Amino acid dipepetide frequency for Acinetobacter stercoris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.696AlaAla: 6.696 ± 0.122	0.92AlaCys: 0.92 ± 0.028	4.155AlaAsp: 4.155 ± 0.075	5.033AlaGlu: 5.033 ± 0.087	3.312AlaPhe: 3.312 ± 0.053	5.783AlaGly: 5.783 ± 0.1	1.686AlaHis: 1.686 ± 0.044	5.945AlaIle: 5.945 ± 0.074	5.082AlaLys: 5.082 ± 0.087	8.813AlaLeu: 8.813 ± 0.109	2.242AlaMet: 2.242 ± 0.05	3.466AlaAsn: 3.466 ± 0.067	2.772AlaPro: 2.772 ± 0.057	3.788AlaGln: 3.788 ± 0.069	3.219AlaArg: 3.219 ± 0.058	4.778AlaSer: 4.778 ± 0.072	4.387AlaThr: 4.387 ± 0.066	5.257AlaVal: 5.257 ± 0.072	1.05AlaTrp: 1.05 ± 0.033	2.633AlaTyr: 2.633 ± 0.052	0.007AlaXaa: 0.007 ± 0.003
Cys	0.654CysAla: 0.654 ± 0.027	0.142CysCys: 0.142 ± 0.01	0.461CysAsp: 0.461 ± 0.021	0.492CysGlu: 0.492 ± 0.021	0.469CysPhe: 0.469 ± 0.022	0.784CysGly: 0.784 ± 0.028	0.265CysHis: 0.265 ± 0.014	0.719CysIle: 0.719 ± 0.028	0.434CysLys: 0.434 ± 0.019	0.992CysLeu: 0.992 ± 0.029	0.235CysMet: 0.235 ± 0.015	0.33CysAsn: 0.33 ± 0.015	0.432CysPro: 0.432 ± 0.02	0.41CysGln: 0.41 ± 0.021	0.409CysArg: 0.409 ± 0.017	0.621CysSer: 0.621 ± 0.021	0.418CysThr: 0.418 ± 0.021	0.57CysVal: 0.57 ± 0.022	0.089CysTrp: 0.089 ± 0.009	0.303CysTyr: 0.303 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.314AspAla: 4.314 ± 0.071	0.391AspCys: 0.391 ± 0.021	2.701AspAsp: 2.701 ± 0.055	3.572AspGlu: 3.572 ± 0.067	2.554AspPhe: 2.554 ± 0.049	3.386AspGly: 3.386 ± 0.077	1.365AspHis: 1.365 ± 0.033	3.983AspIle: 3.983 ± 0.061	2.824AspLys: 2.824 ± 0.05	5.688AspLeu: 5.688 ± 0.086	1.178AspMet: 1.178 ± 0.034	2.02AspAsn: 2.02 ± 0.051	2.093AspPro: 2.093 ± 0.046	2.98AspGln: 2.98 ± 0.059	2.23AspArg: 2.23 ± 0.045	3.112AspSer: 3.112 ± 0.299	2.509AspThr: 2.509 ± 0.056	3.606AspVal: 3.606 ± 0.055	0.812AspTrp: 0.812 ± 0.027	1.998AspTyr: 1.998 ± 0.04	0.003AspXaa: 0.003 ± 0.002
Glu	4.37GluAla: 4.37 ± 0.073	0.382GluCys: 0.382 ± 0.016	2.641GluAsp: 2.641 ± 0.054	2.99GluGlu: 2.99 ± 0.056	2.307GluPhe: 2.307 ± 0.049	2.936GluGly: 2.936 ± 0.058	1.651GluHis: 1.651 ± 0.045	4.533GluIle: 4.533 ± 0.071	4.307GluLys: 4.307 ± 0.062	5.97GluLeu: 5.97 ± 0.077	1.431GluMet: 1.431 ± 0.036	3.464GluAsn: 3.464 ± 0.051	1.763GluPro: 1.763 ± 0.042	3.84GluGln: 3.84 ± 0.069	2.763GluArg: 2.763 ± 0.055	3.146GluSer: 3.146 ± 0.055	3.03GluThr: 3.03 ± 0.065	3.552GluVal: 3.552 ± 0.063	0.778GluTrp: 0.778 ± 0.025	1.972GluTyr: 1.972 ± 0.048	0.001GluXaa: 0.001 ± 0.001
Phe	3.595PheAla: 3.595 ± 0.059	0.503PheCys: 0.503 ± 0.022	2.666PheAsp: 2.666 ± 0.051	2.537PheGlu: 2.537 ± 0.057	2.017PhePhe: 2.017 ± 0.052	3.198PheGly: 3.198 ± 0.057	0.862PheHis: 0.862 ± 0.028	3.411PheIle: 3.411 ± 0.062	2.735PheLys: 2.735 ± 0.054	4.018PheLeu: 4.018 ± 0.069	1.078PheMet: 1.078 ± 0.029	2.306PheAsn: 2.306 ± 0.043	1.56PhePro: 1.56 ± 0.037	1.632PheGln: 1.632 ± 0.041	1.421PheArg: 1.421 ± 0.038	3.268PheSer: 3.268 ± 0.058	2.235PheThr: 2.235 ± 0.045	2.605PheVal: 2.605 ± 0.051	0.623PheTrp: 0.623 ± 0.025	1.563PheTyr: 1.563 ± 0.04	0.003PheXaa: 0.003 ± 0.002
Gly	4.957GlyAla: 4.957 ± 0.082	0.762GlyCys: 0.762 ± 0.026	3.042GlyAsp: 3.042 ± 0.06	3.526GlyGlu: 3.526 ± 0.062	3.331GlyPhe: 3.331 ± 0.062	4.635GlyGly: 4.635 ± 0.103	1.606GlyHis: 1.606 ± 0.042	5.021GlyIle: 5.021 ± 0.069	3.822GlyLys: 3.822 ± 0.064	7.011GlyLeu: 7.011 ± 0.092	1.774GlyMet: 1.774 ± 0.044	2.723GlyAsn: 2.723 ± 0.076	1.428GlyPro: 1.428 ± 0.041	3.134GlyGln: 3.134 ± 0.069	2.708GlyArg: 2.708 ± 0.05	3.987GlySer: 3.987 ± 0.073	3.637GlyThr: 3.637 ± 0.084	4.697GlyVal: 4.697 ± 0.077	0.936GlyTrp: 0.936 ± 0.031	2.549GlyTyr: 2.549 ± 0.044	0.003GlyXaa: 0.003 ± 0.002
His	1.872HisAla: 1.872 ± 0.045	0.24HisCys: 0.24 ± 0.013	1.272HisAsp: 1.272 ± 0.038	1.22HisGlu: 1.22 ± 0.037	1.295HisPhe: 1.295 ± 0.036	1.54HisGly: 1.54 ± 0.042	0.817HisHis: 0.817 ± 0.028	1.711HisIle: 1.711 ± 0.039	1.06HisLys: 1.06 ± 0.031	2.469HisLeu: 2.469 ± 0.054	0.563HisMet: 0.563 ± 0.022	0.863HisAsn: 0.863 ± 0.026	1.322HisPro: 1.322 ± 0.036	1.252HisGln: 1.252 ± 0.035	0.995HisArg: 0.995 ± 0.029	1.353HisSer: 1.353 ± 0.031	1.14HisThr: 1.14 ± 0.033	1.416HisVal: 1.416 ± 0.032	0.376HisTrp: 0.376 ± 0.018	0.948HisTyr: 0.948 ± 0.027	0.005HisXaa: 0.005 ± 0.002
Ile	6.462IleAla: 6.462 ± 0.087	0.818IleCys: 0.818 ± 0.027	4.387IleAsp: 4.387 ± 0.067	4.734IleGlu: 4.734 ± 0.069	3.14IlePhe: 3.14 ± 0.061	5.117IleGly: 5.117 ± 0.091	1.626IleHis: 1.626 ± 0.035	4.829IleIle: 4.829 ± 0.076	3.879IleLys: 3.879 ± 0.06	6.904IleLeu: 6.904 ± 0.095	1.47IleMet: 1.47 ± 0.036	3.369IleAsn: 3.369 ± 0.064	3.218IlePro: 3.218 ± 0.052	3.787IleGln: 3.787 ± 0.067	3.084IleArg: 3.084 ± 0.051	5.035IleSer: 5.035 ± 0.082	3.768IleThr: 3.768 ± 0.076	4.393IleVal: 4.393 ± 0.074	0.8IleTrp: 0.8 ± 0.028	2.311IleTyr: 2.311 ± 0.052	0.008IleXaa: 0.008 ± 0.003
Lys	4.934LysAla: 4.934 ± 0.083	0.329LysCys: 0.329 ± 0.017	3.256LysAsp: 3.256 ± 0.054	3.297LysGlu: 3.297 ± 0.055	2.13LysPhe: 2.13 ± 0.045	3.214LysGly: 3.214 ± 0.062	1.358LysHis: 1.358 ± 0.037	4.544LysIle: 4.544 ± 0.064	3.94LysLys: 3.94 ± 0.068	5.629LysLeu: 5.629 ± 0.072	1.588LysMet: 1.588 ± 0.036	3.526LysAsn: 3.526 ± 0.059	2.335LysPro: 2.335 ± 0.049	3.393LysGln: 3.393 ± 0.067	2.546LysArg: 2.546 ± 0.045	3.52LysSer: 3.52 ± 0.061	3.535LysThr: 3.535 ± 0.058	3.929LysVal: 3.929 ± 0.055	0.664LysTrp: 0.664 ± 0.028	2.013LysTyr: 2.013 ± 0.045	0.01LysXaa: 0.01 ± 0.003
Leu	8.685LeuAla: 8.685 ± 0.112	1.052LeuCys: 1.052 ± 0.033	5.72LeuAsp: 5.72 ± 0.071	5.817LeuGlu: 5.817 ± 0.079	4.29LeuPhe: 4.29 ± 0.077	6.989LeuGly: 6.989 ± 0.104	2.077LeuHis: 2.077 ± 0.047	7.195LeuIle: 7.195 ± 0.093	6.833LeuLys: 6.833 ± 0.078	9.49LeuLeu: 9.49 ± 0.139	2.39LeuMet: 2.39 ± 0.045	5.582LeuAsn: 5.582 ± 0.075	4.367LeuPro: 4.367 ± 0.069	4.174LeuGln: 4.174 ± 0.072	3.861LeuArg: 3.861 ± 0.061	7.446LeuSer: 7.446 ± 0.085	5.656LeuThr: 5.656 ± 0.067	6.09LeuVal: 6.09 ± 0.07	1.151LeuTrp: 1.151 ± 0.034	2.844LeuTyr: 2.844 ± 0.051	0.011LeuXaa: 0.011 ± 0.004
Met	1.951MetAla: 1.951 ± 0.045	0.194MetCys: 0.194 ± 0.012	1.072MetAsp: 1.072 ± 0.031	0.885MetGlu: 0.885 ± 0.025	0.905MetPhe: 0.905 ± 0.03	1.603MetGly: 1.603 ± 0.037	0.557MetHis: 0.557 ± 0.02	1.695MetIle: 1.695 ± 0.042	1.516MetLys: 1.516 ± 0.039	2.435MetLeu: 2.435 ± 0.057	0.693MetMet: 0.693 ± 0.024	1.36MetAsn: 1.36 ± 0.037	1.102MetPro: 1.102 ± 0.034	1.389MetGln: 1.389 ± 0.039	1.022MetArg: 1.022 ± 0.032	1.887MetSer: 1.887 ± 0.039	1.513MetThr: 1.513 ± 0.038	1.47MetVal: 1.47 ± 0.039	0.212MetTrp: 0.212 ± 0.012	0.585MetTyr: 0.585 ± 0.023	0.003MetXaa: 0.003 ± 0.001
Asn	3.804AsnAla: 3.804 ± 0.068	0.387AsnCys: 0.387 ± 0.018	2.473AsnAsp: 2.473 ± 0.05	2.519AsnGlu: 2.519 ± 0.052	2.026AsnPhe: 2.026 ± 0.046	3.071AsnGly: 3.071 ± 0.07	1.12AsnHis: 1.12 ± 0.034	3.804AsnIle: 3.804 ± 0.067	2.747AsnLys: 2.747 ± 0.057	4.647AsnLeu: 4.647 ± 0.072	1.082AsnMet: 1.082 ± 0.031	2.495AsnAsn: 2.495 ± 0.077	2.439AsnPro: 2.439 ± 0.047	2.65AsnGln: 2.65 ± 0.06	1.874AsnArg: 1.874 ± 0.038	2.855AsnSer: 2.855 ± 0.067	2.727AsnThr: 2.727 ± 0.063	2.973AsnVal: 2.973 ± 0.053	0.655AsnTrp: 0.655 ± 0.023	1.694AsnTyr: 1.694 ± 0.041	0.003AsnXaa: 0.003 ± 0.002
Pro	3.06ProAla: 3.06 ± 0.053	0.257ProCys: 0.257 ± 0.013	2.424ProAsp: 2.424 ± 0.044	3.324ProGlu: 3.324 ± 0.06	1.79ProPhe: 1.79 ± 0.039	1.663ProGly: 1.663 ± 0.04	0.902ProHis: 0.902 ± 0.031	2.65ProIle: 2.65 ± 0.049	2.464ProLys: 2.464 ± 0.045	3.841ProLeu: 3.841 ± 0.071	0.882ProMet: 0.882 ± 0.026	2.039ProAsn: 2.039 ± 0.052	1.107ProPro: 1.107 ± 0.037	1.678ProGln: 1.678 ± 0.045	1.336ProArg: 1.336 ± 0.042	2.317ProSer: 2.317 ± 0.053	2.162ProThr: 2.162 ± 0.052	3.108ProVal: 3.108 ± 0.058	0.467ProTrp: 0.467 ± 0.021	1.439ProTyr: 1.439 ± 0.032	0.002ProXaa: 0.002 ± 0.001
Gln	4.311GlnAla: 4.311 ± 0.072	0.377GlnCys: 0.377 ± 0.017	2.414GlnAsp: 2.414 ± 0.048	2.568GlnGlu: 2.568 ± 0.05	1.993GlnPhe: 1.993 ± 0.045	3.023GlnGly: 3.023 ± 0.065	1.479GlnHis: 1.479 ± 0.042	3.699GlnIle: 3.699 ± 0.056	3.206GlnLys: 3.206 ± 0.067	5.203GlnLeu: 5.203 ± 0.077	1.163GlnMet: 1.163 ± 0.033	2.607GlnAsn: 2.607 ± 0.057	1.854GlnPro: 1.854 ± 0.044	3.248GlnGln: 3.248 ± 0.079	2.123GlnArg: 2.123 ± 0.043	3.064GlnSer: 3.064 ± 0.064	2.563GlnThr: 2.563 ± 0.055	3.191GlnVal: 3.191 ± 0.058	0.642GlnTrp: 0.642 ± 0.024	1.865GlnTyr: 1.865 ± 0.047	0.003GlnXaa: 0.003 ± 0.002
Arg	2.943ArgAla: 2.943 ± 0.052	0.325ArgCys: 0.325 ± 0.015	2.095ArgAsp: 2.095 ± 0.044	2.548ArgGlu: 2.548 ± 0.05	2.092ArgPhe: 2.092 ± 0.045	2.321ArgGly: 2.321 ± 0.049	1.055ArgHis: 1.055 ± 0.032	3.053ArgIle: 3.053 ± 0.055	2.409ArgLys: 2.409 ± 0.042	4.472ArgLeu: 4.472 ± 0.067	1.057ArgMet: 1.057 ± 0.033	1.824ArgAsn: 1.824 ± 0.043	1.582ArgPro: 1.582 ± 0.04	2.138ArgGln: 2.138 ± 0.048	1.888ArgArg: 1.888 ± 0.051	2.345ArgSer: 2.345 ± 0.049	1.946ArgThr: 1.946 ± 0.042	2.673ArgVal: 2.673 ± 0.052	0.496ArgTrp: 0.496 ± 0.017	1.704ArgTyr: 1.704 ± 0.039	0.001ArgXaa: 0.001 ± 0.001
Ser	4.799SerAla: 4.799 ± 0.065	0.518SerCys: 0.518 ± 0.021	3.559SerAsp: 3.559 ± 0.292	3.566SerGlu: 3.566 ± 0.064	2.963SerPhe: 2.963 ± 0.053	4.572SerGly: 4.572 ± 0.08	1.531SerHis: 1.531 ± 0.041	4.786SerIle: 4.786 ± 0.073	3.655SerLys: 3.655 ± 0.063	6.544SerLeu: 6.544 ± 0.082	1.513SerMet: 1.513 ± 0.041	3.016SerAsn: 3.016 ± 0.069	2.394SerPro: 2.394 ± 0.046	2.962SerGln: 2.962 ± 0.065	2.541SerArg: 2.541 ± 0.046	4.393SerSer: 4.393 ± 0.08	3.474SerThr: 3.474 ± 0.062	3.981SerVal: 3.981 ± 0.078	0.721SerTrp: 0.721 ± 0.025	2.175SerTyr: 2.175 ± 0.049	0.007SerXaa: 0.007 ± 0.003
Thr	4.619ThrAla: 4.619 ± 0.087	0.464ThrCys: 0.464 ± 0.018	2.878ThrAsp: 2.878 ± 0.072	3.051ThrGlu: 3.051 ± 0.046	2.163ThrPhe: 2.163 ± 0.046	4.237ThrGly: 4.237 ± 0.076	1.293ThrHis: 1.293 ± 0.034	3.542ThrIle: 3.542 ± 0.055	2.481ThrLys: 2.481 ± 0.047	5.797ThrLeu: 5.797 ± 0.078	1.022ThrMet: 1.022 ± 0.031	2.084ThrAsn: 2.084 ± 0.053	2.767ThrPro: 2.767 ± 0.067	2.622ThrGln: 2.622 ± 0.051	2.175ThrArg: 2.175 ± 0.042	3.301ThrSer: 3.301 ± 0.058	3.218ThrThr: 3.218 ± 0.086	3.801ThrVal: 3.801 ± 0.091	0.667ThrTrp: 0.667 ± 0.026	1.659ThrTyr: 1.659 ± 0.036	0.014ThrXaa: 0.014 ± 0.01
Val	5.415ValAla: 5.415 ± 0.071	0.672ValCys: 0.672 ± 0.023	3.644ValAsp: 3.644 ± 0.072	3.983ValGlu: 3.983 ± 0.071	2.752ValPhe: 2.752 ± 0.054	4.257ValGly: 4.257 ± 0.065	1.31ValHis: 1.31 ± 0.032	4.905ValIle: 4.905 ± 0.077	3.665ValLys: 3.665 ± 0.062	6.529ValLeu: 6.529 ± 0.079	1.635ValMet: 1.635 ± 0.043	2.995ValAsn: 2.995 ± 0.059	2.571ValPro: 2.571 ± 0.05	2.759ValGln: 2.759 ± 0.05	2.557ValArg: 2.557 ± 0.051	4.202ValSer: 4.202 ± 0.062	3.615ValThr: 3.615 ± 0.07	4.554ValVal: 4.554 ± 0.076	0.806ValTrp: 0.806 ± 0.026	1.899ValTyr: 1.899 ± 0.038	0.003ValXaa: 0.003 ± 0.002
Trp	0.842TrpAla: 0.842 ± 0.032	0.141TrpCys: 0.141 ± 0.012	0.608TrpAsp: 0.608 ± 0.022	0.503TrpGlu: 0.503 ± 0.021	0.64TrpPhe: 0.64 ± 0.025	0.757TrpGly: 0.757 ± 0.026	0.338TrpHis: 0.338 ± 0.019	0.984TrpIle: 0.984 ± 0.029	0.778TrpLys: 0.778 ± 0.026	1.581TrpLeu: 1.581 ± 0.042	0.397TrpMet: 0.397 ± 0.02	0.591TrpAsn: 0.591 ± 0.026	0.32TrpPro: 0.32 ± 0.016	0.739TrpGln: 0.739 ± 0.028	0.566TrpArg: 0.566 ± 0.025	0.8TrpSer: 0.8 ± 0.03	0.595TrpThr: 0.595 ± 0.024	0.851TrpVal: 0.851 ± 0.031	0.158TrpTrp: 0.158 ± 0.012	0.415TrpTyr: 0.415 ± 0.02	0.001TrpXaa: 0.001 ± 0.001
Tyr	2.741TyrAla: 2.741 ± 0.043	0.354TyrCys: 0.354 ± 0.017	1.847TyrAsp: 1.847 ± 0.049	1.663TyrGlu: 1.663 ± 0.037	1.664TyrPhe: 1.664 ± 0.039	2.202TyrGly: 2.202 ± 0.045	0.828TyrHis: 0.828 ± 0.03	2.114TyrIle: 2.114 ± 0.047	1.847TyrLys: 1.847 ± 0.042	3.678TyrLeu: 3.678 ± 0.067	0.654TyrMet: 0.654 ± 0.026	1.383TyrAsn: 1.383 ± 0.039	1.479TyrPro: 1.479 ± 0.04	2.017TyrGln: 2.017 ± 0.043	1.646TyrArg: 1.646 ± 0.038	2.237TyrSer: 2.237 ± 0.05	1.711TyrThr: 1.711 ± 0.049	2.007TyrVal: 2.007 ± 0.044	0.503TyrTrp: 0.503 ± 0.023	1.102TyrTyr: 1.102 ± 0.036	0.001TyrXaa: 0.001 ± 0.001
Xaa	0.003XaaAla: 0.003 ± 0.002	0.0XaaCys: 0.0 ± 0.0	0.002XaaAsp: 0.002 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.003XaaPhe: 0.003 ± 0.002	0.005XaaGly: 0.005 ± 0.002	0.003XaaHis: 0.003 ± 0.002	0.012XaaIle: 0.012 ± 0.004	0.007XaaLys: 0.007 ± 0.003	0.007XaaLeu: 0.007 ± 0.003	0.002XaaMet: 0.002 ± 0.001	0.004XaaAsn: 0.004 ± 0.002	0.005XaaPro: 0.005 ± 0.002	0.004XaaGln: 0.004 ± 0.002	0.004XaaArg: 0.004 ± 0.002	0.003XaaSer: 0.003 ± 0.002	0.013XaaThr: 0.013 ± 0.007	0.005XaaVal: 0.005 ± 0.002	0.001XaaTrp: 0.001 ± 0.001	0.007XaaTyr: 0.007 ± 0.003	0.008XaaXaa: 0.008 ± 0.005

Statistics based on 3857 proteins (1176768 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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