Amino acid dipepetide frequency for Labilithrix luteola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.381AlaAla: 15.381 ± 0.094	2.184AlaCys: 2.184 ± 0.04	6.303AlaAsp: 6.303 ± 0.045	6.725AlaGlu: 6.725 ± 0.047	4.385AlaPhe: 4.385 ± 0.036	9.667AlaGly: 9.667 ± 0.059	2.504AlaHis: 2.504 ± 0.026	5.352AlaIle: 5.352 ± 0.044	4.763AlaLys: 4.763 ± 0.05	12.838AlaLeu: 12.838 ± 0.1	2.661AlaMet: 2.661 ± 0.029	3.057AlaAsn: 3.057 ± 0.032	7.634AlaPro: 7.634 ± 0.068	3.428AlaGln: 3.428 ± 0.033	10.257AlaArg: 10.257 ± 0.08	9.134AlaSer: 9.134 ± 0.059	7.39AlaThr: 7.39 ± 0.047	8.713AlaVal: 8.713 ± 0.053	1.708AlaTrp: 1.708 ± 0.023	2.299AlaTyr: 2.299 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	1.818CysAla: 1.818 ± 0.035	0.151CysCys: 0.151 ± 0.009	0.873CysAsp: 0.873 ± 0.023	0.755CysGlu: 0.755 ± 0.02	0.339CysPhe: 0.339 ± 0.009	1.69CysGly: 1.69 ± 0.055	0.29CysHis: 0.29 ± 0.014	0.409CysIle: 0.409 ± 0.013	0.394CysLys: 0.394 ± 0.012	0.773CysLeu: 0.773 ± 0.016	0.184CysMet: 0.184 ± 0.007	0.421CysAsn: 0.421 ± 0.015	0.806CysPro: 0.806 ± 0.023	0.32CysGln: 0.32 ± 0.01	0.674CysArg: 0.674 ± 0.015	1.022CysSer: 1.022 ± 0.023	0.893CysThr: 0.893 ± 0.025	0.975CysVal: 0.975 ± 0.019	0.263CysTrp: 0.263 ± 0.015	0.192CysTyr: 0.192 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	8.366AspAla: 8.366 ± 0.053	0.744AspCys: 0.744 ± 0.023	4.051AspAsp: 4.051 ± 0.042	3.857AspGlu: 3.857 ± 0.037	1.857AspPhe: 1.857 ± 0.025	6.27AspGly: 6.27 ± 0.062	1.127AspHis: 1.127 ± 0.019	1.951AspIle: 1.951 ± 0.023	1.684AspLys: 1.684 ± 0.026	5.35AspLeu: 5.35 ± 0.048	0.807AspMet: 0.807 ± 0.014	1.135AspAsn: 1.135 ± 0.02	3.793AspPro: 3.793 ± 0.033	1.28AspGln: 1.28 ± 0.02	3.945AspArg: 3.945 ± 0.04	2.62AspSer: 2.62 ± 0.027	2.585AspThr: 2.585 ± 0.031	5.632AspVal: 5.632 ± 0.044	0.652AspTrp: 0.652 ± 0.013	1.074AspTyr: 1.074 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	7.304GluAla: 7.304 ± 0.062	0.585GluCys: 0.585 ± 0.016	2.72GluAsp: 2.72 ± 0.031	3.337GluGlu: 3.337 ± 0.04	1.425GluPhe: 1.425 ± 0.022	4.516GluGly: 4.516 ± 0.042	1.383GluHis: 1.383 ± 0.022	2.543GluIle: 2.543 ± 0.027	2.106GluLys: 2.106 ± 0.03	6.384GluLeu: 6.384 ± 0.059	1.077GluMet: 1.077 ± 0.02	1.364GluAsn: 1.364 ± 0.018	3.153GluPro: 3.153 ± 0.031	1.921GluGln: 1.921 ± 0.025	5.621GluArg: 5.621 ± 0.058	3.178GluSer: 3.178 ± 0.033	3.153GluThr: 3.153 ± 0.034	4.237GluVal: 4.237 ± 0.037	0.639GluTrp: 0.639 ± 0.014	0.956GluTyr: 0.956 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	4.395PheAla: 4.395 ± 0.035	0.416PheCys: 0.416 ± 0.011	2.618PheAsp: 2.618 ± 0.028	2.223PheGlu: 2.223 ± 0.025	1.231PhePhe: 1.231 ± 0.02	3.492PheGly: 3.492 ± 0.035	0.687PheHis: 0.687 ± 0.013	0.939PheIle: 0.939 ± 0.018	0.751PheLys: 0.751 ± 0.018	2.762PheLeu: 2.762 ± 0.031	0.588PheMet: 0.588 ± 0.012	0.676PheAsn: 0.676 ± 0.015	1.506PhePro: 1.506 ± 0.021	0.799PheGln: 0.799 ± 0.016	2.142PheArg: 2.142 ± 0.027	1.905PheSer: 1.905 ± 0.025	1.905PheThr: 1.905 ± 0.022	3.403PheVal: 3.403 ± 0.033	0.419PheTrp: 0.419 ± 0.012	0.715PheTyr: 0.715 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	10.365GlyAla: 10.365 ± 0.073	1.394GlyCys: 1.394 ± 0.033	5.084GlyAsp: 5.084 ± 0.041	4.843GlyGlu: 4.843 ± 0.036	2.951GlyPhe: 2.951 ± 0.035	8.195GlyGly: 8.195 ± 0.085	1.762GlyHis: 1.762 ± 0.024	3.699GlyIle: 3.699 ± 0.038	3.543GlyLys: 3.543 ± 0.04	7.133GlyLeu: 7.133 ± 0.049	1.725GlyMet: 1.725 ± 0.024	2.32GlyAsn: 2.32 ± 0.033	4.137GlyPro: 4.137 ± 0.038	2.533GlyGln: 2.533 ± 0.032	5.792GlyArg: 5.792 ± 0.045	5.715GlySer: 5.715 ± 0.049	6.058GlyThr: 6.058 ± 0.053	6.494GlyVal: 6.494 ± 0.048	1.159GlyTrp: 1.159 ± 0.02	1.927GlyTyr: 1.927 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	2.781HisAla: 2.781 ± 0.03	0.259HisCys: 0.259 ± 0.01	1.307HisAsp: 1.307 ± 0.019	1.297HisGlu: 1.297 ± 0.02	0.738HisPhe: 0.738 ± 0.014	1.946HisGly: 1.946 ± 0.022	0.494HisHis: 0.494 ± 0.013	0.587HisIle: 0.587 ± 0.014	0.443HisLys: 0.443 ± 0.012	1.852HisLeu: 1.852 ± 0.024	0.362HisMet: 0.362 ± 0.01	0.327HisAsn: 0.327 ± 0.009	1.335HisPro: 1.335 ± 0.019	0.456HisGln: 0.456 ± 0.012	1.537HisArg: 1.537 ± 0.022	0.865HisSer: 0.865 ± 0.015	0.887HisThr: 0.887 ± 0.014	1.927HisVal: 1.927 ± 0.024	0.281HisTrp: 0.281 ± 0.008	0.479HisTyr: 0.479 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.641IleAla: 5.641 ± 0.045	0.352IleCys: 0.352 ± 0.01	2.926IleAsp: 2.926 ± 0.031	2.762IleGlu: 2.762 ± 0.03	1.087IlePhe: 1.087 ± 0.017	3.581IleGly: 3.581 ± 0.031	0.823IleHis: 0.823 ± 0.015	1.043IleIle: 1.043 ± 0.018	0.922IleLys: 0.922 ± 0.018	3.059IleLeu: 3.059 ± 0.033	0.47IleMet: 0.47 ± 0.012	0.745IleAsn: 0.745 ± 0.016	2.069IlePro: 2.069 ± 0.023	0.919IleGln: 0.919 ± 0.016	2.514IleArg: 2.514 ± 0.029	1.914IleSer: 1.914 ± 0.023	1.98IleThr: 1.98 ± 0.026	3.848IleVal: 3.848 ± 0.029	0.454IleTrp: 0.454 ± 0.016	0.718IleTyr: 0.718 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.741LysAla: 3.741 ± 0.041	0.419LysCys: 0.419 ± 0.019	1.89LysAsp: 1.89 ± 0.025	1.7LysGlu: 1.7 ± 0.025	0.826LysPhe: 0.826 ± 0.017	2.566LysGly: 2.566 ± 0.028	0.649LysHis: 0.649 ± 0.014	1.329LysIle: 1.329 ± 0.02	1.68LysLys: 1.68 ± 0.031	3.289LysLeu: 3.289 ± 0.029	0.745LysMet: 0.745 ± 0.014	1.044LysAsn: 1.044 ± 0.022	2.185LysPro: 2.185 ± 0.028	0.922LysGln: 0.922 ± 0.019	2.456LysArg: 2.456 ± 0.03	1.958LysSer: 1.958 ± 0.026	2.115LysThr: 2.115 ± 0.027	2.486LysVal: 2.486 ± 0.028	0.337LysTrp: 0.337 ± 0.009	0.601LysTyr: 0.601 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	13.184LeuAla: 13.184 ± 0.095	0.884LeuCys: 0.884 ± 0.016	5.965LeuAsp: 5.965 ± 0.047	5.969LeuGlu: 5.969 ± 0.061	3.077LeuPhe: 3.077 ± 0.032	8.518LeuGly: 8.518 ± 0.059	1.893LeuHis: 1.893 ± 0.026	2.348LeuIle: 2.348 ± 0.032	2.365LeuLys: 2.365 ± 0.028	8.483LeuLeu: 8.483 ± 0.067	1.364LeuMet: 1.364 ± 0.02	1.575LeuAsn: 1.575 ± 0.023	5.308LeuPro: 5.308 ± 0.038	2.111LeuGln: 2.111 ± 0.022	7.573LeuArg: 7.573 ± 0.062	5.722LeuSer: 5.722 ± 0.045	4.939LeuThr: 4.939 ± 0.037	8.684LeuVal: 8.684 ± 0.064	1.005LeuTrp: 1.005 ± 0.018	1.791LeuTyr: 1.791 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.197MetAla: 2.197 ± 0.025	0.174MetCys: 0.174 ± 0.007	0.786MetAsp: 0.786 ± 0.016	0.723MetGlu: 0.723 ± 0.017	0.58MetPhe: 0.58 ± 0.013	1.395MetGly: 1.395 ± 0.018	0.427MetHis: 0.427 ± 0.012	0.735MetIle: 0.735 ± 0.015	0.847MetLys: 0.847 ± 0.017	1.943MetLeu: 1.943 ± 0.022	0.428MetMet: 0.428 ± 0.011	0.618MetAsn: 0.618 ± 0.013	1.278MetPro: 1.278 ± 0.018	0.584MetGln: 0.584 ± 0.013	1.687MetArg: 1.687 ± 0.022	1.398MetSer: 1.398 ± 0.018	1.441MetThr: 1.441 ± 0.02	1.264MetVal: 1.264 ± 0.021	0.188MetTrp: 0.188 ± 0.007	0.286MetTyr: 0.286 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.241AsnAla: 3.241 ± 0.035	0.444AsnCys: 0.444 ± 0.023	1.65AsnAsp: 1.65 ± 0.025	1.374AsnGlu: 1.374 ± 0.021	0.723AsnPhe: 0.723 ± 0.015	2.684AsnGly: 2.684 ± 0.042	0.463AsnHis: 0.463 ± 0.013	0.79AsnIle: 0.79 ± 0.016	0.636AsnLys: 0.636 ± 0.015	2.009AsnLeu: 2.009 ± 0.026	0.368AsnMet: 0.368 ± 0.011	0.579AsnAsn: 0.579 ± 0.014	1.514AsnPro: 1.514 ± 0.022	0.605AsnGln: 0.605 ± 0.015	1.355AsnArg: 1.355 ± 0.018	1.064AsnSer: 1.064 ± 0.021	1.264AsnThr: 1.264 ± 0.023	2.353AsnVal: 2.353 ± 0.026	0.256AsnTrp: 0.256 ± 0.008	0.501AsnTyr: 0.501 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	6.928ProAla: 6.928 ± 0.054	0.564ProCys: 0.564 ± 0.014	3.399ProAsp: 3.399 ± 0.037	3.657ProGlu: 3.657 ± 0.038	1.985ProPhe: 1.985 ± 0.023	4.457ProGly: 4.457 ± 0.036	1.054ProHis: 1.054 ± 0.019	2.316ProIle: 2.316 ± 0.027	2.164ProLys: 2.164 ± 0.024	4.767ProLeu: 4.767 ± 0.034	1.32ProMet: 1.32 ± 0.019	1.776ProAsn: 1.776 ± 0.026	4.617ProPro: 4.617 ± 0.066	1.429ProGln: 1.429 ± 0.019	3.89ProArg: 3.89 ± 0.034	4.927ProSer: 4.927 ± 0.04	3.779ProThr: 3.779 ± 0.039	4.112ProVal: 4.112 ± 0.035	0.716ProTrp: 0.716 ± 0.017	1.08ProTyr: 1.08 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.135GlnAla: 3.135 ± 0.029	0.382GlnCys: 0.382 ± 0.014	1.178GlnAsp: 1.178 ± 0.019	1.213GlnGlu: 1.213 ± 0.021	0.817GlnPhe: 0.817 ± 0.015	2.082GlnGly: 2.082 ± 0.027	0.538GlnHis: 0.538 ± 0.01	1.218GlnIle: 1.218 ± 0.02	1.009GlnLys: 1.009 ± 0.02	2.634GlnLeu: 2.634 ± 0.033	0.564GlnMet: 0.564 ± 0.012	0.762GlnAsn: 0.762 ± 0.015	1.53GlnPro: 1.53 ± 0.024	0.868GlnGln: 0.868 ± 0.019	2.07GlnArg: 2.07 ± 0.024	1.514GlnSer: 1.514 ± 0.023	1.515GlnThr: 1.515 ± 0.024	1.926GlnVal: 1.926 ± 0.023	0.344GlnTrp: 0.344 ± 0.01	0.549GlnTyr: 0.549 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	9.916ArgAla: 9.916 ± 0.083	0.826ArgCys: 0.826 ± 0.017	4.085ArgAsp: 4.085 ± 0.036	4.669ArgGlu: 4.669 ± 0.048	2.823ArgPhe: 2.823 ± 0.028	5.423ArgGly: 5.423 ± 0.046	1.563ArgHis: 1.563 ± 0.02	3.513ArgIle: 3.513 ± 0.035	2.23ArgLys: 2.23 ± 0.028	7.252ArgLeu: 7.252 ± 0.069	1.824ArgMet: 1.824 ± 0.022	1.482ArgAsn: 1.482 ± 0.02	3.774ArgPro: 3.774 ± 0.039	1.757ArgGln: 1.757 ± 0.024	6.321ArgArg: 6.321 ± 0.067	4.688ArgSer: 4.688 ± 0.039	4.238ArgThr: 4.238 ± 0.037	5.96ArgVal: 5.96 ± 0.037	1.088ArgTrp: 1.088 ± 0.019	1.564ArgTyr: 1.564 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.632SerAla: 7.632 ± 0.052	0.998SerCys: 0.998 ± 0.021	3.615SerAsp: 3.615 ± 0.035	3.216SerGlu: 3.216 ± 0.031	2.465SerPhe: 2.465 ± 0.026	5.852SerGly: 5.852 ± 0.057	1.099SerHis: 1.099 ± 0.017	2.545SerIle: 2.545 ± 0.026	2.059SerLys: 2.059 ± 0.025	5.802SerLeu: 5.802 ± 0.039	1.321SerMet: 1.321 ± 0.021	1.726SerAsn: 1.726 ± 0.023	4.003SerPro: 4.003 ± 0.039	1.495SerGln: 1.495 ± 0.021	4.401SerArg: 4.401 ± 0.037	5.354SerSer: 5.354 ± 0.05	4.017SerThr: 4.017 ± 0.041	4.586SerVal: 4.586 ± 0.039	0.862SerTrp: 0.862 ± 0.016	1.24SerTyr: 1.24 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	6.359ThrAla: 6.359 ± 0.055	1.032ThrCys: 1.032 ± 0.03	3.175ThrAsp: 3.175 ± 0.038	2.71ThrGlu: 2.71 ± 0.028	2.295ThrPhe: 2.295 ± 0.026	5.02ThrGly: 5.02 ± 0.05	1.058ThrHis: 1.058 ± 0.017	2.569ThrIle: 2.569 ± 0.026	2.125ThrLys: 2.125 ± 0.024	5.595ThrLeu: 5.595 ± 0.04	1.164ThrMet: 1.164 ± 0.018	1.74ThrAsn: 1.74 ± 0.027	4.026ThrPro: 4.026 ± 0.04	1.442ThrGln: 1.442 ± 0.021	3.86ThrArg: 3.86 ± 0.037	4.38ThrSer: 4.38 ± 0.033	4.187ThrThr: 4.187 ± 0.043	4.436ThrVal: 4.436 ± 0.036	0.835ThrTrp: 0.835 ± 0.017	1.26ThrTyr: 1.26 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	10.273ValAla: 10.273 ± 0.064	0.978ValCys: 0.978 ± 0.024	5.163ValAsp: 5.163 ± 0.037	4.71ValGlu: 4.71 ± 0.041	2.721ValPhe: 2.721 ± 0.031	6.41ValGly: 6.41 ± 0.046	1.73ValHis: 1.73 ± 0.022	2.855ValIle: 2.855 ± 0.032	2.3ValLys: 2.3 ± 0.031	7.67ValLeu: 7.67 ± 0.058	1.378ValMet: 1.378 ± 0.019	1.731ValAsn: 1.731 ± 0.022	4.637ValPro: 4.637 ± 0.039	2.025ValGln: 2.025 ± 0.024	6.376ValArg: 6.376 ± 0.051	4.957ValSer: 4.957 ± 0.039	5.07ValThr: 5.07 ± 0.042	7.795ValVal: 7.795 ± 0.062	1.153ValTrp: 1.153 ± 0.027	1.531ValTyr: 1.531 ± 0.026	0.0ValXaa: 0.0 ± 0.0
Trp	1.317TrpAla: 1.317 ± 0.022	0.171TrpCys: 0.171 ± 0.007	0.677TrpAsp: 0.677 ± 0.016	0.584TrpGlu: 0.584 ± 0.013	0.459TrpPhe: 0.459 ± 0.013	1.247TrpGly: 1.247 ± 0.029	0.258TrpHis: 0.258 ± 0.009	0.574TrpIle: 0.574 ± 0.013	0.43TrpLys: 0.43 ± 0.01	1.402TrpLeu: 1.402 ± 0.023	0.305TrpMet: 0.305 ± 0.008	0.393TrpAsn: 0.393 ± 0.011	0.604TrpPro: 0.604 ± 0.014	0.396TrpGln: 0.396 ± 0.01	0.931TrpArg: 0.931 ± 0.016	0.931TrpSer: 0.931 ± 0.018	0.869TrpThr: 0.869 ± 0.017	0.86TrpVal: 0.86 ± 0.018	0.155TrpTrp: 0.155 ± 0.007	0.228TrpTyr: 0.228 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.408TyrAla: 2.408 ± 0.029	0.286TyrCys: 0.286 ± 0.01	1.317TyrAsp: 1.317 ± 0.019	1.274TyrGlu: 1.274 ± 0.019	0.787TyrPhe: 0.787 ± 0.017	1.818TyrGly: 1.818 ± 0.027	0.358TyrHis: 0.358 ± 0.01	0.511TyrIle: 0.511 ± 0.013	0.486TyrLys: 0.486 ± 0.013	1.762TyrLeu: 1.762 ± 0.023	0.325TyrMet: 0.325 ± 0.009	0.401TyrAsn: 0.401 ± 0.012	1.029TyrPro: 1.029 ± 0.018	0.555TyrGln: 0.555 ± 0.012	1.597TyrArg: 1.597 ± 0.024	1.044TyrSer: 1.044 ± 0.019	0.985TyrThr: 0.985 ± 0.018	1.77TyrVal: 1.77 ± 0.025	0.279TyrTrp: 0.279 ± 0.009	0.473TyrTyr: 0.473 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11481 proteins (3621879 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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