Amino acid dipepetide frequency for Mycobacterium phage Corndog (Mycobacteriophage Corndog)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.382AlaAla: 14.382 ± 1.067
1.411AlaCys: 1.411 ± 0.281
5.689AlaAsp: 5.689 ± 0.53
8.374AlaGlu: 8.374 ± 0.785
3.322AlaPhe: 3.322 ± 0.412
8.738AlaGly: 8.738 ± 0.744
2.003AlaHis: 2.003 ± 0.34
4.961AlaIle: 4.961 ± 0.468
3.595AlaLys: 3.595 ± 0.486
8.602AlaLeu: 8.602 ± 0.703
2.867AlaMet: 2.867 ± 0.334
2.913AlaAsn: 2.913 ± 0.345
4.324AlaPro: 4.324 ± 0.493
3.641AlaGln: 3.641 ± 0.477
7.145AlaArg: 7.145 ± 0.743
4.87AlaSer: 4.87 ± 0.515
6.053AlaThr: 6.053 ± 0.58
7.737AlaVal: 7.737 ± 0.675
1.912AlaTrp: 1.912 ± 0.276
2.913AlaTyr: 2.913 ± 0.388
0.0AlaXaa: 0.0 ± 0.0
Cys
1.456CysAla: 1.456 ± 0.388
0.319CysCys: 0.319 ± 0.144
1.001CysAsp: 1.001 ± 0.245
0.683CysGlu: 0.683 ± 0.186
0.228CysPhe: 0.228 ± 0.094
1.502CysGly: 1.502 ± 0.352
0.364CysHis: 0.364 ± 0.163
0.546CysIle: 0.546 ± 0.175
0.273CysLys: 0.273 ± 0.128
0.637CysLeu: 0.637 ± 0.212
0.182CysMet: 0.182 ± 0.094
0.319CysAsn: 0.319 ± 0.121
1.411CysPro: 1.411 ± 0.343
0.364CysGln: 0.364 ± 0.126
1.047CysArg: 1.047 ± 0.261
0.683CysSer: 0.683 ± 0.215
0.455CysThr: 0.455 ± 0.166
0.91CysVal: 0.91 ± 0.211
0.228CysTrp: 0.228 ± 0.102
0.319CysTyr: 0.319 ± 0.12
0.0CysXaa: 0.0 ± 0.0
Asp
6.599AspAla: 6.599 ± 0.51
1.138AspCys: 1.138 ± 0.241
4.551AspAsp: 4.551 ± 0.434
4.278AspGlu: 4.278 ± 0.429
1.593AspPhe: 1.593 ± 0.297
6.235AspGly: 6.235 ± 0.547
0.819AspHis: 0.819 ± 0.229
2.822AspIle: 2.822 ± 0.459
1.866AspLys: 1.866 ± 0.298
5.188AspLeu: 5.188 ± 0.409
1.638AspMet: 1.638 ± 0.304
1.547AspAsn: 1.547 ± 0.261
4.005AspPro: 4.005 ± 0.397
1.684AspGln: 1.684 ± 0.304
4.142AspArg: 4.142 ± 0.388
2.503AspSer: 2.503 ± 0.386
3.687AspThr: 3.687 ± 0.389
4.278AspVal: 4.278 ± 0.445
1.638AspTrp: 1.638 ± 0.273
1.82AspTyr: 1.82 ± 0.307
0.0AspXaa: 0.0 ± 0.0
Glu
6.417GluAla: 6.417 ± 0.623
0.865GluCys: 0.865 ± 0.2
3.641GluAsp: 3.641 ± 0.373
3.732GluGlu: 3.732 ± 0.492
2.094GluPhe: 2.094 ± 0.304
4.642GluGly: 4.642 ± 0.479
1.638GluHis: 1.638 ± 0.312
2.594GluIle: 2.594 ± 0.388
2.23GluLys: 2.23 ± 0.271
5.826GluLeu: 5.826 ± 0.627
1.866GluMet: 1.866 ± 0.237
2.003GluAsn: 2.003 ± 0.234
3.869GluPro: 3.869 ± 0.514
2.913GluGln: 2.913 ± 0.375
4.824GluArg: 4.824 ± 0.464
4.187GluSer: 4.187 ± 0.396
3.732GluThr: 3.732 ± 0.429
6.099GluVal: 6.099 ± 0.534
1.183GluTrp: 1.183 ± 0.239
1.684GluTyr: 1.684 ± 0.276
0.0GluXaa: 0.0 ± 0.0
Phe
3.049PheAla: 3.049 ± 0.359
0.319PheCys: 0.319 ± 0.116
2.64PheAsp: 2.64 ± 0.303
1.729PheGlu: 1.729 ± 0.306
0.865PhePhe: 0.865 ± 0.181
3.322PheGly: 3.322 ± 0.558
0.501PheHis: 0.501 ± 0.145
1.047PheIle: 1.047 ± 0.239
0.865PheLys: 0.865 ± 0.18
1.638PheLeu: 1.638 ± 0.255
0.819PheMet: 0.819 ± 0.192
0.865PheAsn: 0.865 ± 0.158
1.274PhePro: 1.274 ± 0.233
0.819PheGln: 0.819 ± 0.194
2.276PheArg: 2.276 ± 0.266
1.684PheSer: 1.684 ± 0.283
1.912PheThr: 1.912 ± 0.316
2.276PheVal: 2.276 ± 0.298
0.592PheTrp: 0.592 ± 0.165
0.956PheTyr: 0.956 ± 0.224
0.0PheXaa: 0.0 ± 0.0
Gly
7.919GlyAla: 7.919 ± 0.896
0.91GlyCys: 0.91 ± 0.228
5.37GlyAsp: 5.37 ± 0.49
5.644GlyGlu: 5.644 ± 0.53
3.186GlyPhe: 3.186 ± 0.397
7.874GlyGly: 7.874 ± 1.001
1.957GlyHis: 1.957 ± 0.391
4.369GlyIle: 4.369 ± 0.615
3.641GlyLys: 3.641 ± 0.454
6.599GlyLeu: 6.599 ± 0.493
1.82GlyMet: 1.82 ± 0.271
3.368GlyAsn: 3.368 ± 0.479
5.188GlyPro: 5.188 ± 0.491
2.64GlyGln: 2.64 ± 0.32
5.553GlyArg: 5.553 ± 0.454
5.279GlySer: 5.279 ± 0.736
5.006GlyThr: 5.006 ± 0.562
6.508GlyVal: 6.508 ± 0.486
1.684GlyTrp: 1.684 ± 0.289
2.64GlyTyr: 2.64 ± 0.404
0.0GlyXaa: 0.0 ± 0.0
His
1.638HisAla: 1.638 ± 0.289
0.319HisCys: 0.319 ± 0.148
1.229HisAsp: 1.229 ± 0.248
1.274HisGlu: 1.274 ± 0.246
0.364HisPhe: 0.364 ± 0.132
1.502HisGly: 1.502 ± 0.273
0.592HisHis: 0.592 ± 0.16
1.001HisIle: 1.001 ± 0.202
0.319HisLys: 0.319 ± 0.107
1.866HisLeu: 1.866 ± 0.328
0.364HisMet: 0.364 ± 0.129
0.364HisAsn: 0.364 ± 0.153
1.502HisPro: 1.502 ± 0.233
0.546HisGln: 0.546 ± 0.143
2.003HisArg: 2.003 ± 0.342
0.91HisSer: 0.91 ± 0.25
1.274HisThr: 1.274 ± 0.191
1.229HisVal: 1.229 ± 0.266
0.592HisTrp: 0.592 ± 0.183
0.455HisTyr: 0.455 ± 0.153
0.0HisXaa: 0.0 ± 0.0
Ile
5.461IleAla: 5.461 ± 0.516
0.319IleCys: 0.319 ± 0.138
3.186IleAsp: 3.186 ± 0.426
3.595IleGlu: 3.595 ± 0.38
0.956IlePhe: 0.956 ± 0.224
4.233IleGly: 4.233 ± 0.446
0.455IleHis: 0.455 ± 0.139
1.866IleIle: 1.866 ± 0.287
1.456IleLys: 1.456 ± 0.232
2.64IleLeu: 2.64 ± 0.407
0.728IleMet: 0.728 ± 0.165
1.229IleAsn: 1.229 ± 0.243
3.277IlePro: 3.277 ± 0.323
1.274IleGln: 1.274 ± 0.256
3.049IleArg: 3.049 ± 0.373
2.367IleSer: 2.367 ± 0.361
3.049IleThr: 3.049 ± 0.369
3.687IleVal: 3.687 ± 0.396
1.092IleTrp: 1.092 ± 0.211
0.819IleTyr: 0.819 ± 0.219
0.0IleXaa: 0.0 ± 0.0
Lys
3.823LysAla: 3.823 ± 0.491
0.364LysCys: 0.364 ± 0.146
1.638LysAsp: 1.638 ± 0.246
2.003LysGlu: 2.003 ± 0.329
1.092LysPhe: 1.092 ± 0.217
2.958LysGly: 2.958 ± 0.33
0.592LysHis: 0.592 ± 0.164
1.638LysIle: 1.638 ± 0.311
1.411LysLys: 1.411 ± 0.341
3.231LysLeu: 3.231 ± 0.351
1.047LysMet: 1.047 ± 0.206
0.637LysAsn: 0.637 ± 0.207
2.549LysPro: 2.549 ± 0.431
1.138LysGln: 1.138 ± 0.199
2.094LysArg: 2.094 ± 0.315
1.502LysSer: 1.502 ± 0.249
2.276LysThr: 2.276 ± 0.322
3.368LysVal: 3.368 ± 0.417
0.637LysTrp: 0.637 ± 0.141
1.092LysTyr: 1.092 ± 0.229
0.0LysXaa: 0.0 ± 0.0
Leu
9.057LeuAla: 9.057 ± 0.628
1.138LeuCys: 1.138 ± 0.307
5.644LeuAsp: 5.644 ± 0.566
4.87LeuGlu: 4.87 ± 0.495
2.458LeuPhe: 2.458 ± 0.35
6.827LeuGly: 6.827 ± 0.646
1.229LeuHis: 1.229 ± 0.258
2.867LeuIle: 2.867 ± 0.39
2.776LeuLys: 2.776 ± 0.504
5.37LeuLeu: 5.37 ± 0.575
2.003LeuMet: 2.003 ± 0.299
2.594LeuAsn: 2.594 ± 0.413
5.097LeuPro: 5.097 ± 0.496
1.775LeuGln: 1.775 ± 0.282
5.644LeuArg: 5.644 ± 0.484
5.006LeuSer: 5.006 ± 0.48
5.052LeuThr: 5.052 ± 0.456
5.461LeuVal: 5.461 ± 0.465
1.32LeuTrp: 1.32 ± 0.243
1.957LeuTyr: 1.957 ± 0.347
0.0LeuXaa: 0.0 ± 0.0
Met
2.822MetAla: 2.822 ± 0.369
0.137MetCys: 0.137 ± 0.076
0.683MetAsp: 0.683 ± 0.151
1.502MetGlu: 1.502 ± 0.239
0.865MetPhe: 0.865 ± 0.154
1.274MetGly: 1.274 ± 0.279
0.455MetHis: 0.455 ± 0.128
1.001MetIle: 1.001 ± 0.191
0.865MetLys: 0.865 ± 0.178
1.82MetLeu: 1.82 ± 0.261
1.047MetMet: 1.047 ± 0.24
0.637MetAsn: 0.637 ± 0.172
1.82MetPro: 1.82 ± 0.265
0.637MetGln: 0.637 ± 0.164
2.276MetArg: 2.276 ± 0.33
2.321MetSer: 2.321 ± 0.361
2.503MetThr: 2.503 ± 0.272
1.957MetVal: 1.957 ± 0.331
0.683MetTrp: 0.683 ± 0.146
0.319MetTyr: 0.319 ± 0.129
0.0MetXaa: 0.0 ± 0.0
Asn
2.913AsnAla: 2.913 ± 0.43
0.228AsnCys: 0.228 ± 0.114
1.775AsnAsp: 1.775 ± 0.287
1.866AsnGlu: 1.866 ± 0.278
1.092AsnPhe: 1.092 ± 0.243
3.231AsnGly: 3.231 ± 0.382
0.501AsnHis: 0.501 ± 0.116
1.092AsnIle: 1.092 ± 0.196
0.819AsnLys: 0.819 ± 0.176
2.776AsnLeu: 2.776 ± 0.39
0.91AsnMet: 0.91 ± 0.213
1.411AsnAsn: 1.411 ± 0.254
2.185AsnPro: 2.185 ± 0.255
0.683AsnGln: 0.683 ± 0.181
2.503AsnArg: 2.503 ± 0.312
1.274AsnSer: 1.274 ± 0.276
2.367AsnThr: 2.367 ± 0.373
1.775AsnVal: 1.775 ± 0.253
0.819AsnTrp: 0.819 ± 0.183
0.637AsnTyr: 0.637 ± 0.169
0.0AsnXaa: 0.0 ± 0.0
Pro
5.507ProAla: 5.507 ± 0.546
0.819ProCys: 0.819 ± 0.229
4.46ProAsp: 4.46 ± 0.5
6.008ProGlu: 6.008 ± 0.665
1.547ProPhe: 1.547 ± 0.307
6.053ProGly: 6.053 ± 0.914
1.365ProHis: 1.365 ± 0.291
2.321ProIle: 2.321 ± 0.31
1.957ProLys: 1.957 ± 0.263
3.869ProLeu: 3.869 ± 0.381
1.638ProMet: 1.638 ± 0.275
2.776ProAsn: 2.776 ± 0.369
4.096ProPro: 4.096 ± 0.509
2.503ProGln: 2.503 ± 0.403
2.913ProArg: 2.913 ± 0.381
3.459ProSer: 3.459 ± 0.403
3.687ProThr: 3.687 ± 0.456
4.187ProVal: 4.187 ± 0.448
1.593ProTrp: 1.593 ± 0.246
1.138ProTyr: 1.138 ± 0.236
0.0ProXaa: 0.0 ± 0.0
Gln
3.778GlnAla: 3.778 ± 0.478
0.319GlnCys: 0.319 ± 0.107
1.593GlnAsp: 1.593 ± 0.25
1.775GlnGlu: 1.775 ± 0.208
0.956GlnPhe: 0.956 ± 0.203
2.412GlnGly: 2.412 ± 0.329
1.183GlnHis: 1.183 ± 0.191
1.957GlnIle: 1.957 ± 0.299
1.365GlnLys: 1.365 ± 0.277
2.822GlnLeu: 2.822 ± 0.406
0.865GlnMet: 0.865 ± 0.194
0.774GlnAsn: 0.774 ± 0.227
1.957GlnPro: 1.957 ± 0.286
1.593GlnGln: 1.593 ± 0.363
2.503GlnArg: 2.503 ± 0.294
1.684GlnSer: 1.684 ± 0.311
1.274GlnThr: 1.274 ± 0.231
2.685GlnVal: 2.685 ± 0.319
0.819GlnTrp: 0.819 ± 0.198
0.774GlnTyr: 0.774 ± 0.213
0.0GlnXaa: 0.0 ± 0.0
Arg
6.963ArgAla: 6.963 ± 0.586
1.183ArgCys: 1.183 ± 0.303
4.233ArgAsp: 4.233 ± 0.456
4.46ArgGlu: 4.46 ± 0.495
2.412ArgPhe: 2.412 ± 0.347
5.644ArgGly: 5.644 ± 0.519
1.092ArgHis: 1.092 ± 0.283
3.504ArgIle: 3.504 ± 0.428
3.413ArgLys: 3.413 ± 0.452
5.598ArgLeu: 5.598 ± 0.583
1.82ArgMet: 1.82 ± 0.317
2.776ArgAsn: 2.776 ± 0.289
3.504ArgPro: 3.504 ± 0.483
2.549ArgGln: 2.549 ± 0.356
6.463ArgArg: 6.463 ± 0.867
3.277ArgSer: 3.277 ± 0.366
4.005ArgThr: 4.005 ± 0.586
5.006ArgVal: 5.006 ± 0.47
2.048ArgTrp: 2.048 ± 0.349
1.684ArgTyr: 1.684 ± 0.255
0.0ArgXaa: 0.0 ± 0.0
Ser
5.052SerAla: 5.052 ± 0.493
0.683SerCys: 0.683 ± 0.203
3.595SerAsp: 3.595 ± 0.392
3.641SerGlu: 3.641 ± 0.371
1.502SerPhe: 1.502 ± 0.375
5.644SerGly: 5.644 ± 0.484
1.047SerHis: 1.047 ± 0.232
2.64SerIle: 2.64 ± 0.32
2.185SerLys: 2.185 ± 0.325
3.869SerLeu: 3.869 ± 0.411
1.912SerMet: 1.912 ± 0.294
1.638SerAsn: 1.638 ± 0.237
3.732SerPro: 3.732 ± 0.319
2.094SerGln: 2.094 ± 0.293
2.549SerArg: 2.549 ± 0.371
2.503SerSer: 2.503 ± 0.439
3.14SerThr: 3.14 ± 0.354
3.413SerVal: 3.413 ± 0.366
1.502SerTrp: 1.502 ± 0.251
1.502SerTyr: 1.502 ± 0.271
0.0SerXaa: 0.0 ± 0.0
Thr
6.599ThrAla: 6.599 ± 0.678
0.865ThrCys: 0.865 ± 0.262
3.277ThrAsp: 3.277 ± 0.365
4.415ThrGlu: 4.415 ± 0.508
1.638ThrPhe: 1.638 ± 0.321
5.279ThrGly: 5.279 ± 0.477
0.91ThrHis: 0.91 ± 0.217
2.594ThrIle: 2.594 ± 0.343
2.048ThrLys: 2.048 ± 0.305
6.053ThrLeu: 6.053 ± 0.617
1.274ThrMet: 1.274 ± 0.221
1.593ThrAsn: 1.593 ± 0.251
4.961ThrPro: 4.961 ± 0.467
1.638ThrGln: 1.638 ± 0.309
4.324ThrArg: 4.324 ± 0.451
3.095ThrSer: 3.095 ± 0.291
2.958ThrThr: 2.958 ± 0.398
4.688ThrVal: 4.688 ± 0.459
0.91ThrTrp: 0.91 ± 0.198
1.638ThrTyr: 1.638 ± 0.253
0.0ThrXaa: 0.0 ± 0.0
Val
7.601ValAla: 7.601 ± 0.616
0.91ValCys: 0.91 ± 0.223
4.915ValAsp: 4.915 ± 0.494
4.278ValGlu: 4.278 ± 0.518
2.094ValPhe: 2.094 ± 0.297
6.372ValGly: 6.372 ± 0.708
1.502ValHis: 1.502 ± 0.278
3.641ValIle: 3.641 ± 0.405
2.822ValLys: 2.822 ± 0.399
6.235ValLeu: 6.235 ± 0.568
1.593ValMet: 1.593 ± 0.357
2.321ValAsn: 2.321 ± 0.381
4.187ValPro: 4.187 ± 0.589
2.412ValGln: 2.412 ± 0.274
5.689ValArg: 5.689 ± 0.575
4.233ValSer: 4.233 ± 0.409
5.37ValThr: 5.37 ± 0.537
6.008ValVal: 6.008 ± 0.657
1.411ValTrp: 1.411 ± 0.281
1.593ValTyr: 1.593 ± 0.223
0.0ValXaa: 0.0 ± 0.0
Trp
2.139TrpAla: 2.139 ± 0.269
0.455TrpCys: 0.455 ± 0.139
1.32TrpAsp: 1.32 ± 0.238
0.683TrpGlu: 0.683 ± 0.154
0.501TrpPhe: 0.501 ± 0.167
1.047TrpGly: 1.047 ± 0.24
0.683TrpHis: 0.683 ± 0.175
1.274TrpIle: 1.274 ± 0.249
0.637TrpLys: 0.637 ± 0.212
1.775TrpLeu: 1.775 ± 0.284
0.728TrpMet: 0.728 ± 0.175
0.228TrpAsn: 0.228 ± 0.088
1.638TrpPro: 1.638 ± 0.308
1.183TrpGln: 1.183 ± 0.229
2.23TrpArg: 2.23 ± 0.348
1.411TrpSer: 1.411 ± 0.302
1.274TrpThr: 1.274 ± 0.203
1.82TrpVal: 1.82 ± 0.327
0.546TrpTrp: 0.546 ± 0.157
0.364TrpTyr: 0.364 ± 0.142
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.276TyrAla: 2.276 ± 0.335
0.228TyrCys: 0.228 ± 0.092
1.638TyrAsp: 1.638 ± 0.28
1.229TyrGlu: 1.229 ± 0.249
0.683TyrPhe: 0.683 ± 0.174
2.367TyrGly: 2.367 ± 0.493
0.455TyrHis: 0.455 ± 0.16
1.001TyrIle: 1.001 ± 0.281
0.546TyrLys: 0.546 ± 0.152
1.729TyrLeu: 1.729 ± 0.3
0.455TyrMet: 0.455 ± 0.127
0.865TyrAsn: 0.865 ± 0.235
1.32TyrPro: 1.32 ± 0.233
1.001TyrGln: 1.001 ± 0.182
2.412TyrArg: 2.412 ± 0.375
1.593TyrSer: 1.593 ± 0.251
1.684TyrThr: 1.684 ± 0.277
2.094TyrVal: 2.094 ± 0.333
0.728TyrTrp: 0.728 ± 0.172
0.501TyrTyr: 0.501 ± 0.148
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 122 proteins (21973 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski