Amino acid dipepetide frequency for Selenomonas ruminantium

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.734AlaAla: 10.734 ± 0.165	1.196AlaCys: 1.196 ± 0.046	5.625AlaAsp: 5.625 ± 0.083	7.194AlaGlu: 7.194 ± 0.106	3.352AlaPhe: 3.352 ± 0.077	7.718AlaGly: 7.718 ± 0.098	1.619AlaHis: 1.619 ± 0.039	5.636AlaIle: 5.636 ± 0.096	5.996AlaLys: 5.996 ± 0.096	8.297AlaLeu: 8.297 ± 0.115	3.125AlaMet: 3.125 ± 0.067	3.034AlaAsn: 3.034 ± 0.077	2.754AlaPro: 2.754 ± 0.07	3.508AlaGln: 3.508 ± 0.072	4.145AlaArg: 4.145 ± 0.075	4.408AlaSer: 4.408 ± 0.087	3.728AlaThr: 3.728 ± 0.08	7.299AlaVal: 7.299 ± 0.1	0.809AlaTrp: 0.809 ± 0.034	2.92AlaTyr: 2.92 ± 0.066	0.0AlaXaa: 0.0 ± 0.0
Cys	0.986CysAla: 0.986 ± 0.04	0.237CysCys: 0.237 ± 0.019	0.664CysAsp: 0.664 ± 0.03	0.669CysGlu: 0.669 ± 0.029	0.512CysPhe: 0.512 ± 0.023	1.287CysGly: 1.287 ± 0.05	0.309CysHis: 0.309 ± 0.022	0.727CysIle: 0.727 ± 0.029	0.644CysLys: 0.644 ± 0.031	1.238CysLeu: 1.238 ± 0.042	0.352CysMet: 0.352 ± 0.022	0.419CysAsn: 0.419 ± 0.024	0.638CysPro: 0.638 ± 0.032	0.497CysGln: 0.497 ± 0.024	0.723CysArg: 0.723 ± 0.028	0.671CysSer: 0.671 ± 0.033	0.562CysThr: 0.562 ± 0.029	0.824CysVal: 0.824 ± 0.032	0.14CysTrp: 0.14 ± 0.013	0.491CysTyr: 0.491 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	4.546AspAla: 4.546 ± 0.072	0.693AspCys: 0.693 ± 0.031	2.923AspAsp: 2.923 ± 0.074	4.442AspGlu: 4.442 ± 0.085	2.724AspPhe: 2.724 ± 0.068	4.452AspGly: 4.452 ± 0.088	0.86AspHis: 0.86 ± 0.038	4.242AspIle: 4.242 ± 0.08	4.166AspLys: 4.166 ± 0.086	4.362AspLeu: 4.362 ± 0.08	2.044AspMet: 2.044 ± 0.053	2.157AspAsn: 2.157 ± 0.062	1.592AspPro: 1.592 ± 0.048	1.02AspGln: 1.02 ± 0.034	2.243AspArg: 2.243 ± 0.052	2.782AspSer: 2.782 ± 0.061	2.842AspThr: 2.842 ± 0.072	4.16AspVal: 4.16 ± 0.079	0.724AspTrp: 0.724 ± 0.03	2.548AspTyr: 2.548 ± 0.061	0.0AspXaa: 0.0 ± 0.0
Glu	6.631GluAla: 6.631 ± 0.116	0.698GluCys: 0.698 ± 0.031	3.741GluAsp: 3.741 ± 0.076	5.655GluGlu: 5.655 ± 0.095	2.469GluPhe: 2.469 ± 0.059	4.213GluGly: 4.213 ± 0.076	1.411GluHis: 1.411 ± 0.043	4.759GluIle: 4.759 ± 0.083	5.527GluLys: 5.527 ± 0.085	7.063GluLeu: 7.063 ± 0.103	2.359GluMet: 2.359 ± 0.05	3.304GluAsn: 3.304 ± 0.069	2.023GluPro: 2.023 ± 0.061	2.958GluGln: 2.958 ± 0.073	3.634GluArg: 3.634 ± 0.073	3.044GluSer: 3.044 ± 0.063	3.129GluThr: 3.129 ± 0.055	4.568GluVal: 4.568 ± 0.083	0.627GluTrp: 0.627 ± 0.029	2.262GluTyr: 2.262 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	3.883PheAla: 3.883 ± 0.076	0.641PheCys: 0.641 ± 0.031	2.339PheAsp: 2.339 ± 0.05	1.839PheGlu: 1.839 ± 0.051	1.907PhePhe: 1.907 ± 0.055	3.017PheGly: 3.017 ± 0.072	0.861PheHis: 0.861 ± 0.036	2.679PheIle: 2.679 ± 0.06	1.787PheLys: 1.787 ± 0.054	3.773PheLeu: 3.773 ± 0.086	1.341PheMet: 1.341 ± 0.035	1.427PheAsn: 1.427 ± 0.04	1.356PhePro: 1.356 ± 0.044	1.258PheGln: 1.258 ± 0.038	1.605PheArg: 1.605 ± 0.05	2.482PheSer: 2.482 ± 0.057	2.239PheThr: 2.239 ± 0.055	2.837PheVal: 2.837 ± 0.069	0.53PheTrp: 0.53 ± 0.023	1.485PheTyr: 1.485 ± 0.049	0.0PheXaa: 0.0 ± 0.0
Gly	6.177GlyAla: 6.177 ± 0.102	1.092GlyCys: 1.092 ± 0.04	3.681GlyAsp: 3.681 ± 0.074	4.772GlyGlu: 4.772 ± 0.084	3.176GlyPhe: 3.176 ± 0.067	5.433GlyGly: 5.433 ± 0.107	1.608GlyHis: 1.608 ± 0.045	5.611GlyIle: 5.611 ± 0.096	5.399GlyLys: 5.399 ± 0.093	6.684GlyLeu: 6.684 ± 0.088	2.635GlyMet: 2.635 ± 0.066	2.783GlyAsn: 2.783 ± 0.077	1.52GlyPro: 1.52 ± 0.04	2.66GlyGln: 2.66 ± 0.064	3.844GlyArg: 3.844 ± 0.065	4.072GlySer: 4.072 ± 0.08	4.322GlyThr: 4.322 ± 0.099	5.343GlyVal: 5.343 ± 0.088	0.975GlyTrp: 0.975 ± 0.036	2.73GlyTyr: 2.73 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.444HisAla: 1.444 ± 0.046	0.323HisCys: 0.323 ± 0.02	1.12HisAsp: 1.12 ± 0.038	1.364HisGlu: 1.364 ± 0.038	0.938HisPhe: 0.938 ± 0.037	1.583HisGly: 1.583 ± 0.047	0.518HisHis: 0.518 ± 0.025	1.399HisIle: 1.399 ± 0.044	1.11HisLys: 1.11 ± 0.035	1.796HisLeu: 1.796 ± 0.051	0.542HisMet: 0.542 ± 0.025	0.797HisAsn: 0.797 ± 0.031	1.056HisPro: 1.056 ± 0.043	0.613HisGln: 0.613 ± 0.029	0.985HisArg: 0.985 ± 0.032	1.02HisSer: 1.02 ± 0.036	1.11HisThr: 1.11 ± 0.037	1.313HisVal: 1.313 ± 0.041	0.232HisTrp: 0.232 ± 0.016	0.81HisTyr: 0.81 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	6.155IleAla: 6.155 ± 0.097	0.994IleCys: 0.994 ± 0.037	3.725IleAsp: 3.725 ± 0.078	3.965IleGlu: 3.965 ± 0.078	2.596IlePhe: 2.596 ± 0.067	4.886IleGly: 4.886 ± 0.1	1.33IleHis: 1.33 ± 0.042	4.215IleIle: 4.215 ± 0.086	3.702IleLys: 3.702 ± 0.065	5.802IleLeu: 5.802 ± 0.095	1.945IleMet: 1.945 ± 0.054	2.616IleAsn: 2.616 ± 0.07	2.707IlePro: 2.707 ± 0.075	1.93IleGln: 1.93 ± 0.053	3.051IleArg: 3.051 ± 0.061	3.721IleSer: 3.721 ± 0.074	3.67IleThr: 3.67 ± 0.066	4.512IleVal: 4.512 ± 0.081	0.578IleTrp: 0.578 ± 0.031	2.149IleTyr: 2.149 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	5.876LysAla: 5.876 ± 0.096	0.591LysCys: 0.591 ± 0.026	3.631LysAsp: 3.631 ± 0.065	5.069LysGlu: 5.069 ± 0.084	2.11LysPhe: 2.11 ± 0.048	4.018LysGly: 4.018 ± 0.075	1.111LysHis: 1.111 ± 0.042	4.091LysIle: 4.091 ± 0.078	4.675LysLys: 4.675 ± 0.085	5.932LysLeu: 5.932 ± 0.089	2.158LysMet: 2.158 ± 0.048	2.906LysAsn: 2.906 ± 0.072	2.087LysPro: 2.087 ± 0.054	2.249LysGln: 2.249 ± 0.057	2.873LysArg: 2.873 ± 0.059	2.839LysSer: 2.839 ± 0.061	3.054LysThr: 3.054 ± 0.059	4.433LysVal: 4.433 ± 0.076	0.65LysTrp: 0.65 ± 0.027	2.158LysTyr: 2.158 ± 0.059	0.0LysXaa: 0.0 ± 0.0
Leu	9.532LeuAla: 9.532 ± 0.138	1.324LeuCys: 1.324 ± 0.039	5.058LeuAsp: 5.058 ± 0.089	5.537LeuGlu: 5.537 ± 0.084	3.445LeuPhe: 3.445 ± 0.075	6.969LeuGly: 6.969 ± 0.103	1.944LeuHis: 1.944 ± 0.052	5.074LeuIle: 5.074 ± 0.09	5.38LeuLys: 5.38 ± 0.088	9.731LeuLeu: 9.731 ± 0.175	2.735LeuMet: 2.735 ± 0.058	3.474LeuAsn: 3.474 ± 0.067	4.591LeuPro: 4.591 ± 0.084	3.958LeuGln: 3.958 ± 0.076	4.552LeuArg: 4.552 ± 0.078	5.738LeuSer: 5.738 ± 0.083	5.767LeuThr: 5.767 ± 0.102	6.204LeuVal: 6.204 ± 0.112	0.939LeuTrp: 0.939 ± 0.036	2.916LeuTyr: 2.916 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	3.356MetAla: 3.356 ± 0.07	0.268MetCys: 0.268 ± 0.018	1.992MetAsp: 1.992 ± 0.044	2.453MetGlu: 2.453 ± 0.05	1.018MetPhe: 1.018 ± 0.038	2.387MetGly: 2.387 ± 0.053	0.542MetHis: 0.542 ± 0.024	1.575MetIle: 1.575 ± 0.049	2.036MetLys: 2.036 ± 0.051	3.158MetLeu: 3.158 ± 0.072	1.029MetMet: 1.029 ± 0.037	1.308MetAsn: 1.308 ± 0.034	1.43MetPro: 1.43 ± 0.042	1.381MetGln: 1.381 ± 0.043	1.434MetArg: 1.434 ± 0.046	1.836MetSer: 1.836 ± 0.051	1.797MetThr: 1.797 ± 0.058	2.297MetVal: 2.297 ± 0.054	0.199MetTrp: 0.199 ± 0.015	0.741MetTyr: 0.741 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.202AsnAla: 3.202 ± 0.071	0.516AsnCys: 0.516 ± 0.029	1.967AsnAsp: 1.967 ± 0.055	2.314AsnGlu: 2.314 ± 0.054	1.672AsnPhe: 1.672 ± 0.047	3.094AsnGly: 3.094 ± 0.081	0.826AsnHis: 0.826 ± 0.033	2.998AsnIle: 2.998 ± 0.062	2.198AsnLys: 2.198 ± 0.06	3.65AsnLeu: 3.65 ± 0.073	1.325AsnMet: 1.325 ± 0.038	1.543AsnAsn: 1.543 ± 0.054	1.981AsnPro: 1.981 ± 0.052	1.173AsnGln: 1.173 ± 0.041	1.811AsnArg: 1.811 ± 0.047	1.871AsnSer: 1.871 ± 0.065	1.902AsnThr: 1.902 ± 0.067	2.935AsnVal: 2.935 ± 0.072	0.432AsnTrp: 0.432 ± 0.026	1.503AsnTyr: 1.503 ± 0.061	0.0AsnXaa: 0.0 ± 0.0
Pro	3.607ProAla: 3.607 ± 0.076	0.45ProCys: 0.45 ± 0.029	2.279ProAsp: 2.279 ± 0.059	3.358ProGlu: 3.358 ± 0.076	1.566ProPhe: 1.566 ± 0.052	2.492ProGly: 2.492 ± 0.069	0.796ProHis: 0.796 ± 0.034	2.092ProIle: 2.092 ± 0.049	1.945ProLys: 1.945 ± 0.057	3.528ProLeu: 3.528 ± 0.076	1.041ProMet: 1.041 ± 0.036	1.261ProAsn: 1.261 ± 0.031	1.108ProPro: 1.108 ± 0.045	1.683ProGln: 1.683 ± 0.05	1.398ProArg: 1.398 ± 0.042	1.634ProSer: 1.634 ± 0.044	1.68ProThr: 1.68 ± 0.047	3.195ProVal: 3.195 ± 0.075	0.414ProTrp: 0.414 ± 0.024	1.293ProTyr: 1.293 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	3.789GlnAla: 3.789 ± 0.073	0.297GlnCys: 0.297 ± 0.02	1.98GlnAsp: 1.98 ± 0.051	3.32GlnGlu: 3.32 ± 0.062	1.099GlnPhe: 1.099 ± 0.037	2.645GlnGly: 2.645 ± 0.06	0.704GlnHis: 0.704 ± 0.029	2.128GlnIle: 2.128 ± 0.055	2.549GlnLys: 2.549 ± 0.07	3.43GlnLeu: 3.43 ± 0.073	1.215GlnMet: 1.215 ± 0.042	1.549GlnAsn: 1.549 ± 0.053	1.375GlnPro: 1.375 ± 0.045	1.98GlnGln: 1.98 ± 0.062	1.956GlnArg: 1.956 ± 0.054	1.787GlnSer: 1.787 ± 0.057	1.662GlnThr: 1.662 ± 0.051	2.569GlnVal: 2.569 ± 0.054	0.323GlnTrp: 0.323 ± 0.022	1.128GlnTyr: 1.128 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	3.436ArgAla: 3.436 ± 0.062	0.512ArgCys: 0.512 ± 0.027	2.458ArgAsp: 2.458 ± 0.06	3.858ArgGlu: 3.858 ± 0.073	1.798ArgPhe: 1.798 ± 0.038	2.97ArgGly: 2.97 ± 0.055	1.06ArgHis: 1.06 ± 0.035	3.263ArgIle: 3.263 ± 0.064	3.101ArgLys: 3.101 ± 0.062	4.74ArgLeu: 4.74 ± 0.093	1.628ArgMet: 1.628 ± 0.044	1.888ArgAsn: 1.888 ± 0.054	1.745ArgPro: 1.745 ± 0.051	2.555ArgGln: 2.555 ± 0.068	2.667ArgArg: 2.667 ± 0.065	2.223ArgSer: 2.223 ± 0.059	2.286ArgThr: 2.286 ± 0.053	2.911ArgVal: 2.911 ± 0.066	0.517ArgTrp: 0.517 ± 0.027	1.824ArgTyr: 1.824 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	4.608SerAla: 4.608 ± 0.082	0.661SerCys: 0.661 ± 0.034	2.663SerAsp: 2.663 ± 0.057	3.055SerGlu: 3.055 ± 0.065	2.37SerPhe: 2.37 ± 0.063	4.34SerGly: 4.34 ± 0.095	1.137SerHis: 1.137 ± 0.037	3.343SerIle: 3.343 ± 0.071	2.789SerLys: 2.789 ± 0.066	5.264SerLeu: 5.264 ± 0.084	1.747SerMet: 1.747 ± 0.047	1.843SerAsn: 1.843 ± 0.056	1.906SerPro: 1.906 ± 0.052	1.91SerGln: 1.91 ± 0.053	2.687SerArg: 2.687 ± 0.058	2.912SerSer: 2.912 ± 0.073	2.488SerThr: 2.488 ± 0.061	3.713SerVal: 3.713 ± 0.079	0.625SerTrp: 0.625 ± 0.029	1.966SerTyr: 1.966 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.324ThrAla: 5.324 ± 0.101	0.619ThrCys: 0.619 ± 0.031	2.877ThrAsp: 2.877 ± 0.074	3.295ThrGlu: 3.295 ± 0.061	1.882ThrPhe: 1.882 ± 0.048	4.708ThrGly: 4.708 ± 0.107	0.914ThrHis: 0.914 ± 0.032	3.334ThrIle: 3.334 ± 0.079	2.627ThrLys: 2.627 ± 0.062	4.896ThrLeu: 4.896 ± 0.092	1.501ThrMet: 1.501 ± 0.042	1.835ThrAsn: 1.835 ± 0.065	2.259ThrPro: 2.259 ± 0.051	1.524ThrGln: 1.524 ± 0.044	2.067ThrArg: 2.067 ± 0.052	2.655ThrSer: 2.655 ± 0.065	2.605ThrThr: 2.605 ± 0.072	4.251ThrVal: 4.251 ± 0.082	0.514ThrTrp: 0.514 ± 0.03	1.678ThrTyr: 1.678 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	6.255ValAla: 6.255 ± 0.097	0.892ValCys: 0.892 ± 0.04	4.139ValAsp: 4.139 ± 0.08	4.915ValGlu: 4.915 ± 0.092	2.757ValPhe: 2.757 ± 0.066	4.777ValGly: 4.777 ± 0.091	1.352ValHis: 1.352 ± 0.046	4.537ValIle: 4.537 ± 0.095	4.495ValLys: 4.495 ± 0.087	7.076ValLeu: 7.076 ± 0.112	2.212ValMet: 2.212 ± 0.049	2.844ValAsn: 2.844 ± 0.061	2.981ValPro: 2.981 ± 0.058	2.453ValGln: 2.453 ± 0.062	3.415ValArg: 3.415 ± 0.06	4.018ValSer: 4.018 ± 0.074	4.213ValThr: 4.213 ± 0.09	5.348ValVal: 5.348 ± 0.093	0.692ValTrp: 0.692 ± 0.032	2.36ValTyr: 2.36 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.719TrpAla: 0.719 ± 0.025	0.142TrpCys: 0.142 ± 0.011	0.483TrpAsp: 0.483 ± 0.024	0.711TrpGlu: 0.711 ± 0.03	0.393TrpPhe: 0.393 ± 0.022	0.76TrpGly: 0.76 ± 0.032	0.322TrpHis: 0.322 ± 0.02	0.513TrpIle: 0.513 ± 0.027	0.554TrpLys: 0.554 ± 0.024	1.253TrpLeu: 1.253 ± 0.043	0.319TrpMet: 0.319 ± 0.022	0.511TrpAsn: 0.511 ± 0.03	0.32TrpPro: 0.32 ± 0.018	0.838TrpGln: 0.838 ± 0.038	0.575TrpArg: 0.575 ± 0.025	0.522TrpSer: 0.522 ± 0.026	0.425TrpThr: 0.425 ± 0.025	0.565TrpVal: 0.565 ± 0.027	0.147TrpTrp: 0.147 ± 0.013	0.371TrpTyr: 0.371 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.838TyrAla: 2.838 ± 0.053	0.445TyrCys: 0.445 ± 0.022	2.179TyrAsp: 2.179 ± 0.065	2.286TyrGlu: 2.286 ± 0.057	1.503TyrPhe: 1.503 ± 0.047	2.77TyrGly: 2.77 ± 0.062	0.849TyrHis: 0.849 ± 0.036	2.035TyrIle: 2.035 ± 0.056	1.833TyrLys: 1.833 ± 0.048	3.193TyrLeu: 3.193 ± 0.065	0.983TyrMet: 0.983 ± 0.035	1.416TyrAsn: 1.416 ± 0.05	1.39TyrPro: 1.39 ± 0.052	1.336TyrGln: 1.336 ± 0.038	1.773TyrArg: 1.773 ± 0.048	1.792TyrSer: 1.792 ± 0.047	1.883TyrThr: 1.883 ± 0.064	2.452TyrVal: 2.452 ± 0.058	0.377TyrTrp: 0.377 ± 0.021	1.418TyrTyr: 1.418 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2579 proteins (824202 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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