: 1.507 ± 0.033	3.222SerAsn: 3.222 ± 0.053	2.643SerPro: 2.643 ± 0.045	2.238SerGln: 2.238 ± 0.044	2.906SerArg: 2.906 ± 0.049	4.57SerSer: 4.57 ± 0.069	3.172SerThr: 3.172 ± 0.054	4.591SerVal: 4.591 ± 0.068	0.865SerTrp: 0.865 ± 0.024	2.475SerTyr: 2.475 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	3.316ThrAla: 3.316 ± 0.068	0.35ThrCys: 0.35 ± 0.021	3.125ThrAsp: 3.125 ± 0.059	3.095ThrGlu: 3.095 ± 0.05	2.614ThrPhe: 2.614 ± 0.042	4.585ThrGly: 4.585 ± 0.072	0.997ThrHis: 0.997 ± 0.022	4.026ThrIle: 4.026 ± 0.082	2.608ThrLys: 2.608 ± 0.047	4.744ThrLeu: 4.744 ± 0.067	1.026ThrMet: 1.026 ± 0.026	2.549ThrAsn: 2.549 ± 0.045	2.55ThrPro: 2.55 ± 0.04	1.542ThrGln: 1.542 ± 0.034	2.157ThrArg: 2.157 ± 0.042	3.511ThrSer: 3.511 ± 0.07	2.783ThrThr: 2.783 ± 0.05	3.347ThrVal: 3.347 ± 0.083	0.654ThrTrp: 0.654 ± 0.023	1.884ThrTyr: 1.884 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	4.128ValAla: 4.128 ± 0.068	0.546ValCys: 0.546 ± 0.02	3.899ValAsp: 3.899 ± 0.07	4.324ValGlu: 4.324 ± 0.05	3.731ValPhe: 3.731 ± 0.062	3.834ValGly: 3.834 ± 0.058	1.106ValHis: 1.106 ± 0.029	4.527ValIle: 4.527 ± 0.06	4.267ValLys: 4.267 ± 0.06	5.938ValLeu: 5.938 ± 0.076	1.56ValMet: 1.56 ± 0.035	3.469ValAsn: 3.469 ± 0.051	2.724ValPro: 2.724 ± 0.044	1.714ValGln: 1.714 ± 0.029	2.667ValArg: 2.667 ± 0.047	4.796ValSer: 4.796 ± 0.065	3.532ValThr: 3.532 ± 0.095	4.765ValVal: 4.765 ± 0.069	0.74ValTrp: 0.74 ± 0.024	2.354ValTyr: 2.354 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.733TrpAla: 0.733 ± 0.024	0.119TrpCys: 0.119 ± 0.01	0.791TrpAsp: 0.791 ± 0.025	0.873TrpGlu: 0.873 ± 0.026	0.67TrpPhe: 0.67 ± 0.021	0.957TrpGly: 0.957 ± 0.024	0.332TrpHis: 0.332 ± 0.015	0.832TrpIle: 0.832 ± 0.028	0.769TrpLys: 0.769 ± 0.026	1.174TrpLeu: 1.174 ± 0.03	0.4TrpMet: 0.4 ± 0.017	0.706TrpAsn: 0.706 ± 0.02	0.406TrpPro: 0.406 ± 0.016	0.551TrpGln: 0.551 ± 0.021	0.572TrpArg: 0.572 ± 0.021	0.824TrpSer: 0.824 ± 0.027	0.657TrpThr: 0.657 ± 0.026	0.795TrpVal: 0.795 ± 0.026	0.218TrpTrp: 0.218 ± 0.012	0.481TrpTyr: 0.481 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.214TyrAla: 2.214 ± 0.039	0.349TyrCys: 0.349 ± 0.016	2.235TyrAsp: 2.235 ± 0.043	2.424TyrGlu: 2.424 ± 0.043	2.212TyrPhe: 2.212 ± 0.045	2.775TyrGly: 2.775 ± 0.047	0.868TyrHis: 0.868 ± 0.023	2.272TyrIle: 2.272 ± 0.044	2.278TyrLys: 2.278 ± 0.047	3.676TyrLeu: 3.676 ± 0.058	0.838TyrMet: 0.838 ± 0.027	2.23TyrAsn: 2.23 ± 0.048	1.644TyrPro: 1.644 ± 0.034	1.571TyrGln: 1.571 ± 0.038	1.931TyrArg: 1.931 ± 0.041	2.783TyrSer: 2.783 ± 0.047	1.998TyrThr: 1.998 ± 0.055	2.065TyrVal: 2.065 ± 0.037	0.54TyrTrp: 0.54 ± 0.02	1.777TyrTyr: 1.777 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4010 proteins (1511230 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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