Amino acid dipepetide frequency for Kocuria coralli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.672AlaAla: 17.672 ± 0.174	0.805AlaCys: 0.805 ± 0.028	7.095AlaAsp: 7.095 ± 0.097	8.613AlaGlu: 8.613 ± 0.116	3.514AlaPhe: 3.514 ± 0.069	12.482AlaGly: 12.482 ± 0.136	2.352AlaHis: 2.352 ± 0.054	4.908AlaIle: 4.908 ± 0.073	2.478AlaLys: 2.478 ± 0.073	12.695AlaLeu: 12.695 ± 0.142	2.841AlaMet: 2.841 ± 0.052	2.038AlaAsn: 2.038 ± 0.043	6.154AlaPro: 6.154 ± 0.098	4.222AlaGln: 4.222 ± 0.072	8.685AlaArg: 8.685 ± 0.102	6.468AlaSer: 6.468 ± 0.081	6.355AlaThr: 6.355 ± 0.077	11.148AlaVal: 11.148 ± 0.137	1.829AlaTrp: 1.829 ± 0.047	2.167AlaTyr: 2.167 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.729CysAla: 0.729 ± 0.026	0.066CysCys: 0.066 ± 0.009	0.351CysAsp: 0.351 ± 0.018	0.359CysGlu: 0.359 ± 0.023	0.21CysPhe: 0.21 ± 0.013	0.726CysGly: 0.726 ± 0.028	0.159CysHis: 0.159 ± 0.014	0.237CysIle: 0.237 ± 0.017	0.088CysLys: 0.088 ± 0.009	0.612CysLeu: 0.612 ± 0.024	0.127CysMet: 0.127 ± 0.011	0.124CysAsn: 0.124 ± 0.012	0.342CysPro: 0.342 ± 0.02	0.164CysGln: 0.164 ± 0.014	0.465CysArg: 0.465 ± 0.025	0.41CysSer: 0.41 ± 0.019	0.371CysThr: 0.371 ± 0.02	0.504CysVal: 0.504 ± 0.026	0.089CysTrp: 0.089 ± 0.01	0.133CysTyr: 0.133 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.106AspAla: 7.106 ± 0.102	0.284AspCys: 0.284 ± 0.018	4.228AspAsp: 4.228 ± 0.067	4.105AspGlu: 4.105 ± 0.072	1.67AspPhe: 1.67 ± 0.042	6.119AspGly: 6.119 ± 0.098	1.413AspHis: 1.413 ± 0.037	2.044AspIle: 2.044 ± 0.049	0.981AspLys: 0.981 ± 0.034	6.637AspLeu: 6.637 ± 0.089	0.924AspMet: 0.924 ± 0.032	0.878AspAsn: 0.878 ± 0.034	4.645AspPro: 4.645 ± 0.078	1.944AspGln: 1.944 ± 0.046	4.735AspArg: 4.735 ± 0.071	3.023AspSer: 3.023 ± 0.054	2.777AspThr: 2.777 ± 0.056	4.828AspVal: 4.828 ± 0.072	0.896AspTrp: 0.896 ± 0.034	1.327AspTyr: 1.327 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	8.029GluAla: 8.029 ± 0.106	0.323GluCys: 0.323 ± 0.018	3.813GluAsp: 3.813 ± 0.057	3.979GluGlu: 3.979 ± 0.081	1.742GluPhe: 1.742 ± 0.043	4.597GluGly: 4.597 ± 0.08	1.83GluHis: 1.83 ± 0.048	3.068GluIle: 3.068 ± 0.065	1.521GluLys: 1.521 ± 0.041	6.532GluLeu: 6.532 ± 0.084	1.123GluMet: 1.123 ± 0.038	1.531GluAsn: 1.531 ± 0.04	3.286GluPro: 3.286 ± 0.064	2.698GluGln: 2.698 ± 0.053	4.937GluArg: 4.937 ± 0.075	3.225GluSer: 3.225 ± 0.066	3.516GluThr: 3.516 ± 0.057	5.009GluVal: 5.009 ± 0.084	0.786GluTrp: 0.786 ± 0.027	1.132GluTyr: 1.132 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.592PheAla: 3.592 ± 0.06	0.214PheCys: 0.214 ± 0.015	2.116PheAsp: 2.116 ± 0.045	1.681PheGlu: 1.681 ± 0.05	1.07PhePhe: 1.07 ± 0.039	3.161PheGly: 3.161 ± 0.061	0.611PheHis: 0.611 ± 0.026	1.159PheIle: 1.159 ± 0.04	0.538PheLys: 0.538 ± 0.025	2.844PheLeu: 2.844 ± 0.056	0.601PheMet: 0.601 ± 0.024	0.711PheAsn: 0.711 ± 0.028	1.396PhePro: 1.396 ± 0.038	0.777PheGln: 0.777 ± 0.026	1.724PheArg: 1.724 ± 0.042	1.776PheSer: 1.776 ± 0.039	2.027PheThr: 2.027 ± 0.048	2.512PheVal: 2.512 ± 0.056	0.458PheTrp: 0.458 ± 0.025	0.68PheTyr: 0.68 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.341GlyAla: 10.341 ± 0.111	0.684GlyCys: 0.684 ± 0.028	4.973GlyAsp: 4.973 ± 0.075	5.425GlyGlu: 5.425 ± 0.069	3.094GlyPhe: 3.094 ± 0.057	7.903GlyGly: 7.903 ± 0.099	2.146GlyHis: 2.146 ± 0.05	4.327GlyIle: 4.327 ± 0.071	2.34GlyLys: 2.34 ± 0.054	9.275GlyLeu: 9.275 ± 0.125	2.143GlyMet: 2.143 ± 0.052	1.87GlyAsn: 1.87 ± 0.049	4.45GlyPro: 4.45 ± 0.074	3.256GlyGln: 3.256 ± 0.065	6.771GlyArg: 6.771 ± 0.093	5.87GlySer: 5.87 ± 0.083	5.733GlyThr: 5.733 ± 0.091	7.419GlyVal: 7.419 ± 0.088	1.649GlyTrp: 1.649 ± 0.041	2.173GlyTyr: 2.173 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.299HisAla: 2.299 ± 0.052	0.165HisCys: 0.165 ± 0.013	1.499HisAsp: 1.499 ± 0.042	1.329HisGlu: 1.329 ± 0.037	0.567HisPhe: 0.567 ± 0.027	2.278HisGly: 2.278 ± 0.053	0.663HisHis: 0.663 ± 0.03	0.738HisIle: 0.738 ± 0.027	0.384HisLys: 0.384 ± 0.018	2.323HisLeu: 2.323 ± 0.048	0.368HisMet: 0.368 ± 0.019	0.36HisAsn: 0.36 ± 0.018	1.612HisPro: 1.612 ± 0.04	0.682HisGln: 0.682 ± 0.024	1.981HisArg: 1.981 ± 0.05	1.09HisSer: 1.09 ± 0.031	1.086HisThr: 1.086 ± 0.035	1.708HisVal: 1.708 ± 0.042	0.322HisTrp: 0.322 ± 0.019	0.458HisTyr: 0.458 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.804IleAla: 5.804 ± 0.087	0.308IleCys: 0.308 ± 0.021	2.84IleAsp: 2.84 ± 0.049	2.622IleGlu: 2.622 ± 0.053	1.255IlePhe: 1.255 ± 0.042	4.301IleGly: 4.301 ± 0.074	0.822IleHis: 0.822 ± 0.032	1.491IleIle: 1.491 ± 0.042	0.841IleLys: 0.841 ± 0.031	3.713IleLeu: 3.713 ± 0.066	0.814IleMet: 0.814 ± 0.034	0.959IleAsn: 0.959 ± 0.033	2.271IlePro: 2.271 ± 0.045	1.128IleGln: 1.128 ± 0.037	2.741IleArg: 2.741 ± 0.054	2.502IleSer: 2.502 ± 0.054	2.744IleThr: 2.744 ± 0.056	3.828IleVal: 3.828 ± 0.07	0.462IleTrp: 0.462 ± 0.022	0.728IleTyr: 0.728 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.542LysAla: 2.542 ± 0.068	0.087LysCys: 0.087 ± 0.01	1.293LysAsp: 1.293 ± 0.042	1.125LysGlu: 1.125 ± 0.038	0.485LysPhe: 0.485 ± 0.023	1.603LysGly: 1.603 ± 0.047	0.54LysHis: 0.54 ± 0.024	1.011LysIle: 1.011 ± 0.033	0.825LysLys: 0.825 ± 0.044	1.831LysLeu: 1.831 ± 0.049	0.399LysMet: 0.399 ± 0.02	0.569LysAsn: 0.569 ± 0.025	1.164LysPro: 1.164 ± 0.038	0.692LysGln: 0.692 ± 0.027	1.577LysArg: 1.577 ± 0.042	1.209LysSer: 1.209 ± 0.038	1.326LysThr: 1.326 ± 0.041	1.827LysVal: 1.827 ± 0.044	0.223LysTrp: 0.223 ± 0.019	0.447LysTyr: 0.447 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	12.803LeuAla: 12.803 ± 0.139	0.706LeuCys: 0.706 ± 0.03	6.402LeuAsp: 6.402 ± 0.08	5.878LeuGlu: 5.878 ± 0.094	2.713LeuPhe: 2.713 ± 0.058	9.163LeuGly: 9.163 ± 0.104	2.084LeuHis: 2.084 ± 0.047	4.388LeuIle: 4.388 ± 0.08	2.01LeuLys: 2.01 ± 0.055	10.094LeuLeu: 10.094 ± 0.126	1.933LeuMet: 1.933 ± 0.045	2.091LeuAsn: 2.091 ± 0.05	5.726LeuPro: 5.726 ± 0.075	2.616LeuGln: 2.616 ± 0.046	7.4LeuArg: 7.4 ± 0.092	5.933LeuSer: 5.933 ± 0.078	6.145LeuThr: 6.145 ± 0.075	8.684LeuVal: 8.684 ± 0.095	1.342LeuTrp: 1.342 ± 0.04	1.667LeuTyr: 1.667 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.611MetAla: 2.611 ± 0.052	0.136MetCys: 0.136 ± 0.011	1.049MetAsp: 1.049 ± 0.035	0.946MetGlu: 0.946 ± 0.031	0.585MetPhe: 0.585 ± 0.024	1.669MetGly: 1.669 ± 0.05	0.395MetHis: 0.395 ± 0.018	0.999MetIle: 0.999 ± 0.031	0.476MetLys: 0.476 ± 0.022	2.052MetLeu: 2.052 ± 0.05	0.366MetMet: 0.366 ± 0.021	0.566MetAsn: 0.566 ± 0.027	1.168MetPro: 1.168 ± 0.036	0.585MetGln: 0.585 ± 0.022	1.437MetArg: 1.437 ± 0.04	1.582MetSer: 1.582 ± 0.038	1.743MetThr: 1.743 ± 0.038	1.702MetVal: 1.702 ± 0.044	0.225MetTrp: 0.225 ± 0.016	0.311MetTyr: 0.311 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.42AsnAla: 2.42 ± 0.049	0.13AsnCys: 0.13 ± 0.011	1.192AsnAsp: 1.192 ± 0.039	1.03AsnGlu: 1.03 ± 0.029	0.667AsnPhe: 0.667 ± 0.032	1.835AsnGly: 1.835 ± 0.051	0.444AsnHis: 0.444 ± 0.023	0.892AsnIle: 0.892 ± 0.03	0.42AsnLys: 0.42 ± 0.023	1.965AsnLeu: 1.965 ± 0.05	0.374AsnMet: 0.374 ± 0.018	0.483AsnAsn: 0.483 ± 0.027	1.558AsnPro: 1.558 ± 0.039	0.596AsnGln: 0.596 ± 0.024	1.424AsnArg: 1.424 ± 0.037	1.084AsnSer: 1.084 ± 0.033	1.226AsnThr: 1.226 ± 0.035	1.675AsnVal: 1.675 ± 0.044	0.328AsnTrp: 0.328 ± 0.019	0.482AsnTyr: 0.482 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.308ProAla: 7.308 ± 0.095	0.237ProCys: 0.237 ± 0.015	3.853ProAsp: 3.853 ± 0.062	4.826ProGlu: 4.826 ± 0.07	1.554ProPhe: 1.554 ± 0.045	5.95ProGly: 5.95 ± 0.089	1.185ProHis: 1.185 ± 0.037	1.782ProIle: 1.782 ± 0.045	0.998ProLys: 0.998 ± 0.037	4.672ProLeu: 4.672 ± 0.066	1.06ProMet: 1.06 ± 0.037	0.95ProAsn: 0.95 ± 0.034	2.406ProPro: 2.406 ± 0.058	1.888ProGln: 1.888 ± 0.043	3.544ProArg: 3.544 ± 0.069	3.427ProSer: 3.427 ± 0.055	2.851ProThr: 2.851 ± 0.055	5.236ProVal: 5.236 ± 0.083	0.96ProTrp: 0.96 ± 0.031	1.069ProTyr: 1.069 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.077GlnAla: 4.077 ± 0.061	0.175GlnCys: 0.175 ± 0.013	1.897GlnAsp: 1.897 ± 0.045	2.091GlnGlu: 2.091 ± 0.051	0.839GlnPhe: 0.839 ± 0.031	2.555GlnGly: 2.555 ± 0.056	0.716GlnHis: 0.716 ± 0.029	1.548GlnIle: 1.548 ± 0.036	0.725GlnLys: 0.725 ± 0.033	3.231GlnLeu: 3.231 ± 0.061	0.653GlnMet: 0.653 ± 0.028	0.691GlnAsn: 0.691 ± 0.03	1.778GlnPro: 1.778 ± 0.045	1.414GlnGln: 1.414 ± 0.04	2.855GlnArg: 2.855 ± 0.057	1.548GlnSer: 1.548 ± 0.038	1.501GlnThr: 1.501 ± 0.034	2.592GlnVal: 2.592 ± 0.05	0.558GlnTrp: 0.558 ± 0.023	0.634GlnTyr: 0.634 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	8.243ArgAla: 8.243 ± 0.108	0.456ArgCys: 0.456 ± 0.023	4.041ArgAsp: 4.041 ± 0.076	4.971ArgGlu: 4.971 ± 0.091	2.22ArgPhe: 2.22 ± 0.046	5.4ArgGly: 5.4 ± 0.08	1.66ArgHis: 1.66 ± 0.042	3.605ArgIle: 3.605 ± 0.061	1.648ArgLys: 1.648 ± 0.05	7.2ArgLeu: 7.2 ± 0.096	1.856ArgMet: 1.856 ± 0.04	1.537ArgAsn: 1.537 ± 0.053	4.048ArgPro: 4.048 ± 0.083	2.541ArgGln: 2.541 ± 0.055	6.85ArgArg: 6.85 ± 0.106	4.415ArgSer: 4.415 ± 0.07	4.621ArgThr: 4.621 ± 0.077	5.323ArgVal: 5.323 ± 0.086	1.319ArgTrp: 1.319 ± 0.036	1.581ArgTyr: 1.581 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.101SerAla: 7.101 ± 0.09	0.357SerCys: 0.357 ± 0.019	2.95SerAsp: 2.95 ± 0.055	3.103SerGlu: 3.103 ± 0.06	1.793SerPhe: 1.793 ± 0.042	6.122SerGly: 6.122 ± 0.069	1.164SerHis: 1.164 ± 0.037	2.262SerIle: 2.262 ± 0.049	1.144SerLys: 1.144 ± 0.037	5.272SerLeu: 5.272 ± 0.065	1.457SerMet: 1.457 ± 0.038	1.091SerAsn: 1.091 ± 0.034	3.586SerPro: 3.586 ± 0.056	1.724SerGln: 1.724 ± 0.045	4.126SerArg: 4.126 ± 0.065	3.771SerSer: 3.771 ± 0.064	3.689SerThr: 3.689 ± 0.069	4.706SerVal: 4.706 ± 0.071	1.048SerTrp: 1.048 ± 0.034	1.168SerTyr: 1.168 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	7.652ThrAla: 7.652 ± 0.11	0.319ThrCys: 0.319 ± 0.018	3.494ThrAsp: 3.494 ± 0.057	3.447ThrGlu: 3.447 ± 0.06	1.691ThrPhe: 1.691 ± 0.041	6.209ThrGly: 6.209 ± 0.076	1.162ThrHis: 1.162 ± 0.034	2.336ThrIle: 2.336 ± 0.058	1.059ThrLys: 1.059 ± 0.035	5.232ThrLeu: 5.232 ± 0.076	1.169ThrMet: 1.169 ± 0.034	1.138ThrAsn: 1.138 ± 0.034	3.655ThrPro: 3.655 ± 0.063	1.526ThrGln: 1.526 ± 0.042	3.796ThrArg: 3.796 ± 0.06	3.332ThrSer: 3.332 ± 0.06	3.676ThrThr: 3.676 ± 0.073	5.853ThrVal: 5.853 ± 0.083	0.922ThrTrp: 0.922 ± 0.031	1.146ThrTyr: 1.146 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	10.349ValAla: 10.349 ± 0.117	0.58ValCys: 0.58 ± 0.026	5.304ValAsp: 5.304 ± 0.073	5.097ValGlu: 5.097 ± 0.077	2.696ValPhe: 2.696 ± 0.062	6.726ValGly: 6.726 ± 0.087	1.88ValHis: 1.88 ± 0.046	4.04ValIle: 4.04 ± 0.071	1.602ValLys: 1.602 ± 0.041	9.763ValLeu: 9.763 ± 0.123	1.745ValMet: 1.745 ± 0.04	1.814ValAsn: 1.814 ± 0.045	4.735ValPro: 4.735 ± 0.066	2.395ValGln: 2.395 ± 0.042	5.688ValArg: 5.688 ± 0.079	4.967ValSer: 4.967 ± 0.08	5.439ValThr: 5.439 ± 0.082	9.05ValVal: 9.05 ± 0.12	1.068ValTrp: 1.068 ± 0.035	1.514ValTyr: 1.514 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.704TrpAla: 1.704 ± 0.043	0.091TrpCys: 0.091 ± 0.01	0.807TrpAsp: 0.807 ± 0.028	0.868TrpGlu: 0.868 ± 0.031	0.576TrpPhe: 0.576 ± 0.027	1.078TrpGly: 1.078 ± 0.034	0.341TrpHis: 0.341 ± 0.018	0.723TrpIle: 0.723 ± 0.027	0.328TrpLys: 0.328 ± 0.019	1.756TrpLeu: 1.756 ± 0.048	0.348TrpMet: 0.348 ± 0.021	0.377TrpAsn: 0.377 ± 0.02	0.703TrpPro: 0.703 ± 0.026	0.59TrpGln: 0.59 ± 0.025	1.163TrpArg: 1.163 ± 0.037	0.929TrpSer: 0.929 ± 0.034	0.899TrpThr: 0.899 ± 0.027	1.241TrpVal: 1.241 ± 0.039	0.373TrpTrp: 0.373 ± 0.022	0.29TrpTyr: 0.29 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.142TyrAla: 2.142 ± 0.052	0.143TyrCys: 0.143 ± 0.012	1.368TyrAsp: 1.368 ± 0.037	1.181TyrGlu: 1.181 ± 0.035	0.708TyrPhe: 0.708 ± 0.027	1.964TyrGly: 1.964 ± 0.05	0.345TyrHis: 0.345 ± 0.018	0.615TyrIle: 0.615 ± 0.025	0.368TyrLys: 0.368 ± 0.021	2.078TyrLeu: 2.078 ± 0.049	0.299TyrMet: 0.299 ± 0.018	0.447TyrAsn: 0.447 ± 0.026	1.074TyrPro: 1.074 ± 0.03	0.639TyrGln: 0.639 ± 0.026	1.635TyrArg: 1.635 ± 0.046	1.073TyrSer: 1.073 ± 0.033	1.089TyrThr: 1.089 ± 0.036	1.608TyrVal: 1.608 ± 0.036	0.329TyrTrp: 0.329 ± 0.02	0.439TyrTyr: 0.439 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2933 proteins (998786 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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