Amino acid dipepetide frequency for Mandrillus leucophaeus cytomegalovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.425AlaAla: 7.425 ± 0.714
2.113AlaCys: 2.113 ± 0.32
3.61AlaAsp: 3.61 ± 0.301
3.434AlaGlu: 3.434 ± 0.331
3.17AlaPhe: 3.17 ± 0.306
3.287AlaGly: 3.287 ± 0.403
1.849AlaHis: 1.849 ± 0.253
2.935AlaIle: 2.935 ± 0.312
2.231AlaLys: 2.231 ± 0.298
7.249AlaLeu: 7.249 ± 0.437
1.878AlaMet: 1.878 ± 0.223
2.231AlaAsn: 2.231 ± 0.221
3.815AlaPro: 3.815 ± 0.531
2.583AlaGln: 2.583 ± 0.356
3.962AlaArg: 3.962 ± 0.399
5.518AlaSer: 5.518 ± 0.496
4.96AlaThr: 4.96 ± 0.509
5.547AlaVal: 5.547 ± 0.501
1.057AlaTrp: 1.057 ± 0.192
2.172AlaTyr: 2.172 ± 0.24
0.0AlaXaa: 0.0 ± 0.0
Cys
1.438CysAla: 1.438 ± 0.253
0.763CysCys: 0.763 ± 0.187
1.174CysAsp: 1.174 ± 0.256
1.35CysGlu: 1.35 ± 0.273
1.086CysPhe: 1.086 ± 0.152
1.467CysGly: 1.467 ± 0.236
0.969CysHis: 0.969 ± 0.16
1.379CysIle: 1.379 ± 0.218
0.763CysLys: 0.763 ± 0.148
2.935CysLeu: 2.935 ± 0.336
0.528CysMet: 0.528 ± 0.099
1.145CysAsn: 1.145 ± 0.216
1.174CysPro: 1.174 ± 0.168
0.704CysGln: 0.704 ± 0.108
1.702CysArg: 1.702 ± 0.197
1.761CysSer: 1.761 ± 0.217
1.732CysThr: 1.732 ± 0.196
2.025CysVal: 2.025 ± 0.241
0.382CysTrp: 0.382 ± 0.116
0.851CysTyr: 0.851 ± 0.173
0.0CysXaa: 0.0 ± 0.0
Asp
3.317AspAla: 3.317 ± 0.394
0.763AspCys: 0.763 ± 0.162
4.05AspAsp: 4.05 ± 0.485
4.138AspGlu: 4.138 ± 0.493
1.79AspPhe: 1.79 ± 0.27
2.73AspGly: 2.73 ± 0.331
1.702AspHis: 1.702 ± 0.236
2.553AspIle: 2.553 ± 0.294
1.027AspLys: 1.027 ± 0.2
5.312AspLeu: 5.312 ± 0.447
1.409AspMet: 1.409 ± 0.209
1.761AspAsn: 1.761 ± 0.186
2.788AspPro: 2.788 ± 0.289
1.321AspGln: 1.321 ± 0.234
3.023AspArg: 3.023 ± 0.34
3.551AspSer: 3.551 ± 0.394
2.7AspThr: 2.7 ± 0.3
3.522AspVal: 3.522 ± 0.279
0.763AspTrp: 0.763 ± 0.147
1.732AspTyr: 1.732 ± 0.224
0.0AspXaa: 0.0 ± 0.0
Glu
3.61GluAla: 3.61 ± 0.323
1.145GluCys: 1.145 ± 0.164
3.551GluAsp: 3.551 ± 0.425
3.551GluGlu: 3.551 ± 0.34
1.614GluPhe: 1.614 ± 0.192
1.937GluGly: 1.937 ± 0.238
1.878GluHis: 1.878 ± 0.233
2.231GluIle: 2.231 ± 0.268
1.908GluLys: 1.908 ± 0.303
5.254GluLeu: 5.254 ± 0.433
1.233GluMet: 1.233 ± 0.176
2.524GluAsn: 2.524 ± 0.257
2.583GluPro: 2.583 ± 0.303
1.79GluGln: 1.79 ± 0.204
3.933GluArg: 3.933 ± 0.424
3.581GluSer: 3.581 ± 0.333
4.021GluThr: 4.021 ± 0.317
3.639GluVal: 3.639 ± 0.346
0.792GluTrp: 0.792 ± 0.132
1.291GluTyr: 1.291 ± 0.202
0.0GluXaa: 0.0 ± 0.0
Phe
2.407PheAla: 2.407 ± 0.284
1.321PheCys: 1.321 ± 0.235
1.585PheAsp: 1.585 ± 0.278
2.084PheGlu: 2.084 ± 0.232
2.26PhePhe: 2.26 ± 0.302
2.025PheGly: 2.025 ± 0.242
1.145PheHis: 1.145 ± 0.194
1.878PheIle: 1.878 ± 0.216
1.291PheLys: 1.291 ± 0.173
4.52PheLeu: 4.52 ± 0.359
1.233PheMet: 1.233 ± 0.206
1.732PheAsn: 1.732 ± 0.213
2.172PhePro: 2.172 ± 0.188
1.614PheGln: 1.614 ± 0.227
3.228PheArg: 3.228 ± 0.337
2.641PheSer: 2.641 ± 0.258
2.583PheThr: 2.583 ± 0.263
3.346PheVal: 3.346 ± 0.319
0.675PheTrp: 0.675 ± 0.163
1.79PheTyr: 1.79 ± 0.241
0.0PheXaa: 0.0 ± 0.0
Gly
3.023GlyAla: 3.023 ± 0.255
0.969GlyCys: 0.969 ± 0.189
2.201GlyAsp: 2.201 ± 0.266
2.876GlyGlu: 2.876 ± 0.315
1.79GlyPhe: 1.79 ± 0.236
3.14GlyGly: 3.14 ± 0.356
1.057GlyHis: 1.057 ± 0.181
2.143GlyIle: 2.143 ± 0.254
1.409GlyLys: 1.409 ± 0.174
4.931GlyLeu: 4.931 ± 0.376
0.822GlyMet: 0.822 ± 0.144
2.025GlyAsn: 2.025 ± 0.254
2.377GlyPro: 2.377 ± 0.334
1.702GlyGln: 1.702 ± 0.275
3.815GlyArg: 3.815 ± 0.432
3.962GlySer: 3.962 ± 0.278
2.876GlyThr: 2.876 ± 0.292
3.757GlyVal: 3.757 ± 0.353
0.558GlyTrp: 0.558 ± 0.107
2.025GlyTyr: 2.025 ± 0.232
0.0GlyXaa: 0.0 ± 0.0
His
2.407HisAla: 2.407 ± 0.277
0.704HisCys: 0.704 ± 0.137
1.467HisAsp: 1.467 ± 0.212
1.673HisGlu: 1.673 ± 0.274
1.057HisPhe: 1.057 ± 0.187
2.025HisGly: 2.025 ± 0.209
1.908HisHis: 1.908 ± 0.323
1.409HisIle: 1.409 ± 0.17
0.91HisLys: 0.91 ± 0.159
3.317HisLeu: 3.317 ± 0.387
0.528HisMet: 0.528 ± 0.12
1.35HisAsn: 1.35 ± 0.183
1.673HisPro: 1.673 ± 0.208
1.556HisGln: 1.556 ± 0.254
2.26HisArg: 2.26 ± 0.261
1.937HisSer: 1.937 ± 0.241
2.054HisThr: 2.054 ± 0.301
2.641HisVal: 2.641 ± 0.258
0.293HisTrp: 0.293 ± 0.084
1.233HisTyr: 1.233 ± 0.204
0.0HisXaa: 0.0 ± 0.0
Ile
2.788IleAla: 2.788 ± 0.27
1.203IleCys: 1.203 ± 0.192
1.937IleAsp: 1.937 ± 0.223
1.438IleGlu: 1.438 ± 0.202
2.289IlePhe: 2.289 ± 0.302
1.937IleGly: 1.937 ± 0.231
1.115IleHis: 1.115 ± 0.182
2.876IleIle: 2.876 ± 0.293
2.377IleLys: 2.377 ± 0.29
4.549IleLeu: 4.549 ± 0.427
1.262IleMet: 1.262 ± 0.187
1.702IleAsn: 1.702 ± 0.233
3.375IlePro: 3.375 ± 0.3
1.644IleGln: 1.644 ± 0.262
2.583IleArg: 2.583 ± 0.297
3.463IleSer: 3.463 ± 0.302
3.287IleThr: 3.287 ± 0.358
3.757IleVal: 3.757 ± 0.361
0.646IleTrp: 0.646 ± 0.15
2.348IleTyr: 2.348 ± 0.253
0.0IleXaa: 0.0 ± 0.0
Lys
2.348LysAla: 2.348 ± 0.329
1.027LysCys: 1.027 ± 0.136
1.673LysAsp: 1.673 ± 0.242
1.673LysGlu: 1.673 ± 0.251
1.174LysPhe: 1.174 ± 0.191
1.086LysGly: 1.086 ± 0.151
1.526LysHis: 1.526 ± 0.208
1.996LysIle: 1.996 ± 0.248
2.054LysLys: 2.054 ± 0.354
3.727LysLeu: 3.727 ± 0.413
0.792LysMet: 0.792 ± 0.145
2.025LysAsn: 2.025 ± 0.238
1.937LysPro: 1.937 ± 0.413
1.878LysGln: 1.878 ± 0.251
2.964LysArg: 2.964 ± 0.287
2.495LysSer: 2.495 ± 0.248
2.084LysThr: 2.084 ± 0.253
1.878LysVal: 1.878 ± 0.26
0.558LysTrp: 0.558 ± 0.146
1.115LysTyr: 1.115 ± 0.18
0.0LysXaa: 0.0 ± 0.0
Leu
6.633LeuAla: 6.633 ± 0.434
3.375LeuCys: 3.375 ± 0.305
3.962LeuAsp: 3.962 ± 0.361
4.373LeuGlu: 4.373 ± 0.378
4.549LeuPhe: 4.549 ± 0.401
4.931LeuGly: 4.931 ± 0.38
3.287LeuHis: 3.287 ± 0.35
4.49LeuIle: 4.49 ± 0.492
3.903LeuLys: 3.903 ± 0.39
10.859LeuLeu: 10.859 ± 0.676
2.436LeuMet: 2.436 ± 0.322
3.727LeuAsn: 3.727 ± 0.373
5.136LeuPro: 5.136 ± 0.365
3.786LeuGln: 3.786 ± 0.317
8.189LeuArg: 8.189 ± 0.669
7.396LeuSer: 7.396 ± 0.531
7.191LeuThr: 7.191 ± 0.515
6.662LeuVal: 6.662 ± 0.486
1.732LeuTrp: 1.732 ± 0.266
3.786LeuTyr: 3.786 ± 0.312
0.0LeuXaa: 0.0 ± 0.0
Met
2.143MetAla: 2.143 ± 0.266
0.558MetCys: 0.558 ± 0.127
0.969MetAsp: 0.969 ± 0.174
1.291MetGlu: 1.291 ± 0.198
1.35MetPhe: 1.35 ± 0.205
0.851MetGly: 0.851 ± 0.136
0.528MetHis: 0.528 ± 0.115
1.115MetIle: 1.115 ± 0.177
0.792MetLys: 0.792 ± 0.163
2.759MetLeu: 2.759 ± 0.31
0.763MetMet: 0.763 ± 0.155
0.998MetAsn: 0.998 ± 0.19
0.88MetPro: 0.88 ± 0.197
0.734MetGln: 0.734 ± 0.156
1.174MetArg: 1.174 ± 0.171
2.377MetSer: 2.377 ± 0.241
1.644MetThr: 1.644 ± 0.221
1.644MetVal: 1.644 ± 0.203
0.382MetTrp: 0.382 ± 0.099
0.792MetTyr: 0.792 ± 0.143
0.0MetXaa: 0.0 ± 0.0
Asn
3.17AsnAla: 3.17 ± 0.358
0.704AsnCys: 0.704 ± 0.151
2.054AsnAsp: 2.054 ± 0.255
1.996AsnGlu: 1.996 ± 0.205
1.262AsnPhe: 1.262 ± 0.199
1.526AsnGly: 1.526 ± 0.196
1.057AsnHis: 1.057 ± 0.203
2.377AsnIle: 2.377 ± 0.271
1.761AsnLys: 1.761 ± 0.182
3.845AsnLeu: 3.845 ± 0.397
0.792AsnMet: 0.792 ± 0.175
1.644AsnAsn: 1.644 ± 0.208
2.143AsnPro: 2.143 ± 0.293
1.321AsnGln: 1.321 ± 0.238
2.612AsnArg: 2.612 ± 0.267
3.023AsnSer: 3.023 ± 0.293
3.228AsnThr: 3.228 ± 0.323
3.874AsnVal: 3.874 ± 0.409
0.411AsnTrp: 0.411 ± 0.11
1.467AsnTyr: 1.467 ± 0.186
0.0AsnXaa: 0.0 ± 0.0
Pro
4.784ProAla: 4.784 ± 0.562
1.291ProCys: 1.291 ± 0.216
2.818ProAsp: 2.818 ± 0.326
3.228ProGlu: 3.228 ± 0.334
2.084ProPhe: 2.084 ± 0.267
2.935ProGly: 2.935 ± 0.354
2.113ProHis: 2.113 ± 0.302
2.054ProIle: 2.054 ± 0.305
1.79ProLys: 1.79 ± 0.322
4.843ProLeu: 4.843 ± 0.404
1.174ProMet: 1.174 ± 0.192
1.82ProAsn: 1.82 ± 0.294
5.87ProPro: 5.87 ± 0.927
1.908ProGln: 1.908 ± 0.33
3.874ProArg: 3.874 ± 0.432
5.107ProSer: 5.107 ± 0.421
3.551ProThr: 3.551 ± 0.458
3.874ProVal: 3.874 ± 0.363
0.616ProTrp: 0.616 ± 0.123
1.878ProTyr: 1.878 ± 0.246
0.0ProXaa: 0.0 ± 0.0
Gln
1.966GlnAla: 1.966 ± 0.228
0.939GlnCys: 0.939 ± 0.187
1.262GlnAsp: 1.262 ± 0.23
1.878GlnGlu: 1.878 ± 0.247
1.644GlnPhe: 1.644 ± 0.212
1.203GlnGly: 1.203 ± 0.174
1.585GlnHis: 1.585 ± 0.211
1.585GlnIle: 1.585 ± 0.219
1.585GlnLys: 1.585 ± 0.232
4.021GlnLeu: 4.021 ± 0.378
1.145GlnMet: 1.145 ± 0.18
1.908GlnAsn: 1.908 ± 0.225
2.612GlnPro: 2.612 ± 0.355
1.79GlnGln: 1.79 ± 0.283
2.935GlnArg: 2.935 ± 0.363
2.143GlnSer: 2.143 ± 0.259
2.7GlnThr: 2.7 ± 0.33
2.495GlnVal: 2.495 ± 0.309
0.382GlnTrp: 0.382 ± 0.098
1.086GlnTyr: 1.086 ± 0.147
0.0GlnXaa: 0.0 ± 0.0
Arg
4.579ArgAla: 4.579 ± 0.429
1.82ArgCys: 1.82 ± 0.196
4.08ArgAsp: 4.08 ± 0.387
3.61ArgGlu: 3.61 ± 0.343
2.289ArgPhe: 2.289 ± 0.268
3.434ArgGly: 3.434 ± 0.404
2.671ArgHis: 2.671 ± 0.326
2.583ArgIle: 2.583 ± 0.252
2.583ArgLys: 2.583 ± 0.269
7.044ArgLeu: 7.044 ± 0.581
1.35ArgMet: 1.35 ± 0.218
2.73ArgAsn: 2.73 ± 0.307
3.933ArgPro: 3.933 ± 0.421
3.698ArgGln: 3.698 ± 0.337
7.073ArgArg: 7.073 ± 0.596
4.549ArgSer: 4.549 ± 0.396
3.522ArgThr: 3.522 ± 0.36
4.461ArgVal: 4.461 ± 0.494
1.115ArgTrp: 1.115 ± 0.257
2.847ArgTyr: 2.847 ± 0.28
0.0ArgXaa: 0.0 ± 0.0
Ser
5.899SerAla: 5.899 ± 0.501
1.526SerCys: 1.526 ± 0.261
4.608SerAsp: 4.608 ± 0.369
3.757SerGlu: 3.757 ± 0.307
2.788SerPhe: 2.788 ± 0.218
4.08SerGly: 4.08 ± 0.379
2.231SerHis: 2.231 ± 0.287
3.493SerIle: 3.493 ± 0.293
2.671SerLys: 2.671 ± 0.258
7.132SerLeu: 7.132 ± 0.481
1.79SerMet: 1.79 ± 0.225
3.14SerAsn: 3.14 ± 0.367
5.048SerPro: 5.048 ± 0.481
2.847SerGln: 2.847 ± 0.288
5.166SerArg: 5.166 ± 0.398
8.218SerSer: 8.218 ± 0.842
4.813SerThr: 4.813 ± 0.721
4.96SerVal: 4.96 ± 0.412
0.88SerTrp: 0.88 ± 0.175
2.348SerTyr: 2.348 ± 0.331
0.0SerXaa: 0.0 ± 0.0
Thr
5.107ThrAla: 5.107 ± 0.532
1.467ThrCys: 1.467 ± 0.184
3.111ThrAsp: 3.111 ± 0.397
3.463ThrGlu: 3.463 ± 0.361
3.17ThrPhe: 3.17 ± 0.318
3.17ThrGly: 3.17 ± 0.262
2.26ThrHis: 2.26 ± 0.295
3.258ThrIle: 3.258 ± 0.338
2.671ThrLys: 2.671 ± 0.332
5.694ThrLeu: 5.694 ± 0.392
1.321ThrMet: 1.321 ± 0.223
2.524ThrAsn: 2.524 ± 0.42
3.962ThrPro: 3.962 ± 0.41
2.143ThrGln: 2.143 ± 0.266
3.199ThrArg: 3.199 ± 0.332
6.692ThrSer: 6.692 ± 0.86
8.159ThrThr: 8.159 ± 1.651
5.488ThrVal: 5.488 ± 0.408
0.91ThrTrp: 0.91 ± 0.188
1.585ThrTyr: 1.585 ± 0.228
0.0ThrXaa: 0.0 ± 0.0
Val
5.254ValAla: 5.254 ± 0.502
2.26ValCys: 2.26 ± 0.252
3.082ValAsp: 3.082 ± 0.327
3.463ValGlu: 3.463 ± 0.352
4.226ValPhe: 4.226 ± 0.374
3.052ValGly: 3.052 ± 0.395
1.937ValHis: 1.937 ± 0.246
3.786ValIle: 3.786 ± 0.313
2.524ValLys: 2.524 ± 0.298
6.721ValLeu: 6.721 ± 0.472
2.054ValMet: 2.054 ± 0.271
3.346ValAsn: 3.346 ± 0.395
4.08ValPro: 4.08 ± 0.362
2.201ValGln: 2.201 ± 0.282
4.432ValArg: 4.432 ± 0.41
5.753ValSer: 5.753 ± 0.4
5.136ValThr: 5.136 ± 0.404
5.019ValVal: 5.019 ± 0.467
0.822ValTrp: 0.822 ± 0.156
3.228ValTyr: 3.228 ± 0.364
0.0ValXaa: 0.0 ± 0.0
Trp
0.646TrpAla: 0.646 ± 0.133
0.47TrpCys: 0.47 ± 0.122
0.587TrpAsp: 0.587 ± 0.136
0.822TrpGlu: 0.822 ± 0.174
0.528TrpPhe: 0.528 ± 0.097
0.675TrpGly: 0.675 ± 0.176
0.411TrpHis: 0.411 ± 0.115
0.704TrpIle: 0.704 ± 0.137
0.587TrpLys: 0.587 ± 0.136
1.79TrpLeu: 1.79 ± 0.244
0.47TrpMet: 0.47 ± 0.113
0.352TrpAsn: 0.352 ± 0.097
0.675TrpPro: 0.675 ± 0.14
0.558TrpGln: 0.558 ± 0.123
1.145TrpArg: 1.145 ± 0.268
0.88TrpSer: 0.88 ± 0.17
0.704TrpThr: 0.704 ± 0.138
0.763TrpVal: 0.763 ± 0.117
0.323TrpTrp: 0.323 ± 0.102
0.763TrpTyr: 0.763 ± 0.158
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.084TyrAla: 2.084 ± 0.274
0.91TyrCys: 0.91 ± 0.133
2.172TyrAsp: 2.172 ± 0.273
1.966TyrGlu: 1.966 ± 0.229
1.409TyrPhe: 1.409 ± 0.202
1.966TyrGly: 1.966 ± 0.246
1.174TyrHis: 1.174 ± 0.169
1.732TyrIle: 1.732 ± 0.211
1.174TyrLys: 1.174 ± 0.197
3.933TyrLeu: 3.933 ± 0.33
0.734TyrMet: 0.734 ± 0.151
1.585TyrAsn: 1.585 ± 0.221
1.379TyrPro: 1.379 ± 0.194
1.086TyrGln: 1.086 ± 0.174
2.7TyrArg: 2.7 ± 0.263
2.348TyrSer: 2.348 ± 0.242
2.407TyrThr: 2.407 ± 0.3
3.023TyrVal: 3.023 ± 0.304
0.558TyrTrp: 0.558 ± 0.121
1.467TyrTyr: 1.467 ± 0.179
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 81 proteins (34073 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski