Amino acid dipepetide frequency for Hosta virus X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.99AlaAla: 6.99 ± 4.158
0.466AlaCys: 0.466 ± 0.701
2.796AlaAsp: 2.796 ± 0.944
3.262AlaGlu: 3.262 ± 1.093
2.33AlaPhe: 2.33 ± 2.556
5.592AlaGly: 5.592 ± 2.213
3.262AlaHis: 3.262 ± 0.636
2.796AlaIle: 2.796 ± 2.666
5.126AlaLys: 5.126 ± 1.939
6.99AlaLeu: 6.99 ± 3.603
2.33AlaMet: 2.33 ± 0.85
6.058AlaAsn: 6.058 ± 1.219
6.99AlaPro: 6.99 ± 4.094
2.796AlaGln: 2.796 ± 0.944
4.66AlaArg: 4.66 ± 0.868
5.126AlaSer: 5.126 ± 1.448
4.66AlaThr: 4.66 ± 1.592
4.194AlaVal: 4.194 ± 3.267
0.932AlaTrp: 0.932 ± 0.487
3.262AlaTyr: 3.262 ± 1.108
0.0AlaXaa: 0.0 ± 0.0
Cys
1.398CysAla: 1.398 ± 2.402
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.466CysGlu: 0.466 ± 0.244
0.0CysPhe: 0.0 ± 0.0
0.466CysGly: 0.466 ± 0.244
0.466CysHis: 0.466 ± 1.224
0.0CysIle: 0.0 ± 0.0
0.932CysLys: 0.932 ± 1.989
0.466CysLeu: 0.466 ± 1.282
0.466CysMet: 0.466 ± 0.701
0.466CysAsn: 0.466 ± 0.244
3.728CysPro: 3.728 ± 3.423
0.932CysGln: 0.932 ± 0.487
1.864CysArg: 1.864 ± 1.063
1.864CysSer: 1.864 ± 1.71
0.0CysThr: 0.0 ± 0.0
0.932CysVal: 0.932 ± 0.487
0.0CysTrp: 0.0 ± 0.0
0.466CysTyr: 0.466 ± 0.701
0.0CysXaa: 0.0 ± 0.0
Asp
2.796AspAla: 2.796 ± 1.037
0.466AspCys: 0.466 ± 0.995
1.398AspAsp: 1.398 ± 0.771
3.262AspGlu: 3.262 ± 1.509
4.66AspPhe: 4.66 ± 1.229
3.728AspGly: 3.728 ± 1.74
0.466AspHis: 0.466 ± 0.244
3.262AspIle: 3.262 ± 2.461
1.864AspLys: 1.864 ± 0.758
6.524AspLeu: 6.524 ± 2.628
0.466AspMet: 0.466 ± 0.244
0.932AspAsn: 0.932 ± 1.121
3.728AspPro: 3.728 ± 1.297
0.932AspGln: 0.932 ± 0.487
1.398AspArg: 1.398 ± 0.731
2.33AspSer: 2.33 ± 1.192
1.398AspThr: 1.398 ± 0.608
2.33AspVal: 2.33 ± 0.67
0.466AspTrp: 0.466 ± 0.244
0.932AspTyr: 0.932 ± 0.487
0.0AspXaa: 0.0 ± 0.0
Glu
4.194GluAla: 4.194 ± 2.193
0.466GluCys: 0.466 ± 0.244
2.796GluAsp: 2.796 ± 0.944
4.194GluGlu: 4.194 ± 1.535
2.33GluPhe: 2.33 ± 0.67
2.796GluGly: 2.796 ± 1.445
0.466GluHis: 0.466 ± 0.701
4.194GluIle: 4.194 ± 1.56
6.524GluLys: 6.524 ± 3.411
6.058GluLeu: 6.058 ± 2.279
0.932GluMet: 0.932 ± 0.487
2.796GluAsn: 2.796 ± 1.037
4.194GluPro: 4.194 ± 2.193
3.728GluGln: 3.728 ± 0.739
2.33GluArg: 2.33 ± 2.691
1.398GluSer: 1.398 ± 0.771
4.194GluThr: 4.194 ± 2.193
1.864GluVal: 1.864 ± 0.941
0.0GluTrp: 0.0 ± 0.0
0.466GluTyr: 0.466 ± 0.995
0.0GluXaa: 0.0 ± 0.0
Phe
4.66PheAla: 4.66 ± 1.716
1.864PheCys: 1.864 ± 0.941
4.194PheAsp: 4.194 ± 1.823
2.33PheGlu: 2.33 ± 0.82
1.398PhePhe: 1.398 ± 0.731
0.466PheGly: 0.466 ± 0.244
2.33PheHis: 2.33 ± 1.218
2.796PheIle: 2.796 ± 0.944
1.864PheLys: 1.864 ± 0.758
7.456PheLeu: 7.456 ± 1.191
0.466PheMet: 0.466 ± 0.244
1.398PheAsn: 1.398 ± 1.065
1.398PhePro: 1.398 ± 1.009
2.33PheGln: 2.33 ± 1.116
1.398PheArg: 1.398 ± 0.731
3.262PheSer: 3.262 ± 2.461
2.796PheThr: 2.796 ± 1.14
1.864PheVal: 1.864 ± 0.975
1.398PheTrp: 1.398 ± 0.731
0.932PheTyr: 0.932 ± 0.487
0.0PheXaa: 0.0 ± 0.0
Gly
4.66GlyAla: 4.66 ± 2.495
0.466GlyCys: 0.466 ± 0.244
4.194GlyAsp: 4.194 ± 1.701
1.864GlyGlu: 1.864 ± 0.758
1.864GlyPhe: 1.864 ± 0.975
2.33GlyGly: 2.33 ± 1.136
2.796GlyHis: 2.796 ± 1.037
3.262GlyIle: 3.262 ± 1.406
3.262GlyLys: 3.262 ± 1.108
3.262GlyLeu: 3.262 ± 1.503
0.466GlyMet: 0.466 ± 1.14
3.262GlyAsn: 3.262 ± 2.528
4.194GlyPro: 4.194 ± 1.007
1.864GlyGln: 1.864 ± 0.758
0.932GlyArg: 0.932 ± 0.609
3.262GlySer: 3.262 ± 2.664
5.126GlyThr: 5.126 ± 0.994
1.398GlyVal: 1.398 ± 1.333
0.466GlyTrp: 0.466 ± 0.244
0.932GlyTyr: 0.932 ± 0.609
0.0GlyXaa: 0.0 ± 0.0
His
3.728HisAla: 3.728 ± 0.957
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.932HisGlu: 0.932 ± 0.487
1.398HisPhe: 1.398 ± 0.731
1.864HisGly: 1.864 ± 1.194
0.466HisHis: 0.466 ± 0.244
2.33HisIle: 2.33 ± 1.192
1.864HisLys: 1.864 ± 0.697
3.728HisLeu: 3.728 ± 1.239
0.466HisMet: 0.466 ± 0.244
0.932HisAsn: 0.932 ± 0.487
0.932HisPro: 0.932 ± 0.856
2.796HisGln: 2.796 ± 1.037
2.796HisArg: 2.796 ± 1.75
2.796HisSer: 2.796 ± 4.004
3.262HisThr: 3.262 ± 0.907
0.932HisVal: 0.932 ± 2.447
0.932HisTrp: 0.932 ± 0.487
1.398HisTyr: 1.398 ± 1.84
0.0HisXaa: 0.0 ± 0.0
Ile
2.796IleAla: 2.796 ± 0.606
0.932IleCys: 0.932 ± 0.856
0.466IleAsp: 0.466 ± 0.244
2.796IleGlu: 2.796 ± 1.037
2.796IlePhe: 2.796 ± 0.606
2.33IleGly: 2.33 ± 2.292
1.864IleHis: 1.864 ± 3.113
3.728IleIle: 3.728 ± 0.95
4.194IleLys: 4.194 ± 2.193
4.194IleLeu: 4.194 ± 0.915
0.932IleMet: 0.932 ± 0.487
2.33IleAsn: 2.33 ± 1.218
3.728IlePro: 3.728 ± 0.95
2.796IleGln: 2.796 ± 1.462
3.728IleArg: 3.728 ± 0.749
3.262IleSer: 3.262 ± 2.664
4.66IleThr: 4.66 ± 1.109
0.466IleVal: 0.466 ± 0.244
0.932IleTrp: 0.932 ± 1.483
3.262IleTyr: 3.262 ± 1.406
0.0IleXaa: 0.0 ± 0.0
Lys
2.796LysAla: 2.796 ± 1.462
1.398LysCys: 1.398 ± 0.771
5.126LysAsp: 5.126 ± 1.296
4.194LysGlu: 4.194 ± 1.689
2.33LysPhe: 2.33 ± 1.218
2.33LysGly: 2.33 ± 1.218
2.796LysHis: 2.796 ± 0.944
2.33LysIle: 2.33 ± 0.85
2.33LysLys: 2.33 ± 1.218
6.524LysLeu: 6.524 ± 2.216
0.466LysMet: 0.466 ± 0.244
1.864LysAsn: 1.864 ± 0.975
4.66LysPro: 4.66 ± 1.717
2.33LysGln: 2.33 ± 1.218
3.262LysArg: 3.262 ± 1.108
4.66LysSer: 4.66 ± 1.468
6.058LysThr: 6.058 ± 2.044
2.33LysVal: 2.33 ± 1.218
2.33LysTrp: 2.33 ± 0.85
1.864LysTyr: 1.864 ± 0.697
0.0LysXaa: 0.0 ± 0.0
Leu
6.99LeuAla: 6.99 ± 4.133
1.864LeuCys: 1.864 ± 1.882
2.33LeuAsp: 2.33 ± 2.691
4.194LeuGlu: 4.194 ± 1.618
4.66LeuPhe: 4.66 ± 2.437
6.058LeuGly: 6.058 ± 2.261
2.33LeuHis: 2.33 ± 0.85
4.66LeuIle: 4.66 ± 1.373
7.922LeuLys: 7.922 ± 4.143
7.922LeuLeu: 7.922 ± 4.593
0.932LeuMet: 0.932 ± 0.487
3.728LeuAsn: 3.728 ± 1.646
9.786LeuPro: 9.786 ± 1.308
3.262LeuGln: 3.262 ± 0.636
8.388LeuArg: 8.388 ± 3.84
5.592LeuSer: 5.592 ± 1.317
6.99LeuThr: 6.99 ± 3.979
5.126LeuVal: 5.126 ± 1.467
0.466LeuTrp: 0.466 ± 0.244
3.728LeuTyr: 3.728 ± 1.297
0.0LeuXaa: 0.0 ± 0.0
Met
3.262MetAla: 3.262 ± 1.023
0.0MetCys: 0.0 ± 0.0
1.398MetAsp: 1.398 ± 0.731
0.932MetGlu: 0.932 ± 0.487
0.932MetPhe: 0.932 ± 0.487
0.932MetGly: 0.932 ± 0.609
0.932MetHis: 0.932 ± 0.487
0.466MetIle: 0.466 ± 0.244
0.466MetLys: 0.466 ± 0.244
1.398MetLeu: 1.398 ± 0.731
0.466MetMet: 0.466 ± 0.244
0.932MetAsn: 0.932 ± 0.487
0.466MetPro: 0.466 ± 0.244
0.932MetGln: 0.932 ± 1.128
0.932MetArg: 0.932 ± 0.487
1.398MetSer: 1.398 ± 1.065
0.0MetThr: 0.0 ± 0.0
0.466MetVal: 0.466 ± 0.244
0.0MetTrp: 0.0 ± 0.0
0.466MetTyr: 0.466 ± 0.244
0.0MetXaa: 0.0 ± 0.0
Asn
4.66AsnAla: 4.66 ± 1.134
2.33AsnCys: 2.33 ± 2.126
2.796AsnAsp: 2.796 ± 1.037
2.33AsnGlu: 2.33 ± 1.218
1.398AsnPhe: 1.398 ± 0.731
1.398AsnGly: 1.398 ± 0.731
1.398AsnHis: 1.398 ± 0.731
3.262AsnIle: 3.262 ± 0.907
0.466AsnLys: 0.466 ± 0.244
3.262AsnLeu: 3.262 ± 1.108
0.0AsnMet: 0.0 ± 0.0
1.398AsnAsn: 1.398 ± 3.846
3.728AsnPro: 3.728 ± 0.749
0.932AsnGln: 0.932 ± 1.483
1.398AsnArg: 1.398 ± 0.731
2.33AsnSer: 2.33 ± 1.893
3.262AsnThr: 3.262 ± 0.636
2.796AsnVal: 2.796 ± 0.606
0.932AsnTrp: 0.932 ± 0.609
2.796AsnTyr: 2.796 ± 3.254
0.0AsnXaa: 0.0 ± 0.0
Pro
4.194ProAla: 4.194 ± 2.71
0.0ProCys: 0.0 ± 0.0
3.728ProAsp: 3.728 ± 2.366
5.592ProGlu: 5.592 ± 2.387
3.728ProPhe: 3.728 ± 2.389
3.728ProGly: 3.728 ± 1.395
3.262ProHis: 3.262 ± 4.064
3.728ProIle: 3.728 ± 1.395
6.99ProLys: 6.99 ± 3.655
4.66ProLeu: 4.66 ± 6.509
0.0ProMet: 0.0 ± 0.873
2.796ProAsn: 2.796 ± 1.216
5.592ProPro: 5.592 ± 3.461
2.33ProGln: 2.33 ± 1.218
3.262ProArg: 3.262 ± 1.706
4.194ProSer: 4.194 ± 0.938
8.388ProThr: 8.388 ± 2.408
3.262ProVal: 3.262 ± 1.96
0.932ProTrp: 0.932 ± 0.487
1.864ProTyr: 1.864 ± 0.758
0.0ProXaa: 0.0 ± 0.0
Gln
4.66GlnAla: 4.66 ± 1.919
0.466GlnCys: 0.466 ± 0.244
1.864GlnAsp: 1.864 ± 0.758
3.728GlnGlu: 3.728 ± 1.395
2.33GlnPhe: 2.33 ± 1.218
2.33GlnGly: 2.33 ± 1.218
0.932GlnHis: 0.932 ± 0.856
4.194GlnIle: 4.194 ± 1.689
0.466GlnLys: 0.466 ± 0.244
3.262GlnLeu: 3.262 ± 0.899
1.864GlnMet: 1.864 ± 0.937
0.466GlnAsn: 0.466 ± 0.244
2.796GlnPro: 2.796 ± 1.215
2.796GlnGln: 2.796 ± 1.216
2.33GlnArg: 2.33 ± 1.116
1.864GlnSer: 1.864 ± 0.941
6.058GlnThr: 6.058 ± 1.679
1.864GlnVal: 1.864 ± 0.975
0.932GlnTrp: 0.932 ± 0.487
0.466GlnTyr: 0.466 ± 0.244
0.0GlnXaa: 0.0 ± 0.0
Arg
6.99ArgAla: 6.99 ± 1.972
0.0ArgCys: 0.0 ± 0.0
3.262ArgAsp: 3.262 ± 1.108
4.66ArgGlu: 4.66 ± 0.614
2.33ArgPhe: 2.33 ± 1.218
3.728ArgGly: 3.728 ± 1.205
1.864ArgHis: 1.864 ± 2.831
0.932ArgIle: 0.932 ± 0.487
2.33ArgLys: 2.33 ± 0.82
6.99ArgLeu: 6.99 ± 1.987
0.466ArgMet: 0.466 ± 0.244
1.864ArgAsn: 1.864 ± 0.697
1.864ArgPro: 1.864 ± 2.421
1.864ArgGln: 1.864 ± 0.697
6.058ArgArg: 6.058 ± 1.679
4.194ArgSer: 4.194 ± 2.427
4.194ArgThr: 4.194 ± 1.007
2.33ArgVal: 2.33 ± 0.85
0.466ArgTrp: 0.466 ± 0.244
1.864ArgTyr: 1.864 ± 0.697
0.0ArgXaa: 0.0 ± 0.0
Ser
2.33SerAla: 2.33 ± 1.222
1.398SerCys: 1.398 ± 1.366
2.33SerAsp: 2.33 ± 0.67
4.66SerGlu: 4.66 ± 2.273
3.262SerPhe: 3.262 ± 3.018
3.262SerGly: 3.262 ± 2.689
2.796SerHis: 2.796 ± 3.092
3.262SerIle: 3.262 ± 1.285
5.592SerLys: 5.592 ± 2.166
4.66SerLeu: 4.66 ± 3.315
0.466SerMet: 0.466 ± 0.581
2.796SerAsn: 2.796 ± 1.14
3.262SerPro: 3.262 ± 1.48
3.262SerGln: 3.262 ± 1.354
1.864SerArg: 1.864 ± 0.975
5.592SerSer: 5.592 ± 1.434
5.592SerThr: 5.592 ± 3.063
2.796SerVal: 2.796 ± 1.107
0.932SerTrp: 0.932 ± 0.856
1.398SerTyr: 1.398 ± 0.771
0.0SerXaa: 0.0 ± 0.0
Thr
6.524ThrAla: 6.524 ± 2.224
1.398ThrCys: 1.398 ± 1.865
1.398ThrAsp: 1.398 ± 0.608
2.33ThrGlu: 2.33 ± 0.85
5.592ThrPhe: 5.592 ± 0.799
2.796ThrGly: 2.796 ± 1.037
3.262ThrHis: 3.262 ± 1.706
2.33ThrIle: 2.33 ± 1.218
3.262ThrLys: 3.262 ± 0.899
9.32ThrLeu: 9.32 ± 1.224
2.33ThrMet: 2.33 ± 1.218
4.66ThrAsn: 4.66 ± 1.304
7.922ThrPro: 7.922 ± 2.716
3.728ThrGln: 3.728 ± 1.463
6.99ThrArg: 6.99 ± 3.464
5.592ThrSer: 5.592 ± 2.092
3.728ThrThr: 3.728 ± 0.749
3.262ThrVal: 3.262 ± 1.411
0.932ThrTrp: 0.932 ± 0.487
2.33ThrTyr: 2.33 ± 1.218
0.0ThrXaa: 0.0 ± 0.0
Val
2.33ValAla: 2.33 ± 2.231
1.398ValCys: 1.398 ± 1.065
1.398ValAsp: 1.398 ± 1.009
1.864ValGlu: 1.864 ± 0.975
1.398ValPhe: 1.398 ± 0.731
2.33ValGly: 2.33 ± 2.173
0.932ValHis: 0.932 ± 0.487
2.796ValIle: 2.796 ± 2.152
3.262ValLys: 3.262 ± 1.285
6.058ValLeu: 6.058 ± 4.409
1.398ValMet: 1.398 ± 0.731
2.796ValAsn: 2.796 ± 1.143
2.796ValPro: 2.796 ± 1.037
3.262ValGln: 3.262 ± 1.706
0.932ValArg: 0.932 ± 0.487
1.398ValSer: 1.398 ± 0.771
5.126ValThr: 5.126 ± 1.549
2.796ValVal: 2.796 ± 4.124
0.0ValTrp: 0.0 ± 0.0
0.466ValTyr: 0.466 ± 0.244
0.0ValXaa: 0.0 ± 0.0
Trp
1.398TrpAla: 1.398 ± 0.608
0.0TrpCys: 0.0 ± 0.0
0.932TrpAsp: 0.932 ± 0.856
0.932TrpGlu: 0.932 ± 0.487
0.932TrpPhe: 0.932 ± 1.121
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.466TrpIle: 0.466 ± 0.244
1.864TrpLys: 1.864 ± 0.975
0.932TrpLeu: 0.932 ± 0.487
0.0TrpMet: 0.0 ± 0.0
0.466TrpAsn: 0.466 ± 0.701
0.0TrpPro: 0.0 ± 0.0
1.398TrpGln: 1.398 ± 0.608
0.932TrpArg: 0.932 ± 0.487
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.796TrpVal: 2.796 ± 1.462
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.262TyrAla: 3.262 ± 1.285
0.0TyrCys: 0.0 ± 0.0
0.932TyrAsp: 0.932 ± 0.487
1.398TyrGlu: 1.398 ± 0.771
0.932TyrPhe: 0.932 ± 0.609
1.398TyrGly: 1.398 ± 0.731
0.932TyrHis: 0.932 ± 0.609
1.398TyrIle: 1.398 ± 1.84
1.398TyrLys: 1.398 ± 1.333
3.262TyrLeu: 3.262 ± 1.245
1.398TyrMet: 1.398 ± 0.688
0.932TyrAsn: 0.932 ± 0.487
0.932TyrPro: 0.932 ± 0.856
1.398TyrGln: 1.398 ± 0.731
2.796TyrArg: 2.796 ± 1.75
1.398TyrSer: 1.398 ± 0.731
4.194TyrThr: 4.194 ± 0.634
0.932TyrVal: 0.932 ± 1.128
0.0TyrTrp: 0.0 ± 0.0
0.466TyrTyr: 0.466 ± 0.244
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2147 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski