Amino acid dipepetide frequency for Mus musculus polyomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.22AlaAla: 7.22 ± 1.149
2.166AlaCys: 2.166 ± 0.915
3.61AlaAsp: 3.61 ± 1.554
1.444AlaGlu: 1.444 ± 0.771
2.888AlaPhe: 2.888 ± 0.676
2.888AlaGly: 2.888 ± 0.996
0.0AlaHis: 0.0 ± 0.0
2.888AlaIle: 2.888 ± 1.072
5.054AlaLys: 5.054 ± 1.871
6.498AlaLeu: 6.498 ± 1.495
1.444AlaMet: 1.444 ± 1.498
1.444AlaAsn: 1.444 ± 1.714
4.332AlaPro: 4.332 ± 1.24
3.61AlaGln: 3.61 ± 1.146
3.61AlaArg: 3.61 ± 2.317
0.722AlaSer: 0.722 ± 0.639
2.166AlaThr: 2.166 ± 0.924
5.054AlaVal: 5.054 ± 1.371
1.444AlaTrp: 1.444 ± 0.505
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.166CysAla: 2.166 ± 0.915
0.722CysCys: 0.722 ± 0.447
2.166CysAsp: 2.166 ± 0.709
0.722CysGlu: 0.722 ± 0.447
0.722CysPhe: 0.722 ± 0.447
0.722CysGly: 0.722 ± 0.447
2.166CysHis: 2.166 ± 0.777
0.0CysIle: 0.0 ± 0.0
4.332CysLys: 4.332 ± 1.465
5.054CysLeu: 5.054 ± 3.207
0.722CysMet: 0.722 ± 0.447
2.888CysAsn: 2.888 ± 1.589
0.0CysPro: 0.0 ± 0.0
0.722CysGln: 0.722 ± 0.447
1.444CysArg: 1.444 ± 0.795
1.444CysSer: 1.444 ± 0.895
0.722CysThr: 0.722 ± 0.447
0.722CysVal: 0.722 ± 0.447
0.0CysTrp: 0.0 ± 0.0
2.166CysTyr: 2.166 ± 1.884
0.0CysXaa: 0.0 ± 0.0
Asp
2.888AspAla: 2.888 ± 0.539
0.0AspCys: 0.0 ± 0.0
2.888AspAsp: 2.888 ± 1.79
2.888AspGlu: 2.888 ± 1.201
3.61AspPhe: 3.61 ± 0.842
5.054AspGly: 5.054 ± 1.871
2.166AspHis: 2.166 ± 0.915
4.332AspIle: 4.332 ± 0.705
4.332AspLys: 4.332 ± 1.386
7.942AspLeu: 7.942 ± 2.83
3.61AspMet: 3.61 ± 1.535
2.166AspAsn: 2.166 ± 1.061
3.61AspPro: 3.61 ± 2.242
0.722AspGln: 0.722 ± 0.447
1.444AspArg: 1.444 ± 0.795
2.888AspSer: 2.888 ± 1.01
1.444AspThr: 1.444 ± 0.937
1.444AspVal: 1.444 ± 0.505
1.444AspTrp: 1.444 ± 1.296
1.444AspTyr: 1.444 ± 1.074
0.0AspXaa: 0.0 ± 0.0
Glu
5.054GluAla: 5.054 ± 2.777
1.444GluCys: 1.444 ± 0.895
3.61GluAsp: 3.61 ± 0.738
5.054GluGlu: 5.054 ± 1.894
2.166GluPhe: 2.166 ± 1.342
3.61GluGly: 3.61 ± 1.146
0.722GluHis: 0.722 ± 0.447
0.722GluIle: 0.722 ± 0.447
2.888GluLys: 2.888 ± 1.201
7.22GluLeu: 7.22 ± 1.523
2.166GluMet: 2.166 ± 0.69
6.498GluAsn: 6.498 ± 0.578
2.166GluPro: 2.166 ± 0.915
3.61GluGln: 3.61 ± 1.129
2.888GluArg: 2.888 ± 0.539
5.054GluSer: 5.054 ± 1.72
2.888GluThr: 2.888 ± 1.769
3.61GluVal: 3.61 ± 2.307
1.444GluTrp: 1.444 ± 0.895
2.888GluTyr: 2.888 ± 1.79
0.0GluXaa: 0.0 ± 0.0
Phe
2.166PheAla: 2.166 ± 0.924
2.166PheCys: 2.166 ± 0.915
3.61PheAsp: 3.61 ± 2.237
4.332PheGlu: 4.332 ± 1.393
1.444PhePhe: 1.444 ± 0.505
2.166PheGly: 2.166 ± 1.515
1.444PheHis: 1.444 ± 0.505
5.054PheIle: 5.054 ± 1.734
2.166PheLys: 2.166 ± 1.342
2.888PheLeu: 2.888 ± 0.676
1.444PheMet: 1.444 ± 0.895
1.444PheAsn: 1.444 ± 0.895
5.776PhePro: 5.776 ± 1.16
1.444PheGln: 1.444 ± 0.795
1.444PheArg: 1.444 ± 1.278
3.61PheSer: 3.61 ± 2.307
1.444PheThr: 1.444 ± 0.895
1.444PheVal: 1.444 ± 1.296
0.722PheTrp: 0.722 ± 0.857
0.722PheTyr: 0.722 ± 0.639
0.0PheXaa: 0.0 ± 0.0
Gly
2.888GlyAla: 2.888 ± 1.408
0.722GlyCys: 0.722 ± 0.447
2.166GlyAsp: 2.166 ± 1.356
1.444GlyGlu: 1.444 ± 1.278
2.166GlyPhe: 2.166 ± 1.917
5.776GlyGly: 5.776 ± 0.854
0.722GlyHis: 0.722 ± 0.857
3.61GlyIle: 3.61 ± 0.773
3.61GlyLys: 3.61 ± 1.482
7.942GlyLeu: 7.942 ± 3.08
0.0GlyMet: 0.0 ± 0.0
2.166GlyAsn: 2.166 ± 0.915
2.166GlyPro: 2.166 ± 1.061
5.054GlyGln: 5.054 ± 1.102
2.166GlyArg: 2.166 ± 1.567
2.888GlySer: 2.888 ± 1.005
2.166GlyThr: 2.166 ± 0.709
5.054GlyVal: 5.054 ± 2.023
0.0GlyTrp: 0.0 ± 0.0
0.722GlyTyr: 0.722 ± 0.909
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.722HisCys: 0.722 ± 0.447
0.0HisAsp: 0.0 ± 0.0
0.722HisGlu: 0.722 ± 0.447
2.888HisPhe: 2.888 ± 1.181
0.722HisGly: 0.722 ± 0.857
0.722HisHis: 0.722 ± 0.447
0.0HisIle: 0.0 ± 0.0
2.166HisLys: 2.166 ± 0.915
3.61HisLeu: 3.61 ± 1.565
0.0HisMet: 0.0 ± 0.0
0.722HisAsn: 0.722 ± 0.447
2.166HisPro: 2.166 ± 1.07
1.444HisGln: 1.444 ± 0.795
0.722HisArg: 0.722 ± 0.447
1.444HisSer: 1.444 ± 0.937
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.444IleAla: 1.444 ± 0.795
0.722IleCys: 0.722 ± 0.447
2.888IleAsp: 2.888 ± 0.924
5.054IleGlu: 5.054 ± 1.477
1.444IlePhe: 1.444 ± 0.895
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
2.166IleIle: 2.166 ± 1.648
1.444IleLys: 1.444 ± 0.505
5.776IleLeu: 5.776 ± 1.267
0.722IleMet: 0.722 ± 0.72
3.61IleAsn: 3.61 ± 1.129
2.888IlePro: 2.888 ± 1.072
2.166IleGln: 2.166 ± 0.62
0.722IleArg: 0.722 ± 0.639
5.776IleSer: 5.776 ± 1.338
4.332IleThr: 4.332 ± 2.123
5.054IleVal: 5.054 ± 1.045
1.444IleTrp: 1.444 ± 1.296
2.888IleTyr: 2.888 ± 1.072
0.0IleXaa: 0.0 ± 0.0
Lys
5.776LysAla: 5.776 ± 0.931
2.166LysCys: 2.166 ± 1.648
3.61LysAsp: 3.61 ± 1.605
4.332LysGlu: 4.332 ± 1.91
2.888LysPhe: 2.888 ± 1.01
4.332LysGly: 4.332 ± 0.526
1.444LysHis: 1.444 ± 0.895
3.61LysIle: 3.61 ± 1.437
5.054LysLys: 5.054 ± 2.344
6.498LysLeu: 6.498 ± 1.408
2.166LysMet: 2.166 ± 1.061
2.166LysAsn: 2.166 ± 1.061
2.166LysPro: 2.166 ± 1.061
0.0LysGln: 0.0 ± 0.0
3.61LysArg: 3.61 ± 1.554
2.166LysSer: 2.166 ± 0.915
5.054LysThr: 5.054 ± 1.553
3.61LysVal: 3.61 ± 1.679
0.0LysTrp: 0.0 ± 0.0
2.888LysTyr: 2.888 ± 1.072
0.0LysXaa: 0.0 ± 0.0
Leu
3.61LeuAla: 3.61 ± 1.244
2.888LeuCys: 2.888 ± 0.676
5.776LeuAsp: 5.776 ± 1.102
9.386LeuGlu: 9.386 ± 2.992
5.054LeuPhe: 5.054 ± 1.553
3.61LeuGly: 3.61 ± 2.317
0.0LeuHis: 0.0 ± 0.0
5.054LeuIle: 5.054 ± 1.476
4.332LeuLys: 4.332 ± 0.526
11.552LeuLeu: 11.552 ± 3.004
5.054LeuMet: 5.054 ± 1.476
7.22LeuAsn: 7.22 ± 2.276
7.942LeuPro: 7.942 ± 1.905
5.776LeuGln: 5.776 ± 1.658
3.61LeuArg: 3.61 ± 0.842
10.108LeuSer: 10.108 ± 3.407
5.776LeuThr: 5.776 ± 2.341
1.444LeuVal: 1.444 ± 0.505
0.722LeuTrp: 0.722 ± 0.909
8.664LeuTyr: 8.664 ± 2.64
0.0LeuXaa: 0.0 ± 0.0
Met
3.61MetAla: 3.61 ± 0.738
0.0MetCys: 0.0 ± 0.0
2.166MetAsp: 2.166 ± 0.915
3.61MetGlu: 3.61 ± 0.604
0.722MetPhe: 0.722 ± 0.447
1.444MetGly: 1.444 ± 0.505
2.166MetHis: 2.166 ± 0.777
0.722MetIle: 0.722 ± 0.639
0.0MetLys: 0.0 ± 0.0
2.166MetLeu: 2.166 ± 0.62
0.722MetMet: 0.722 ± 0.639
0.0MetAsn: 0.0 ± 0.0
3.61MetPro: 3.61 ± 1.146
0.722MetGln: 0.722 ± 0.909
2.888MetArg: 2.888 ± 1.005
0.0MetSer: 0.0 ± 0.0
1.444MetThr: 1.444 ± 0.505
2.166MetVal: 2.166 ± 0.709
0.722MetTrp: 0.722 ± 0.639
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.444AsnAla: 1.444 ± 0.771
3.61AsnCys: 3.61 ± 1.437
0.722AsnAsp: 0.722 ± 0.447
6.498AsnGlu: 6.498 ± 2.518
4.332AsnPhe: 4.332 ± 1.446
1.444AsnGly: 1.444 ± 0.505
1.444AsnHis: 1.444 ± 0.795
2.888AsnIle: 2.888 ± 0.676
5.054AsnLys: 5.054 ± 1.554
3.61AsnLeu: 3.61 ± 1.605
0.722AsnMet: 0.722 ± 0.447
2.166AsnAsn: 2.166 ± 0.777
1.444AsnPro: 1.444 ± 1.278
1.444AsnGln: 1.444 ± 0.771
0.722AsnArg: 0.722 ± 0.447
2.166AsnSer: 2.166 ± 1.342
3.61AsnThr: 3.61 ± 1.535
0.722AsnVal: 0.722 ± 0.447
1.444AsnTrp: 1.444 ± 0.771
2.166AsnTyr: 2.166 ± 0.62
0.0AsnXaa: 0.0 ± 0.0
Pro
2.888ProAla: 2.888 ± 0.996
2.888ProCys: 2.888 ± 1.614
6.498ProAsp: 6.498 ± 1.978
1.444ProGlu: 1.444 ± 0.895
2.888ProPhe: 2.888 ± 1.005
5.054ProGly: 5.054 ± 1.371
0.0ProHis: 0.0 ± 0.0
1.444ProIle: 1.444 ± 0.937
5.054ProLys: 5.054 ± 2.053
3.61ProLeu: 3.61 ± 0.604
2.166ProMet: 2.166 ± 0.777
1.444ProAsn: 1.444 ± 0.895
5.054ProPro: 5.054 ± 1.553
2.888ProGln: 2.888 ± 1.408
3.61ProArg: 3.61 ± 2.307
3.61ProSer: 3.61 ± 0.738
2.166ProThr: 2.166 ± 0.709
4.332ProVal: 4.332 ± 2.123
0.0ProTrp: 0.0 ± 0.0
2.166ProTyr: 2.166 ± 0.62
0.0ProXaa: 0.0 ± 0.0
Gln
2.888GlnAla: 2.888 ± 0.539
0.722GlnCys: 0.722 ± 0.447
2.166GlnAsp: 2.166 ± 0.777
3.61GlnGlu: 3.61 ± 0.842
0.722GlnPhe: 0.722 ± 0.447
2.166GlnGly: 2.166 ± 0.709
0.722GlnHis: 0.722 ± 0.447
5.054GlnIle: 5.054 ± 1.235
2.888GlnLys: 2.888 ± 0.539
4.332GlnLeu: 4.332 ± 2.401
2.888GlnMet: 2.888 ± 0.539
1.444GlnAsn: 1.444 ± 0.505
2.166GlnPro: 2.166 ± 0.62
2.888GlnGln: 2.888 ± 1.408
3.61GlnArg: 3.61 ± 1.628
2.888GlnSer: 2.888 ± 1.201
0.722GlnThr: 0.722 ± 0.639
2.888GlnVal: 2.888 ± 1.902
0.0GlnTrp: 0.0 ± 0.0
2.888GlnTyr: 2.888 ± 1.005
0.0GlnXaa: 0.0 ± 0.0
Arg
2.888ArgAla: 2.888 ± 1.005
0.722ArgCys: 0.722 ± 0.639
1.444ArgAsp: 1.444 ± 0.505
2.166ArgGlu: 2.166 ± 1.07
3.61ArgPhe: 3.61 ± 1.129
0.722ArgGly: 0.722 ± 0.639
0.722ArgHis: 0.722 ± 0.447
2.166ArgIle: 2.166 ± 1.061
2.888ArgLys: 2.888 ± 0.924
6.498ArgLeu: 6.498 ± 2.332
1.444ArgMet: 1.444 ± 0.505
2.888ArgAsn: 2.888 ± 1.23
1.444ArgPro: 1.444 ± 0.505
1.444ArgGln: 1.444 ± 0.771
3.61ArgArg: 3.61 ± 1.129
2.888ArgSer: 2.888 ± 1.408
1.444ArgThr: 1.444 ± 1.278
3.61ArgVal: 3.61 ± 1.605
0.722ArgTrp: 0.722 ± 0.857
5.054ArgTyr: 5.054 ± 1.53
0.0ArgXaa: 0.0 ± 0.0
Ser
6.498SerAla: 6.498 ± 1.123
1.444SerCys: 1.444 ± 0.505
4.332SerAsp: 4.332 ± 1.555
6.498SerGlu: 6.498 ± 1.661
1.444SerPhe: 1.444 ± 0.895
0.722SerGly: 0.722 ± 0.857
0.722SerHis: 0.722 ± 0.857
2.888SerIle: 2.888 ± 1.01
1.444SerLys: 1.444 ± 0.895
7.942SerLeu: 7.942 ± 1.181
1.444SerMet: 1.444 ± 0.505
2.166SerAsn: 2.166 ± 0.709
2.888SerPro: 2.888 ± 0.539
5.776SerGln: 5.776 ± 2.646
1.444SerArg: 1.444 ± 0.895
3.61SerSer: 3.61 ± 1.146
2.888SerThr: 2.888 ± 1.005
4.332SerVal: 4.332 ± 0.705
1.444SerTrp: 1.444 ± 1.296
2.166SerTyr: 2.166 ± 0.924
0.0SerXaa: 0.0 ± 0.0
Thr
0.722ThrAla: 0.722 ± 0.639
2.166ThrCys: 2.166 ± 0.709
2.166ThrAsp: 2.166 ± 1.648
1.444ThrGlu: 1.444 ± 0.505
0.0ThrPhe: 0.0 ± 0.0
4.332ThrGly: 4.332 ± 0.705
0.0ThrHis: 0.0 ± 0.0
3.61ThrIle: 3.61 ± 1.146
2.166ThrLys: 2.166 ± 1.567
5.776ThrLeu: 5.776 ± 1.078
0.0ThrMet: 0.0 ± 0.0
2.166ThrAsn: 2.166 ± 1.061
4.332ThrPro: 4.332 ± 0.526
5.776ThrGln: 5.776 ± 1.28
2.888ThrArg: 2.888 ± 0.676
1.444ThrSer: 1.444 ± 1.714
3.61ThrThr: 3.61 ± 1.535
2.166ThrVal: 2.166 ± 1.917
0.0ThrTrp: 0.0 ± 0.0
2.888ThrTyr: 2.888 ± 0.539
0.0ThrXaa: 0.0 ± 0.0
Val
2.888ValAla: 2.888 ± 1.01
0.722ValCys: 0.722 ± 0.909
2.888ValAsp: 2.888 ± 0.539
2.888ValGlu: 2.888 ± 1.678
2.888ValPhe: 2.888 ± 1.201
4.332ValGly: 4.332 ± 3.102
1.444ValHis: 1.444 ± 0.795
2.166ValIle: 2.166 ± 1.342
4.332ValLys: 4.332 ± 1.515
3.61ValLeu: 3.61 ± 1.535
0.0ValMet: 0.0 ± 0.0
3.61ValAsn: 3.61 ± 1.605
2.166ValPro: 2.166 ± 1.061
1.444ValGln: 1.444 ± 0.937
2.888ValArg: 2.888 ± 1.01
6.498ValSer: 6.498 ± 1.123
2.888ValThr: 2.888 ± 1.408
3.61ValVal: 3.61 ± 1.535
1.444ValTrp: 1.444 ± 0.795
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.444TrpAla: 1.444 ± 1.714
0.0TrpCys: 0.0 ± 0.0
0.722TrpAsp: 0.722 ± 0.447
1.444TrpGlu: 1.444 ± 0.937
1.444TrpPhe: 1.444 ± 0.795
0.722TrpGly: 0.722 ± 0.909
0.0TrpHis: 0.0 ± 0.0
0.722TrpIle: 0.722 ± 0.909
2.166TrpLys: 2.166 ± 0.924
0.722TrpLeu: 0.722 ± 0.447
1.444TrpMet: 1.444 ± 1.296
0.722TrpAsn: 0.722 ± 0.909
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.722TrpSer: 0.722 ± 0.639
0.0TrpThr: 0.0 ± 0.0
0.722TrpVal: 0.722 ± 0.447
0.722TrpTrp: 0.722 ± 0.447
0.722TrpTyr: 0.722 ± 0.857
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.722TyrAla: 0.722 ± 0.447
3.61TyrCys: 3.61 ± 1.654
2.888TyrAsp: 2.888 ± 1.874
0.722TyrGlu: 0.722 ± 0.447
3.61TyrPhe: 3.61 ± 1.525
3.61TyrGly: 3.61 ± 0.604
1.444TyrHis: 1.444 ± 0.771
1.444TyrIle: 1.444 ± 1.296
2.166TyrLys: 2.166 ± 0.915
4.332TyrLeu: 4.332 ± 1.167
0.0TyrMet: 0.0 ± 0.0
0.722TyrAsn: 0.722 ± 0.447
2.888TyrPro: 2.888 ± 0.996
0.722TyrGln: 0.722 ± 0.447
5.054TyrArg: 5.054 ± 1.284
2.166TyrSer: 2.166 ± 0.62
2.888TyrThr: 2.888 ± 1.01
0.722TyrVal: 0.722 ± 0.857
0.722TyrTrp: 0.722 ± 0.447
0.722TyrTyr: 0.722 ± 0.857
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1386 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski