Amino acid dipepetide frequency for Mycetocola zhujimingii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.371AlaAla: 17.371 ± 0.229
0.555AlaCys: 0.555 ± 0.028
7.601AlaAsp: 7.601 ± 0.104
7.878AlaGlu: 7.878 ± 0.11
3.778AlaPhe: 3.778 ± 0.066
11.272AlaGly: 11.272 ± 0.137
2.03AlaHis: 2.03 ± 0.052
6.191AlaIle: 6.191 ± 0.092
2.922AlaLys: 2.922 ± 0.07
13.119AlaLeu: 13.119 ± 0.158
2.592AlaMet: 2.592 ± 0.046
2.518AlaAsn: 2.518 ± 0.058
5.828AlaPro: 5.828 ± 0.1
3.483AlaGln: 3.483 ± 0.059
8.15AlaArg: 8.15 ± 0.113
7.796AlaSer: 7.796 ± 0.098
7.605AlaThr: 7.605 ± 0.104
10.9AlaVal: 10.9 ± 0.154
1.711AlaTrp: 1.711 ± 0.039
2.146AlaTyr: 2.146 ± 0.056
0.0AlaXaa: 0.0 ± 0.0
Cys
0.579CysAla: 0.579 ± 0.026
0.038CysCys: 0.038 ± 0.007
0.279CysAsp: 0.279 ± 0.017
0.214CysGlu: 0.214 ± 0.015
0.167CysPhe: 0.167 ± 0.015
0.535CysGly: 0.535 ± 0.028
0.11CysHis: 0.11 ± 0.011
0.203CysIle: 0.203 ± 0.015
0.064CysLys: 0.064 ± 0.009
0.44CysLeu: 0.44 ± 0.02
0.069CysMet: 0.069 ± 0.009
0.095CysAsn: 0.095 ± 0.011
0.26CysPro: 0.26 ± 0.02
0.12CysGln: 0.12 ± 0.011
0.317CysArg: 0.317 ± 0.02
0.354CysSer: 0.354 ± 0.024
0.326CysThr: 0.326 ± 0.02
0.432CysVal: 0.432 ± 0.022
0.08CysTrp: 0.08 ± 0.01
0.088CysTyr: 0.088 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
8.602AspAla: 8.602 ± 0.114
0.228AspCys: 0.228 ± 0.016
4.074AspAsp: 4.074 ± 0.087
4.297AspGlu: 4.297 ± 0.082
1.833AspPhe: 1.833 ± 0.044
5.851AspGly: 5.851 ± 0.093
1.043AspHis: 1.043 ± 0.034
2.7AspIle: 2.7 ± 0.052
1.198AspLys: 1.198 ± 0.04
5.968AspLeu: 5.968 ± 0.092
0.833AspMet: 0.833 ± 0.03
1.289AspAsn: 1.289 ± 0.039
3.774AspPro: 3.774 ± 0.074
1.516AspGln: 1.516 ± 0.043
4.126AspArg: 4.126 ± 0.066
3.314AspSer: 3.314 ± 0.071
3.134AspThr: 3.134 ± 0.059
5.473AspVal: 5.473 ± 0.077
0.933AspTrp: 0.933 ± 0.03
1.312AspTyr: 1.312 ± 0.037
0.0AspXaa: 0.0 ± 0.0
Glu
6.759GluAla: 6.759 ± 0.094
0.259GluCys: 0.259 ± 0.018
2.638GluAsp: 2.638 ± 0.053
2.997GluGlu: 2.997 ± 0.075
1.893GluPhe: 1.893 ± 0.049
3.65GluGly: 3.65 ± 0.068
1.439GluHis: 1.439 ± 0.04
2.962GluIle: 2.962 ± 0.064
1.664GluLys: 1.664 ± 0.053
6.76GluLeu: 6.76 ± 0.11
0.956GluMet: 0.956 ± 0.037
1.553GluAsn: 1.553 ± 0.041
3.093GluPro: 3.093 ± 0.067
2.166GluGln: 2.166 ± 0.055
4.835GluArg: 4.835 ± 0.082
3.731GluSer: 3.731 ± 0.058
3.337GluThr: 3.337 ± 0.064
4.262GluVal: 4.262 ± 0.079
0.863GluTrp: 0.863 ± 0.03
1.291GluTyr: 1.291 ± 0.042
0.0GluXaa: 0.0 ± 0.0
Phe
4.276PheAla: 4.276 ± 0.081
0.181PheCys: 0.181 ± 0.015
2.484PheAsp: 2.484 ± 0.05
1.937PheGlu: 1.937 ± 0.043
1.242PhePhe: 1.242 ± 0.044
3.549PheGly: 3.549 ± 0.062
0.532PheHis: 0.532 ± 0.025
1.445PheIle: 1.445 ± 0.044
0.516PheLys: 0.516 ± 0.025
3.102PheLeu: 3.102 ± 0.061
0.487PheMet: 0.487 ± 0.024
0.835PheAsn: 0.835 ± 0.03
1.437PhePro: 1.437 ± 0.04
0.819PheGln: 0.819 ± 0.029
1.762PheArg: 1.762 ± 0.047
2.204PheSer: 2.204 ± 0.051
2.226PheThr: 2.226 ± 0.049
2.935PheVal: 2.935 ± 0.053
0.497PheTrp: 0.497 ± 0.02
0.721PheTyr: 0.721 ± 0.028
0.0PheXaa: 0.0 ± 0.0
Gly
9.808GlyAla: 9.808 ± 0.128
0.573GlyCys: 0.573 ± 0.025
4.84GlyAsp: 4.84 ± 0.085
4.844GlyGlu: 4.844 ± 0.082
3.363GlyPhe: 3.363 ± 0.067
7.258GlyGly: 7.258 ± 0.102
1.843GlyHis: 1.843 ± 0.051
5.204GlyIle: 5.204 ± 0.08
2.47GlyLys: 2.47 ± 0.059
8.648GlyLeu: 8.648 ± 0.115
1.876GlyMet: 1.876 ± 0.048
2.1GlyAsn: 2.1 ± 0.059
3.64GlyPro: 3.64 ± 0.062
2.672GlyGln: 2.672 ± 0.052
5.525GlyArg: 5.525 ± 0.082
5.72GlySer: 5.72 ± 0.093
5.606GlyThr: 5.606 ± 0.09
7.547GlyVal: 7.547 ± 0.095
1.52GlyTrp: 1.52 ± 0.04
2.258GlyTyr: 2.258 ± 0.051
0.0GlyXaa: 0.0 ± 0.0
His
2.08HisAla: 2.08 ± 0.049
0.104HisCys: 0.104 ± 0.01
1.183HisAsp: 1.183 ± 0.038
1.039HisGlu: 1.039 ± 0.035
0.555HisPhe: 0.555 ± 0.026
1.789HisGly: 1.789 ± 0.044
0.502HisHis: 0.502 ± 0.025
0.822HisIle: 0.822 ± 0.032
0.369HisLys: 0.369 ± 0.02
1.861HisLeu: 1.861 ± 0.053
0.296HisMet: 0.296 ± 0.02
0.44HisAsn: 0.44 ± 0.025
1.406HisPro: 1.406 ± 0.044
0.476HisGln: 0.476 ± 0.023
1.363HisArg: 1.363 ± 0.039
1.184HisSer: 1.184 ± 0.041
1.006HisThr: 1.006 ± 0.036
1.483HisVal: 1.483 ± 0.039
0.289HisTrp: 0.289 ± 0.017
0.422HisTyr: 0.422 ± 0.022
0.0HisXaa: 0.0 ± 0.0
Ile
7.044IleAla: 7.044 ± 0.098
0.236IleCys: 0.236 ± 0.017
3.729IleAsp: 3.729 ± 0.066
3.073IleGlu: 3.073 ± 0.066
1.492IlePhe: 1.492 ± 0.046
4.955IleGly: 4.955 ± 0.094
0.717IleHis: 0.717 ± 0.03
2.246IleIle: 2.246 ± 0.06
0.953IleLys: 0.953 ± 0.036
4.338IleLeu: 4.338 ± 0.085
0.7IleMet: 0.7 ± 0.027
1.119IleAsn: 1.119 ± 0.039
2.649IlePro: 2.649 ± 0.064
1.098IleGln: 1.098 ± 0.037
3.06IleArg: 3.06 ± 0.049
2.862IleSer: 2.862 ± 0.056
3.131IleThr: 3.131 ± 0.063
4.803IleVal: 4.803 ± 0.088
0.558IleTrp: 0.558 ± 0.024
0.941IleTyr: 0.941 ± 0.033
0.0IleXaa: 0.0 ± 0.0
Lys
2.647LysAla: 2.647 ± 0.058
0.072LysCys: 0.072 ± 0.008
1.229LysAsp: 1.229 ± 0.036
1.115LysGlu: 1.115 ± 0.046
0.62LysPhe: 0.62 ± 0.027
1.671LysGly: 1.671 ± 0.049
0.534LysHis: 0.534 ± 0.022
1.118LysIle: 1.118 ± 0.037
1.049LysLys: 1.049 ± 0.046
2.254LysLeu: 2.254 ± 0.053
0.455LysMet: 0.455 ± 0.022
0.709LysAsn: 0.709 ± 0.03
1.449LysPro: 1.449 ± 0.044
0.828LysGln: 0.828 ± 0.033
1.892LysArg: 1.892 ± 0.05
1.414LysSer: 1.414 ± 0.04
1.615LysThr: 1.615 ± 0.045
1.82LysVal: 1.82 ± 0.057
0.283LysTrp: 0.283 ± 0.018
0.566LysTyr: 0.566 ± 0.028
0.0LysXaa: 0.0 ± 0.0
Leu
13.986LeuAla: 13.986 ± 0.169
0.531LeuCys: 0.531 ± 0.025
6.549LeuAsp: 6.549 ± 0.114
5.299LeuGlu: 5.299 ± 0.083
3.246LeuPhe: 3.246 ± 0.064
9.256LeuGly: 9.256 ± 0.11
1.709LeuHis: 1.709 ± 0.043
5.101LeuIle: 5.101 ± 0.099
2.123LeuLys: 2.123 ± 0.049
9.898LeuLeu: 9.898 ± 0.149
1.625LeuMet: 1.625 ± 0.042
2.215LeuAsn: 2.215 ± 0.053
5.32LeuPro: 5.32 ± 0.081
2.401LeuGln: 2.401 ± 0.053
6.498LeuArg: 6.498 ± 0.099
6.601LeuSer: 6.601 ± 0.083
6.651LeuThr: 6.651 ± 0.09
9.154LeuVal: 9.154 ± 0.12
1.318LeuTrp: 1.318 ± 0.04
1.821LeuTyr: 1.821 ± 0.044
0.0LeuXaa: 0.0 ± 0.0
Met
2.105MetAla: 2.105 ± 0.046
0.093MetCys: 0.093 ± 0.009
0.785MetAsp: 0.785 ± 0.03
0.643MetGlu: 0.643 ± 0.029
0.572MetPhe: 0.572 ± 0.028
1.264MetGly: 1.264 ± 0.037
0.35MetHis: 0.35 ± 0.019
0.922MetIle: 0.922 ± 0.03
0.519MetLys: 0.519 ± 0.023
1.899MetLeu: 1.899 ± 0.044
0.301MetMet: 0.301 ± 0.02
0.527MetAsn: 0.527 ± 0.024
1.152MetPro: 1.152 ± 0.036
0.527MetGln: 0.527 ± 0.026
1.242MetArg: 1.242 ± 0.036
1.469MetSer: 1.469 ± 0.041
1.721MetThr: 1.721 ± 0.038
1.382MetVal: 1.382 ± 0.039
0.185MetTrp: 0.185 ± 0.015
0.277MetTyr: 0.277 ± 0.019
0.0MetXaa: 0.0 ± 0.0
Asn
2.76AsnAla: 2.76 ± 0.06
0.131AsnCys: 0.131 ± 0.012
1.459AsnAsp: 1.459 ± 0.044
1.234AsnGlu: 1.234 ± 0.043
0.823AsnPhe: 0.823 ± 0.031
2.384AsnGly: 2.384 ± 0.058
0.39AsnHis: 0.39 ± 0.022
1.102AsnIle: 1.102 ± 0.035
0.526AsnLys: 0.526 ± 0.024
2.201AsnLeu: 2.201 ± 0.05
0.41AsnMet: 0.41 ± 0.019
0.634AsnAsn: 0.634 ± 0.03
1.84AsnPro: 1.84 ± 0.049
0.66AsnGln: 0.66 ± 0.028
1.503AsnArg: 1.503 ± 0.045
1.298AsnSer: 1.298 ± 0.043
1.357AsnThr: 1.357 ± 0.038
1.897AsnVal: 1.897 ± 0.051
0.392AsnTrp: 0.392 ± 0.021
0.627AsnTyr: 0.627 ± 0.026
0.0AsnXaa: 0.0 ± 0.0
Pro
6.532ProAla: 6.532 ± 0.085
0.186ProCys: 0.186 ± 0.014
3.894ProAsp: 3.894 ± 0.065
3.883ProGlu: 3.883 ± 0.072
1.731ProPhe: 1.731 ± 0.046
4.821ProGly: 4.821 ± 0.079
0.991ProHis: 0.991 ± 0.03
2.23ProIle: 2.23 ± 0.053
1.168ProLys: 1.168 ± 0.037
4.846ProLeu: 4.846 ± 0.078
0.823ProMet: 0.823 ± 0.031
1.27ProAsn: 1.27 ± 0.037
2.254ProPro: 2.254 ± 0.066
1.51ProGln: 1.51 ± 0.044
3.039ProArg: 3.039 ± 0.054
3.207ProSer: 3.207 ± 0.062
3.371ProThr: 3.371 ± 0.066
4.89ProVal: 4.89 ± 0.075
0.795ProTrp: 0.795 ± 0.026
1.081ProTyr: 1.081 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
3.323GlnAla: 3.323 ± 0.062
0.095GlnCys: 0.095 ± 0.009
1.301GlnAsp: 1.301 ± 0.039
1.258GlnGlu: 1.258 ± 0.047
0.967GlnPhe: 0.967 ± 0.032
1.992GlnGly: 1.992 ± 0.048
0.558GlnHis: 0.558 ± 0.024
1.422GlnIle: 1.422 ± 0.044
0.81GlnLys: 0.81 ± 0.035
3.319GlnLeu: 3.319 ± 0.061
0.521GlnMet: 0.521 ± 0.024
0.719GlnAsn: 0.719 ± 0.027
1.665GlnPro: 1.665 ± 0.046
1.089GlnGln: 1.089 ± 0.041
2.239GlnArg: 2.239 ± 0.05
1.7GlnSer: 1.7 ± 0.043
1.498GlnThr: 1.498 ± 0.04
2.444GlnVal: 2.444 ± 0.046
0.398GlnTrp: 0.398 ± 0.023
0.642GlnTyr: 0.642 ± 0.029
0.0GlnXaa: 0.0 ± 0.0
Arg
7.562ArgAla: 7.562 ± 0.116
0.262ArgCys: 0.262 ± 0.017
4.025ArgAsp: 4.025 ± 0.068
4.09ArgGlu: 4.09 ± 0.066
2.45ArgPhe: 2.45 ± 0.053
4.857ArgGly: 4.857 ± 0.075
1.406ArgHis: 1.406 ± 0.039
3.484ArgIle: 3.484 ± 0.059
1.616ArgLys: 1.616 ± 0.046
6.811ArgLeu: 6.811 ± 0.098
1.65ArgMet: 1.65 ± 0.041
1.621ArgAsn: 1.621 ± 0.047
3.169ArgPro: 3.169 ± 0.056
2.103ArgGln: 2.103 ± 0.043
5.396ArgArg: 5.396 ± 0.093
4.221ArgSer: 4.221 ± 0.071
4.01ArgThr: 4.01 ± 0.068
5.698ArgVal: 5.698 ± 0.079
1.047ArgTrp: 1.047 ± 0.036
1.485ArgTyr: 1.485 ± 0.041
0.0ArgXaa: 0.0 ± 0.0
Ser
7.565SerAla: 7.565 ± 0.103
0.279SerCys: 0.279 ± 0.017
3.771SerAsp: 3.771 ± 0.07
3.24SerGlu: 3.24 ± 0.056
2.12SerPhe: 2.12 ± 0.049
6.164SerGly: 6.164 ± 0.09
1.145SerHis: 1.145 ± 0.038
3.182SerIle: 3.182 ± 0.061
1.41SerLys: 1.41 ± 0.04
5.953SerLeu: 5.953 ± 0.086
1.266SerMet: 1.266 ± 0.037
1.438SerAsn: 1.438 ± 0.043
3.344SerPro: 3.344 ± 0.066
1.642SerGln: 1.642 ± 0.044
4.162SerArg: 4.162 ± 0.072
4.054SerSer: 4.054 ± 0.086
4.15SerThr: 4.15 ± 0.069
5.498SerVal: 5.498 ± 0.081
0.957SerTrp: 0.957 ± 0.031
1.34SerTyr: 1.34 ± 0.041
0.0SerXaa: 0.0 ± 0.0
Thr
7.876ThrAla: 7.876 ± 0.095
0.261ThrCys: 0.261 ± 0.017
4.098ThrAsp: 4.098 ± 0.068
3.524ThrGlu: 3.524 ± 0.077
1.987ThrPhe: 1.987 ± 0.055
6.022ThrGly: 6.022 ± 0.097
1.136ThrHis: 1.136 ± 0.038
3.019ThrIle: 3.019 ± 0.063
1.393ThrLys: 1.393 ± 0.045
6.261ThrLeu: 6.261 ± 0.081
0.972ThrMet: 0.972 ± 0.033
1.439ThrAsn: 1.439 ± 0.048
3.885ThrPro: 3.885 ± 0.07
1.5ThrGln: 1.5 ± 0.045
3.635ThrArg: 3.635 ± 0.069
3.708ThrSer: 3.708 ± 0.058
4.049ThrThr: 4.049 ± 0.078
6.242ThrVal: 6.242 ± 0.103
0.889ThrTrp: 0.889 ± 0.036
1.18ThrTyr: 1.18 ± 0.04
0.0ThrXaa: 0.0 ± 0.0
Val
10.841ValAla: 10.841 ± 0.135
0.477ValCys: 0.477 ± 0.024
5.525ValAsp: 5.525 ± 0.077
4.738ValGlu: 4.738 ± 0.074
2.915ValPhe: 2.915 ± 0.053
7.103ValGly: 7.103 ± 0.09
1.57ValHis: 1.57 ± 0.044
4.835ValIle: 4.835 ± 0.077
1.797ValLys: 1.797 ± 0.052
9.44ValLeu: 9.44 ± 0.137
1.546ValMet: 1.546 ± 0.041
2.091ValAsn: 2.091 ± 0.047
4.555ValPro: 4.555 ± 0.082
2.173ValGln: 2.173 ± 0.049
5.471ValArg: 5.471 ± 0.078
5.588ValSer: 5.588 ± 0.086
6.21ValThr: 6.21 ± 0.099
8.343ValVal: 8.343 ± 0.131
1.114ValTrp: 1.114 ± 0.041
1.543ValTyr: 1.543 ± 0.046
0.0ValXaa: 0.0 ± 0.0
Trp
1.474TrpAla: 1.474 ± 0.043
0.084TrpCys: 0.084 ± 0.01
0.737TrpAsp: 0.737 ± 0.032
0.649TrpGlu: 0.649 ± 0.025
0.578TrpPhe: 0.578 ± 0.024
0.976TrpGly: 0.976 ± 0.03
0.364TrpHis: 0.364 ± 0.019
0.717TrpIle: 0.717 ± 0.032
0.385TrpLys: 0.385 ± 0.022
1.84TrpLeu: 1.84 ± 0.045
0.284TrpMet: 0.284 ± 0.019
0.472TrpAsn: 0.472 ± 0.023
0.682TrpPro: 0.682 ± 0.027
0.569TrpGln: 0.569 ± 0.028
1.13TrpArg: 1.13 ± 0.034
0.903TrpSer: 0.903 ± 0.029
0.887TrpThr: 0.887 ± 0.035
1.115TrpVal: 1.115 ± 0.036
0.319TrpTrp: 0.319 ± 0.017
0.306TrpTyr: 0.306 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.26TyrAla: 2.26 ± 0.055
0.125TyrCys: 0.125 ± 0.011
1.299TyrAsp: 1.299 ± 0.042
1.152TyrGlu: 1.152 ± 0.04
0.856TyrPhe: 0.856 ± 0.027
1.945TyrGly: 1.945 ± 0.05
0.3TyrHis: 0.3 ± 0.018
0.798TyrIle: 0.798 ± 0.03
0.387TyrLys: 0.387 ± 0.018
2.344TyrLeu: 2.344 ± 0.051
0.274TyrMet: 0.274 ± 0.017
0.541TyrAsn: 0.541 ± 0.029
1.118TyrPro: 1.118 ± 0.039
0.606TyrGln: 0.606 ± 0.026
1.618TyrArg: 1.618 ± 0.047
1.354TyrSer: 1.354 ± 0.042
1.186TyrThr: 1.186 ± 0.039
1.559TyrVal: 1.559 ± 0.042
0.326TyrTrp: 0.326 ± 0.02
0.498TyrTyr: 0.498 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2928 proteins (942499 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski