Amino acid dipepetide frequency for Lake Sarah-associated circular virus-36

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.405AlaAla: 5.405 ± 1.229
0.0AlaCys: 0.0 ± 0.0
5.405AlaAsp: 5.405 ± 1.229
1.802AlaGlu: 1.802 ± 1.229
1.802AlaPhe: 1.802 ± 1.229
9.009AlaGly: 9.009 ± 1.229
3.604AlaHis: 3.604 ± 2.458
0.0AlaIle: 0.0 ± 0.0
0.0AlaLys: 0.0 ± 0.0
7.207AlaLeu: 7.207 ± 2.458
1.802AlaMet: 1.802 ± 1.229
1.802AlaAsn: 1.802 ± 1.229
3.604AlaPro: 3.604 ± 2.458
0.0AlaGln: 0.0 ± 0.0
3.604AlaArg: 3.604 ± 0.0
5.405AlaSer: 5.405 ± 1.229
3.604AlaThr: 3.604 ± 0.0
9.009AlaVal: 9.009 ± 1.229
0.0AlaTrp: 0.0 ± 0.0
3.604AlaTyr: 3.604 ± 2.458
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.802CysPhe: 1.802 ± 1.229
0.0CysGly: 0.0 ± 0.0
1.802CysHis: 1.802 ± 1.229
0.0CysIle: 0.0 ± 0.0
1.802CysLys: 1.802 ± 1.229
1.802CysLeu: 1.802 ± 1.229
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.604CysSer: 3.604 ± 2.458
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.604AspAla: 3.604 ± 0.0
0.0AspCys: 0.0 ± 0.0
3.604AspAsp: 3.604 ± 2.458
0.0AspGlu: 0.0 ± 0.0
5.405AspPhe: 5.405 ± 1.229
7.207AspGly: 7.207 ± 2.458
1.802AspHis: 1.802 ± 1.229
3.604AspIle: 3.604 ± 0.0
0.0AspLys: 0.0 ± 0.0
3.604AspLeu: 3.604 ± 0.0
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
5.405AspPro: 5.405 ± 3.686
0.0AspGln: 0.0 ± 0.0
5.405AspArg: 5.405 ± 3.686
3.604AspSer: 3.604 ± 0.0
1.802AspThr: 1.802 ± 1.229
5.405AspVal: 5.405 ± 1.229
1.802AspTrp: 1.802 ± 1.229
1.802AspTyr: 1.802 ± 1.229
0.0AspXaa: 0.0 ± 0.0
Glu
3.604GluAla: 3.604 ± 0.0
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
3.604GluGlu: 3.604 ± 0.0
1.802GluPhe: 1.802 ± 1.229
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
3.604GluIle: 3.604 ± 2.458
7.207GluLys: 7.207 ± 0.0
3.604GluLeu: 3.604 ± 2.458
1.802GluMet: 1.802 ± 1.229
1.802GluAsn: 1.802 ± 1.229
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
1.802GluArg: 1.802 ± 1.229
1.802GluSer: 1.802 ± 1.229
3.604GluThr: 3.604 ± 2.458
3.604GluVal: 3.604 ± 2.458
0.0GluTrp: 0.0 ± 0.0
3.604GluTyr: 3.604 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
7.207PheAla: 7.207 ± 2.458
0.0PheCys: 0.0 ± 0.0
1.802PheAsp: 1.802 ± 1.229
1.802PheGlu: 1.802 ± 1.229
0.0PhePhe: 0.0 ± 0.0
5.405PheGly: 5.405 ± 3.686
3.604PheHis: 3.604 ± 0.0
3.604PheIle: 3.604 ± 0.0
1.802PheLys: 1.802 ± 1.229
1.802PheLeu: 1.802 ± 1.229
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.802PhePro: 1.802 ± 1.229
0.0PheGln: 0.0 ± 0.0
1.802PheArg: 1.802 ± 1.229
7.207PheSer: 7.207 ± 2.458
1.802PheThr: 1.802 ± 1.229
1.802PheVal: 1.802 ± 1.229
1.802PheTrp: 1.802 ± 1.229
1.802PheTyr: 1.802 ± 1.229
0.0PheXaa: 0.0 ± 0.0
Gly
5.405GlyAla: 5.405 ± 1.229
0.0GlyCys: 0.0 ± 0.0
10.811GlyAsp: 10.811 ± 2.458
5.405GlyGlu: 5.405 ± 3.686
1.802GlyPhe: 1.802 ± 1.229
10.811GlyGly: 10.811 ± 2.458
1.802GlyHis: 1.802 ± 1.229
1.802GlyIle: 1.802 ± 1.229
5.405GlyLys: 5.405 ± 1.229
3.604GlyLeu: 3.604 ± 2.458
5.405GlyMet: 5.405 ± 1.229
5.405GlyAsn: 5.405 ± 3.686
1.802GlyPro: 1.802 ± 1.229
0.0GlyGln: 0.0 ± 0.0
7.207GlyArg: 7.207 ± 0.0
1.802GlySer: 1.802 ± 1.229
5.405GlyThr: 5.405 ± 1.229
3.604GlyVal: 3.604 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
1.802GlyTyr: 1.802 ± 1.229
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
3.604HisGlu: 3.604 ± 2.458
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
3.604HisIle: 3.604 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.604HisLeu: 3.604 ± 2.458
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.802HisPro: 1.802 ± 1.229
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.802HisSer: 1.802 ± 1.229
3.604HisThr: 3.604 ± 2.458
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
5.405IleAsp: 5.405 ± 1.229
1.802IleGlu: 1.802 ± 1.229
1.802IlePhe: 1.802 ± 1.229
1.802IleGly: 1.802 ± 1.229
0.0IleHis: 0.0 ± 0.0
9.009IleIle: 9.009 ± 1.229
5.405IleLys: 5.405 ± 1.229
3.604IleLeu: 3.604 ± 2.458
1.802IleMet: 1.802 ± 1.229
3.604IleAsn: 3.604 ± 0.0
1.802IlePro: 1.802 ± 1.229
0.0IleGln: 0.0 ± 0.0
5.405IleArg: 5.405 ± 1.229
1.802IleSer: 1.802 ± 1.229
3.604IleThr: 3.604 ± 2.458
1.802IleVal: 1.802 ± 1.229
1.802IleTrp: 1.802 ± 1.229
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.405LysAla: 5.405 ± 1.229
1.802LysCys: 1.802 ± 1.229
7.207LysAsp: 7.207 ± 4.915
3.604LysGlu: 3.604 ± 0.0
0.0LysPhe: 0.0 ± 0.0
3.604LysGly: 3.604 ± 0.0
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
9.009LysLys: 9.009 ± 1.229
0.0LysLeu: 0.0 ± 0.0
1.802LysMet: 1.802 ± 1.229
1.802LysAsn: 1.802 ± 1.229
3.604LysPro: 3.604 ± 2.458
1.802LysGln: 1.802 ± 1.229
5.405LysArg: 5.405 ± 3.686
5.405LysSer: 5.405 ± 3.686
0.0LysThr: 0.0 ± 0.0
3.604LysVal: 3.604 ± 0.0
1.802LysTrp: 1.802 ± 1.229
1.802LysTyr: 1.802 ± 1.229
0.0LysXaa: 0.0 ± 0.0
Leu
7.207LeuAla: 7.207 ± 2.458
0.0LeuCys: 0.0 ± 0.0
3.604LeuAsp: 3.604 ± 2.458
5.405LeuGlu: 5.405 ± 1.229
0.0LeuPhe: 0.0 ± 0.0
3.604LeuGly: 3.604 ± 2.458
0.0LeuHis: 0.0 ± 0.0
1.802LeuIle: 1.802 ± 1.229
3.604LeuLys: 3.604 ± 2.458
9.009LeuLeu: 9.009 ± 1.229
3.604LeuMet: 3.604 ± 0.0
3.604LeuAsn: 3.604 ± 0.0
3.604LeuPro: 3.604 ± 2.458
5.405LeuGln: 5.405 ± 1.229
7.207LeuArg: 7.207 ± 4.915
5.405LeuSer: 5.405 ± 3.686
1.802LeuThr: 1.802 ± 1.229
5.405LeuVal: 5.405 ± 1.229
1.802LeuTrp: 1.802 ± 1.229
3.604LeuTyr: 3.604 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
5.405MetAla: 5.405 ± 3.686
0.0MetCys: 0.0 ± 0.0
1.802MetAsp: 1.802 ± 1.229
1.802MetGlu: 1.802 ± 1.229
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
5.405MetIle: 5.405 ± 1.229
1.802MetLys: 1.802 ± 1.229
3.604MetLeu: 3.604 ± 0.0
1.802MetMet: 1.802 ± 1.229
0.0MetAsn: 0.0 ± 0.0
1.802MetPro: 1.802 ± 1.229
3.604MetGln: 3.604 ± 2.458
1.802MetArg: 1.802 ± 1.229
1.802MetSer: 1.802 ± 1.229
1.802MetThr: 1.802 ± 1.229
3.604MetVal: 3.604 ± 2.458
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.802AsnGlu: 1.802 ± 1.229
5.405AsnPhe: 5.405 ± 3.686
1.802AsnGly: 1.802 ± 1.229
3.604AsnHis: 3.604 ± 0.0
1.802AsnIle: 1.802 ± 1.229
0.0AsnLys: 0.0 ± 0.0
3.604AsnLeu: 3.604 ± 2.458
0.0AsnMet: 0.0 ± 0.0
1.802AsnAsn: 1.802 ± 1.229
5.405AsnPro: 5.405 ± 1.229
5.405AsnGln: 5.405 ± 3.686
1.802AsnArg: 1.802 ± 1.229
0.0AsnSer: 0.0 ± 0.0
5.405AsnThr: 5.405 ± 3.686
5.405AsnVal: 5.405 ± 1.229
1.802AsnTrp: 1.802 ± 1.229
3.604AsnTyr: 3.604 ± 2.458
0.0AsnXaa: 0.0 ± 0.0
Pro
3.604ProAla: 3.604 ± 2.458
1.802ProCys: 1.802 ± 1.229
1.802ProAsp: 1.802 ± 1.229
1.802ProGlu: 1.802 ± 1.229
1.802ProPhe: 1.802 ± 1.229
9.009ProGly: 9.009 ± 1.229
1.802ProHis: 1.802 ± 1.229
0.0ProIle: 0.0 ± 0.0
3.604ProLys: 3.604 ± 0.0
5.405ProLeu: 5.405 ± 1.229
0.0ProMet: 0.0 ± 0.0
1.802ProAsn: 1.802 ± 1.229
0.0ProPro: 0.0 ± 0.0
1.802ProGln: 1.802 ± 1.229
1.802ProArg: 1.802 ± 1.229
1.802ProSer: 1.802 ± 1.229
9.009ProThr: 9.009 ± 1.229
3.604ProVal: 3.604 ± 2.458
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.802GlnAla: 1.802 ± 1.229
0.0GlnCys: 0.0 ± 0.0
1.802GlnAsp: 1.802 ± 1.229
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
3.604GlnGly: 3.604 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
3.604GlnLeu: 3.604 ± 0.0
0.0GlnMet: 0.0 ± 0.0
3.604GlnAsn: 3.604 ± 2.458
7.207GlnPro: 7.207 ± 2.458
0.0GlnGln: 0.0 ± 0.0
1.802GlnArg: 1.802 ± 1.229
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
0.0GlnVal: 0.0 ± 0.0
1.802GlnTrp: 1.802 ± 1.229
1.802GlnTyr: 1.802 ± 1.229
0.0GlnXaa: 0.0 ± 0.0
Arg
1.802ArgAla: 1.802 ± 1.229
1.802ArgCys: 1.802 ± 1.229
0.0ArgAsp: 0.0 ± 0.0
1.802ArgGlu: 1.802 ± 1.229
7.207ArgPhe: 7.207 ± 2.458
1.802ArgGly: 1.802 ± 1.229
0.0ArgHis: 0.0 ± 0.0
0.0ArgIle: 0.0 ± 0.0
5.405ArgLys: 5.405 ± 1.229
3.604ArgLeu: 3.604 ± 2.458
7.207ArgMet: 7.207 ± 2.458
5.405ArgAsn: 5.405 ± 1.229
1.802ArgPro: 1.802 ± 1.229
1.802ArgGln: 1.802 ± 1.229
9.009ArgArg: 9.009 ± 3.686
9.009ArgSer: 9.009 ± 1.229
5.405ArgThr: 5.405 ± 1.229
5.405ArgVal: 5.405 ± 1.229
1.802ArgTrp: 1.802 ± 1.229
7.207ArgTyr: 7.207 ± 2.458
0.0ArgXaa: 0.0 ± 0.0
Ser
3.604SerAla: 3.604 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.604SerAsp: 3.604 ± 0.0
3.604SerGlu: 3.604 ± 0.0
7.207SerPhe: 7.207 ± 0.0
9.009SerGly: 9.009 ± 1.229
0.0SerHis: 0.0 ± 0.0
1.802SerIle: 1.802 ± 1.229
5.405SerLys: 5.405 ± 1.229
5.405SerLeu: 5.405 ± 3.686
1.802SerMet: 1.802 ± 1.229
7.207SerAsn: 7.207 ± 0.0
0.0SerPro: 0.0 ± 0.0
0.0SerGln: 0.0 ± 0.0
3.604SerArg: 3.604 ± 2.458
0.0SerSer: 0.0 ± 0.0
5.405SerThr: 5.405 ± 1.229
1.802SerVal: 1.802 ± 1.229
1.802SerTrp: 1.802 ± 1.229
5.405SerTyr: 5.405 ± 3.686
0.0SerXaa: 0.0 ± 0.0
Thr
1.802ThrAla: 1.802 ± 1.229
0.0ThrCys: 0.0 ± 0.0
5.405ThrAsp: 5.405 ± 1.229
1.802ThrGlu: 1.802 ± 1.229
1.802ThrPhe: 1.802 ± 1.229
5.405ThrGly: 5.405 ± 1.229
0.0ThrHis: 0.0 ± 0.0
3.604ThrIle: 3.604 ± 0.0
3.604ThrLys: 3.604 ± 0.0
9.009ThrLeu: 9.009 ± 1.229
1.802ThrMet: 1.802 ± 1.229
1.802ThrAsn: 1.802 ± 1.229
5.405ThrPro: 5.405 ± 1.229
1.802ThrGln: 1.802 ± 1.229
3.604ThrArg: 3.604 ± 2.458
9.009ThrSer: 9.009 ± 1.229
5.405ThrThr: 5.405 ± 3.686
1.802ThrVal: 1.802 ± 1.229
3.604ThrTrp: 3.604 ± 2.458
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.802ValAla: 1.802 ± 1.229
1.802ValCys: 1.802 ± 1.229
1.802ValAsp: 1.802 ± 1.229
1.802ValGlu: 1.802 ± 1.229
1.802ValPhe: 1.802 ± 1.229
5.405ValGly: 5.405 ± 1.229
0.0ValHis: 0.0 ± 0.0
3.604ValIle: 3.604 ± 2.458
1.802ValLys: 1.802 ± 1.229
0.0ValLeu: 0.0 ± 0.0
3.604ValMet: 3.604 ± 1.229
3.604ValAsn: 3.604 ± 0.0
3.604ValPro: 3.604 ± 2.458
5.405ValGln: 5.405 ± 1.229
5.405ValArg: 5.405 ± 1.229
5.405ValSer: 5.405 ± 1.229
5.405ValThr: 5.405 ± 1.229
3.604ValVal: 3.604 ± 0.0
0.0ValTrp: 0.0 ± 0.0
3.604ValTyr: 3.604 ± 2.458
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.802TrpPhe: 1.802 ± 1.229
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
3.604TrpIle: 3.604 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.802TrpLeu: 1.802 ± 1.229
0.0TrpMet: 0.0 ± 0.0
1.802TrpAsn: 1.802 ± 1.229
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
5.405TrpArg: 5.405 ± 3.686
1.802TrpSer: 1.802 ± 1.229
1.802TrpThr: 1.802 ± 1.229
0.0TrpVal: 0.0 ± 0.0
1.802TrpTrp: 1.802 ± 1.229
1.802TrpTyr: 1.802 ± 1.229
0.0TrpXaa: 0.0 ± 0.0
Tyr
9.009TyrAla: 9.009 ± 3.686
3.604TyrCys: 3.604 ± 2.458
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
3.604TyrPhe: 3.604 ± 0.0
1.802TyrGly: 1.802 ± 1.229
0.0TyrHis: 0.0 ± 0.0
3.604TyrIle: 3.604 ± 0.0
1.802TyrLys: 1.802 ± 1.229
1.802TyrLeu: 1.802 ± 1.229
1.802TyrMet: 1.802 ± 1.229
3.604TyrAsn: 3.604 ± 2.458
1.802TyrPro: 1.802 ± 1.229
0.0TyrGln: 0.0 ± 0.0
5.405TyrArg: 5.405 ± 1.229
0.0TyrSer: 0.0 ± 0.0
1.802TyrThr: 1.802 ± 1.229
1.802TyrVal: 1.802 ± 1.229
0.0TyrTrp: 0.0 ± 0.0
5.405TyrTyr: 5.405 ± 1.229
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (556 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski