Amino acid dipepetide frequency for Spinach yellow vein Sikar virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.024AlaAla: 4.024 ± 2.101
1.006AlaCys: 1.006 ± 0.862
1.006AlaAsp: 1.006 ± 0.862
3.018AlaGlu: 3.018 ± 2.311
1.006AlaPhe: 1.006 ± 1.192
3.018AlaGly: 3.018 ± 1.567
1.006AlaHis: 1.006 ± 1.077
2.012AlaIle: 2.012 ± 1.053
3.018AlaLys: 3.018 ± 1.498
9.054AlaLeu: 9.054 ± 1.671
0.0AlaMet: 0.0 ± 0.0
1.006AlaAsn: 1.006 ± 0.77
3.018AlaPro: 3.018 ± 2.062
2.012AlaGln: 2.012 ± 1.54
3.018AlaArg: 3.018 ± 1.987
6.036AlaSer: 6.036 ± 2.92
4.024AlaThr: 4.024 ± 2.526
1.006AlaVal: 1.006 ± 1.049
3.018AlaTrp: 3.018 ± 2.311
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
2.012CysCys: 2.012 ± 2.098
0.0CysAsp: 0.0 ± 0.0
2.012CysGlu: 2.012 ± 1.172
3.018CysPhe: 3.018 ± 1.417
1.006CysGly: 1.006 ± 1.077
1.006CysHis: 1.006 ± 1.077
1.006CysIle: 1.006 ± 1.171
1.006CysLys: 1.006 ± 0.862
0.0CysLeu: 0.0 ± 0.0
1.006CysMet: 1.006 ± 1.049
1.006CysAsn: 1.006 ± 0.77
3.018CysPro: 3.018 ± 1.987
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.012CysSer: 2.012 ± 2.153
1.006CysThr: 1.006 ± 0.862
6.036CysVal: 6.036 ± 2.822
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.012AspAla: 2.012 ± 1.053
0.0AspCys: 0.0 ± 0.0
4.024AspAsp: 4.024 ± 2.137
2.012AspGlu: 2.012 ± 1.725
2.012AspPhe: 2.012 ± 0.884
1.006AspGly: 1.006 ± 0.77
0.0AspHis: 0.0 ± 0.0
4.024AspIle: 4.024 ± 1.935
0.0AspLys: 0.0 ± 0.0
4.024AspLeu: 4.024 ± 3.107
0.0AspMet: 0.0 ± 0.0
2.012AspAsn: 2.012 ± 0.884
4.024AspPro: 4.024 ± 2.208
3.018AspGln: 3.018 ± 2.402
1.006AspArg: 1.006 ± 0.862
4.024AspSer: 4.024 ± 1.768
4.024AspThr: 4.024 ± 3.463
7.042AspVal: 7.042 ± 3.5
2.012AspTrp: 2.012 ± 1.053
1.006AspTyr: 1.006 ± 0.77
0.0AspXaa: 0.0 ± 0.0
Glu
8.048GluAla: 8.048 ± 3.13
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
4.024GluGlu: 4.024 ± 2.106
2.012GluPhe: 2.012 ± 1.082
3.018GluGly: 3.018 ± 0.942
3.018GluHis: 3.018 ± 2.312
2.012GluIle: 2.012 ± 1.082
3.018GluLys: 3.018 ± 2.311
2.012GluLeu: 2.012 ± 1.279
0.0GluMet: 0.0 ± 0.0
6.036GluAsn: 6.036 ± 2.994
2.012GluPro: 2.012 ± 1.172
3.018GluGln: 3.018 ± 1.733
1.006GluArg: 1.006 ± 0.77
3.018GluSer: 3.018 ± 2.062
2.012GluThr: 2.012 ± 1.54
