Amino acid dipepetide frequency for Inachis io cypovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.519AlaAla: 3.519 ± 0.458
0.947AlaCys: 0.947 ± 0.527
2.572AlaAsp: 2.572 ± 0.484
2.436AlaGlu: 2.436 ± 0.422
3.519AlaPhe: 3.519 ± 0.925
2.572AlaGly: 2.572 ± 0.381
1.083AlaHis: 1.083 ± 0.195
4.602AlaIle: 4.602 ± 0.579
3.113AlaLys: 3.113 ± 0.856
5.414AlaLeu: 5.414 ± 0.685
2.301AlaMet: 2.301 ± 0.781
5.008AlaAsn: 5.008 ± 0.801
2.166AlaPro: 2.166 ± 0.654
2.978AlaGln: 2.978 ± 0.441
2.436AlaArg: 2.436 ± 0.532
3.655AlaSer: 3.655 ± 0.513
2.842AlaThr: 2.842 ± 0.394
3.925AlaVal: 3.925 ± 0.654
0.135AlaTrp: 0.135 ± 0.11
4.331AlaTyr: 4.331 ± 0.66
0.0AlaXaa: 0.0 ± 0.0
Cys
0.406CysAla: 0.406 ± 0.212
0.135CysCys: 0.135 ± 0.124
0.677CysAsp: 0.677 ± 0.312
0.541CysGlu: 0.541 ± 0.32
0.271CysPhe: 0.271 ± 0.172
0.677CysGly: 0.677 ± 0.286
0.271CysHis: 0.271 ± 0.165
0.406CysIle: 0.406 ± 0.237
0.406CysLys: 0.406 ± 0.257
1.489CysLeu: 1.489 ± 0.301
0.271CysMet: 0.271 ± 0.18
0.271CysAsn: 0.271 ± 0.126
0.271CysPro: 0.271 ± 0.215
0.812CysGln: 0.812 ± 0.244
1.083CysArg: 1.083 ± 0.326
1.218CysSer: 1.218 ± 0.301
0.812CysThr: 0.812 ± 0.349
0.677CysVal: 0.677 ± 0.253
0.406CysTrp: 0.406 ± 0.184
0.541CysTyr: 0.541 ± 0.243
0.0CysXaa: 0.0 ± 0.0
Asp
2.842AspAla: 2.842 ± 0.545
0.406AspCys: 0.406 ± 0.194
4.467AspAsp: 4.467 ± 0.719
4.737AspGlu: 4.737 ± 1.073
2.978AspPhe: 2.978 ± 0.505
2.842AspGly: 2.842 ± 0.471
1.083AspHis: 1.083 ± 0.18
6.497AspIle: 6.497 ± 0.91
4.602AspLys: 4.602 ± 0.877
5.685AspLeu: 5.685 ± 0.709
1.083AspMet: 1.083 ± 0.217
2.572AspAsn: 2.572 ± 0.518
2.436AspPro: 2.436 ± 0.441
1.489AspGln: 1.489 ± 0.333
2.572AspArg: 2.572 ± 0.319
2.978AspSer: 2.978 ± 0.561
3.249AspThr: 3.249 ± 0.672
4.467AspVal: 4.467 ± 0.362
0.812AspTrp: 0.812 ± 0.425
2.301AspTyr: 2.301 ± 0.385
0.0AspXaa: 0.0 ± 0.0
Glu
4.467GluAla: 4.467 ± 0.898
0.271GluCys: 0.271 ± 0.173
3.655GluAsp: 3.655 ± 0.527
2.842GluGlu: 2.842 ± 0.32
2.166GluPhe: 2.166 ± 0.491
2.842GluGly: 2.842 ± 0.521
1.218GluHis: 1.218 ± 0.286
2.03GluIle: 2.03 ± 0.471
2.301GluLys: 2.301 ± 0.624
6.632GluLeu: 6.632 ± 0.82
1.489GluMet: 1.489 ± 0.561
2.707GluAsn: 2.707 ± 0.52
2.03GluPro: 2.03 ± 0.547
1.624GluGln: 1.624 ± 0.267
2.707GluArg: 2.707 ± 0.693
4.873GluSer: 4.873 ± 0.692
3.113GluThr: 3.113 ± 0.636
3.249GluVal: 3.249 ± 0.928
0.0GluTrp: 0.0 ± 0.0
2.842GluTyr: 2.842 ± 0.458
0.0GluXaa: 0.0 ± 0.0
Phe
1.354PheAla: 1.354 ± 0.564
0.406PheCys: 0.406 ± 0.191
2.436PheAsp: 2.436 ± 0.444
3.249PheGlu: 3.249 ± 0.453
1.624PhePhe: 1.624 ± 0.558
3.249PheGly: 3.249 ± 0.587
1.354PheHis: 1.354 ± 0.387
4.467PheIle: 4.467 ± 0.669
2.301PheLys: 2.301 ± 0.534
3.384PheLeu: 3.384 ± 0.966
1.354PheMet: 1.354 ± 0.285
4.331PheAsn: 4.331 ± 1.128
1.624PhePro: 1.624 ± 0.503
1.218PheGln: 1.218 ± 0.38
2.03PheArg: 2.03 ± 0.463
3.249PheSer: 3.249 ± 0.737
4.737PheThr: 4.737 ± 0.624
2.166PheVal: 2.166 ± 0.399
0.135PheTrp: 0.135 ± 0.124
1.624PheTyr: 1.624 ± 0.265
0.0PheXaa: 0.0 ± 0.0
Gly
2.842GlyAla: 2.842 ± 0.385
0.541GlyCys: 0.541 ± 0.307
3.519GlyAsp: 3.519 ± 0.605
3.925GlyGlu: 3.925 ± 0.71
2.301GlyPhe: 2.301 ± 0.393
2.978GlyGly: 2.978 ± 0.517
0.812GlyHis: 0.812 ± 0.406
4.061GlyIle: 4.061 ± 0.632
2.436GlyLys: 2.436 ± 0.733
3.249GlyLeu: 3.249 ± 0.703
1.354GlyMet: 1.354 ± 0.325
2.572GlyAsn: 2.572 ± 0.483
1.76GlyPro: 1.76 ± 0.433
2.166GlyGln: 2.166 ± 0.456
3.384GlyArg: 3.384 ± 0.449
4.331GlySer: 4.331 ± 0.912
2.03GlyThr: 2.03 ± 0.303
3.925GlyVal: 3.925 ± 0.757
0.541GlyTrp: 0.541 ± 0.207
1.083GlyTyr: 1.083 ± 0.358
0.0GlyXaa: 0.0 ± 0.0
His
1.895HisAla: 1.895 ± 0.355
0.541HisCys: 0.541 ± 0.242
1.624HisAsp: 1.624 ± 0.501
0.812HisGlu: 0.812 ± 0.321
0.812HisPhe: 0.812 ± 0.26
1.489HisGly: 1.489 ± 0.378
0.677HisHis: 0.677 ± 0.243
2.03HisIle: 2.03 ± 0.563
0.812HisLys: 0.812 ± 0.284
2.436HisLeu: 2.436 ± 0.645
1.083HisMet: 1.083 ± 0.309
1.489HisAsn: 1.489 ± 0.548
0.677HisPro: 0.677 ± 0.196
0.271HisGln: 0.271 ± 0.189
0.812HisArg: 0.812 ± 0.284
1.895HisSer: 1.895 ± 0.393
2.301HisThr: 2.301 ± 0.571
1.218HisVal: 1.218 ± 0.292
0.135HisTrp: 0.135 ± 0.124
1.76HisTyr: 1.76 ± 0.445
0.0HisXaa: 0.0 ± 0.0
Ile
4.737IleAla: 4.737 ± 0.5
1.083IleCys: 1.083 ± 0.3
4.873IleAsp: 4.873 ± 0.687
3.519IleGlu: 3.519 ± 0.772
4.331IlePhe: 4.331 ± 0.76
3.655IleGly: 3.655 ± 0.524
1.489IleHis: 1.489 ± 0.494
7.986IleIle: 7.986 ± 0.856
3.519IleLys: 3.519 ± 0.615
4.602IleLeu: 4.602 ± 0.723
1.76IleMet: 1.76 ± 0.293
5.956IleAsn: 5.956 ± 0.483
4.737IlePro: 4.737 ± 0.762
2.572IleGln: 2.572 ± 0.548
3.249IleArg: 3.249 ± 0.601
4.873IleSer: 4.873 ± 0.768
5.143IleThr: 5.143 ± 0.518
3.519IleVal: 3.519 ± 0.504
0.406IleTrp: 0.406 ± 0.331
2.842IleTyr: 2.842 ± 0.844
0.0IleXaa: 0.0 ± 0.0
Lys
2.301LysAla: 2.301 ± 0.635
0.406LysCys: 0.406 ± 0.228
3.249LysAsp: 3.249 ± 0.576
2.436LysGlu: 2.436 ± 0.761
2.03LysPhe: 2.03 ± 0.391
2.166LysGly: 2.166 ± 0.691
2.166LysHis: 2.166 ± 0.507
3.79LysIle: 3.79 ± 0.762
3.249LysLys: 3.249 ± 0.965
4.061LysLeu: 4.061 ± 0.79
1.354LysMet: 1.354 ± 0.292
2.166LysAsn: 2.166 ± 0.607
2.572LysPro: 2.572 ± 0.563
1.895LysGln: 1.895 ± 0.56
2.166LysArg: 2.166 ± 0.359
3.113LysSer: 3.113 ± 0.677
4.061LysThr: 4.061 ± 0.969
2.436LysVal: 2.436 ± 0.629
0.812LysTrp: 0.812 ± 0.364
2.707LysTyr: 2.707 ± 0.491
0.0LysXaa: 0.0 ± 0.0
Leu
5.685LeuAla: 5.685 ± 0.878
1.895LeuCys: 1.895 ± 0.432
4.602LeuAsp: 4.602 ± 0.909
5.414LeuGlu: 5.414 ± 0.551
5.008LeuPhe: 5.008 ± 1.001
3.249LeuGly: 3.249 ± 0.999
2.03LeuHis: 2.03 ± 0.661
5.685LeuIle: 5.685 ± 0.768
4.331LeuLys: 4.331 ± 0.952
7.309LeuLeu: 7.309 ± 1.108
3.249LeuMet: 3.249 ± 0.739
4.061LeuAsn: 4.061 ± 0.873
5.008LeuPro: 5.008 ± 0.754
3.79LeuGln: 3.79 ± 0.572
6.362LeuArg: 6.362 ± 0.999
7.038LeuSer: 7.038 ± 0.855
6.632LeuThr: 6.632 ± 0.798
5.008LeuVal: 5.008 ± 0.828
0.135LeuTrp: 0.135 ± 0.11
2.842LeuTyr: 2.842 ± 0.503
0.0LeuXaa: 0.0 ± 0.0
Met
2.166MetAla: 2.166 ± 0.361
0.135MetCys: 0.135 ± 0.13
1.489MetAsp: 1.489 ± 0.527
1.624MetGlu: 1.624 ± 0.569
1.218MetPhe: 1.218 ± 0.375
0.947MetGly: 0.947 ± 0.26
0.947MetHis: 0.947 ± 0.265
1.76MetIle: 1.76 ± 0.518
1.489MetLys: 1.489 ± 0.327
3.249MetLeu: 3.249 ± 0.636
0.677MetMet: 0.677 ± 0.241
1.76MetAsn: 1.76 ± 0.533
0.812MetPro: 0.812 ± 0.334
0.677MetGln: 0.677 ± 0.369
1.354MetArg: 1.354 ± 0.836
2.03MetSer: 2.03 ± 0.563
2.03MetThr: 2.03 ± 0.623
1.083MetVal: 1.083 ± 0.358
0.135MetTrp: 0.135 ± 0.124
1.083MetTyr: 1.083 ± 0.344
0.0MetXaa: 0.0 ± 0.0
Asn
4.467AsnAla: 4.467 ± 0.541
0.135AsnCys: 0.135 ± 0.119
4.331AsnAsp: 4.331 ± 0.748
3.925AsnGlu: 3.925 ± 0.466
2.166AsnPhe: 2.166 ± 0.558
3.79AsnGly: 3.79 ± 0.522
2.301AsnHis: 2.301 ± 0.38
4.331AsnIle: 4.331 ± 0.802
2.572AsnLys: 2.572 ± 0.804
5.143AsnLeu: 5.143 ± 0.985
1.76AsnMet: 1.76 ± 0.411
4.331AsnAsn: 4.331 ± 0.782
3.249AsnPro: 3.249 ± 0.711
1.76AsnGln: 1.76 ± 0.365
3.925AsnArg: 3.925 ± 0.649
3.384AsnSer: 3.384 ± 0.776
4.196AsnThr: 4.196 ± 1.014
3.925AsnVal: 3.925 ± 0.625
0.406AsnTrp: 0.406 ± 0.172
3.925AsnTyr: 3.925 ± 0.453
0.0AsnXaa: 0.0 ± 0.0
Pro
2.03ProAla: 2.03 ± 0.448
0.406ProCys: 0.406 ± 0.341
2.842ProAsp: 2.842 ± 0.564
1.489ProGlu: 1.489 ± 0.429
2.436ProPhe: 2.436 ± 0.543
2.03ProGly: 2.03 ± 0.649
0.812ProHis: 0.812 ± 0.344
2.978ProIle: 2.978 ± 0.577
1.76ProLys: 1.76 ± 0.472
4.331ProLeu: 4.331 ± 0.483
0.677ProMet: 0.677 ± 0.236
2.842ProAsn: 2.842 ± 0.554
2.166ProPro: 2.166 ± 0.342
1.083ProGln: 1.083 ± 0.446
2.572ProArg: 2.572 ± 0.456
4.331ProSer: 4.331 ± 0.66
3.384ProThr: 3.384 ± 0.534
3.655ProVal: 3.655 ± 0.747
0.406ProTrp: 0.406 ± 0.219
2.301ProTyr: 2.301 ± 0.78
0.0ProXaa: 0.0 ± 0.0
Gln
1.895GlnAla: 1.895 ± 0.396
0.271GlnCys: 0.271 ± 0.192
1.624GlnAsp: 1.624 ± 0.785
1.489GlnGlu: 1.489 ± 0.332
1.624GlnPhe: 1.624 ± 0.315
0.947GlnGly: 0.947 ± 0.463
0.677GlnHis: 0.677 ± 0.371
2.978GlnIle: 2.978 ± 0.642
1.895GlnLys: 1.895 ± 0.615
3.113GlnLeu: 3.113 ± 0.736
0.947GlnMet: 0.947 ± 0.344
2.842GlnAsn: 2.842 ± 0.466
1.083GlnPro: 1.083 ± 0.279
2.166GlnGln: 2.166 ± 0.427
1.489GlnArg: 1.489 ± 0.282
2.03GlnSer: 2.03 ± 0.683
2.707GlnThr: 2.707 ± 0.612
2.572GlnVal: 2.572 ± 0.536
0.406GlnTrp: 0.406 ± 0.261
1.76GlnTyr: 1.76 ± 0.516
0.0GlnXaa: 0.0 ± 0.0
Arg
2.301ArgAla: 2.301 ± 0.522
0.812ArgCys: 0.812 ± 0.379
3.113ArgAsp: 3.113 ± 0.551
3.113ArgGlu: 3.113 ± 0.723
2.03ArgPhe: 2.03 ± 0.514
2.166ArgGly: 2.166 ± 0.34
0.812ArgHis: 0.812 ± 0.302
4.061ArgIle: 4.061 ± 0.67
2.301ArgLys: 2.301 ± 0.545
7.038ArgLeu: 7.038 ± 0.828
1.218ArgMet: 1.218 ± 0.402
3.384ArgAsn: 3.384 ± 0.64
2.572ArgPro: 2.572 ± 0.529
1.895ArgGln: 1.895 ± 0.562
2.978ArgArg: 2.978 ± 0.647
2.978ArgSer: 2.978 ± 0.556
3.384ArgThr: 3.384 ± 0.58
3.249ArgVal: 3.249 ± 0.352
0.271ArgTrp: 0.271 ± 0.165
2.978ArgTyr: 2.978 ± 0.817
0.0ArgXaa: 0.0 ± 0.0
Ser
3.249SerAla: 3.249 ± 0.995
1.354SerCys: 1.354 ± 0.327
4.331SerAsp: 4.331 ± 0.889
4.061SerGlu: 4.061 ± 0.674
3.79SerPhe: 3.79 ± 0.475
3.79SerGly: 3.79 ± 0.639
2.03SerHis: 2.03 ± 0.294
5.55SerIle: 5.55 ± 0.805
4.061SerLys: 4.061 ± 0.591
6.362SerLeu: 6.362 ± 0.809
2.03SerMet: 2.03 ± 0.44
4.873SerAsn: 4.873 ± 0.723
2.301SerPro: 2.301 ± 0.465
2.301SerGln: 2.301 ± 0.399
2.842SerArg: 2.842 ± 0.379
6.091SerSer: 6.091 ± 1.424
6.632SerThr: 6.632 ± 0.357
4.873SerVal: 4.873 ± 0.699
0.541SerTrp: 0.541 ± 0.241
3.925SerTyr: 3.925 ± 0.772
0.0SerXaa: 0.0 ± 0.0
Thr
5.279ThrAla: 5.279 ± 0.852
0.677ThrCys: 0.677 ± 0.334
3.519ThrAsp: 3.519 ± 0.78
2.436ThrGlu: 2.436 ± 0.374
3.519ThrPhe: 3.519 ± 0.463
3.925ThrGly: 3.925 ± 0.371
1.895ThrHis: 1.895 ± 0.353
4.467ThrIle: 4.467 ± 0.88
3.113ThrLys: 3.113 ± 0.77
6.497ThrLeu: 6.497 ± 1.323
1.489ThrMet: 1.489 ± 0.421
5.685ThrAsn: 5.685 ± 1.08
2.978ThrPro: 2.978 ± 0.697
2.436ThrGln: 2.436 ± 0.538
3.655ThrArg: 3.655 ± 0.62
7.038ThrSer: 7.038 ± 0.77
4.602ThrThr: 4.602 ± 0.967
4.331ThrVal: 4.331 ± 0.568
0.541ThrTrp: 0.541 ± 0.342
2.572ThrTyr: 2.572 ± 0.661
0.0ThrXaa: 0.0 ± 0.0
Val
3.519ValAla: 3.519 ± 1.071
0.812ValCys: 0.812 ± 0.356
3.79ValAsp: 3.79 ± 0.627
3.249ValGlu: 3.249 ± 0.543
2.436ValPhe: 2.436 ± 0.412
3.384ValGly: 3.384 ± 0.448
1.895ValHis: 1.895 ± 0.449
4.061ValIle: 4.061 ± 0.59
2.436ValLys: 2.436 ± 0.741
4.602ValLeu: 4.602 ± 0.636
1.489ValMet: 1.489 ± 0.531
3.113ValAsn: 3.113 ± 0.67
3.655ValPro: 3.655 ± 0.563
2.166ValGln: 2.166 ± 0.456
3.79ValArg: 3.79 ± 0.715
5.956ValSer: 5.956 ± 0.627
3.384ValThr: 3.384 ± 0.567
2.978ValVal: 2.978 ± 0.488
0.947ValTrp: 0.947 ± 0.418
2.03ValTyr: 2.03 ± 0.565
0.0ValXaa: 0.0 ± 0.0
Trp
0.271TrpAla: 0.271 ± 0.151
0.0TrpCys: 0.0 ± 0.0
0.406TrpAsp: 0.406 ± 0.242
0.271TrpGlu: 0.271 ± 0.151
0.406TrpPhe: 0.406 ± 0.284
0.271TrpGly: 0.271 ± 0.151
0.271TrpHis: 0.271 ± 0.174
0.812TrpIle: 0.812 ± 0.126
0.271TrpLys: 0.271 ± 0.166
0.677TrpLeu: 0.677 ± 0.298
0.135TrpMet: 0.135 ± 0.124
0.271TrpAsn: 0.271 ± 0.171
0.135TrpPro: 0.135 ± 0.11
0.271TrpGln: 0.271 ± 0.182
0.947TrpArg: 0.947 ± 0.339
0.135TrpSer: 0.135 ± 0.11
0.677TrpThr: 0.677 ± 0.251
0.271TrpVal: 0.271 ± 0.151
0.0TrpTrp: 0.0 ± 0.0
0.677TrpTyr: 0.677 ± 0.328
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.467TyrAla: 4.467 ± 0.858
0.406TyrCys: 0.406 ± 0.294
2.978TyrAsp: 2.978 ± 0.914
1.489TyrGlu: 1.489 ± 0.431
1.624TyrPhe: 1.624 ± 0.348
2.842TyrGly: 2.842 ± 0.576
0.947TyrHis: 0.947 ± 0.391
2.301TyrIle: 2.301 ± 0.454
2.166TyrLys: 2.166 ± 0.357
4.061TyrLeu: 4.061 ± 0.84
0.812TyrMet: 0.812 ± 0.3
3.79TyrAsn: 3.79 ± 0.665
2.301TyrPro: 2.301 ± 0.691
0.947TyrGln: 0.947 ± 0.328
2.301TyrArg: 2.301 ± 0.575
3.79TyrSer: 3.79 ± 0.66
4.737TyrThr: 4.737 ± 0.585
2.166TyrVal: 2.166 ± 0.502
0.0TyrTrp: 0.0 ± 0.0
2.436TyrTyr: 2.436 ± 0.828
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (7389 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski