Amino acid dipepetide frequency for Ohtaekwangia koreensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.63AlaAla: 5.63 ± 0.071	0.668AlaCys: 0.668 ± 0.02	3.871AlaAsp: 3.871 ± 0.04	4.133AlaGlu: 4.133 ± 0.053	3.368AlaPhe: 3.368 ± 0.043	5.433AlaGly: 5.433 ± 0.073	1.215AlaHis: 1.215 ± 0.026	5.451AlaIle: 5.451 ± 0.051	4.183AlaLys: 4.183 ± 0.051	6.905AlaLeu: 6.905 ± 0.069	1.679AlaMet: 1.679 ± 0.029	3.392AlaAsn: 3.392 ± 0.052	2.228AlaPro: 2.228 ± 0.037	2.769AlaGln: 2.769 ± 0.038	2.748AlaArg: 2.748 ± 0.041	5.224AlaSer: 5.224 ± 0.06	4.381AlaThr: 4.381 ± 0.075	4.554AlaVal: 4.554 ± 0.052	0.913AlaTrp: 0.913 ± 0.022	2.665AlaTyr: 2.665 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.516CysAla: 0.516 ± 0.02	0.117CysCys: 0.117 ± 0.008	0.39CysAsp: 0.39 ± 0.016	0.423CysGlu: 0.423 ± 0.017	0.379CysPhe: 0.379 ± 0.013	0.56CysGly: 0.56 ± 0.018	0.167CysHis: 0.167 ± 0.01	0.607CysIle: 0.607 ± 0.017	0.434CysLys: 0.434 ± 0.015	0.694CysLeu: 0.694 ± 0.017	0.18CysMet: 0.18 ± 0.009	0.368CysAsn: 0.368 ± 0.015	0.309CysPro: 0.309 ± 0.015	0.214CysGln: 0.214 ± 0.01	0.286CysArg: 0.286 ± 0.012	0.6CysSer: 0.6 ± 0.019	0.441CysThr: 0.441 ± 0.017	0.463CysVal: 0.463 ± 0.015	0.094CysTrp: 0.094 ± 0.007	0.312CysTyr: 0.312 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.984AspAla: 3.984 ± 0.052	0.354AspCys: 0.354 ± 0.013	2.812AspAsp: 2.812 ± 0.037	3.406AspGlu: 3.406 ± 0.043	3.079AspPhe: 3.079 ± 0.038	3.922AspGly: 3.922 ± 0.061	1.1AspHis: 1.1 ± 0.025	4.123AspIle: 4.123 ± 0.048	3.778AspLys: 3.778 ± 0.046	4.992AspLeu: 4.992 ± 0.051	1.025AspMet: 1.025 ± 0.025	2.646AspAsn: 2.646 ± 0.036	2.28AspPro: 2.28 ± 0.033	1.923AspGln: 1.923 ± 0.03	2.292AspArg: 2.292 ± 0.038	3.155AspSer: 3.155 ± 0.045	2.578AspThr: 2.578 ± 0.036	3.612AspVal: 3.612 ± 0.044	0.735AspTrp: 0.735 ± 0.021	2.478AspTyr: 2.478 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	4.315GluAla: 4.315 ± 0.065	0.34GluCys: 0.34 ± 0.013	3.114GluAsp: 3.114 ± 0.044	4.214GluGlu: 4.214 ± 0.059	2.675GluPhe: 2.675 ± 0.035	3.689GluGly: 3.689 ± 0.047	1.135GluHis: 1.135 ± 0.024	4.387GluIle: 4.387 ± 0.049	5.004GluLys: 5.004 ± 0.069	5.631GluLeu: 5.631 ± 0.066	1.387GluMet: 1.387 ± 0.024	3.23GluAsn: 3.23 ± 0.039	1.701GluPro: 1.701 ± 0.028	2.378GluGln: 2.378 ± 0.041	2.759GluArg: 2.759 ± 0.042	3.393GluSer: 3.393 ± 0.045	3.105GluThr: 3.105 ± 0.041	4.128GluVal: 4.128 ± 0.049	0.723GluTrp: 0.723 ± 0.018	2.375GluTyr: 2.375 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.1PheAla: 3.1 ± 0.042	0.443PheCys: 0.443 ± 0.013	2.972PheAsp: 2.972 ± 0.036	2.853PheGlu: 2.853 ± 0.038	2.535PhePhe: 2.535 ± 0.044	3.103PheGly: 3.103 ± 0.046	0.922PheHis: 0.922 ± 0.023	3.65PheIle: 3.65 ± 0.049	3.037PheLys: 3.037 ± 0.043	4.346PheLeu: 4.346 ± 0.054	1.049PheMet: 1.049 ± 0.02	2.769PheAsn: 2.769 ± 0.039	1.671PhePro: 1.671 ± 0.027	1.679PheGln: 1.679 ± 0.028	2.028PheArg: 2.028 ± 0.03	3.736PheSer: 3.736 ± 0.04	3.358PheThr: 3.358 ± 0.044	2.964PheVal: 2.964 ± 0.039	0.6PheTrp: 0.6 ± 0.017	2.039PheTyr: 2.039 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	4.466GlyAla: 4.466 ± 0.056	0.596GlyCys: 0.596 ± 0.022	3.392GlyAsp: 3.392 ± 0.045	3.526GlyGlu: 3.526 ± 0.039	3.399GlyPhe: 3.399 ± 0.041	4.74GlyGly: 4.74 ± 0.077	1.11GlyHis: 1.11 ± 0.026	5.414GlyIle: 5.414 ± 0.057	5.145GlyLys: 5.145 ± 0.058	5.91GlyLeu: 5.91 ± 0.066	1.544GlyMet: 1.544 ± 0.03	3.698GlyAsn: 3.698 ± 0.056	1.619GlyPro: 1.619 ± 0.034	2.125GlyGln: 2.125 ± 0.032	2.526GlyArg: 2.526 ± 0.044	4.624GlySer: 4.624 ± 0.065	4.704GlyThr: 4.704 ± 0.098	4.464GlyVal: 4.464 ± 0.05	0.98GlyTrp: 0.98 ± 0.026	2.997GlyTyr: 2.997 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	1.379HisAla: 1.379 ± 0.024	0.171HisCys: 0.171 ± 0.009	1.05HisAsp: 1.05 ± 0.022	1.204HisGlu: 1.204 ± 0.023	1.069HisPhe: 1.069 ± 0.022	1.22HisGly: 1.22 ± 0.027	0.571HisHis: 0.571 ± 0.017	1.262HisIle: 1.262 ± 0.026	0.957HisLys: 0.957 ± 0.021	1.755HisLeu: 1.755 ± 0.032	0.37HisMet: 0.37 ± 0.014	0.845HisAsn: 0.845 ± 0.02	0.959HisPro: 0.959 ± 0.024	0.759HisGln: 0.759 ± 0.02	0.859HisArg: 0.859 ± 0.018	1.074HisSer: 1.074 ± 0.024	1.081HisThr: 1.081 ± 0.022	1.163HisVal: 1.163 ± 0.026	0.293HisTrp: 0.293 ± 0.014	0.904HisTyr: 0.904 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.86IleAla: 5.86 ± 0.06	0.589IleCys: 0.589 ± 0.021	4.208IleAsp: 4.208 ± 0.04	4.408IleGlu: 4.408 ± 0.05	3.412IlePhe: 3.412 ± 0.042	4.953IleGly: 4.953 ± 0.052	1.522IleHis: 1.522 ± 0.026	4.87IleIle: 4.87 ± 0.056	4.432IleLys: 4.432 ± 0.042	6.752IleLeu: 6.752 ± 0.068	1.28IleMet: 1.28 ± 0.025	3.78IleAsn: 3.78 ± 0.042	3.258IlePro: 3.258 ± 0.041	2.609IleGln: 2.609 ± 0.038	3.209IleArg: 3.209 ± 0.035	5.072IleSer: 5.072 ± 0.048	4.876IleThr: 4.876 ± 0.055	4.78IleVal: 4.78 ± 0.057	0.711IleTrp: 0.711 ± 0.022	2.958IleTyr: 2.958 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	4.766LysAla: 4.766 ± 0.056	0.304LysCys: 0.304 ± 0.012	4.084LysAsp: 4.084 ± 0.056	4.91LysGlu: 4.91 ± 0.057	2.743LysPhe: 2.743 ± 0.036	4.153LysGly: 4.153 ± 0.048	1.221LysHis: 1.221 ± 0.028	4.921LysIle: 4.921 ± 0.051	5.357LysLys: 5.357 ± 0.073	5.976LysLeu: 5.976 ± 0.067	1.647LysMet: 1.647 ± 0.028	3.899LysAsn: 3.899 ± 0.051	2.465LysPro: 2.465 ± 0.039	2.463LysGln: 2.463 ± 0.035	2.933LysArg: 2.933 ± 0.039	4.079LysSer: 4.079 ± 0.05	3.878LysThr: 3.878 ± 0.049	4.483LysVal: 4.483 ± 0.046	0.665LysTrp: 0.665 ± 0.017	2.678LysTyr: 2.678 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	6.585LeuAla: 6.585 ± 0.069	0.737LeuCys: 0.737 ± 0.019	4.668LeuAsp: 4.668 ± 0.05	5.274LeuGlu: 5.274 ± 0.062	4.349LeuPhe: 4.349 ± 0.052	5.464LeuGly: 5.464 ± 0.057	1.801LeuHis: 1.801 ± 0.034	6.244LeuIle: 6.244 ± 0.067	6.834LeuLys: 6.834 ± 0.074	8.937LeuLeu: 8.937 ± 0.084	2.027LeuMet: 2.027 ± 0.033	4.938LeuAsn: 4.938 ± 0.053	3.899LeuPro: 3.899 ± 0.043	3.76LeuGln: 3.76 ± 0.051	4.098LeuArg: 4.098 ± 0.044	6.983LeuSer: 6.983 ± 0.071	5.747LeuThr: 5.747 ± 0.067	5.64LeuVal: 5.64 ± 0.062	1.021LeuTrp: 1.021 ± 0.024	3.547LeuTyr: 3.547 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	1.581MetAla: 1.581 ± 0.029	0.139MetCys: 0.139 ± 0.008	1.115MetAsp: 1.115 ± 0.025	1.303MetGlu: 1.303 ± 0.028	0.809MetPhe: 0.809 ± 0.02	1.338MetGly: 1.338 ± 0.028	0.436MetHis: 0.436 ± 0.015	1.553MetIle: 1.553 ± 0.029	2.025MetLys: 2.025 ± 0.033	2.087MetLeu: 2.087 ± 0.032	0.588MetMet: 0.588 ± 0.018	1.244MetAsn: 1.244 ± 0.025	0.917MetPro: 0.917 ± 0.02	0.869MetGln: 0.869 ± 0.021	1.066MetArg: 1.066 ± 0.022	1.314MetSer: 1.314 ± 0.026	1.092MetThr: 1.092 ± 0.026	1.346MetVal: 1.346 ± 0.027	0.197MetTrp: 0.197 ± 0.011	0.649MetTyr: 0.649 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.809AsnAla: 3.809 ± 0.045	0.367AsnCys: 0.367 ± 0.014	2.829AsnAsp: 2.829 ± 0.051	2.965AsnGlu: 2.965 ± 0.041	2.6AsnPhe: 2.6 ± 0.036	3.94AsnGly: 3.94 ± 0.067	0.98AsnHis: 0.98 ± 0.02	3.907AsnIle: 3.907 ± 0.048	3.176AsnLys: 3.176 ± 0.04	4.652AsnLeu: 4.652 ± 0.052	1.058AsnMet: 1.058 ± 0.021	2.919AsnAsn: 2.919 ± 0.052	2.566AsnPro: 2.566 ± 0.042	1.898AsnGln: 1.898 ± 0.032	2.235AsnArg: 2.235 ± 0.037	3.267AsnSer: 3.267 ± 0.045	3.324AsnThr: 3.324 ± 0.048	3.269AsnVal: 3.269 ± 0.044	0.643AsnTrp: 0.643 ± 0.017	2.351AsnTyr: 2.351 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.06ProAla: 3.06 ± 0.054	0.232ProCys: 0.232 ± 0.011	2.451ProAsp: 2.451 ± 0.031	2.766ProGlu: 2.766 ± 0.039	1.83ProPhe: 1.83 ± 0.032	2.737ProGly: 2.737 ± 0.039	0.678ProHis: 0.678 ± 0.017	2.356ProIle: 2.356 ± 0.034	1.912ProLys: 1.912 ± 0.039	3.32ProLeu: 3.32 ± 0.041	0.785ProMet: 0.785 ± 0.021	1.73ProAsn: 1.73 ± 0.032	1.115ProPro: 1.115 ± 0.029	1.282ProGln: 1.282 ± 0.026	1.186ProArg: 1.186 ± 0.028	2.583ProSer: 2.583 ± 0.038	1.959ProThr: 1.959 ± 0.036	3.282ProVal: 3.282 ± 0.043	0.472ProTrp: 0.472 ± 0.016	1.45ProTyr: 1.45 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	2.71GlnAla: 2.71 ± 0.036	0.215GlnCys: 0.215 ± 0.009	1.797GlnAsp: 1.797 ± 0.031	2.275GlnGlu: 2.275 ± 0.042	1.611GlnPhe: 1.611 ± 0.027	2.25GlnGly: 2.25 ± 0.032	0.806GlnHis: 0.806 ± 0.021	2.236GlnIle: 2.236 ± 0.034	2.56GlnLys: 2.56 ± 0.044	3.441GlnLeu: 3.441 ± 0.047	0.824GlnMet: 0.824 ± 0.021	1.924GlnAsn: 1.924 ± 0.035	1.376GlnPro: 1.376 ± 0.03	2.008GlnGln: 2.008 ± 0.038	1.794GlnArg: 1.794 ± 0.034	2.434GlnSer: 2.434 ± 0.034	2.042GlnThr: 2.042 ± 0.032	2.351GlnVal: 2.351 ± 0.038	0.575GlnTrp: 0.575 ± 0.018	1.625GlnTyr: 1.625 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.598ArgAla: 2.598 ± 0.04	0.249ArgCys: 0.249 ± 0.012	2.207ArgAsp: 2.207 ± 0.033	2.701ArgGlu: 2.701 ± 0.041	2.123ArgPhe: 2.123 ± 0.032	2.309ArgGly: 2.309 ± 0.039	0.758ArgHis: 0.758 ± 0.019	3.36ArgIle: 3.36 ± 0.042	3.301ArgLys: 3.301 ± 0.045	3.901ArgLeu: 3.901 ± 0.047	1.115ArgMet: 1.115 ± 0.022	2.353ArgAsn: 2.353 ± 0.034	1.379ArgPro: 1.379 ± 0.027	1.542ArgGln: 1.542 ± 0.028	1.54ArgArg: 1.54 ± 0.03	2.593ArgSer: 2.593 ± 0.039	2.308ArgThr: 2.308 ± 0.034	2.73ArgVal: 2.73 ± 0.034	0.615ArgTrp: 0.615 ± 0.017	2.003ArgTyr: 2.003 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	4.626SerAla: 4.626 ± 0.057	0.57SerCys: 0.57 ± 0.017	3.538SerAsp: 3.538 ± 0.045	3.597SerGlu: 3.597 ± 0.044	3.71SerPhe: 3.71 ± 0.046	5.205SerGly: 5.205 ± 0.073	1.219SerHis: 1.219 ± 0.025	5.42SerIle: 5.42 ± 0.055	4.076SerLys: 4.076 ± 0.044	6.574SerLeu: 6.574 ± 0.067	1.422SerMet: 1.422 ± 0.03	3.382SerAsn: 3.382 ± 0.054	2.462SerPro: 2.462 ± 0.043	2.258SerGln: 2.258 ± 0.034	2.686SerArg: 2.686 ± 0.037	4.829SerSer: 4.829 ± 0.057	4.029SerThr: 4.029 ± 0.058	4.583SerVal: 4.583 ± 0.054	0.841SerTrp: 0.841 ± 0.021	2.811SerTyr: 2.811 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	4.553ThrAla: 4.553 ± 0.058	0.442ThrCys: 0.442 ± 0.017	3.397ThrAsp: 3.397 ± 0.042	3.264ThrGlu: 3.264 ± 0.042	3.18ThrPhe: 3.18 ± 0.05	4.822ThrGly: 4.822 ± 0.08	1.024ThrHis: 1.024 ± 0.022	4.795ThrIle: 4.795 ± 0.063	3.261ThrLys: 3.261 ± 0.042	5.982ThrLeu: 5.982 ± 0.061	1.059ThrMet: 1.059 ± 0.024	2.957ThrAsn: 2.957 ± 0.047	2.636ThrPro: 2.636 ± 0.044	2.015ThrGln: 2.015 ± 0.035	2.211ThrArg: 2.211 ± 0.034	4.253ThrSer: 4.253 ± 0.07	4.062ThrThr: 4.062 ± 0.068	4.244ThrVal: 4.244 ± 0.066	0.806ThrTrp: 0.806 ± 0.024	2.382ThrTyr: 2.382 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	4.499ValAla: 4.499 ± 0.05	0.577ValCys: 0.577 ± 0.019	3.432ValAsp: 3.432 ± 0.041	3.635ValGlu: 3.635 ± 0.043	3.033ValPhe: 3.033 ± 0.042	3.783ValGly: 3.783 ± 0.046	1.17ValHis: 1.17 ± 0.02	4.888ValIle: 4.888 ± 0.053	4.588ValLys: 4.588 ± 0.054	6.042ValLeu: 6.042 ± 0.051	1.539ValMet: 1.539 ± 0.029	3.614ValAsn: 3.614 ± 0.05	2.349ValPro: 2.349 ± 0.034	2.187ValGln: 2.187 ± 0.035	2.688ValArg: 2.688 ± 0.035	4.742ValSer: 4.742 ± 0.055	4.487ValThr: 4.487 ± 0.071	4.607ValVal: 4.607 ± 0.056	0.774ValTrp: 0.774 ± 0.02	2.736ValTyr: 2.736 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.756TrpAla: 0.756 ± 0.023	0.111TrpCys: 0.111 ± 0.008	0.64TrpAsp: 0.64 ± 0.018	0.676TrpGlu: 0.676 ± 0.018	0.603TrpPhe: 0.603 ± 0.017	0.791TrpGly: 0.791 ± 0.022	0.252TrpHis: 0.252 ± 0.013	0.913TrpIle: 0.913 ± 0.024	0.942TrpLys: 0.942 ± 0.025	1.13TrpLeu: 1.13 ± 0.026	0.332TrpMet: 0.332 ± 0.012	0.769TrpAsn: 0.769 ± 0.021	0.356TrpPro: 0.356 ± 0.014	0.503TrpGln: 0.503 ± 0.017	0.54TrpArg: 0.54 ± 0.016	0.885TrpSer: 0.885 ± 0.026	0.762TrpThr: 0.762 ± 0.02	0.735TrpVal: 0.735 ± 0.019	0.229TrpTrp: 0.229 ± 0.012	0.514TrpTyr: 0.514 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.617TyrAla: 2.617 ± 0.037	0.333TyrCys: 0.333 ± 0.013	2.308TyrAsp: 2.308 ± 0.037	2.153TyrGlu: 2.153 ± 0.034	2.346TyrPhe: 2.346 ± 0.036	2.564TyrGly: 2.564 ± 0.046	0.855TyrHis: 0.855 ± 0.019	3.184TyrIle: 3.184 ± 0.04	2.624TyrLys: 2.624 ± 0.036	3.528TyrLeu: 3.528 ± 0.044	0.759TyrMet: 0.759 ± 0.017	2.297TyrAsn: 2.297 ± 0.041	1.642TyrPro: 1.642 ± 0.031	1.611TyrGln: 1.611 ± 0.028	2.004TyrArg: 2.004 ± 0.031	2.997TyrSer: 2.997 ± 0.044	3.13TyrThr: 3.13 ± 0.043	1.972TyrVal: 1.972 ± 0.034	0.55TyrTrp: 0.55 ± 0.018	1.959TyrTyr: 1.959 ± 0.035	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 5828 proteins (2158248 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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