Amino acid dipepetide frequency for Dendrolimus punctatus cypovirus 22

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.926AlaAla: 3.926 ± 0.654
0.705AlaCys: 0.705 ± 0.182
2.718AlaAsp: 2.718 ± 0.505
2.617AlaGlu: 2.617 ± 0.558
2.919AlaPhe: 2.919 ± 0.664
2.214AlaGly: 2.214 ± 0.311
1.61AlaHis: 1.61 ± 0.281
3.825AlaIle: 3.825 ± 0.766
2.315AlaLys: 2.315 ± 0.567
7.448AlaLeu: 7.448 ± 0.854
1.812AlaMet: 1.812 ± 0.379
3.825AlaAsn: 3.825 ± 0.42
2.416AlaPro: 2.416 ± 0.409
2.516AlaGln: 2.516 ± 0.447
3.926AlaArg: 3.926 ± 0.566
4.529AlaSer: 4.529 ± 0.499
4.731AlaThr: 4.731 ± 0.676
2.919AlaVal: 2.919 ± 0.473
0.302AlaTrp: 0.302 ± 0.159
2.315AlaTyr: 2.315 ± 0.588
0.0AlaXaa: 0.0 ± 0.0
Cys
0.805CysAla: 0.805 ± 0.209
0.201CysCys: 0.201 ± 0.144
1.007CysAsp: 1.007 ± 0.328
0.805CysGlu: 0.805 ± 0.235
0.805CysPhe: 0.805 ± 0.224
1.409CysGly: 1.409 ± 0.449
0.403CysHis: 0.403 ± 0.209
0.906CysIle: 0.906 ± 0.337
0.503CysLys: 0.503 ± 0.277
0.906CysLeu: 0.906 ± 0.355
0.101CysMet: 0.101 ± 0.1
0.403CysAsn: 0.403 ± 0.178
0.604CysPro: 0.604 ± 0.263
0.403CysGln: 0.403 ± 0.215
0.604CysArg: 0.604 ± 0.193
1.208CysSer: 1.208 ± 0.362
0.705CysThr: 0.705 ± 0.331
0.604CysVal: 0.604 ± 0.3
0.302CysTrp: 0.302 ± 0.147
0.604CysTyr: 0.604 ± 0.192
0.0CysXaa: 0.0 ± 0.0
Asp
4.127AspAla: 4.127 ± 0.601
0.705AspCys: 0.705 ± 0.258
3.825AspAsp: 3.825 ± 0.604
3.523AspGlu: 3.523 ± 0.504
3.12AspPhe: 3.12 ± 0.425
3.724AspGly: 3.724 ± 0.538
1.812AspHis: 1.812 ± 0.455
5.637AspIle: 5.637 ± 0.61
1.711AspLys: 1.711 ± 0.449
4.529AspLeu: 4.529 ± 0.588
1.208AspMet: 1.208 ± 0.376
2.416AspAsn: 2.416 ± 0.408
2.013AspPro: 2.013 ± 0.436
1.208AspGln: 1.208 ± 0.321
3.724AspArg: 3.724 ± 0.578
3.221AspSer: 3.221 ± 0.613
3.624AspThr: 3.624 ± 0.39
4.831AspVal: 4.831 ± 0.543
0.604AspTrp: 0.604 ± 0.287
2.919AspTyr: 2.919 ± 0.418
0.0AspXaa: 0.0 ± 0.0
Glu
2.718GluAla: 2.718 ± 0.468
0.705GluCys: 0.705 ± 0.337
3.624GluAsp: 3.624 ± 0.489
2.516GluGlu: 2.516 ± 0.437
2.919GluPhe: 2.919 ± 0.647
2.315GluGly: 2.315 ± 0.608
1.51GluHis: 1.51 ± 0.371
4.026GluIle: 4.026 ± 0.383
2.214GluLys: 2.214 ± 0.508
5.838GluLeu: 5.838 ± 0.563
1.208GluMet: 1.208 ± 0.337
3.02GluAsn: 3.02 ± 0.472
1.912GluPro: 1.912 ± 0.567
2.013GluGln: 2.013 ± 0.37
3.221GluArg: 3.221 ± 0.474
2.718GluSer: 2.718 ± 0.417
4.026GluThr: 4.026 ± 0.467
3.221GluVal: 3.221 ± 0.39
0.403GluTrp: 0.403 ± 0.157
2.919GluTyr: 2.919 ± 0.522
0.0GluXaa: 0.0 ± 0.0
Phe
3.02PheAla: 3.02 ± 0.589
0.503PheCys: 0.503 ± 0.277
3.12PheAsp: 3.12 ± 0.561
2.214PheGlu: 2.214 ± 0.479
1.711PhePhe: 1.711 ± 0.322
1.51PheGly: 1.51 ± 0.341
0.604PheHis: 0.604 ± 0.21
2.919PheIle: 2.919 ± 0.393
1.711PheLys: 1.711 ± 0.444
3.624PheLeu: 3.624 ± 0.526
0.705PheMet: 0.705 ± 0.241
2.416PheAsn: 2.416 ± 0.748
2.114PhePro: 2.114 ± 0.385
2.114PheGln: 2.114 ± 0.402
2.416PheArg: 2.416 ± 0.45
4.026PheSer: 4.026 ± 0.486
2.718PheThr: 2.718 ± 0.451
2.214PheVal: 2.214 ± 0.343
0.503PheTrp: 0.503 ± 0.185
1.208PheTyr: 1.208 ± 0.251
0.0PheXaa: 0.0 ± 0.0
Gly
2.718GlyAla: 2.718 ± 0.445
0.805GlyCys: 0.805 ± 0.41
3.322GlyAsp: 3.322 ± 0.476
2.617GlyGlu: 2.617 ± 0.504
1.711GlyPhe: 1.711 ± 0.284
2.818GlyGly: 2.818 ± 0.538
1.208GlyHis: 1.208 ± 0.31
4.227GlyIle: 4.227 ± 0.547
2.718GlyLys: 2.718 ± 0.58
5.033GlyLeu: 5.033 ± 0.726
1.711GlyMet: 1.711 ± 0.49
1.711GlyAsn: 1.711 ± 0.409
0.906GlyPro: 0.906 ± 0.237
2.114GlyGln: 2.114 ± 0.477
2.315GlyArg: 2.315 ± 0.456
2.919GlySer: 2.919 ± 0.487
1.812GlyThr: 1.812 ± 0.379
2.617GlyVal: 2.617 ± 0.532
0.403GlyTrp: 0.403 ± 0.241
2.718GlyTyr: 2.718 ± 0.337
0.0GlyXaa: 0.0 ± 0.0
His
2.013HisAla: 2.013 ± 0.444
0.503HisCys: 0.503 ± 0.19
2.315HisAsp: 2.315 ± 0.289
2.114HisGlu: 2.114 ± 0.58
1.409HisPhe: 1.409 ± 0.372
1.812HisGly: 1.812 ± 0.32
1.208HisHis: 1.208 ± 0.39
2.114HisIle: 2.114 ± 0.426
1.107HisLys: 1.107 ± 0.258
2.516HisLeu: 2.516 ± 0.485
0.201HisMet: 0.201 ± 0.117
0.906HisAsn: 0.906 ± 0.259
2.114HisPro: 2.114 ± 0.39
1.61HisGln: 1.61 ± 0.349
1.812HisArg: 1.812 ± 0.348
2.416HisSer: 2.416 ± 0.495
2.114HisThr: 2.114 ± 0.559
1.409HisVal: 1.409 ± 0.258
0.101HisTrp: 0.101 ± 0.088
1.107HisTyr: 1.107 ± 0.316
0.0HisXaa: 0.0 ± 0.0
Ile
4.227IleAla: 4.227 ± 0.599
0.805IleCys: 0.805 ± 0.342
4.831IleAsp: 4.831 ± 0.638
4.227IleGlu: 4.227 ± 0.659
3.523IlePhe: 3.523 ± 0.576
2.617IleGly: 2.617 ± 0.548
2.516IleHis: 2.516 ± 0.551
5.033IleIle: 5.033 ± 0.806
3.624IleLys: 3.624 ± 0.579
6.543IleLeu: 6.543 ± 0.752
2.516IleMet: 2.516 ± 0.507
3.221IleAsn: 3.221 ± 0.656
4.529IlePro: 4.529 ± 0.556
3.02IleGln: 3.02 ± 0.481
4.429IleArg: 4.429 ± 0.549
4.026IleSer: 4.026 ± 0.461
6.039IleThr: 6.039 ± 0.928
4.328IleVal: 4.328 ± 0.508
0.403IleTrp: 0.403 ± 0.201
3.322IleTyr: 3.322 ± 0.506
0.0IleXaa: 0.0 ± 0.0
Lys
2.919LysAla: 2.919 ± 0.889
0.604LysCys: 0.604 ± 0.211
1.912LysAsp: 1.912 ± 0.487
2.214LysGlu: 2.214 ± 0.498
1.711LysPhe: 1.711 ± 0.329
1.309LysGly: 1.309 ± 0.251
1.007LysHis: 1.007 ± 0.318
2.416LysIle: 2.416 ± 0.581
1.912LysLys: 1.912 ± 0.784
5.335LysLeu: 5.335 ± 0.767
1.409LysMet: 1.409 ± 0.333
2.617LysAsn: 2.617 ± 0.557
2.617LysPro: 2.617 ± 0.707
1.711LysGln: 1.711 ± 0.447
3.624LysArg: 3.624 ± 0.577
2.617LysSer: 2.617 ± 0.512
3.322LysThr: 3.322 ± 0.795
3.12LysVal: 3.12 ± 0.396
0.302LysTrp: 0.302 ± 0.164
1.912LysTyr: 1.912 ± 0.447
0.0LysXaa: 0.0 ± 0.0
Leu
5.939LeuAla: 5.939 ± 1.047
1.107LeuCys: 1.107 ± 0.3
4.227LeuAsp: 4.227 ± 0.49
4.328LeuGlu: 4.328 ± 0.529
3.523LeuPhe: 3.523 ± 0.595
4.227LeuGly: 4.227 ± 0.594
3.221LeuHis: 3.221 ± 0.519
6.945LeuIle: 6.945 ± 0.755
4.227LeuLys: 4.227 ± 0.546
10.468LeuLeu: 10.468 ± 0.847
3.221LeuMet: 3.221 ± 0.558
6.744LeuAsn: 6.744 ± 0.768
5.435LeuPro: 5.435 ± 0.955
4.127LeuGln: 4.127 ± 0.791
5.133LeuArg: 5.133 ± 0.886
7.65LeuSer: 7.65 ± 1.399
6.643LeuThr: 6.643 ± 0.772
4.429LeuVal: 4.429 ± 0.341
0.503LeuTrp: 0.503 ± 0.197
3.322LeuTyr: 3.322 ± 0.651
0.0LeuXaa: 0.0 ± 0.0
Met
1.711MetAla: 1.711 ± 0.5
0.201MetCys: 0.201 ± 0.148
1.107MetAsp: 1.107 ± 0.282
0.705MetGlu: 0.705 ± 0.258
0.604MetPhe: 0.604 ± 0.273
1.007MetGly: 1.007 ± 0.192
0.503MetHis: 0.503 ± 0.184
2.114MetIle: 2.114 ± 0.637
1.51MetLys: 1.51 ± 0.38
2.818MetLeu: 2.818 ± 0.42
0.503MetMet: 0.503 ± 0.22
1.409MetAsn: 1.409 ± 0.325
1.409MetPro: 1.409 ± 0.23
0.906MetGln: 0.906 ± 0.294
1.61MetArg: 1.61 ± 0.426
1.61MetSer: 1.61 ± 0.354
1.61MetThr: 1.61 ± 0.379
1.711MetVal: 1.711 ± 0.421
0.503MetTrp: 0.503 ± 0.206
1.711MetTyr: 1.711 ± 0.463
0.0MetXaa: 0.0 ± 0.0
Asn
3.322AsnAla: 3.322 ± 0.481
1.107AsnCys: 1.107 ± 0.328
3.825AsnAsp: 3.825 ± 0.534
3.221AsnGlu: 3.221 ± 0.533
2.114AsnPhe: 2.114 ± 0.294
2.718AsnGly: 2.718 ± 0.689
1.912AsnHis: 1.912 ± 0.366
4.63AsnIle: 4.63 ± 0.542
1.711AsnLys: 1.711 ± 0.321
4.731AsnLeu: 4.731 ± 0.459
1.107AsnMet: 1.107 ± 0.334
2.919AsnAsn: 2.919 ± 0.391
2.818AsnPro: 2.818 ± 0.651
2.114AsnGln: 2.114 ± 0.618
3.12AsnArg: 3.12 ± 0.425
2.617AsnSer: 2.617 ± 0.445
3.221AsnThr: 3.221 ± 0.745
4.227AsnVal: 4.227 ± 0.703
0.604AsnTrp: 0.604 ± 0.245
2.315AsnTyr: 2.315 ± 0.446
0.0AsnXaa: 0.0 ± 0.0
Pro
1.711ProAla: 1.711 ± 0.487
0.604ProCys: 0.604 ± 0.166
3.322ProAsp: 3.322 ± 0.575
2.214ProGlu: 2.214 ± 0.368
2.114ProPhe: 2.114 ± 0.476
1.912ProGly: 1.912 ± 0.457
1.61ProHis: 1.61 ± 0.361
3.422ProIle: 3.422 ± 0.747
2.315ProLys: 2.315 ± 0.573
3.523ProLeu: 3.523 ± 0.629
1.007ProMet: 1.007 ± 0.419
2.919ProAsn: 2.919 ± 0.467
1.711ProPro: 1.711 ± 0.477
1.309ProGln: 1.309 ± 0.357
2.617ProArg: 2.617 ± 0.46
3.724ProSer: 3.724 ± 0.514
4.731ProThr: 4.731 ± 0.641
3.523ProVal: 3.523 ± 0.601
0.302ProTrp: 0.302 ± 0.164
2.214ProTyr: 2.214 ± 0.582
0.0ProXaa: 0.0 ± 0.0
Gln
2.718GlnAla: 2.718 ± 0.518
0.906GlnCys: 0.906 ± 0.435
1.61GlnAsp: 1.61 ± 0.515
2.013GlnGlu: 2.013 ± 0.434
1.812GlnPhe: 1.812 ± 0.348
1.409GlnGly: 1.409 ± 0.497
1.711GlnHis: 1.711 ± 0.415
3.221GlnIle: 3.221 ± 0.482
1.61GlnLys: 1.61 ± 0.514
4.127GlnLeu: 4.127 ± 0.68
0.705GlnMet: 0.705 ± 0.222
2.013GlnAsn: 2.013 ± 0.389
1.812GlnPro: 1.812 ± 0.437
2.013GlnGln: 2.013 ± 0.311
2.516GlnArg: 2.516 ± 0.707
3.523GlnSer: 3.523 ± 0.454
3.422GlnThr: 3.422 ± 0.601
2.315GlnVal: 2.315 ± 0.487
0.403GlnTrp: 0.403 ± 0.151
1.61GlnTyr: 1.61 ± 0.381
0.0GlnXaa: 0.0 ± 0.0
Arg
4.529ArgAla: 4.529 ± 0.594
1.007ArgCys: 1.007 ± 0.301
3.422ArgAsp: 3.422 ± 0.653
3.624ArgGlu: 3.624 ± 0.346
1.61ArgPhe: 1.61 ± 0.201
3.02ArgGly: 3.02 ± 0.521
1.812ArgHis: 1.812 ± 0.368
3.422ArgIle: 3.422 ± 0.415
2.214ArgLys: 2.214 ± 0.417
5.637ArgLeu: 5.637 ± 0.555
1.107ArgMet: 1.107 ± 0.297
3.523ArgAsn: 3.523 ± 0.471
1.912ArgPro: 1.912 ± 0.428
2.919ArgGln: 2.919 ± 0.732
3.926ArgArg: 3.926 ± 0.734
4.932ArgSer: 4.932 ± 0.682
4.63ArgThr: 4.63 ± 0.594
3.523ArgVal: 3.523 ± 0.609
0.705ArgTrp: 0.705 ± 0.181
3.322ArgTyr: 3.322 ± 0.563
0.0ArgXaa: 0.0 ± 0.0
Ser
3.825SerAla: 3.825 ± 0.745
0.705SerCys: 0.705 ± 0.235
4.328SerAsp: 4.328 ± 0.598
3.624SerGlu: 3.624 ± 0.612
2.214SerPhe: 2.214 ± 0.539
3.624SerGly: 3.624 ± 0.475
2.114SerHis: 2.114 ± 0.459
5.234SerIle: 5.234 ± 0.678
3.322SerLys: 3.322 ± 0.781
6.039SerLeu: 6.039 ± 0.685
1.51SerMet: 1.51 ± 0.255
3.724SerAsn: 3.724 ± 0.571
2.818SerPro: 2.818 ± 0.503
3.12SerGln: 3.12 ± 0.548
4.026SerArg: 4.026 ± 0.407
5.133SerSer: 5.133 ± 0.569
5.033SerThr: 5.033 ± 0.85
5.133SerVal: 5.133 ± 0.597
1.208SerTrp: 1.208 ± 0.317
2.516SerTyr: 2.516 ± 0.465
0.0SerXaa: 0.0 ± 0.0
Thr
3.624ThrAla: 3.624 ± 0.547
0.805ThrCys: 0.805 ± 0.255
3.422ThrAsp: 3.422 ± 0.545
4.227ThrGlu: 4.227 ± 0.747
3.523ThrPhe: 3.523 ± 0.666
2.516ThrGly: 2.516 ± 0.522
2.818ThrHis: 2.818 ± 0.677
4.731ThrIle: 4.731 ± 0.668
3.523ThrLys: 3.523 ± 0.785
6.744ThrLeu: 6.744 ± 0.872
2.114ThrMet: 2.114 ± 0.409
3.624ThrAsn: 3.624 ± 0.414
4.026ThrPro: 4.026 ± 0.521
2.114ThrGln: 2.114 ± 0.471
4.227ThrArg: 4.227 ± 0.604
4.731ThrSer: 4.731 ± 0.548
6.241ThrThr: 6.241 ± 0.848
4.429ThrVal: 4.429 ± 0.77
0.906ThrTrp: 0.906 ± 0.333
3.12ThrTyr: 3.12 ± 0.421
0.0ThrXaa: 0.0 ± 0.0
Val
2.919ValAla: 2.919 ± 0.421
0.604ValCys: 0.604 ± 0.187
2.718ValAsp: 2.718 ± 0.748
3.422ValGlu: 3.422 ± 0.468
2.718ValPhe: 2.718 ± 0.636
3.02ValGly: 3.02 ± 0.486
1.711ValHis: 1.711 ± 0.321
4.731ValIle: 4.731 ± 0.52
3.12ValLys: 3.12 ± 0.237
4.127ValLeu: 4.127 ± 0.544
1.711ValMet: 1.711 ± 0.311
4.026ValAsn: 4.026 ± 0.975
2.919ValPro: 2.919 ± 0.427
3.322ValGln: 3.322 ± 0.453
4.731ValArg: 4.731 ± 0.68
4.731ValSer: 4.731 ± 0.5
4.328ValThr: 4.328 ± 0.466
4.127ValVal: 4.127 ± 0.593
0.302ValTrp: 0.302 ± 0.161
2.315ValTyr: 2.315 ± 0.375
0.0ValXaa: 0.0 ± 0.0
Trp
0.403TrpAla: 0.403 ± 0.189
0.201TrpCys: 0.201 ± 0.124
0.705TrpAsp: 0.705 ± 0.223
0.302TrpGlu: 0.302 ± 0.156
0.101TrpPhe: 0.101 ± 0.101
0.503TrpGly: 0.503 ± 0.189
0.101TrpHis: 0.101 ± 0.08
0.302TrpIle: 0.302 ± 0.159
0.805TrpLys: 0.805 ± 0.221
0.906TrpLeu: 0.906 ± 0.3
0.201TrpMet: 0.201 ± 0.138
0.805TrpAsn: 0.805 ± 0.336
0.201TrpPro: 0.201 ± 0.117
0.705TrpGln: 0.705 ± 0.275
0.906TrpArg: 0.906 ± 0.318
0.705TrpSer: 0.705 ± 0.274
0.302TrpThr: 0.302 ± 0.137
0.302TrpVal: 0.302 ± 0.282
0.0TrpTrp: 0.0 ± 0.0
0.503TrpTyr: 0.503 ± 0.187
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.416TyrAla: 2.416 ± 0.544
0.503TyrCys: 0.503 ± 0.231
3.12TyrAsp: 3.12 ± 0.459
2.516TyrGlu: 2.516 ± 0.383
1.208TyrPhe: 1.208 ± 0.293
2.718TyrGly: 2.718 ± 0.385
1.51TyrHis: 1.51 ± 0.335
3.926TyrIle: 3.926 ± 0.584
2.516TyrLys: 2.516 ± 0.391
4.529TyrLeu: 4.529 ± 0.94
1.107TyrMet: 1.107 ± 0.248
2.114TyrAsn: 2.114 ± 0.296
2.516TyrPro: 2.516 ± 0.571
2.114TyrGln: 2.114 ± 0.468
1.912TyrArg: 1.912 ± 0.487
2.214TyrSer: 2.214 ± 0.406
2.214TyrThr: 2.214 ± 0.484
2.617TyrVal: 2.617 ± 0.42
0.201TyrTrp: 0.201 ± 0.137
1.208TyrTyr: 1.208 ± 0.33
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 16 proteins (9936 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski