Amino acid dipepetide frequency for Paracoccus liaowanqingii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.694AlaAla: 18.694 ± 0.165	1.059AlaCys: 1.059 ± 0.032	7.426AlaAsp: 7.426 ± 0.08	8.023AlaGlu: 8.023 ± 0.1	4.195AlaPhe: 4.195 ± 0.063	11.642AlaGly: 11.642 ± 0.115	2.491AlaHis: 2.491 ± 0.047	6.162AlaIle: 6.162 ± 0.073	2.69AlaLys: 2.69 ± 0.056	15.151AlaLeu: 15.151 ± 0.127	4.088AlaMet: 4.088 ± 0.054	2.369AlaAsn: 2.369 ± 0.045	6.65AlaPro: 6.65 ± 0.091	5.138AlaGln: 5.138 ± 0.067	10.49AlaArg: 10.49 ± 0.104	5.795AlaSer: 5.795 ± 0.063	6.463AlaThr: 6.463 ± 0.071	9.012AlaVal: 9.012 ± 0.092	1.665AlaTrp: 1.665 ± 0.037	2.305AlaTyr: 2.305 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.006CysAla: 1.006 ± 0.028	0.113CysCys: 0.113 ± 0.009	0.573CysAsp: 0.573 ± 0.019	0.357CysGlu: 0.357 ± 0.015	0.268CysPhe: 0.268 ± 0.015	0.869CysGly: 0.869 ± 0.029	0.262CysHis: 0.262 ± 0.015	0.404CysIle: 0.404 ± 0.018	0.16CysLys: 0.16 ± 0.012	0.876CysLeu: 0.876 ± 0.026	0.153CysMet: 0.153 ± 0.012	0.175CysAsn: 0.175 ± 0.012	0.496CysPro: 0.496 ± 0.023	0.232CysGln: 0.232 ± 0.011	0.606CysArg: 0.606 ± 0.024	0.387CysSer: 0.387 ± 0.018	0.392CysThr: 0.392 ± 0.019	0.519CysVal: 0.519 ± 0.021	0.129CysTrp: 0.129 ± 0.011	0.154CysTyr: 0.154 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.557AspAla: 7.557 ± 0.083	0.494AspCys: 0.494 ± 0.017	3.446AspAsp: 3.446 ± 0.064	3.188AspGlu: 3.188 ± 0.054	2.175AspPhe: 2.175 ± 0.039	5.443AspGly: 5.443 ± 0.079	1.588AspHis: 1.588 ± 0.038	2.77AspIle: 2.77 ± 0.051	1.258AspLys: 1.258 ± 0.035	7.397AspLeu: 7.397 ± 0.083	1.646AspMet: 1.646 ± 0.037	1.145AspAsn: 1.145 ± 0.032	4.368AspPro: 4.368 ± 0.064	2.185AspGln: 2.185 ± 0.046	5.61AspArg: 5.61 ± 0.064	2.29AspSer: 2.29 ± 0.05	2.612AspThr: 2.612 ± 0.058	3.706AspVal: 3.706 ± 0.057	1.341AspTrp: 1.341 ± 0.031	1.502AspTyr: 1.502 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	8.092GluAla: 8.092 ± 0.088	0.3GluCys: 0.3 ± 0.017	3.094GluAsp: 3.094 ± 0.05	2.59GluGlu: 2.59 ± 0.05	1.611GluPhe: 1.611 ± 0.031	5.005GluGly: 5.005 ± 0.062	0.928GluHis: 0.928 ± 0.026	3.04GluIle: 3.04 ± 0.052	1.334GluLys: 1.334 ± 0.039	4.574GluLeu: 4.574 ± 0.055	1.611GluMet: 1.611 ± 0.038	1.27GluAsn: 1.27 ± 0.031	2.389GluPro: 2.389 ± 0.048	1.717GluGln: 1.717 ± 0.034	3.854GluArg: 3.854 ± 0.054	1.791GluSer: 1.791 ± 0.039	3.2GluThr: 3.2 ± 0.054	3.975GluVal: 3.975 ± 0.06	0.651GluTrp: 0.651 ± 0.024	0.897GluTyr: 0.897 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.408PheAla: 4.408 ± 0.064	0.357PheCys: 0.357 ± 0.015	2.646PheAsp: 2.646 ± 0.052	1.761PheGlu: 1.761 ± 0.045	1.237PhePhe: 1.237 ± 0.029	3.554PheGly: 3.554 ± 0.055	0.734PheHis: 0.734 ± 0.024	1.516PheIle: 1.516 ± 0.035	0.672PheLys: 0.672 ± 0.021	3.401PheLeu: 3.401 ± 0.058	0.78PheMet: 0.78 ± 0.027	0.863PheAsn: 0.863 ± 0.025	1.565PhePro: 1.565 ± 0.039	1.046PheGln: 1.046 ± 0.029	2.273PheArg: 2.273 ± 0.041	1.885PheSer: 1.885 ± 0.039	1.935PheThr: 1.935 ± 0.037	2.497PheVal: 2.497 ± 0.041	0.566PheTrp: 0.566 ± 0.022	0.807PheTyr: 0.807 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	10.602GlyAla: 10.602 ± 0.096	0.837GlyCys: 0.837 ± 0.026	4.772GlyAsp: 4.772 ± 0.076	4.103GlyGlu: 4.103 ± 0.061	3.567GlyPhe: 3.567 ± 0.054	7.576GlyGly: 7.576 ± 0.104	2.113GlyHis: 2.113 ± 0.04	4.551GlyIle: 4.551 ± 0.067	2.296GlyLys: 2.296 ± 0.042	9.88GlyLeu: 9.88 ± 0.094	2.701GlyMet: 2.701 ± 0.05	2.058GlyAsn: 2.058 ± 0.058	4.282GlyPro: 4.282 ± 0.065	3.694GlyGln: 3.694 ± 0.064	6.868GlyArg: 6.868 ± 0.078	4.284GlySer: 4.284 ± 0.063	4.861GlyThr: 4.861 ± 0.058	6.16GlyVal: 6.16 ± 0.068	1.62GlyTrp: 1.62 ± 0.034	2.079GlyTyr: 2.079 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.572HisAla: 2.572 ± 0.05	0.227HisCys: 0.227 ± 0.013	1.522HisAsp: 1.522 ± 0.041	1.004HisGlu: 1.004 ± 0.029	0.733HisPhe: 0.733 ± 0.024	1.978HisGly: 1.978 ± 0.042	0.569HisHis: 0.569 ± 0.028	0.805HisIle: 0.805 ± 0.023	0.404HisLys: 0.404 ± 0.018	2.41HisLeu: 2.41 ± 0.048	0.496HisMet: 0.496 ± 0.021	0.388HisAsn: 0.388 ± 0.016	1.57HisPro: 1.57 ± 0.036	0.645HisGln: 0.645 ± 0.023	1.578HisArg: 1.578 ± 0.035	0.914HisSer: 0.914 ± 0.027	0.713HisThr: 0.713 ± 0.024	1.604HisVal: 1.604 ± 0.037	0.312HisTrp: 0.312 ± 0.017	0.515HisTyr: 0.515 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.295IleAla: 7.295 ± 0.084	0.527IleCys: 0.527 ± 0.021	3.516IleAsp: 3.516 ± 0.056	3.108IleGlu: 3.108 ± 0.051	1.744IlePhe: 1.744 ± 0.041	4.742IleGly: 4.742 ± 0.062	0.975IleHis: 0.975 ± 0.027	2.137IleIle: 2.137 ± 0.052	0.986IleLys: 0.986 ± 0.026	5.03IleLeu: 5.03 ± 0.066	1.084IleMet: 1.084 ± 0.032	1.154IleAsn: 1.154 ± 0.035	2.456IlePro: 2.456 ± 0.049	1.139IleGln: 1.139 ± 0.029	3.647IleArg: 3.647 ± 0.048	2.674IleSer: 2.674 ± 0.044	2.903IleThr: 2.903 ± 0.055	3.691IleVal: 3.691 ± 0.055	0.741IleTrp: 0.741 ± 0.025	1.033IleTyr: 1.033 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.838LysAla: 2.838 ± 0.052	0.128LysCys: 0.128 ± 0.01	1.291LysAsp: 1.291 ± 0.035	0.921LysGlu: 0.921 ± 0.03	0.615LysPhe: 0.615 ± 0.021	2.006LysGly: 2.006 ± 0.041	0.407LysHis: 0.407 ± 0.02	1.243LysIle: 1.243 ± 0.032	0.744LysLys: 0.744 ± 0.029	2.172LysLeu: 2.172 ± 0.046	0.6LysMet: 0.6 ± 0.025	0.58LysAsn: 0.58 ± 0.024	1.278LysPro: 1.278 ± 0.037	0.68LysGln: 0.68 ± 0.024	1.701LysArg: 1.701 ± 0.041	1.351LysSer: 1.351 ± 0.033	1.423LysThr: 1.423 ± 0.035	1.634LysVal: 1.634 ± 0.042	0.259LysTrp: 0.259 ± 0.015	0.456LysTyr: 0.456 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	14.734LeuAla: 14.734 ± 0.123	0.9LeuCys: 0.9 ± 0.028	6.704LeuAsp: 6.704 ± 0.069	4.75LeuGlu: 4.75 ± 0.071	3.298LeuPhe: 3.298 ± 0.052	8.721LeuGly: 8.721 ± 0.096	2.061LeuHis: 2.061 ± 0.043	5.495LeuIle: 5.495 ± 0.077	2.306LeuLys: 2.306 ± 0.054	9.292LeuLeu: 9.292 ± 0.126	2.823LeuMet: 2.823 ± 0.047	2.39LeuAsn: 2.39 ± 0.042	6.413LeuPro: 6.413 ± 0.087	3.185LeuGln: 3.185 ± 0.053	8.068LeuArg: 8.068 ± 0.084	6.824LeuSer: 6.824 ± 0.074	6.769LeuThr: 6.769 ± 0.074	7.214LeuVal: 7.214 ± 0.093	1.325LeuTrp: 1.325 ± 0.029	1.844LeuTyr: 1.844 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.827MetAla: 3.827 ± 0.057	0.165MetCys: 0.165 ± 0.012	1.442MetAsp: 1.442 ± 0.033	1.153MetGlu: 1.153 ± 0.03	0.752MetPhe: 0.752 ± 0.025	2.411MetGly: 2.411 ± 0.048	0.423MetHis: 0.423 ± 0.019	1.598MetIle: 1.598 ± 0.041	0.752MetLys: 0.752 ± 0.027	2.72MetLeu: 2.72 ± 0.05	0.77MetMet: 0.77 ± 0.028	0.747MetAsn: 0.747 ± 0.024	1.62MetPro: 1.62 ± 0.038	0.958MetGln: 0.958 ± 0.029	2.063MetArg: 2.063 ± 0.038	1.684MetSer: 1.684 ± 0.037	2.27MetThr: 2.27 ± 0.043	1.92MetVal: 1.92 ± 0.04	0.251MetTrp: 0.251 ± 0.012	0.295MetTyr: 0.295 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.714AsnAla: 2.714 ± 0.045	0.203AsnCys: 0.203 ± 0.012	1.354AsnAsp: 1.354 ± 0.044	0.946AsnGlu: 0.946 ± 0.027	0.818AsnPhe: 0.818 ± 0.026	1.907AsnGly: 1.907 ± 0.042	0.454AsnHis: 0.454 ± 0.018	1.23AsnIle: 1.23 ± 0.033	0.447AsnLys: 0.447 ± 0.02	2.416AsnLeu: 2.416 ± 0.048	0.547AsnMet: 0.547 ± 0.02	0.569AsnAsn: 0.569 ± 0.026	1.712AsnPro: 1.712 ± 0.04	0.686AsnGln: 0.686 ± 0.021	1.644AsnArg: 1.644 ± 0.037	1.107AsnSer: 1.107 ± 0.03	1.02AsnThr: 1.02 ± 0.031	1.582AsnVal: 1.582 ± 0.041	0.392AsnTrp: 0.392 ± 0.02	0.559AsnTyr: 0.559 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.159ProAla: 7.159 ± 0.086	0.355ProCys: 0.355 ± 0.019	4.491ProAsp: 4.491 ± 0.068	3.913ProGlu: 3.913 ± 0.054	1.901ProPhe: 1.901 ± 0.04	5.256ProGly: 5.256 ± 0.071	1.144ProHis: 1.144 ± 0.031	2.211ProIle: 2.211 ± 0.04	1.194ProLys: 1.194 ± 0.03	5.313ProLeu: 5.313 ± 0.066	1.453ProMet: 1.453 ± 0.036	1.133ProAsn: 1.133 ± 0.031	2.851ProPro: 2.851 ± 0.071	2.005ProGln: 2.005 ± 0.042	3.622ProArg: 3.622 ± 0.056	2.554ProSer: 2.554 ± 0.046	2.524ProThr: 2.524 ± 0.048	4.606ProVal: 4.606 ± 0.063	0.835ProTrp: 0.835 ± 0.028	1.053ProTyr: 1.053 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.89GlnAla: 4.89 ± 0.066	0.166GlnCys: 0.166 ± 0.011	1.97GlnAsp: 1.97 ± 0.038	1.395GlnGlu: 1.395 ± 0.036	1.057GlnPhe: 1.057 ± 0.026	3.299GlnGly: 3.299 ± 0.053	0.625GlnHis: 0.625 ± 0.023	2.263GlnIle: 2.263 ± 0.038	0.804GlnLys: 0.804 ± 0.025	3.041GlnLeu: 3.041 ± 0.052	1.188GlnMet: 1.188 ± 0.031	0.78GlnAsn: 0.78 ± 0.024	1.992GlnPro: 1.992 ± 0.044	1.238GlnGln: 1.238 ± 0.033	2.296GlnArg: 2.296 ± 0.044	1.624GlnSer: 1.624 ± 0.036	1.969GlnThr: 1.969 ± 0.042	2.821GlnVal: 2.821 ± 0.046	0.381GlnTrp: 0.381 ± 0.017	0.531GlnTyr: 0.531 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	9.538ArgAla: 9.538 ± 0.094	0.524ArgCys: 0.524 ± 0.023	5.011ArgAsp: 5.011 ± 0.064	3.638ArgGlu: 3.638 ± 0.051	2.792ArgPhe: 2.792 ± 0.047	5.171ArgGly: 5.171 ± 0.07	1.949ArgHis: 1.949 ± 0.041	4.5ArgIle: 4.5 ± 0.056	1.795ArgLys: 1.795 ± 0.037	8.705ArgLeu: 8.705 ± 0.09	2.296ArgMet: 2.296 ± 0.044	1.73ArgAsn: 1.73 ± 0.037	4.172ArgPro: 4.172 ± 0.058	2.857ArgGln: 2.857 ± 0.047	5.96ArgArg: 5.96 ± 0.082	3.486ArgSer: 3.486 ± 0.053	3.347ArgThr: 3.347 ± 0.055	4.976ArgVal: 4.976 ± 0.061	1.083ArgTrp: 1.083 ± 0.03	1.455ArgTyr: 1.455 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	5.683SerAla: 5.683 ± 0.071	0.416SerCys: 0.416 ± 0.019	3.176SerAsp: 3.176 ± 0.053	2.532SerGlu: 2.532 ± 0.046	2.073SerPhe: 2.073 ± 0.046	5.289SerGly: 5.289 ± 0.068	1.035SerHis: 1.035 ± 0.027	2.342SerIle: 2.342 ± 0.045	1.101SerLys: 1.101 ± 0.031	5.06SerLeu: 5.06 ± 0.074	1.268SerMet: 1.268 ± 0.032	1.138SerAsn: 1.138 ± 0.032	2.689SerPro: 2.689 ± 0.054	1.6SerGln: 1.6 ± 0.033	3.482SerArg: 3.482 ± 0.051	2.492SerSer: 2.492 ± 0.044	2.369SerThr: 2.369 ± 0.046	3.657SerVal: 3.657 ± 0.055	0.709SerTrp: 0.709 ± 0.023	1.167SerTyr: 1.167 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.57ThrAla: 6.57 ± 0.086	0.45ThrCys: 0.45 ± 0.019	3.337ThrAsp: 3.337 ± 0.05	2.928ThrGlu: 2.928 ± 0.048	1.717ThrPhe: 1.717 ± 0.041	5.716ThrGly: 5.716 ± 0.072	1.097ThrHis: 1.097 ± 0.03	2.674ThrIle: 2.674 ± 0.045	1.075ThrLys: 1.075 ± 0.029	5.975ThrLeu: 5.975 ± 0.072	1.281ThrMet: 1.281 ± 0.033	1.185ThrAsn: 1.185 ± 0.032	3.58ThrPro: 3.58 ± 0.052	1.629ThrGln: 1.629 ± 0.035	3.944ThrArg: 3.944 ± 0.062	2.532ThrSer: 2.532 ± 0.042	2.867ThrThr: 2.867 ± 0.059	4.129ThrVal: 4.129 ± 0.055	0.648ThrTrp: 0.648 ± 0.022	1.07ThrTyr: 1.07 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	9.441ValAla: 9.441 ± 0.084	0.579ValCys: 0.579 ± 0.023	3.768ValAsp: 3.768 ± 0.059	4.086ValGlu: 4.086 ± 0.059	2.624ValPhe: 2.624 ± 0.045	5.321ValGly: 5.321 ± 0.061	1.301ValHis: 1.301 ± 0.034	4.176ValIle: 4.176 ± 0.058	1.583ValLys: 1.583 ± 0.039	7.729ValLeu: 7.729 ± 0.085	2.207ValMet: 2.207 ± 0.043	1.741ValAsn: 1.741 ± 0.034	3.665ValPro: 3.665 ± 0.055	2.288ValGln: 2.288 ± 0.038	4.454ValArg: 4.454 ± 0.059	3.78ValSer: 3.78 ± 0.053	4.987ValThr: 4.987 ± 0.065	5.537ValVal: 5.537 ± 0.071	0.968ValTrp: 0.968 ± 0.028	1.274ValTyr: 1.274 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.464TrpAla: 1.464 ± 0.034	0.126TrpCys: 0.126 ± 0.01	0.764TrpAsp: 0.764 ± 0.025	0.534TrpGlu: 0.534 ± 0.018	0.579TrpPhe: 0.579 ± 0.022	1.023TrpGly: 1.023 ± 0.029	0.348TrpHis: 0.348 ± 0.016	0.723TrpIle: 0.723 ± 0.024	0.341TrpLys: 0.341 ± 0.017	1.825TrpLeu: 1.825 ± 0.039	0.423TrpMet: 0.423 ± 0.019	0.407TrpAsn: 0.407 ± 0.019	0.783TrpPro: 0.783 ± 0.028	0.758TrpGln: 0.758 ± 0.023	1.277TrpArg: 1.277 ± 0.032	0.827TrpSer: 0.827 ± 0.029	0.889TrpThr: 0.889 ± 0.027	0.847TrpVal: 0.847 ± 0.024	0.227TrpTrp: 0.227 ± 0.014	0.228TrpTyr: 0.228 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.423TyrAla: 2.423 ± 0.045	0.201TyrCys: 0.201 ± 0.014	1.419TyrAsp: 1.419 ± 0.039	0.992TyrGlu: 0.992 ± 0.028	0.751TyrPhe: 0.751 ± 0.026	1.976TyrGly: 1.976 ± 0.037	0.458TyrHis: 0.458 ± 0.021	0.741TyrIle: 0.741 ± 0.024	0.383TyrLys: 0.383 ± 0.021	2.15TyrLeu: 2.15 ± 0.039	0.404TyrMet: 0.404 ± 0.02	0.486TyrAsn: 0.486 ± 0.02	1.042TyrPro: 1.042 ± 0.03	0.649TyrGln: 0.649 ± 0.023	1.549TyrArg: 1.549 ± 0.033	0.998TyrSer: 0.998 ± 0.026	0.889TyrThr: 0.889 ± 0.024	1.418TyrVal: 1.418 ± 0.033	0.293TyrTrp: 0.293 ± 0.015	0.502TyrTyr: 0.502 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4493 proteins (1306414 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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