Amino acid dipepetide frequency for Jeotgalibacillus campisalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.877AlaAla: 6.877 ± 0.123
0.564AlaCys: 0.564 ± 0.026
3.653AlaAsp: 3.653 ± 0.065
4.994AlaGlu: 4.994 ± 0.092
3.455AlaPhe: 3.455 ± 0.059
5.956AlaGly: 5.956 ± 0.09
1.368AlaHis: 1.368 ± 0.041
5.687AlaIle: 5.687 ± 0.076
4.211AlaLys: 4.211 ± 0.078
7.41AlaLeu: 7.41 ± 0.1
2.117AlaMet: 2.117 ± 0.046
2.443AlaAsn: 2.443 ± 0.053
2.159AlaPro: 2.159 ± 0.044
2.495AlaGln: 2.495 ± 0.057
2.707AlaArg: 2.707 ± 0.051
4.594AlaSer: 4.594 ± 0.067
3.566AlaThr: 3.566 ± 0.286
5.957AlaVal: 5.957 ± 0.081
0.659AlaTrp: 0.659 ± 0.028
2.257AlaTyr: 2.257 ± 0.047
0.0AlaXaa: 0.0 ± 0.0
Cys
0.404CysAla: 0.404 ± 0.021
0.079CysCys: 0.079 ± 0.009
0.367CysAsp: 0.367 ± 0.02
0.436CysGlu: 0.436 ± 0.023
0.281CysPhe: 0.281 ± 0.016
0.568CysGly: 0.568 ± 0.026
0.184CysHis: 0.184 ± 0.013
0.441CysIle: 0.441 ± 0.021
0.308CysLys: 0.308 ± 0.019
0.636CysLeu: 0.636 ± 0.024
0.188CysMet: 0.188 ± 0.012
0.23CysAsn: 0.23 ± 0.016
0.319CysPro: 0.319 ± 0.017
0.202CysGln: 0.202 ± 0.014
0.292CysArg: 0.292 ± 0.019
0.485CysSer: 0.485 ± 0.021
0.354CysThr: 0.354 ± 0.019
0.362CysVal: 0.362 ± 0.02
0.058CysTrp: 0.058 ± 0.008
0.217CysTyr: 0.217 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
3.361AspAla: 3.361 ± 0.066
0.358AspCys: 0.358 ± 0.02
2.466AspAsp: 2.466 ± 0.051
4.75AspGlu: 4.75 ± 0.08
2.384AspPhe: 2.384 ± 0.045
3.592AspGly: 3.592 ± 0.059
1.462AspHis: 1.462 ± 0.043
3.626AspIle: 3.626 ± 0.057
2.643AspLys: 2.643 ± 0.053
5.399AspLeu: 5.399 ± 0.065
1.334AspMet: 1.334 ± 0.037
1.611AspAsn: 1.611 ± 0.042
2.26AspPro: 2.26 ± 0.052
2.55AspGln: 2.55 ± 0.052
2.588AspArg: 2.588 ± 0.051
2.972AspSer: 2.972 ± 0.052
2.401AspThr: 2.401 ± 0.053
3.632AspVal: 3.632 ± 0.063
0.723AspTrp: 0.723 ± 0.028
2.092AspTyr: 2.092 ± 0.047
0.0AspXaa: 0.0 ± 0.0
Glu
5.789GluAla: 5.789 ± 0.099
0.354GluCys: 0.354 ± 0.016
4.275GluAsp: 4.275 ± 0.081
8.221GluGlu: 8.221 ± 0.135
2.579GluPhe: 2.579 ± 0.048
4.767GluGly: 4.767 ± 0.077
1.479GluHis: 1.479 ± 0.041
5.45GluIle: 5.45 ± 0.078
6.394GluLys: 6.394 ± 0.093
7.382GluLeu: 7.382 ± 0.108
2.452GluMet: 2.452 ± 0.055
3.563GluAsn: 3.563 ± 0.068
2.14GluPro: 2.14 ± 0.049
3.461GluGln: 3.461 ± 0.06
3.637GluArg: 3.637 ± 0.063
3.953GluSer: 3.953 ± 0.061
4.001GluThr: 4.001 ± 0.07
5.072GluVal: 5.072 ± 0.076
0.998GluTrp: 0.998 ± 0.033
2.175GluTyr: 2.175 ± 0.043
0.0GluXaa: 0.0 ± 0.0
Phe
3.044PheAla: 3.044 ± 0.057
0.333PheCys: 0.333 ± 0.019
2.394PheAsp: 2.394 ± 0.047
2.985PheGlu: 2.985 ± 0.053
2.357PhePhe: 2.357 ± 0.062
3.172PheGly: 3.172 ± 0.06
1.003PheHis: 1.003 ± 0.028
3.897PheIle: 3.897 ± 0.075
2.405PheLys: 2.405 ± 0.051
4.509PheLeu: 4.509 ± 0.086
1.212PheMet: 1.212 ± 0.038
1.917PheAsn: 1.917 ± 0.044
1.659PhePro: 1.659 ± 0.039
1.493PheGln: 1.493 ± 0.036
1.558PheArg: 1.558 ± 0.039
3.446PheSer: 3.446 ± 0.061
2.75PheThr: 2.75 ± 0.055
3.0PheVal: 3.0 ± 0.065
0.481PheTrp: 0.481 ± 0.023
1.68PheTyr: 1.68 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
5.547GlyAla: 5.547 ± 0.3
0.581GlyCys: 0.581 ± 0.023
3.395GlyAsp: 3.395 ± 0.066
4.825GlyGlu: 4.825 ± 0.083
3.359GlyPhe: 3.359 ± 0.061
4.871GlyGly: 4.871 ± 0.084
1.374GlyHis: 1.374 ± 0.038
5.646GlyIle: 5.646 ± 0.085
4.671GlyLys: 4.671 ± 0.074
6.645GlyLeu: 6.645 ± 0.082
2.164GlyMet: 2.164 ± 0.051
2.492GlyAsn: 2.492 ± 0.048
1.967GlyPro: 1.967 ± 0.081
2.239GlyGln: 2.239 ± 0.051
2.731GlyArg: 2.731 ± 0.056
4.339GlySer: 4.339 ± 0.067
3.998GlyThr: 3.998 ± 0.065
5.144GlyVal: 5.144 ± 0.184
0.817GlyTrp: 0.817 ± 0.028
2.647GlyTyr: 2.647 ± 0.057
0.0GlyXaa: 0.0 ± 0.0
His
1.479HisAla: 1.479 ± 0.039
0.188HisCys: 0.188 ± 0.015
1.112HisAsp: 1.112 ± 0.038
1.524HisGlu: 1.524 ± 0.039
1.121HisPhe: 1.121 ± 0.031
1.42HisGly: 1.42 ± 0.044
0.689HisHis: 0.689 ± 0.026
1.405HisIle: 1.405 ± 0.04
1.062HisLys: 1.062 ± 0.036
2.226HisLeu: 2.226 ± 0.054
0.506HisMet: 0.506 ± 0.022
0.784HisAsn: 0.784 ± 0.026
1.184HisPro: 1.184 ± 0.037
0.921HisGln: 0.921 ± 0.029
0.918HisArg: 0.918 ± 0.035
1.477HisSer: 1.477 ± 0.04
1.112HisThr: 1.112 ± 0.035
1.427HisVal: 1.427 ± 0.044
0.232HisTrp: 0.232 ± 0.017
0.907HisTyr: 0.907 ± 0.028
0.0HisXaa: 0.0 ± 0.0
Ile
5.962IleAla: 5.962 ± 0.09
0.536IleCys: 0.536 ± 0.026
4.244IleAsp: 4.244 ± 0.061
5.908IleGlu: 5.908 ± 0.087
3.121IlePhe: 3.121 ± 0.072
5.674IleGly: 5.674 ± 0.078
1.725IleHis: 1.725 ± 0.038
5.298IleIle: 5.298 ± 0.105
4.194IleLys: 4.194 ± 0.071
6.946IleLeu: 6.946 ± 0.112
1.775IleMet: 1.775 ± 0.042
3.021IleAsn: 3.021 ± 0.056
3.164IlePro: 3.164 ± 0.071
3.094IleGln: 3.094 ± 0.059
3.146IleArg: 3.146 ± 0.053
4.884IleSer: 4.884 ± 0.071
4.108IleThr: 4.108 ± 0.067
5.133IleVal: 5.133 ± 0.083
0.673IleTrp: 0.673 ± 0.026
2.167IleTyr: 2.167 ± 0.045
0.0IleXaa: 0.0 ± 0.0
Lys
4.379LysAla: 4.379 ± 0.078
0.253LysCys: 0.253 ± 0.019
3.552LysAsp: 3.552 ± 0.061
6.676LysGlu: 6.676 ± 0.092
1.663LysPhe: 1.663 ± 0.042
4.282LysGly: 4.282 ± 0.069
1.271LysHis: 1.271 ± 0.037
4.237LysIle: 4.237 ± 0.056
5.856LysLys: 5.856 ± 0.081
5.167LysLeu: 5.167 ± 0.072
2.14LysMet: 2.14 ± 0.045
3.017LysAsn: 3.017 ± 0.057
2.092LysPro: 2.092 ± 0.056
2.697LysGln: 2.697 ± 0.051
3.314LysArg: 3.314 ± 0.061
3.394LysSer: 3.394 ± 0.051
3.463LysThr: 3.463 ± 0.059
3.995LysVal: 3.995 ± 0.063
0.872LysTrp: 0.872 ± 0.03
1.597LysTyr: 1.597 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
7.345LeuAla: 7.345 ± 0.096
0.602LeuCys: 0.602 ± 0.026
4.857LeuAsp: 4.857 ± 0.07
6.634LeuGlu: 6.634 ± 0.1
5.003LeuPhe: 5.003 ± 0.095
6.125LeuGly: 6.125 ± 0.088
2.115LeuHis: 2.115 ± 0.048
7.365LeuIle: 7.365 ± 0.109
6.166LeuLys: 6.166 ± 0.086
10.474LeuLeu: 10.474 ± 0.143
2.609LeuMet: 2.609 ± 0.052
4.17LeuAsn: 4.17 ± 0.061
4.005LeuPro: 4.005 ± 0.065
3.553LeuGln: 3.553 ± 0.059
3.547LeuArg: 3.547 ± 0.056
7.345LeuSer: 7.345 ± 0.101
5.996LeuThr: 5.996 ± 0.077
6.146LeuVal: 6.146 ± 0.094
0.885LeuTrp: 0.885 ± 0.029
3.155LeuTyr: 3.155 ± 0.063
0.0LeuXaa: 0.0 ± 0.0
Met
2.081MetAla: 2.081 ± 0.042
0.136MetCys: 0.136 ± 0.011
1.61MetAsp: 1.61 ± 0.037
2.132MetGlu: 2.132 ± 0.049
0.958MetPhe: 0.958 ± 0.03
1.796MetGly: 1.796 ± 0.046
0.446MetHis: 0.446 ± 0.024
2.344MetIle: 2.344 ± 0.046
2.483MetLys: 2.483 ± 0.052
2.539MetLeu: 2.539 ± 0.056
0.912MetMet: 0.912 ± 0.03
1.687MetAsn: 1.687 ± 0.038
1.04MetPro: 1.04 ± 0.034
0.948MetGln: 0.948 ± 0.033
1.101MetArg: 1.101 ± 0.034
1.727MetSer: 1.727 ± 0.042
1.821MetThr: 1.821 ± 0.041
1.828MetVal: 1.828 ± 0.045
0.218MetTrp: 0.218 ± 0.015
0.689MetTyr: 0.689 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
2.7AsnAla: 2.7 ± 0.059
0.254AsnCys: 0.254 ± 0.016
2.164AsnAsp: 2.164 ± 0.04
3.743AsnGlu: 3.743 ± 0.066
1.511AsnPhe: 1.511 ± 0.039
3.198AsnGly: 3.198 ± 0.056
1.017AsnHis: 1.017 ± 0.032
2.741AsnIle: 2.741 ± 0.059
2.516AsnLys: 2.516 ± 0.058
3.568AsnLeu: 3.568 ± 0.053
1.088AsnMet: 1.088 ± 0.031
1.619AsnAsn: 1.619 ± 0.053
1.988AsnPro: 1.988 ± 0.042
1.943AsnGln: 1.943 ± 0.043
2.096AsnArg: 2.096 ± 0.046
2.158AsnSer: 2.158 ± 0.046
1.932AsnThr: 1.932 ± 0.043
2.75AsnVal: 2.75 ± 0.047
0.516AsnTrp: 0.516 ± 0.019
1.322AsnTyr: 1.322 ± 0.037
0.0AsnXaa: 0.0 ± 0.0
Pro
2.749ProAla: 2.749 ± 0.061
0.203ProCys: 0.203 ± 0.015
2.276ProAsp: 2.276 ± 0.054
3.118ProGlu: 3.118 ± 0.057
2.08ProPhe: 2.08 ± 0.042
2.354ProGly: 2.354 ± 0.053
0.838ProHis: 0.838 ± 0.032
2.584ProIle: 2.584 ± 0.052
1.849ProLys: 1.849 ± 0.044
3.618ProLeu: 3.618 ± 0.071
0.878ProMet: 0.878 ± 0.028
1.372ProAsn: 1.372 ± 0.039
1.084ProPro: 1.084 ± 0.03
1.166ProGln: 1.166 ± 0.039
1.065ProArg: 1.065 ± 0.039
2.615ProSer: 2.615 ± 0.05
1.824ProThr: 1.824 ± 0.082
3.116ProVal: 3.116 ± 0.053
0.381ProTrp: 0.381 ± 0.019
1.398ProTyr: 1.398 ± 0.044
0.0ProXaa: 0.0 ± 0.0
Gln
2.947GlnAla: 2.947 ± 0.051
0.203GlnCys: 0.203 ± 0.014
1.862GlnAsp: 1.862 ± 0.045
2.967GlnGlu: 2.967 ± 0.055
1.71GlnPhe: 1.71 ± 0.041
2.271GlnGly: 2.271 ± 0.048
0.861GlnHis: 0.861 ± 0.032
2.438GlnIle: 2.438 ± 0.046
2.704GlnLys: 2.704 ± 0.057
4.011GlnLeu: 4.011 ± 0.071
1.182GlnMet: 1.182 ± 0.036
1.573GlnAsn: 1.573 ± 0.041
1.297GlnPro: 1.297 ± 0.035
1.885GlnGln: 1.885 ± 0.048
1.577GlnArg: 1.577 ± 0.038
2.635GlnSer: 2.635 ± 0.052
2.158GlnThr: 2.158 ± 0.046
2.31GlnVal: 2.31 ± 0.049
0.466GlnTrp: 0.466 ± 0.02
1.293GlnTyr: 1.293 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
2.521ArgAla: 2.521 ± 0.046
0.253ArgCys: 0.253 ± 0.016
2.147ArgAsp: 2.147 ± 0.043
3.382ArgGlu: 3.382 ± 0.063
2.091ArgPhe: 2.091 ± 0.041
2.356ArgGly: 2.356 ± 0.041
0.853ArgHis: 0.853 ± 0.029
3.071ArgIle: 3.071 ± 0.061
3.09ArgLys: 3.09 ± 0.05
4.044ArgLeu: 4.044 ± 0.071
1.375ArgMet: 1.375 ± 0.036
1.807ArgAsn: 1.807 ± 0.034
1.349ArgPro: 1.349 ± 0.043
1.557ArgGln: 1.557 ± 0.039
1.781ArgArg: 1.781 ± 0.048
2.646ArgSer: 2.646 ± 0.044
2.161ArgThr: 2.161 ± 0.045
2.725ArgVal: 2.725 ± 0.051
0.463ArgTrp: 0.463 ± 0.022
1.511ArgTyr: 1.511 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
4.206SerAla: 4.206 ± 0.066
0.395SerCys: 0.395 ± 0.022
3.004SerAsp: 3.004 ± 0.054
4.101SerGlu: 4.101 ± 0.072
3.575SerPhe: 3.575 ± 0.067
4.724SerGly: 4.724 ± 0.078
1.419SerHis: 1.419 ± 0.043
5.493SerIle: 5.493 ± 0.066
3.592SerLys: 3.592 ± 0.067
6.74SerLeu: 6.74 ± 0.092
1.893SerMet: 1.893 ± 0.047
2.476SerAsn: 2.476 ± 0.052
2.368SerPro: 2.368 ± 0.048
2.297SerGln: 2.297 ± 0.057
2.569SerArg: 2.569 ± 0.051
4.7SerSer: 4.7 ± 0.072
3.399SerThr: 3.399 ± 0.068
4.426SerVal: 4.426 ± 0.075
0.707SerTrp: 0.707 ± 0.029
2.233SerTyr: 2.233 ± 0.043
0.0SerXaa: 0.0 ± 0.0
Thr
4.337ThrAla: 4.337 ± 0.071
0.308ThrCys: 0.308 ± 0.019
2.799ThrAsp: 2.799 ± 0.06
3.673ThrGlu: 3.673 ± 0.066
2.583ThrPhe: 2.583 ± 0.051
4.971ThrGly: 4.971 ± 0.533
1.096ThrHis: 1.096 ± 0.031
4.528ThrIle: 4.528 ± 0.072
3.004ThrLys: 3.004 ± 0.06
5.267ThrLeu: 5.267 ± 0.071
1.39ThrMet: 1.39 ± 0.037
2.234ThrAsn: 2.234 ± 0.048
2.22ThrPro: 2.22 ± 0.044
1.528ThrGln: 1.528 ± 0.041
1.875ThrArg: 1.875 ± 0.047
3.366ThrSer: 3.366 ± 0.055
2.776ThrThr: 2.776 ± 0.056
4.225ThrVal: 4.225 ± 0.059
0.48ThrTrp: 0.48 ± 0.023
1.843ThrTyr: 1.843 ± 0.046
0.0ThrXaa: 0.0 ± 0.0
Val
4.618ValAla: 4.618 ± 0.076
0.497ValCys: 0.497 ± 0.024
3.587ValAsp: 3.587 ± 0.063
4.928ValGlu: 4.928 ± 0.084
3.109ValPhe: 3.109 ± 0.066
4.332ValGly: 4.332 ± 0.073
1.472ValHis: 1.472 ± 0.044
5.427ValIle: 5.427 ± 0.072
4.298ValLys: 4.298 ± 0.065
6.976ValLeu: 6.976 ± 0.082
2.028ValMet: 2.028 ± 0.046
2.959ValAsn: 2.959 ± 0.057
2.647ValPro: 2.647 ± 0.045
2.53ValGln: 2.53 ± 0.059
2.703ValArg: 2.703 ± 0.056
4.635ValSer: 4.635 ± 0.077
4.28ValThr: 4.28 ± 0.168
4.733ValVal: 4.733 ± 0.074
0.687ValTrp: 0.687 ± 0.026
2.245ValTyr: 2.245 ± 0.047
0.0ValXaa: 0.0 ± 0.0
Trp
0.633TrpAla: 0.633 ± 0.022
0.065TrpCys: 0.065 ± 0.008
0.54TrpAsp: 0.54 ± 0.023
0.703TrpGlu: 0.703 ± 0.028
0.552TrpPhe: 0.552 ± 0.021
0.684TrpGly: 0.684 ± 0.027
0.226TrpHis: 0.226 ± 0.016
0.934TrpIle: 0.934 ± 0.031
0.705TrpLys: 0.705 ± 0.026
1.239TrpLeu: 1.239 ± 0.044
0.411TrpMet: 0.411 ± 0.018
0.555TrpAsn: 0.555 ± 0.023
0.295TrpPro: 0.295 ± 0.017
0.402TrpGln: 0.402 ± 0.017
0.44TrpArg: 0.44 ± 0.02
0.684TrpSer: 0.684 ± 0.027
0.631TrpThr: 0.631 ± 0.026
0.676TrpVal: 0.676 ± 0.027
0.154TrpTrp: 0.154 ± 0.014
0.34TrpTyr: 0.34 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.15TyrAla: 2.15 ± 0.042
0.251TyrCys: 0.251 ± 0.017
1.902TyrAsp: 1.902 ± 0.047
2.439TyrGlu: 2.439 ± 0.048
1.803TyrPhe: 1.803 ± 0.047
2.341TyrGly: 2.341 ± 0.045
0.796TyrHis: 0.796 ± 0.031
2.162TyrIle: 2.162 ± 0.048
1.766TyrLys: 1.766 ± 0.04
3.3TyrLeu: 3.3 ± 0.066
0.843TyrMet: 0.843 ± 0.029
1.293TyrAsn: 1.293 ± 0.037
1.329TyrPro: 1.329 ± 0.032
1.39TyrGln: 1.39 ± 0.039
1.536TyrArg: 1.536 ± 0.037
2.261TyrSer: 2.261 ± 0.052
1.773TyrThr: 1.773 ± 0.044
2.035TyrVal: 2.035 ± 0.038
0.399TyrTrp: 0.399 ± 0.021
1.321TyrTyr: 1.321 ± 0.038
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3729 proteins (1041369 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski