Amino acid dipepetide frequency for Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.631AlaAla: 16.631 ± 0.124	1.061AlaCys: 1.061 ± 0.019	6.336AlaAsp: 6.336 ± 0.046	6.183AlaGlu: 6.183 ± 0.056	3.368AlaPhe: 3.368 ± 0.037	7.703AlaGly: 7.703 ± 0.053	2.751AlaHis: 2.751 ± 0.032	3.987AlaIle: 3.987 ± 0.038	5.077AlaLys: 5.077 ± 0.053	9.453AlaLeu: 9.453 ± 0.062	2.129AlaMet: 2.129 ± 0.021	3.45AlaAsn: 3.45 ± 0.033	7.175AlaPro: 7.175 ± 0.069	4.957AlaGln: 4.957 ± 0.04	7.215AlaArg: 7.215 ± 0.061	13.004AlaSer: 13.004 ± 0.082	6.702AlaThr: 6.702 ± 0.044	6.239AlaVal: 6.239 ± 0.047	1.264AlaTrp: 1.264 ± 0.018	2.25AlaTyr: 2.25 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	0.905CysAla: 0.905 ± 0.018	0.184CysCys: 0.184 ± 0.008	0.536CysAsp: 0.536 ± 0.012	0.433CysGlu: 0.433 ± 0.011	0.43CysPhe: 0.43 ± 0.011	0.709CysGly: 0.709 ± 0.017	0.256CysHis: 0.256 ± 0.009	0.549CysIle: 0.549 ± 0.01	0.403CysLys: 0.403 ± 0.011	1.002CysLeu: 1.002 ± 0.018	0.199CysMet: 0.199 ± 0.007	0.319CysAsn: 0.319 ± 0.01	0.544CysPro: 0.544 ± 0.015	0.342CysGln: 0.342 ± 0.01	0.646CysArg: 0.646 ± 0.014	0.821CysSer: 0.821 ± 0.015	0.599CysThr: 0.599 ± 0.014	0.617CysVal: 0.617 ± 0.013	0.144CysTrp: 0.144 ± 0.005	0.255CysTyr: 0.255 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.687AspAla: 7.687 ± 0.056	0.469AspCys: 0.469 ± 0.013	5.373AspAsp: 5.373 ± 0.077	4.746AspGlu: 4.746 ± 0.048	1.813AspPhe: 1.813 ± 0.024	4.097AspGly: 4.097 ± 0.039	1.299AspHis: 1.299 ± 0.022	2.016AspIle: 2.016 ± 0.027	2.257AspLys: 2.257 ± 0.029	4.851AspLeu: 4.851 ± 0.039	1.091AspMet: 1.091 ± 0.016	1.404AspAsn: 1.404 ± 0.022	3.449AspPro: 3.449 ± 0.035	2.02AspGln: 2.02 ± 0.023	3.293AspArg: 3.293 ± 0.033	4.357AspSer: 4.357 ± 0.043	2.88AspThr: 2.88 ± 0.023	3.711AspVal: 3.711 ± 0.035	0.764AspTrp: 0.764 ± 0.015	1.214AspTyr: 1.214 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	6.566GluAla: 6.566 ± 0.055	0.476GluCys: 0.476 ± 0.013	3.508GluAsp: 3.508 ± 0.033	4.133GluGlu: 4.133 ± 0.054	1.408GluPhe: 1.408 ± 0.023	3.131GluGly: 3.131 ± 0.032	1.393GluHis: 1.393 ± 0.02	2.059GluIle: 2.059 ± 0.026	2.443GluLys: 2.443 ± 0.036	5.203GluLeu: 5.203 ± 0.05	1.222GluMet: 1.222 ± 0.02	1.305GluAsn: 1.305 ± 0.017	2.719GluPro: 2.719 ± 0.033	2.605GluGln: 2.605 ± 0.032	4.109GluArg: 4.109 ± 0.041	3.945GluSer: 3.945 ± 0.033	2.685GluThr: 2.685 ± 0.027	3.067GluVal: 3.067 ± 0.033	0.72GluTrp: 0.72 ± 0.014	1.188GluTyr: 1.188 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.378PheAla: 3.378 ± 0.03	0.43PheCys: 0.43 ± 0.01	2.154PheAsp: 2.154 ± 0.024	1.803PheGlu: 1.803 ± 0.024	1.321PhePhe: 1.321 ± 0.02	2.856PheGly: 2.856 ± 0.041	0.783PheHis: 0.783 ± 0.014	1.181PheIle: 1.181 ± 0.018	1.124PheLys: 1.124 ± 0.019	2.817PheLeu: 2.817 ± 0.029	0.582PheMet: 0.582 ± 0.013	1.07PheAsn: 1.07 ± 0.018	1.529PhePro: 1.529 ± 0.021	1.089PheGln: 1.089 ± 0.017	1.82PheArg: 1.82 ± 0.021	2.65PheSer: 2.65 ± 0.023	1.622PheThr: 1.622 ± 0.021	2.261PheVal: 2.261 ± 0.025	0.481PheTrp: 0.481 ± 0.013	0.868PheTyr: 0.868 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	7.465GlyAla: 7.465 ± 0.059	0.682GlyCys: 0.682 ± 0.016	3.453GlyAsp: 3.453 ± 0.033	3.29GlyGlu: 3.29 ± 0.028	2.436GlyPhe: 2.436 ± 0.028	6.052GlyGly: 6.052 ± 0.066	1.621GlyHis: 1.621 ± 0.022	2.726GlyIle: 2.726 ± 0.029	3.221GlyLys: 3.221 ± 0.034	5.781GlyLeu: 5.781 ± 0.039	1.497GlyMet: 1.497 ± 0.025	2.04GlyAsn: 2.04 ± 0.04	3.324GlyPro: 3.324 ± 0.035	2.488GlyGln: 2.488 ± 0.029	4.265GlyArg: 4.265 ± 0.039	6.827GlySer: 6.827 ± 0.055	3.767GlyThr: 3.767 ± 0.034	4.104GlyVal: 4.104 ± 0.032	1.024GlyTrp: 1.024 ± 0.018	1.671GlyTyr: 1.671 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	3.0HisAla: 3.0 ± 0.031	0.263HisCys: 0.263 ± 0.009	1.525HisAsp: 1.525 ± 0.021	1.265HisGlu: 1.265 ± 0.018	0.859HisPhe: 0.859 ± 0.014	1.671HisGly: 1.671 ± 0.025	1.101HisHis: 1.101 ± 0.027	1.008HisIle: 1.008 ± 0.016	0.848HisLys: 0.848 ± 0.014	2.438HisLeu: 2.438 ± 0.028	0.465HisMet: 0.465 ± 0.012	0.74HisAsn: 0.74 ± 0.014	1.999HisPro: 1.999 ± 0.031	1.065HisGln: 1.065 ± 0.021	1.806HisArg: 1.806 ± 0.025	2.103HisSer: 2.103 ± 0.029	1.442HisThr: 1.442 ± 0.021	1.501HisVal: 1.501 ± 0.02	0.291HisTrp: 0.291 ± 0.008	0.553HisTyr: 0.553 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.041IleAla: 4.041 ± 0.034	0.501IleCys: 0.501 ± 0.012	2.591IleAsp: 2.591 ± 0.028	2.283IleGlu: 2.283 ± 0.027	1.393IlePhe: 1.393 ± 0.022	2.556IleGly: 2.556 ± 0.033	0.97IleHis: 0.97 ± 0.014	1.499IleIle: 1.499 ± 0.025	1.686IleLys: 1.686 ± 0.024	3.313IleLeu: 3.313 ± 0.034	0.707IleMet: 0.707 ± 0.014	1.295IleAsn: 1.295 ± 0.021	2.217IlePro: 2.217 ± 0.024	1.481IleGln: 1.481 ± 0.023	2.391IleArg: 2.391 ± 0.026	2.975IleSer: 2.975 ± 0.03	2.031IleThr: 2.031 ± 0.026	2.661IleVal: 2.661 ± 0.028	0.48IleTrp: 0.48 ± 0.012	0.92IleTyr: 0.92 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.678LysAla: 4.678 ± 0.054	0.352LysCys: 0.352 ± 0.011	2.358LysAsp: 2.358 ± 0.03	2.344LysGlu: 2.344 ± 0.033	1.023LysPhe: 1.023 ± 0.017	2.57LysGly: 2.57 ± 0.027	1.068LysHis: 1.068 ± 0.02	1.62LysIle: 1.62 ± 0.021	2.656LysLys: 2.656 ± 0.044	3.817LysLeu: 3.817 ± 0.038	0.908LysMet: 0.908 ± 0.017	1.191LysAsn: 1.191 ± 0.02	2.634LysPro: 2.634 ± 0.032	1.968LysGln: 1.968 ± 0.027	3.355LysArg: 3.355 ± 0.031	3.062LysSer: 3.062 ± 0.039	2.304LysThr: 2.304 ± 0.025	2.473LysVal: 2.473 ± 0.029	0.491LysTrp: 0.491 ± 0.01	0.91LysTyr: 0.91 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	10.019LeuAla: 10.019 ± 0.056	1.046LeuCys: 1.046 ± 0.019	5.628LeuAsp: 5.628 ± 0.045	4.963LeuGlu: 4.963 ± 0.044	2.954LeuPhe: 2.954 ± 0.035	6.036LeuGly: 6.036 ± 0.041	2.38LeuHis: 2.38 ± 0.025	3.21LeuIle: 3.21 ± 0.035	3.364LeuLys: 3.364 ± 0.035	8.444LeuLeu: 8.444 ± 0.067	1.549LeuMet: 1.549 ± 0.02	2.685LeuAsn: 2.685 ± 0.027	5.846LeuPro: 5.846 ± 0.044	3.776LeuGln: 3.776 ± 0.038	6.109LeuArg: 6.109 ± 0.052	7.522LeuSer: 7.522 ± 0.052	4.55LeuThr: 4.55 ± 0.035	5.691LeuVal: 5.691 ± 0.05	0.948LeuTrp: 0.948 ± 0.017	1.906LeuTyr: 1.906 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.168MetAla: 2.168 ± 0.024	0.187MetCys: 0.187 ± 0.007	1.117MetAsp: 1.117 ± 0.019	0.871MetGlu: 0.871 ± 0.014	0.533MetPhe: 0.533 ± 0.014	1.283MetGly: 1.283 ± 0.022	0.553MetHis: 0.553 ± 0.012	0.72MetIle: 0.72 ± 0.014	0.626MetLys: 0.626 ± 0.014	1.97MetLeu: 1.97 ± 0.025	0.449MetMet: 0.449 ± 0.012	0.519MetAsn: 0.519 ± 0.012	1.337MetPro: 1.337 ± 0.02	0.965MetGln: 0.965 ± 0.017	1.33MetArg: 1.33 ± 0.02	1.775MetSer: 1.775 ± 0.023	1.038MetThr: 1.038 ± 0.016	1.157MetVal: 1.157 ± 0.019	0.21MetTrp: 0.21 ± 0.008	0.406MetTyr: 0.406 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.69AsnAla: 3.69 ± 0.03	0.269AsnCys: 0.269 ± 0.008	1.706AsnAsp: 1.706 ± 0.023	1.482AsnGlu: 1.482 ± 0.019	1.001AsnPhe: 1.001 ± 0.017	2.539AsnGly: 2.539 ± 0.041	0.701AsnHis: 0.701 ± 0.015	1.212AsnIle: 1.212 ± 0.019	1.208AsnLys: 1.208 ± 0.02	2.651AsnLeu: 2.651 ± 0.025	0.628AsnMet: 0.628 ± 0.014	1.049AsnAsn: 1.049 ± 0.028	1.952AsnPro: 1.952 ± 0.024	1.053AsnGln: 1.053 ± 0.02	1.725AsnArg: 1.725 ± 0.022	2.266AsnSer: 2.266 ± 0.026	1.758AsnThr: 1.758 ± 0.023	2.005AsnVal: 2.005 ± 0.024	0.377AsnTrp: 0.377 ± 0.011	0.698AsnTyr: 0.698 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	7.8ProAla: 7.8 ± 0.07	0.467ProCys: 0.467 ± 0.013	3.116ProAsp: 3.116 ± 0.026	3.065ProGlu: 3.065 ± 0.027	1.944ProPhe: 1.944 ± 0.022	3.906ProGly: 3.906 ± 0.037	1.682ProHis: 1.682 ± 0.027	2.175ProIle: 2.175 ± 0.025	2.359ProLys: 2.359 ± 0.028	5.031ProLeu: 5.031 ± 0.043	1.023ProMet: 1.023 ± 0.017	1.963ProAsn: 1.963 ± 0.024	5.555ProPro: 5.555 ± 0.072	2.476ProGln: 2.476 ± 0.032	3.852ProArg: 3.852 ± 0.042	7.692ProSer: 7.692 ± 0.07	4.304ProThr: 4.304 ± 0.035	3.435ProVal: 3.435 ± 0.031	0.602ProTrp: 0.602 ± 0.013	1.272ProTyr: 1.272 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	4.687GlnAla: 4.687 ± 0.043	0.358GlnCys: 0.358 ± 0.01	2.216GlnAsp: 2.216 ± 0.027	2.02GlnGlu: 2.02 ± 0.028	0.996GlnPhe: 0.996 ± 0.018	2.429GlnGly: 2.429 ± 0.026	1.446GlnHis: 1.446 ± 0.025	1.596GlnIle: 1.596 ± 0.024	1.558GlnLys: 1.558 ± 0.022	4.032GlnLeu: 4.032 ± 0.036	0.879GlnMet: 0.879 ± 0.017	1.178GlnAsn: 1.178 ± 0.019	3.171GlnPro: 3.171 ± 0.038	3.311GlnGln: 3.311 ± 0.089	3.172GlnArg: 3.172 ± 0.029	3.325GlnSer: 3.325 ± 0.03	2.203GlnThr: 2.203 ± 0.022	2.147GlnVal: 2.147 ± 0.026	0.444GlnTrp: 0.444 ± 0.011	0.87GlnTyr: 0.87 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	6.801ArgAla: 6.801 ± 0.054	0.694ArgCys: 0.694 ± 0.015	3.51ArgAsp: 3.51 ± 0.036	3.368ArgGlu: 3.368 ± 0.037	2.243ArgPhe: 2.243 ± 0.028	3.845ArgGly: 3.845 ± 0.034	1.732ArgHis: 1.732 ± 0.026	2.868ArgIle: 2.868 ± 0.028	3.356ArgLys: 3.356 ± 0.036	5.903ArgLeu: 5.903 ± 0.046	1.34ArgMet: 1.34 ± 0.02	2.07ArgAsn: 2.07 ± 0.024	4.096ArgPro: 4.096 ± 0.041	2.853ArgGln: 2.853 ± 0.027	5.866ArgArg: 5.866 ± 0.062	6.574ArgSer: 6.574 ± 0.057	3.865ArgThr: 3.865 ± 0.038	3.328ArgVal: 3.328 ± 0.033	0.851ArgTrp: 0.851 ± 0.017	1.447ArgTyr: 1.447 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	11.221SerAla: 11.221 ± 0.07	0.751SerCys: 0.751 ± 0.016	4.94SerAsp: 4.94 ± 0.045	3.937SerGlu: 3.937 ± 0.037	2.905SerPhe: 2.905 ± 0.033	6.205SerGly: 6.205 ± 0.053	2.382SerHis: 2.382 ± 0.031	3.589SerIle: 3.589 ± 0.034	3.599SerLys: 3.599 ± 0.034	7.833SerLeu: 7.833 ± 0.054	1.742SerMet: 1.742 ± 0.025	2.976SerAsn: 2.976 ± 0.036	6.263SerPro: 6.263 ± 0.072	3.592SerGln: 3.592 ± 0.037	6.047SerArg: 6.047 ± 0.057	12.865SerSer: 12.865 ± 0.123	6.655SerThr: 6.655 ± 0.054	4.961SerVal: 4.961 ± 0.036	0.94SerTrp: 0.94 ± 0.017	1.849SerTyr: 1.849 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	6.529ThrAla: 6.529 ± 0.044	0.574ThrCys: 0.574 ± 0.012	2.844ThrAsp: 2.844 ± 0.028	2.488ThrGlu: 2.488 ± 0.023	1.93ThrPhe: 1.93 ± 0.02	3.788ThrGly: 3.788 ± 0.041	1.418ThrHis: 1.418 ± 0.02	2.287ThrIle: 2.287 ± 0.025	2.195ThrLys: 2.195 ± 0.025	5.217ThrLeu: 5.217 ± 0.038	1.051ThrMet: 1.051 ± 0.016	1.758ThrAsn: 1.758 ± 0.023	4.57ThrPro: 4.57 ± 0.043	2.117ThrGln: 2.117 ± 0.021	3.396ThrArg: 3.396 ± 0.035	6.143ThrSer: 6.143 ± 0.054	3.81ThrThr: 3.81 ± 0.038	3.224ThrVal: 3.224 ± 0.031	0.65ThrTrp: 0.65 ± 0.014	1.218ThrTyr: 1.218 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	6.388ValAla: 6.388 ± 0.043	0.686ValCys: 0.686 ± 0.014	3.715ValAsp: 3.715 ± 0.03	3.532ValGlu: 3.532 ± 0.034	1.987ValPhe: 1.987 ± 0.027	3.994ValGly: 3.994 ± 0.038	1.534ValHis: 1.534 ± 0.021	2.134ValIle: 2.134 ± 0.029	2.427ValLys: 2.427 ± 0.031	5.583ValLeu: 5.583 ± 0.046	1.049ValMet: 1.049 ± 0.017	1.668ValAsn: 1.668 ± 0.023	3.611ValPro: 3.611 ± 0.031	2.549ValGln: 2.549 ± 0.029	3.942ValArg: 3.942 ± 0.038	4.653ValSer: 4.653 ± 0.042	2.887ValThr: 2.887 ± 0.027	4.211ValVal: 4.211 ± 0.037	0.815ValTrp: 0.815 ± 0.018	1.405ValTyr: 1.405 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.018TrpAla: 1.018 ± 0.017	0.161TrpCys: 0.161 ± 0.006	0.727TrpAsp: 0.727 ± 0.013	0.556TrpGlu: 0.556 ± 0.011	0.421TrpPhe: 0.421 ± 0.01	0.701TrpGly: 0.701 ± 0.014	0.321TrpHis: 0.321 ± 0.009	0.634TrpIle: 0.634 ± 0.014	0.583TrpLys: 0.583 ± 0.012	1.187TrpLeu: 1.187 ± 0.018	0.298TrpMet: 0.298 ± 0.009	0.506TrpAsn: 0.506 ± 0.012	0.546TrpPro: 0.546 ± 0.013	0.545TrpGln: 0.545 ± 0.011	0.817TrpArg: 0.817 ± 0.016	1.041TrpSer: 1.041 ± 0.015	0.824TrpThr: 0.824 ± 0.015	0.601TrpVal: 0.601 ± 0.015	0.215TrpTrp: 0.215 ± 0.007	0.301TrpTyr: 0.301 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.26TyrAla: 2.26 ± 0.029	0.284TyrCys: 0.284 ± 0.008	1.436TyrAsp: 1.436 ± 0.022	1.121TyrGlu: 1.121 ± 0.017	0.856TyrPhe: 0.856 ± 0.015	1.663TyrGly: 1.663 ± 0.028	0.553TyrHis: 0.553 ± 0.011	0.924TyrIle: 0.924 ± 0.016	0.79TyrLys: 0.79 ± 0.017	2.098TyrLeu: 2.098 ± 0.027	0.408TyrMet: 0.408 ± 0.01	0.783TyrAsn: 0.783 ± 0.016	1.181TyrPro: 1.181 ± 0.019	0.786TyrGln: 0.786 ± 0.016	1.456TyrArg: 1.456 ± 0.019	1.652TyrSer: 1.652 ± 0.021	1.282TyrThr: 1.282 ± 0.021	1.376TyrVal: 1.376 ± 0.021	0.291TyrTrp: 0.291 ± 0.009	0.617TyrTyr: 0.617 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6640 proteins (4029301 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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