3.018GluVal: 3.018 ± 0.942
1.006GluTrp: 1.006 ± 0.77
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
2.012PheCys: 2.012 ± 0.884
4.024PheAsp: 4.024 ± 1.768
2.012PheGlu: 2.012 ± 1.172
1.006PhePhe: 1.006 ± 0.862
2.012PheGly: 2.012 ± 1.725
3.018PheHis: 3.018 ± 1.559
4.024PheIle: 4.024 ± 1.768
3.018PheLys: 3.018 ± 1.813
5.03PheLeu: 5.03 ± 3.597
1.006PheMet: 1.006 ± 0.77
4.024PheAsn: 4.024 ± 3.45
4.024PhePro: 4.024 ± 3.107
2.012PheGln: 2.012 ± 1.54
5.03PheArg: 5.03 ± 1.724
2.012PheSer: 2.012 ± 1.54
1.006PheThr: 1.006 ± 1.049
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.006PheTyr: 1.006 ± 0.862
0.0PheXaa: 0.0 ± 0.0
Gly
2.012GlyAla: 2.012 ± 1.54
2.012GlyCys: 2.012 ± 1.157
4.024GlyAsp: 4.024 ± 2.106
1.006GlyGlu: 1.006 ± 0.862
1.006GlyPhe: 1.006 ± 1.049
2.012GlyGly: 2.012 ± 1.725
0.0GlyHis: 0.0 ± 0.0
1.006GlyIle: 1.006 ± 1.192
8.048GlyLys: 8.048 ± 3.949
2.012GlyLeu: 2.012 ± 1.63
2.012GlyMet: 2.012 ± 1.03
0.0GlyAsn: 0.0 ± 0.0
2.012GlyPro: 2.012 ± 1.172
2.012GlyGln: 2.012 ± 1.725
1.006GlyArg: 1.006 ± 1.192
2.012GlySer: 2.012 ± 1.54
4.024GlyThr: 4.024 ± 2.751
0.0GlyVal: 0.0 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
1.006GlyTyr: 1.006 ± 1.049
0.0GlyXaa: 0.0 ± 0.0
His
6.036HisAla: 6.036 ± 1.682
2.012HisCys: 2.012 ± 1.553
1.006HisAsp: 1.006 ± 0.862
0.0HisGlu: 0.0 ± 0.0
4.024HisPhe: 4.024 ± 2.208
1.006HisGly: 1.006 ± 1.049
4.024HisHis: 4.024 ± 3.415
2.012HisIle: 2.012 ± 0.884
1.006HisLys: 1.006 ± 1.192
1.006HisLeu: 1.006 ± 0.77
0.0HisMet: 0.0 ± 0.0
3.018HisAsn: 3.018 ± 1.417
2.012HisPro: 2.012 ± 1.54
1.006HisGln: 1.006 ± 0.77
4.024HisArg: 4.024 ± 3.079
3.018HisSer: 3.018 ± 1.467
2.012HisThr: 2.012 ± 0.884
2.012HisVal: 2.012 ± 2.384
1.006HisTrp: 1.006 ± 1.192
3.018HisTyr: 3.018 ± 2.311
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.006IleCys: 1.006 ± 1.077
3.018IleAsp: 3.018 ± 2.311
2.012IleGlu: 2.012 ± 1.54
3.018IlePhe: 3.018 ± 2.311
2.012IleGly: 2.012 ± 1.274
2.012IleHis: 2.012 ± 1.327
5.03IleIle: 5.03 ± 1.365
5.03IleLys: 5.03 ± 2.529
3.018IleLeu: 3.018 ± 1.559
0.0IleMet: 0.0 ± 0.0
3.018IleAsn: 3.018 ± 1.559
3.018IlePro: 3.018 ± 1.509
3.018IleGln: 3.018 ± 1.186
8.048IleArg: 8.048 ± 3.935
6.036IleSer: 6.036 ± 2.221
3.018IleThr: 3.018 ± 2.505
4.024IleVal: 4.024 ± 1.788
4.024IleTrp: 4.024 ± 2.548
3.018IleTyr: 3.018 ± 1.186
0.0IleXaa: 0.0 ± 0.0
Lys
2.012LysAla: 2.012 ± 1.586
2.012LysCys: 2.012 ± 1.327
2.012LysAsp: 2.012 ± 1.54
3.018LysGlu: 3.018 ± 1.567
5.03LysPhe: 5.03 ± 2.338
3.018LysGly: 3.018 ± 1.986
4.024LysHis: 4.024 ± 3.081
3.018LysIle: 3.018 ± 2.587
3.018LysLys: 3.018 ± 1.733
2.012LysLeu: 2.012 ± 1.082
0.0LysMet: 0.0 ± 0.0
2.012LysAsn: 2.012 ± 0.884
2.012LysPro: 2.012 ± 0.884
0.0LysGln: 0.0 ± 0.0
1.006LysArg: 1.006 ± 0.862
4.024LysSer: 4.024 ± 2.101
3.018LysThr: 3.018 ± 1.186
5.03LysVal: 5.03 ± 2.591
1.006LysTrp: 1.006 ± 0.862
5.03LysTyr: 5.03 ± 2.187
0.0LysXaa: 0.0 ± 0.0
Leu
4.024LeuAla: 4.024 ± 1.616
3.018LeuCys: 3.018 ± 2.361
2.012LeuAsp: 2.012 ± 2.153
5.03LeuGlu: 5.03 ± 3.082
0.0LeuPhe: 0.0 ± 0.0
3.018LeuGly: 3.018 ± 1.386
1.006LeuHis: 1.006 ± 0.77
6.036LeuIle: 6.036 ± 3.283
6.036LeuLys: 6.036 ± 2.456
2.012LeuLeu: 2.012 ± 1.082
5.03LeuMet: 5.03 ± 2.633
3.018LeuAsn: 3.018 ± 0.942
4.024LeuPro: 4.024 ± 3.016
2.012LeuGln: 2.012 ± 1.082
4.024LeuArg: 4.024 ± 2.304
2.012LeuSer: 2.012 ± 1.63
4.024LeuThr: 4.024 ± 1.756
4.024LeuVal: 4.024 ± 2.343
0.0LeuTrp: 0.0 ± 0.0
1.006LeuTyr: 1.006 ± 0.862
0.0LeuXaa: 0.0 ± 0.0
Met
1.006MetAla: 1.006 ± 0.862
1.006MetCys: 1.006 ± 0.862
2.012MetAsp: 2.012 ± 1.725
1.006MetGlu: 1.006 ± 0.77
4.024MetPhe: 4.024 ± 2.314
2.012MetGly: 2.012 ± 1.279
1.006MetHis: 1.006 ± 1.192
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
3.018MetLeu: 3.018 ± 1.456
0.0MetMet: 0.0 ± 0.0
1.006MetAsn: 1.006 ± 1.192
2.012MetPro: 2.012 ± 1.279
0.0MetGln: 0.0 ± 0.0
2.012MetArg: 2.012 ± 1.63
3.018MetSer: 3.018 ± 2.366
3.018MetThr: 3.018 ± 1.774
0.0MetVal: 0.0 ± 0.0
2.012MetTrp: 2.012 ± 1.082
1.006MetTyr: 1.006 ± 0.77
0.0MetXaa: 0.0 ± 0.0
Asn
3.018AsnAla: 3.018 ± 1.416
1.006AsnCys: 1.006 ± 0.77
0.0AsnAsp: 0.0 ± 0.0
6.036AsnGlu: 6.036 ± 1.515
2.012AsnPhe: 2.012 ± 0.884
0.0AsnGly: 0.0 ± 0.0
6.036AsnHis: 6.036 ± 2.107
5.03AsnIle: 5.03 ± 2.338
0.0AsnLys: 0.0 ± 0.0
6.036AsnLeu: 6.036 ± 2.713
2.012AsnMet: 2.012 ± 1.615
3.018AsnAsn: 3.018 ± 1.567
4.024AsnPro: 4.024 ± 1.551
2.012AsnGln: 2.012 ± 1.725
3.018AsnArg: 3.018 ± 2.402
4.024AsnSer: 4.024 ± 1.551
2.012AsnThr: 2.012 ± 1.082
6.036AsnVal: 6.036 ± 3.625
0.0AsnTrp: 0.0 ± 0.0
3.018AsnTyr: 3.018 ± 1.77
0.0AsnXaa: 0.0 ± 0.0
Pro
3.018ProAla: 3.018 ± 1.928
4.024ProCys: 4.024 ± 0.996
4.024ProAsp: 4.024 ± 1.79
4.024ProGlu: 4.024 ± 2.197
3.018ProPhe: 3.018 ± 1.417
1.006ProGly: 1.006 ± 1.171
5.03ProHis: 5.03 ± 2.57
9.054ProIle: 9.054 ± 2.528
1.006ProLys: 1.006 ± 0.77
1.006ProLeu: 1.006 ± 1.049
2.012ProMet: 2.012 ± 1.053
6.036ProAsn: 6.036 ± 3.168
5.03ProPro: 5.03 ± 2.233
2.012ProGln: 2.012 ± 1.157
4.024ProArg: 4.024 ± 1.261
8.048ProSer: 8.048 ± 3.593
2.012ProThr: 2.012 ± 2.341
2.012ProVal: 2.012 ± 0.884
0.0ProTrp: 0.0 ± 0.0
1.006ProTyr: 1.006 ± 0.862
0.0ProXaa: 0.0 ± 0.0
Gln
3.018GlnAla: 3.018 ± 1.733
0.0GlnCys: 0.0 ± 0.0
2.012GlnAsp: 2.012 ± 0.884
3.018GlnGlu: 3.018 ± 1.567
3.018GlnPhe: 3.018 ± 1.813
1.006GlnGly: 1.006 ± 0.77
2.012GlnHis: 2.012 ± 1.157
1.006GlnIle: 1.006 ± 1.192
0.0GlnLys: 0.0 ± 0.0
2.012GlnLeu: 2.012 ± 2.098
2.012GlnMet: 2.012 ± 2.153
0.0GlnAsn: 0.0 ± 0.0
4.024GlnPro: 4.024 ± 2.646
3.018GlnGln: 3.018 ± 1.733
2.012GlnArg: 2.012 ± 1.053
6.036GlnSer: 6.036 ± 2.184
1.006GlnThr: 1.006 ± 1.171
3.018GlnVal: 3.018 ± 1.186
0.0GlnTrp: 0.0 ± 0.0
3.018GlnTyr: 3.018 ± 1.567
0.0GlnXaa: 0.0 ± 0.0
Arg
2.012ArgAla: 2.012 ± 1.082
1.006ArgCys: 1.006 ± 1.049
4.024ArgAsp: 4.024 ± 1.088
4.024ArgGlu: 4.024 ± 2.19
3.018ArgPhe: 3.018 ± 1.386
3.018ArgGly: 3.018 ± 1.733
3.018ArgHis: 3.018 ± 0.855
5.03ArgIle: 5.03 ± 1.277
3.018ArgLys: 3.018 ± 1.386
2.012ArgLeu: 2.012 ± 1.157
0.0ArgMet: 0.0 ± 0.0
2.012ArgAsn: 2.012 ± 1.082
6.036ArgPro: 6.036 ± 2.041
1.006ArgGln: 1.006 ± 1.049
6.036ArgArg: 6.036 ± 3.337
2.012ArgSer: 2.012 ± 1.157
2.012ArgThr: 2.012 ± 1.279
7.042ArgVal: 7.042 ± 2.732
0.0ArgTrp: 0.0 ± 0.0
2.012ArgTyr: 2.012 ± 1.172
0.0ArgXaa: 0.0 ± 0.0
Ser
1.006SerAla: 1.006 ± 0.77
0.0SerCys: 0.0 ± 0.0
5.03SerAsp: 5.03 ± 1.754
2.012SerGlu: 2.012 ± 1.342
4.024SerPhe: 4.024 ± 1.145
0.0SerGly: 0.0 ± 0.0
1.006SerHis: 1.006 ± 1.077
5.03SerIle: 5.03 ± 2.67
7.042SerLys: 7.042 ± 2.904
6.036SerLeu: 6.036 ± 3.112
2.012SerMet: 2.012 ± 2.341
5.03SerAsn: 5.03 ± 2.83
7.042SerPro: 7.042 ± 2.292
3.018SerGln: 3.018 ± 1.854
6.036SerArg: 6.036 ± 2.337
17.103SerSer: 17.103 ± 7.36
6.036SerThr: 6.036 ± 2.052
7.042SerVal: 7.042 ± 2.918
0.0SerTrp: 0.0 ± 0.0
2.012SerTyr: 2.012 ± 1.053
0.0SerXaa: 0.0 ± 0.0
Thr
2.012ThrAla: 2.012 ± 1.157
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
2.012ThrGly: 2.012 ± 0.884
4.024ThrHis: 4.024 ± 1.732
0.0ThrIle: 0.0 ± 0.0
3.018ThrLys: 3.018 ± 1.567
3.018ThrLeu: 3.018 ± 1.526
3.018ThrMet: 3.018 ± 1.407
4.024ThrAsn: 4.024 ± 1.594
6.036ThrPro: 6.036 ± 2.221
6.036ThrGln: 6.036 ± 3.343
2.012ThrArg: 2.012 ± 1.157
7.042ThrSer: 7.042 ± 5.865
2.012ThrThr: 2.012 ± 2.341
5.03ThrVal: 5.03 ± 1.837
0.0ThrTrp: 0.0 ± 0.0
3.018ThrTyr: 3.018 ± 1.987
0.0ThrXaa: 0.0 ± 0.0
Val
2.012ValAla: 2.012 ± 0.884
3.018ValCys: 3.018 ± 3.146
6.036ValAsp: 6.036 ± 2.932
2.012ValGlu: 2.012 ± 2.098
2.012ValPhe: 2.012 ± 1.274
5.03ValGly: 5.03 ± 2.19
1.006ValHis: 1.006 ± 1.049
6.036ValIle: 6.036 ± 2.909
5.03ValLys: 5.03 ± 2.187
4.024ValLeu: 4.024 ± 2.548
3.018ValMet: 3.018 ± 1.928
4.024ValAsn: 4.024 ± 1.694
4.024ValPro: 4.024 ± 1.788
4.024ValGln: 4.024 ± 2.236
4.024ValArg: 4.024 ± 2.526
3.018ValSer: 3.018 ± 1.567
5.03ValThr: 5.03 ± 2.272
6.036ValVal: 6.036 ± 2.107
0.0ValTrp: 0.0 ± 0.0
7.042ValTyr: 7.042 ± 3.334
0.0ValXaa: 0.0 ± 0.0
Trp
2.012TrpAla: 2.012 ± 1.54
0.0TrpCys: 0.0 ± 0.0
1.006TrpAsp: 1.006 ± 1.049
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
3.018TrpMet: 3.018 ± 1.82
2.012TrpAsn: 2.012 ± 2.384
0.0TrpPro: 0.0 ± 0.0
1.006TrpGln: 1.006 ± 0.77
0.0TrpArg: 0.0 ± 0.0
1.006TrpSer: 1.006 ± 1.077
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
4.024TrpTyr: 4.024 ± 2.101
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.024TyrAla: 4.024 ± 3.45
0.0TyrCys: 0.0 ± 0.0
2.012TyrAsp: 2.012 ± 1.172
2.012TyrGlu: 2.012 ± 1.725
3.018TyrPhe: 3.018 ± 0.855
2.012TyrGly: 2.012 ± 1.082
1.006TyrHis: 1.006 ± 0.77
2.012TyrIle: 2.012 ± 1.54
0.0TyrLys: 0.0 ± 0.0
4.024TyrLeu: 4.024 ± 2.208
2.012TyrMet: 2.012 ± 1.072
6.036TyrAsn: 6.036 ± 1.89
0.0TyrPro: 0.0 ± 0.0
1.006TyrGln: 1.006 ± 0.862
1.006TyrArg: 1.006 ± 0.862
1.006TyrSer: 1.006 ± 1.049
1.006TyrThr: 1.006 ± 0.77
8.048TyrVal: 8.048 ± 3.025
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (995 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski