Amino acid dipepetide frequency for Capsicum annuum amalgavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.267AlaAla: 6.267 ± 0.919
0.0AlaCys: 0.0 ± 0.0
4.178AlaAsp: 4.178 ± 2.021
5.571AlaGlu: 5.571 ± 1.286
2.786AlaPhe: 2.786 ± 1.347
6.964AlaGly: 6.964 ± 1.96
2.786AlaHis: 2.786 ± 1.347
6.267AlaIle: 6.267 ± 0.919
4.178AlaLys: 4.178 ± 2.021
8.357AlaLeu: 8.357 ± 2.998
2.089AlaMet: 2.089 ± 0.306
1.393AlaAsn: 1.393 ± 0.734
1.393AlaPro: 1.393 ± 0.734
1.393AlaGln: 1.393 ± 0.674
8.357AlaArg: 8.357 ± 1.225
5.571AlaSer: 5.571 ± 1.529
3.482AlaThr: 3.482 ± 0.428
2.786AlaVal: 2.786 ± 0.061
0.696AlaTrp: 0.696 ± 0.367
2.786AlaTyr: 2.786 ± 1.469
0.0AlaXaa: 0.0 ± 0.0
Cys
1.393CysAla: 1.393 ± 0.734
0.0CysCys: 0.0 ± 0.0
0.696CysAsp: 0.696 ± 0.367
0.0CysGlu: 0.0 ± 0.0
1.393CysPhe: 1.393 ± 0.734
0.696CysGly: 0.696 ± 0.367
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.393CysLys: 1.393 ± 0.734
0.0CysLeu: 0.0 ± 0.0
0.696CysMet: 0.696 ± 0.367
0.0CysAsn: 0.0 ± 0.0
0.696CysPro: 0.696 ± 0.367
0.0CysGln: 0.0 ± 0.0
0.696CysArg: 0.696 ± 0.367
0.696CysSer: 0.696 ± 0.367
0.0CysThr: 0.0 ± 0.0
1.393CysVal: 1.393 ± 0.734
1.393CysTrp: 1.393 ± 0.674
1.393CysTyr: 1.393 ± 0.734
0.0CysXaa: 0.0 ± 0.0
Asp
6.267AspAla: 6.267 ± 0.919
0.0AspCys: 0.0 ± 0.0
2.089AspAsp: 2.089 ± 1.101
12.535AspGlu: 12.535 ± 1.838
2.089AspPhe: 2.089 ± 0.306
2.089AspGly: 2.089 ± 0.306
2.786AspHis: 2.786 ± 0.061
2.089AspIle: 2.089 ± 1.101
2.786AspLys: 2.786 ± 1.347
6.267AspLeu: 6.267 ± 0.489
0.696AspMet: 0.696 ± 0.367
2.786AspAsn: 2.786 ± 1.469
1.393AspPro: 1.393 ± 0.674
2.089AspGln: 2.089 ± 0.306
1.393AspArg: 1.393 ± 0.734
2.089AspSer: 2.089 ± 0.306
2.089AspThr: 2.089 ± 0.306
4.875AspVal: 4.875 ± 1.653
2.786AspTrp: 2.786 ± 0.061
0.696AspTyr: 0.696 ± 0.367
0.0AspXaa: 0.0 ± 0.0
Glu
6.267GluAla: 6.267 ± 0.919
1.393GluCys: 1.393 ± 0.734
4.178GluAsp: 4.178 ± 0.795
2.786GluGlu: 2.786 ± 1.347
2.089GluPhe: 2.089 ± 1.101
5.571GluGly: 5.571 ± 4.102
1.393GluHis: 1.393 ± 0.674
9.053GluIle: 9.053 ± 2.266
4.875GluLys: 4.875 ± 0.246
6.964GluLeu: 6.964 ± 1.96
1.393GluMet: 1.393 ± 0.734
1.393GluAsn: 1.393 ± 0.734
2.089GluPro: 2.089 ± 1.714
2.089GluGln: 2.089 ± 0.306
3.482GluArg: 3.482 ± 0.428
0.696GluSer: 0.696 ± 0.367
0.696GluThr: 0.696 ± 0.367
9.053GluVal: 9.053 ± 0.858
1.393GluTrp: 1.393 ± 0.734
4.875GluTyr: 4.875 ± 0.246
0.0GluXaa: 0.0 ± 0.0
Phe
2.089PheAla: 2.089 ± 1.101
0.0PheCys: 0.0 ± 0.0
6.267PheAsp: 6.267 ± 2.327
2.089PheGlu: 2.089 ± 1.101
3.482PhePhe: 3.482 ± 0.98
1.393PheGly: 1.393 ± 0.674
0.0PheHis: 0.0 ± 0.0
1.393PheIle: 1.393 ± 0.674
2.089PheLys: 2.089 ± 0.306
2.786PheLeu: 2.786 ± 0.061
0.696PheMet: 0.696 ± 0.367
2.786PheAsn: 2.786 ± 1.469
1.393PhePro: 1.393 ± 0.734
0.0PheGln: 0.0 ± 0.0
3.482PheArg: 3.482 ± 0.428
2.786PheSer: 2.786 ± 0.061
2.089PheThr: 2.089 ± 0.306
2.089PheVal: 2.089 ± 1.101
0.0PheTrp: 0.0 ± 0.0
0.696PheTyr: 0.696 ± 0.367
0.0PheXaa: 0.0 ± 0.0
Gly
2.089GlyAla: 2.089 ± 1.101
2.089GlyCys: 2.089 ± 1.101
7.66GlyAsp: 7.66 ± 3.0
4.875GlyGlu: 4.875 ± 3.061
0.696GlyPhe: 0.696 ± 0.367
9.053GlyGly: 9.053 ± 0.55
3.482GlyHis: 3.482 ± 2.388
4.178GlyIle: 4.178 ± 0.795
2.786GlyLys: 2.786 ± 1.347
3.482GlyLeu: 3.482 ± 1.836
1.393GlyMet: 1.393 ± 0.674
2.786GlyAsn: 2.786 ± 1.469
3.482GlyPro: 3.482 ± 0.98
0.696GlyGln: 0.696 ± 0.367
5.571GlyArg: 5.571 ± 0.122
2.786GlySer: 2.786 ± 0.061
4.178GlyThr: 4.178 ± 2.021
11.142GlyVal: 11.142 ± 3.98
2.089GlyTrp: 2.089 ± 0.306
2.089GlyTyr: 2.089 ± 1.714
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.696HisAsp: 0.696 ± 0.367
2.786HisGlu: 2.786 ± 1.347
2.089HisPhe: 2.089 ± 0.306
1.393HisGly: 1.393 ± 0.674
0.696HisHis: 0.696 ± 0.367
0.696HisIle: 0.696 ± 0.367
2.089HisLys: 2.089 ± 0.306
2.786HisLeu: 2.786 ± 0.061
0.0HisMet: 0.0 ± 0.0
0.696HisAsn: 0.696 ± 0.367
2.786HisPro: 2.786 ± 1.347
2.089HisGln: 2.089 ± 0.306
2.786HisArg: 2.786 ± 0.061
0.696HisSer: 0.696 ± 0.367
0.0HisThr: 0.0 ± 0.0
3.482HisVal: 3.482 ± 0.98
0.0HisTrp: 0.0 ± 0.0
0.696HisTyr: 0.696 ± 0.367
0.0HisXaa: 0.0 ± 0.0
Ile
11.838IleAla: 11.838 ± 2.205
0.696IleCys: 0.696 ± 0.367
4.875IleAsp: 4.875 ± 1.162
4.875IleGlu: 4.875 ± 1.653
2.089IlePhe: 2.089 ± 0.306
5.571IleGly: 5.571 ± 1.286
1.393IleHis: 1.393 ± 0.734
3.482IleIle: 3.482 ± 1.836
3.482IleLys: 3.482 ± 1.836
1.393IleLeu: 1.393 ± 0.734
2.089IleMet: 2.089 ± 1.101
3.482IleAsn: 3.482 ± 0.98
3.482IlePro: 3.482 ± 0.428
2.786IleGln: 2.786 ± 1.347
3.482IleArg: 3.482 ± 1.836
1.393IleSer: 1.393 ± 0.734
1.393IleThr: 1.393 ± 0.734
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.786LysAla: 2.786 ± 0.061
0.696LysCys: 0.696 ± 0.367
2.786LysAsp: 2.786 ± 0.061
6.267LysGlu: 6.267 ± 0.919
2.089LysPhe: 2.089 ± 1.101
5.571LysGly: 5.571 ± 1.529
1.393LysHis: 1.393 ± 0.734
4.178LysIle: 4.178 ± 0.613
2.786LysLys: 2.786 ± 0.061
5.571LysLeu: 5.571 ± 0.122
1.393LysMet: 1.393 ± 0.674
2.089LysAsn: 2.089 ± 0.306
0.0LysPro: 0.0 ± 0.0
1.393LysGln: 1.393 ± 0.674
4.875LysArg: 4.875 ± 0.246
1.393LysSer: 1.393 ± 0.674
2.089LysThr: 2.089 ± 0.306
2.089LysVal: 2.089 ± 1.101
2.786LysTrp: 2.786 ± 0.061
1.393LysTyr: 1.393 ± 0.734
0.0LysXaa: 0.0 ± 0.0
Leu
3.482LeuAla: 3.482 ± 0.98
0.696LeuCys: 0.696 ± 0.367
6.267LeuAsp: 6.267 ± 1.897
5.571LeuGlu: 5.571 ± 1.529
4.178LeuPhe: 4.178 ± 0.795
2.089LeuGly: 2.089 ± 0.306
0.696LeuHis: 0.696 ± 0.367
4.875LeuIle: 4.875 ± 0.246
2.089LeuLys: 2.089 ± 1.101
11.838LeuLeu: 11.838 ± 0.798
0.696LeuMet: 0.696 ± 0.367
7.66LeuAsn: 7.66 ± 0.185
4.178LeuPro: 4.178 ± 0.795
4.178LeuGln: 4.178 ± 2.021
11.142LeuArg: 11.142 ± 1.165
9.053LeuSer: 9.053 ± 3.365
3.482LeuThr: 3.482 ± 0.98
0.696LeuVal: 0.696 ± 0.367
1.393LeuTrp: 1.393 ± 0.734
2.786LeuTyr: 2.786 ± 1.469
0.0LeuXaa: 0.0 ± 0.0
Met
0.696MetAla: 0.696 ± 0.367
0.0MetCys: 0.0 ± 0.0
2.089MetAsp: 2.089 ± 1.101
1.393MetGlu: 1.393 ± 0.734
0.0MetPhe: 0.0 ± 0.0
2.786MetGly: 2.786 ± 1.347
0.0MetHis: 0.0 ± 0.0
2.786MetIle: 2.786 ± 0.061
2.089MetLys: 2.089 ± 0.306
2.089MetLeu: 2.089 ± 1.101
1.393MetMet: 1.393 ± 0.734
2.089MetAsn: 2.089 ± 0.306
0.696MetPro: 0.696 ± 0.367
0.696MetGln: 0.696 ± 0.367
2.786MetArg: 2.786 ± 0.061
2.786MetSer: 2.786 ± 1.347
0.0MetThr: 0.0 ± 0.0
2.089MetVal: 2.089 ± 1.101
0.0MetTrp: 0.0 ± 0.0
1.393MetTyr: 1.393 ± 0.734
0.0MetXaa: 0.0 ± 0.0
Asn
2.089AsnAla: 2.089 ± 1.101
0.0AsnCys: 0.0 ± 0.0
3.482AsnAsp: 3.482 ± 0.428
1.393AsnGlu: 1.393 ± 0.734
1.393AsnPhe: 1.393 ± 0.674
0.696AsnGly: 0.696 ± 0.367
0.696AsnHis: 0.696 ± 0.367
2.786AsnIle: 2.786 ± 0.061
1.393AsnLys: 1.393 ± 0.674
7.66AsnLeu: 7.66 ± 1.593
0.696AsnMet: 0.696 ± 0.593
0.0AsnAsn: 0.0 ± 0.0
2.089AsnPro: 2.089 ± 0.306
2.786AsnGln: 2.786 ± 0.061
2.089AsnArg: 2.089 ± 1.101
2.089AsnSer: 2.089 ± 1.101
0.0AsnThr: 0.0 ± 0.0
0.696AsnVal: 0.696 ± 0.367
2.786AsnTrp: 2.786 ± 0.061
1.393AsnTyr: 1.393 ± 0.734
0.0AsnXaa: 0.0 ± 0.0
Pro
4.178ProAla: 4.178 ± 0.613
0.696ProCys: 0.696 ± 0.367
1.393ProAsp: 1.393 ± 2.081
2.089ProGlu: 2.089 ± 0.306
2.089ProPhe: 2.089 ± 1.101
5.571ProGly: 5.571 ± 1.286
0.0ProHis: 0.0 ± 0.0
1.393ProIle: 1.393 ± 0.734
1.393ProLys: 1.393 ± 0.734
6.267ProLeu: 6.267 ± 2.327
2.089ProMet: 2.089 ± 1.101
0.0ProAsn: 0.0 ± 0.0
2.089ProPro: 2.089 ± 0.306
1.393ProGln: 1.393 ± 0.734
2.786ProArg: 2.786 ± 0.061
4.875ProSer: 4.875 ± 2.57
2.089ProThr: 2.089 ± 0.306
4.178ProVal: 4.178 ± 0.613
0.0ProTrp: 0.0 ± 0.0
0.696ProTyr: 0.696 ± 0.367
0.0ProXaa: 0.0 ± 0.0
Gln
2.089GlnAla: 2.089 ± 0.306
0.696GlnCys: 0.696 ± 0.367
0.696GlnAsp: 0.696 ± 1.041
4.178GlnGlu: 4.178 ± 0.613
3.482GlnPhe: 3.482 ± 0.98
0.696GlnGly: 0.696 ± 1.041
1.393GlnHis: 1.393 ± 0.674
2.089GlnIle: 2.089 ± 1.101
2.786GlnLys: 2.786 ± 1.347
1.393GlnLeu: 1.393 ± 0.674
1.393GlnMet: 1.393 ± 0.674
0.0GlnAsn: 0.0 ± 0.0
0.696GlnPro: 0.696 ± 0.367
1.393GlnGln: 1.393 ± 0.674
3.482GlnArg: 3.482 ± 2.388
0.0GlnSer: 0.0 ± 0.0
2.089GlnThr: 2.089 ± 1.101
3.482GlnVal: 3.482 ± 2.388
0.696GlnTrp: 0.696 ± 0.367
1.393GlnTyr: 1.393 ± 0.674
0.0GlnXaa: 0.0 ± 0.0
Arg
10.446ArgAla: 10.446 ± 1.532
2.786ArgCys: 2.786 ± 0.061
3.482ArgAsp: 3.482 ± 0.428
4.875ArgGlu: 4.875 ± 0.246
1.393ArgPhe: 1.393 ± 0.734
6.964ArgGly: 6.964 ± 0.552
4.178ArgHis: 4.178 ± 0.613
1.393ArgIle: 1.393 ± 0.734
2.786ArgLys: 2.786 ± 0.061
4.875ArgLeu: 4.875 ± 1.162
1.393ArgMet: 1.393 ± 0.274
2.089ArgAsn: 2.089 ± 0.306
6.267ArgPro: 6.267 ± 1.897
4.875ArgGln: 4.875 ± 3.061
4.875ArgArg: 4.875 ± 0.246
2.786ArgSer: 2.786 ± 1.469
2.786ArgThr: 2.786 ± 0.061
9.053ArgVal: 9.053 ± 0.55
1.393ArgTrp: 1.393 ± 0.734
2.786ArgTyr: 2.786 ± 1.469
0.0ArgXaa: 0.0 ± 0.0
Ser
6.267SerAla: 6.267 ± 0.489
2.089SerCys: 2.089 ± 1.101
2.089SerAsp: 2.089 ± 1.101
1.393SerGlu: 1.393 ± 0.734
2.089SerPhe: 2.089 ± 1.101
6.964SerGly: 6.964 ± 1.96
0.696SerHis: 0.696 ± 0.367
1.393SerIle: 1.393 ± 0.734
4.875SerLys: 4.875 ± 2.57
4.178SerLeu: 4.178 ± 0.795
0.696SerMet: 0.696 ± 0.367
2.089SerAsn: 2.089 ± 1.101
3.482SerPro: 3.482 ± 0.428
1.393SerGln: 1.393 ± 0.674
4.875SerArg: 4.875 ± 0.246
6.964SerSer: 6.964 ± 2.264
1.393SerThr: 1.393 ± 0.674
4.875SerVal: 4.875 ± 1.162
0.0SerTrp: 0.0 ± 0.0
0.696SerTyr: 0.696 ± 0.367
0.0SerXaa: 0.0 ± 0.0
Thr
2.786ThrAla: 2.786 ± 0.061
0.0ThrCys: 0.0 ± 0.0
2.089ThrAsp: 2.089 ± 0.306
0.0ThrGlu: 0.0 ± 0.0
2.089ThrPhe: 2.089 ± 1.714
4.178ThrGly: 4.178 ± 0.795
0.0ThrHis: 0.0 ± 0.0
0.696ThrIle: 0.696 ± 0.367
2.786ThrLys: 2.786 ± 0.061
2.089ThrLeu: 2.089 ± 1.101
1.393ThrMet: 1.393 ± 0.674
0.696ThrAsn: 0.696 ± 1.041
2.089ThrPro: 2.089 ± 0.306
0.696ThrGln: 0.696 ± 1.041
3.482ThrArg: 3.482 ± 0.428
5.571ThrSer: 5.571 ± 0.122
1.393ThrThr: 1.393 ± 0.734
2.786ThrVal: 2.786 ± 1.347
0.0ThrTrp: 0.0 ± 0.0
2.089ThrTyr: 2.089 ± 0.306
0.0ThrXaa: 0.0 ± 0.0
Val
4.178ValAla: 4.178 ± 2.021
0.696ValCys: 0.696 ± 0.367
3.482ValAsp: 3.482 ± 0.98
5.571ValGlu: 5.571 ± 1.286
1.393ValPhe: 1.393 ± 0.734
5.571ValGly: 5.571 ± 1.286
3.482ValHis: 3.482 ± 0.98
2.089ValIle: 2.089 ± 1.101
4.875ValLys: 4.875 ± 1.162
3.482ValLeu: 3.482 ± 1.836
4.178ValMet: 4.178 ± 0.795
0.696ValAsn: 0.696 ± 0.367
6.964ValPro: 6.964 ± 0.552
2.786ValGln: 2.786 ± 1.347
7.66ValArg: 7.66 ± 0.185
2.786ValSer: 2.786 ± 1.347
4.875ValThr: 4.875 ± 1.653
2.089ValVal: 2.089 ± 1.101
0.696ValTrp: 0.696 ± 0.367
2.089ValTyr: 2.089 ± 0.306
0.0ValXaa: 0.0 ± 0.0
Trp
1.393TrpAla: 1.393 ± 0.674
0.0TrpCys: 0.0 ± 0.0
1.393TrpAsp: 1.393 ± 0.734
1.393TrpGlu: 1.393 ± 0.734
0.696TrpPhe: 0.696 ± 0.367
0.696TrpGly: 0.696 ± 0.367
0.0TrpHis: 0.0 ± 0.0
3.482TrpIle: 3.482 ± 0.98
0.696TrpLys: 0.696 ± 0.367
1.393TrpLeu: 1.393 ± 0.734
1.393TrpMet: 1.393 ± 0.734
2.786TrpAsn: 2.786 ± 1.347
0.0TrpPro: 0.0 ± 0.0
0.696TrpGln: 0.696 ± 0.367
1.393TrpArg: 1.393 ± 0.734
0.696TrpSer: 0.696 ± 0.367
0.696TrpThr: 0.696 ± 0.367
0.696TrpVal: 0.696 ± 0.367
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.696TyrAla: 0.696 ± 0.367
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.089TyrGlu: 2.089 ± 0.306
0.0TyrPhe: 0.0 ± 0.0
2.089TyrGly: 2.089 ± 1.101
1.393TyrHis: 1.393 ± 0.734
3.482TyrIle: 3.482 ± 0.428
1.393TyrLys: 1.393 ± 0.734
4.178TyrLeu: 4.178 ± 0.795
1.393TyrMet: 1.393 ± 0.674
1.393TyrAsn: 1.393 ± 0.734
0.0TyrPro: 0.0 ± 0.0
0.696TyrGln: 0.696 ± 0.367
2.786TyrArg: 2.786 ± 1.469
2.786TyrSer: 2.786 ± 0.061
2.089TyrThr: 2.089 ± 0.306
2.089TyrVal: 2.089 ± 0.306
1.393TyrTrp: 1.393 ± 0.734
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1437 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski