Amino acid dipepetide frequency for Thogoto virus (isolate SiAr 126) (Tho)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.475AlaAla: 2.475 ± 0.673
2.2AlaCys: 2.2 ± 0.48
1.925AlaAsp: 1.925 ± 0.578
5.776AlaGlu: 5.776 ± 1.088
3.025AlaPhe: 3.025 ± 1.019
2.75AlaGly: 2.75 ± 0.704
1.1AlaHis: 1.1 ± 0.468
3.85AlaIle: 3.85 ± 1.225
4.125AlaLys: 4.125 ± 0.564
6.326AlaLeu: 6.326 ± 1.083
2.2AlaMet: 2.2 ± 0.834
1.925AlaAsn: 1.925 ± 0.602
3.3AlaPro: 3.3 ± 0.677
0.825AlaGln: 0.825 ± 0.518
1.65AlaArg: 1.65 ± 0.445
4.675AlaSer: 4.675 ± 0.923
3.3AlaThr: 3.3 ± 0.376
3.3AlaVal: 3.3 ± 0.659
0.275AlaTrp: 0.275 ± 0.241
3.025AlaTyr: 3.025 ± 0.83
0.0AlaXaa: 0.0 ± 0.0
Cys
0.825CysAla: 0.825 ± 0.532
0.825CysCys: 0.825 ± 0.532
0.55CysAsp: 0.55 ± 0.463
1.1CysGlu: 1.1 ± 0.677
1.375CysPhe: 1.375 ± 0.477
0.825CysGly: 0.825 ± 0.349
0.55CysHis: 0.55 ± 0.482
1.1CysIle: 1.1 ± 0.469
2.475CysLys: 2.475 ± 0.733
1.375CysLeu: 1.375 ± 0.72
0.275CysMet: 0.275 ± 0.217
1.65CysAsn: 1.65 ± 0.791
2.2CysPro: 2.2 ± 1.002
1.375CysGln: 1.375 ± 0.517
1.65CysArg: 1.65 ± 0.544
1.375CysSer: 1.375 ± 0.454
1.375CysThr: 1.375 ± 0.455
0.825CysVal: 0.825 ± 0.493
0.55CysTrp: 0.55 ± 0.331
1.1CysTyr: 1.1 ± 0.593
0.0CysXaa: 0.0 ± 0.0
Asp
1.925AspAla: 1.925 ± 0.591
1.1AspCys: 1.1 ± 0.602
1.375AspAsp: 1.375 ± 0.509
4.675AspGlu: 4.675 ± 1.208
2.2AspPhe: 2.2 ± 0.702
1.925AspGly: 1.925 ± 0.823
2.475AspHis: 2.475 ± 1.168
3.85AspIle: 3.85 ± 0.178
2.75AspLys: 2.75 ± 0.359
5.776AspLeu: 5.776 ± 0.375
0.55AspMet: 0.55 ± 0.287
2.2AspAsn: 2.2 ± 0.693
3.575AspPro: 3.575 ± 0.538
3.3AspGln: 3.3 ± 0.944
3.025AspArg: 3.025 ± 0.503
4.125AspSer: 4.125 ± 1.146
3.025AspThr: 3.025 ± 0.924
2.2AspVal: 2.2 ± 0.908
1.375AspTrp: 1.375 ± 0.421
1.925AspTyr: 1.925 ± 0.516
0.0AspXaa: 0.0 ± 0.0
Glu
3.3GluAla: 3.3 ± 1.372
1.65GluCys: 1.65 ± 0.605
4.675GluAsp: 4.675 ± 0.942
7.976GluGlu: 7.976 ± 2.096
3.3GluPhe: 3.3 ± 0.717
4.95GluGly: 4.95 ± 1.543
0.825GluHis: 0.825 ± 0.48
5.226GluIle: 5.226 ± 0.444
3.85GluLys: 3.85 ± 0.87
7.701GluLeu: 7.701 ± 1.351
2.475GluMet: 2.475 ± 0.593
2.75GluAsn: 2.75 ± 0.768
3.025GluPro: 3.025 ± 1.052
0.825GluGln: 0.825 ± 0.465
3.3GluArg: 3.3 ± 0.983
3.575GluSer: 3.575 ± 0.653
4.125GluThr: 4.125 ± 0.98
5.226GluVal: 5.226 ± 0.743
1.65GluTrp: 1.65 ± 0.724
1.925GluTyr: 1.925 ± 0.595
0.0GluXaa: 0.0 ± 0.0
Phe
2.2PheAla: 2.2 ± 0.853
1.375PheCys: 1.375 ± 0.587
1.1PheAsp: 1.1 ± 0.643
1.65PheGlu: 1.65 ± 0.766
2.2PhePhe: 2.2 ± 0.651
1.925PheGly: 1.925 ± 0.739
0.825PheHis: 0.825 ± 0.64
2.75PheIle: 2.75 ± 0.933
2.2PheLys: 2.2 ± 0.675
4.125PheLeu: 4.125 ± 0.813
1.925PheMet: 1.925 ± 0.869
2.2PheAsn: 2.2 ± 0.924
0.55PhePro: 0.55 ± 0.335
1.1PheGln: 1.1 ± 0.611
1.925PheArg: 1.925 ± 0.583
5.501PheSer: 5.501 ± 1.186
1.1PheThr: 1.1 ± 0.552
2.475PheVal: 2.475 ± 0.825
0.55PheTrp: 0.55 ± 0.331
1.65PheTyr: 1.65 ± 0.59
0.0PheXaa: 0.0 ± 0.0
Gly
3.025GlyAla: 3.025 ± 0.777
1.375GlyCys: 1.375 ± 0.509
1.375GlyAsp: 1.375 ± 0.74
5.776GlyGlu: 5.776 ± 0.659
1.65GlyPhe: 1.65 ± 0.537
2.2GlyGly: 2.2 ± 0.804
1.1GlyHis: 1.1 ± 0.783
2.2GlyIle: 2.2 ± 0.467
3.3GlyLys: 3.3 ± 0.755
4.125GlyLeu: 4.125 ± 1.244
2.2GlyMet: 2.2 ± 0.749
1.925GlyAsn: 1.925 ± 0.519
3.3GlyPro: 3.3 ± 0.899
1.375GlyGln: 1.375 ± 0.682
3.85GlyArg: 3.85 ± 0.55
4.125GlySer: 4.125 ± 1.084
3.575GlyThr: 3.575 ± 0.383
3.575GlyVal: 3.575 ± 0.936
1.925GlyTrp: 1.925 ± 0.979
1.1GlyTyr: 1.1 ± 0.458
0.0GlyXaa: 0.0 ± 0.0
His
1.375HisAla: 1.375 ± 0.381
0.275HisCys: 0.275 ± 0.273
1.1HisAsp: 1.1 ± 0.304
1.1HisGlu: 1.1 ± 0.263
0.825HisPhe: 0.825 ± 0.345
1.1HisGly: 1.1 ± 0.334
1.1HisHis: 1.1 ± 0.409
0.55HisIle: 0.55 ± 0.277
1.1HisLys: 1.1 ± 0.486
2.2HisLeu: 2.2 ± 0.996
1.1HisMet: 1.1 ± 0.434
0.825HisAsn: 0.825 ± 0.512
0.55HisPro: 0.55 ± 0.296
1.375HisGln: 1.375 ± 0.951
1.1HisArg: 1.1 ± 0.49
2.475HisSer: 2.475 ± 0.503
2.75HisThr: 2.75 ± 0.72
2.2HisVal: 2.2 ± 0.633
0.275HisTrp: 0.275 ± 0.241
0.55HisTyr: 0.55 ± 0.296
0.0HisXaa: 0.0 ± 0.0
Ile
3.575IleAla: 3.575 ± 0.358
1.925IleCys: 1.925 ± 0.828
4.4IleAsp: 4.4 ± 0.973
4.125IleGlu: 4.125 ± 1.24
1.1IlePhe: 1.1 ± 0.544
2.75IleGly: 2.75 ± 0.99
2.2IleHis: 2.2 ± 0.46
3.3IleIle: 3.3 ± 0.828
3.85IleLys: 3.85 ± 0.627
4.675IleLeu: 4.675 ± 0.797
1.375IleMet: 1.375 ± 0.471
2.2IleAsn: 2.2 ± 0.736
1.925IlePro: 1.925 ± 0.617
3.575IleGln: 3.575 ± 0.23
3.3IleArg: 3.3 ± 0.256
6.051IleSer: 6.051 ± 1.125
2.2IleThr: 2.2 ± 1.146
2.2IleVal: 2.2 ± 0.663
1.1IleTrp: 1.1 ± 0.632
2.475IleTyr: 2.475 ± 0.933
0.0IleXaa: 0.0 ± 0.0
Lys
3.3LysAla: 3.3 ± 0.908
0.55LysCys: 0.55 ± 0.287
3.025LysAsp: 3.025 ± 1.344
4.675LysGlu: 4.675 ± 0.826
2.2LysPhe: 2.2 ± 0.609
4.125LysGly: 4.125 ± 0.728
1.1LysHis: 1.1 ± 0.402
4.675LysIle: 4.675 ± 0.979
4.675LysLys: 4.675 ± 1.093
6.601LysLeu: 6.601 ± 1.939
1.375LysMet: 1.375 ± 0.435
2.75LysAsn: 2.75 ± 0.894
3.025LysPro: 3.025 ± 0.758
2.2LysGln: 2.2 ± 0.586
7.151LysArg: 7.151 ± 1.603
3.3LysSer: 3.3 ± 1.01
1.925LysThr: 1.925 ± 0.932
4.125LysVal: 4.125 ± 1.075
1.1LysTrp: 1.1 ± 0.448
3.85LysTyr: 3.85 ± 1.142
0.0LysXaa: 0.0 ± 0.0
Leu
6.326LeuAla: 6.326 ± 1.719
1.65LeuCys: 1.65 ± 0.463
6.601LeuAsp: 6.601 ± 1.548
6.876LeuGlu: 6.876 ± 0.941
2.2LeuPhe: 2.2 ± 0.893
3.85LeuGly: 3.85 ± 0.861
3.3LeuHis: 3.3 ± 1.149
5.226LeuIle: 5.226 ± 0.975
6.876LeuLys: 6.876 ± 0.864
11.826LeuLeu: 11.826 ± 2.551
0.825LeuMet: 0.825 ± 0.315
3.3LeuAsn: 3.3 ± 0.893
4.125LeuPro: 4.125 ± 0.749
3.575LeuGln: 3.575 ± 0.941
4.675LeuArg: 4.675 ± 0.71
7.976LeuSer: 7.976 ± 1.0
3.85LeuThr: 3.85 ± 0.997
5.776LeuVal: 5.776 ± 1.498
1.1LeuTrp: 1.1 ± 0.52
2.2LeuTyr: 2.2 ± 0.928
0.0LeuXaa: 0.0 ± 0.0
Met
1.925MetAla: 1.925 ± 0.505
0.55MetCys: 0.55 ± 0.278
1.375MetAsp: 1.375 ± 0.617
3.025MetGlu: 3.025 ± 0.853
1.1MetPhe: 1.1 ± 0.623
2.75MetGly: 2.75 ± 0.878
0.825MetHis: 0.825 ± 0.269
0.825MetIle: 0.825 ± 0.531
0.825MetLys: 0.825 ± 0.429
1.1MetLeu: 1.1 ± 0.669
1.1MetMet: 1.1 ± 0.532
0.825MetAsn: 0.825 ± 0.491
0.825MetPro: 0.825 ± 0.415
0.0MetGln: 0.0 ± 0.0
2.475MetArg: 2.475 ± 0.511
2.2MetSer: 2.2 ± 0.669
1.375MetThr: 1.375 ± 0.387
1.65MetVal: 1.65 ± 0.544
0.275MetTrp: 0.275 ± 0.213
1.375MetTyr: 1.375 ± 0.477
0.0MetXaa: 0.0 ± 0.0
Asn
1.65AsnAla: 1.65 ± 0.463
1.375AsnCys: 1.375 ± 0.517
0.275AsnAsp: 0.275 ± 0.22
1.375AsnGlu: 1.375 ± 0.595
1.65AsnPhe: 1.65 ± 0.946
2.475AsnGly: 2.475 ± 0.873
0.825AsnHis: 0.825 ± 0.365
2.2AsnIle: 2.2 ± 0.445
3.575AsnLys: 3.575 ± 0.74
4.4AsnLeu: 4.4 ± 0.88
1.1AsnMet: 1.1 ± 0.443
2.75AsnAsn: 2.75 ± 0.965
4.125AsnPro: 4.125 ± 1.047
0.825AsnGln: 0.825 ± 0.573
1.65AsnArg: 1.65 ± 0.506
1.925AsnSer: 1.925 ± 0.533
3.575AsnThr: 3.575 ± 0.792
3.3AsnVal: 3.3 ± 1.06
0.825AsnTrp: 0.825 ± 0.317
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.675ProAla: 4.675 ± 0.788
0.275ProCys: 0.275 ± 0.241
4.125ProAsp: 4.125 ± 0.564
2.475ProGlu: 2.475 ± 0.673
1.65ProPhe: 1.65 ± 0.316
1.65ProGly: 1.65 ± 0.317
0.825ProHis: 0.825 ± 0.269
1.925ProIle: 1.925 ± 0.591
3.025ProLys: 3.025 ± 1.198
4.4ProLeu: 4.4 ± 1.217
0.55ProMet: 0.55 ± 0.287
1.65ProAsn: 1.65 ± 0.628
2.2ProPro: 2.2 ± 0.837
1.65ProGln: 1.65 ± 0.42
4.125ProArg: 4.125 ± 0.661
4.4ProSer: 4.4 ± 0.906
2.75ProThr: 2.75 ± 0.641
3.575ProVal: 3.575 ± 0.708
1.1ProTrp: 1.1 ± 0.443
1.375ProTyr: 1.375 ± 0.65
0.0ProXaa: 0.0 ± 0.0
Gln
1.1GlnAla: 1.1 ± 0.44
1.1GlnCys: 1.1 ± 0.517
2.2GlnAsp: 2.2 ± 0.762
3.85GlnGlu: 3.85 ± 0.917
1.65GlnPhe: 1.65 ± 0.66
1.65GlnGly: 1.65 ± 0.641
0.55GlnHis: 0.55 ± 0.306
2.475GlnIle: 2.475 ± 0.999
1.1GlnLys: 1.1 ± 0.832
2.2GlnLeu: 2.2 ± 0.863
2.475GlnMet: 2.475 ± 0.528
0.825GlnAsn: 0.825 ± 0.308
1.1GlnPro: 1.1 ± 0.396
0.55GlnGln: 0.55 ± 0.463
1.925GlnArg: 1.925 ± 0.375
2.75GlnSer: 2.75 ± 1.014
3.85GlnThr: 3.85 ± 0.971
3.85GlnVal: 3.85 ± 1.406
1.1GlnTrp: 1.1 ± 0.55
1.925GlnTyr: 1.925 ± 0.358
0.0GlnXaa: 0.0 ± 0.0
Arg
4.675ArgAla: 4.675 ± 1.137
1.1ArgCys: 1.1 ± 0.662
4.675ArgAsp: 4.675 ± 0.658
4.675ArgGlu: 4.675 ± 0.931
2.475ArgPhe: 2.475 ± 0.567
2.75ArgGly: 2.75 ± 0.554
0.55ArgHis: 0.55 ± 0.272
3.85ArgIle: 3.85 ± 0.797
4.675ArgLys: 4.675 ± 1.158
3.575ArgLeu: 3.575 ± 1.104
0.55ArgMet: 0.55 ± 0.277
1.1ArgAsn: 1.1 ± 0.601
3.3ArgPro: 3.3 ± 0.958
2.2ArgGln: 2.2 ± 0.29
4.125ArgArg: 4.125 ± 1.253
5.226ArgSer: 5.226 ± 1.175
3.3ArgThr: 3.3 ± 0.83
3.025ArgVal: 3.025 ± 0.808
0.825ArgTrp: 0.825 ± 0.363
1.925ArgTyr: 1.925 ± 0.685
0.0ArgXaa: 0.0 ± 0.0
Ser
6.326SerAla: 6.326 ± 1.627
2.2SerCys: 2.2 ± 0.29
4.95SerAsp: 4.95 ± 1.193
3.3SerGlu: 3.3 ± 0.659
3.575SerPhe: 3.575 ± 0.472
5.226SerGly: 5.226 ± 1.675
0.825SerHis: 0.825 ± 0.475
4.675SerIle: 4.675 ± 0.92
7.426SerLys: 7.426 ± 1.406
7.151SerLeu: 7.151 ± 1.507
1.375SerMet: 1.375 ± 0.492
3.3SerAsn: 3.3 ± 1.087
3.025SerPro: 3.025 ± 0.292
3.025SerGln: 3.025 ± 1.021
4.4SerArg: 4.4 ± 1.406
3.3SerSer: 3.3 ± 1.09
3.85SerThr: 3.85 ± 0.987
3.025SerVal: 3.025 ± 0.783
0.825SerTrp: 0.825 ± 0.424
2.75SerTyr: 2.75 ± 0.889
0.0SerXaa: 0.0 ± 0.0
Thr
3.025ThrAla: 3.025 ± 1.006
0.55ThrCys: 0.55 ± 0.316
3.3ThrAsp: 3.3 ± 0.938
2.75ThrGlu: 2.75 ± 0.438
2.2ThrPhe: 2.2 ± 0.62
3.3ThrGly: 3.3 ± 1.097
1.375ThrHis: 1.375 ± 0.232
4.125ThrIle: 4.125 ± 0.944
3.3ThrLys: 3.3 ± 0.721
5.501ThrLeu: 5.501 ± 1.142
1.65ThrMet: 1.65 ± 0.445
2.475ThrAsn: 2.475 ± 0.871
2.475ThrPro: 2.475 ± 0.806
3.025ThrGln: 3.025 ± 0.777
3.3ThrArg: 3.3 ± 1.051
5.226ThrSer: 5.226 ± 0.597
4.675ThrThr: 4.675 ± 0.615
4.95ThrVal: 4.95 ± 1.239
0.275ThrTrp: 0.275 ± 0.22
1.375ThrTyr: 1.375 ± 0.812
0.0ThrXaa: 0.0 ± 0.0
Val
3.85ValAla: 3.85 ± 0.79
2.475ValCys: 2.475 ± 1.316
3.85ValAsp: 3.85 ± 1.397
4.95ValGlu: 4.95 ± 1.248
3.575ValPhe: 3.575 ± 0.717
3.85ValGly: 3.85 ± 0.855
2.475ValHis: 2.475 ± 0.539
2.475ValIle: 2.475 ± 0.774
3.3ValLys: 3.3 ± 0.966
5.226ValLeu: 5.226 ± 1.057
1.375ValMet: 1.375 ± 0.472
2.2ValAsn: 2.2 ± 0.426
3.025ValPro: 3.025 ± 0.811
3.85ValGln: 3.85 ± 1.312
2.75ValArg: 2.75 ± 0.526
3.025ValSer: 3.025 ± 0.979
3.3ValThr: 3.3 ± 0.979
4.675ValVal: 4.675 ± 0.913
0.275ValTrp: 0.275 ± 0.259
3.025ValTyr: 3.025 ± 0.764
0.0ValXaa: 0.0 ± 0.0
Trp
0.55TrpAla: 0.55 ± 0.349
0.0TrpCys: 0.0 ± 0.0
0.825TrpAsp: 0.825 ± 0.415
0.825TrpGlu: 0.825 ± 0.283
0.275TrpPhe: 0.275 ± 0.273
1.375TrpGly: 1.375 ± 0.556
0.275TrpHis: 0.275 ± 0.22
1.925TrpIle: 1.925 ± 0.916
1.65TrpLys: 1.65 ± 0.595
0.55TrpLeu: 0.55 ± 0.296
0.55TrpMet: 0.55 ± 0.463
0.275TrpAsn: 0.275 ± 0.259
0.275TrpPro: 0.275 ± 0.22
1.375TrpGln: 1.375 ± 0.67
0.55TrpArg: 0.55 ± 0.331
0.825TrpSer: 0.825 ± 0.349
1.375TrpThr: 1.375 ± 0.686
2.475TrpVal: 2.475 ± 1.01
0.275TrpTrp: 0.275 ± 0.257
0.825TrpTyr: 0.825 ± 0.409
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.925TyrAla: 1.925 ± 0.677
0.825TyrCys: 0.825 ± 0.365
1.65TyrAsp: 1.65 ± 0.568
1.375TyrGlu: 1.375 ± 0.529
1.1TyrPhe: 1.1 ± 0.669
1.65TyrGly: 1.65 ± 0.716
0.825TyrHis: 0.825 ± 0.317
1.1TyrIle: 1.1 ± 0.524
1.65TyrLys: 1.65 ± 0.513
3.3TyrLeu: 3.3 ± 0.844
1.1TyrMet: 1.1 ± 0.336
2.75TyrAsn: 2.75 ± 0.511
2.475TyrPro: 2.475 ± 0.92
2.2TyrGln: 2.2 ± 0.521
1.65TyrArg: 1.65 ± 0.386
2.475TyrSer: 2.475 ± 0.755
3.575TyrThr: 3.575 ± 0.876
1.375TyrVal: 1.375 ± 0.503
1.375TyrTrp: 1.375 ± 0.545
0.55TyrTyr: 0.55 ± 0.277
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3637 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski