Amino acid dipepetide frequency for Alternaria alternata chrysovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.766AlaAla: 15.766 ± 0.799
1.689AlaCys: 1.689 ± 0.974
5.068AlaAsp: 5.068 ± 0.546
5.912AlaGlu: 5.912 ± 1.497
3.097AlaPhe: 3.097 ± 1.063
10.135AlaGly: 10.135 ± 2.435
0.563AlaHis: 0.563 ± 0.541
3.378AlaIle: 3.378 ± 0.71
5.068AlaLys: 5.068 ± 1.029
13.514AlaLeu: 13.514 ± 2.119
3.941AlaMet: 3.941 ± 0.57
3.378AlaAsn: 3.378 ± 0.657
6.475AlaPro: 6.475 ± 1.18
3.941AlaGln: 3.941 ± 1.472
9.854AlaArg: 9.854 ± 1.042
11.543AlaSer: 11.543 ± 1.451
7.883AlaThr: 7.883 ± 2.044
9.291AlaVal: 9.291 ± 1.583
0.845AlaTrp: 0.845 ± 0.656
3.378AlaTyr: 3.378 ± 0.788
0.0AlaXaa: 0.0 ± 0.0
Cys
1.971CysAla: 1.971 ± 0.364
0.282CysCys: 0.282 ± 0.212
0.563CysAsp: 0.563 ± 0.535
0.563CysGlu: 0.563 ± 0.327
0.0CysPhe: 0.0 ± 0.0
1.408CysGly: 1.408 ± 0.136
0.563CysHis: 0.563 ± 0.278
0.282CysIle: 0.282 ± 0.212
0.0CysLys: 0.0 ± 0.0
1.126CysLeu: 1.126 ± 1.069
0.282CysMet: 0.282 ± 0.271
1.408CysAsn: 1.408 ± 0.489
0.282CysPro: 0.282 ± 0.262
0.282CysGln: 0.282 ± 0.212
1.408CysArg: 1.408 ± 0.537
1.408CysSer: 1.408 ± 0.643
0.845CysThr: 0.845 ± 0.425
0.845CysVal: 0.845 ± 0.731
0.282CysTrp: 0.282 ± 0.262
0.282CysTyr: 0.282 ± 0.271
0.0CysXaa: 0.0 ± 0.0
Asp
4.223AspAla: 4.223 ± 0.915
1.689AspCys: 1.689 ± 0.273
1.971AspAsp: 1.971 ± 0.965
3.097AspGlu: 3.097 ± 0.717
0.845AspPhe: 0.845 ± 0.812
4.505AspGly: 4.505 ± 0.45
0.282AspHis: 0.282 ± 0.212
1.126AspIle: 1.126 ± 0.448
0.563AspLys: 0.563 ± 0.278
5.068AspLeu: 5.068 ± 1.236
1.126AspMet: 1.126 ± 0.462
1.971AspAsn: 1.971 ± 0.631
3.378AspPro: 3.378 ± 1.519
2.534AspGln: 2.534 ± 0.883
1.689AspArg: 1.689 ± 0.526
2.252AspSer: 2.252 ± 0.68
2.815AspThr: 2.815 ± 0.522
3.66AspVal: 3.66 ± 1.204
1.408AspTrp: 1.408 ± 0.638
2.815AspTyr: 2.815 ± 0.528
0.0AspXaa: 0.0 ± 0.0
Glu
8.164GluAla: 8.164 ± 0.776
1.126GluCys: 1.126 ± 0.532
2.534GluAsp: 2.534 ± 0.875
7.883GluGlu: 7.883 ± 1.835
2.252GluPhe: 2.252 ± 0.908
3.378GluGly: 3.378 ± 0.585
1.126GluHis: 1.126 ± 0.313
0.845GluIle: 0.845 ± 0.469
1.689GluLys: 1.689 ± 0.679
6.757GluLeu: 6.757 ± 1.567
1.971GluMet: 1.971 ± 0.704
0.282GluAsn: 0.282 ± 0.271
2.815GluPro: 2.815 ± 0.781
4.786GluGln: 4.786 ± 0.348
3.941GluArg: 3.941 ± 0.951
3.097GluSer: 3.097 ± 0.919
1.408GluThr: 1.408 ± 0.689
7.038GluVal: 7.038 ± 0.799
1.408GluTrp: 1.408 ± 0.489
1.971GluTyr: 1.971 ± 1.19
0.0GluXaa: 0.0 ± 0.0
Phe
1.971PheAla: 1.971 ± 0.555
0.0PheCys: 0.0 ± 0.0
0.845PheAsp: 0.845 ± 0.419
1.408PheGlu: 1.408 ± 0.489
1.408PhePhe: 1.408 ± 0.136
2.252PheGly: 2.252 ± 1.01
0.282PheHis: 0.282 ± 0.271
0.845PheIle: 0.845 ± 0.239
1.408PheLys: 1.408 ± 0.136
2.534PheLeu: 2.534 ± 0.756
0.563PheMet: 0.563 ± 0.425
0.563PheAsn: 0.563 ± 0.278
1.126PhePro: 1.126 ± 0.604
0.563PheGln: 0.563 ± 0.286
2.815PheArg: 2.815 ± 0.272
1.971PheSer: 1.971 ± 0.287
0.845PheThr: 0.845 ± 0.251
2.252PheVal: 2.252 ± 0.321
0.845PheTrp: 0.845 ± 0.656
0.845PheTyr: 0.845 ± 0.37
0.0PheXaa: 0.0 ± 0.0
Gly
10.698GlyAla: 10.698 ± 1.234
0.845GlyCys: 0.845 ± 0.251
4.505GlyAsp: 4.505 ± 1.207
3.941GlyGlu: 3.941 ± 1.44
2.815GlyPhe: 2.815 ± 0.475
6.475GlyGly: 6.475 ± 1.427
0.845GlyHis: 0.845 ± 0.251
1.971GlyIle: 1.971 ± 0.364
2.252GlyLys: 2.252 ± 0.531
8.446GlyLeu: 8.446 ± 1.299
1.126GlyMet: 1.126 ± 0.38
1.126GlyAsn: 1.126 ± 0.452
5.068GlyPro: 5.068 ± 1.106
2.252GlyGln: 2.252 ± 1.136
4.505GlyArg: 4.505 ± 0.839
4.223GlySer: 4.223 ± 0.741
2.815GlyThr: 2.815 ± 1.018
8.164GlyVal: 8.164 ± 1.579
0.845GlyTrp: 0.845 ± 0.535
2.252GlyTyr: 2.252 ± 0.904
0.0GlyXaa: 0.0 ± 0.0
His
3.097HisAla: 3.097 ± 0.336
0.0HisCys: 0.0 ± 0.0
0.845HisAsp: 0.845 ± 0.239
1.971HisGlu: 1.971 ± 0.926
0.282HisPhe: 0.282 ± 0.271
2.534HisGly: 2.534 ± 0.985
1.689HisHis: 1.689 ± 0.948
0.282HisIle: 0.282 ± 0.212
0.282HisLys: 0.282 ± 0.212
2.252HisLeu: 2.252 ± 1.065
0.282HisMet: 0.282 ± 0.212
0.563HisAsn: 0.563 ± 0.343
0.563HisPro: 0.563 ± 0.278
0.845HisGln: 0.845 ± 0.496
1.408HisArg: 1.408 ± 0.136
1.689HisSer: 1.689 ± 0.336
1.408HisThr: 1.408 ± 0.64
1.971HisVal: 1.971 ± 0.768
0.563HisTrp: 0.563 ± 0.286
0.845HisTyr: 0.845 ± 0.419
0.0HisXaa: 0.0 ± 0.0
Ile
3.66IleAla: 3.66 ± 0.78
0.563IleCys: 0.563 ± 0.535
0.845IleAsp: 0.845 ± 0.318
2.252IleGlu: 2.252 ± 0.825
0.282IlePhe: 0.282 ± 0.271
1.126IleGly: 1.126 ± 0.354
0.563IleHis: 0.563 ± 0.286
0.563IleIle: 0.563 ± 0.245
0.282IleLys: 0.282 ± 0.262
1.971IleLeu: 1.971 ± 0.514
0.282IleMet: 0.282 ± 0.212
0.282IleAsn: 0.282 ± 0.212
1.689IlePro: 1.689 ± 0.502
0.282IleGln: 0.282 ± 0.27
1.971IleArg: 1.971 ± 0.694
1.971IleSer: 1.971 ± 0.521
1.689IleThr: 1.689 ± 0.957
1.689IleVal: 1.689 ± 0.68
0.282IleTrp: 0.282 ± 0.482
0.282IleTyr: 0.282 ± 0.262
0.0IleXaa: 0.0 ± 0.0
Lys
4.505LysAla: 4.505 ± 1.512
0.845LysCys: 0.845 ± 0.496
1.408LysAsp: 1.408 ± 0.513
1.971LysGlu: 1.971 ± 0.872
0.845LysPhe: 0.845 ± 0.239
1.689LysGly: 1.689 ± 0.801
0.845LysHis: 0.845 ± 0.239
0.282LysIle: 0.282 ± 0.271
0.0LysLys: 0.0 ± 0.0
3.378LysLeu: 3.378 ± 0.867
1.689LysMet: 1.689 ± 0.547
0.0LysAsn: 0.0 ± 0.0
2.815LysPro: 2.815 ± 0.954
0.845LysGln: 0.845 ± 0.419
1.971LysArg: 1.971 ± 0.573
3.097LysSer: 3.097 ± 1.323
0.563LysThr: 0.563 ± 0.302
2.534LysVal: 2.534 ± 1.268
0.563LysTrp: 0.563 ± 0.425
1.126LysTyr: 1.126 ± 0.85
0.0LysXaa: 0.0 ± 0.0
Leu
11.824LeuAla: 11.824 ± 2.216
2.252LeuCys: 2.252 ± 0.79
6.194LeuAsp: 6.194 ± 0.909
4.786LeuGlu: 4.786 ± 0.586
2.534LeuPhe: 2.534 ± 0.72
9.009LeuGly: 9.009 ± 0.676
2.815LeuHis: 2.815 ± 1.036
1.971LeuIle: 1.971 ± 0.654
2.815LeuLys: 2.815 ± 0.905
11.824LeuLeu: 11.824 ± 2.131
2.534LeuMet: 2.534 ± 0.467
1.126LeuAsn: 1.126 ± 0.571
5.631LeuPro: 5.631 ± 1.317
4.505LeuGln: 4.505 ± 0.982
8.164LeuArg: 8.164 ± 1.658
9.291LeuSer: 9.291 ± 1.374
6.194LeuThr: 6.194 ± 0.54
8.727LeuVal: 8.727 ± 1.127
1.408LeuTrp: 1.408 ± 0.478
3.097LeuTyr: 3.097 ± 0.777
0.0LeuXaa: 0.0 ± 0.0
Met
2.252MetAla: 2.252 ± 0.302
0.282MetCys: 0.282 ± 0.212
1.126MetAsp: 1.126 ± 0.426
1.408MetGlu: 1.408 ± 0.591
0.845MetPhe: 0.845 ± 0.656
2.815MetGly: 2.815 ± 0.676
1.126MetHis: 1.126 ± 0.489
0.563MetIle: 0.563 ± 0.541
1.126MetLys: 1.126 ± 0.466
3.097MetLeu: 3.097 ± 0.282
1.689MetMet: 1.689 ± 0.822
0.282MetAsn: 0.282 ± 0.212
0.845MetPro: 0.845 ± 0.786
1.126MetGln: 1.126 ± 0.329
2.252MetArg: 2.252 ± 0.488
1.126MetSer: 1.126 ± 0.121
1.126MetThr: 1.126 ± 0.552
1.971MetVal: 1.971 ± 0.287
0.282MetTrp: 0.282 ± 0.271
0.563MetTyr: 0.563 ± 0.327
0.0MetXaa: 0.0 ± 0.0
Asn
1.971AsnAla: 1.971 ± 0.273
0.0AsnCys: 0.0 ± 0.0
1.408AsnAsp: 1.408 ± 0.805
1.126AsnGlu: 1.126 ± 0.422
0.845AsnPhe: 0.845 ± 0.55
1.126AsnGly: 1.126 ± 0.654
0.563AsnHis: 0.563 ± 0.245
0.563AsnIle: 0.563 ± 0.245
0.845AsnLys: 0.845 ± 0.656
3.378AsnLeu: 3.378 ± 0.574
0.282AsnMet: 0.282 ± 0.262
0.0AsnAsn: 0.0 ± 0.0
1.971AsnPro: 1.971 ± 0.65
0.282AsnGln: 0.282 ± 0.262
0.282AsnArg: 0.282 ± 0.212
2.534AsnSer: 2.534 ± 0.459
1.408AsnThr: 1.408 ± 0.466
0.845AsnVal: 0.845 ± 0.425
0.0AsnTrp: 0.0 ± 0.0
1.408AsnTyr: 1.408 ± 0.701
0.0AsnXaa: 0.0 ± 0.0
Pro
7.883ProAla: 7.883 ± 1.025
0.845ProCys: 0.845 ± 0.37
2.534ProAsp: 2.534 ± 0.381
4.505ProGlu: 4.505 ± 0.908
0.845ProPhe: 0.845 ± 0.547
5.068ProGly: 5.068 ± 1.958
0.845ProHis: 0.845 ± 0.496
1.971ProIle: 1.971 ± 0.9
2.815ProLys: 2.815 ± 0.873
4.223ProLeu: 4.223 ± 0.344
0.563ProMet: 0.563 ± 0.245
2.815ProAsn: 2.815 ± 0.877
2.534ProPro: 2.534 ± 1.642
2.534ProGln: 2.534 ± 0.448
2.815ProArg: 2.815 ± 0.895
3.66ProSer: 3.66 ± 1.312
3.941ProThr: 3.941 ± 0.824
2.815ProVal: 2.815 ± 1.196
0.563ProTrp: 0.563 ± 0.484
1.689ProTyr: 1.689 ± 1.029
0.0ProXaa: 0.0 ± 0.0
Gln
4.223GlnAla: 4.223 ± 1.481
0.845GlnCys: 0.845 ± 0.501
2.252GlnAsp: 2.252 ± 0.728
2.534GlnGlu: 2.534 ± 0.448
1.126GlnPhe: 1.126 ± 0.329
2.252GlnGly: 2.252 ± 0.541
1.689GlnHis: 1.689 ± 0.478
0.282GlnIle: 0.282 ± 0.271
0.845GlnLys: 0.845 ± 0.239
3.941GlnLeu: 3.941 ± 1.349
0.563GlnMet: 0.563 ± 0.245
0.845GlnAsn: 0.845 ± 0.37
1.126GlnPro: 1.126 ± 0.771
1.971GlnGln: 1.971 ± 0.366
2.815GlnArg: 2.815 ± 0.693
2.815GlnSer: 2.815 ± 0.829
1.971GlnThr: 1.971 ± 0.366
4.505GlnVal: 4.505 ± 0.854
0.845GlnTrp: 0.845 ± 0.425
0.563GlnTyr: 0.563 ± 0.327
0.0GlnXaa: 0.0 ± 0.0
Arg
9.291ArgAla: 9.291 ± 1.375
0.845ArgCys: 0.845 ± 0.514
2.252ArgAsp: 2.252 ± 0.992
4.505ArgGlu: 4.505 ± 0.902
1.408ArgPhe: 1.408 ± 0.432
4.505ArgGly: 4.505 ± 1.402
2.252ArgHis: 2.252 ± 1.018
2.252ArgIle: 2.252 ± 0.659
3.097ArgLys: 3.097 ± 0.834
7.038ArgLeu: 7.038 ± 0.965
1.689ArgMet: 1.689 ± 0.526
2.252ArgAsn: 2.252 ± 0.814
3.941ArgPro: 3.941 ± 1.568
1.689ArgGln: 1.689 ± 0.687
5.631ArgArg: 5.631 ± 1.432
5.068ArgSer: 5.068 ± 0.663
2.534ArgThr: 2.534 ± 0.544
6.757ArgVal: 6.757 ± 1.412
1.689ArgTrp: 1.689 ± 0.616
2.815ArgTyr: 2.815 ± 0.552
0.0ArgXaa: 0.0 ± 0.0
Ser
10.135SerAla: 10.135 ± 1.37
0.563SerCys: 0.563 ± 0.286
5.349SerAsp: 5.349 ± 1.11
4.505SerGlu: 4.505 ± 1.299
2.815SerPhe: 2.815 ± 0.91
4.786SerGly: 4.786 ± 0.982
2.534SerHis: 2.534 ± 0.64
1.408SerIle: 1.408 ± 1.067
1.971SerLys: 1.971 ± 0.303
8.446SerLeu: 8.446 ± 0.644
1.689SerMet: 1.689 ± 0.547
0.845SerAsn: 0.845 ± 0.637
6.757SerPro: 6.757 ± 1.593
2.534SerGln: 2.534 ± 0.887
6.194SerArg: 6.194 ± 0.754
5.349SerSer: 5.349 ± 1.102
3.378SerThr: 3.378 ± 0.553
4.505SerVal: 4.505 ± 1.267
0.845SerTrp: 0.845 ± 0.251
1.971SerTyr: 1.971 ± 0.687
0.0SerXaa: 0.0 ± 0.0
Thr
5.912ThrAla: 5.912 ± 1.143
0.282ThrCys: 0.282 ± 0.212
1.689ThrAsp: 1.689 ± 0.273
4.505ThrGlu: 4.505 ± 0.935
0.563ThrPhe: 0.563 ± 0.278
3.66ThrGly: 3.66 ± 1.025
0.845ThrHis: 0.845 ± 0.501
1.408ThrIle: 1.408 ± 0.537
1.408ThrLys: 1.408 ± 0.432
4.786ThrLeu: 4.786 ± 1.429
1.126ThrMet: 1.126 ± 0.497
1.408ThrAsn: 1.408 ± 0.692
3.378ThrPro: 3.378 ± 0.816
1.689ThrGln: 1.689 ± 0.957
2.534ThrArg: 2.534 ± 0.706
4.223ThrSer: 4.223 ± 0.566
3.378ThrThr: 3.378 ± 1.38
3.378ThrVal: 3.378 ± 0.748
1.126ThrTrp: 1.126 ± 0.452
1.408ThrTyr: 1.408 ± 0.527
0.0ThrXaa: 0.0 ± 0.0
Val
12.106ValAla: 12.106 ± 2.099
0.845ValCys: 0.845 ± 0.261
3.66ValAsp: 3.66 ± 0.776
5.068ValGlu: 5.068 ± 1.205
0.563ValPhe: 0.563 ± 0.425
4.786ValGly: 4.786 ± 1.471
3.378ValHis: 3.378 ± 1.396
1.971ValIle: 1.971 ± 0.527
3.378ValLys: 3.378 ± 0.916
9.009ValLeu: 9.009 ± 0.822
3.097ValMet: 3.097 ± 0.367
0.845ValAsn: 0.845 ± 0.697
3.66ValPro: 3.66 ± 1.389
3.941ValGln: 3.941 ± 1.366
6.757ValArg: 6.757 ± 1.39
5.912ValSer: 5.912 ± 0.738
2.815ValThr: 2.815 ± 0.954
6.757ValVal: 6.757 ± 1.134
0.845ValTrp: 0.845 ± 0.318
2.534ValTyr: 2.534 ± 0.425
0.0ValXaa: 0.0 ± 0.0
Trp
1.126TrpAla: 1.126 ± 0.354
0.282TrpCys: 0.282 ± 0.262
0.563TrpAsp: 0.563 ± 0.54
0.282TrpGlu: 0.282 ± 0.271
0.563TrpPhe: 0.563 ± 0.535
0.845TrpGly: 0.845 ± 0.51
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.845TrpLys: 0.845 ± 0.637
1.971TrpLeu: 1.971 ± 0.545
0.282TrpMet: 0.282 ± 0.212
0.282TrpAsn: 0.282 ± 0.482
0.563TrpPro: 0.563 ± 0.327
0.563TrpGln: 0.563 ± 0.286
1.689TrpArg: 1.689 ± 0.974
2.534TrpSer: 2.534 ± 0.969
0.845TrpThr: 0.845 ± 0.553
1.408TrpVal: 1.408 ± 0.455
0.563TrpTrp: 0.563 ± 0.557
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.941TyrAla: 3.941 ± 1.112
0.0TyrCys: 0.0 ± 0.0
1.408TyrAsp: 1.408 ± 0.335
2.252TyrGlu: 2.252 ± 1.104
1.408TyrPhe: 1.408 ± 0.75
3.097TyrGly: 3.097 ± 0.928
0.563TyrHis: 0.563 ± 0.54
0.563TyrIle: 0.563 ± 0.54
0.282TyrLys: 0.282 ± 0.212
3.941TyrLeu: 3.941 ± 0.516
0.845TyrMet: 0.845 ± 0.511
0.563TyrAsn: 0.563 ± 0.278
0.845TyrPro: 0.845 ± 0.425
0.845TyrGln: 0.845 ± 0.318
2.815TyrArg: 2.815 ± 1.086
2.815TyrSer: 2.815 ± 0.661
0.845TyrThr: 0.845 ± 0.535
2.815TyrVal: 2.815 ± 0.552
0.0TyrTrp: 0.0 ± 0.0
1.689TyrTyr: 1.689 ± 0.584
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3553 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski