Amino acid dipepetide frequency for Bombyx mori densovirus 3 (isolate Silkworm/China/Zhenjiang/-) (BmDNV-3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.035AlaAla: 2.035 ± 0.957
0.872AlaCys: 0.872 ± 0.374
2.616AlaAsp: 2.616 ± 1.044
2.326AlaGlu: 2.326 ± 0.392
2.326AlaPhe: 2.326 ± 0.583
3.198AlaGly: 3.198 ± 0.855
0.581AlaHis: 0.581 ± 0.419
2.616AlaIle: 2.616 ± 0.85
3.488AlaLys: 3.488 ± 0.858
3.779AlaLeu: 3.779 ± 0.559
0.0AlaMet: 0.0 ± 0.0
2.326AlaAsn: 2.326 ± 1.034
2.326AlaPro: 2.326 ± 0.7
1.453AlaGln: 1.453 ± 0.435
2.035AlaArg: 2.035 ± 0.975
3.779AlaSer: 3.779 ± 1.36
2.907AlaThr: 2.907 ± 0.75
2.035AlaVal: 2.035 ± 0.626
0.581AlaTrp: 0.581 ± 0.335
2.326AlaTyr: 2.326 ± 0.449
0.0AlaXaa: 0.0 ± 0.0
Cys
0.581CysAla: 0.581 ± 0.335
0.0CysCys: 0.0 ± 0.0
0.872CysAsp: 0.872 ± 0.351
1.163CysGlu: 1.163 ± 0.526
0.581CysPhe: 0.581 ± 0.365
0.291CysGly: 0.291 ± 0.296
0.0CysHis: 0.0 ± 0.0
1.744CysIle: 1.744 ± 0.333
1.744CysLys: 1.744 ± 0.629
1.453CysLeu: 1.453 ± 0.434
0.581CysMet: 0.581 ± 0.419
1.744CysAsn: 1.744 ± 0.527
0.291CysPro: 0.291 ± 0.235
0.581CysGln: 0.581 ± 0.335
1.163CysArg: 1.163 ± 0.462
1.163CysSer: 1.163 ± 0.565
0.872CysThr: 0.872 ± 0.374
1.163CysVal: 1.163 ± 0.56
0.0CysTrp: 0.0 ± 0.0
1.163CysTyr: 1.163 ± 0.683
0.0CysXaa: 0.0 ± 0.0
Asp
1.744AspAla: 1.744 ± 0.512
1.163AspCys: 1.163 ± 0.676
3.488AspAsp: 3.488 ± 1.33
2.907AspGlu: 2.907 ± 1.033
2.326AspPhe: 2.326 ± 0.935
3.198AspGly: 3.198 ± 0.77
0.291AspHis: 0.291 ± 0.21
7.558AspIle: 7.558 ± 1.47
2.616AspLys: 2.616 ± 1.582
4.07AspLeu: 4.07 ± 1.163
0.872AspMet: 0.872 ± 0.374
6.395AspAsn: 6.395 ± 1.614
2.907AspPro: 2.907 ± 1.123
1.744AspGln: 1.744 ± 0.991
2.326AspArg: 2.326 ± 0.564
4.07AspSer: 4.07 ± 1.52
2.616AspThr: 2.616 ± 1.185
5.814AspVal: 5.814 ± 1.178
1.453AspTrp: 1.453 ± 0.455
3.779AspTyr: 3.779 ± 1.105
0.0AspXaa: 0.0 ± 0.0
Glu
3.488GluAla: 3.488 ± 0.541
0.291GluCys: 0.291 ± 0.21
4.942GluAsp: 4.942 ± 0.978
4.942GluGlu: 4.942 ± 2.173
2.616GluPhe: 2.616 ± 0.784
1.744GluGly: 1.744 ± 0.594
0.581GluHis: 0.581 ± 0.388
3.488GluIle: 3.488 ± 1.184
2.326GluLys: 2.326 ± 0.742
5.233GluLeu: 5.233 ± 0.986
1.453GluMet: 1.453 ± 0.587
3.198GluAsn: 3.198 ± 0.832
2.326GluPro: 2.326 ± 0.865
1.744GluGln: 1.744 ± 0.523
2.326GluArg: 2.326 ± 0.547
2.907GluSer: 2.907 ± 0.966
3.198GluThr: 3.198 ± 0.838
4.36GluVal: 4.36 ± 1.032
0.872GluTrp: 0.872 ± 0.423
3.488GluTyr: 3.488 ± 1.136
0.0GluXaa: 0.0 ± 0.0
Phe
0.872PheAla: 0.872 ± 0.704
2.616PheCys: 2.616 ± 0.52
3.779PheAsp: 3.779 ± 0.705
2.326PheGlu: 2.326 ± 0.736
0.581PhePhe: 0.581 ± 0.469
2.035PheGly: 2.035 ± 0.673
2.035PheHis: 2.035 ± 0.572
4.651PheIle: 4.651 ± 1.405
5.233PheLys: 5.233 ± 1.417
4.651PheLeu: 4.651 ± 0.982
0.872PheMet: 0.872 ± 0.526
6.686PheAsn: 6.686 ± 0.574
0.581PhePro: 0.581 ± 0.368
1.453PheGln: 1.453 ± 0.598
2.326PheArg: 2.326 ± 1.008
2.907PheSer: 2.907 ± 0.437
2.616PheThr: 2.616 ± 1.083
2.035PheVal: 2.035 ± 0.884
0.0PheTrp: 0.0 ± 0.0
2.616PheTyr: 2.616 ± 1.322
0.0PheXaa: 0.0 ± 0.0
Gly
1.744GlyAla: 1.744 ± 0.776
0.291GlyCys: 0.291 ± 0.309
2.616GlyAsp: 2.616 ± 0.415
3.779GlyGlu: 3.779 ± 0.858
2.616GlyPhe: 2.616 ± 0.844
3.779GlyGly: 3.779 ± 3.199
0.291GlyHis: 0.291 ± 0.309
4.07GlyIle: 4.07 ± 0.721
3.488GlyLys: 3.488 ± 1.053
3.779GlyLeu: 3.779 ± 0.816
0.581GlyMet: 0.581 ± 0.346
3.779GlyAsn: 3.779 ± 1.544
1.744GlyPro: 1.744 ± 0.993
1.744GlyGln: 1.744 ± 0.512
1.453GlyArg: 1.453 ± 0.705
6.395GlySer: 6.395 ± 1.657
3.488GlyThr: 3.488 ± 0.621
2.616GlyVal: 2.616 ± 0.493
0.581GlyTrp: 0.581 ± 0.491
2.907GlyTyr: 2.907 ± 0.631
0.0GlyXaa: 0.0 ± 0.0
His
0.872HisAla: 0.872 ± 0.378
0.581HisCys: 0.581 ± 0.314
1.163HisAsp: 1.163 ± 0.391
0.291HisGlu: 0.291 ± 0.326
0.291HisPhe: 0.291 ± 0.21
0.581HisGly: 0.581 ± 0.335
0.291HisHis: 0.291 ± 0.21
0.872HisIle: 0.872 ± 0.629
1.163HisLys: 1.163 ± 0.624
0.872HisLeu: 0.872 ± 0.52
0.291HisMet: 0.291 ± 0.21
2.035HisAsn: 2.035 ± 0.896
0.291HisPro: 0.291 ± 0.21
0.581HisGln: 0.581 ± 0.232
0.0HisArg: 0.0 ± 0.0
1.453HisSer: 1.453 ± 0.783
1.163HisThr: 1.163 ± 0.475
0.581HisVal: 0.581 ± 0.419
0.0HisTrp: 0.0 ± 0.0
1.163HisTyr: 1.163 ± 0.452
0.0HisXaa: 0.0 ± 0.0
Ile
3.198IleAla: 3.198 ± 0.941
2.035IleCys: 2.035 ± 0.845
4.651IleAsp: 4.651 ± 1.02
5.814IleGlu: 5.814 ± 0.934
3.198IlePhe: 3.198 ± 1.168
3.488IleGly: 3.488 ± 0.797
2.326IleHis: 2.326 ± 1.375
7.849IleIle: 7.849 ± 1.634
5.523IleLys: 5.523 ± 0.702
4.651IleLeu: 4.651 ± 1.165
0.291IleMet: 0.291 ± 0.235
7.267IleAsn: 7.267 ± 2.254
6.105IlePro: 6.105 ± 1.025
2.616IleGln: 2.616 ± 0.845
6.395IleArg: 6.395 ± 0.898
6.395IleSer: 6.395 ± 2.203
5.814IleThr: 5.814 ± 1.128
4.07IleVal: 4.07 ± 1.551
0.872IleTrp: 0.872 ± 0.374
4.07IleTyr: 4.07 ± 1.226
0.0IleXaa: 0.0 ± 0.0
Lys
2.907LysAla: 2.907 ± 0.92
1.453LysCys: 1.453 ± 0.632
5.523LysAsp: 5.523 ± 2.435
1.453LysGlu: 1.453 ± 0.732
3.779LysPhe: 3.779 ± 1.108
4.07LysGly: 4.07 ± 2.104
1.744LysHis: 1.744 ± 0.572
4.942LysIle: 4.942 ± 0.848
2.907LysLys: 2.907 ± 1.61
5.523LysLeu: 5.523 ± 1.934
0.872LysMet: 0.872 ± 0.376
3.488LysAsn: 3.488 ± 0.805
2.907LysPro: 2.907 ± 0.706
2.326LysGln: 2.326 ± 0.503
3.198LysArg: 3.198 ± 0.905
5.523LysSer: 5.523 ± 1.051
3.779LysThr: 3.779 ± 0.673
2.326LysVal: 2.326 ± 0.644
1.744LysTrp: 1.744 ± 0.764
4.07LysTyr: 4.07 ± 1.471
0.0LysXaa: 0.0 ± 0.0
Leu
5.814LeuAla: 5.814 ± 1.502
0.872LeuCys: 0.872 ± 0.382
6.395LeuAsp: 6.395 ± 1.493
6.395LeuGlu: 6.395 ± 0.93
4.651LeuPhe: 4.651 ± 0.933
3.198LeuGly: 3.198 ± 0.801
1.744LeuHis: 1.744 ± 0.705
5.814LeuIle: 5.814 ± 1.019
4.07LeuLys: 4.07 ± 0.711
5.523LeuLeu: 5.523 ± 0.896
1.453LeuMet: 1.453 ± 0.619
6.395LeuAsn: 6.395 ± 1.438
2.616LeuPro: 2.616 ± 0.838
2.326LeuGln: 2.326 ± 0.808
3.779LeuArg: 3.779 ± 1.177
7.558LeuSer: 7.558 ± 1.181
6.686LeuThr: 6.686 ± 0.863
2.907LeuVal: 2.907 ± 0.578
0.872LeuTrp: 0.872 ± 0.48
4.36LeuTyr: 4.36 ± 0.293
0.0LeuXaa: 0.0 ± 0.0
Met
0.581MetAla: 0.581 ± 0.424
0.0MetCys: 0.0 ± 0.0
1.744MetAsp: 1.744 ± 0.338
0.872MetGlu: 0.872 ± 0.48
0.581MetPhe: 0.581 ± 0.232
0.291MetGly: 0.291 ± 0.296
0.291MetHis: 0.291 ± 0.21
1.163MetIle: 1.163 ± 0.452
1.744MetLys: 1.744 ± 0.628
1.744MetLeu: 1.744 ± 0.627
0.291MetMet: 0.291 ± 0.309
1.453MetAsn: 1.453 ± 0.351
1.453MetPro: 1.453 ± 0.586
0.291MetGln: 0.291 ± 0.21
0.581MetArg: 0.581 ± 0.446
0.872MetSer: 0.872 ± 0.298
0.872MetThr: 0.872 ± 0.497
0.0MetVal: 0.0 ± 0.0
0.581MetTrp: 0.581 ± 0.491
0.581MetTyr: 0.581 ± 0.419
0.0MetXaa: 0.0 ± 0.0
Asn
2.035AsnAla: 2.035 ± 0.464
2.035AsnCys: 2.035 ± 0.618
4.07AsnAsp: 4.07 ± 1.538
3.488AsnGlu: 3.488 ± 0.82
7.267AsnPhe: 7.267 ± 1.085
3.198AsnGly: 3.198 ± 1.171
0.291AsnHis: 0.291 ± 0.296
8.14AsnIle: 8.14 ± 1.308
6.105AsnLys: 6.105 ± 1.91
5.523AsnLeu: 5.523 ± 1.421
1.163AsnMet: 1.163 ± 0.376
9.012AsnAsn: 9.012 ± 1.417
3.779AsnPro: 3.779 ± 1.423
3.488AsnGln: 3.488 ± 1.153
4.36AsnArg: 4.36 ± 1.2
4.942AsnSer: 4.942 ± 0.702
4.36AsnThr: 4.36 ± 0.77
5.523AsnVal: 5.523 ± 0.679
0.581AsnTrp: 0.581 ± 0.415
2.326AsnTyr: 2.326 ± 0.702
0.0AsnXaa: 0.0 ± 0.0
Pro
2.326ProAla: 2.326 ± 1.451
0.291ProCys: 0.291 ± 0.296
2.035ProAsp: 2.035 ± 0.906
2.616ProGlu: 2.616 ± 0.545
2.326ProPhe: 2.326 ± 0.641
2.616ProGly: 2.616 ± 0.81
0.872ProHis: 0.872 ± 0.228
5.233ProIle: 5.233 ± 1.32
2.326ProLys: 2.326 ± 1.049
2.907ProLeu: 2.907 ± 0.629
0.872ProMet: 0.872 ± 0.526
2.326ProAsn: 2.326 ± 0.532
0.872ProPro: 0.872 ± 0.378
1.453ProGln: 1.453 ± 0.587
1.453ProArg: 1.453 ± 0.948
3.779ProSer: 3.779 ± 1.71
2.326ProThr: 2.326 ± 0.677
1.744ProVal: 1.744 ± 0.492
0.291ProTrp: 0.291 ± 0.235
2.326ProTyr: 2.326 ± 0.547
0.0ProXaa: 0.0 ± 0.0
Gln
0.581GlnAla: 0.581 ± 0.335
0.291GlnCys: 0.291 ± 0.235
1.453GlnAsp: 1.453 ± 0.351
3.198GlnGlu: 3.198 ± 1.354
1.163GlnPhe: 1.163 ± 0.73
0.872GlnGly: 0.872 ± 0.587
0.581GlnHis: 0.581 ± 0.27
2.907GlnIle: 2.907 ± 0.679
2.035GlnLys: 2.035 ± 0.555
4.942GlnLeu: 4.942 ± 1.464
0.872GlnMet: 0.872 ± 0.69
2.035GlnAsn: 2.035 ± 0.855
0.872GlnPro: 0.872 ± 0.587
0.872GlnGln: 0.872 ± 0.714
2.035GlnArg: 2.035 ± 0.53
0.872GlnSer: 0.872 ± 0.407
2.616GlnThr: 2.616 ± 1.098
1.453GlnVal: 1.453 ± 0.565
0.581GlnTrp: 0.581 ± 0.335
2.035GlnTyr: 2.035 ± 0.405
0.0GlnXaa: 0.0 ± 0.0
Arg
2.907ArgAla: 2.907 ± 0.934
0.581ArgCys: 0.581 ± 0.469
4.07ArgAsp: 4.07 ± 0.99
3.198ArgGlu: 3.198 ± 1.027
2.326ArgPhe: 2.326 ± 1.219
3.198ArgGly: 3.198 ± 0.831
0.291ArgHis: 0.291 ± 0.21
3.488ArgIle: 3.488 ± 0.826
2.616ArgLys: 2.616 ± 0.6
4.942ArgLeu: 4.942 ± 1.674
0.581ArgMet: 0.581 ± 0.365
4.07ArgAsn: 4.07 ± 0.741
0.872ArgPro: 0.872 ± 0.508
2.035ArgGln: 2.035 ± 0.978
0.872ArgArg: 0.872 ± 0.416
3.198ArgSer: 3.198 ± 1.561
2.035ArgThr: 2.035 ± 1.063
1.744ArgVal: 1.744 ± 0.575
0.0ArgTrp: 0.0 ± 0.0
3.198ArgTyr: 3.198 ± 1.057
0.0ArgXaa: 0.0 ± 0.0
Ser
5.233SerAla: 5.233 ± 2.234
1.163SerCys: 1.163 ± 0.375
3.779SerAsp: 3.779 ± 1.584
1.744SerGlu: 1.744 ± 0.989
5.523SerPhe: 5.523 ± 1.258
4.942SerGly: 4.942 ± 1.306
0.581SerHis: 0.581 ± 0.27
5.523SerIle: 5.523 ± 0.782
6.977SerLys: 6.977 ± 1.346
8.14SerLeu: 8.14 ± 1.414
1.453SerMet: 1.453 ± 0.573
6.105SerAsn: 6.105 ± 2.186
2.326SerPro: 2.326 ± 0.658
0.581SerGln: 0.581 ± 0.335
3.488SerArg: 3.488 ± 1.416
5.814SerSer: 5.814 ± 1.234
5.523SerThr: 5.523 ± 0.94
2.616SerVal: 2.616 ± 0.653
0.872SerTrp: 0.872 ± 0.48
2.326SerTyr: 2.326 ± 0.668
0.0SerXaa: 0.0 ± 0.0
Thr
1.744ThrAla: 1.744 ± 0.561
0.872ThrCys: 0.872 ± 0.466
2.616ThrAsp: 2.616 ± 0.966
2.907ThrGlu: 2.907 ± 0.521
3.198ThrPhe: 3.198 ± 0.707
5.523ThrGly: 5.523 ± 1.874
0.581ThrHis: 0.581 ± 0.314
6.105ThrIle: 6.105 ± 1.45
2.907ThrLys: 2.907 ± 1.79
4.942ThrLeu: 4.942 ± 1.369
1.744ThrMet: 1.744 ± 0.416
4.36ThrAsn: 4.36 ± 0.876
4.651ThrPro: 4.651 ± 0.768
2.616ThrGln: 2.616 ± 0.599
3.488ThrArg: 3.488 ± 1.868
4.651ThrSer: 4.651 ± 1.074
4.942ThrThr: 4.942 ± 1.084
3.779ThrVal: 3.779 ± 1.349
0.291ThrTrp: 0.291 ± 0.296
2.326ThrTyr: 2.326 ± 0.732
0.0ThrXaa: 0.0 ± 0.0
Val
1.744ValAla: 1.744 ± 0.647
0.872ValCys: 0.872 ± 0.351
1.744ValAsp: 1.744 ± 0.532
2.616ValGlu: 2.616 ± 0.929
3.488ValPhe: 3.488 ± 0.905
2.035ValGly: 2.035 ± 0.823
0.872ValHis: 0.872 ± 0.652
5.814ValIle: 5.814 ± 0.944
2.326ValLys: 2.326 ± 0.686
4.942ValLeu: 4.942 ± 0.595
0.581ValMet: 0.581 ± 0.446
4.07ValAsn: 4.07 ± 1.129
2.035ValPro: 2.035 ± 0.815
3.488ValGln: 3.488 ± 1.381
1.453ValArg: 1.453 ± 0.814
2.616ValSer: 2.616 ± 0.729
3.198ValThr: 3.198 ± 0.707
2.035ValVal: 2.035 ± 0.405
0.291ValTrp: 0.291 ± 0.21
2.907ValTyr: 2.907 ± 0.681
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.291TrpCys: 0.291 ± 0.37
0.872TrpAsp: 0.872 ± 0.351
0.581TrpGlu: 0.581 ± 0.592
0.291TrpPhe: 0.291 ± 0.21
1.453TrpGly: 1.453 ± 0.645
0.0TrpHis: 0.0 ± 0.0
0.872TrpIle: 0.872 ± 0.526
0.872TrpLys: 0.872 ± 0.496
0.872TrpLeu: 0.872 ± 0.228
0.291TrpMet: 0.291 ± 0.235
1.163TrpAsn: 1.163 ± 0.83
0.291TrpPro: 0.291 ± 0.37
0.0TrpGln: 0.0 ± 0.0
0.291TrpArg: 0.291 ± 0.326
1.744TrpSer: 1.744 ± 0.619
0.291TrpThr: 0.291 ± 0.235
0.581TrpVal: 0.581 ± 0.232
0.0TrpTrp: 0.0 ± 0.0
0.291TrpTyr: 0.291 ± 0.37
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.198TyrAla: 3.198 ± 0.804
0.581TyrCys: 0.581 ± 0.419
2.907TyrAsp: 2.907 ± 1.149
2.907TyrGlu: 2.907 ± 0.834
1.744TyrPhe: 1.744 ± 0.606
2.035TyrGly: 2.035 ± 0.555
0.291TyrHis: 0.291 ± 0.296
3.779TyrIle: 3.779 ± 1.297
4.07TyrLys: 4.07 ± 1.01
5.233TyrLeu: 5.233 ± 1.121
0.581TyrMet: 0.581 ± 0.365
3.779TyrAsn: 3.779 ± 1.347
1.744TyrPro: 1.744 ± 0.546
0.872TyrGln: 0.872 ± 0.926
3.198TyrArg: 3.198 ± 1.414
4.07TyrSer: 4.07 ± 1.201
4.942TyrThr: 4.942 ± 1.078
1.744TyrVal: 1.744 ± 0.713
0.581TyrTrp: 0.581 ± 0.365
6.105TyrTyr: 6.105 ± 1.498
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3441 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski