Amino acid dipepetide frequency for Sunxiuqinia dokdonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.257AlaAla: 5.257 ± 0.066	0.741AlaCys: 0.741 ± 0.026	4.247AlaAsp: 4.247 ± 0.07	4.892AlaGlu: 4.892 ± 0.074	3.592AlaPhe: 3.592 ± 0.057	5.426AlaGly: 5.426 ± 0.07	1.247AlaHis: 1.247 ± 0.032	5.108AlaIle: 5.108 ± 0.071	3.972AlaLys: 3.972 ± 0.06	6.493AlaLeu: 6.493 ± 0.086	1.766AlaMet: 1.766 ± 0.035	3.277AlaAsn: 3.277 ± 0.05	2.176AlaPro: 2.176 ± 0.039	2.595AlaGln: 2.595 ± 0.052	2.976AlaArg: 2.976 ± 0.047	4.312AlaSer: 4.312 ± 0.061	3.536AlaThr: 3.536 ± 0.067	4.677AlaVal: 4.677 ± 0.072	0.906AlaTrp: 0.906 ± 0.029	2.657AlaTyr: 2.657 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.506CysAla: 0.506 ± 0.019	0.128CysCys: 0.128 ± 0.01	0.451CysAsp: 0.451 ± 0.018	0.478CysGlu: 0.478 ± 0.018	0.417CysPhe: 0.417 ± 0.016	0.685CysGly: 0.685 ± 0.024	0.25CysHis: 0.25 ± 0.017	0.473CysIle: 0.473 ± 0.023	0.415CysLys: 0.415 ± 0.017	0.757CysLeu: 0.757 ± 0.027	0.208CysMet: 0.208 ± 0.014	0.371CysAsn: 0.371 ± 0.016	0.442CysPro: 0.442 ± 0.02	0.353CysGln: 0.353 ± 0.015	0.392CysArg: 0.392 ± 0.018	0.541CysSer: 0.541 ± 0.023	0.439CysThr: 0.439 ± 0.02	0.418CysVal: 0.418 ± 0.022	0.12CysTrp: 0.12 ± 0.009	0.31CysTyr: 0.31 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.682AspAla: 3.682 ± 0.07	0.449AspCys: 0.449 ± 0.018	3.156AspAsp: 3.156 ± 0.061	4.385AspGlu: 4.385 ± 0.063	3.519AspPhe: 3.519 ± 0.05	4.234AspGly: 4.234 ± 0.078	1.151AspHis: 1.151 ± 0.026	3.503AspIle: 3.503 ± 0.052	3.144AspLys: 3.144 ± 0.05	5.61AspLeu: 5.61 ± 0.069	1.295AspMet: 1.295 ± 0.032	2.385AspAsn: 2.385 ± 0.047	2.263AspPro: 2.263 ± 0.046	2.515AspGln: 2.515 ± 0.044	2.487AspArg: 2.487 ± 0.047	2.969AspSer: 2.969 ± 0.056	2.212AspThr: 2.212 ± 0.044	3.437AspVal: 3.437 ± 0.058	0.926AspTrp: 0.926 ± 0.026	2.718AspTyr: 2.718 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.957GluAla: 4.957 ± 0.074	0.355GluCys: 0.355 ± 0.016	3.268GluAsp: 3.268 ± 0.059	4.792GluGlu: 4.792 ± 0.072	2.904GluPhe: 2.904 ± 0.046	4.009GluGly: 4.009 ± 0.056	1.248GluHis: 1.248 ± 0.031	5.098GluIle: 5.098 ± 0.062	5.694GluLys: 5.694 ± 0.079	6.976GluLeu: 6.976 ± 0.092	2.001GluMet: 2.001 ± 0.041	4.037GluAsn: 4.037 ± 0.055	1.969GluPro: 1.969 ± 0.042	3.041GluGln: 3.041 ± 0.056	2.938GluArg: 2.938 ± 0.052	3.687GluSer: 3.687 ± 0.054	3.582GluThr: 3.582 ± 0.056	4.58GluVal: 4.58 ± 0.058	0.795GluTrp: 0.795 ± 0.029	2.343GluTyr: 2.343 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	3.268PheAla: 3.268 ± 0.055	0.46PheCys: 0.46 ± 0.019	3.317PheAsp: 3.317 ± 0.049	3.459PheGlu: 3.459 ± 0.049	2.856PhePhe: 2.856 ± 0.056	3.558PheGly: 3.558 ± 0.06	1.026PheHis: 1.026 ± 0.025	3.336PheIle: 3.336 ± 0.057	2.769PheLys: 2.769 ± 0.04	4.821PheLeu: 4.821 ± 0.079	1.243PheMet: 1.243 ± 0.036	2.68PheAsn: 2.68 ± 0.046	1.897PhePro: 1.897 ± 0.045	1.929PheGln: 1.929 ± 0.04	2.283PheArg: 2.283 ± 0.043	3.901PheSer: 3.901 ± 0.053	2.573PheThr: 2.573 ± 0.048	3.409PheVal: 3.409 ± 0.048	0.69PheTrp: 0.69 ± 0.023	2.103PheTyr: 2.103 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.47GlyAla: 4.47 ± 0.067	0.675GlyCys: 0.675 ± 0.026	3.534GlyAsp: 3.534 ± 0.059	4.334GlyGlu: 4.334 ± 0.067	3.65GlyPhe: 3.65 ± 0.05	4.79GlyGly: 4.79 ± 0.078	1.278GlyHis: 1.278 ± 0.034	5.295GlyIle: 5.295 ± 0.072	4.779GlyLys: 4.779 ± 0.062	6.439GlyLeu: 6.439 ± 0.077	1.911GlyMet: 1.911 ± 0.042	3.354GlyAsn: 3.354 ± 0.064	1.708GlyPro: 1.708 ± 0.036	2.644GlyGln: 2.644 ± 0.05	2.788GlyArg: 2.788 ± 0.045	4.097GlySer: 4.097 ± 0.061	3.876GlyThr: 3.876 ± 0.062	4.44GlyVal: 4.44 ± 0.066	1.055GlyTrp: 1.055 ± 0.031	2.817GlyTyr: 2.817 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.331HisAla: 1.331 ± 0.034	0.212HisCys: 0.212 ± 0.014	1.02HisAsp: 1.02 ± 0.026	1.27HisGlu: 1.27 ± 0.029	1.258HisPhe: 1.258 ± 0.031	1.317HisGly: 1.317 ± 0.035	0.54HisHis: 0.54 ± 0.023	1.241HisIle: 1.241 ± 0.027	0.952HisLys: 0.952 ± 0.026	2.034HisLeu: 2.034 ± 0.037	0.404HisMet: 0.404 ± 0.015	0.819HisAsn: 0.819 ± 0.026	1.144HisPro: 1.144 ± 0.028	0.951HisGln: 0.951 ± 0.027	0.922HisArg: 0.922 ± 0.029	1.153HisSer: 1.153 ± 0.029	0.911HisThr: 0.911 ± 0.024	1.128HisVal: 1.128 ± 0.03	0.309HisTrp: 0.309 ± 0.015	0.817HisTyr: 0.817 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	4.93IleAla: 4.93 ± 0.06	0.621IleCys: 0.621 ± 0.024	4.381IleAsp: 4.381 ± 0.05	4.806IleGlu: 4.806 ± 0.067	3.211IlePhe: 3.211 ± 0.054	4.661IleGly: 4.661 ± 0.062	1.467IleHis: 1.467 ± 0.034	4.41IleIle: 4.41 ± 0.077	4.095IleLys: 4.095 ± 0.06	6.326IleLeu: 6.326 ± 0.083	1.34IleMet: 1.34 ± 0.032	3.445IleAsn: 3.445 ± 0.052	3.063IlePro: 3.063 ± 0.045	2.682IleGln: 2.682 ± 0.04	3.507IleArg: 3.507 ± 0.054	4.935IleSer: 4.935 ± 0.067	3.664IleThr: 3.664 ± 0.066	4.158IleVal: 4.158 ± 0.065	0.797IleTrp: 0.797 ± 0.028	2.457IleTyr: 2.457 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	4.709LysAla: 4.709 ± 0.06	0.336LysCys: 0.336 ± 0.016	3.42LysAsp: 3.42 ± 0.051	4.754LysGlu: 4.754 ± 0.075	2.364LysPhe: 2.364 ± 0.042	3.876LysGly: 3.876 ± 0.055	1.295LysHis: 1.295 ± 0.03	4.789LysIle: 4.789 ± 0.066	5.056LysLys: 5.056 ± 0.081	6.236LysLeu: 6.236 ± 0.074	1.901LysMet: 1.901 ± 0.038	3.739LysAsn: 3.739 ± 0.05	2.415LysPro: 2.415 ± 0.046	2.719LysGln: 2.719 ± 0.049	3.0LysArg: 3.0 ± 0.05	3.771LysSer: 3.771 ± 0.063	3.743LysThr: 3.743 ± 0.051	4.031LysVal: 4.031 ± 0.058	0.745LysTrp: 0.745 ± 0.025	2.437LysTyr: 2.437 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	7.106LeuAla: 7.106 ± 0.091	0.718LeuCys: 0.718 ± 0.023	5.173LeuAsp: 5.173 ± 0.062	6.15LeuGlu: 6.15 ± 0.072	5.276LeuPhe: 5.276 ± 0.067	5.872LeuGly: 5.872 ± 0.063	1.729LeuHis: 1.729 ± 0.035	6.749LeuIle: 6.749 ± 0.091	7.152LeuLys: 7.152 ± 0.09	9.421LeuLeu: 9.421 ± 0.114	2.393LeuMet: 2.393 ± 0.043	5.105LeuAsn: 5.105 ± 0.062	4.071LeuPro: 4.071 ± 0.054	3.458LeuGln: 3.458 ± 0.052	3.768LeuArg: 3.768 ± 0.055	6.713LeuSer: 6.713 ± 0.069	5.118LeuThr: 5.118 ± 0.067	6.401LeuVal: 6.401 ± 0.074	0.957LeuTrp: 0.957 ± 0.028	3.087LeuTyr: 3.087 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	1.988MetAla: 1.988 ± 0.039	0.139MetCys: 0.139 ± 0.01	1.367MetAsp: 1.367 ± 0.034	1.689MetGlu: 1.689 ± 0.037	0.85MetPhe: 0.85 ± 0.024	1.682MetGly: 1.682 ± 0.04	0.444MetHis: 0.444 ± 0.017	1.689MetIle: 1.689 ± 0.039	2.35MetLys: 2.35 ± 0.041	2.238MetLeu: 2.238 ± 0.042	0.719MetMet: 0.719 ± 0.026	1.48MetAsn: 1.48 ± 0.035	1.035MetPro: 1.035 ± 0.026	0.917MetGln: 0.917 ± 0.027	1.008MetArg: 1.008 ± 0.024	1.298MetSer: 1.298 ± 0.033	1.374MetThr: 1.374 ± 0.034	1.609MetVal: 1.609 ± 0.034	0.216MetTrp: 0.216 ± 0.01	0.653MetTyr: 0.653 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.048AsnAla: 3.048 ± 0.05	0.449AsnCys: 0.449 ± 0.02	2.644AsnAsp: 2.644 ± 0.042	3.415AsnGlu: 3.415 ± 0.059	2.582AsnPhe: 2.582 ± 0.045	3.515AsnGly: 3.515 ± 0.066	1.116AsnHis: 1.116 ± 0.028	3.365AsnIle: 3.365 ± 0.053	3.113AsnLys: 3.113 ± 0.046	4.967AsnLeu: 4.967 ± 0.06	1.221AsnMet: 1.221 ± 0.029	2.54AsnAsn: 2.54 ± 0.039	2.63AsnPro: 2.63 ± 0.047	2.382AsnGln: 2.382 ± 0.045	2.521AsnArg: 2.521 ± 0.043	2.998AsnSer: 2.998 ± 0.053	2.531AsnThr: 2.531 ± 0.053	2.609AsnVal: 2.609 ± 0.05	0.783AsnTrp: 0.783 ± 0.03	2.458AsnTyr: 2.458 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	2.974ProAla: 2.974 ± 0.049	0.23ProCys: 0.23 ± 0.014	2.773ProAsp: 2.773 ± 0.042	3.573ProGlu: 3.573 ± 0.051	1.974ProPhe: 1.974 ± 0.04	2.769ProGly: 2.769 ± 0.046	0.729ProHis: 0.729 ± 0.022	2.34ProIle: 2.34 ± 0.041	2.116ProLys: 2.116 ± 0.046	3.207ProLeu: 3.207 ± 0.05	0.879ProMet: 0.879 ± 0.026	1.826ProAsn: 1.826 ± 0.033	1.012ProPro: 1.012 ± 0.032	1.3ProGln: 1.3 ± 0.031	1.287ProArg: 1.287 ± 0.035	2.155ProSer: 2.155 ± 0.046	1.84ProThr: 1.84 ± 0.045	3.248ProVal: 3.248 ± 0.049	0.461ProTrp: 0.461 ± 0.019	1.393ProTyr: 1.393 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.125GlnAla: 3.125 ± 0.054	0.204GlnCys: 0.204 ± 0.012	1.784GlnAsp: 1.784 ± 0.034	2.555GlnGlu: 2.555 ± 0.042	1.936GlnPhe: 1.936 ± 0.041	2.157GlnGly: 2.157 ± 0.042	0.793GlnHis: 0.793 ± 0.02	2.795GlnIle: 2.795 ± 0.043	2.86GlnLys: 2.86 ± 0.052	4.385GlnLeu: 4.385 ± 0.067	0.997GlnMet: 0.997 ± 0.026	2.062GlnAsn: 2.062 ± 0.04	1.417GlnPro: 1.417 ± 0.034	2.05GlnGln: 2.05 ± 0.05	1.704GlnArg: 1.704 ± 0.038	2.299GlnSer: 2.299 ± 0.042	2.234GlnThr: 2.234 ± 0.046	2.827GlnVal: 2.827 ± 0.045	0.461GlnTrp: 0.461 ± 0.018	1.397GlnTyr: 1.397 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.526ArgAla: 2.526 ± 0.044	0.314ArgCys: 0.314 ± 0.017	2.176ArgAsp: 2.176 ± 0.043	3.035ArgGlu: 3.035 ± 0.046	2.494ArgPhe: 2.494 ± 0.043	2.419ArgGly: 2.419 ± 0.047	0.858ArgHis: 0.858 ± 0.028	3.404ArgIle: 3.404 ± 0.05	3.245ArgLys: 3.245 ± 0.059	4.386ArgLeu: 4.386 ± 0.06	1.289ArgMet: 1.289 ± 0.028	2.361ArgAsn: 2.361 ± 0.04	1.461ArgPro: 1.461 ± 0.035	1.923ArgGln: 1.923 ± 0.037	1.958ArgArg: 1.958 ± 0.039	2.472ArgSer: 2.472 ± 0.045	2.142ArgThr: 2.142 ± 0.035	2.644ArgVal: 2.644 ± 0.051	0.65ArgTrp: 0.65 ± 0.022	1.87ArgTyr: 1.87 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	4.143SerAla: 4.143 ± 0.055	0.631SerCys: 0.631 ± 0.025	3.438SerAsp: 3.438 ± 0.058	3.994SerGlu: 3.994 ± 0.054	3.686SerPhe: 3.686 ± 0.052	4.922SerGly: 4.922 ± 0.068	1.204SerHis: 1.204 ± 0.029	4.175SerIle: 4.175 ± 0.058	3.763SerLys: 3.763 ± 0.055	6.075SerLeu: 6.075 ± 0.068	1.514SerMet: 1.514 ± 0.031	2.876SerAsn: 2.876 ± 0.046	2.476SerPro: 2.476 ± 0.047	2.249SerGln: 2.249 ± 0.044	2.734SerArg: 2.734 ± 0.045	4.109SerSer: 4.109 ± 0.074	3.061SerThr: 3.061 ± 0.053	4.01SerVal: 4.01 ± 0.052	0.882SerTrp: 0.882 ± 0.029	2.614SerTyr: 2.614 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	3.816ThrAla: 3.816 ± 0.073	0.384ThrCys: 0.384 ± 0.018	3.089ThrAsp: 3.089 ± 0.054	3.124ThrGlu: 3.124 ± 0.051	2.481ThrPhe: 2.481 ± 0.045	4.342ThrGly: 4.342 ± 0.062	0.944ThrHis: 0.944 ± 0.026	3.965ThrIle: 3.965 ± 0.055	2.937ThrLys: 2.937 ± 0.05	4.582ThrLeu: 4.582 ± 0.064	1.045ThrMet: 1.045 ± 0.025	2.584ThrAsn: 2.584 ± 0.049	2.332ThrPro: 2.332 ± 0.043	1.766ThrGln: 1.766 ± 0.031	2.051ThrArg: 2.051 ± 0.035	3.252ThrSer: 3.252 ± 0.05	2.87ThrThr: 2.87 ± 0.06	3.468ThrVal: 3.468 ± 0.065	0.553ThrTrp: 0.553 ± 0.022	2.043ThrTyr: 2.043 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	4.697ValAla: 4.697 ± 0.053	0.635ValCys: 0.635 ± 0.023	3.833ValAsp: 3.833 ± 0.053	4.377ValGlu: 4.377 ± 0.062	3.483ValPhe: 3.483 ± 0.049	4.121ValGly: 4.121 ± 0.052	1.214ValHis: 1.214 ± 0.032	4.332ValIle: 4.332 ± 0.058	3.928ValLys: 3.928 ± 0.057	6.226ValLeu: 6.226 ± 0.07	1.501ValMet: 1.501 ± 0.037	3.285ValAsn: 3.285 ± 0.052	2.569ValPro: 2.569 ± 0.046	2.124ValGln: 2.124 ± 0.04	2.716ValArg: 2.716 ± 0.037	4.495ValSer: 4.495 ± 0.059	3.22ValThr: 3.22 ± 0.062	4.666ValVal: 4.666 ± 0.069	0.768ValTrp: 0.768 ± 0.022	2.372ValTyr: 2.372 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.84TrpAla: 0.84 ± 0.027	0.121TrpCys: 0.121 ± 0.01	0.773TrpAsp: 0.773 ± 0.024	0.869TrpGlu: 0.869 ± 0.03	0.629TrpPhe: 0.629 ± 0.022	0.956TrpGly: 0.956 ± 0.033	0.288TrpHis: 0.288 ± 0.014	0.829TrpIle: 0.829 ± 0.027	0.845TrpLys: 0.845 ± 0.024	1.239TrpLeu: 1.239 ± 0.033	0.354TrpMet: 0.354 ± 0.017	0.734TrpAsn: 0.734 ± 0.025	0.383TrpPro: 0.383 ± 0.016	0.551TrpGln: 0.551 ± 0.019	0.573TrpArg: 0.573 ± 0.018	0.771TrpSer: 0.771 ± 0.022	0.679TrpThr: 0.679 ± 0.025	0.748TrpVal: 0.748 ± 0.022	0.204TrpTrp: 0.204 ± 0.012	0.465TrpTyr: 0.465 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.479TyrAla: 2.479 ± 0.041	0.354TyrCys: 0.354 ± 0.014	2.2TyrAsp: 2.2 ± 0.043	2.324TyrGlu: 2.324 ± 0.043	2.415TyrPhe: 2.415 ± 0.041	2.621TyrGly: 2.621 ± 0.053	0.911TyrHis: 0.911 ± 0.026	2.06TyrIle: 2.06 ± 0.042	2.15TyrLys: 2.15 ± 0.045	4.001TyrLeu: 4.001 ± 0.062	0.763TyrMet: 0.763 ± 0.022	1.93TyrAsn: 1.93 ± 0.044	1.621TyrPro: 1.621 ± 0.034	1.893TyrGln: 1.893 ± 0.038	2.014TyrArg: 2.014 ± 0.031	2.625TyrSer: 2.625 ± 0.056	2.023TyrThr: 2.023 ± 0.048	2.055TyrVal: 2.055 ± 0.035	0.571TyrTrp: 0.571 ± 0.022	1.726TyrTyr: 1.726 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4693 proteins (1442061 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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